Nuclear EGFR as novel therapeutic target: Insights into nuclear translocation and function

Strahlentherapie und Onkologie

Volumn 186, Issue 1, 2010, Pages 1-6

  Dittmann, Klaus ^a   Mayer, Claus ^b   Rodemann, H Peter ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b NONE

Author keywords

Cetuximab; DNA repair; EGFR; Nuclear translocation; Tyrosine kinase inhibitor

Indexed keywords

CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN KINASE C EPSILON; PROTEIN TYROSINE KINASE INHIBITOR; ANTINEOPLASTIC AGENT; EGFR PROTEIN, HUMAN; MONOCLONAL ANTIBODY; PROTEIN TYROSINE KINASE;

CANCER RADIOTHERAPY; CELL CYCLE REGULATION; CELL LINE; CELL PROLIFERATION; COLORECTAL CANCER; CYTOSOL; DNA DAMAGE; DNA REPAIR; DRUG TARGETING; ENDOPLASMIC RETICULUM; GENE TRANSLOCATION; GENETIC TRANSCRIPTION; HUMAN; IONIZING RADIATION; LUNG NON SMALL CELL CANCER; PROTEIN FUNCTION; PROTEIN TRANSPORT; REVIEW; CAVEOLA; CELL CYCLE; CELL DIVISION; CELL NUCLEUS; CELL SURVIVAL; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; ONCOGENE SRC; PHYSIOLOGY; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; CAVEOLAE; CELL CYCLE; CELL DIVISION; CELL LINE; CELL NUCLEUS; CELL SURVIVAL; DNA DAMAGE; DNA REPAIR; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, SRC; HUMANS; PROTEIN KINASE C-EPSILON; PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TRANSLOCATION, GENETIC; TUMOR CELLS, CULTURED;

EID: 75649095683     PISSN: 01797158     EISSN: 1439099X     Source Type: Journal    
DOI: 10.1007/s00066-009-2026-4     Document Type: Review

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