-
1
-
-
0028858556
-
Human IL-17: A novel cytokine derived from T cells
-
Yao, Z. et al. Human IL-17: a novel cytokine derived from T cells. J. Immunol. 155, 5483-5486 (1995).
-
(1995)
J. Immunol.
, vol.155
, pp. 5483-5486
-
-
Yao, Z.1
-
2
-
-
15844402155
-
T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines
-
Fossiez, F. et al. T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J. Exp. Med. 183, 2593-2603 (1996).
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2593-2603
-
-
Fossiez, F.1
-
3
-
-
0027215897
-
CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene
-
Rouvier, E., Luciani, M. F., Mattei, M. G., Denizot, F & Golstein, P. CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. J. Immunol. 150, 5445-5456 (1993).
-
(1993)
J. Immunol.
, vol.150
, pp. 5445-5456
-
-
Rouvier, E.1
Luciani, M.F.2
Mattei, M.G.3
Denizot, F.4
Golstein, P.5
-
4
-
-
27544490377
-
+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nature Immunol. 6, 1123-1132 (2005).
-
(2005)
Nature Immunol.
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
-
5
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park, H. et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nature Immunol. 6, 1133-1141 (2005).
-
(2005)
Nature Immunol.
, vol.6
, pp. 1133-1141
-
-
Park, H.1
-
6
-
-
35348960243
-
Th17: The third member of the effector T cell trilogy
-
Bettelli, E., Korn, T. & Kuchroo, V. K. Th17: the third member of the effector T cell trilogy. Curr. Opin. Immunol. 19, 652-657 (2007).
-
(2007)
Curr. Opin. Immunol.
, vol.19
, pp. 652-657
-
-
Bettelli, E.1
Korn, T.2
Kuchroo, V.K.3
-
7
-
-
33744984785
-
Th17: An effector CD4 T cell lineage with regulatory T cell ties
-
Weaver, C. T., Harrington, L. E., Mangan, P. R., Gavrieli, M. & Murphy, K. M. Th17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity 24, 677-688 (2006).
-
(2006)
Immunity
, vol.24
, pp. 677-688
-
-
Weaver, C.T.1
Harrington, L.E.2
Mangan, P.R.3
Gavrieli, M.4
Murphy, K.M.5
-
8
-
-
69349093225
-
Interleukin-17 and type 17 helper T cells
-
Miossec, P., Korn, T. & Kuchroo, V. K. Interleukin-17 and type 17 helper T cells. N. Engl. J. Med. 361, 888-898 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 888-898
-
-
Miossec, P.1
Korn, T.2
Kuchroo, V.K.3
-
9
-
-
0032939156
-
Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
-
Chabaud, M. et al. Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. Arthritis Rheum. 42, 963-970 (1999).
-
(1999)
Arthritis Rheum.
, vol.42
, pp. 963-970
-
-
Chabaud, M.1
-
10
-
-
64849100544
-
Genome-wide comparison between IL-17A-and IL-17F-induced effects in human rheumatoid arthritis synoviocytes
-
Zrioual, S. et al. Genome-wide comparison between IL-17A-and IL-17F-induced effects in human rheumatoid arthritis synoviocytes. J. Immunol. 182, 3112-3120 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 3112-3120
-
-
Zrioual, S.1
-
11
-
-
0036144194
-
IL-17: Prototype member of an emerging cytokine family
-
Aggarwal, S. & Gurney, A. L. IL-17: prototype member of an emerging cytokine family. J. Leukoc. Biol. 71, 1-8 (2002).
-
(2002)
J. Leukoc. Biol.
, vol.71
, pp. 1-8
-
-
Aggarwal, S.1
Gurney, A.L.2
-
12
-
-
17944368518
-
IL-17s Adopt A Cystine Knot Fold: Structure and Activity of A Novel Cytokine IL-17F and Implications for Receptor Binding
-
Hymowitz, S. G. et al. IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F and implications for receptor binding. EMBO J. 20, 5332-5341 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 5332-5341
-
-
Hymowitz, S.G.1
-
13
-
-
34250305962
-
+ T cells
-
+ T cells. J. Biol. Chem. 282, 13447-13455 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 13447-13455
-
-
Wright, J.F.1
-
14
-
-
43549110961
-
Regulation of inflammatory responses by IL-17F
-
Yang, X. O. et al. Regulation of inflammatory responses by IL-17F. J. Exp. Med. 205, 1063-1075 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1063-1075
-
-
Yang, X.O.1
-
15
-
-
80755133721
-
Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor e
-
Chang, S. H. et al. Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E. Immunity 35, 611-621 (2011).
-
(2011)
Immunity
, vol.35
, pp. 611-621
-
-
Chang, S.H.1
-
16
-
-
34547820890
-
IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells
-
Wang, Y. H. et al. IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells. J. Exp. Med. 204, 1837-1847 (2007).
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1837-1847
-
-
Wang, Y.H.1
-
17
-
-
33846458998
-
IL-25 regulates Th17 function in autoimmune inflammation
-
Kleinschek, M. A. et al. IL-25 regulates Th17 function in autoimmune inflammation. J. Exp. Med. 204, 161-170 (2007).
-
(2007)
J. Exp. Med.
, vol.204
, pp. 161-170
-
-
Kleinschek, M.A.1
-
18
-
-
0029555301
-
Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor
-
Yao, Z. et al. Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 3, 811-821 (1995).
-
(1995)
Immunity
, vol.3
, pp. 811-821
-
-
Yao, Z.1
-
19
-
-
0031282513
-
Molecular characterization of the human interleukin (IL)-17 receptor
-
Yao, Z. et al. Molecular characterization of the human interleukin (IL)-17 receptor. Cytokine 9, 794-800 (1997).
-
(1997)
Cytokine
, vol.9
, pp. 794-800
-
-
Yao, Z.1
-
20
-
-
33745297345
-
Cutting edge: Interleukin 17 signals through a heteromeric receptor complex
-
Toy, D. et al. Cutting edge: interleukin 17 signals through a heteromeric receptor complex. J. Immunol. 177, 36-39 (2006).
-
(2006)
J. Immunol.
, vol.177
, pp. 36-39
-
-
Toy, D.1
-
21
-
-
70449718758
-
Structural basis of receptor sharing by interleukin 17 cytokines
-
Ely, L. K., Fischer, S. & Garcia, K. C. Structural basis of receptor sharing by interleukin 17 cytokines. Nature Immunol. 10, 1245-1251 (2009).
-
(2009)
Nature Immunol.
, vol.10
, pp. 1245-1251
-
-
Ely, L.K.1
Fischer, S.2
Garcia, K.C.3
-
22
-
-
59449105964
-
IL-17RD (Sef or IL-17RLM) interacts with IL-17 receptor and mediates IL-17 signaling
-
Rong, Z. et al. IL-17RD (Sef or IL-17RLM) interacts with IL-17 receptor and mediates IL-17 signaling. Cell Res. 19, 208-215 (2009).
-
(2009)
Cell Res.
, vol.19
, pp. 208-215
-
-
Rong, Z.1
-
23
-
-
81255158786
-
IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens
-
Song, X. et al. IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens. Nature Immunol. 12, 1151-1158 (2011).
-
(2011)
Nature Immunol.
, vol.12
, pp. 1151-1158
-
-
Song, X.1
-
24
-
-
81255158784
-
IL-17C regulates the innate immune function of epithelial cells in an autocrine manner
-
Ramirez-Carrozzi, V. et al. IL-17C regulates the innate immune function of epithelial cells in an autocrine manner. Nature Immunol. 12, 1159-1166 (2011).
-
(2011)
Nature Immunol.
, vol.12
, pp. 1159-1166
-
-
Ramirez-Carrozzi, V.1
-
25
-
-
33846022750
-
Act1 adaptor protein is an immediate and essential signaling component of interleukin-17 receptor
-
Chang, S. H., Park, H. & Dong, C. Act1 adaptor protein is an immediate and essential signaling component of interleukin-17 receptor. J. Biol. Chem. 281, 35603-35607 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 35603-35607
-
-
Chang, S.H.1
Park, H.2
Dong, C.3
-
26
-
-
34247873196
-
The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease
-
Qian, Y et al. The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. Nature Immunol. 8, 247-256 (2007).
-
(2007)
Nature Immunol.
, vol.8
, pp. 247-256
-
-
Qian, Y.1
-
27
-
-
79953310900
-
Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes
-
Hot, A. & Miossec, P. Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes. Ann. Rheum. Dis. 70, 727-732 (2011).
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 727-732
-
-
Hot, A.1
Miossec, P.2
-
28
-
-
4944267710
-
IL-17A augments TNF-a-induced IL-6 expression in airway smooth muscle by enhancing mRNA stability
-
Henness, S. et al. IL-17A augments TNF-a-induced IL-6 expression in airway smooth muscle by enhancing mRNA stability. J. Allergy Clin. Immunol. 114, 958-964 (2004).
-
(2004)
J. Allergy Clin. Immunol.
, vol.114
, pp. 958-964
-
-
Henness, S.1
-
29
-
-
35748973565
-
IL-17 Enhances Chemokine Gene Expression Through MRNA Stabilization
-
Hartupee, J., Liu, C, Novotny, M., Li, X. & Hamilton, T IL-17 enhances chemokine gene expression through mRNA stabilization. J. Immunol. 179, 4135-4141 (2007).
-
(2007)
J. Immunol.
, vol.179
, pp. 4135-4141
-
-
Hartupee, J.1
Liu, C.2
Novotny, M.3
Li, X.4
Hamilton, T.5
-
30
-
-
33747662347
-
Identification of common transcriptional regulatory elements in interleukin-17 target genes
-
Shen, F, Hu, Z., Goswami, J. & Gaffen, S. L. Identification of common transcriptional regulatory elements in interleukin-17 target genes. J. Biol. Chem. 281, 24138-24148 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 24138-24148
-
-
Shen, F.1
Hu, Z.2
Goswami, J.3
Gaffen, S.L.4
-
31
-
-
80455163028
-
Persistent stimulation with interleukin-17 desensitizes cells through SCFß-TrCP-mediated degradation of Act1
-
Shi, P. et al. Persistent stimulation with interleukin-17 desensitizes cells through SCFß-TrCP-mediated degradation of Act1. Sci. Signal. 4, ra73 (2011).
-
(2011)
Sci. Signal.
, vol.4
-
-
Shi, P.1
-
32
-
-
78649404973
-
Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling
-
Zhu, S. et al. Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling. J. Exp. Med. 207, 2647-2662 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2647-2662
-
-
Zhu, S.1
-
33
-
-
80455176377
-
A CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17-and IL-25-induced inflammation
-
Liu, C. et al. A CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17-and IL-25-induced inflammation. Sci. Signal. 4, ra72 (2011).
-
(2011)
Sci. Signal.
, vol.4
-
-
Liu, C.1
-
34
-
-
30744437656
-
Evidence for ligand-independent multimerization of the IL-17 receptor
-
Kramer, J. M. et al. Evidence for ligand-independent multimerization of the IL-17 receptor. J. Immunol. 176, 711-715 (2006).
-
(2006)
J. Immunol.
, vol.176
, pp. 711-715
-
-
Kramer, J.M.1
-
35
-
-
0034541221
-
Microbial lipopeptides induce the production of IL-17 in Th cells
-
Infante-Duarte, C, Horton, H. F, Byrne, M. C. & Kamradt, T. Microbial lipopeptides induce the production of IL-17 in Th cells. J. Immunol. 165, 6107-6115 (2000).
-
(2000)
J. Immunol.
, vol.165
, pp. 6107-6115
-
-
Infante-Duarte, C.1
Horton, H.F.2
Byrne, M.C.3
Kamradt, T.4
-
36
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
Aggarwal, S., Ghilardi, N., Xie, M. H., de Sauvage, F. J. & Gurney, A. L. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem. 278, 1910-1914 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.H.3
De Sauvage, F.J.4
Gurney, A.L.5
-
37
-
-
0242584872
-
Cutting edge: Roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection
-
Happel, K. I. et al. Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection. J. Immunol. 170, 4432-4436 (2003).
-
(2003)
J. Immunol.
, vol.170
, pp. 4432-4436
-
-
Happel, K.I.1
-
38
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua, D. J. et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 421, 744-748 (2003).
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
-
39
-
-
9644291539
-
IL-12 and IL-23: Master regulators of innate and adaptive immunity
-
Langrish, C. L. et al. IL-12 and IL-23: master regulators of innate and adaptive immunity. Immunol. Rev. 202, 96-105 (2004).
-
(2004)
Immunol. Rev.
, vol.202
, pp. 96-105
-
-
Langrish, C.L.1
-
40
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish, C. L. et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 201, 233-240 (2005).
-
(2005)
J. Exp. Med.
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
-
41
-
-
33646560950
-
H17 lineage
-
H17 lineage. Nature 441, 231-234 (2006).
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
-
42
-
-
33646577466
-
H17 and regulatory T cells
-
H17 and regulatory T cells. Nature 441, 235-238 (2006).
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
-
43
-
-
32244442562
-
TGFß in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M. & Stockinger, B. TGFß in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24, 179-189 (2006).
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
44
-
-
34247593586
-
STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
-
Yang, X. O. et al. STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J. Biol. Chem. 282, 9358-9363 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 9358-9363
-
-
Yang, X.O.1
-
45
-
-
79251618802
-
Genetic controls of Th17 cell differentiation and plasticity
-
Dong, C. Genetic controls of Th17 cell differentiation and plasticity. Exp. Mol. Med. 43, 1-6 (2011).
-
(2011)
Exp. Mol. Med.
, vol.43
, pp. 1-6
-
-
Dong, C.1
-
46
-
-
68649088121
-
Interleukin-1 and IL-23 induce innate IL-17 production from yô T cells, amplifying Th17 responses and autoimmunity
-
Sutton, C. E. et al. Interleukin-1 and IL-23 induce innate IL-17 production from yô T cells, amplifying Th17 responses and autoimmunity. Immunity 31, 331-341 (2009).
-
(2009)
Immunity
, vol.31
, pp. 331-341
-
-
Sutton, C.E.1
-
47
-
-
68649126866
-
Interleukin-17-producing yô T cells selectively expand in response to pathogen products and environmental signals
-
Martin, B., Hirota, K., Cua, D. J., Stockinger, B. & Veldhoen, M. Interleukin-17-producing yô T cells selectively expand in response to pathogen products and environmental signals. Immunity 31, 321-330 (2009).
-
(2009)
Immunity
, vol.31
, pp. 321-330
-
-
Martin, B.1
Hirota, K.2
Cua, D.J.3
Stockinger, B.4
Veldhoen, M.5
-
48
-
-
64049089798
-
Critical regulation of early Th17 cell differentiation by interleukin-1 signaling
-
Chung, Y et al. Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity 30, 576-587 (2009).
-
(2009)
Immunity
, vol.30
, pp. 576-587
-
-
Chung, Y.1
-
49
-
-
36248970701
-
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells
-
Awasthi, A. et al. A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. Nature Immunol. 8, 1380-1389 (2007).
-
(2007)
Nature Immunol.
, vol.8
, pp. 1380-1389
-
-
Awasthi, A.1
-
50
-
-
77958584113
-
H17 cells in the absence of TGF-ß signalling
-
H17 cells in the absence of TGF-ß signalling. Nature 467, 967-971 (2010).
-
(2010)
Nature
, vol.467
, pp. 967-971
-
-
Ghoreschi, K.1
-
51
-
-
33749138039
-
IL-17 Production Is Dominated by Yô T Cells Rather Than CD4 T Cells during Mycobacterium Tuberculosis Infection
-
Lockhart, E., Green, A. M. & Flynn, J. L. IL-17 production is dominated by yô T cells rather than CD4 T cells during Mycobacterium tuberculosis infection. J. Immunol. 177, 4662-4669 (2006).
-
(2006)
J. Immunol.
, vol.177
, pp. 4662-4669
-
-
Lockhart, E.1
Green, A.M.2
Flynn, J.L.3
-
52
-
-
33947677787
-
+ Yô T Cells Control Early Infiltration of Neutrophils after Escherichia Coli Infection Via IL-17 Production
-
+ yô T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production. J. Immunol. 178, 4466-4472 (2007).
-
(2007)
J. Immunol.
, vol.178
, pp. 4466-4472
-
-
Shibata, K.1
Yamada, H.2
Hara, H.3
Kishihara, K.4
Yoshikai, Y.5
-
53
-
-
34249059942
-
neg iNKT cell population involved in airway neutrophilia
-
neg iNKT cell population involved in airway neutrophilia. J. Exp. Med. 204, 995-1001 (2007).
-
(2007)
J. Exp. Med.
, vol.204
, pp. 995-1001
-
-
Michel, M.L.1
-
54
-
-
39549106479
-
Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17
-
Pichavant, M. et al. Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17. J. Exp. Med. 205, 385-393 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, pp. 385-393
-
-
Pichavant, M.1
-
55
-
-
80052923989
-
IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression
-
Milpied, P. et al. IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression. Blood 118, 2993-3002 (2011).
-
(2011)
Blood
, vol.118
, pp. 2993-3002
-
-
Milpied, P.1
-
56
-
-
77954143695
-
Innate IL-17-producing cells: The sentinels of the immune system
-
Cua, D. J. & Tato, C. M. Innate IL-17-producing cells: the sentinels of the immune system. Nature Rev Immunol. 10, 479-489 (2010).
-
(2010)
Nature Rev Immunol.
, vol.10
, pp. 479-489
-
-
Cua, D.J.1
Tato, C.M.2
-
57
-
-
0038276938
-
Mast cells produce interleukin-25 upon FcsRI-mediated activation
-
Ikeda, K. et al. Mast cells produce interleukin-25 upon FcsRI-mediated activation. Blood 101, 3594-3596 (2003).
-
(2003)
Blood
, vol.101
, pp. 3594-3596
-
-
Ikeda, K.1
-
58
-
-
65249185481
-
Murine mast cells secrete a unique profile of cytokines and prostaglandins in response to distinct TLR2 ligands
-
Mrabet-Dahbi, S., Metz, M., Dudeck, A., Zuberbier, T & Maurer, M. Murine mast cells secrete a unique profile of cytokines and prostaglandins in response to distinct TLR2 ligands. Exp. Dermatol. 18, 437-444 (2009).
-
(2009)
Exp. Dermatol.
, vol.18
, pp. 437-444
-
-
Mrabet-Dahbi, S.1
Metz, M.2
Dudeck, A.3
Zuberbier, T.4
Maurer, M.5
-
59
-
-
79959584686
-
Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis
-
Lin, A. M. et al. Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis. J. Immunol. 187, 490-500 (2011).
-
(2011)
J. Immunol.
, vol.187
, pp. 490-500
-
-
Lin, A.M.1
-
60
-
-
77951636478
-
Mast cells express IL-17A in rheumatoid arthritis synovium
-
Hueber, A. J. et al. Mast cells express IL-17A in rheumatoid arthritis synovium. J. Immunol. 184, 3336-3340 (2010).
-
(2010)
J. Immunol.
, vol.184
, pp. 3336-3340
-
-
Hueber, A.J.1
-
61
-
-
80052015098
-
IL-17A expression is localised to both mononuclear and polymorphonuclear synovial cell infiltrates
-
Moran, E. M. et al. IL-17A expression is localised to both mononuclear and polymorphonuclear synovial cell infiltrates. PLoS ONE 6, e24048 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Moran, E.M.1
-
62
-
-
84855291352
-
Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis
-
Noordenbos, T. et al. Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis. Arthritis Rheum. 64, 99-109 (2012).
-
(2012)
Arthritis Rheum.
, vol.64
, pp. 99-109
-
-
Noordenbos, T.1
-
63
-
-
78049519396
-
IL-17A is increased in the serum and in spinal cord CD8 and mast cells of ALS patients
-
Fiala, M. et al. IL-17A is increased in the serum and in spinal cord CD8 and mast cells of ALS patients. J. Neuroinflamm. 7, 76 (2010).
-
(2010)
J. Neuroinflamm.
, vol.7
, pp. 76
-
-
Fiala, M.1
-
64
-
-
67649835097
-
Expression of interleukin-17RC protein in normal human tissues
-
Ge, D. & You, Z. Expression of interleukin-17RC protein in normal human tissues. Int. Arch. Med. 1, 19 (2008).
-
(2008)
Int. Arch. Med.
, vol.1
, pp. 19
-
-
Ge, D.1
You, Z.2
-
65
-
-
23844545819
-
Requirement of IL-17 receptor signaling in radiation-resistant cells in the joint for full progression of destructive synovitis
-
Lubberts, E. et al. Requirement of IL-17 receptor signaling in radiation-resistant cells in the joint for full progression of destructive synovitis. J. Immunol. 175, 3360-3368 (2005).
-
(2005)
J. Immunol.
, vol.175
, pp. 3360-3368
-
-
Lubberts, E.1
-
66
-
-
0037333960
-
Interleukin-17 in rheumatoid arthritis: If T cells were to contribute to inflammation and destruction through synergy
-
Miossec, P. Interleukin-17 in rheumatoid arthritis: if T cells were to contribute to inflammation and destruction through synergy. Arthritis Rheum. 48, 594-601 (2003).
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 594-601
-
-
Miossec, P.1
-
67
-
-
79961122266
-
Tumor necrosis factor-interleukin-17 interplay induces S100A8, interleukin-1 ß, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: Rationale for combination treatment during arthritis
-
Koenders, M. I. et al. Tumor necrosis factor-interleukin-17 interplay induces S100A8, interleukin-1 ß, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: rationale for combination treatment during arthritis. Arthritis Rheum. 63, 2329-2339 (2011).
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 2329-2339
-
-
Koenders, M.I.1
-
68
-
-
78650764391
-
Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production
-
van Hamburg, J. P. et al. Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production. Arthritis Rheum. 63, 73-83 (2011).
-
(2011)
Arthritis Rheum.
, vol.63
, pp. 73-83
-
-
Van Hamburg, J.P.1
-
69
-
-
84863228492
-
Bone marrow-and synovium-derived mesenchymal cells promote Th-17 cells through caspase-1 activation: Contribution to rheumatoid arthritis chronicity
-
Eljaafari, A. et al. Bone marrow-and synovium-derived mesenchymal cells promote Th-17 cells through caspase-1 activation: contribution to rheumatoid arthritis chronicity. Arthritis Rheum. 64, 2147-2157 (2012).
-
(2012)
Arthritis Rheum.
, vol.64
, pp. 2147-2157
-
-
Eljaafari, A.1
-
70
-
-
0034966563
-
The combination of tumor necrosis factor a blockade with interleukin-1 and interleukin-17 blockade is more effective for controlling synovial inflammation and bone resorption in an ex vivo model
-
Chabaud, M. & Miossec, P. The combination of tumor necrosis factor a blockade with interleukin-1 and interleukin-17 blockade is more effective for controlling synovial inflammation and bone resorption in an ex vivo model. Arthritis Rheum. 44, 1293-1303 (2001).
-
(2001)
Arthritis Rheum.
, vol.44
, pp. 1293-1303
-
-
Chabaud, M.1
Miossec, P.2
-
71
-
-
38349178776
-
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice
-
Hsu, H. C. et al. Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nature Immunol. 9, 166-175 (2008).
-
(2008)
Nature Immunol.
, vol.9
, pp. 166-175
-
-
Hsu, H.C.1
-
72
-
-
78149438748
-
Role of interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression
-
Toh, M. L. et al. Role of interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression. PLoS ONE 5, e13416 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Toh, M.L.1
-
73
-
-
0031802932
-
Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines
-
Chabaud, M., Fossiez, F, Taupin, J. L. & Miossec, P. Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines. J. Immunol. 161, 409-414 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 409-414
-
-
Chabaud, M.1
Fossiez, F.2
Taupin, J.L.3
Miossec, P.4
-
74
-
-
0032403506
-
IL-17 stimulates granulopoiesis in mice: Use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokines
-
Schwarzenberger, P. et al. IL-17 stimulates granulopoiesis in mice: use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokines. J. Immunol. 161, 6383-6389 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 6383-6389
-
-
Schwarzenberger, P.1
-
75
-
-
0034193959
-
Requirement of endogenous stem cell factor and granulocyte-colony- stimulating factor for IL-17-mediated granulopoiesis
-
Schwarzenberger, P. et al. Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis. J. Immunol. 164, 4783-4789 (2000).
-
(2000)
J. Immunol.
, vol.164
, pp. 4783-4789
-
-
Schwarzenberger, P.1
-
76
-
-
79961077100
-
Mechanisms controlling Th17 cytokine expression and host defense
-
McAleer, J. P. & Kolls, J. K. Mechanisms controlling Th17 cytokine expression and host defense. J. Leukoc. Biol. 90, 263-270 (2011).
-
(2011)
J. Leukoc. Biol.
, vol.90
, pp. 263-270
-
-
McAleer, J.P.1
Kolls, J.K.2
-
77
-
-
17944364849
-
Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense
-
Ye, P. et al. Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense. J. Exp. Med. 194, 519-527 (2001).
-
(2001)
J. Exp. Med.
, vol.194
, pp. 519-527
-
-
Ye, P.1
-
78
-
-
0035761425
-
Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule-deficient mice
-
Forlow, S. B. et al. Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule-deficient mice. Blood 98, 3309-3314 (2001).
-
(2001)
Blood
, vol.98
, pp. 3309-3314
-
-
Forlow, S.B.1
-
79
-
-
15244344110
-
Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17
-
Stark, M. A. et al. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity 22, 285-294 (2005).
-
(2005)
Immunity
, vol.22
, pp. 285-294
-
-
Stark, M.A.1
-
80
-
-
54949142477
-
Cytokine-mediated regulation of antimicrobial proteins
-
Kolls, J. K., McCray, P. B. Jr & Chan, Y. R. Cytokine-mediated regulation of antimicrobial proteins. Nature Rev. Immunol. 8, 829-835 (2008).
-
(2008)
Nature Rev. Immunol.
, vol.8
, pp. 829-835
-
-
Kolls, J.K.1
McCray, Jr.P.B.2
Chan, Y.R.3
-
81
-
-
3242814586
-
Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice
-
Huang, W., Na, L, Fidel, P. L. & Schwarzenberger, P. Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J. Infect. Dis. 190, 624-631 (2004).
-
(2004)
J. Infect. Dis.
, vol.190
, pp. 624-631
-
-
Huang, W.1
Na, L.2
Fidel, P.L.3
Schwarzenberger, P.4
-
82
-
-
63049138176
-
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis
-
Conti, H. R. et al. Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis. J. Exp. Med. 206, 299-311 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 299-311
-
-
Conti, H.R.1
-
83
-
-
0036361437
-
Interleukin 17: An example for gene therapy as a tool to study cytokine mediated regulation of hematopoiesis
-
Schwarzenberger, P. & Kolls, J. K. Interleukin 17: an example for gene therapy as a tool to study cytokine mediated regulation of hematopoiesis. J. Cell Biochem. 85 (Suppl. 38), 88-95 (2002).
-
(2002)
J. Cell Biochem.
, vol.85
, Issue.SUPPL. 38
, pp. 88-95
-
-
Schwarzenberger, P.1
Kolls, J.K.2
-
84
-
-
58149231532
-
Differential roles of interleukin-17A and-17F in host defense against mucoepithelial bacterial infection and allergic responses
-
Ishigame, H. et al. Differential roles of interleukin-17A and-17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity 30, 108-119 (2009).
-
(2009)
Immunity
, vol.30
, pp. 108-119
-
-
Ishigame, H.1
-
85
-
-
77951861324
-
IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice
-
Cho, J. S. et al. IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. J. Clin. Invest. 120, 1762-1773 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1762-1773
-
-
Cho, J.S.1
-
86
-
-
34249869268
-
Interleukin-23 (IL-23)-IL-17 cytokine axis in murine Pneumocystis carinii infection
-
Rudner, X. L., Happel, K. I., Young, E. A. & Shellito, J. E. Interleukin-23 (IL-23)-IL-17 cytokine axis in murine Pneumocystis carinii infection. Infect. Immun. 75, 3055-3061 (2007).
-
(2007)
Infect. Immun.
, vol.75
, pp. 3055-3061
-
-
Rudner, X.L.1
Happel, K.I.2
Young, E.A.3
Shellito, J.E.4
-
87
-
-
79251491762
-
Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice
-
Wuthrich, M. et al. Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice. J. Clin. Invest. 121, 554-568 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 554-568
-
-
Wuthrich, M.1
-
88
-
-
79953284685
-
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity
-
Puel, A. et al. Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science 332, 65-68 (2011).
-
(2011)
Science
, vol.332
, pp. 65-68
-
-
Puel, A.1
-
89
-
-
84857764063
-
Sensing of mammalian IL-17A regulates fungal adaptation and virulence
-
Zelante, T. et al. Sensing of mammalian IL-17A regulates fungal adaptation and virulence. Nature Commun. 3, 683 (2012).
-
Nature Commun.
, vol.3
, Issue.683
, pp. 2012
-
-
Zelante, T.1
-
90
-
-
40049098958
-
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia
-
Aujla, S. J. et al. IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nature Med. 14, 275-281 (2008).
-
(2008)
Nature Med.
, vol.14
, pp. 275-281
-
-
Aujla, S.J.1
-
91
-
-
55149116512
-
The role of cytokines in the initiation, expansion, and control of cellular immunity to tuberculosis
-
Cooper, A. M. & Khader, S. A. The role of cytokines in the initiation, expansion, and control of cellular immunity to tuberculosis. Immunol. Rev. 226, 191-204 (2008).
-
(2008)
Immunol. Rev.
, vol.226
, pp. 191-204
-
-
Cooper, A.M.1
Khader, S.A.2
-
92
-
-
70449501815
-
Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis
-
Lin, Y. et al. Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis. Immunity 31, 799-810 (2009).
-
(2009)
Immunity
, vol.31
, pp. 799-810
-
-
Lin, Y.1
-
93
-
-
34248562792
-
+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
-
+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nature Immunol. 8, 369-377 (2007).
-
(2007)
Nature Immunol.
, vol.8
, pp. 369-377
-
-
Khader, S.A.1
-
94
-
-
0036192064
-
Overexpression of IL-17 in the knee joint of collagen type II immunized mice promotes collagen arthritis and aggravates joint destruction
-
Lubberts, E. et al. Overexpression of IL-17 in the knee joint of collagen type II immunized mice promotes collagen arthritis and aggravates joint destruction. Inflamm. Res. 51, 102-104 (2002).
-
(2002)
Inflamm. Res.
, vol.51
, pp. 102-104
-
-
Lubberts, E.1
-
95
-
-
1042267236
-
Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion
-
Lubberts, E. et al. Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion. Arthritis Rheum. 50, 650-659 (2004).
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 650-659
-
-
Lubberts, E.1
-
96
-
-
26844554064
-
Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis
-
Koenders, M. I. et al. Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis. Arthritis Rheum. 52, 3239-3247 (2005).
-
(2005)
Arthritis Rheum
, vol.52
, pp. 3239-3247
-
-
Koenders, M.I.1
-
97
-
-
33646490259
-
Interleukin-17 acts independently of TNF-α under arthritic conditions
-
Koenders, M. I. et al. Interleukin-17 acts independently of TNF-α under arthritic conditions. J. Immunol. 176, 6262-6269 (2006).
-
(2006)
J. Immunol.
, vol.176
, pp. 6262-6269
-
-
Koenders, M.I.1
-
98
-
-
33846889522
-
A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis
-
Krueger, G. G. et al. A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis. N. Engl. J. Med. 356, 580-592 (2007).
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 580-592
-
-
Krueger, G.G.1
-
99
-
-
34547774225
-
Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis
-
Capon, F. et al. Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. Hum. Genet. 122, 201-206 (2007).
-
(2007)
Hum. Genet.
, vol.122
, pp. 201-206
-
-
Capon, F.1
-
100
-
-
33846906224
-
H17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
-
H17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 445, 648-651 (2007).
-
(2007)
Nature
, vol.445
, pp. 648-651
-
-
Zheng, Y.1
-
101
-
-
37549011317
-
Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses
-
Zaba, L. C. et al. Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses. J. Exp. Med. 204, 3183-3194 (2007).
-
(2007)
J. Exp. Med.
, vol.204
, pp. 3183-3194
-
-
Zaba, L.C.1
-
102
-
-
58149316658
-
+ T Cell Trafficking and Development by IFN-γ: Mechanism and Pathological Relevance in Psoriasis
-
+ T cell trafficking and development by IFN-γ: mechanism and pathological relevance in psoriasis. J. Immunol. 181, 4733-4741 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 4733-4741
-
-
Kryczek, I.1
-
103
-
-
42149087160
-
Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells
-
Lowes, M. A. et al. Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells. J. Invest. Dermatol. 128, 1207-1211 (2008).
-
(2008)
J. Invest. Dermatol.
, vol.128
, pp. 1207-1211
-
-
Lowes, M.A.1
-
104
-
-
47249125726
-
Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes
-
Pene, J. et al. Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. J. Immunol. 180, 7423-7430 (2008).
-
(2008)
J. Immunol.
, vol.180
, pp. 7423-7430
-
-
Pene, J.1
-
105
-
-
70349753261
-
Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: Implications for psoriasis pathogenesis
-
Harper, E. G. et al. Th17 cytokines stimulate CCL20 expression in keratinocytes in vitro and in vivo: implications for psoriasis pathogenesis. J. Invest. Dermatol. 129, 2175-2183 (2009).
-
(2009)
J. Invest. Dermatol.
, vol.129
, pp. 2175-2183
-
-
Harper, E.G.1
-
106
-
-
79959207913
-
+ cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response
-
+ cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response. Arthritis Res. Ther. 13, R95 (2011).
-
(2011)
Arthritis Res. Ther.
, vol.13
-
-
Appel, H.1
-
107
-
-
44349136821
-
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
-
Fisher, S. A. et al. Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nature Genet. 40, 710-712 (2008).
-
(2008)
Nature Genet.
, vol.40
, pp. 710-712
-
-
Fisher, S.A.1
-
108
-
-
34249030920
-
IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease
-
Dubinsky, M. C. et al. IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease. Inflamm. Bowel Dis. 13, 511-515 (2007).
-
(2007)
Inflamm. Bowel Dis.
, vol.13
, pp. 511-515
-
-
Dubinsky, M.C.1
-
109
-
-
56549104968
-
IL-23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease
-
Kobayashi, T. et al. IL-23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease. Gut 57, 1682-1689 (2008).
-
(2008)
Gut
, vol.57
, pp. 1682-1689
-
-
Kobayashi, T.1
-
110
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen, D. et al. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J. Clin. Invest. 11 6, 1310-1316 (2006).
-
(2006)
J. Clin. Invest.
, vol.11
, pp. 61310-61316
-
-
Yen, D.1
-
111
-
-
34250026960
-
Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice
-
Elson, C. O. et al. Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice. Gastroenterology 132, 2359-2370 (2007).
-
(2007)
Gastroenterology
, vol.132
, pp. 2359-2370
-
-
Elson, C.O.1
-
112
-
-
65749091607
-
A protective function for interleukin 17A in T cell-mediated intestinal inflammation
-
O'Connor, W. Jr et al. A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nature Immunol. 10, 603-609 (2009).
-
(2009)
Nature Immunol.
, vol.10
, pp. 603-609
-
-
O'Connor, Jr.W.1
-
113
-
-
0035944838
-
Infliximab-induced aseptic meningitis
-
Marotte, H., Charrin, J. E. & Miossec, P. Infliximab-induced aseptic meningitis. Lancet 358, 1784 (2001).
-
(2001)
Lancet
, vol.358
, pp. 1784
-
-
Marotte, H.1
Charrin, J.E.2
Miossec, P.3
-
114
-
-
59249098388
-
Inflammatory demyelinating events following treatment with anti-tumor necrosis factor
-
Fromont, A., De Seze, J., Fleury, M. C., Maillefert, J. F. & Moreau, T. Inflammatory demyelinating events following treatment with anti-tumor necrosis factor. Cytokine 45, 55-57 (2009).
-
(2009)
Cytokine
, vol.45
, pp. 55-57
-
-
Fromont, A.1
De Seze, J.2
Fleury, M.C.3
Maillefert, J.F.4
Moreau, T.5
-
115
-
-
39749173780
-
The blood-brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells
-
Ifergan, I. et al. The blood-brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells. Brain 131, 785-799 (2008).
-
(2008)
Brain
, vol.131
, pp. 785-799
-
-
Ifergan, I.1
-
116
-
-
33751243318
-
Development of an anti-IL-17A auto-vaccine that prevents experimental auto-immune encephalomyelitis
-
Uyttenhove, C. & Van Snick, J. Development of an anti-IL-17A auto-vaccine that prevents experimental auto-immune encephalomyelitis. Eur. J. Immunol. 36, 2868-2874 (2006).
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 2868-2874
-
-
Uyttenhove, C.1
Van Snick, J.2
-
117
-
-
0036105484
-
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
-
Lock, C. et al. Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nature Med. 8, 500-508 (2002).
-
(2002)
Nature Med.
, vol.8
, pp. 500-508
-
-
Lock, C.1
-
118
-
-
41249095660
-
Cardiovascular disease in patients with rheumatoid arthritis: Results from the QUEST-RA study
-
Naranjo, A. et al. Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study. Arthritis Res. Ther. 10, R30 (2008).
-
(2008)
Arthritis Res. Ther.
, vol.10
-
-
Naranjo, A.1
-
119
-
-
0346030568
-
Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosus
-
Roman, M. J. et al. Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosus. N. Engl. J. Med. 349, 2399-2406 (2003).
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 2399-2406
-
-
Roman, M.J.1
-
120
-
-
79952351318
-
Tumour necrosis factor antagonist use and associated risk reduction of cardiovascular events among patients with rheumatoid arthritis
-
Greenberg, J. D. et al. Tumour necrosis factor antagonist use and associated risk reduction of cardiovascular events among patients with rheumatoid arthritis. Ann. Rheum. Dis. 70, 576-582 (2011).
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 576-582
-
-
Greenberg, J.D.1
-
121
-
-
84859491118
-
Combination of IL-17 and TNFα induces a pro-inflammatory, pro-coagulant and pro-thrombotic phenotype in human endothelial cells
-
Hot, A., Lenief, V. & Miossec, P. Combination of IL-17 and TNFα induces a pro-inflammatory, pro-coagulant and pro-thrombotic phenotype in human endothelial cells. Ann. Rheum. Dis. 71, 768-776 (2012).
-
(2012)
Ann. Rheum. Dis.
, vol.71
, pp. 768-776
-
-
Hot, A.1
Lenief, V.2
Miossec, P.3
-
122
-
-
80051471106
-
Interleukin 17 as a novel predictor of vascular function in rheumatoid arthritis
-
Marder, W. et al. Interleukin 17 as a novel predictor of vascular function in rheumatoid arthritis. Ann. Rheum. Dis. 70, 1550-1555 (2011).
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 1550-1555
-
-
Marder, W.1
-
123
-
-
33845585620
-
Role of interleukin-17 and interleukin-17-induced cytokines interleukin-6 and interleukin-8 in unstable coronary artery disease
-
Hashmi, S. & Zeng, Q. T. Role of interleukin-17 and interleukin-17-induced cytokines interleukin-6 and interleukin-8 in unstable coronary artery disease. Coron. Artery Dis. 17, 699-706 (2006).
-
(2006)
Coron. Artery Dis.
, vol.17
, pp. 699-706
-
-
Hashmi, S.1
Zeng, Q.T.2
-
124
-
-
64549126102
-
Interleukin-17 and interferon-γ are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells
-
Eid, R. E. et al. Interleukin-17 and interferon-γ are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation 11 9, 1424-1432 (2009).
-
(2009)
Circulation
, vol.11
, pp. 91424-91432
-
-
Eid, R.E.1
-
125
-
-
69249213893
-
Attenuated atherosclerosis upon IL-17R signaling disruption in LDLr deficient mice
-
van Es, T. et al. Attenuated atherosclerosis upon IL-17R signaling disruption in LDLr deficient mice. Biochem. Biophys. Res. Commun. 388, 261-265 (2009).
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.388
, pp. 261-265
-
-
Van Es, T.1
-
126
-
-
77951485998
-
Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient mice
-
Smith, E. et al. Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient mice. Circulation 121, 1746-1755 (2010).
-
(2010)
Circulation
, vol.121
, pp. 1746-1755
-
-
Smith, E.1
-
127
-
-
78149490050
-
IL-17A is proatherogenic in high-fat diet-induced and Chlamydia pneumoniae infection-accelerated atherosclerosis in mice
-
Chen, S. et al. IL-17A is proatherogenic in high-fat diet-induced and Chlamydia pneumoniae infection-accelerated atherosclerosis in mice. J. Immunol. 185, 5619-5627 (2010).
-
(2010)
J. Immunol.
, vol.185
, pp. 5619-5627
-
-
Chen, S.1
-
128
-
-
21244455537
-
Role of IL-17A IL-17F and the IL-17 Receptor in Regulating Growth-related Oncogene-α and Granulocyte Colony-stimulating Factor in Bronchial Epithelium: Implications for Airway Inflammation in Cystic Fibrosis
-
McAllister, F. et al. Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-α and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis. J. Immunol. 175, 404-412 (2005).
-
(2005)
J. Immunol.
, vol.175
, pp. 404-412
-
-
McAllister, F.1
-
129
-
-
25444435646
-
Interleukin-17A mRNA and protein expression within cells from the human bronchoalveolar space after exposure to organic dust
-
Ivanov, S., Palmberg, L., Venge, P., Larsson, K. & Linden, A. Interleukin-17A mRNA and protein expression within cells from the human bronchoalveolar space after exposure to organic dust. Respir. Res. 6, 44 (2005).
-
(2005)
Respir. Res.
, vol.6
, pp. 44
-
-
Ivanov, S.1
Palmberg, L.2
Venge, P.3
Larsson, K.4
Linden, A.5
-
130
-
-
33751180809
-
IL-17 mRNA in sputum of asthmatic patients: Linking T cell driven inflammation and granulocytic influx?
-
Bullens, D. M. et al. IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx? Respir. Res. 7, 135 (2006).
-
(2006)
Respir. Res.
, vol.7
, pp. 135
-
-
Bullens, D.M.1
-
131
-
-
56149097181
-
TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice
-
McKinley, L. et al. TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice. J. Immunol. 181, 4089-4097 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 4089-4097
-
-
McKinley, L.1
-
132
-
-
77956955243
-
Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma
-
Lajoie, S. et al. Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma. Nature Immunol. 11, 928-935 (2010).
-
(2010)
Nature Immunol.
, vol.11
, pp. 928-935
-
-
Lajoie, S.1
-
133
-
-
67349203306
-
H17-associated cytokines (IL-17A and IL-17F) in severe asthma
-
H17-associated cytokines (IL-17A and IL-17F) in severe asthma. J. Allergy Clin. Immunol. 123, 1185-1187 (2009).
-
(2009)
J. Allergy Clin. Immunol.
, vol.123
, pp. 1185-1187
-
-
Al-Ramli, W.1
-
134
-
-
80051553123
-
The Th17 pathway in cystic fibrosis lung disease
-
Tan, H. L. et al. The Th17 pathway in cystic fibrosis lung disease. Am. J. Respir. Crit. Care Med. 184, 252-258 (2011).
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.184
, pp. 252-258
-
-
Tan, H.L.1
-
135
-
-
79957613753
-
IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke
-
Chen, K. et al. IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke. PLoS ONE 6, e20333 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Chen, K.1
-
136
-
-
67650653218
-
T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients
-
Di Stefano, A. et al. T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients. Clin. Exp. Immunol. 157, 316-324 (2009).
-
(2009)
Clin. Exp. Immunol.
, vol.157
, pp. 316-324
-
-
Di Stefano, A.1
-
137
-
-
78349269946
-
Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD
-
Doe, C. et al. Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD. Chest 138, 1140-1147 (2010).
-
(2010)
Chest
, vol.138
, pp. 1140-1147
-
-
Doe, C.1
-
138
-
-
79953732157
-
CD8 positive T cells express IL-17 in patients with chronic obstructive pulmonary disease
-
Chang, Y. et al. CD8 positive T cells express IL-17 in patients with chronic obstructive pulmonary disease. Respir. Res. 12, 43 (2011).
-
(2011)
Respir. Res.
, vol.12
, pp. 43
-
-
Chang, Y.1
-
139
-
-
80054974908
-
The expression of Foxp3 and ROR gamma t in lung tissues from normal smokers and chronic obstructive pulmonary disease patients
-
Chu, S. et al. The expression of Foxp3 and ROR gamma t in lung tissues from normal smokers and chronic obstructive pulmonary disease patients. Int. Immunopharmacol. 11, 1780-1788 (2011).
-
(2011)
Int. Immunopharmacol.
, vol.11
, pp. 1780-1788
-
-
Chu, S.1
-
140
-
-
84856068597
-
Cigarette Smoke Induction of Osteopontin (SPP1) Mediates TH17 Inflammation in Human and Experimental Emphysema
-
Shan, M. et al. Cigarette smoke induction of osteopontin (SPP1) mediates TH17 inflammation in human and experimental emphysema. Sci. Transl. Med 4, 117ra1 19 (2012).
-
(2012)
Sci. Transl. Med
, vol.4
, pp. 117-119
-
-
Shan, M.1
-
141
-
-
59849115870
-
Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis
-
Simonian, P. L. et al. Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis. J. Immunol. 182, 657-665 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 657-665
-
-
Simonian, P.L.1
-
142
-
-
65249134949
-
Interleukin-17-mediated immunopathogenesis in experimental hypersensitivity pneumonitis
-
Joshi, A. D. et al. Interleukin-17-mediated immunopathogenesis in experimental hypersensitivity pneumonitis. Am. J. Respir. Crit. Care Med. 179, 705-716 (2009).
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.179
, pp. 705-716
-
-
Joshi, A.D.1
-
143
-
-
77949516122
-
Bleomycin and IL-1 ß-mediated pulmonary fibrosis is IL-17A dependent
-
Wilson, M. S. et al. Bleomycin and IL-1 ß-mediated pulmonary fibrosis is IL-17A dependent. J. Exp. Med. 207, 535-552 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 535-552
-
-
Wilson, M.S.1
-
144
-
-
80053070208
-
Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-ß 1-dependent and-independent mechanisms
-
Mi, S. et al. Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-ß 1-dependent and-independent mechanisms. J. Immunol. 187, 3003-3014 (2011).
-
(2011)
J. Immunol.
, vol.187
, pp. 3003-3014
-
-
Mi, S.1
-
145
-
-
45249097325
-
Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: Implications for Th17-mediated inflammation in auto-immunity
-
Wong, C. K. et al. Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity. Clin. Immunol. 127, 385-393 (2008).
-
(2008)
Clin. Immunol.
, vol.127
, pp. 385-393
-
-
Wong, C.K.1
-
146
-
-
17444401702
-
Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice
-
Tartour, E. et al. Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice. Cancer Res. 59, 3698-3704 (1999).
-
(1999)
Cancer Res.
, vol.59
, pp. 3698-3704
-
-
Tartour, E.1
-
147
-
-
0037376738
-
Interleukin-17 increases the effects of IL-1 ß on muscle cells: Arguments for the role of T cells in the pathogenesis of myositis
-
Chevrel, G. et al. Interleukin-17 increases the effects of IL-1 ß on muscle cells: arguments for the role of T cells in the pathogenesis of myositis. J. Neuroimmunol. 137, 125-133 (2003).
-
(2003)
J. Neuroimmunol.
, vol.137
, pp. 125-133
-
-
Chevrel, G.1
-
148
-
-
47249092218
-
Skewed distribution of Th17 lymphocytes in patients with Wegener's granulomatosis in remission
-
Abdulahad, W H., Stegeman, C. A., Limburg, P. C. & Kallenberg, C. G. Skewed distribution of Th17 lymphocytes in patients with Wegener's granulomatosis in remission. Arthritis Rheum. 58, 2196-2205 (2008).
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 2196-2205
-
-
Abdulahad, W.H.1
Stegeman, C.A.2
Limburg, P.C.3
Kallenberg, C.G.4
-
149
-
-
77950196277
-
H17 cells in tumour immunity and immunotherapy
-
H17 cells in tumour immunity and immunotherapy. Nature Rev. Immunol. 10, 248-256 (2010).
-
(2010)
Nature Rev. Immunol.
, vol.10
, pp. 248-256
-
-
Zou, W.1
Restifo, N.P.2
-
150
-
-
84856400832
-
Newsmaker: Lycera
-
Garber, K. Newsmaker: lycera. Nature Biotech. 29, 679 (2011).
-
(2011)
Nature Biotech.
, vol.29
, pp. 679
-
-
Garber, K.1
-
151
-
-
79955538365
-
H17 cell differentiation by antagonizing RORyt activity
-
H17 cell differentiation by antagonizing RORyt activity. Nature 472, 486-490 (2011).
-
(2011)
Nature
, vol.472
, pp. 486-490
-
-
Huh, J.R.1
-
152
-
-
79955526989
-
H17 differentiation and autoimmunity by a synthetic ROR ligand
-
H17 differentiation and autoimmunity by a synthetic ROR ligand. Nature 472, 491-494 (2011).
-
(2011)
Nature
, vol.472
, pp. 491-494
-
-
Solt, L.A.1
-
153
-
-
79959538387
-
Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORy t protein
-
Xu, T. et al. Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORy t protein. J. Biol. Chem. 286, 22707-22710 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 22707-22710
-
-
Xu, T.1
-
154
-
-
79954603523
-
PI3KÔ drives the pathogenesis of experimental autoimmune encephalomyelitis by inhibiting effector T cell apoptosis and promoting Th17 differentiation
-
Haylock-Jacobs, S. et al. PI3KÔ drives the pathogenesis of experimental autoimmune encephalomyelitis by inhibiting effector T cell apoptosis and promoting Th17 differentiation. J. Autoimmun. 36, 278-287 (2011).
-
(2011)
J. Autoimmun.
, vol.36
, pp. 278-287
-
-
Haylock-Jacobs, S.1
-
155
-
-
84856808226
-
World Bispecific Antibody Summit, September 27-28, 2011, Boston, MA
-
Dhimolea, E. & Reichert, J. M. World Bispecific Antibody Summit, September 27-28, 2011, Boston, MA. MAbs 4, 4-13 (2012).
-
(2012)
MAbs
, vol.4
, pp. 4-13
-
-
Dhimolea, E.1
Reichert, J.M.2
-
156
-
-
0030847902
-
Interleukin-17 and its receptor
-
Spriggs, M. K. Interleukin-17 and its receptor. J. Clin. Immunol. 17, 366-369 (1997).
-
(1997)
J. Clin. Immunol.
, vol.17
, pp. 366-369
-
-
Spriggs, M.K.1
-
157
-
-
68849084891
-
Structure and signalling in the IL-17 receptor family
-
Gaffen, S. L. Structure and signalling in the IL-17 receptor family. Nature Rev. Immunol. 9, 556-567 (2009).
-
(2009)
Nature Rev. Immunol.
, vol.9
, pp. 556-567
-
-
Gaffen, S.L.1
-
158
-
-
40449113569
-
+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood
-
+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood. J. Immunol. 180, 655-663 (2008).
-
(2008)
J. Immunol.
, vol.180
, pp. 655-663
-
-
Zrioual, S.1
-
159
-
-
84864481289
-
Inhibition of IL-6 function corrects Th17/Treg imbalance in rheumatoid arthritis patients
-
Samson, M. et al. Inhibition of IL-6 function corrects Th17/Treg imbalance in rheumatoid arthritis patients. Arthritis Rheum. 64, 2499-2503 (2012).
-
(2012)
Arthritis Rheum.
, vol.64
, pp. 2499-2503
-
-
Samson, M.1
-
160
-
-
77958072084
-
Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
-
Hueber, W. et al. Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci. Transl. Med. 2, 52ra72 (2010).
-
(2010)
Sci. Transl. Med.
, vol.2
-
-
Hueber, W.1
-
161
-
-
79958798030
-
The anti-IL17A monoclonal antibody secukinumab (AIN457) showed good safety and efficacy in the treatment of active ankylosing spondylitis
-
Abstract L3847
-
Baeten, D. et al. The anti-IL17A monoclonal antibody secukinumab (AIN457) showed good safety and efficacy in the treatment of active ankylosing spondylitis. Arthritis Rheum. 62, Abstract L3847 (2010).
-
(2010)
Arthritis Rheum.
, vol.62
-
-
Baeten, D.1
-
162
-
-
77950535421
-
LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase i randomized, double-blind, placebo-controlled, proof-of-concept study
-
Genovese, M. C. et al. LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a phase I randomized, double-blind, placebo-controlled, proof-of-concept study. Arthritis Rheum. 62, 929-939 (2010).
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 929-939
-
-
Genovese, M.C.1
-
163
-
-
84859017988
-
Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis
-
Papp, K. A. et al. Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis. N. Engl. J. Med. 366, 1181-1189 (2012).
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 1181-1189
-
-
Papp, K.A.1
-
164
-
-
84868680312
-
Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: Unexpected results of a randomised, double-blind placebo-controlled trial
-
17 May 2012 (doi: 10.1136/gutjnl-2011-301668
-
Hueber, W. et al. Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial. Gut 17 May 2012 (doi: 10.1136/gutjnl-2011-301668).
-
Gut
-
-
Hueber, W.1
-
165
-
-
83655181156
-
Are Th17 cells in the gut pathogenic or protective?
-
Symons, A., Budelsky, A. L. & Towne, J. E. Are Th17 cells in the gut pathogenic or protective? Mucosal Immunol. 5, 4-6 (2012).
-
(2012)
Mucosal Immunol.
, vol.5
, pp. 4-6
-
-
Symons, A.1
Budelsky, A.L.2
Towne, J.E.3
-
166
-
-
0037214556
-
Interleukin-17: An emerging role in lung inflammation
-
Kolls, J. K., Kanaly, S. T. & Ramsay, A. J. Interleukin-17: an emerging role in lung inflammation. Am. J. Respir. Cell Mol. Biol. 28, 9-11 (2003).
-
(2003)
Am. J. Respir. Cell Mol. Biol.
, vol.28
, pp. 9-11
-
-
Kolls, J.K.1
Kanaly, S.T.2
Ramsay, A.J.3
-
167
-
-
84859073115
-
Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis
-
Leonardi, C. et al. Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis. N. Engl. J. Med. 366, 1190-1199 (2012).
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 1190-1199
-
-
Leonardi, C.1
-
168
-
-
34547415613
-
Interleukin-17 in fashion, at last: Ten years after its description, its cellular source has been identified
-
Miossec, P. Interleukin-17 in fashion, at last: ten years after its description, its cellular source has been identified. Arthritis Rheum. 56, 2111-2115 (2007).
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 2111-2115
-
-
Miossec, P.1
|