Requirement of IL-17 receptor signaling in radiation-resistant cells in the joint for full progression of destructive synovitis

Journal of Immunology

Volumn 175, Issue 5, 2005, Pages 3360-3368

  Lubberts, Erik ^a,b,d   Schwarzenberger, Paul ^a   Huang, Weitao ^a   Schurr, Jill R ^a   Peschon, Jacques J ^c   Van Den Berg, Wim B ^b   Kolls, Jay K ^a,e  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c AMGEN INC   (United States)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; COLLAGENASE 3; CYTOKINE; INTERLEUKIN 17; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN RECEPTOR; SELECTIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BACTERIAL CELL WALL; BONE EROSION; BONE MARROW; CELL PROTECTION; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; DNA MICROARRAY; DOWN REGULATION; FEMALE; KNEE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIVITY; SIGNAL TRANSDUCTION; STREPTOCOCCUS; SYNOVITIS; SYNOVIUM;

EID: 23844545819     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.5.3360     Document Type: Article

References (45)

1. Yao, Z., S. L. Painter, W. C. Fanslow, B. Ulrich, B. M. Macduff, M. K. Spriggs, and R. J. Armitage. 1995. Human IL-17: a novel cytokine derived from T cells. J. Immunol. 155: 5483-5486.
2. Aggarwal, S., and A. L. Gurney. 2002. IL-17: prototype member of an emerging cytokine family. J. Leukocyte Biol. 71: 1-8.
3. Yao, Z., W. C. Fanslow, M. F. Seldin, A.-M. Rousseau, S. L. Painter, M. R. Comeau, J. I. Cohen, and M. K. Spriggs. 1995. Herpes saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 3: 811-821.
4. Fossiez, F., O. Djossou, P. Chomarat, L. Flores-Romo, S. Ait-Yahia, C. Maat, J.-J. Pin, P. Garrone, E. Garcia, S. Sealand, et al. 1995. T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J. Exp. Med. 183: 2593-2603.
5. Jovanovic, D. V., J. A. DiBattista, J. Martel-Pelletier, F. C. Jolicoeur, Y. He, M. Zhang, F. Mineau, and J.-P. Pelletier. 1998. IL-17 stimulates the production and expression of proinflammatory cytokines, IL-1β and TNF-α, by human macrophages. J. Immunol. 160: 3513-3521.
6. Schwarzenberger, P., W. Huang, P. Ye, P. Oliver, M. Mannuel, Z. Zhang, G. Bagby, S. Nelson, and J. K. Kolls. 2000. Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis. J. Immunol. 164: 4783-4789.
7. Antonysamy, M. A., W. C. Fanslow, F. Fu, W. Li, S. Qian, A. B. Troutt, and A. W. Thomson. 1999. Evidence for a role of IL-17 in organ allograft rejection: IL-17 promotes the functional differentiation of dendritic cell progenitors. J. Immunol. 162: 577-584.
8. Laan, M., Z. H. Cui, H. Hoshino, J. Lotvall, M. Sjöstrand, D. C. Gruenert, B. E. Skoogh, and A. Linden. 1999. Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways. J. Immunol. 162: 2347-2352.
9. Nakae, S., Y. Komiyama, A. Nambu, K. Sudo, M. Iwase, I. Homma, K. Sekikawa, M. Asano, and Y. Iwakura. 2002, Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 17: 375-387.
10. Schwandner, R., K. Yamaguchi, and Z. Cao. 2000. Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin-17 signal transduction. J. Exp. Med. 191: 1233-1240.
11. Awane, M., P. G. Andres, D. J. Li, and H. C. Reinecker. 1999. NF-κB-inducing kinase is a common mediator of IL-17-, TNF-α, and IL-1β-induced chemokine promoter activation in intestinal epithelial cells. J. Immunol. 162: 5337-5344.
12. Shalom-Barak, T., J. Quach, and M. Lotz. 1998. Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NF-κB. J. Biol. Chem. 273: 27467-27473.
13. Ye, P., F. H. Rodriguez, S. Kanaly, K. L. Stocking, J. Schurr, P. Schwarzenberger, P. Oliver, W. Huang, P. Zhang, J. Zhang, et al. 2001. Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defence. J. Exp. Med. 194: 519-527.
14. Hurst, S. D., T. Muchamuel, D. M. Gorman, J. M. Gilbert, T. Clifford, S. Kwan, S. Menon, B. Seymour, C. Jackson, T. T. Kung, et al. 2002. New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25. J. Immunol. 169: 443-453.
15. Fujino, S., A. Andoh, S. Bamba, A. Ogawa, K. Hata, Y. Araki, T. Bamba, and Y. Fujiyama. 2003. Increased expression of interleukin-17 in inflammatory bowel disease. Gut 52: 65-70.
16. Katz, Y., O. Nadiv, and Y. Beer. 2001. Interleukin-17 enhances tumor necrosis factor α-induced synthesis of interleukin 1, 6, and 8 in skin and synovial fibroblasts: a possible role as a "fine-tuning cytokine" in inflammation processes. Arthritis Rheum. 44: 2176-2184.
17. Toda, M., D. Y. Leung, S. Molet, M. Boguniewicz, R. Taha, P. Christodoulopoulos, T. Fukuda, J. A. Elias, and Q. A. Hamid. 2003. Polarized in vivo expression of IL-11 and IL-17 between acute and chronic skin lesions. J. Allergy Clin. Immunol. 111: 75-81.
18. Miossec, P. 2003. Interleukin-17 in rheumatoid arthritis: if T cells were to contribute to inflammation and destruction through synergy. Arthritis Rheum. 48: 594-601.
19. Kotake, S., N. Udagawa, N. Takahashi, K. Matsuzaki, K. Itoh, S. Ishiyama, S. Saito, K. Inoue, N. Kamatani, M. T. Gillespie, T. J. Martin, and T. Suda. 1999. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J. Clin. Invest. 103: 1345-1352.
20. Ziolkowska, M., A. Koc, G. Luszczykiewics, K. Ksiezopolska-Pietrzak, E. Klimczak, H. Chwalinska-Sadowska, and W. Maslinski. 2000. High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism. J. Immunol. 164:2832-2838.
21. Lock, C., G. Hermans, R. Pedotti, A. Brendolan, E. Schadt, H. Garren, A. Langer-Gould, S. Strober, B. Cannella, J. Allard, et al. 2002. Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat. Med. 8: 500-508.
22. Kurasawa, K., K. Hirose, H. Sano, H. Endo, H. Shinkai, Y. Nawata, K. Takabayashi, and I. Iwamoto. 2000. Increased interleukin-17 production in patients with systemic sclerosis. Arthritis Rheum. 43: 2455-2463.
23. Aarvak, T., M. Chabaud, P. Miossec, and J. B. Natvig. 1999. IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells. J. Immunol. 162: 1246-1251.
24. Albanesi, C., C. Scarponi, A. Cavani, M. Federici, F. Nasorri, and G. Girolomoni. 2000. Interleukin-17 is produced by both Th1 and Th2 lymphocytes, and modulates Interferon γ and interleukin-4-induced activation of human keratinocytes. J. Invest. Dermatol. 115: 81-87.
25. Infante-Duarte, C., H. F. Horton, M. C. Byrne, and T. Kamradt. 2000. Microbial lipopeptides induce the production of IL-17 in Th cells. J. Immunol. 165: 6107-6115.
26. Lubberts, E. 2003. The role of IL-17 and family members in the pathogenesis of arthritis. Curr. Opin. Invest. Drugs 4: 572-577.
27. Nakae, S., A. Nambu, K. Sudo, and Y. Iwakura. 2003. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J. Immunol. 171: 6173-6177.
28. Nakae, S., S. Saijo, R. Horai, K. Sudo, S. Mori, and Y. Iwakura. 2003. IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc. Natl. Acad. Sci. USA 100: 5986-5990.
29. Lubberts, E., L. A. B. Joosten, B. Oppers, L. van den Bersselaar, C. J. Coenen-de Roo, J. K. Kolls, P. Schwarrenberger, F. A. van de Loo, and W. B. van den Berg. 2001. IL-1-independent role of IL-17 in synovia) inflammation and joint destruction during collagen-induced arthritis. J. Immunol. 167: 1004-1013.
30. Lubberts, E., M. I. Koenders, B. Oppers-Walgreen, L. van den Bersselaar, C. J. J. Coenen-de Roo, L. A. B. Joosten, and W. B. van den Berg. 2004. Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion. Arthritis Rheum. 50: 650-659.
31. Van den Berg, W. B., L. A. B. Joosten, G. Kollias, and F. A. J. van de Loo. 1999. Role of tumour necrosis factor α in experimental arthritis: separate activity of interleukin 1β in chronicity and cartilage destruction. Ann. Rheum. Dis. 58(Suppl. I): 140-148.
32. Van den Broek, M. F., E. J. Hogervorst, M. C. van Bruggen, W. van Eden, R. van der Zee, and W. B. van den Berg. 1989. Protection against streptococcal cell wall-induced arthritis by pretreatment with the 65-kD mycobacterial heat shock protein. J. Exp. Med. 170: 449-466.
33. Forlow, S. B., J. R. Schurr, J. K. Kolls, G. J. Bagby, P. O. Schwarzenberger, and K. Ley. 2001. Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule-deficient mice. Blood 98: 3309-3314.
34. Lockhart, D. J., H. Dong, M. C. Byrne, M. T. Follettie, M. V. Gallo, M. S. Chee, M. Mittmann, C. Wang, M. Kobayashi, H. Horton, and E. L. Brown. 1996. Expression monitoring by hybridization to high-density oligonucleotide arrays. Nat. Biotechnol. 14: 1675-1680.
35. Van den Berg, W. B., L. A. B. Joosten, and L. B. A. van de Putte. 1984. Electrical charge of the antigen determines intraarticular handling and chronicity of arthritis in mice. J. Clin. Invest. 74: 1850-1859.
36. Lubberts, E., L. A. B. Joosten, M. Chabaud, L. van den Bersselaar, B. Oppers, C. J. J. Coenen-de Roo, C. D. Richards, P. Miossec, and W. B. van den Berg. 2000. IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion. J. Clin. Invest. 105: 1697-1710.
37. Joosten, L. A. B., M. I. Koenders, R. L. Smeets, M. Heuvelmans-Jacobs, M. M. Helsen, K. Takeda, S. Akira, E. Lubberts, F. A. van de Loo, and W. B. van den Berg. 2003. Toll-like receptor 2 pathway drives streptococcal cell wall-induced joint inflammation: critical role of myeloid differentiation factor 88. J. Immunol. 171: 6145-6153.
38. Ferretti, S., O. Bonneau, G. R. Dubois, C. E. Jones, and A. Trifilieff. 2003. IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger. J. Immunol. 170: 2106-2112.
39. Hoshino, H., M. Laan, M. Sjöstrand, J. Lötvall, B.-E. Skoogh, and A. Linden. 2000. Increased elastase and myeloperoxidase activity associated with neutrophil recruitment by IL-17 in airways in vivo. J. Allergy Clin. Immunol. 105: 143-149.
40. Chabaud, M., E. Lubberts, L. Joosten, W. van den Berg, and P. Miossec. 2001. IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis. Arthritis Res. 3: 168-177.
41. Bezooijen, R., H. C. Farih-Sips, S. E. Papapoulos, and C. W. Lowik. 1999. Interleukin-17: a new bone acting cytokine in vitro. J. Bone Min. Res. 14: 1513-1521.
42. Bush, K. A., K. M. Farmer, J. S. Walker, and B. W. Kirkham. 2002. Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor IgG1 Fc fusion protein. Arthritis Rheum. 46: 802-805.
43. Lubberts, E., L. van den Bersselaar, B. Oppers-Walgreen, P. Schwarzenberger, C. J. J. Coenen-de Roo, J. K. Kolls, L. A. B. Joosten, and W. B. van den Berg. 2003. IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the RANKL/OPG balance. J. Immunol. 170: 2655-2662.
44. Leeman, M. F., S. Curran, and G. L. Murray. 2002. The structure, regulation, and function of human matrix metalloproteinase-13. Crit. Rev. Biochem. Mol. Biol. 37: 149-166.
45. Rifas, L., and S. Arackal. 2003. T cells regulate the expression of matrix metalloproteinase in human osteoblasts via a dual mitogen-activated protein kinase mechanism. Arthritis Rheum. 48: 993-1001.