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Volumn 43, Issue 1, 2011, Pages 1-6

Genetic controls of th17 cell differentiation and plasticity

Author keywords

CD4 positive T lymphocytes; Cell differentiation; Cytokines; Th17 cells; Transcription factors

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; I KAPPA B; I KAPPA B ZETA; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 17; INTERLEUKIN 17F; PROTEIN BATF; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; SMAD3 PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 79251618802     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2011.43.1.007     Document Type: Article
Times cited : (49)

References (41)
  • 1
    • 34147138648 scopus 로고    scopus 로고
    • Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation
    • Akimzhanov AM, Yang XO, Dong C. Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation. J Biol Chem 2007;282:5969-72
    • (2007) J Biol Chem , vol.282 , pp. 5969-5972
    • Akimzhanov, A.M.1    Yang, X.O.2    Dong, C.3
  • 5
    • 42649115767 scopus 로고    scopus 로고
    • TH17 cells in development: An updated view of their molecular identity and genetic programming
    • Dong C. TH17 cells in development: an updated view of their molecular identity and genetic programming. Nat Rev Immunol 2008;8:337-48
    • (2008) Nat Rev Immunol , vol.8 , pp. 337-348
    • Dong, C.1
  • 6
    • 44449131480 scopus 로고    scopus 로고
    • Isoform-specific inhibition of RORα-mediated transcriptional activation by human FOXP3
    • Du J, Huang C, Zhou B, Ziegler SF. Isoform-specific inhibition of RORα-mediated transcriptional activation by human FOXP3. J Immunol 2008;180:4785-92
    • (2008) J Immunol , vol.180 , pp. 4785-4792
    • Du, J.1    Huang, C.2    Zhou, B.3    Ziegler, S.F.4
  • 7
    • 0141567438 scopus 로고    scopus 로고
    • The role of the nuclear hormone receptor RORγt in the development of lymph nodes and Peyer's patches
    • Eberl G, Littman DR. The role of the nuclear hormone receptor RORγt in the development of lymph nodes and Peyer's patches. Immunol Rev 2003;195:81-90
    • (2003) Immunol Rev , vol.195 , pp. 81-90
    • Eberl, G.1    Littman, D.R.2
  • 8
    • 23044466047 scopus 로고    scopus 로고
    • Specificity and versatility in TGF-β signaling through Smads
    • Feng XH , Derynck R. Specificity and versatility in TGF-β signaling through Smads. Annu Rev Cell Dev Biol 2005; 21:659-93
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 659-693
    • Feng, X.H.1    Derynck, R.2
  • 9
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005;6:1123-32
    • (2005) Nat Immunol , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6    Weaver, C.T.7
  • 10
    • 77958072084 scopus 로고    scopus 로고
    • Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis
    • 52ra72
    • Hueber W, Patel DD, Dryja T, Wright AM, Koroleva I, Bruin G, Antoni C, Draelos Z, Gold MH, Group tPS, Durez P, Tak PP, Gomez-Reino JJ, Group tRAS, Foster CS, Kim RY, Samson CM, Falk NS, Chu DS, Callanan D, Nguyen QD, Group tUS, Rose K, Haider A, Di Padova F. Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis. Sci Transl Med 2010; 2:52ra72
    • (2010) Uveitis. Sci Transl Med , vol.2
    • Hueber, W.1    Patel, D.D.2    Dryja, T.3    Wright, A.M.4    Koroleva, I.5    Bruin, G.6    Antoni, C.7    Draelos, Z.8    Gold, M.H.9
  • 11
  • 12
    • 8844279094 scopus 로고    scopus 로고
    • Recent advances in the mechanisms of action and physiological functions of the retinoid-related orphan receptors (RORs)
    • Jetten AM. Recent advances in the mechanisms of action and physiological functions of the retinoid-related orphan receptors (RORs). Curr Drug Targets Inflamm Allergy 2004; 3:395-412
    • (2004) Curr Drug Targets Inflamm Allergy , vol.3 , pp. 395-412
    • Jetten, A.M.1
  • 16
    • 77956546075 scopus 로고    scopus 로고
    • SMAD2 is essential for TGFβ-mediated Th17 cell generation
    • Malhotra N, Robertson E, Kang J. SMAD2 is essential for TGFβ-mediated Th17 cell generation. J Biol Chem 2010; 285:29044-8
    • (2010) J Biol Chem , vol.285 , pp. 29044-29048
    • Malhotra, N.1    Robertson, E.2    Kang, J.3
  • 19
    • 60549086638 scopus 로고    scopus 로고
    • Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells
    • Martin-Orozco N, Chung Y, Chang SH, Wang YH, Dong C. Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells. Eur J Immunol 2009a;39:216-24
    • (2009) Eur J Immunol , vol.39 , pp. 216-224
    • Martin-Orozco, N.1    Chung, Y.2    Chang, S.H.3    Wang, Y.H.4    Dong, C.5
  • 23
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145-73
    • (1989) Annu Rev Immunol , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 26
    • 64849103287 scopus 로고    scopus 로고
    • Cutting edge: In vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts
    • Nurieva R, Yang XO, Chung Y, Dong C. Cutting edge: in vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts. J Immunol 2009;182:2565-8
    • (2009) J Immunol , vol.182 , pp. 2565-2568
    • Nurieva, R.1    Yang, X.O.2    Chung, Y.3    Dong, C.4
  • 34
    • 58149214356 scopus 로고    scopus 로고
    • Sun H-w, Paul WE, O'Shea JJ, Zhao K.Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
    • Wei G, Wei L, Zhu J, Zang C, Hu-Li J, Yao Z, Cui K, Kanno Y, Roh T-Y, Watford WT, Schones DE, Peng W, Sun H-w, Paul WE, O'Shea JJ, Zhao K. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity 2009;30:155-67
    • (2009) Immunity , vol.30 , pp. 155-167
    • Wei, G.1    Wei, L.2    Zhu, J.3    Zang, C.4    Hu-Li, J.5    Yao, Z.6    Cui, K.7    Kanno, Y.8    Roh, T.-Y.9    Watford, W.T.10    Schones, D.E.11    Peng, W.12
  • 35
    • 34249799285 scopus 로고    scopus 로고
    • Cutting edge: Regulatory T cells induce CD4+CD25-Foxp3-T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-β
    • Xu L, Kitani A, Fuss I, Strober W. Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-β. J Immunol 2007;178:6725-9
    • (2007) J Immunol , vol.178 , pp. 6725-6729
    • Xu, L.1    Kitani, A.2    Fuss, I.3    Strober, W.4
  • 39
    • 54549100120 scopus 로고    scopus 로고
    • Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17-producing T cells
    • Zhang F, Meng G, Strober W. Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17-producing T cells. Nat Immunol 2008;9:1297-306
    • (2008) Nat Immunol , vol.9 , pp. 1297-1306
    • Zhang, F.1    Meng, G.2    Strober, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.