메뉴 건너뛰기




Volumn 6, Issue 4, 2012, Pages 322-333

Prion pathogenesis and secondary lymphoid organs (SLO): Tracking the SLO spread of prions to the brain

Author keywords

Follicular dendritic cells; M cells; Mononuclear phagocytes; Prion protein; Prion transmission; Secondary lymphoid tissue

Indexed keywords

GLYCOPROTEIN P 15095; PRION PROTEIN;

EID: 84866547992     PISSN: 19336896     EISSN: 1933690X     Source Type: Journal    
DOI: 10.4161/pri.20676     Document Type: Review
Times cited : (13)

References (124)
  • 1
    • 0020490156 scopus 로고
    • Identification of a protein that purifies with the scrapie prion
    • PMID:6815801
    • Bolton DC, McKinley MP, Prusiner SB. Identification of a protein that purifies with the scrapie prion. Science 1982; 218:1309-11; PMID:6815801; http://dx.doi.org/10.1126/science.6815801.
    • (1982) Science , vol.218 , pp. 1309-1311
    • Bolton, D.C.1    McKinley, M.P.2    Prusiner, S.B.3
  • 3
    • 78149392229 scopus 로고    scopus 로고
    • Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis
    • PMID:20966215
    • Eisele YS, Obermüller U, Heilbronner G, Baumann F, Kaeser SA, Wolburg H, et al. Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis. Science 2010; 330:980-2; PMID:20966215; http://dx.doi.org/10.1126/science.1194516.
    • (2010) Science , vol.330 , pp. 980-982
    • Eisele, Y.S.1    Obermüller, U.2    Heilbronner, G.3    Baumann, F.4    Kaeser, S.A.5    Wolburg, H.6
  • 4
    • 84866558750 scopus 로고    scopus 로고
    • Transmission of Synucleiopathies in the Enteric Nervous System of A53T Alpha-Synuclein Transgenic Mice
    • PMID:22355263
    • Lee HJ, Suk JE, Lee KW, Park SH, Blumbergs PC, Gai WP, et al. Transmission of Synucleiopathies in the Enteric Nervous System of A53T Alpha-Synuclein Transgenic Mice. Exp Neurobiol 2011; 20:181-8; PMID:22355263; http://dx.doi.org/10.5607/en.2011.20.4.181.
    • (2011) Exp Neurobiol , vol.20 , pp. 181-188
    • Lee, H.J.1    Suk, J.E.2    Lee, K.W.3    Park, S.H.4    Blumbergs, P.C.5    Gai, W.P.6
  • 5
    • 0038618854 scopus 로고    scopus 로고
    • Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility
    • PMID:12768004
    • Mabbott NA, Young J, McConnell I, Bruce ME. Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility. J Virol 2003; 77:6845-54; PMID:12768004; http://dx.doi.org/10.1128/JVI.77.12.6845-54.2003.
    • (2003) J Virol , vol.77 , pp. 6845-6854
    • Mabbott, N.A.1    Young, J.2    McConnell, I.3    Bruce, M.E.4
  • 6
    • 0037377727 scopus 로고    scopus 로고
    • Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes
    • PMID:12651603
    • Prinz M, Huber G, Macpherson AJS, Heppner FL, Glatzel M, Eugster HP, et al. Oral prion infection requires normal numbers of Peyer's patches but not of enteric lymphocytes. Am J Pathol 2003; 162:1103-11; PMID:12651603; http://dx.doi.org/10.1016/S0002-9440(10)63907-7.
    • (2003) Am J Pathol , vol.162 , pp. 1103-1111
    • Prinz, M.1    Huber, G.2    Macpherson, A.J.S.3    Heppner, F.L.4    Glatzel, M.5    Eugster, H.P.6
  • 7
    • 33947228815 scopus 로고    scopus 로고
    • Role of the GALT in scrapie agent neuroinvasion from the intestine
    • PMID:17339474
    • Glaysher BR, Mabbott NA. Role of the GALT in scrapie agent neuroinvasion from the intestine. J Immunol 2007; 178:3757-66; PMID:17339474.
    • (2007) J Immunol , vol.178 , pp. 3757-3766
    • Glaysher, B.R.1    Mabbott, N.A.2
  • 8
    • 0034536342 scopus 로고    scopus 로고
    • Early accumulation of PrP(Sc) in gut-associated lymphoid and nervous tissues of susceptible sheep from a Romanov flock with natural scrapie
    • PMID:11086143
    • Andréoletti O, Berthon P, Marc D, Sarradin P, Grosclaude J, van Keulen L, et al. Early accumulation of PrP(Sc) in gut-associated lymphoid and nervous tissues of susceptible sheep from a Romanov flock with natural scrapie. J Gen Virol 2000; 81:3115-26; PMID:11086143.
    • (2000) J Gen Virol , vol.81 , pp. 3115-3126
    • Andréoletti, O.1    Berthon, P.2    Marc, D.3    Sarradin, P.4    Grosclaude, J.5    Van Keulen, L.6
  • 10
    • 84855282475 scopus 로고    scopus 로고
    • Follicular dendritic cell-specific prion protein (PrP) expression alone is sufficient to sustain prion infection in the spleen
    • PMID:22144895
    • McCulloch L, Brown KL, Bradford BM, Hopkins J, Bailey M, Rajewsky K, et al. Follicular dendritic cell-specific prion protein (PrP) expression alone is sufficient to sustain prion infection in the spleen. PLoS Pathog 2011; 7:1002402; PMID:22144895; http://dx.doi.org/10.1371/journal.ppat.1002402.
    • (2011) PLoS Pathog , vol.7 , pp. 1002402
    • McCulloch, L.1    Brown, K.L.2    Bradford, B.M.3    Hopkins, J.4    Bailey, M.5    Rajewsky, K.6
  • 11
    • 0034891027 scopus 로고    scopus 로고
    • Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion
    • PMID:11498048
    • Glatzel M, Heppner FL, Albers KM, Aguzzi A. Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion. Neuron 2001; 31:25-34; PMID:11498048; http://dx.doi.org/10.1016/S0896-6273(01)00331-2.
    • (2001) Neuron , vol.31 , pp. 25-34
    • Glatzel, M.1    Heppner, F.L.2    Albers, K.M.3    Aguzzi, A.4
  • 12
    • 23444437972 scopus 로고    scopus 로고
    • Structure and function of the spleen
    • PMID:16056254
    • Mebius RE, Kraal G. Structure and function of the spleen. Nat Rev Immunol 2005; 5:606-16; PMID:16056254; http://dx.doi.org/10.1038/nri1669.
    • (2005) Nat Rev Immunol , vol.5 , pp. 606-616
    • Mebius, R.E.1    Kraal, G.2
  • 13
    • 57049131450 scopus 로고    scopus 로고
    • The conduit system of the lymph node
    • PMID:18824503
    • Roozendaal R, Mebius RE, Kraal G. The conduit system of the lymph node. Int Immunol 2008; 20:1483-7; PMID:18824503; http://dx.doi.org/10.1093/intimm/ dxn110.
    • (2008) Int Immunol , vol.20 , pp. 1483-1487
    • Roozendaal, R.1    Mebius, R.E.2    Kraal, G.3
  • 14
    • 75149175554 scopus 로고    scopus 로고
    • Stromal cell heterogeneity in lymphoid organs
    • PMID:19969504
    • Buettner M, Pabst R, Bode U. Stromal cell heterogeneity in lymphoid organs. Trends Immunol 2010; 31:80-6; PMID:19969504; http://dx.doi.org/10.1016/ j.it.2009.11.003.
    • (2010) Trends Immunol , vol.31 , pp. 80-86
    • Buettner, M.1    Pabst, R.2    Bode, U.3
  • 15
    • 70249085585 scopus 로고    scopus 로고
    • Stromal cell contributions to the homeostasis and functionality of the immune system
    • PMID:19644499
    • Mueller SN, Germain RN. Stromal cell contributions to the homeostasis and functionality of the immune system. Nat Rev Immunol 2009; 9:618-29; PMID:19644499.
    • (2009) Nat Rev Immunol , vol.9 , pp. 618-629
    • Mueller, S.N.1    Germain, R.N.2
  • 16
    • 0036518287 scopus 로고    scopus 로고
    • Mouse and human dendritic cell subtypes
    • PMID:11913066
    • Shortman K, Liu YJ. Mouse and human dendritic cell subtypes. Nat Rev Immunol 2002; 2:151-61; PMID:11913066; http://dx.doi.org/10.1038/nri746.
    • (2002) Nat Rev Immunol , vol.2 , pp. 151-161
    • Shortman, K.1    Liu, Y.J.2
  • 17
    • 0026719894 scopus 로고
    • Is the follicular dendritic cell a primarily stationary cell?
    • PMID:1526656
    • Imazeki N, Senoo A, Fuse Y. Is the follicular dendritic cell a primarily stationary cell? Immunology 1992; 76:508-10; PMID:1526656.
    • (1992) Immunology , vol.76 , pp. 508-510
    • Imazeki, N.1    Senoo, A.2    Fuse, Y.3
  • 18
    • 80052541140 scopus 로고    scopus 로고
    • Expression of mesenchyme-specific gene signatures by follicular dendritic cells: Insights from the meta-analysis of microarray data from multiple mouse cell populations
    • PMID:21635249
    • Mabbott NA, Kenneth Baillie J, Kobayashi A, Donaldson DS, Ohmori H, Yoon SO, et al. Expression of mesenchyme-specific gene signatures by follicular dendritic cells: insights from the meta-analysis of microarray data from multiple mouse cell populations. Immunology 2011; 133:482-98; PMID:21635249; http://dx.doi.org/10.1111/j.1365-2567.2011.03461.x.
    • (2011) Immunology , vol.133 , pp. 482-498
    • Mabbott, N.A.1    Kenneth Baillie, J.2    Kobayashi, A.3    Donaldson, D.S.4    Ohmori, H.5    Yoon, S.O.6
  • 19
    • 0032578283 scopus 로고    scopus 로고
    • Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease
    • PMID:9728989
    • Hilton DA, Fathers E, Edwards P, Ironside JW, Zajicek J. Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease. Lancet 1998; 352:703-4; PMID:9728989; http://dx.doi.org/10.1016/S0140- 6736(98)24035-9.
    • (1998) Lancet , vol.352 , pp. 703-704
    • Hilton, D.A.1    Fathers, E.2    Edwards, P.3    Ironside, J.W.4    Zajicek, J.5
  • 20
    • 0034099095 scopus 로고    scopus 로고
    • Tumor necrosis factoralpha-deficient, but not interleukin-6-deficient, mice resist peripheral infection with scrapie
    • PMID:10708451
    • Mabbott NA, Williams A, Farquhar CF, Pasparakis M, Kollias G, Bruce ME. Tumor necrosis factoralpha-deficient, but not interleukin-6-deficient, mice resist peripheral infection with scrapie. J Virol 2000; 74:3338-44; PMID:10708451; http://dx.doi.org/10.1128/JVI.74.7.3338-44.2000.
    • (2000) J Virol , vol.74 , pp. 3338-3344
    • Mabbott, N.A.1    Williams, A.2    Farquhar, C.F.3    Pasparakis, M.4    Kollias, G.5    Bruce, M.E.6
  • 21
    • 0037154263 scopus 로고    scopus 로고
    • Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells
    • PMID:11792852
    • Prinz M, Montrasio F, Klein MA, Schwarz P, Priller J, Odermatt B, et al. Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells. Proc Natl Acad Sci USA 2002; 99:919-24; PMID:11792852; http://dx.doi.org/10.1073/pnas.022626399.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 919-924
    • Prinz, M.1    Montrasio, F.2    Klein, M.A.3    Schwarz, P.4    Priller, J.5    Odermatt, B.6
  • 22
    • 0033930508 scopus 로고    scopus 로고
    • Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie
    • PMID:10888894
    • Mabbott NA, Mackay F, Minns F, Bruce ME. Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie. Nat Med 2000; 6:719-20; PMID:10888894; http://dx.doi.org/10.1038/77401.
    • (2000) Nat Med , vol.6 , pp. 719-720
    • Mabbott, N.A.1    Mackay, F.2    Minns, F.3    Bruce, M.E.4
  • 23
    • 0034686002 scopus 로고    scopus 로고
    • Impaired prion replication in spleens of mice lacking functional follicular dendritic cells
    • PMID:10818004
    • Montrasio F, Frigg R, Glatzel M, Klein MA, Mackay F, Aguzzi A, et al. Impaired prion replication in spleens of mice lacking functional follicular dendritic cells. Science 2000; 288:1257-9; PMID:10818004; http://dx.doi.org/10. 1126/science.288.5469.1257.
    • (2000) Science , vol.288 , pp. 1257-1259
    • Montrasio, F.1    Frigg, R.2    Glatzel, M.3    Klein, M.A.4    Mackay, F.5    Aguzzi, A.6
  • 24
    • 0027319326 scopus 로고
    • Mice devoid of PrP are resistant to scrapie
    • PMID:8100741
    • Büeler H, Aguzzi A, Sailer A, Greiner RA, Autenried P, Aguet M, et al. Mice devoid of PrP are resistant to scrapie. Cell 1993; 73:1339-47; PMID:8100741; http://dx.doi.org/10.1016/0092-8674(93)90360-3.
    • (1993) Cell , vol.73 , pp. 1339-1347
    • Büeler, H.1    Aguzzi, A.2    Sailer, A.3    Greiner, R.A.4    Autenried, P.5    Aguet, M.6
  • 25
    • 0028343093 scopus 로고
    • No propagation of prions in mice devoid of PrP
    • PMID:7912659
    • Sailer A, Büeler H, Fischer M, Aguzzi A, Weissmann C. No propagation of prions in mice devoid of PrP. Cell 1994; 77:967-8; PMID:7912659; http://dx.doi.org/10.1016/0092-8674(94)90436-7.
    • (1994) Cell , vol.77 , pp. 967-968
    • Sailer, A.1    Büeler, H.2    Fischer, M.3    Aguzzi, A.4    Weissmann, C.5
  • 26
    • 0032746253 scopus 로고    scopus 로고
    • Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells
    • PMID:10545999
    • Brown KL, Stewart K, Ritchie DL, Mabbott NA, Williams A, Fraser H, et al. Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells. Nat Med 1999; 5:1308-12; PMID:10545999; http://dx.doi.org/10.1038/15264.
    • (1999) Nat Med , vol.5 , pp. 1308-1312
    • Brown, K.L.1    Stewart, K.2    Ritchie, D.L.3    Mabbott, N.A.4    Williams, A.5    Fraser, H.6
  • 27
    • 0031759918 scopus 로고    scopus 로고
    • PrP expression in B lymphocytes is not required for prion neuroinvasion
    • PMID:9846583
    • Klein MA, Frigg R, Raeber AJ, Flechsig E, Hegyi I, Zinkernagel RM, et al. PrP expression in B lymphocytes is not required for prion neuroinvasion. Nat Med 1998; 4:1429-33; PMID:9846583; http://dx.doi.org/10.1038/4022.
    • (1998) Nat Med , vol.4 , pp. 1429-1433
    • Klein, M.A.1    Frigg, R.2    Raeber, A.J.3    Flechsig, E.4    Hegyi, I.5    Zinkernagel, R.M.6
  • 28
    • 57449112742 scopus 로고    scopus 로고
    • Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas
    • PMID:19100703
    • Heikenwalder M, Kurrer MO, Margalith I, Kranich J, Zeller N, Haybaeck J, et al. Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas. Immunity 2008; 29:998-1008; PMID:19100703; http://dx.doi.org/10. 1016/j.immuni.2008.10.014.
    • (2008) Immunity , vol.29 , pp. 998-1008
    • Heikenwalder, M.1    Kurrer, M.O.2    Margalith, I.3    Kranich, J.4    Zeller, N.5    Haybaeck, J.6
  • 29
    • 0032536532 scopus 로고    scopus 로고
    • Crucial role of tumor necrosis factor receptor 1 expression on nonhematopoietic cells for B cell localization within the splenic white pulp
    • PMID:9463397
    • Tkachuk M, Bolliger S, Ryffel B, Pluschke G, Banks TA, Herren S, et al. Crucial role of tumor necrosis factor receptor 1 expression on nonhematopoietic cells for B cell localization within the splenic white pulp. J Exp Med 1998; 187:469-77; PMID:9463397; http://dx.doi.org/10.1084/jem.187.4.469.
    • (1998) J Exp Med , vol.187 , pp. 469-477
    • Tkachuk, M.1    Bolliger, S.2    Ryffel, B.3    Pluschke, G.4    Banks, T.A.5    Herren, S.6
  • 30
    • 0031914415 scopus 로고    scopus 로고
    • Follicular dendritic cell (FDC) precursors in primary lymphoid tissues
    • PMID:9570519
    • Kapasi ZF, Qin D, Kerr WG, Kosco-Vilbois MH, Shultz LD, Tew JG, et al. Follicular dendritic cell (FDC) precursors in primary lymphoid tissues. J Immunol 1998; 160:1078-84; PMID:9570519.
    • (1998) J Immunol , vol.160 , pp. 1078-1084
    • Kapasi, Z.F.1    Qin, D.2    Kerr, W.G.3    Kosco-Vilbois, M.H.4    Shultz, L.D.5    Tew, J.G.6
  • 31
    • 0034254524 scopus 로고    scopus 로고
    • Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface
    • PMID:10903724
    • Denzer K, van Eijk M, Kleijmeer MJ, Jakobson E, de Groot C, Geuze HJ. Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface. J Immunol 2000; 165:1259-65; PMID:10903724.
    • (2000) J Immunol , vol.165 , pp. 1259-1265
    • Denzer, K.1    Van Eijk, M.2    Kleijmeer, M.J.3    Jakobson, E.4    De Groot, C.5    Geuze, H.J.6
  • 32
    • 3042788972 scopus 로고    scopus 로고
    • Cells release prions in association with exosomes
    • PMID:15210972
    • Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, et al. Cells release prions in association with exosomes. Proc Natl Acad Sci USA 2004; 101:9683-8; PMID:15210972; http://dx.doi.org/10.1073/pnas.0308413101.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 9683-9688
    • Fevrier, B.1    Vilette, D.2    Archer, F.3    Loew, D.4    Faigle, W.5    Vidal, M.6
  • 33
    • 84855290942 scopus 로고    scopus 로고
    • Prion uptake in the gut: Identification of the first uptake and replication sites
    • PMID:22216002
    • Kujala P, Raymond CR, Romeijn M, Godsave SF, van Kasteren SI, Wille H, et al. Prion uptake in the gut: identification of the first uptake and replication sites. PLoS Pathog 2011; 7:1002449; PMID:22216002; http://dx.doi.org/10.1371/ journal.ppat.1002449.
    • (2011) PLoS Pathog , vol.7 , pp. 1002449
    • Kujala, P.1    Raymond, C.R.2    Romeijn, M.3    Godsave, S.F.4    Van Kasteren, S.I.5    Wille, H.6
  • 34
    • 84855952265 scopus 로고    scopus 로고
    • The effects of host age on the transport of complement-bound complexes to the spleen and the pathogenesis of intravenous scrapie infection
    • PMID:22031932
    • Brown KL, Gossner A, Mok S, Mabbott NA. The effects of host age on the transport of complement-bound complexes to the spleen and the pathogenesis of intravenous scrapie infection. J Virol 2012; 86:25-35; PMID:22031932; http://dx.doi.org/10.1128/JVI.05581-11.
    • (2012) J Virol , vol.86 , pp. 25-35
    • Brown, K.L.1    Gossner, A.2    Mok, S.3    Mabbott, N.A.4
  • 35
    • 0036318879 scopus 로고    scopus 로고
    • The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues
    • PMID:12115608
    • Taylor PR, Pickering MC, Kosco-Vilbois MH, Walport MJ, Botto M, Gordon S, et al. The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues. Eur J Immunol 2002; 32:1888-96; PMID:12115608; http://dx.doi.org/10.1002/1521-4141(200207)32: 7〈1883::AIDIMMU1888〉3.0.CO;2-8.
    • (2002) Eur J Immunol , vol.32 , pp. 1888-1896
    • Taylor, P.R.1    Pickering, M.C.2    Kosco-Vilbois, M.H.3    Walport, M.J.4    Botto, M.5    Gordon, S.6
  • 37
    • 0035053039 scopus 로고    scopus 로고
    • Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie
    • PMID:11283677
    • Mabbott NA, Bruce ME, Botto M, Walport MJ, Pepys MB. Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie. Nat Med 2001; 7:485-7; PMID:11283677; http://dx.doi.org/10. 1038/86562.
    • (2001) Nat Med , vol.7 , pp. 485-487
    • Mabbott, N.A.1    Bruce, M.E.2    Botto, M.3    Walport, M.J.4    Pepys, M.B.5
  • 38
    • 4444291008 scopus 로고    scopus 로고
    • Complement component C5 is not involved in scrapie pathogenesis
    • PMID:15568618
    • Mabbott NA, Bruce ME. Complement component C5 is not involved in scrapie pathogenesis. Immunobiology 2004; 209:545-9; PMID:15568618; http://dx.doi.org/ 10.1016/j.imbio.2004.06.003.
    • (2004) Immunobiology , vol.209 , pp. 545-549
    • Mabbott, N.A.1    Bruce, M.E.2
  • 39
    • 38449119141 scopus 로고    scopus 로고
    • Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis
    • PMID:17947689
    • Zabel MD, Heikenwalder M, Prinz M, Arrighi I, Schwarz P, Kranich J, et al. Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis. J Immunol 2007; 179:6144-52; PMID:17947689.
    • (2007) J Immunol , vol.179 , pp. 6144-6152
    • Zabel, M.D.1    Heikenwalder, M.2    Prinz, M.3    Arrighi, I.4    Schwarz, P.5    Kranich, J.6
  • 40
    • 30444457243 scopus 로고    scopus 로고
    • FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses
    • PMID:16413924
    • Victoratos P, Lagnel J, Tzima S, Alimzhanov MB, Rajewsky K, Pasparakis M, et al. FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses. Immunity 2006; 24:65-77; PMID:16413924; http://dx.doi.org/10.1016/j.immuni.2005.11.013.
    • (2006) Immunity , vol.24 , pp. 65-77
    • Victoratos, P.1    Lagnel, J.2    Tzima, S.3    Alimzhanov, M.B.4    Rajewsky, K.5    Pasparakis, M.6
  • 41
    • 0030610087 scopus 로고    scopus 로고
    • Lymphotoxin-α (LTalpha) supports development of splenic follicular structure that is required for IgG responses
    • PMID:9182683
    • Fu YX, Molina H, Matsumoto M, Huang G, Min J, Chaplin DD. Lymphotoxin-α (LTalpha) supports development of splenic follicular structure that is required for IgG responses. J Exp Med 1997; 185:2111-20; PMID:9182683; http://dx.doi.org/10.1084/jem.185.12.2111.
    • (1997) J Exp Med , vol.185 , pp. 2111-2120
    • Fu, Y.X.1    Molina, H.2    Matsumoto, M.3    Huang, G.4    Min, J.5    Chaplin, D.D.6
  • 42
    • 0032489920 scopus 로고    scopus 로고
    • B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin α-dependent fashion
    • PMID:9529317
    • Fu YX, Huang G, Wang Y, Chaplin DD. B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin α-dependent fashion. J Exp Med 1998; 187:1009-18; PMID:9529317; http://dx.doi.org/10.1084/jem.187.7. 1009.
    • (1998) J Exp Med , vol.187 , pp. 1009-1018
    • Fu, Y.X.1    Huang, G.2    Wang, Y.3    Chaplin, D.D.4
  • 43
    • 0033521542 scopus 로고    scopus 로고
    • Mature follicular dendritic cell networks depend on expression of lymphotoxin β receptor by radioresistant stromal cells and of lymphotoxin β and tumor necrosis factor by B cells
    • PMID:9874572
    • Endres R, Alimzhanov MB, Plitz T, Fütterer A, Kosco-Vilbois MH, Nedospasov SA, et al. Mature follicular dendritic cell networks depend on expression of lymphotoxin β receptor by radioresistant stromal cells and of lymphotoxin β and tumor necrosis factor by B cells. J Exp Med 1999; 189:159-68; PMID:9874572; http://dx.doi.org/10.1084/jem.189.1.159.
    • (1999) J Exp Med , vol.189 , pp. 159-168
    • Endres, R.1    Alimzhanov, M.B.2    Plitz, T.3    Fütterer, A.4    Kosco-Vilbois, M.H.5    Nedospasov, S.A.6
  • 44
    • 0034163409 scopus 로고    scopus 로고
    • Lymphotoxin-α-dependent spleen microenvironment supports the generation of memory B cells and is required for their subsequent antigen-induced activation
    • PMID:10679088
    • Fu YX, Huang G, Wang Y, Chaplin DD. Lymphotoxin-α-dependent spleen microenvironment supports the generation of memory B cells and is required for their subsequent antigen-induced activation. J Immunol 2000; 164:2508-14; PMID:10679088.
    • (2000) J Immunol , vol.164 , pp. 2508-2514
    • Fu, Y.X.1    Huang, G.2    Wang, Y.3    Chaplin, D.D.4
  • 45
    • 17844371994 scopus 로고    scopus 로고
    • The influence of immune complex-bearing follicular dendritic cells on the IgM response, Ig class switching and production of high affinity IgG
    • PMID:15843533
    • Aydar Y, Sukumar S, Szakal AK, Tew JG. The influence of immune complex-bearing follicular dendritic cells on the IgM response, Ig class switching and production of high affinity IgG. J Immunol 2005; 174:5358-66; PMID:15843533.
    • (2005) J Immunol , vol.174 , pp. 5358-5366
    • Aydar, Y.1    Sukumar, S.2    Szakal, A.K.3    Tew, J.G.4
  • 46
    • 77949517161 scopus 로고    scopus 로고
    • Scrapie affects the maturation cycle and immune complex trapping by follicular dendritic cells in mice
    • PMID:19997557
    • McGovern G, Mabbott NA, Jeffrey M. Scrapie affects the maturation cycle and immune complex trapping by follicular dendritic cells in mice. PLoS One 2009; 4:8186; PMID:19997557; http://dx.doi.org/10.1371/journal.pone.0008186.
    • (2009) PLoS One , vol.4 , pp. 8186
    • McGovern, G.1    Mabbott, N.A.2    Jeffrey, M.3
  • 48
    • 33846551867 scopus 로고    scopus 로고
    • The spread of prions through the body in naturally acquired transmissible spongiform encephalopathies
    • PMID:17288548
    • Beekes M, McBride PA. The spread of prions through the body in naturally acquired transmissible spongiform encephalopathies. FEBS J 2007; 274:588-605; PMID:17288548; http://dx.doi.org/10.1111/j.1742-4658.2007.05631.x.
    • (2007) FEBS J , vol.274 , pp. 588-605
    • Beekes, M.1    McBride, P.A.2
  • 49
    • 0242499506 scopus 로고    scopus 로고
    • Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion
    • PMID:14562059
    • Prinz M, Heikenwalder M, Junt T, Schwarz P, Glatzel M, Heppner FL, et al. Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion. Nature 2003; 425:957-62; PMID:14562059; http://dx.doi.org/10. 1038/nature02072.
    • (2003) Nature , vol.425 , pp. 957-962
    • Prinz, M.1    Heikenwalder, M.2    Junt, T.3    Schwarz, P.4    Glatzel, M.5    Heppner, F.L.6
  • 50
    • 0034798246 scopus 로고    scopus 로고
    • Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie
    • PMID:11544275
    • Aucouturier P, Geissmann F, Damotte D, Saborio GP, Meeker HC, Kascsak R, et al. Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie. J Clin Invest 2001; 108:703-8; PMID:11544275.
    • (2001) J Clin Invest , vol.108 , pp. 703-708
    • Aucouturier, P.1    Geissmann, F.2    Damotte, D.3    Saborio, G.P.4    Meeker, H.C.5    Kascsak, R.6
  • 51
    • 61849178720 scopus 로고    scopus 로고
    • Prions hijack tunnelling nanotubes for intercellular spread
    • PMID:19198598
    • Gousset K, Schiff E, Langevin C, Marijanovic Z, Caputo A, Browman DT, et al. Prions hijack tunnelling nanotubes for intercellular spread. Nat Cell Biol 2009; 11:328-36; PMID:19198598; http://dx.doi.org/10.1038/ncb1841.
    • (2009) Nat Cell Biol , vol.11 , pp. 328-336
    • Gousset, K.1    Schiff, E.2    Langevin, C.3    Marijanovic, Z.4    Caputo, A.5    Browman, D.T.6
  • 52
    • 77957923715 scopus 로고    scopus 로고
    • Characterization of the role of dendritic cells in prion transfer to primary neurons
    • PMID:20670217
    • Langevin C, Gousset K, Costanzo M, Richard-Le Goff O, Zurzolo C. Characterization of the role of dendritic cells in prion transfer to primary neurons. Biochem J 2010; 431:189-98; PMID:20670217; http://dx.doi.org/10.1042/ BJ20100698.
    • (2010) Biochem J , vol.431 , pp. 189-198
    • Langevin, C.1    Gousset, K.2    Costanzo, M.3    Richard-Le Goff, O.4    Zurzolo, C.5
  • 53
    • 34347236155 scopus 로고    scopus 로고
    • Assessing the involvement of migratory dendritic cells in the transfer of the scrapie agent from the immune to peripheral nervous systems
    • PMID:17561271
    • Raymond CR, Mabbott NA. Assessing the involvement of migratory dendritic cells in the transfer of the scrapie agent from the immune to peripheral nervous systems. J Neuroimmunol 2007; 187:114-25; PMID:17561271; http://dx.doi.org/10. 1016/j.jneuroim.2007.05.006.
    • (2007) J Neuroimmunol , vol.187 , pp. 114-125
    • Raymond, C.R.1    Mabbott, N.A.2
  • 54
    • 77950491661 scopus 로고    scopus 로고
    • RANKL is necessary and sufficient to initiate development of antigen-sampling M cells in the intestinal epithelium
    • PMID:19828638
    • Knoop KA, Kumar N, Butler BR, Sakthivel SK, Taylor RT, Nochi T, et al. RANKL is necessary and sufficient to initiate development of antigen-sampling M cells in the intestinal epithelium. J Immunol 2009; 183:5738-47; PMID:19828638; http://dx.doi.org/10.4049/jimmunol.0901563.
    • (2009) J Immunol , vol.183 , pp. 5738-5747
    • Knoop, K.A.1    Kumar, N.2    Butler, B.R.3    Sakthivel, S.K.4    Taylor, R.T.5    Nochi, T.6
  • 55
    • 70349919678 scopus 로고    scopus 로고
    • New approach for m-cell-specific molecules screening by comprehensive transcriptome analysis
    • PMID:19675110
    • Nakato G, Fukuda S, Hase K, Goitsuka R, Cooper MD, Ohno H. New approach for m-cell-specific molecules screening by comprehensive transcriptome analysis. DNA Res 2009; 16:227-35; PMID:19675110; http://dx.doi.org/10.1093/dnares/ dsp013.
    • (2009) DNA Res , vol.16 , pp. 227-235
    • Nakato, G.1    Fukuda, S.2    Hase, K.3    Goitsuka, R.4    Cooper, M.D.5    Ohno, H.6
  • 56
    • 0022894823 scopus 로고
    • Cytopathogenic effect of Salmonella typhi GIFU 10,007 on M cells of murine ileal Peyer's patches in ligated ileal loops: An ultrastructural study
    • PMID:3553868
    • Kohbata S, Yokoyama H, Yabuuchi E. Cytopathogenic effect of Salmonella typhi GIFU 10,007 on M cells of murine ileal Peyer's patches in ligated ileal loops: an ultrastructural study. Microbiol Immunol 1986; 30:1225-37; PMID:3553868.
    • (1986) Microbiol Immunol , vol.30 , pp. 1225-1237
    • Kohbata, S.1    Yokoyama, H.2    Yabuuchi, E.3
  • 58
    • 0028214086 scopus 로고
    • Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches
    • PMID:8006579
    • Jones BD, Ghori N, Falkow S. Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches. J Exp Med 1994; 180:15-23; PMID:8006579; http://dx.doi.org/10.1084/jem.180.1.15.
    • (1994) J Exp Med , vol.180 , pp. 15-23
    • Jones, B.D.1    Ghori, N.2    Falkow, S.3
  • 59
    • 0030576516 scopus 로고    scopus 로고
    • Epithelial M cells: Gateways for mucosal infection and immunization
    • PMID:8756716
    • Neutra MR, Frey A, Kraehenbuhl JP. Epithelial M cells: gateways for mucosal infection and immunization. Cell 1996; 86:345-8; PMID:8756716; http://dx.doi.org/10.1016/S0092-8674(00)80106-3.
    • (1996) Cell , vol.86 , pp. 345-348
    • Neutra, M.R.1    Frey, A.2    Kraehenbuhl, J.P.3
  • 60
    • 0032792638 scopus 로고    scopus 로고
    • M cells as ports of entry for enteroinvasive pathogens: Mechanisms of interaction, consequences for the disease process
    • PMID:10381865
    • Sansonetti PJ, Phalipon A. M cells as ports of entry for enteroinvasive pathogens: mechanisms of interaction, consequences for the disease process. Semin Immunol 1999; 11:193-203; PMID:10381865; http://dx.doi.org/10.1006/smim. 1999.0175.
    • (1999) Semin Immunol , vol.11 , pp. 193-203
    • Sansonetti, P.J.1    Phalipon, A.2
  • 61
    • 80052869514 scopus 로고    scopus 로고
    • Orally administered prion protein is incorporated by m cells and spreads into lymphoid tissues with macrophages in prion protein knockout mice
    • PMID:21763679
    • Takakura I, Miyazawa K, Kanaya T, Itani W, Watanabe K, Ohwada S, et al. Orally administered prion protein is incorporated by m cells and spreads into lymphoid tissues with macrophages in prion protein knockout mice. Am J Pathol 2011; 179:1301-9; PMID:21763679; http://dx.doi.org/10.1016/j.ajpath.2011.05.058.
    • (2011) Am J Pathol , vol.179 , pp. 1301-1309
    • Takakura, I.1    Miyazawa, K.2    Kanaya, T.3    Itani, W.4    Watanabe, K.5    Ohwada, S.6
  • 62
    • 78650393262 scopus 로고    scopus 로고
    • Murine cecal patch M cells transport infectious prions in vivo
    • PMID:21050122
    • Foster N, Macpherson GG. Murine cecal patch M cells transport infectious prions in vivo. J Infect Dis 2010; 202:1916-9; PMID:21050122; http://dx.doi.org/10.1086/657415.
    • (2010) J Infect Dis , vol.202 , pp. 1916-1919
    • Foster, N.1    Macpherson, G.G.2
  • 64
    • 33646000633 scopus 로고    scopus 로고
    • Transportation of prion protein across the intestinal mucosa of scrapie-susceptible and scrapie-resistant sheep
    • PMID:16575799
    • Jeffrey M, González L, Espenes A, Press CM, Martin S, Chaplin M, et al. Transportation of prion protein across the intestinal mucosa of scrapie-susceptible and scrapie-resistant sheep. J Pathol 2006; 209:4-14; PMID:16575799; http://dx.doi.org/10.1002/path.1962.
    • (2006) J Pathol , vol.209 , pp. 4-14
    • Jeffrey, M.1    González, L.2    Espenes, A.3    Press, C.M.4    Martin, S.5    Chaplin, M.6
  • 65
    • 10644241804 scopus 로고    scopus 로고
    • Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: Implications for species barrier in prion uptake from the intestine
    • PMID:15601934
    • Mishra RS, Basu S, Gu Y, Luo X, Zou WQ, Mishra R, et al. Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: implications for species barrier in prion uptake from the intestine. J Neurosci 2004; 24:11280-90; PMID:15601934; http://dx.doi.org/ 10.1523/JNEUROSCI.2864-04.2004.
    • (2004) J Neurosci , vol.24 , pp. 11280-11290
    • Mishra, R.S.1    Basu, S.2    Gu, Y.3    Luo, X.4    Zou, W.Q.5    Mishra, R.6
  • 67
    • 70449653428 scopus 로고    scopus 로고
    • Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response
    • PMID:19907495
    • Hase K, Kawano K, Nochi T, Pontes GS, Fukuda S, Ebisawa M, et al. Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response. Nature 2009; 462:226-30; PMID:19907495; http://dx.doi.org/10.1038/ nature08529.
    • (2009) Nature , vol.462 , pp. 226-230
    • Hase, K.1    Kawano, K.2    Nochi, T.3    Pontes, G.S.4    Fukuda, S.5    Ebisawa, M.6
  • 68
    • 0037477612 scopus 로고    scopus 로고
    • Cellular prion protein promotes Brucella infection into macrophages
    • PMID:12847134
    • Watarai M, Kim S, Erdenebaatar J, Makino SI, Horiuchi M, Shirahata T, et al. Cellular prion protein promotes Brucella infection into macrophages. J Exp Med 2003; 198:5-17; PMID:12847134; http://dx.doi.org/10.1084/jem.20021980.
    • (2003) J Exp Med , vol.198 , pp. 5-17
    • Watarai, M.1    Kim, S.2    Erdenebaatar, J.3    Makino, S.I.4    Horiuchi, M.5    Shirahata, T.6
  • 69
    • 80053277573 scopus 로고    scopus 로고
    • Defining the anatomical localisation of subsets of the murine mononuclear phagocyte system using integrin alpha X (Itgax, CD11c) and colony stimulating factor 1 receptor (Csf1r, CD115) expression fails to discriminate dendritic cells from macrophages
    • PMID:21885153
    • Bradford BM, Sester DP, Hume DA, Mabbott NA. Defining the anatomical localisation of subsets of the murine mononuclear phagocyte system using integrin alpha X (Itgax, CD11c) and colony stimulating factor 1 receptor (Csf1r, CD115) expression fails to discriminate dendritic cells from macrophages. Immunobiology 2011; 216:1228-37; PMID:21885153; http://dx.doi.org/10.1016/j. imbio.2011.08.006.
    • (2011) Immunobiology , vol.216 , pp. 1228-1237
    • Bradford, B.M.1    Sester, D.P.2    Hume, D.A.3    Mabbott, N.A.4
  • 71
    • 0027410872 scopus 로고
    • Antigen acquisition by dendritic cells: Intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivo
    • PMID:8478609
    • Liu LM, MacPherson GG. Antigen acquisition by dendritic cells: intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivo. J Exp Med 1993; 177:1299-307; PMID:8478609; http://dx.doi.org/10.1084/ jem.177.5.1299.
    • (1993) J Exp Med , vol.177 , pp. 1299-1307
    • Liu, L.M.1    MacPherson, G.G.2
  • 72
    • 14844340568 scopus 로고    scopus 로고
    • Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate
    • PMID:15761154
    • Delamarre L, Pack M, Chang H, Mellman I, Trombetta ES. Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science 2005; 307:1630-4; PMID:15761154; http://dx.doi.org/10.1126/science. 1108003.
    • (2005) Science , vol.307 , pp. 1630-1634
    • Delamarre, L.1    Pack, M.2    Chang, H.3    Mellman, I.4    Trombetta, E.S.5
  • 73
    • 27744576801 scopus 로고    scopus 로고
    • Cell surface recycling of internalized antigen permits dendritic cell priming of B cells
    • PMID:16286018
    • Bergtold A, Desai DD, Gavhane A, Clynes R. Cell surface recycling of internalized antigen permits dendritic cell priming of B cells. Immunity 2005; 23:503-14; PMID:16286018; http://dx.doi.org/10.1016/j.immuni.2005.09.013.
    • (2005) Immunity , vol.23 , pp. 503-514
    • Bergtold, A.1    Desai, D.D.2    Gavhane, A.3    Clynes, R.4
  • 74
    • 0032145432 scopus 로고    scopus 로고
    • Dendritic cells interact directly with naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent response
    • PMID:9686593
    • Wykes M, Pombo A, Jenkins C, MacPherson GG. Dendritic cells interact directly with naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent response. J Immunol 1998; 161:1313-9; PMID:9686593.
    • (1998) J Immunol , vol.161 , pp. 1313-1319
    • Wykes, M.1    Pombo, A.2    Jenkins, C.3    MacPherson, G.G.4
  • 75
    • 1542618118 scopus 로고    scopus 로고
    • Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria
    • PMID:15016999
    • Macpherson AJ, Uhr T. Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science 2004; 303:1662-5; PMID:15016999; http://dx.doi.org/10.1126/science.1091334.
    • (2004) Science , vol.303 , pp. 1662-1665
    • Macpherson, A.J.1    Uhr, T.2
  • 77
    • 38849196274 scopus 로고    scopus 로고
    • + cells impairs scrapie agent neuroinvasion from the intestine
    • PMID:18025222
    • + cells impairs scrapie agent neuroinvasion from the intestine. J Immunol 2007; 179:7758-66; PMID:18025222.
    • (2007) J Immunol , vol.179 , pp. 7758-7766
    • Raymond, C.R.1    Aucouturier, P.2    Mabbott, N.A.3
  • 78
    • 50149085067 scopus 로고    scopus 로고
    • + dendritic cells delays lymphoinvasion after intraperitonal scrapie infection
    • PMID:18579603
    • + dendritic cells delays lymphoinvasion after intraperitonal scrapie infection. J Virol 2008; 82:8933-6; PMID:18579603; http://dx.doi.org/10.1128/JVI.02440-07.
    • (2008) J Virol , vol.82 , pp. 8933-8936
    • Cordier-Dirikoc, S.1    Chabry, J.2
  • 79
    • 84860892468 scopus 로고    scopus 로고
    • Determining the role of mononuclear phagocytes in prion neuroinvasion from the skin
    • PMID:22389312
    • Wathne GJ, Kissenpfennig A, Malissen B, Zurzolo C, Mabbott NA. Determining the role of mononuclear phagocytes in prion neuroinvasion from the skin. J Leukoc Biol 2012; 91:817-28; PMID:22389312; http://dx.doi.org/10.1189/ jlb.1211633.
    • (2012) J Leukoc Biol , vol.91 , pp. 817-828
    • Wathne, G.J.1    Kissenpfennig, A.2    Malissen, B.3    Zurzolo, C.4    Mabbott, N.A.5
  • 80
    • 77955412944 scopus 로고    scopus 로고
    • Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations
    • PMID:20580463
    • Mabbott NA, Kenneth Baillie JC, Hume DA, Freeman TC. Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations. Immunobiology 2010; 215:724-36; PMID:20580463; http://dx.doi.org/10.1016/j. imbio.2010.05.012.
    • (2010) Immunobiology , vol.215 , pp. 724-736
    • Mabbott, N.A.1    Kenneth Baillie, J.C.2    Hume, D.A.3    Freeman, T.C.4
  • 81
    • 57249097160 scopus 로고    scopus 로고
    • Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: A potential mechanism for intercellular HIV trafficking
    • PMID:18835599
    • Eugenin EA, Gaskill PJ, Berman JW. Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: a potential mechanism for intercellular HIV trafficking. Cell Immunol 2009; 254:142-8; PMID:18835599; http://dx.doi.org/10. 1016/j.cellimm.2008.08.005.
    • (2009) Cell Immunol , vol.254 , pp. 142-148
    • Eugenin, E.A.1    Gaskill, P.J.2    Berman, J.W.3
  • 82
    • 69049119032 scopus 로고    scopus 로고
    • HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits
    • PMID:19648924
    • Xu W, Santini PA, Sullivan JS, He B, Shan M, Ball SC, et al. HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits. Nat Immunol 2009; 10:1008-17; PMID:19648924; http://dx.doi.org/10.1038/ni.1753.
    • (2009) Nat Immunol , vol.10 , pp. 1008-1017
    • Xu, W.1    Santini, P.A.2    Sullivan, J.S.3    He, B.4    Shan, M.5    Ball, S.C.6
  • 83
    • 73349111312 scopus 로고    scopus 로고
    • M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex
    • PMID:19935652
    • Hase K, Kimura S, Takatsu H, Ohmae M, Kawano S, Kitamura H, et al. M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex. Nat Cell Biol 2009; 11:1427-32; PMID:19935652; http://dx.doi.org/10. 1038/ncb1990.
    • (2009) Nat Cell Biol , vol.11 , pp. 1427-1432
    • Hase, K.1    Kimura, S.2    Takatsu, H.3    Ohmae, M.4    Kawano, S.5    Kitamura, H.6
  • 84
    • 81455131800 scopus 로고    scopus 로고
    • Convergent and divergent development among M cell lineages in mouse mucosal epithelium
    • PMID:21984701
    • Wang J, Gusti V, Saraswati A, Lo DD. Convergent and divergent development among M cell lineages in mouse mucosal epithelium. J Immunol 2011; 187:5277-85; PMID:21984701; http://dx.doi.org/10.4049/jimmunol.1102077.
    • (2011) J Immunol , vol.187 , pp. 5277-5285
    • Wang, J.1    Gusti, V.2    Saraswati, A.3    Lo, D.D.4
  • 85
    • 0019958014 scopus 로고
    • Effect of mouse peritoneal macrophages on scrapie infectivity during extended in vitro incubation
    • PMID:6813286
    • Carp RI, Callahan SM. Effect of mouse peritoneal macrophages on scrapie infectivity during extended in vitro incubation. Intervirology 1982; 17:201-7; PMID:6813286; http://dx.doi.org/10.1159/000149289.
    • (1982) Intervirology , vol.17 , pp. 201-207
    • Carp, R.I.1    Callahan, S.M.2
  • 86
    • 21344472810 scopus 로고    scopus 로고
    • Role of gut macrophages in mice orally contaminated with scrapie or BSE
    • PMID:15964722
    • Maignien T, Shakweh M, Calvo P, Marcé D, Salès N, Fattal E, et al. Role of gut macrophages in mice orally contaminated with scrapie or BSE. Int J Pharm 2005; 298:293-304; PMID:15964722; http://dx.doi.org/10.1016/j. ijpharm.2005.02.042.
    • (2005) Int J Pharm , vol.298 , pp. 293-304
    • Maignien, T.1    Shakweh, M.2    Calvo, P.3    Marcé, D.4    Salès, N.5    Fattal, E.6
  • 87
    • 84861302844 scopus 로고    scopus 로고
    • Protective role of interferon regulatory factor 3-mediated signaling against prion infection
    • PMID:22379081
    • Ishibashi D, Atarashi R, Fuse T, Nakagaki T, Yamaguchi N, Satoh K, et al. Protective role of interferon regulatory factor 3-mediated signaling against prion infection. J Virol 2012; 86:4947-55; PMID:22379081; http://dx.doi.org/10. 1128/JVI.06326-11.
    • (2012) J Virol , vol.86 , pp. 4947-4955
    • Ishibashi, D.1    Atarashi, R.2    Fuse, T.3    Nakagaki, T.4    Yamaguchi, N.5    Satoh, K.6
  • 88
    • 0030775632 scopus 로고    scopus 로고
    • Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent
    • PMID:9333239
    • Bruce ME, Will RG, Ironside JW, McConnell I, Drummond D, Suttie A, et al. Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent. Nature 1997; 389:498-501; PMID:9333239; http://dx.doi.org/10.1038/39057.
    • (1997) Nature , vol.389 , pp. 498-501
    • Bruce, M.E.1    Will, R.G.2    Ironside, J.W.3    McConnell, I.4    Drummond, D.5    Suttie, A.6
  • 89
    • 0035940950 scopus 로고    scopus 로고
    • Estimation of epidemic size and incubation time based on age characteristics of vCJD in the United Kingdom
    • PMID:11721058
    • Valleron AJ, Boelle PY, Will R, Cesbron JY. Estimation of epidemic size and incubation time based on age characteristics of vCJD in the United Kingdom. Science 2001; 294:1726-8; PMID:11721058; http://dx.doi.org/10.1126/science. 1066838.
    • (2001) Science , vol.294 , pp. 1726-1728
    • Valleron, A.J.1    Boelle, P.Y.2    Will, R.3    Cesbron, J.Y.4
  • 91
    • 10444240976 scopus 로고    scopus 로고
    • Epidemiological evidence of higher susceptibility to vCJD in the young
    • PMID:15304199
    • Boëlle PY, Cesbron JY, Valleron AJ. Epidemiological evidence of higher susceptibility to vCJD in the young. BMC Infect Dis 2004; 4:26; PMID:15304199; http://dx.doi.org/10.1186/1471-2334-4-26.
    • (2004) BMC Infect Dis , vol.4 , pp. 26
    • Boëlle, P.Y.1    Cesbron, J.Y.2    Valleron, A.J.3
  • 92
    • 33646077904 scopus 로고    scopus 로고
    • Comparative evidence for a link between Peyer's patch development and susceptibility to transmissible spongiform encephalopathies
    • PMID:16405727
    • St. Rose SG, Hunter N, Matthews L, Foster JD, Chase-Topping ME, Kruuk LEB, et al. Comparative evidence for a link between Peyer's patch development and susceptibility to transmissible spongiform encephalopathies. BMC Infect Dis 2006; 6:5; PMID:16405727; http://dx.doi.org/10.1186/1471-2334-6-5.
    • (2006) BMC Infect Dis , vol.6 , pp. 5
    • St Rose, S.G.1    Hunter, N.2    Matthews, L.3    Foster, J.D.4    Chase-Topping, M.E.5    Kruuk, L.E.B.6
  • 93
    • 0025315195 scopus 로고
    • Kinetics of germinal center development in lymph nodes of young and aging immune mice
    • PMID:2393099
    • Szakal AK, Taylor JK, Smith JP, Kosco MH, Burton GF, Tew JJ. Kinetics of germinal center development in lymph nodes of young and aging immune mice. Anat Rec 1990; 227:475-85; PMID:2393099; http://dx.doi.org/10.1002/ar.1092270411.
    • (1990) Anat Rec , vol.227 , pp. 475-485
    • Szakal, A.K.1    Taylor, J.K.2    Smith, J.P.3    Kosco, M.H.4    Burton, G.F.5    Tew, J.J.6
  • 94
    • 0036772765 scopus 로고    scopus 로고
    • Age-related depression of FDC accessory functions and CD21 ligand-mediated repair of co-stimulation
    • PMID:12355434
    • Aydar Y, Balogh P, Tew JG, Szakal AK. Age-related depression of FDC accessory functions and CD21 ligand-mediated repair of co-stimulation. Eur J Immunol 2002; 32:2817-26; PMID:12355434; http://dx.doi.org/10.1002/1521- 4141(2002010)32:10〈2817::AIDIMMU2817〉3.0.CO;2-Z.
    • (2002) Eur J Immunol , vol.32 , pp. 2817-2826
    • Aydar, Y.1    Balogh, P.2    Tew, J.G.3    Szakal, A.K.4
  • 95
    • 0345016411 scopus 로고    scopus 로고
    • Altered regulation of FcgammaRII on aged follicular dendritic cells correlates with immunoreceptor tyrosine-based inhibition motif signaling in B cells and reduced germinal center formation
    • PMID:14634109
    • Aydar Y, Balogh P, Tew JG, Szakal AK. Altered regulation of FcgammaRII on aged follicular dendritic cells correlates with immunoreceptor tyrosine-based inhibition motif signaling in B cells and reduced germinal center formation. J Immunol 2003; 171:5975-87; PMID:14634109.
    • (2003) J Immunol , vol.171 , pp. 5975-5987
    • Aydar, Y.1    Balogh, P.2    Tew, J.G.3    Szakal, A.K.4
  • 96
    • 0842303113 scopus 로고    scopus 로고
    • Follicular dendritic cells in aging, a "bottle-neck" in the humoral immune response
    • PMID:15163101
    • Aydar Y, Balogh P, Tew JG, Szakal AK. Follicular dendritic cells in aging, a "bottle-neck" in the humoral immune response. Ageing Res Rev 2004; 3:15-29; PMID:15163101; http://dx.doi.org/10.1016/j.arr.2003.08.002.
    • (2004) Ageing Res Rev , vol.3 , pp. 15-29
    • Aydar, Y.1    Balogh, P.2    Tew, J.G.3    Szakal, A.K.4
  • 97
    • 77954100854 scopus 로고    scopus 로고
    • The effects of host age on follicular dendritic cell status dramatically impair scrapie agent neuroinvasion in aged mice
    • PMID:19786551
    • Brown KL, Wathne GJ, Sales J, Bruce ME, Mabbott NA. The effects of host age on follicular dendritic cell status dramatically impair scrapie agent neuroinvasion in aged mice. J Immunol 2009; 183:5199-207; PMID:19786551; http://dx.doi.org/10.4049/jimmunol.0802695.
    • (2009) J Immunol , vol.183 , pp. 5199-5207
    • Brown, K.L.1    Wathne, G.J.2    Sales, J.3    Bruce, M.E.4    Mabbott, N.A.5
  • 98
    • 80052617393 scopus 로고    scopus 로고
    • Age-related alterations affect the susceptibility of mice to prion infection
    • PMID:20045218
    • Avrahami D, Gabizon R. Age-related alterations affect the susceptibility of mice to prion infection. Neurobiol Aging 2011; 32:2006-15; PMID:20045218; http://dx.doi.org/10.1016/j.neurobiolaging.2009.12.015.
    • (2011) Neurobiol Aging , vol.32 , pp. 2006-2015
    • Avrahami, D.1    Gabizon, R.2
  • 99
    • 0015896507 scopus 로고
    • Developmental maturation of susceptibility to scrapie in mice
    • PMID:4632780
    • Outram GW, Dickinson AG, Fraser H. Developmental maturation of susceptibility to scrapie in mice. Nature 1973; 241:536-7; PMID:4632780; http://dx.doi.org/10.1038/241536a0.
    • (1973) Nature , vol.241 , pp. 536-537
    • Outram, G.W.1    Dickinson, A.G.2    Fraser, H.3
  • 100
    • 33645995108 scopus 로고    scopus 로고
    • Resistance of neonatal mice to scrapie is associated with inefficient infection of the immature spleen
    • PMID:16352571
    • Ierna MI, Farquhar CF, Outram GW, Bruce ME. Resistance of neonatal mice to scrapie is associated with inefficient infection of the immature spleen. J Virol 2006; 80:474-82; PMID:16352571; http://dx.doi.org/10.1128/JVI.80.1.474-82. 2006.
    • (2006) J Virol , vol.80 , pp. 474-482
    • Ierna, M.I.1    Farquhar, C.F.2    Outram, G.W.3    Bruce, M.E.4
  • 101
    • 1142273431 scopus 로고    scopus 로고
    • Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion
    • PMID:14962520
    • Llewelyn CA, Hewitt PE, Knight RSG, Amar K, Cousens S, Mackenzie J, et al. Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion. Lancet 2004; 363:417-21; PMID:14962520; http://dx.doi.org/10.1016/ S0140-6736(04)15486-X.
    • (2004) Lancet , vol.363 , pp. 417-421
    • Llewelyn, C.A.1    Hewitt, P.E.2    Knight, R.S.G.3    Amar, K.4    Cousens, S.5    Mackenzie, J.6
  • 102
    • 4043157677 scopus 로고    scopus 로고
    • Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient
    • PMID:15302196
    • Peden AH, Head MW, Ritchie DL, Bell JE, Ironside JW. Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient. Lancet 2004; 364:527-9; PMID:15302196; http://dx.doi.org/10.1016/S0140-6736(04)16811-6.
    • (2004) Lancet , vol.364 , pp. 527-529
    • Peden, A.H.1    Head, M.W.2    Ritchie, D.L.3    Bell, J.E.4    Ironside, J.W.5
  • 103
    • 33845227845 scopus 로고    scopus 로고
    • Clinical presentation and pre-mortem diagnosis of variant Creutzfeldt-Jakob disease associated with blood transfusion: A case report
    • PMID:17161728
    • Wroe SJ, Pal S, Siddique D, Hyare H, Macfarlane R, Joiner S, et al. Clinical presentation and pre-mortem diagnosis of variant Creutzfeldt-Jakob disease associated with blood transfusion: a case report. Lancet 2006; 368:2061-7; PMID:17161728; http://dx.doi.org/10.1016/S0140-6736(06)69835-8.
    • (2006) Lancet , vol.368 , pp. 2061-2067
    • Wroe, S.J.1    Pal, S.2    Siddique, D.3    Hyare, H.4    Macfarlane, R.5    Joiner, S.6
  • 105
    • 0017873041 scopus 로고
    • Pathogenesis of mouse scrapie: Effect of route of inoculation on infectivity titres and dose-response curves
    • PMID:563870
    • Kimberlin RH, Walker CA. Pathogenesis of mouse scrapie: effect of route of inoculation on infectivity titres and dose-response curves. J Comp Pathol 1978; 88:39-47; PMID:563870; http://dx.doi.org/10.1016/0021-9975(78)90059-2.
    • (1978) J Comp Pathol , vol.88 , pp. 39-47
    • Kimberlin, R.H.1    Walker, C.A.2
  • 106
    • 37349013401 scopus 로고    scopus 로고
    • Follicular shuttling of marginal zone B cells facilitates antigen transport
    • PMID:18037889
    • Cinamon G, Zachariah MA, Lam OM, Foss FW Jr, Cyster JG. Follicular shuttling of marginal zone B cells facilitates antigen transport. Nat Immunol 2008; 9:54-62; PMID:18037889; http://dx.doi.org/10.1038/ni1542.
    • (2008) Nat Immunol , vol.9 , pp. 54-62
    • Cinamon, G.1    Zachariah, M.A.2    Lam, O.M.3    Foss Jr., F.W.4    Cyster, J.G.5
  • 107
    • 0038620164 scopus 로고    scopus 로고
    • Immunologically induced, complement-dependent upregulation of the prion protein in the mouse spleen: Follicular dendritic cells versus capsule and trabeculae
    • PMID:12794132
    • Lötscher M, Recher M, Hunziker L, Klein MA. Immunologically induced, complement-dependent upregulation of the prion protein in the mouse spleen: follicular dendritic cells versus capsule and trabeculae. J Immunol 2003; 170:6040-7; PMID:12794132.
    • (2003) J Immunol , vol.170 , pp. 6040-6047
    • Lötscher, M.1    Recher, M.2    Hunziker, L.3    Klein, M.A.4
  • 108
    • 24744446203 scopus 로고    scopus 로고
    • Detection of prions in blood
    • PMID:16127436
    • Castilla J, Saá P, Soto C. Detection of prions in blood. Nat Med 2005; 11:982-5; PMID:16127436.
    • (2005) Nat Med , vol.11 , pp. 982-985
    • Castilla, J.1    Saá, P.2    Soto, C.3
  • 109
    • 0034643679 scopus 로고    scopus 로고
    • Retrospective study of prion-protein accumulation in tonsil and appendix tissues
    • PMID:10905247
    • Ironside JW, Hilton DA, Ghani A, Johnston NJ, Conyers L, McCardle LM, et al. Retrospective study of prion-protein accumulation in tonsil and appendix tissues. Lancet 2000; 355:1693-4; PMID:10905247; http://dx.doi.org/10.1016/ S0140-6736(00)02243-1.
    • (2000) Lancet , vol.355 , pp. 1693-1694
    • Ironside, J.W.1    Hilton, D.A.2    Ghani, A.3    Johnston, N.J.4    Conyers, L.5    McCardle, L.M.6
  • 110
    • 33645310177 scopus 로고    scopus 로고
    • Postmortem diagnosis of preclinical and clinical scrapie in sheep by the detection of disease-associated PrP in their rectal mucosa
    • PMID:16531580
    • González L, Dagleish MP, Bellworthy SJ, Sisó S, Stack MJ, Chaplin MJ, et al. Postmortem diagnosis of preclinical and clinical scrapie in sheep by the detection of disease-associated PrP in their rectal mucosa. Vet Rec 2006; 158:325-31; PMID:16531580; http://dx.doi.org/10.1136/vr.158.10.325.
    • (2006) Vet Rec , vol.158 , pp. 325-331
    • González, L.1    Dagleish, M.P.2    Bellworthy, S.J.3    Sisó, S.4    Stack, M.J.5    Chaplin, M.J.6
  • 111
    • 33645859052 scopus 로고    scopus 로고
    • Detection of PrP(Sc) in rectal biopsy and necropsy samples from sheep with experimental scrapie
    • PMID:16466737
    • Espenes A, Press CM, Landsverk T, Tranulis MA, Aleksandersen M, Gunnes G, et al. Detection of PrP(Sc) in rectal biopsy and necropsy samples from sheep with experimental scrapie. J Comp Pathol 2006; 134:115-25; PMID:16466737; http://dx.doi.org/10.1016/j.jcpa.2005.08.001.
    • (2006) J Comp Pathol , vol.134 , pp. 115-125
    • Espenes, A.1    Press, C.M.2    Landsverk, T.3    Tranulis, M.A.4    Aleksandersen, M.5    Gunnes, G.6
  • 113
    • 33751084832 scopus 로고    scopus 로고
    • Detection of PrP(CWD) in postmortem rectal lymphoid tissues in Rocky Mountain elk (Cervus elaphus nelsoni) infected with chronic wasting disease
    • PMID:17121082
    • Spraker TR, Gidlewski TL, Balachandran A, VerCauteren KC, Creekmore L, Munger RD. Detection of PrP(CWD) in postmortem rectal lymphoid tissues in Rocky Mountain elk (Cervus elaphus nelsoni) infected with chronic wasting disease. J Vet Diagn Invest 2006; 18:553-7; PMID:17121082; http://dx.doi.org/10.1177/ 104063870601800605.
    • (2006) J Vet Diagn Invest , vol.18 , pp. 553-557
    • Spraker, T.R.1    Gidlewski, T.L.2    Balachandran, A.3    VerCauteren, K.C.4    Creekmore, L.5    Munger, R.D.6
  • 114
    • 84856306158 scopus 로고    scopus 로고
    • Facilitated cross-species transmission of prions in extraneural tissue
    • PMID:22282814
    • Béringue V, Herzog L, Jaumain E, Reine F, Sibille P, Le Dur A, et al. Facilitated cross-species transmission of prions in extraneural tissue. Science 2012; 335:472-5; PMID:22282814; http://dx.doi.org/10.1126/science. 1215659.
    • (2012) Science , vol.335 , pp. 472-475
    • Béringue, V.1    Herzog, L.2    Jaumain, E.3    Reine, F.4    Sibille, P.5    Le Dur, A.6
  • 115
    • 26844563437 scopus 로고    scopus 로고
    • Coincident scrapie infection and nephritis lead to urinary prion excretion
    • PMID:16224026
    • Seeger H, Heikenwalder M, Zeller N, Kranich J, Schwarz P, Gaspert A, et al. Coincident scrapie infection and nephritis lead to urinary prion excretion. Science 2005; 310:324-6; PMID:16224026; http://dx.doi.org/10.1126/science. 1118829.
    • (2005) Science , vol.310 , pp. 324-326
    • Seeger, H.1    Heikenwalder, M.2    Zeller, N.3    Kranich, J.4    Schwarz, P.5    Gaspert, A.6
  • 116
    • 58849129829 scopus 로고    scopus 로고
    • Bacterial colitis increases susceptibility to oral prion disease
    • PMID:19072552
    • Sigurdson CJ, Heikenwalder M, Manco G, Barthel M, Schwarz P, Stecher B, et al. Bacterial colitis increases susceptibility to oral prion disease. J Infect Dis 2009; 199:243-52; PMID:19072552; http://dx.doi.org/10.1086/595791.
    • (2009) J Infect Dis , vol.199 , pp. 243-252
    • Sigurdson, C.J.1    Heikenwalder, M.2    Manco, G.3    Barthel, M.4    Schwarz, P.5    Stecher, B.6
  • 117
    • 0032708655 scopus 로고    scopus 로고
    • Rapid appeaance of M cells after microbial challenge is restricted at the periphery of the follicle-associated epithelium of Peyer's patch
    • PMID:10576210
    • Borghesi C, Taussig MJ, Nicoletti C. Rapid appeaance of M cells after microbial challenge is restricted at the periphery of the follicle-associated epithelium of Peyer's patch. Lab Invest 1999; 79:1393-401; PMID:10576210.
    • (1999) Lab Invest , vol.79 , pp. 1393-1401
    • Borghesi, C.1    Taussig, M.J.2    Nicoletti, C.3
  • 118
    • 0032943743 scopus 로고    scopus 로고
    • Upregulation of microsphere transport across the follicle-associated epithelium of Peyer's patch by exposure to Streptococcus pneumoniae R36a
    • PMID:10094922
    • Meynell HM, Thomas NW, James PS, Holland J, Taussig MJ, Nicoletti C. Upregulation of microsphere transport across the follicle-associated epithelium of Peyer's patch by exposure to Streptococcus pneumoniae R36a. FASEB J 1999; 13:611-9; PMID:10094922.
    • (1999) FASEB J , vol.13 , pp. 611-619
    • Meynell, H.M.1    Thomas, N.W.2    James, P.S.3    Holland, J.4    Taussig, M.J.5    Nicoletti, C.6
  • 119
    • 34247564230 scopus 로고    scopus 로고
    • The nasal cavity is a route for prion infection in hamsters
    • PMID:17301140
    • Kincaid AE, Bartz JC. The nasal cavity is a route for prion infection in hamsters. J Virol 2007; 81:4482-91; PMID:17301140; http://dx.doi.org/10.1128/ JVI.02649-06.
    • (2007) J Virol , vol.81 , pp. 4482-4491
    • Kincaid, A.E.1    Bartz, J.C.2
  • 120
    • 67449103378 scopus 로고    scopus 로고
    • Role of the lymphoreticular system in prion neuroinvasion from the oral and nasal mucosa
    • PMID:19369351
    • Bessen RA, Martinka S, Kelly J, Gonzalez D. Role of the lymphoreticular system in prion neuroinvasion from the oral and nasal mucosa. J Virol 2009; 83:6435-45; PMID:19369351; http://dx.doi.org/10.1128/JVI.00018-09.
    • (2009) J Virol , vol.83 , pp. 6435-6445
    • Bessen, R.A.1    Martinka, S.2    Kelly, J.3    Gonzalez, D.4
  • 121
    • 77952703107 scopus 로고    scopus 로고
    • Aerosol and nasal transmission of chronic wasting disease in cervidized mice
    • PMID:20164261
    • Denkers ND, Seelig DM, Telling GC, Hoover EA. Aerosol and nasal transmission of chronic wasting disease in cervidized mice. J Gen Virol 2010; 91:1651-8; PMID:20164261; http://dx.doi.org/10.1099/vir.0.017335-0.
    • (2010) J Gen Virol , vol.91 , pp. 1651-1658
    • Denkers, N.D.1    Seelig, D.M.2    Telling, G.C.3    Hoover, E.A.4
  • 122
    • 77954075928 scopus 로고    scopus 로고
    • Prion shedding from olfactory neurons into nasal secretions
    • PMID:20419120
    • Bessen RA, Shearin H, Martinka S, Boharski R, Lowe D, Wilham JM, et al. Prion shedding from olfactory neurons into nasal secretions. PLoS Pathog 2010; 6:1000837; PMID:20419120; http://dx.doi.org/10.1371/journal.ppat.1000837.
    • (2010) PLoS Pathog , vol.6 , pp. 1000837
    • Bessen, R.A.1    Shearin, H.2    Martinka, S.3    Boharski, R.4    Lowe, D.5    Wilham, J.M.6
  • 123
    • 84857076231 scopus 로고    scopus 로고
    • Accelerated shedding of prions following damage to the olfactory epithelium
    • PMID:22130543
    • Bessen RA, Wilham JM, Lowe D, Watschke CP, Shearin H, Martinka S, et al. Accelerated shedding of prions following damage to the olfactory epithelium. J Virol 2012; 86:1777-88; PMID:22130543; http://dx.doi.org/10.1128/JVI.06626-11.
    • (2012) J Virol , vol.86 , pp. 1777-1788
    • Bessen, R.A.1    Wilham, J.M.2    Lowe, D.3    Watschke, C.P.4    Shearin, H.5    Martinka, S.6
  • 124
    • 79551523008 scopus 로고    scopus 로고
    • Aerosols transmit prions to immunocompetent and immunodeficient mice
    • PMID:21249178
    • Haybaeck J, Heikenwalder M, Klevenz B, Schwarz P, Margalith I, Bridel C, et al. Aerosols transmit prions to immunocompetent and immunodeficient mice. PLoS Pathog 2011; 7:1001257; PMID:21249178; http://dx.doi.org/10.1371/journal. ppat.1001257.
    • (2011) PLoS Pathog , vol.7 , pp. 1001257
    • Haybaeck, J.1    Heikenwalder, M.2    Klevenz, B.3    Schwarz, P.4    Margalith, I.5    Bridel, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.