The effects of host age on the transport of complement-bound complexes to the spleen and the pathogenesis of intravenous scrapie infection

Journal of Virology

Volumn 86, Issue 1, 2012, Pages 25-35

  Brown, Karen L ^a   Gossner, Anton ^a   Mok, Simon ^a   Mabbott, Neil A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT; COMPLEMENT COMPONENT C4; MESSENGER RNA; PRION PROTEIN;

ADULT ANIMAL; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BRAIN INFECTION; COMPLEMENT ACTIVATION; COMPLEMENT COMPONENT C4B GENE; CONTROLLED STUDY; EMBRYO; FOLLICULAR DENDRITIC CELL; GENE; HISTOPATHOLOGY; HOST SUSCEPTIBILITY; INFECTION SENSITIVITY; LONG TERM EXPOSURE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCRAPIE; SCRAPIE AGENT; SPLEEN; VARIANT CREUTZFELDT JAKOB DISEASE; VIRAL CONTAMINATION; VIRUS LOAD; VIRUS TRANSMISSION;

AGE FACTORS; AGED, 80 AND OVER; AGING; ANIMALS; BIOLOGICAL TRANSPORT; COMPLEMENT SYSTEM PROTEINS; DENDRITIC CELLS, FOLLICULAR; DISEASE MODELS, ANIMAL; FEMALE; HOST-PATHOGEN INTERACTIONS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PRPSC PROTEINS; SCRAPIE; SPLEEN;

MUS;

EID: 84855952265     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.05581-11     Document Type: Article

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