Recent advances in targeted genome engineering in mammalian systems

Biotechnology Journal

Volumn 7, Issue 9, 2012, Pages 1074-1087

  Sun, Ning ^a   Abil, Zhanar ^a   Zhao, Huimin ^a,b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Artificial nuclease; Double strand break; Gene delivery; Gene targeting; Gene therapy

Indexed keywords

ARTIFICIAL NUCLEASE; DOUBLE-STRAND BREAKS; ENDONUCLEASES; GENE DELIVERY; GENE TARGETING; GENOME ENGINEERING; GENOME MODIFICATION; GENOMIC SEQUENCE; HOMOLOGOUS RECOMBINATION; MAMMALIAN CELLS; MAMMALIAN GENOMES; MAMMALIAN SYSTEMS; NONHOMOLOGOUS END JOINING; SITE-SPECIFIC; ZINC FINGER NUCLEASE;

GENE THERAPY; GENE TRANSFER; MAMMALS;

GENES;

CHEMOKINE RECEPTOR CCR5; CRE RECOMBINASE; ENDONUCLEASE; ENHANCED GREEN FLUORESCENT PROTEIN; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; ZINC FINGER NUCLEASE;

CELL HOMING; CELL LINE; CELL STRAIN HEK293; CELL STRAIN K 562; CHROMOSOME; CHROMOSOME BREAKAGE; CHROMOSOME DELETION; CHROMOSOME DUPLICATION; CHROMOSOME INVERSION; CHROMOSOME REARRANGEMENT; DNA BINDING MOTIF; DNA CLEAVAGE; DNA END JOINING REPAIR; DNA HELIX; DNA MODIFICATION; DNA SEQUENCE; DOUBLE STRANDED DNA BREAK; DOWNSTREAM PROCESSING; DROSOPHILA; ENZYME ACTIVE SITE; GENE DELETION; GENE DISRUPTION; GENE DUPLICATION; GENE EXPRESSION; GENE INACTIVATION; GENE INSERTION; GENE MUTATION; GENE REPLACEMENT THERAPY; GENE TARGETING; GENETIC ENGINEERING; GLOBIN GENE; HELA CELL; HUMAN; IMMUNE RESPONSE; MAMMAL CELL; MONOGENIC DISORDER; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; REPORTER GENE; REVIEW; TARGETED GENE REPAIR; TRANSCRIPTION INITIATION; VIRUS GENOME; WILD TYPE; XANTHOMONAS;

ANIMALS; BIOTECHNOLOGY; ENDONUCLEASES; GENETIC ENGINEERING; GENOMICS; MAMMALS;

MAMMALIA; MUS;

EID: 84866013226     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201200038     Document Type: Review

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