Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins

Nucleic Acids Research

Volumn 37, Issue 5, 2009, Pages 1650-1662

  Li, Hui ^a,b   Pellenz, Stefan ^a,b   Ulge, Umut ^a,b   Stoddard, Barry L ^b,c   Monnat Jr , Raymond J ^a,b,c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Northwest Genome Engineering Consortium   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREL PROTEIN; ENDONUCLEASE; HOMODIMER; MSOL PROTEIN; PROTEIN PRECURSOR; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ARTICLE; CONTROLLED STUDY; DNA CLEAVAGE; DNA MODIFICATION; DNA REPAIR; ENZYME STRUCTURE; GENE EXPRESSION; GENE TARGETING; GENETIC ENGINEERING; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; STRUCTURE ANALYSIS;

AMINO ACID MOTIFS; CELL LINE; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; DNA RESTRICTION ENZYMES; ENDODEOXYRIBONUCLEASES; ENZYME PRECURSORS; GENE LIBRARY; HUMANS; MODELS, MOLECULAR; PROTEIN ENGINEERING; THERMODYNAMICS;

EID: 63249127088     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp004     Document Type: Article

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