Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus

Nucleic Acids Research

Volumn 39, Issue 2, 2011, Pages 729-743

  Muñoz, Inés G ^a   Prieto, Jesús ^a   Subramanian, Sunita ^a   Coloma, Javier ^a   Redondo, Pilar ^a   Villate, Maider ^b   Merino, Nekane ^b   Marenchino, Marco ^a   D'Abramo, Marco ^a   Gervasio, Francesco L ^a   Grizot, Sylvestre ^c   Daboussi, Fayza ^c   Smith, Julianne ^c   Chion Sotinel, Isabelle ^c   Pâques, Frédéric ^c   Duchateau, Philippe ^c   Alibés, Andreu ^d   Stricher, Franois ^d   Serrano, Luis ^d,e   Blanco, Francisco J ^b,f   Montoya, Guillermo ^a   more..

^a Structural Biology and Biocomputing Programme   (Spain)

^b CIC BIOGUNE   (Spain)

^c Arvid Wallgrens Backe 20   (France)

^d CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^e INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^f BASQUE FOUNDATION FOR SCIENCE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ENDONUCLEASE; MEGANUCLEASE; RAG1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA CLEAVAGE; DNA CONFORMATION; DNA DETERMINATION; DNA SEQUENCE; ENZYME ENGINEERING; GENE LOCUS; GENE MUTATION; GENE TARGETING; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CELL LINE; DNA; DNA CLEAVAGE; DNA REPAIR; DNA RESTRICTION ENZYMES; GENE TARGETING; GENES, RAG-1; GENETIC LOCI; HUMANS; MODELS, MOLECULAR; MUTATION; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN ENGINEERING; RECOMBINATION, GENETIC;

EID: 79551491956     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq801     Document Type: Article

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