-
1
-
-
4344671644
-
Effector function of human tumor-specific CD8 T cells in melanoma lesions: A state of local functional tolerance
-
Zippelius A, Batard P, Rubio-Godoy V, et al. Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. Cancer Res. 2004;64:2865-2873.
-
(2004)
Cancer Res
, vol.64
, pp. 2865-2873
-
-
Zippelius, A.1
Batard, P.2
Rubio-Godoy, V.3
-
2
-
-
33645723257
-
On the facultative anaerobiosis of cancer cells and its use in chemotherapy]
-
Warburg O. [On the facultative anaerobiosis of cancer cells and its use in chemotherapy]. Munch Med Wochenschr. 1961;103:2504-2506.
-
(1961)
Munch Med Wochenschr
, vol.103
, pp. 2504-2506
-
-
Warburg, O.1
-
3
-
-
0030045543
-
Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: Similarities with the regulation of erythropoietin
-
Ebert BL, Gleadle JM, O'Rourke JF, et al. Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: similarities with the regulation of erythropoietin. Biochem J. 1996;313(pt 3):809-814.
-
(1996)
Biochem J
, vol.313
, Issue.PART 3
, pp. 809-814
-
-
Ebert, B.L.1
Gleadle, J.M.2
O'Rourke, J.F.3
-
4
-
-
0034326273
-
Coordinate up-regulation of hypoxia inducible factor (HIF)-1alpha and HIF-1 target genes during multi-stage epidermal carcinogenesis and wound healing
-
Elson DA, Ryan HE, Snow JW, Johnson R, Arbeit JM. Coordinate up-regulation of hypoxia inducible factor (HIF)-1alpha and HIF-1 target genes during multi-stage epidermal carcinogenesis and wound healing. Cancer Res. 2000;60:6189-6195.
-
(2000)
Cancer Res
, vol.60
, pp. 6189-6195
-
-
Elson, D.A.1
Ryan, H.E.2
Snow, J.W.3
Johnson, R.4
Arbeit, J.M.5
-
6
-
-
0030659531
-
VSRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: Involvement of HIF-1 in tumor progression
-
Jiang BH, Agani F, Passaniti A, Semenza GL. VSRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression. Cancer Res. 1997;57:5328-5335.
-
(1997)
Cancer Res
, vol.57
, pp. 5328-5335
-
-
Jiang, B.H.1
Agani, F.2
Passaniti, A.3
Semenza, G.L.4
-
7
-
-
0033870281
-
The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages
-
Talks KL, Turley H, Gatter KC, et al. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol. 2000;157:411-421.
-
(2000)
Am J Pathol
, vol.157
, pp. 411-421
-
-
Talks, K.L.1
Turley, H.2
Gatter, K.C.3
-
8
-
-
0037189542
-
Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis
-
Lu H, Forbes RA, Verma A. Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis. J Biol Chem. 2002;277:23111-23115.
-
(2002)
J Biol Chem
, vol.277
, pp. 23111-23115
-
-
Lu, H.1
Forbes, R.A.2
Verma, A.3
-
9
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer. 2004;4:891-899.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
10
-
-
0034652620
-
High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers
-
Walenta S, Wetterling M, Lehrke M, et al. High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers. Cancer Res. 2000;60:916-921.
-
(2000)
Cancer Res
, vol.60
, pp. 916-921
-
-
Walenta, S.1
Wetterling, M.2
Lehrke, M.3
-
11
-
-
0031029634
-
Correlation of high lactate levels in head and neck tumors with incidence of metastasis
-
Walenta S, Salameh A, Lyng H, et al. Correlation of high lactate levels in head and neck tumors with incidence of metastasis. Am J Pathol. 1997;150:409-415.
-
(1997)
Am J Pathol
, vol.150
, pp. 409-415
-
-
Walenta, S.1
Salameh, A.2
Lyng, H.3
-
12
-
-
3242798360
-
Lactate in solid malignant tumors: Potential basis of a metabolic classification in clinical oncology
-
Walenta S, Schroeder T, Mueller-Klieser W. Lactate in solid malignant tumors: potential basis of a metabolic classification in clinical oncology. Curr Med Chem. 2004;11:2195-2204.
-
(2004)
Curr Med Chem
, vol.11
, pp. 2195-2204
-
-
Walenta, S.1
Schroeder, T.2
Mueller-Klieser, W.3
-
13
-
-
0030885709
-
The clinical value of lactate dehydrogenase in serum: A quantitative review
-
Huijgen HJ, Sanders GT, Koster RW, Vreeken J, Bossuyt PM. The clinical value of lactate dehydrogenase in serum: a quantitative review. Eur J Clin Chem Clin Biochem. 1997;35:569-579.
-
(1997)
Eur J Clin Chem Clin Biochem
, vol.35
, pp. 569-579
-
-
Huijgen, H.J.1
Sanders, G.T.2
Koster, R.W.3
Vreeken, J.4
Bossuyt, P.M.5
-
14
-
-
0029921389
-
Lactic acidosis and hypoglycemia in a patient with high-grade non-Hodgkin's lymphoma and elevated circulating TNF-alpha
-
Durig J, Fiedler W, de Wit M, Steffen M, Hossfeld DK. Lactic acidosis and hypoglycemia in a patient with high-grade non-Hodgkin's lymphoma and elevated circulating TNF-alpha. Ann Hematol. 1996;72:97-99.
-
(1996)
Ann Hematol
, vol.72
, pp. 97-99
-
-
Durig, J.1
Fiedler, W.2
de Wit, M.3
Steffen, M.4
Hossfeld, D.K.5
-
15
-
-
0025753267
-
The energy state of tumor-bearing rats
-
Argiles JM, Lopez-Soriano FJ. The energy state of tumor-bearing rats. J Biol Chem. 1991;266:2978-2982.
-
(1991)
J Biol Chem
, vol.266
, pp. 2978-2982
-
-
Argiles, J.M.1
Lopez-Soriano, F.J.2
-
16
-
-
17044422629
-
Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells
-
Cham CM, Gajewski TF. Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells. J Immunol. 2005;174:4670-4677.
-
(2005)
J Immunol
, vol.174
, pp. 4670-4677
-
-
Cham, C.M.1
Gajewski, T.F.2
-
17
-
-
1842581892
-
Regulation of T lymphocyte metabolism
-
Frauwirth KA, Thompson CB. Regulation of T lymphocyte metabolism. J Immunol. 2004;172:4661-4665.
-
(2004)
J Immunol
, vol.172
, pp. 4661-4665
-
-
Frauwirth, K.A.1
Thompson, C.B.2
-
18
-
-
0027418622
-
Transport of lactate and other monocarboxylates across mammalian plasma membranes
-
Poole RC, Halestrap AP. Transport of lactate and other monocarboxylates across mammalian plasma membranes. Am J Physiol. 1993;264:C761-C782.
-
(1993)
Am J Physiol
, vol.264
-
-
Poole, R.C.1
Halestrap, A.P.2
-
19
-
-
0033569442
-
The proton-linked monocarboxylate transporter (MCT) family: Structure, function and regulation
-
Halestrap AP, Price NT. The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation. Biochem J. 1999;343(pt 2):281-299.
-
(1999)
Biochem J
, vol.343
, Issue.PART 2
, pp. 281-299
-
-
Halestrap, A.P.1
Price, N.T.2
-
20
-
-
8744249212
-
Presence and localization of three lactic acid transporters (MCT1, -2, and -4) in separated human granulocytes, lymphocytes, and monocytes
-
Merezhinskaya N, Ogunwuyi SA, Mullick FG, Fishbein WN. Presence and localization of three lactic acid transporters (MCT1, -2, and -4) in separated human granulocytes, lymphocytes, and monocytes. J Histochem Cytochem. 2004;52:1483-1493.
-
(2004)
J Histochem Cytochem
, vol.52
, pp. 1483-1493
-
-
Merezhinskaya, N.1
Ogunwuyi, S.A.2
Mullick, F.G.3
Fishbein, W.N.4
-
21
-
-
0028154509
-
Direct evidence to support the immunosurveillance concept in a human regressive melanoma
-
Mackensen A, Carcelain G, Viel S, et al. Direct evidence to support the immunosurveillance concept in a human regressive melanoma. J Clin Invest. 1994;93:1397-1402.
-
(1994)
J Clin Invest
, vol.93
, pp. 1397-1402
-
-
Mackensen, A.1
Carcelain, G.2
Viel, S.3
-
22
-
-
0037442228
-
Survival and tumor localization of adoptively transferred Melan-A-specific T cells in melanoma patients
-
Meidenbauer N, Marienhagen J, Laumer M, et al. Survival and tumor localization of adoptively transferred Melan-A-specific T cells in melanoma patients. J Immunol. 2003;170:2161-2169.
-
(2003)
J Immunol
, vol.170
, pp. 2161-2169
-
-
Meidenbauer, N.1
Marienhagen, J.2
Laumer, M.3
-
23
-
-
0036132898
-
An improved flow cytometric assay for the determination of cytotoxic T lymphocyte activity
-
Fischer K, Andreesen R, Mackensen A. An improved flow cytometric assay for the determination of cytotoxic T lymphocyte activity. J Immunol Methods. 2002;259:159-169.
-
(2002)
J Immunol Methods
, vol.259
, pp. 159-169
-
-
Fischer, K.1
Andreesen, R.2
Mackensen, A.3
-
25
-
-
0038306468
-
Novel polyamine coating providing non-covalent deactivation and reversed electroosmotic flow of fused-silica capillaries for capillary electrophoresis
-
Hardenborg E, Zuberovic A, Ullsten S, et al. Novel polyamine coating providing non-covalent deactivation and reversed electroosmotic flow of fused-silica capillaries for capillary electrophoresis. J Chromatogr A. 2003;1003:217-221.
-
(2003)
J Chromatogr A
, vol.1003
, pp. 217-221
-
-
Hardenborg, E.1
Zuberovic, A.2
Ullsten, S.3
-
26
-
-
0037093109
-
Simultaneous determination of anionic intermediates for Bacillus subtilis metabolic pathways by capillary electrophoresis electrospray ionization mass spectrometry
-
Soga T, Ueno Y, Naraoka H, et al. Simultaneous determination of anionic intermediates for Bacillus subtilis metabolic pathways by capillary electrophoresis electrospray ionization mass spectrometry. Anal Chem. 2002;74:2233-2239.
-
(2002)
Anal Chem
, vol.74
, pp. 2233-2239
-
-
Soga, T.1
Ueno, Y.2
Naraoka, H.3
-
27
-
-
0033485764
-
Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression
-
Lee KH, Wang E, Nielsen MB, et al. Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression. J Immunol. 1999;163:6292-6300.
-
(1999)
J Immunol
, vol.163
, pp. 6292-6300
-
-
Lee, K.H.1
Wang, E.2
Nielsen, M.B.3
-
28
-
-
0034662982
-
Status of activation of circulating vaccine-elicited CD8+ T cells
-
Nielsen MB, Monsurro V, Migueles SA, et al. Status of activation of circulating vaccine-elicited CD8+ T cells. J Immunol. 2000;165:2287-2296.
-
(2000)
J Immunol
, vol.165
, pp. 2287-2296
-
-
Nielsen, M.B.1
Monsurro, V.2
Migueles, S.A.3
-
29
-
-
0032844479
-
An expanded peripheral T cell population to a cytotoxic T lymphocyte (CTL)-defined, melanocyte-specific antigen in metastatic melanoma patients impacts on generation of peptide-specific CTLs but does not overcome tumor escape from immune surveillance in metastatic lesions
-
Anichini A, Molla A, Mortarini R, et al. An expanded peripheral T cell population to a cytotoxic T lymphocyte (CTL)-defined, melanocyte-specific antigen in metastatic melanoma patients impacts on generation of peptide-specific CTLs but does not overcome tumor escape from immune surveillance in metastatic lesions. J Exp Med. 1999;190:651-667.
-
(1999)
J Exp Med
, vol.190
, pp. 651-667
-
-
Anichini, A.1
Molla, A.2
Mortarini, R.3
-
30
-
-
0027453988
-
Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma
-
Nakagomi H, Petersson M, Magnusson I, et al. Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma. Cancer Res. 1993;53:5610-5612.
-
(1993)
Cancer Res
, vol.53
, pp. 5610-5612
-
-
Nakagomi, H.1
Petersson, M.2
Magnusson, I.3
-
31
-
-
0033056073
-
Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients
-
Lee PP, Yee C, Savage PA, et al. Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients. Nat Med. 1999;5:677-685.
-
(1999)
Nat Med
, vol.5
, pp. 677-685
-
-
Lee, P.P.1
Yee, C.2
Savage, P.A.3
-
32
-
-
0034880059
-
Interleukin-10 expressed at early tumour sites induces subsequent generation of CD4(+) T-regulatory cells and systemic collapse of antitumour immunity
-
Seo N, Hayakawa S, Takigawa M, Tokura Y. Interleukin-10 expressed at early tumour sites induces subsequent generation of CD4(+) T-regulatory cells and systemic collapse of antitumour immunity. Immunology. 2001;103:449-457.
-
(2001)
Immunology
, vol.103
, pp. 449-457
-
-
Seo, N.1
Hayakawa, S.2
Takigawa, M.3
Tokura, Y.4
-
33
-
-
33344467760
-
Tumor-derived lactic acid modulates dendritic cell activation and antigen expression
-
Gottfried E, Kunz-Schughart LA, Ebner S, et al. Tumor-derived lactic acid modulates dendritic cell activation and antigen expression. Blood. 2006;107:2013-2021.
-
(2006)
Blood
, vol.107
, pp. 2013-2021
-
-
Gottfried, E.1
Kunz-Schughart, L.A.2
Ebner, S.3
-
34
-
-
0022340304
-
Regulation of cytotoxic T-lymphocyte activation by L-lactate and pyruvate
-
Mihm S, Droge W. Regulation of cytotoxic T-lymphocyte activation by L-lactate and pyruvate. Cell Immunol. 1985;96:235-240.
-
(1985)
Cell Immunol
, vol.96
, pp. 235-240
-
-
Mihm, S.1
Droge, W.2
-
35
-
-
0028080336
-
pH-dependent LAK cell cytotoxicity
-
Severin T, Muller B, Giese G, et al. pH-dependent LAK cell cytotoxicity. Tumour Biol. 1994;15:304-310.
-
(1994)
Tumour Biol
, vol.15
, pp. 304-310
-
-
Severin, T.1
Muller, B.2
Giese, G.3
-
36
-
-
0026784913
-
Influence of tumour physico-chemical conditions on interleukin-2-stimulated lymphocyte proliferation
-
Loeffler DA, Juneau PL, Masserant S. Influence of tumour physico-chemical conditions on interleukin-2-stimulated lymphocyte proliferation. Br J Cancer. 1992;66:619-622.
-
(1992)
Br J Cancer
, vol.66
, pp. 619-622
-
-
Loeffler, D.A.1
Juneau, P.L.2
Masserant, S.3
-
37
-
-
0035071662
-
The effects of extracellular pH on immune function
-
Lardner A. The effects of extracellular pH on immune function. J Leukoc Biol. 2001;69:522-530.
-
(2001)
J Leukoc Biol
, vol.69
, pp. 522-530
-
-
Lardner, A.1
-
38
-
-
0035108844
-
Post-transcriptional effects of extracellular pH on tumour necrosis factor-alpha production in RAW 246.7 and J774 A.1 cells
-
Heming TA, Tuazon DM, Dave SK, et al. Post-transcriptional effects of extracellular pH on tumour necrosis factor-alpha production in RAW 246.7 and J774 A.1 cells. Clin Sci (Lond). 2001;100:259-266.
-
(2001)
Clin Sci (Lond)
, vol.100
, pp. 259-266
-
-
Heming, T.A.1
Tuazon, D.M.2
Dave, S.K.3
-
39
-
-
0025721115
-
Comparative studies of the cytotoxic T lymphocyte-mediated cytotoxicity and of extracellular ATP-induced cell lysis: Different requirements in extracellular Mg2 and pH
-
Redegeld F, Filippini A, Sitkovsky M. Comparative studies of the cytotoxic T lymphocyte-mediated cytotoxicity and of extracellular ATP-induced cell lysis: different requirements in extracellular Mg2 and pH. J Immunol. 1991;147:3638-3645.
-
(1991)
J Immunol
, vol.147
, pp. 3638-3645
-
-
Redegeld, F.1
Filippini, A.2
Sitkovsky, M.3
-
40
-
-
0024281372
-
Cell and environment interactions in tumor microregions: The multicell spheroid model
-
Sutherland RM. Cell and environment interactions in tumor microregions: the multicell spheroid model. Science. 1988;240:177-184.
-
(1988)
Science
, vol.240
, pp. 177-184
-
-
Sutherland, R.M.1
-
41
-
-
0026093552
-
Regulation of glycolysis in the erythrocyte: Role of the lactate/pyruvate and NAD/NADH ratios
-
Tilton WM, Seaman C, Carriero D, Piomelli S. Regulation of glycolysis in the erythrocyte: role of the lactate/pyruvate and NAD/NADH ratios. J Lab Clin Med. 1991;118:146-152.
-
(1991)
J Lab Clin Med
, vol.118
, pp. 146-152
-
-
Tilton, W.M.1
Seaman, C.2
Carriero, D.3
Piomelli, S.4
-
42
-
-
33644790739
-
Monocarboxylate transporter MCT1 is a target for immunosuppression
-
Murray CM, Hutchinson R, Bantick JR, et al. Monocarboxylate transporter MCT1 is a target for immunosuppression. Nat Chem Biol. 2005;1:371-376.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 371-376
-
-
Murray, C.M.1
Hutchinson, R.2
Bantick, J.R.3
-
43
-
-
0027938204
-
Demonstration of organic anion transport in T lymphocytes: L-lactate and fluo-3 are target molecules
-
Sommer F, Bischof S, Rollinghoff M, Lohoff M. Demonstration of organic anion transport in T lymphocytes: L-lactate and fluo-3 are target molecules. J Immunol. 1994;153:3523-3532.
-
(1994)
J Immunol
, vol.153
, pp. 3523-3532
-
-
Sommer, F.1
Bischof, S.2
Rollinghoff, M.3
Lohoff, M.4
|