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Volumn 267, Issue 5, 2010, Pages 515-525

Proton pump inhibitor-induced tumour cell death by inhibition of a detoxification mechanism: Symposium

Author keywords

Cancer; Cancer chemotherapy; Detoxification enzymes; Drug resistance; Reactive oxygen species; Therapeutics

Indexed keywords

CASPASE; CISPLATIN; DOXORUBICIN; FLUOROURACIL; PROTON PUMP; PROTON PUMP INHIBITOR; REACTIVE OXYGEN METABOLITE; VINBLASTINE;

EID: 77950501364     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2010.02225.x     Document Type: Conference Paper
Times cited : (99)

References (84)
  • 1
    • 0023546884 scopus 로고
    • Biologic considerations for drug targeting in cancer patients
    • Welch DR. Biologic considerations for drug targeting in cancer patients. Cancer Treat Rev 1987 14 : 351 358.
    • (1987) Cancer Treat Rev , vol.14 , pp. 351-358
    • Welch, D.R.1
  • 2
    • 66449133323 scopus 로고    scopus 로고
    • A change of strategy in the war on cancer
    • Gatenby RA. A change of strategy in the war on cancer. Nature 2009 459 : 508 509.
    • (2009) Nature , vol.459 , pp. 508-509
    • Gatenby, R.A.1
  • 4
    • 21844474548 scopus 로고    scopus 로고
    • Proton pump inhibitors may reduce tumour resistance
    • DOI 10.1517/14656566.6.7.1049
    • De Milito A, Fais S. Tumor acidity, chemoresistance and proton pump inhibitors. Future Oncol 2005 1 : 779 786. (Pubitemid 40959470)
    • (2005) Expert Opinion on Pharmacotherapy , vol.6 , Issue.7 , pp. 1049-1054
    • De Milito, A.1    Fais, S.2
  • 7
    • 0027373117 scopus 로고
    • Vacuolar-type H+-ATPases are functionally expressed in plasma membranes of human tumor cells
    • Martinez-Zaguilan R, Lynch RM, Martinez GM, Gillies RJ. Vacuolar-type Hα-ATPases are functionally expressed in plasma membranes of human tumor cells. Am J Physiol Cell Physiol 1993 265 : C1015 29. (Pubitemid 2006273)
    • (1993) AM.J.PHYSIOL. , vol.265 , Issue.4 PART 1
    • Martinez-Zaguilan, R.1    Lynch, R.M.2    Martinez, G.M.3    Gillies, R.J.4
  • 8
    • 0032080644 scopus 로고    scopus 로고
    • Heterogeneity of intracellular pH and of mechanisms that regulate intracellular pH in populations of cultured cells
    • Lee AH, Tannock IF. Heterogeneity of intracellular pH and of mechanisms that regulate intracellular pH in populations of cultured cells. Cancer Res 1998 58 : 1901 1908. (Pubitemid 28217465)
    • (1998) Cancer Research , vol.58 , Issue.9 , pp. 1901-1908
    • Lee, A.H.1    Tannock, I.F.2
  • 10
    • 33746149756 scopus 로고    scopus 로고
    • Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice
    • DOI 10.1158/0008-5472.CAN-06-0983
    • Rofstad EK, Mathiesen B, Kindem K, Galappathi K. Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice. Cancer Res 2006 66 : 6699 6707. (Pubitemid 44085627)
    • (2006) Cancer Research , vol.66 , Issue.13 , pp. 6699-6707
    • Rofstad, E.K.1    Mathiesen, B.2    Kindem, K.3    Galappathi, K.4
  • 12
    • 0034884690 scopus 로고    scopus 로고
    • Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone
    • DOI 10.1038/sj.neo.7900151
    • Raghunand N, Mahobey B, van Sluis R, Baggett B, Gillies RJ. Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone. Neoplasia 2001 3 : 227 235. (Pubitemid 32747571)
    • (2001) Neoplasia , vol.3 , Issue.3 , pp. 227-235
    • Raghunand, N.1    Mahoney, B.2    Van Sluis, R.3    Baggett, B.4    Gillies, R.J.5
  • 13
    • 0345791482 scopus 로고    scopus 로고
    • Extracellular acidification alters lysosomal trafficking in human breast cancer cells
    • Glunde K, Guggino SE, Solaiyappan M, Pathak AP, Ichikawaz Y, Bhujwalla ZM. Extracellular acidification alters lysosomal trafficking in human breast cancer cells. Neoplasia 2003 5 : 533 545. (Pubitemid 38045090)
    • (2003) Neoplasia , vol.5 , Issue.6 , pp. 533-545
    • Glunde, K.1    Guggino, S.E.2    Solaiyappan, M.3    Pathak, A.P.4    Ichikawa, Y.5    Bhujwalla, Z.M.6
  • 16
    • 33645750798 scopus 로고    scopus 로고
    • Cannibalism of live lymphocytes by human metastatic but not primary melanoma cells
    • Lugini L, Matarrese P, Tinari A et al. Cannibalism of live lymphocytes by human metastatic but not primary melanoma cells. Cancer Res 2006 66 : 3629 3638.
    • (2006) Cancer Res , vol.66 , pp. 3629-3638
    • Lugini, L.1    Matarrese, P.2    Tinari, A.3
  • 17
    • 36048968119 scopus 로고    scopus 로고
    • Cannibalism: A way to feed on metastatic tumors
    • DOI 10.1016/j.canlet.2007.09.014, PII S0304383507004235
    • Fais S. Cannibalism: a way to feed on metastatic tumors. Cancer Lett 2007 258 : 155 164. (Pubitemid 350101021)
    • (2007) Cancer Letters , vol.258 , Issue.2 , pp. 155-164
    • Fais, S.1
  • 18
    • 34548801365 scopus 로고    scopus 로고
    • Regulation of vacuolar pH and its modulation by some microbial species
    • DOI 10.1128/MMBR.00003-07
    • Huynh KK, Grinstein S. Regulation of vacuolar pH and its modulation by some microbial species. Microbiol Mol Biol Rev 2007 71 : 452 462. (Pubitemid 47429280)
    • (2007) Microbiology and Molecular Biology Reviews , vol.71 , Issue.3 , pp. 452-462
    • Huynh, K.K.1    Grinstein, S.2
  • 19
    • 56449121030 scopus 로고    scopus 로고
    • Energetic problems faced by micro-organisms growing or surviving on parsimonious energy sources and at acidic pH: I. Acidithiobacillus ferrooxidans as a paradigm
    • Ferguson SJ, Ingledew WJ. Energetic problems faced by micro-organisms growing or surviving on parsimonious energy sources and at acidic pH: I. Acidithiobacillus ferrooxidans as a paradigm. Biochim Biophys Acta 2008 1777 : 1471 1479.
    • (2008) Biochim Biophys Acta , vol.1777 , pp. 1471-1479
    • Ferguson, S.J.1    Ingledew, W.J.2
  • 20
    • 50649120655 scopus 로고    scopus 로고
    • Vacuolar and plasma membrane proton pumps collaborate to achieve cytosolic pH homeostasis in yeast
    • Martínez-Muñoz GA, Kane P. Vacuolar and plasma membrane proton pumps collaborate to achieve cytosolic pH homeostasis in yeast. J Biol Chem 2008 283 : 20309 20319.
    • (2008) J Biol Chem , vol.283 , pp. 20309-20319
    • Martínez-Muñoz, G.A.1    Kane, P.2
  • 21
    • 4344699403 scopus 로고    scopus 로고
    • Role of carbonic anhydrase IX in human tumor cell growth, survival, and invasion
    • DOI 10.1158/0008-5472.CAN-03-2224
    • Robertson N, Potter C, Harris AL. Role of carbonic anhydrase IX in human tumor cell growth, survival, invasion. Cancer Res 2004 64 : 6160 6165. (Pubitemid 39129417)
    • (2004) Cancer Research , vol.64 , Issue.17 , pp. 6160-6165
    • Robertson, N.1    Potter, C.2    Harris, A.L.3
  • 22
    • 0026683638 scopus 로고
    • P-glycoprotein as multidrug transporter: A critical review of current multidrug resistant cell lines
    • Nielsen D, Skovsgaard T. P-glycoprotein as multidrug transporter: a critical review of current multidrug resistant cell lines. Biochim Biophys Acta 1992 1139 : 169 183.
    • (1992) Biochim Biophys Acta , vol.1139 , pp. 169-183
    • Nielsen, D.1    Skovsgaard, T.2
  • 23
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 1993 62 : 385 427. (Pubitemid 23237876)
    • (1993) Annual Review of Biochemistry , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 24
    • 0028143350 scopus 로고
    • Is P-glyccoprotein a potential target for reversing clinical drug resistance?
    • Dalton WS. Is P-glyccoprotein a potential target for reversing clinical drug resistance? Curr Opin Oncol 1994 6 : 595 600.
    • (1994) Curr Opin Oncol , vol.6 , pp. 595-600
    • Dalton, W.S.1
  • 25
    • 0032904346 scopus 로고    scopus 로고
    • Enhancement of chemotherapy by manipulation of tumor pH
    • Raghunand N, He X, van Sluis R et al. Enhancement of chemotherapy by manipulation of tumor pH. Br J Cancer 1999 80 : 1005 1011.
    • (1999) Br J Cancer , vol.80 , pp. 1005-1011
    • Raghunand, N.1    He, X.2    Van Sluis, R.3
  • 27
    • 0027466646 scopus 로고
    • Overexpression of a M 110,000 vesicular protein in non-P-glycoprotein- mediated multidrug resistance
    • Scheper RJ, Broxterman HJ, Sceffer GL et al. Overexpression of a M 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance. Cancer Res 1993 53 : 1475 1479.
    • (1993) Cancer Res , vol.53 , pp. 1475-1479
    • Scheper, R.J.1    Broxterman, H.J.2    Sceffer, G.L.3
  • 30
    • 0141888537 scopus 로고    scopus 로고
    • The role of ABC transporters in clinical practice
    • DOI 10.1634/theoncologist.8-5-411
    • Leonard GD, Fojo T, Bates SE. The role of ABC transporters in clinical practice. Oncologist 2003 8 : 411 424. (Pubitemid 37238869)
    • (2003) Oncologist , vol.8 , Issue.5 , pp. 411-424
    • Leonard, G.D.1    Fojo, T.2    Bates, S.E.3
  • 31
    • 0028128073 scopus 로고
    • Intracellular pH and the control of multi-drug resistance
    • Simon S, Roy D, Schindler M. Intracellular pH and the control of multi-drug resistance. Proc Natl Acad Sci USA 1994 91 : 1128 1132.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1128-1132
    • Simon, S.1    Roy, D.2    Schindler, M.3
  • 32
    • 0141786825 scopus 로고    scopus 로고
    • Tumor acidity, ion trapping and chemotherapeutics: I. Acid pH affects the distribution of chemotherapeutic agents in vitro
    • DOI 10.1016/S0006-2952(03)00467-2
    • Mahoney BP, Raghunand N, Baggett B, Gillies RJ. Tumor acidity, ion trapping and chemotherapeutics. I. Acid pH affects the distribution of chemotherapeutic agents in vitro. Biochem Pharmacol 2003 66 : 1207 1218. (Pubitemid 37130296)
    • (2003) Biochemical Pharmacology , vol.66 , Issue.7 , pp. 1207-1218
    • Mahoney, B.P.1    Raghunand, N.2    Baggett, B.3    Gillies, R.J.4
  • 33
    • 0034143570 scopus 로고    scopus 로고
    • PH and drug resistance in tumors
    • DOI 10.1054/drup.2000.0119
    • Raghunand N, Gillies RJ. pH and drug resistance in tumors. Drug Resist Updat 2000 3 : 39 47. (Pubitemid 30246567)
    • (2000) Drug Resistance Updates , vol.3 , Issue.1 , pp. 39-47
    • Raghunand, N.1    Gillies, R.J.2
  • 34
    • 0032543207 scopus 로고    scopus 로고
    • Defective acidification in human breast tumor cells and implications for chemotherapy
    • DOI 10.1084/jem.187.10.1583
    • Altan N, Chen Y, Schindler M, Simon SM. Defective acidification in human breast tumor cells and implications for chemotherapy. J Exp Med 1998 187 : 1583 1598. (Pubitemid 28235100)
    • (1998) Journal of Experimental Medicine , vol.187 , Issue.10 , pp. 1583-1598
    • Altan, N.1    Chen, Y.2    Schindler, M.3    Simon, S.M.4
  • 35
    • 71749102668 scopus 로고    scopus 로고
    • Microenvironmental pH is a key factor for exosome traffic in tumor cells
    • Parolini I, Federici C, Raggi C et al. Microenvironmental pH is a key factor for exosome traffic in tumor cells. J Biol Chem 2009 284 : 34211 34222.
    • (2009) J Biol Chem , vol.284 , pp. 34211-34222
    • Parolini, I.1    Federici, C.2    Raggi, C.3
  • 36
    • 0037442806 scopus 로고    scopus 로고
    • +-ATPase impair the preferential accumulation of daunomycin in lysosomes and reverse the resistance to anthracyclines in drug-resistant renal epithelial cells
    • DOI 10.1042/BJ20021411
    • Ouar Z, Bens M, Vignes C et al. Inhibitors of vacuolar H+-ATPase impair the preferential accumulation of daunomycin in lysosomes and reverse the resistance to anthracyclines in drug-resistant renal epithelial cells. Biochem J 2003 370 : 185 193. (Pubitemid 36259431)
    • (2003) Biochemical Journal , vol.370 , Issue.1 , pp. 185-193
    • Ouar, Z.1    Bens, M.2    Vignes, C.3    Paulais, M.4    Pringel, C.5    Fleury, J.6    Cluzeaud, F.7    Lacave, R.8    Vandewalle, A.9
  • 38
    • 67649354220 scopus 로고    scopus 로고
    • Proton pump inhibitors: Actions and reactions
    • Mullin JM, Gabello M, Murray LJ et al. Proton pump inhibitors: actions and reactions. Drug Discov Today 2009 14 : 647 660.
    • (2009) Drug Discov Today , vol.14 , pp. 647-660
    • Mullin, J.M.1    Gabello, M.2    Murray, L.J.3
  • 39
    • 36349001899 scopus 로고    scopus 로고
    • +-ATPases as a new strategy against cancer
    • DOI 10.1158/0008-5472.CAN-07-1805
    • Fais S, De Milito A, You H, Qin W. Targeting vacuolar H+-ATPases as a new strategy against cancers. Cancer Res 2007 67 : 10627 10630. (Pubitemid 350145883)
    • (2007) Cancer Research , vol.67 , Issue.22 , pp. 10627-10630
    • Fais, S.1    De Milito, A.2    You, H.3    Qin, W.4
  • 40
    • 62149142874 scopus 로고    scopus 로고
    • V-ATPase functions in normal and disease processes
    • Hinton A, Bond S, Forgac M. V-ATPase functions in normal and disease processes. Pflugers Arch 2009 457 : 589 598.
    • (2009) Pflugers Arch , vol.457 , pp. 589-598
    • Hinton, A.1    Bond, S.2    Forgac, M.3
  • 41
    • 67349286986 scopus 로고    scopus 로고
    • Small interfering RNA targeting the subunit ATP6L of proton pump V-ATPase overcomes chemoresistance of breast cancer cells
    • You H, Jin J, Shu H et al. Small interfering RNA targeting the subunit ATP6L of proton pump V-ATPase overcomes chemoresistance of breast cancer cells. Cancer Lett 2009 280 : 110 119.
    • (2009) Cancer Lett , vol.280 , pp. 110-119
    • You, H.1    Jin, J.2    Shu, H.3
  • 43
    • 0036481562 scopus 로고    scopus 로고
    • +)-ATPases - Nature's most versatile proton pumps
    • DOI 10.1038/nrm729
    • +)-ATPases - nature's most versatile proton pumps. Nat Rev Mol Cell Biol 2002 3 : 94 103. (Pubitemid 37237147)
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , Issue.2 , pp. 94-103
    • Nishi, T.1    Forgac, M.2
  • 44
    • 33746851956 scopus 로고    scopus 로고
    • Tumor metastasis: Mechanistic insights and clinical challenges
    • DOI 10.1038/nm1469, PII NM1469
    • Steeg PS. Tumor metastasis: mechanistic insights and clinical challenges. Nat Med 2006 12 : 895 904. (Pubitemid 44175140)
    • (2006) Nature Medicine , vol.12 , Issue.8 , pp. 895-904
    • Steeg, P.S.1
  • 45
    • 33751252276 scopus 로고    scopus 로고
    • Cancer Metastasis: Building a Framework
    • DOI 10.1016/j.cell.2006.11.001, PII S0092867406014140
    • Gupta GP, Massague J. Cancer metastasis: building a framework. Cell 2006 127 : 679 695. (Pubitemid 44781029)
    • (2006) Cell , vol.127 , Issue.4 , pp. 679-695
    • Gupta, G.P.1    Massague, J.2
  • 46
    • 23044467723 scopus 로고    scopus 로고
    • The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump
    • DOI 10.1158/0008-5472.CAN-04-3822
    • Lu X, Qin W, Li J et al. The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump. Cancer Res 2005 65 : 6843 6849. (Pubitemid 41060723)
    • (2005) Cancer Research , vol.65 , Issue.15 , pp. 6843-6849
    • Lu, X.1    Qin, W.2    Li, J.3    Tan, N.4    Pan, D.5    Zhang, H.6    Xie, L.7    Yao, G.8    Shu, H.9    Yao, M.10    Wan, D.11    Gu, J.12    Yang, S.13
  • 48
    • 18544379480 scopus 로고    scopus 로고
    • Enhanced expression of the human vacuolar H+-ATPase c subunit gene (ATP6L) in response to anticancer agents
    • Torigoe T, Izumi H, Ishiguchi H et al. Enhanced expression of the human vacuolar H+-ATPase c subunit gene (ATP6L) in response to anticancer agents. J Biol Chem 2002 277 : 36534 36543.
    • (2002) J Biol Chem , vol.277 , pp. 36534-36543
    • Torigoe, T.1    Izumi, H.2    Ishiguchi, H.3
  • 49
    • 0642334333 scopus 로고    scopus 로고
    • An overview of proton pump inhibitors
    • Der G. An overview of proton pump inhibitors. Gastroenterol Nurs 2003 26 : 182 190.
    • (2003) Gastroenterol Nurs , vol.26 , pp. 182-190
    • Der, G.1
  • 50
    • 0035666105 scopus 로고    scopus 로고
    • Replacement of oral proton pump inhibitors with intravenous pantoprazole to effectively control gastric acid hypersecretion in patients with Zollinger-Ellison syndrome
    • DOI 10.1016/S0002-9270(01)03887-4, PII S0002927001038874
    • Metz DC, Forsmark C, Lew EA et al. Replacement of oral proton pump inhibitors with intravenous pantoprazole to effectively control gastric acid hypersecretion in patients with Zollinger-Ellison syndrome. Am J Gastroenterol 2001 96 : 3274 3280. (Pubitemid 34016648)
    • (2001) American Journal of Gastroenterology , vol.96 , Issue.12 , pp. 3274-3280
    • Metz, D.C.1    Forsmark, C.2    Lew, E.A.3    Starr, J.A.4    Soffer, E.F.5    Bochenek, W.6    Pisegna, J.R.7
  • 51
    • 0036114397 scopus 로고    scopus 로고
    • Effect of pantoprazole versus other proton pump inhibitors on 24-hour intragastric pH and basal acid output in Zollinger-Ellison syndrome
    • Ramdani A, Mignon M, Samoyeau R. Effect of pantoprazole versus other proton pump inhibitors on 24-hour intragastric pH and basal acid output in Zollinger-Ellison syndrome. Gastroenterol Clin Biol 2002 26 : 355 359. (Pubitemid 34555809)
    • (2002) Gastroenterologie Clinique et Biologique , vol.26 , Issue.4 , pp. 355-359
    • Ramdani, A.1    Mignon, M.2    Samoyeau, R.3
  • 52
    • 69249211007 scopus 로고    scopus 로고
    • Effects and mechanisms of proton pump inhibitors as a novel chemosensitizer on human gastric adenocarcinoma (SGC7901) cells
    • Chen M, Zou X, Luo H et al. Effects and mechanisms of proton pump inhibitors as a novel chemosensitizer on human gastric adenocarcinoma (SGC7901) cells. Cell Biol Int 2009 33 : 1008 1019.
    • (2009) Cell Biol Int , vol.33 , pp. 1008-1019
    • Chen, M.1    Zou, X.2    Luo, H.3
  • 53
    • 4344679819 scopus 로고    scopus 로고
    • Treatment advances in adult Burkitt lymphoma and leukemia
    • DOI 10.1097/00001622-200409000-00003
    • Kasamon YL, Swinnen LJ. Treatment advances in adult Burkitt lymphoma and leukemia. Curr Opin Oncol 2004 16 : 429 435. (Pubitemid 39159169)
    • (2004) Current Opinion in Oncology , vol.16 , Issue.5 , pp. 429-435
    • Kasamon, Y.L.1    Swinnen, L.J.2
  • 54
    • 0036595208 scopus 로고    scopus 로고
    • Current chemotherapy protocols for childhood acute lymphoblastic leukemia induce loss of humoral immunity to viral vaccination antigens
    • Nilsson A, De Milito A, Engstrom P et al. Current chemotherapy protocols for childhood acute lymphoblastic leukemia induce loss of humoral immunity to viral vaccination antigens. Pediatrics 2002 109 : e91.
    • (2002) Pediatrics , vol.109 , pp. 91
    • Nilsson, A.1    De Milito, A.2    Engstrom, P.3
  • 58
    • 77950497624 scopus 로고    scopus 로고
    • PH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity
    • Oct 28.
    • De Milito A, Canese R, Marino ML et al. pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity. Int J Cancer 2009 Oct 28.
    • (2009) Int J Cancer
    • De Milito, A.1    Canese, R.2    Marino, M.L.3
  • 59
    • 25844528025 scopus 로고    scopus 로고
    • The role of disturbed pH dynamics and the Na+/H exchanger in metastasis
    • Cardone RA, Casavola V, Reshkin SJ. The role of disturbed pH dynamics and the Na+/H exchanger in metastasis. Nat Rev Cancer 2005 5 : 786 795.
    • (2005) Nat Rev Cancer , vol.5 , pp. 786-795
    • Cardone, R.A.1    Casavola, V.2    Reshkin, S.J.3
  • 61
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
    • DOI 10.1126/science.1067100
    • Coussens LM, Fingleton B, Matrisian LM. Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 2002 295 : 2387 2392. (Pubitemid 34270240)
    • (2002) Science , vol.295 , Issue.5564 , pp. 2387-2392
    • Coussens, L.M.1    Fingleton, B.2    Matrisian, L.M.3
  • 62
    • 0034646631 scopus 로고    scopus 로고
    • A rationalization of the acidic pH dependence for stromelysin-1 (matrix metalloproteinase-3) catalysis and inhibition
    • Johnson LL, Pavlovsky AG, Johnson AR et al. A rationalization of the acidic pH dependence for stromelysin-1 (matrix metalloproteinase-3) catalysis and inhibition. J Biol Chem 2000 275 : 11026 11033.
    • (2000) J Biol Chem , vol.275 , pp. 11026-11033
    • Johnson, L.L.1    Pavlovsky, A.G.2    Johnson, A.R.3
  • 63
    • 42949155409 scopus 로고    scopus 로고
    • Chronic metabolic acidosis may be the cause of cachexia: Body fluid pH correction may be an effective therapy
    • DOI 10.1016/j.mehy.2007.11.007, PII S0306987707006457
    • Drochioiu G. Chronic metabolic acidosis may be the cause of cachexia: body fluid pH correction may be an effective therapy. Med Hypotheses 2008 70 : 1167 1173. (Pubitemid 351614954)
    • (2008) Medical Hypotheses , vol.70 , Issue.6 , pp. 1167-1173
    • Drochioiu, G.1
  • 66
    • 65549166946 scopus 로고    scopus 로고
    • Bicarbonate increases tumor pH and inhibits spontaneous metastases
    • Robey IF, Baggett BK, Kirkpatrick ND et al. Bicarbonate increases tumor pH and inhibits spontaneous metastases. Cancer Res 2009 69 : 2260 2268.
    • (2009) Cancer Res , vol.69 , pp. 2260-2268
    • Robey, I.F.1    Baggett, B.K.2    Kirkpatrick, N.D.3
  • 67
    • 65549170684 scopus 로고    scopus 로고
    • The potential role of systemic buffers in reducing intratumoral extracellular pH and acid-mediated invasion
    • Silva AS, Yunes JA, Gillies RJ, Gatenby RA. The potential role of systemic buffers in reducing intratumoral extracellular pH and acid-mediated invasion. Cancer Res 2009 69 : 2677 2684.
    • (2009) Cancer Res , vol.69 , pp. 2677-2684
    • Silva, A.S.1    Yunes, J.A.2    Gillies, R.J.3    Gatenby, R.A.4
  • 68
    • 56949105019 scopus 로고    scopus 로고
    • Recent progress in tumor pH targeting nanotechnology
    • Lee ES, Gao Z, Bae YH. Recent progress in tumor pH targeting nanotechnology. J Control Release 2008 132 : 164 170.
    • (2008) J Control Release , vol.132 , pp. 164-170
    • Lee, E.S.1    Gao, Z.2    Bae, Y.H.3
  • 69
    • 65949122547 scopus 로고    scopus 로고
    • Suppression of human solid tumor growth in mice by intratumor and systemic inoculation of histidine-rich and pH-dependent host defense-like lytic peptides
    • Makovitzki A, Fink A, Shai Y. Suppression of human solid tumor growth in mice by intratumor and systemic inoculation of histidine-rich and pH-dependent host defense-like lytic peptides. Cancer Res 2009 69 : 3458 3463.
    • (2009) Cancer Res , vol.69 , pp. 3458-3463
    • Makovitzki, A.1    Fink, A.2    Shai, Y.3
  • 70
    • 0343052850 scopus 로고    scopus 로고
    • Basis for the selective antibacterial activity in vitro of proton pump inhibitors against Helicobacter spp.
    • Sjøstrøm JE, Kühler T, Larsson H. Basis for the selective antibacterial activity in vitro of proton pump inhibitors against Helicobacter spp. Antimicrob Agents Chemother 1997 41 : 1797 1801. (Pubitemid 27339890)
    • (1997) Antimicrobial Agents and Chemotherapy , vol.41 , Issue.8 , pp. 1797-1801
    • Sjostrom, J.-E.1    Kuhler, T.2    Larsson, H.3
  • 72
    • 67049145610 scopus 로고    scopus 로고
    • Omeprazole antagonizes virulence and inflammation in Salmonella enterica-infected RAW264.7 cells
    • Puiac S, Negrea A, Richter-Dahlfors A, Plant L, Rhen M. Omeprazole antagonizes virulence and inflammation in Salmonella enterica-infected RAW264.7 cells. Antimicrob Agents Chemother 2009 53 : 2402 2409.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 2402-2409
    • Puiac, S.1    Negrea, A.2    Richter-Dahlfors, A.3    Plant, L.4    Rhen, M.5
  • 74
    • 73849124226 scopus 로고    scopus 로고
    • The human homologue of Dictyostelium discoideum phg1A is expressed by human metastatic melanoma cells
    • Lozupone F, Perdicchio M, Brambilla D et al. The human homologue of Dictyostelium discoideum phg1A is expressed by human metastatic melanoma cells. EMBO Rep 2009 10 : 1348 1354.
    • (2009) EMBO Rep , vol.10 , pp. 1348-1354
    • Lozupone, F.1    Perdicchio, M.2    Brambilla, D.3
  • 75
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer 2004 4 : 891 899.
    • (2004) Nat Rev Cancer , vol.4 , pp. 891-899
    • Gatenby, R.A.1    Gillies, R.J.2
  • 76
    • 0025916864 scopus 로고
    • Involvement of vacuolar H(+)-adenosine triphosphatase activity in multidrug resistance in HL60 cells
    • Marquardt D, Center MS. Involvement of vacuolar H(+)-adenosine triphosphatase activity in multidrug resistance in HL60 cells. J Natl Cancer Inst 1991 83 : 1098 1102.
    • (1991) J Natl Cancer Inst , vol.83 , pp. 1098-1102
    • Marquardt, D.1    Center, M.S.2
  • 77
    • 57449115616 scopus 로고    scopus 로고
    • Tumor metabolism: Cancer cells give and take lactate
    • Semenza GL. Tumor metabolism: cancer cells give and take lactate. J Clin Invest 2008 118 : 3835 3837.
    • (2008) J Clin Invest , vol.118 , pp. 3835-3837
    • Semenza, G.L.1
  • 78
    • 42449102301 scopus 로고    scopus 로고
    • +-adenosine triphosphatase by N-methyl-N'-nitro-N-nitrosoguanidine in the gastric epithelial RGM-1 cell line
    • +-adenosine triphosphatase by N-methyl-N'-nitro-N-nitrosoguanidine in the gastric epithelial RGM-1 cell line. In Vitro Cell Dev Biol Anim. 2008 44 : 26 30.
    • (2008) Vitro Cell Dev Biol Anim. , vol.44 , pp. 26-30
    • Shimokawa, O.1    Matsui, H.2    Nagano, Y.3
  • 79
    • 0026425695 scopus 로고
    • Subcellular distribution of daunorubicin in P-glycoprotein-positive and -negative drug-resistant cell lines using laser-assisted confocal microscopy
    • Gervasoni JE Jr., Fields SZ, Krishna S, et al. Subcellular distribution of daunorubicin in P-glycoprotein-positive and -negative drug-resistant cell lines using laser-assisted confocal microscopy. Cancer Res 1991 51 : 4955 4963.
    • (1991) Cancer Res , vol.51 , pp. 4955-4963
    • Gervasoni, Jr.J.E.1    Fields, S.Z.2    Krishna, S.3
  • 80
    • 0023785754 scopus 로고
    • The effect of lysosomotropic agents and secretory inhibitors on anthracycline retention and activity in multiple drug-resistant cells
    • Klohs WD, Steinkampf RW. The effect of lysosomotropic agents and secretory inhibitors on anthracycline retention and activity in multiple drug-resistant cells. Mol Pharmacol 1988 34 : 180 185.
    • (1988) Mol Pharmacol , vol.34 , pp. 180-185
    • Klohs, W.D.1    Steinkampf, R.W.2
  • 81
    • 0036594889 scopus 로고    scopus 로고
    • Regulation of intracellular pH in human melanoma: Potential therapeutic implications
    • Wahl ML, Owen JA, Burd R, et al. Regulation of intracellular pH in human melanoma: potential therapeutic implications. Mol Cancer Ther 2002 1 : 617 628.
    • (2002) Mol Cancer Ther , vol.1 , pp. 617-628
    • Wahl, M.L.1    Owen, J.A.2    Burd, R.3
  • 82
    • 36948999655 scopus 로고    scopus 로고
    • Erratum (Retracted Article): Blockage of intracellular proton extrusion with proton pump inhibitor induces apoptosis in gastric cancer (Cancer Science)
    • DOI 10.1111/j.1349-7006.2007.00642.x
    • Yeo M, Kim DK, Park HJ, Cho SW, Cheong JY, Lee KJ. Blockage of intracellular proton extrusion with proton extrusions with proton pump inhibitor induces apoptosis in gastric cancer. Cancer Sci 2008 99 : 185. (Pubitemid 350239049)
    • (2008) Cancer Science , vol.99 , Issue.1 , pp. 185
    • Yeo, M.1    Kim, D.-K.2    Park, H.-J.3    Cho, S.-W.4    Cheong, J.Y.5    Lee, K.J.6
  • 83
    • 52449104060 scopus 로고    scopus 로고
    • The proton pump inhibitor inhibits cell growth and induces apoptosis in human hepatoblastoma
    • Morimura T, Fujita K, Akita M, Nagashima M, Satomi A. The proton pump inhibitor inhibits cell growth and induces apoptosis in human hepatoblastoma. Pediatr Surg Int 2008 24 : 1087 1094.
    • (2008) Pediatr Surg Int , vol.24 , pp. 1087-1094
    • Morimura, T.1    Fujita, K.2    Akita, M.3    Nagashima, M.4    Satomi, A.5


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