메뉴 건너뛰기




Volumn 7, Issue , 2012, Pages 1551-1572

Inhaled chemotherapy in lung cancer: Future concept of nanomedicine

Author keywords

Carriers; Inhaled chemotherapy; Transducers

Indexed keywords

ABC TRANSPORTER; CARBOHYDRATE DERIVATIVE; CARBOPLATIN; CISPLATIN; CYCLOSPORIN A; DOXORUBICIN; FLUOROURACIL; GEMCITABINE; LIPOSOME; MULTIDRUG RESISTANCE PROTEIN; NANOPARTICLE; ORGANIC CATION TRANSPORTER; PACLITAXEL; PEPTIDE TRANSPORTER 1; PEPTIDE TRANSPORTER 2; POLYMER; RUBITECAN; ANTINEOPLASTIC AGENT; CARRIER PROTEIN; DRUG CARRIER;

EID: 84865760040     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S29997     Document Type: Review
Times cited : (169)

References (255)
  • 2
    • 36049015455 scopus 로고    scopus 로고
    • Phase II study of low-dose paclitaxel and cisplatin in combination with split-course concomitant twice-daily reirradiation in recurrent squamous cell carcinoma of the head and neck: Results of Radiation Therapy Oncology Group Protocol 9911
    • Langer CJ, Harris J, Horwitz EM, et al. Phase II study of low-dose paclitaxel and cisplatin in combination with split-course concomitant twice-daily reirradiation in recurrent squamous cell carcinoma of the head and neck: results of Radiation Therapy Oncology Group Protocol 9911 J Clin Oncol. 2007;25(30):4800-4805.
    • (2007) J Clin Oncol. , vol.25 , Issue.30 , pp. 4800-4805
    • Langer, C.J.1    Harris, J.2    Horwitz, E.M.3
  • 3
    • 49249095150 scopus 로고    scopus 로고
    • Addressing the current challenges of non-small-cell lung cancer clinical trial accrual
    • Curran WJ Jr, Schiller JH, Wolkin AC, Comis RL. Addressing the current challenges of non-small-cell lung cancer clinical trial accrual. Clin Lung Cancer. 2008;9(4):222-226.
    • (2008) Clin Lung Cancer. , vol.9 , Issue.4 , pp. 222-226
    • Curran Jr., W.J.1    Schiller, J.H.2    Wolkin, A.C.3    Comis, R.L.4
  • 4
    • 43049111427 scopus 로고    scopus 로고
    • Restrictive eligibility limits access to newer therapies in non-small-cell lung cancer: The implications of Eastern Cooperative Oncology Group 4599
    • Somer RA, Sherman E, Langer CJ. Restrictive eligibility limits access to newer therapies in non-small-cell lung cancer: the implications of Eastern Cooperative Oncology Group 4599. Clin Lung Cancer. 2008;9(2):102-105.
    • (2008) Clin Lung Cancer. , vol.9 , Issue.2 , pp. 102-105
    • Somer, R.A.1    Sherman, E.2    Langer, C.J.3
  • 5
    • 34250351911 scopus 로고    scopus 로고
    • Toward therapies tailored to patient characteristics
    • Novello S, Longo M, Levra MG. Toward therapies tailored to patient characteristics. J Thorac Oncol. 2007;2(Suppl 5):S38-S41.
    • (2007) J Thorac Oncol. , vol.2 , Issue.SUPPL. 5
    • Novello, S.1    Longo, M.2    Levra, M.G.3
  • 6
    • 84857076353 scopus 로고    scopus 로고
    • Targeted therapy in lung cancer: Lessons learned from past experiences
    • Subramanian J, Waqar SN, Govindan R. Targeted therapy in lung cancer: lessons learned from past experiences. J Thorac Oncol. 2011; 6(11 Suppl 4):S1786-S1788.
    • (2011) J Thorac Oncol. , vol.6 , Issue.11 SUPPL. 4
    • Subramanian, J.1    Waqar, S.N.2    Govindan, R.3
  • 7
    • 83955162209 scopus 로고    scopus 로고
    • Relationships between cisplatin-induced adducts and DNA strand-breaks, mutation and recombination in vivo in somatic cells of Drosophila melanogaster, under different conditions of nucleotide excision repair
    • Garcia Sar D, Aguado L, Montes Bayon M, et al. Relationships between cisplatin-induced adducts and DNA strand-breaks, mutation and recombination in vivo in somatic cells of Drosophila melanogaster, under different conditions of nucleotide excision repair. Mutat Res. 2012;741(1-2):81-88.
    • (2012) Mutat Res. , vol.741 , Issue.1-2 , pp. 81-88
    • Garcia Sar, D.1    Aguado, L.2    Montes Bayon, M.3
  • 8
    • 80054741764 scopus 로고    scopus 로고
    • Phase II study of topotecan with cisplatin in Japanese patients with small cell lung cancer
    • Hosomi Y, Shibuya M, Niho S, et al. Phase II study of topotecan with cisplatin in Japanese patients with small cell lung cancer. Anticancer Res. 2011;31(10):3449-3456.
    • (2011) Anticancer Res. , vol.31 , Issue.10 , pp. 3449-3456
    • Hosomi, Y.1    Shibuya, M.2    Niho, S.3
  • 9
    • 37349068491 scopus 로고    scopus 로고
    • The International Association for the Study of Lung Cancer lung cancer staging project: Proposals regarding the clinical staging of small cell lung cancer in the forthcoming (seventh) edition of the tumor, node, metastasis classification for lung cancer
    • Shepherd FA, Crowley J, Van Houtte P, et al. The International Association for the Study of Lung Cancer lung cancer staging project: proposals regarding the clinical staging of small cell lung cancer in the forthcoming (seventh) edition of the tumor, node, metastasis classification for lung cancer. J Thorac Oncol. 2007;2(12):1067-1077.
    • (2007) J Thorac Oncol. , vol.2 , Issue.12 , pp. 1067-1077
    • Shepherd, F.A.1    Crowley, J.2    van Houtte, P.3
  • 10
    • 80054758751 scopus 로고    scopus 로고
    • Paclitaxel and TRAIL synergize to kill paclitaxel-resistant small cell lung cancer cells through a caspase-independent mechanism mediated through AIF
    • Hunter TB, Manimala NJ, Luddy KA, Catlin T, Antonia SJ. Paclitaxel and TRAIL synergize to kill paclitaxel-resistant small cell lung cancer cells through a caspase-independent mechanism mediated through AIF. Anticancer Res. 2011;31(10):3193-3204.
    • (2011) Anticancer Res. , vol.31 , Issue.10 , pp. 3193-3204
    • Hunter, T.B.1    Manimala, N.J.2    Luddy, K.A.3    Catlin, T.4    Antonia, S.J.5
  • 11
    • 0037050352 scopus 로고    scopus 로고
    • Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
    • Schiller JH, Harrington D, Belani CP, et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med. 2002;346(2):92-98.
    • (2002) N Engl J Med. , vol.346 , Issue.2 , pp. 92-98
    • Schiller, J.H.1    Harrington, D.2    Belani, C.P.3
  • 12
    • 33746491709 scopus 로고    scopus 로고
    • Drug penetration in solid tumours
    • Minchinton AI, Tannock IF. Drug penetration in solid tumours. Nat Rev Cancer. 2006;6(8):583-592.
    • (2006) Nat Rev Cancer. , vol.6 , Issue.8 , pp. 583-592
    • Minchinton, A.I.1    Tannock, I.F.2
  • 13
    • 33645450153 scopus 로고    scopus 로고
    • Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer: A randomized trial of efficacy, quality of life, and molecular markers (CALGB 9481)
    • Kemeny NE, Niedzwiecki D, Hollis DR, et al. Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer: a randomized trial of efficacy, quality of life, and molecular markers (CALGB 9481). J Clin Oncol. 2006;24(9):1395-1403.
    • (2006) J Clin Oncol. , vol.24 , Issue.9 , pp. 1395-1403
    • Kemeny, N.E.1    Niedzwiecki, D.2    Hollis, D.R.3
  • 14
    • 30044438368 scopus 로고    scopus 로고
    • Intraperitoneal cisplatin and paclitaxel in ovarian cancer
    • Armstrong DK, Bundy B, Wenzel L, et al. Intraperitoneal cisplatin and paclitaxel in ovarian cancer. N Engl J Med. 2006;354(1):34-43.
    • (2006) N Engl J Med. , vol.354 , Issue.1 , pp. 34-43
    • Armstrong, D.K.1    Bundy, B.2    Wenzel, L.3
  • 15
    • 1042291304 scopus 로고    scopus 로고
    • Recent advances in brain tumor therapy: Local intracerebral drug delivery by polymers
    • Guerin C, Olivi A, Weingart JD, Lawson HC, Brem H. Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers. Invest New Drugs. 2004;22(1):27-37.
    • (2004) Invest New Drugs. , vol.22 , Issue.1 , pp. 27-37
    • Guerin, C.1    Olivi, A.2    Weingart, J.D.3    Lawson, H.C.4    Brem, H.5
  • 17
    • 0035977201 scopus 로고    scopus 로고
    • A phase I and pharmacokinetic study of intraperitoneal topotecan
    • Hofstra LS, Bos AM, de Vries EG, et al. A phase I and pharmacokinetic study of intraperitoneal topotecan. Br J Cancer. 2001;85(11):1627-1633.
    • (2001) Br J Cancer. , vol.85 , Issue.11 , pp. 1627-1633
    • Hofstra, L.S.1    Bos, A.M.2    de Vries, E.G.3
  • 18
    • 0032945536 scopus 로고    scopus 로고
    • Bronchial arterial infusion is an effective therapeutic modality for centrally located early-stage lung cancer: Results of a pilot study
    • Osaki T, Hanagiri T, Nakanishi R, Yoshino I, Taga S, Yasumoto K. Bronchial arterial infusion is an effective therapeutic modality for centrally located early-stage lung cancer: results of a pilot study. Chest. 1999;115(5):1424-1428.
    • (1999) Chest. , vol.115 , Issue.5 , pp. 1424-1428
    • Osaki, T.1    Hanagiri, T.2    Nakanishi, R.3    Yoshino, I.4    Taga, S.5    Yasumoto, K.6
  • 19
    • 0036797258 scopus 로고    scopus 로고
    • Neoplastic pericardial effusion. Efficacy and safety of intrapericardial treatment with cisplatin
    • Maisch B, Ristic AD, Pankuweit S, Neubauer A, Moll R. Neoplastic pericardial effusion. Efficacy and safety of intrapericardial treatment with cisplatin. Eur Heart J. 2002;23(20):1625-1631.
    • (2002) Eur Heart J. , vol.23 , Issue.20 , pp. 1625-1631
    • Maisch, B.1    Ristic, A.D.2    Pankuweit, S.3    Neubauer, A.4    Moll, R.5
  • 20
    • 0022580918 scopus 로고
    • Cisplatin administered by the intracavitary route as treatment for malignant mesothelioma
    • Markman M, Cleary S, Pfeifle C, Howell SB. Cisplatin administered by the intracavitary route as treatment for malignant mesothelioma. Cancer. 1986;58(1):18-21.
    • (1986) Cancer. , vol.58 , Issue.1 , pp. 18-21
    • Markman, M.1    Cleary, S.2    Pfeifle, C.3    Howell, S.B.4
  • 21
    • 0026036043 scopus 로고
    • Intrapleural cisplatin and cytarabine in the management of malignant pleural effusions: A Lung Cancer Study Group trial
    • Rusch VW, Figlin R, Godwin D, Piantadosi S. Intrapleural cisplatin and cytarabine in the management of malignant pleural effusions: a Lung Cancer Study Group trial. J Clin Oncol. 1991;9(2):313-319.
    • (1991) J Clin Oncol. , vol.9 , Issue.2 , pp. 313-319
    • Rusch, V.W.1    Figlin, R.2    Godwin, D.3    Piantadosi, S.4
  • 22
    • 0036172369 scopus 로고    scopus 로고
    • Intratumoral cancer chemotherapy and immunotherapy: Opportunities for nonsystemic preoperative drug delivery
    • Goldberg EP, Hadba AR, Almond BA, Marotta JS. Intratumoral cancer chemotherapy and immunotherapy: opportunities for nonsystemic preoperative drug delivery. J Pharm Pharmacol. 2002;54(2): 159-180.
    • (2002) J Pharm Pharmacol. , vol.54 , Issue.2 , pp. 159-180
    • Goldberg, E.P.1    Hadba, A.R.2    Almond, B.A.3    Marotta, J.S.4
  • 23
    • 1542619545 scopus 로고    scopus 로고
    • Phase 2 study of intratumoral cisplatin and epinephrine treatment for locally recurrent head and neck tumors
    • Duvillard C, Romanet P, Cosmidis A, Beaudouin N, Chauffert B. Phase 2 study of intratumoral cisplatin and epinephrine treatment for locally recurrent head and neck tumors. Ann Otol Rhinol Laryngol. 2004; 113(3 Pt 1):229-233.
    • (2004) Ann Otol Rhinol Laryngol. , vol.113 , Issue.3 PART 1 , pp. 229-233
    • Duvillard, C.1    Romanet, P.2    Cosmidis, A.3    Beaudouin, N.4    Chauffert, B.5
  • 24
    • 0344513087 scopus 로고    scopus 로고
    • Pulmonary drug delivery. Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications
    • Labiris NR, Dolovich MB. Pulmonary drug delivery. Part I: physiological factors affecting therapeutic effectiveness of aerosolized medications. Br J Clin Pharmacol. 2003;56(6):588-599.
    • (2003) Br J Clin Pharmacol. , vol.56 , Issue.6 , pp. 588-599
    • Labiris, N.R.1    Dolovich, M.B.2
  • 25
    • 33644627889 scopus 로고    scopus 로고
    • The expanding role of aerosols in systemic drug delivery, gene therapy, and vaccination
    • Laube BL. The expanding role of aerosols in systemic drug delivery, gene therapy, and vaccination. Respir Care. 2005;50(9):1161-1176.
    • (2005) Respir Care. , vol.50 , Issue.9 , pp. 1161-1176
    • Laube, B.L.1
  • 26
    • 82555185048 scopus 로고    scopus 로고
    • Improved treatment response to dornase alfa in cystic fibrosis patients using controlled inhalation
    • Bakker EM, Volpi S, Salonini E, et al. Improved treatment response to dornase alfa in cystic fibrosis patients using controlled inhalation. Eur Respir J. 2011;38(6):1328-1335.
    • (2011) Eur Respir J. , vol.38 , Issue.6 , pp. 1328-1335
    • Bakker, E.M.1    Volpi, S.2    Salonini, E.3
  • 27
    • 80355127141 scopus 로고    scopus 로고
    • Inhaled dry powder mannitol in cystic fibrosis: An efficacy and safety study
    • Bilton D, Robinson P, Cooper P, et al. Inhaled dry powder mannitol in cystic fibrosis: an efficacy and safety study. Eur Respir J. 2011;38(5): 1071-1080.
    • (2011) Eur Respir J. , vol.38 , Issue.5 , pp. 1071-1080
    • Bilton, D.1    Robinson, P.2    Cooper, P.3
  • 28
    • 78650968903 scopus 로고    scopus 로고
    • Aerosol delivery of small hairpin osteopontin blocks pulmonary metastasis of breast cancer in mice
    • Yu KN, Minai-Tehrani A, Chang SH, et al. Aerosol delivery of small hairpin osteopontin blocks pulmonary metastasis of breast cancer in mice. PLoS One. 2010;5(12):e15623.
    • (2010) PLoS One. , vol.5 , Issue.12
    • Yu, K.N.1    Minai-Tehrani, A.2    Chang, S.H.3
  • 31
    • 0020773403 scopus 로고
    • New chemotherapeutic method for the treatment of tracheal and bronchial cancers-nebulization chemotherapy
    • Japanese
    • Tatsumura T, Yamamoto K, Murakami A, Tsuda M, Sugiyama S. New chemotherapeutic method for the treatment of tracheal and bronchial cancers-nebulization chemotherapy. Gan No Rinsho. 1983;29(7): 765-770. Japanese.
    • (1983) Gan No Rinsho. , vol.29 , Issue.7 , pp. 765-770
    • Tatsumura, T.1    Yamamoto, K.2    Murakami, A.3    Tsuda, M.4    Sugiyama, S.5
  • 32
    • 0027421114 scopus 로고
    • Further study of nebulisation chemotherapy, a new chemotherapeutic method in the treatment of lung carcinomas: Fundamental and clinical
    • Tatsumura T, Koyama S, Tsujimoto M, Kitagawa M, Kagamimori S. Further study of nebulisation chemotherapy, a new chemotherapeutic method in the treatment of lung carcinomas: fundamental and clinical. Br J Cancer. 1993;68(6):1146-1149.
    • (1993) Br J Cancer. , vol.68 , Issue.6 , pp. 1146-1149
    • Tatsumura, T.1    Koyama, S.2    Tsujimoto, M.3    Kitagawa, M.4    Kagamimori, S.5
  • 33
    • 0042129873 scopus 로고    scopus 로고
    • Paclitaxel (Taxol) and taxoid derivates for lung cancer treatment: Potential for aerosol delivery
    • Gautam A, Koshkina N. Paclitaxel (Taxol) and taxoid derivates for lung cancer treatment: potential for aerosol delivery. Curr Cancer Drug Targets. 2003;3(4):287-296.
    • (2003) Curr Cancer Drug Targets. , vol.3 , Issue.4 , pp. 287-296
    • Gautam, A.1    Koshkina, N.2
  • 34
    • 0032853556 scopus 로고    scopus 로고
    • Inhalation chemotherapy for macroscopic primary or metastatic lung tumors: Proof of principle using dogs with spontaneously occurring tumors as a model
    • Hershey AE, Kurzman ID, Forrest LJ, et al. Inhalation chemotherapy for macroscopic primary or metastatic lung tumors: proof of principle using dogs with spontaneously occurring tumors as a model. Clin Cancer Res. 1999;5(9):2653-2659.
    • (1999) Clin Cancer Res. , vol.5 , Issue.9 , pp. 2653-2659
    • Hershey, A.E.1    Kurzman, I.D.2    Forrest, L.J.3
  • 35
    • 1942533024 scopus 로고    scopus 로고
    • Cyclosporin A aerosol improves the anticancer effect of paclitaxel aerosol in mice
    • Koshkina NV, Golunski E, Roberts LE, Gilbert BE, Knight V. Cyclosporin A aerosol improves the anticancer effect of paclitaxel aerosol in mice. J Aerosol Med. 2004;17(1):7-14.
    • (2004) J Aerosol Med. , vol.17 , Issue.1 , pp. 7-14
    • Koshkina, N.V.1    Golunski, E.2    Roberts, L.E.3    Gilbert, B.E.4    Knight, V.5
  • 36
    • 0021256244 scopus 로고
    • Pharmacokinetics of doxorubicin in isolated lung of dogs and humans perfused in vivo
    • Minchin RF, Johnston MR, Aiken MA, Boyd MR. Pharmacokinetics of doxorubicin in isolated lung of dogs and humans perfused in vivo. J Pharmacol Exp Ther. 1984;229(1):193-198.
    • (1984) J Pharmacol Exp Ther. , vol.229 , Issue.1 , pp. 193-198
    • Minchin, R.F.1    Johnston, M.R.2    Aiken, M.A.3    Boyd, M.R.4
  • 37
    • 77951011298 scopus 로고    scopus 로고
    • Phase I/II study of inhaled doxorubicin combined with platinum-based therapy for advanced non-small cell lung cancer
    • Otterson GA, Villalona-Calero MA, Hicks W, et al. Phase I/II study of inhaled doxorubicin combined with platinum-based therapy for advanced non-small cell lung cancer. Clin Cancer Res. 2010;16(8):2466-2473.
    • (2010) Clin Cancer Res. , vol.16 , Issue.8 , pp. 2466-2473
    • Otterson, G.A.1    Villalona-Calero, M.A.2    Hicks, W.3
  • 38
    • 27844562815 scopus 로고    scopus 로고
    • Spray-dried poly(D, L-lactide) microspheres containing carboplatin for veterinary use: In vitro and in vivo studies
    • Gavini E, Manunta L, Giua S, Achenza G, Giunchedi P. Spray-dried poly(D, L-lactide) microspheres containing carboplatin for veterinary use: in vitro and in vivo studies. AAPS Pharm Sci Tech. 2005;6(1):E108-E114.
    • (2005) AAPS Pharm Sci Tech. , vol.6 , Issue.1
    • Gavini, E.1    Manunta, L.2    Giua, S.3    Achenza, G.4    Giunchedi, P.5
  • 39
    • 0041629016 scopus 로고    scopus 로고
    • Targeting the lung: Preclinical and comparative evaluation of anticancer aerosols in dogs with naturally occurring cancers
    • Khanna C, Vail DM. Targeting the lung: preclinical and comparative evaluation of anticancer aerosols in dogs with naturally occurring cancers. Curr Cancer Drug Targets. 2003;3(4):265-273.
    • (2003) Curr Cancer Drug Targets. , vol.3 , Issue.4 , pp. 265-273
    • Khanna, C.1    Vail, D.M.2
  • 41
    • 54949096176 scopus 로고    scopus 로고
    • Feasibility and safety of targeted cisplatin delivery to a select lung lobe in dogs via the AeroProbe intracorporeal nebulization catheter
    • Selting K, Waldrep JC, Reinero C, et al. Feasibility and safety of targeted cisplatin delivery to a select lung lobe in dogs via the AeroProbe intracorporeal nebulization catheter. J Aerosol Med Pulm Drug Deliv. 2008;21(3):255-268.
    • (2008) J Aerosol Med Pulm Drug Deliv. , vol.21 , Issue.3 , pp. 255-268
    • Selting, K.1    Waldrep, J.C.2    Reinero, C.3
  • 42
    • 33750956761 scopus 로고    scopus 로고
    • Assessing a system to capture stray aerosol during inhalation of nebulized liposomal cisplatin
    • Wittgen BP, Kunst PW, Perkins WR, Lee JK, Postmus PE. Assessing a system to capture stray aerosol during inhalation of nebulized liposomal cisplatin. J Aerosol Med. 2006;19(3):385-391.
    • (2006) J Aerosol Med. , vol.19 , Issue.3 , pp. 385-391
    • Wittgen, B.P.1    Kunst, P.W.2    Perkins, W.R.3    Lee, J.K.4    Postmus, P.E.5
  • 43
    • 26844498016 scopus 로고    scopus 로고
    • Aerosol delivery of chemotherapy in an orthotopic model of lung cancer
    • Gagnadoux F, Pape AL, Lemarie E, et al. Aerosol delivery of chemotherapy in an orthotopic model of lung cancer. Eur Respir J. 2005;26(4): 657-661.
    • (2005) Eur Respir J. , vol.26 , Issue.4 , pp. 657-661
    • Gagnadoux, F.1    Pape, A.L.2    Lemarie, E.3
  • 44
    • 74349091948 scopus 로고    scopus 로고
    • Pulmonary targeting microparticulate camptothecin delivery system: Anticancer evaluation in a rat orthotopic lung cancer model
    • Chao P, Deshmukh M, Kutscher HL, et al. Pulmonary targeting microparticulate camptothecin delivery system: anticancer evaluation in a rat orthotopic lung cancer model. Anticancer Drugs. 2010;21(1):65-76.
    • (2010) Anticancer Drugs. , vol.21 , Issue.1 , pp. 65-76
    • Chao, P.1    Deshmukh, M.2    Kutscher, H.L.3
  • 45
    • 67349255031 scopus 로고    scopus 로고
    • The use of biotinylated-EGF-modified gelatin nanoparticle carrier to enhance cisplatin accumulation in cancerous lungs via inhalation
    • Tseng CL, Su WY, Yen KC, Yang KC, Lin FH. The use of biotinylated-EGF-modified gelatin nanoparticle carrier to enhance cisplatin accumulation in cancerous lungs via inhalation. Biomaterials. 2009;30(20): 3476-3485.
    • (2009) Biomaterials. , vol.30 , Issue.20 , pp. 3476-3485
    • Tseng, C.L.1    Su, W.Y.2    Yen, K.C.3    Yang, K.C.4    Lin, F.H.5
  • 46
    • 78149232478 scopus 로고    scopus 로고
    • Uptake of all-trans retinoic acid-containing aerosol by inhalation to lungs in a guinea pig model system-a pilot study
    • Schaffer MW, Roy SS, Mukherjee S, Ong DE, Das SK. Uptake of all-trans retinoic acid-containing aerosol by inhalation to lungs in a guinea pig model system-a pilot study. Exp Lung Res. 2010;36(10):593-601.
    • (2010) Exp Lung Res. , vol.36 , Issue.10 , pp. 593-601
    • Schaffer, M.W.1    Roy, S.S.2    Mukherjee, S.3    Ong, D.E.4    Das, S.K.5
  • 48
    • 70349335728 scopus 로고    scopus 로고
    • Lipid nanocapsules: Readyto-use nanovectors for the aerosol delivery of paclitaxel
    • Hureaux J, Lagarce F, Gagnadoux F, et al. Lipid nanocapsules: readyto-use nanovectors for the aerosol delivery of paclitaxel. Eur J Pharm Biopharm. 2009;73(2):239-246.
    • (2009) Eur J Pharm Biopharm. , vol.73 , Issue.2 , pp. 239-246
    • Hureaux, J.1    Lagarce, F.2    Gagnadoux, F.3
  • 49
    • 10044264288 scopus 로고    scopus 로고
    • Alpha-TEA plus cisplatin reduces human cisplatin-resistant ovarian cancer cell tumor burden and metastasis
    • Anderson K, Lawson KA, Simmons-Menchaca M, Sun L, Sanders BG, Kline K. Alpha-TEA plus cisplatin reduces human cisplatin-resistant ovarian cancer cell tumor burden and metastasis. Exp Biol Med (Maywood). 2004;229(11):1169-1176.
    • (2004) Exp Biol Med (Maywood). , vol.229 , Issue.11 , pp. 1169-1176
    • Anderson, K.1    Lawson, K.A.2    Simmons-Menchaca, M.3    Sun, L.4    Sanders, B.G.5    Kline, K.6
  • 50
    • 0034787791 scopus 로고    scopus 로고
    • Paclitaxel liposome aerosol treatment induces inhibition of pulmonary metastases in murine renal carcinoma model
    • Koshkina NV, Waldrep JC, Roberts LE, Golunski E, Melton S, Knight V. Paclitaxel liposome aerosol treatment induces inhibition of pulmonary metastases in murine renal carcinoma model. Clin Cancer Res. 2001;7(10):3258-3262.
    • (2001) Clin Cancer Res. , vol.7 , Issue.10 , pp. 3258-3262
    • Koshkina, N.V.1    Waldrep, J.C.2    Roberts, L.E.3    Golunski, E.4    Melton, S.5    Knight, V.6
  • 51
    • 77953766334 scopus 로고    scopus 로고
    • Inhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistance
    • Garbuzenko OB, Saad M, Pozharov VP, Reuhl KR, Mainelis G, Minko T. Inhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistance. Proc Natl Acad Sci U S A. 2010;107(23):10737-10742.
    • (2010) Proc Natl Acad Sci U S A. , vol.107 , Issue.23 , pp. 10737-10742
    • Garbuzenko, O.B.1    Saad, M.2    Pozharov, V.P.3    Reuhl, K.R.4    Mainelis, G.5    Minko, T.6
  • 52
    • 33947212925 scopus 로고    scopus 로고
    • Phase I study of inhaled doxorubicin for patients with metastatic tumors to the lungs
    • Otterson GA, Villalona-Calero MA, Sharma S, et al. Phase I study of inhaled doxorubicin for patients with metastatic tumors to the lungs. Clin Cancer Res. 2007;13(4):1246-1252.
    • (2007) Clin Cancer Res. , vol.13 , Issue.4 , pp. 1246-1252
    • Otterson, G.A.1    Villalona-Calero, M.A.2    Sharma, S.3
  • 53
    • 34247897230 scopus 로고    scopus 로고
    • Phase I study of aerosolized SLIT cisplatin in the treatment of patients with carcinoma of the lung
    • Wittgen BP, Kunst PW, van der Born K, et al. Phase I study of aerosolized SLIT cisplatin in the treatment of patients with carcinoma of the lung. Clin Cancer Res. 2007;13(8):2414-2421.
    • (2007) Clin Cancer Res. , vol.13 , Issue.8 , pp. 2414-2421
    • Wittgen, B.P.1    Kunst, P.W.2    van der Born, K.3
  • 54
    • 1942538547 scopus 로고    scopus 로고
    • Chemoprevention of cancer of the upper respiratory tract of the Syrian golden hamster by aerosol administration of difluoromethylornithine and 5-fluorouracil
    • Wattenberg LW, Wiedmann TS, Estensen RD. Chemoprevention of cancer of the upper respiratory tract of the Syrian golden hamster by aerosol administration of difluoromethylornithine and 5-fluorouracil. Cancer Res. 2004;64(7):2347-2349.
    • (2004) Cancer Res. , vol.64 , Issue.7 , pp. 2347-2349
    • Wattenberg, L.W.1    Wiedmann, T.S.2    Estensen, R.D.3
  • 56
    • 1842479077 scopus 로고    scopus 로고
    • Clinical evaluation of the delivery and safety of aerosolized liposomal 9-nitro-20(s)-camptothecin in patients with advanced pulmonary malignancies
    • Verschraegen CF, Gilbert BE, Loyer E, et al. Clinical evaluation of the delivery and safety of aerosolized liposomal 9-nitro-20(s)-camptothecin in patients with advanced pulmonary malignancies. Clin Cancer Res. 2004;10(7):2319-2326.
    • (2004) Clin Cancer Res. , vol.10 , Issue.7 , pp. 2319-2326
    • Verschraegen, C.F.1    Gilbert, B.E.2    Loyer, E.3
  • 57
    • 7744226289 scopus 로고    scopus 로고
    • Novel vitamin E analogue and 9-nitro-camptothecin administered as liposome aerosols decrease syngeneic mouse mammary tumor burden and inhibit metastasis
    • Lawson KA, Anderson K, Snyder RM, et al. Novel vitamin E analogue and 9-nitro-camptothecin administered as liposome aerosols decrease syngeneic mouse mammary tumor burden and inhibit metastasis. Cancer Chemother Pharmacol. 2004;54(5):421-431.
    • (2004) Cancer Chemother Pharmacol. , vol.54 , Issue.5 , pp. 421-431
    • Lawson, K.A.1    Anderson, K.2    Snyder, R.M.3
  • 58
    • 67349131897 scopus 로고    scopus 로고
    • Combination chemotherapeutic dry powder aerosols via controlled nanoparticle agglomeration
    • El-Gendy N, Berkland C. Combination chemotherapeutic dry powder aerosols via controlled nanoparticle agglomeration. Pharm Res. 2009; 26(7):1752-1763.
    • (2009) Pharm Res. , vol.26 , Issue.7 , pp. 1752-1763
    • El-Gendy, N.1    Berkland, C.2
  • 59
    • 33745904988 scopus 로고    scopus 로고
    • Formulation and cytotoxicity of doxorubicin nanoparticles carried by dry powder aerosol particles
    • Azarmi S, Tao X, Chen H, et al. Formulation and cytotoxicity of doxorubicin nanoparticles carried by dry powder aerosol particles. Int J Pharm. 2006;319(1-2):155-161.
    • (2006) Int J Pharm. , vol.319 , Issue.1-2 , pp. 155-161
    • Azarmi, S.1    Tao, X.2    Chen, H.3
  • 60
    • 33745026711 scopus 로고    scopus 로고
    • Pharmacokinetics of 5-fluorouracil in the hamster following inhalation delivery of lipidcoated nanoparticles
    • Hitzman CJ, Wattenberg LW, Wiedmann TS. Pharmacokinetics of 5-fluorouracil in the hamster following inhalation delivery of lipidcoated nanoparticles. J Pharm Sci. 2006;95(6):1196-1211.
    • (2006) J Pharm Sci. , vol.95 , Issue.6 , pp. 1196-1211
    • Hitzman, C.J.1    Wattenberg, L.W.2    Wiedmann, T.S.3
  • 61
    • 77955449671 scopus 로고    scopus 로고
    • Aerosol gemcitabine: Preclinical safety and in vivo antitumor activity in osteosarcoma-bearing dogs
    • Rodriguez CO Jr, Crabbs TA, Wilson DW, et al. Aerosol gemcitabine: preclinical safety and in vivo antitumor activity in osteosarcoma-bearing dogs. J Aerosol Med Pulm Drug Deliv. 2010;23(4):197-206.
    • (2010) J Aerosol Med Pulm Drug Deliv. , vol.23 , Issue.4 , pp. 197-206
    • Rodriguez Jr., C.O.1    Crabbs, T.A.2    Wilson, D.W.3
  • 62
    • 22244439824 scopus 로고    scopus 로고
    • Aerosol gemcitabine inhibits the growth of primary osteosarcoma and osteosarcoma lung metastases
    • Koshkina NV, Kleinerman ES. Aerosol gemcitabine inhibits the growth of primary osteosarcoma and osteosarcoma lung metastases. Int J Cancer. 2005;116(3):458-463.
    • (2005) Int J Cancer. , vol.116 , Issue.3 , pp. 458-463
    • Koshkina, N.V.1    Kleinerman, E.S.2
  • 63
    • 0032807781 scopus 로고    scopus 로고
    • Distribution of camptothecin after delivery as a liposome aerosol or following intramuscular injection in mice
    • Koshkina NV, Gilbert BE, Waldrep JC, Seryshev A, Knight V. Distribution of camptothecin after delivery as a liposome aerosol or following intramuscular injection in mice. Cancer Chemother Pharmacol. 1999;44(3):187-192.
    • (1999) Cancer Chemother Pharmacol. , vol.44 , Issue.3 , pp. 187-192
    • Koshkina, N.V.1    Gilbert, B.E.2    Waldrep, J.C.3    Seryshev, A.4    Knight, V.5
  • 65
    • 0019170979 scopus 로고
    • Aerosols and humidity therapy. Generation and respiratory deposition of therapeutic aerosols
    • Swift DL. Aerosols and humidity therapy. Generation and respiratory deposition of therapeutic aerosols. Am Rev Respir Dis. 1980; 122(5 Pt 2):71-77.
    • (1980) Am Rev Respir Dis. , vol.122 , Issue.5 PART 2 , pp. 71-77
    • Swift, D.L.1
  • 66
    • 0028146817 scopus 로고
    • Regional deposition of saline aerosols of different tonicities in normal and asthmatic subjects
    • Phipps PR, Gonda I, Anderson SD, Bailey D, Bautovich G. Regional deposition of saline aerosols of different tonicities in normal and asthmatic subjects. Eur Respir J. 1994;7(8):1474-1482.
    • (1994) Eur Respir J. , vol.7 , Issue.8 , pp. 1474-1482
    • Phipps, P.R.1    Gonda, I.2    Anderson, S.D.3    Bailey, D.4    Bautovich, G.5
  • 67
    • 0030880659 scopus 로고    scopus 로고
    • Distribution of lymphatic stomata on the pleural surface of the thoracic cavity and the surface topography of the pleural mesothelium in the golden hamster
    • Shinohara H. Distribution of lymphatic stomata on the pleural surface of the thoracic cavity and the surface topography of the pleural mesothelium in the golden hamster. Anat Rec. 1997;249(1):16-23.
    • (1997) Anat Rec. , vol.249 , Issue.1 , pp. 16-23
    • Shinohara, H.1
  • 68
    • 0027467708 scopus 로고
    • Mechanical factors in lung liquid distribution
    • Lai-Fook SJ. Mechanical factors in lung liquid distribution. Annu Rev Physiol. 1993;55:155-179.
    • (1993) Annu Rev Physiol. , vol.55 , pp. 155-179
    • Lai-Fook, S.J.1
  • 72
    • 0025754447 scopus 로고
    • Inhaled drugs and the lung
    • Summers QA. Inhaled drugs and the lung. Clin Exp Allergy. 1991;21(3): 259-268.
    • (1991) Clin Exp Allergy. , vol.21 , Issue.3 , pp. 259-268
    • Summers, Q.A.1
  • 75
    • 0027443196 scopus 로고
    • Mathematical model for the selective deposition of inhaled pharmaceuticals
    • Martonen TB. Mathematical model for the selective deposition of inhaled pharmaceuticals. J Pharm Sci. 1993;82(12):1191-1199.
    • (1993) J Pharm Sci. , vol.82 , Issue.12 , pp. 1191-1199
    • Martonen, T.B.1
  • 76
    • 0033931658 scopus 로고    scopus 로고
    • Drug properties affecting aerosol behavior
    • Suarez S, Hickey AJ. Drug properties affecting aerosol behavior. Respir Care. 2000;45(6):652-666.
    • (2000) Respir Care. , vol.45 , Issue.6 , pp. 652-666
    • Suarez, S.1    Hickey, A.J.2
  • 77
    • 0023612242 scopus 로고
    • Quantitative deposition of aerosolized gentamicin in cystic fibrosis
    • Ilowite JS, Gorvoy JD, Smaldone GC. Quantitative deposition of aerosolized gentamicin in cystic fibrosis. Am Rev Respir Dis. 1987;136(6): 1445-1449.
    • (1987) Am Rev Respir Dis. , vol.136 , Issue.6 , pp. 1445-1449
    • Ilowite, J.S.1    Gorvoy, J.D.2    Smaldone, G.C.3
  • 78
    • 0021929958 scopus 로고
    • Evaluation of quantitative aerosol techniques for use in bronchoprovocation studies
    • Messina MS, Smaldone GC. Evaluation of quantitative aerosol techniques for use in bronchoprovocation studies. J Allergy Clin Immunol. 1985;75(2):252-257.
    • (1985) J Allergy Clin Immunol. , vol.75 , Issue.2 , pp. 252-257
    • Messina, M.S.1    Smaldone, G.C.2
  • 79
    • 0017362241 scopus 로고
    • Pulmonary aerosol deposition in chronic bronchitis: Intermittent positive pressure breathing versus quiet breathing
    • Dolovich MB, Killian D, Wolff RK, Obminski G, Newhouse MT. Pulmonary aerosol deposition in chronic bronchitis: intermittent positive pressure breathing versus quiet breathing. Am Rev Respir Dis. 1977; 115(3):397-402.
    • (1977) Am Rev Respir Dis. , vol.115 , Issue.3 , pp. 397-402
    • Dolovich, M.B.1    Killian, D.2    Wolff, R.K.3    Obminski, G.4    Newhouse, M.T.5
  • 80
    • 0017234033 scopus 로고
    • Aerosol penetrance: A sensitive index of peripheral airways obstruction
    • Dolovich MB, Sanchis J, Rossman C, Newhouse MT. Aerosol penetrance: a sensitive index of peripheral airways obstruction. J Appl Physiol. 1976;40(3):468-471.
    • (1976) J Appl Physiol. , vol.40 , Issue.3 , pp. 468-471
    • Dolovich, M.B.1    Sanchis, J.2    Rossman, C.3    Newhouse, M.T.4
  • 81
    • 0016694576 scopus 로고
    • Interrelationships of the volume and time components of individual breaths in resting man
    • Davis JN, Stagg D. Interrelationships of the volume and time components of individual breaths in resting man. J Physiol. 1975;245(2): 481-498.
    • (1975) J Physiol. , vol.245 , Issue.2 , pp. 481-498
    • Davis, J.N.1    Stagg, D.2
  • 82
    • 0035035106 scopus 로고    scopus 로고
    • Improved respiratory delivery of the anticancer drugs, camptothecin and paclitaxel, with 5% CO2-enriched air: Pharmacokinetic studies
    • Koshkina NV, Knight V, Gilbert BE, Golunski E, Roberts L, Waldrep JC. Improved respiratory delivery of the anticancer drugs, camptothecin and paclitaxel, with 5% CO2-enriched air: pharmacokinetic studies. Cancer Chemother Pharmacol. 2001;47(5):451-456.
    • (2001) Cancer Chemother Pharmacol. , vol.47 , Issue.5 , pp. 451-456
    • Koshkina, N.V.1    Knight, V.2    Gilbert, B.E.3    Golunski, E.4    Roberts, L.5    Waldrep, J.C.6
  • 83
    • 0032171016 scopus 로고    scopus 로고
    • Negative affect, respiratory reactivity, and somatic complaints in a CO2 enriched air inhalation paradigm
    • Stegen K, Neujens A, Crombez G, Hermans D, Van de Woestijne KP, Van den Bergh O. Negative affect, respiratory reactivity, and somatic complaints in a CO2 enriched air inhalation paradigm. Biol Psychol. 1998;49(1-2):109-122.
    • (1998) Biol Psychol. , vol.49 , Issue.1-2 , pp. 109-122
    • Stegen, K.1    Neujens, A.2    Crombez, G.3    Hermans, D.4    Van de Woestijne, K.P.5    Van den Bergh, O.6
  • 84
    • 54049158421 scopus 로고    scopus 로고
    • Modeling airflow and particle transport/ deposition in pulmonary airways
    • Kleinstreuer C, Zhang Z, Li Z. Modeling airflow and particle transport/ deposition in pulmonary airways. Respir Physiol Neurobiol. 2008;163(1-3):128-138.
    • (2008) Respir Physiol Neurobiol. , vol.163 , Issue.1-3 , pp. 128-138
    • Kleinstreuer, C.1    Zhang, Z.2    Li, Z.3
  • 85
    • 56449109262 scopus 로고    scopus 로고
    • Airflow and nanoparticle deposition in a 16-generation tracheobronchial airway model
    • Zhang Z, Kleinstreuer C, Kim CS. Airflow and nanoparticle deposition in a 16-generation tracheobronchial airway model. Ann Biomed Eng. 2008;36(12):2095-2110.
    • (2008) Ann Biomed Eng. , vol.36 , Issue.12 , pp. 2095-2110
    • Zhang, Z.1    Kleinstreuer, C.2    Kim, C.S.3
  • 87
    • 0034662608 scopus 로고    scopus 로고
    • Absence of functional lymphatics within a murine sarcoma: A molecular and functional evaluation
    • Leu AJ, Berk DA, Lymboussaki A, Alitalo K, Jain RK. Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation. Cancer Res. 2000;60(16):4324-4327.
    • (2000) Cancer Res. , vol.60 , Issue.16 , pp. 4324-4327
    • Leu, A.J.1    Berk, D.A.2    Lymboussaki, A.3    Alitalo, K.4    Jain, R.K.5
  • 88
    • 0036548794 scopus 로고    scopus 로고
    • Dissecting tumour pathophysiology using intravital microscopy
    • Jain RK, Munn LL, Fukumura D. Dissecting tumour pathophysiology using intravital microscopy. Nat Rev Cancer. 2002;2(4):266-276.
    • (2002) Nat Rev Cancer. , vol.2 , Issue.4 , pp. 266-276
    • Jain, R.K.1    Munn, L.L.2    Fukumura, D.3
  • 89
    • 0031558243 scopus 로고    scopus 로고
    • Delivery of molecular and cellular medicine to solid tumors
    • Jain RK. Delivery of molecular and cellular medicine to solid tumors. Adv Drug Deliv Rev. 1997;26(2-3):71-90.
    • (1997) Adv Drug Deliv Rev. , vol.26 , Issue.2-3 , pp. 71-90
    • Jain, R.K.1
  • 90
    • 0032526004 scopus 로고    scopus 로고
    • Interstitial fluid pressure in cervical carcinoma: Within tumor heterogeneity, and relation to oxygen tension
    • Milosevic MF, Fyles AW, Wong R, et al. Interstitial fluid pressure in cervical carcinoma: within tumor heterogeneity, and relation to oxygen tension. Cancer. 1998;82(12):2418-2426.
    • (1998) Cancer. , vol.82 , Issue.12 , pp. 2418-2426
    • Milosevic, M.F.1    Fyles, A.W.2    Wong, R.3
  • 91
    • 4944266313 scopus 로고    scopus 로고
    • High interstitial fluid pressure-an obstacle in cancer therapy
    • Heldin CH, Rubin K, Pietras K, Ostman A. High interstitial fluid pressure-an obstacle in cancer therapy. Nat Rev Cancer. 2004;4(10): 806-813.
    • (2004) Nat Rev Cancer. , vol.4 , Issue.10 , pp. 806-813
    • Heldin, C.H.1    Rubin, K.2    Pietras, K.3    Ostman, A.4
  • 92
    • 0028470454 scopus 로고
    • Barriers to drug delivery in solid tumors
    • Jain RK. Barriers to drug delivery in solid tumors. Sci Am. 1994;271(1): 58-65.
    • (1994) Sci Am. , vol.271 , Issue.1 , pp. 58-65
    • Jain, R.K.1
  • 93
    • 0023219734 scopus 로고
    • Transport of molecules in the tumor interstitium: A review
    • Jain RK. Transport of molecules in the tumor interstitium: a review. Cancer Res. 1987;47(12):3039-3051.
    • (1987) Cancer Res. , vol.47 , Issue.12 , pp. 3039-3051
    • Jain, R.K.1
  • 95
    • 0021337761 scopus 로고
    • Alteration in osmolarity of inhaled aerosols cause bronchoconstriction and cough, but absence of a permeant anion causes cough alone
    • Eschenbacher WL, Boushey HA, Sheppard D. Alteration in osmolarity of inhaled aerosols cause bronchoconstriction and cough, but absence of a permeant anion causes cough alone. Am Rev Respir Dis. 1984; 129(2):211-215.
    • (1984) Am Rev Respir Dis. , vol.129 , Issue.2 , pp. 211-215
    • Eschenbacher, W.L.1    Boushey, H.A.2    Sheppard, D.3
  • 97
    • 0025358352 scopus 로고
    • Replacing CFC aerosols with powders
    • Dolovich MB, Ramsdale EH. Replacing CFC aerosols with powders. CMAJ. 1990;142(10):1036.
    • (1990) CMAJ. , vol.142 , Issue.10 , pp. 1036
    • Dolovich, M.B.1    Ramsdale, E.H.2
  • 98
    • 0021685262 scopus 로고
    • Therapeutic inhalation agents and devices. Effectiveness in asthma and bronchitis
    • Newman SP. Therapeutic inhalation agents and devices. Effectiveness in asthma and bronchitis. Postgrad Med. 1984;76(5):194-203.
    • (1984) Postgrad Med. , vol.76 , Issue.5 , pp. 194-203
    • Newman, S.P.1
  • 99
    • 0023186167 scopus 로고
    • Human variation in the peripheral airspace deposition of inhaled particles
    • Bennett WD, Smaldone GC. Human variation in the peripheral airspace deposition of inhaled particles. J Appl Physiol. 1987;62(4): 1603-1610.
    • (1987) J Appl Physiol. , vol.62 , Issue.4 , pp. 1603-1610
    • Bennett, W.D.1    Smaldone, G.C.2
  • 100
    • 0019780882 scopus 로고
    • Aerosol penetration into the lung; influence on airway responses
    • Dolovich M, Ryan G, Newhouse MT. Aerosol penetration into the lung; influence on airway responses. Chest. 1981;80(Suppl 6):834-836.
    • (1981) Chest. , vol.80 , Issue.SUPPL. 6 , pp. 834-836
    • Dolovich, M.1    Ryan, G.2    Newhouse, M.T.3
  • 101
    • 0020322578 scopus 로고
    • Problems patients have using pressurized aerosol inhalers
    • Crompton GK. Problems patients have using pressurized aerosol inhalers. Eur J Respir Dis Suppl. 1982;119:101-104.
    • (1982) Eur J Respir Dis Suppl. , vol.119 , pp. 101-104
    • Crompton, G.K.1
  • 102
    • 0019377972 scopus 로고
    • Deposition of pressurised aerosols in the human respiratory tract
    • Newman SP, Pavia D, Moren F, Sheahan NF, Clarke SW. Deposition of pressurised aerosols in the human respiratory tract. Thorax. 1981; 36(1):52-55.
    • (1981) Thorax. , vol.36 , Issue.1 , pp. 52-55
    • Newman, S.P.1    Pavia, D.2    Moren, F.3    Sheahan, N.F.4    Clarke, S.W.5
  • 103
    • 0020317462 scopus 로고
    • Effects of various inhalation modes on the deposition of radioactive pressurized aerosols
    • Newman SP, Pavia D, Garland N, Clarke SW. Effects of various inhalation modes on the deposition of radioactive pressurized aerosols. Eur J Respir Dis Suppl. 1982;119:57-65.
    • (1982) Eur J Respir Dis Suppl. , vol.119 , pp. 57-65
    • Newman, S.P.1    Pavia, D.2    Garland, N.3    Clarke, S.W.4
  • 104
    • 0017620023 scopus 로고
    • Effect of lung function and mode of inhalation on penetration of aerosol into the human lung
    • Pavia D, Thomson ML, Clarke SW, Shannon HS. Effect of lung function and mode of inhalation on penetration of aerosol into the human lung. Thorax. 1977;32(2):194-197.
    • (1977) Thorax. , vol.32 , Issue.2 , pp. 194-197
    • Pavia, D.1    Thomson, M.L.2    Clarke, S.W.3    Shannon, H.S.4
  • 105
    • 0025951893 scopus 로고
    • Improvement of drug delivery with a breath actuated pressurised aerosol for patients with poor inhaler technique
    • Newman SP, Weisz AW, Talaee N, Clarke SW. Improvement of drug delivery with a breath actuated pressurised aerosol for patients with poor inhaler technique. Thorax. 1991;46(10):712-716.
    • (1991) Thorax. , vol.46 , Issue.10 , pp. 712-716
    • Newman, S.P.1    Weisz, A.W.2    Talaee, N.3    Clarke, S.W.4
  • 106
    • 0027376998 scopus 로고
    • A comparison of breath-actuated and conventional metered-dose inhaler inhalation techniques in elderly subjects
    • Chapman KR, Love L, Brubaker H. A comparison of breath-actuated and conventional metered-dose inhaler inhalation techniques in elderly subjects. Chest. 1993;104(5):1332-1337.
    • (1993) Chest. , vol.104 , Issue.5 , pp. 1332-1337
    • Chapman, K.R.1    Love, L.2    Brubaker, H.3
  • 107
    • 0031427639 scopus 로고    scopus 로고
    • Rationale for spacer use in children
    • Dolovich M. Rationale for spacer use in children. Pediatr Pulmonol Suppl. 1997;16:184-185.
    • (1997) Pediatr Pulmonol Suppl. , vol.16 , pp. 184-185
    • Dolovich, M.1
  • 108
    • 0030000457 scopus 로고    scopus 로고
    • Inhalers and nebulizers: Which to choose and why
    • Pedersen S. Inhalers and nebulizers: which to choose and why. Respir Med. 1996;90(2):69-77.
    • (1996) Respir Med. , vol.90 , Issue.2 , pp. 69-77
    • Pedersen, S.1
  • 109
    • 0032869779 scopus 로고    scopus 로고
    • New propellant-free technologies under investigation
    • Dolovich M. New propellant-free technologies under investigation. J Aerosol Med. 1999;12 Suppl 1:S9-S17.
    • (1999) J Aerosol Med. , vol.12 , Issue.SUPPL. 1
    • Dolovich, M.1
  • 110
    • 0024584103 scopus 로고
    • Deposition and clinical efficacy of terbutaline sulphate from Turbuhaler, a new multi-dose powder inhaler
    • Newman SP, Moren F, Trofast E, Talaee N, Clarke SW. Deposition and clinical efficacy of terbutaline sulphate from Turbuhaler, a new multi-dose powder inhaler. Eur Respir J. 1989;2(3): 247-252.
    • (1989) Eur Respir J. , vol.2 , Issue.3 , pp. 247-252
    • Newman, S.P.1    Moren, F.2    Trofast, E.3    Talaee, N.4    Clarke, S.W.5
  • 111
    • 0344943933 scopus 로고    scopus 로고
    • Pulmonary drug delivery. Part II: The role of inhalant delivery devices and drug formulations in therapeutic effectiveness of aerosolized medications
    • Labiris NR, Dolovich MB. Pulmonary drug delivery. Part II: the role of inhalant delivery devices and drug formulations in therapeutic effectiveness of aerosolized medications. Br J Clin Pharmacol. 2003; 56(6):600-612.
    • (2003) Br J Clin Pharmacol. , vol.56 , Issue.6 , pp. 600-612
    • Labiris, N.R.1    Dolovich, M.B.2
  • 112
    • 0028354478 scopus 로고
    • Lung deposition of budesonide inhaled via Turbuhaler: A comparison with terbutaline sulphate in normal subjects
    • Borgstrom L, Bondesson E, Moren F, Trofast E, Newman SP. Lung deposition of budesonide inhaled via Turbuhaler: a comparison with terbutaline sulphate in normal subjects. Eur Respir J. 1994;7(1):69-73.
    • (1994) Eur Respir J. , vol.7 , Issue.1 , pp. 69-73
    • Borgstrom, L.1    Bondesson, E.2    Moren, F.3    Trofast, E.4    Newman, S.P.5
  • 113
    • 0027228520 scopus 로고
    • The relationship between powder inhaler resistance and peak inspiratory conditions in healthy volunteers-implications for in vitro testing
    • Clark AR, Hollingworth AM. The relationship between powder inhaler resistance and peak inspiratory conditions in healthy volunteers-implications for in vitro testing. J Aerosol Med. Summer 1993;6(2): 99-110.
    • (1993) J Aerosol Med. Summer , vol.6 , Issue.2 , pp. 99-110
    • Clark, A.R.1    Hollingworth, A.M.2
  • 114
    • 0037292274 scopus 로고    scopus 로고
    • Is inhalation rate important for a dry powder inhaler? Using the In-Check Dial to identify these rates
    • Chrystyn H. Is inhalation rate important for a dry powder inhaler? Using the In-Check Dial to identify these rates. Respir Med. 2003; 97(2):181-187.
    • (2003) Respir Med. , vol.97 , Issue.2 , pp. 181-187
    • Chrystyn, H.1
  • 115
    • 40049096205 scopus 로고    scopus 로고
    • Effect of incorrect use of dry powder inhalers on management of patients with asthma and COPD
    • Lavorini F, Magnan A, Dubus JC, et al. Effect of incorrect use of dry powder inhalers on management of patients with asthma and COPD. Respir Med. 2008;102(4):593-604.
    • (2008) Respir Med. , vol.102 , Issue.4 , pp. 593-604
    • Lavorini, F.1    Magnan, A.2    Dubus, J.C.3
  • 116
    • 48849091581 scopus 로고    scopus 로고
    • Determination of factors controlling the particle size in nanoemulsions using artificial neural networks
    • Amani A, York P, Chrystyn H, Clark BJ, Do DQ. Determination of factors controlling the particle size in nanoemulsions using artificial neural networks. Eur J Pharm Sci. 2008;35(1-2):42-51.
    • (2008) Eur J Pharm Sci. , vol.35 , Issue.1-2 , pp. 42-51
    • Amani, A.1    York, P.2    Chrystyn, H.3    Clark, B.J.4    Do, D.Q.5
  • 117
    • 13544253826 scopus 로고    scopus 로고
    • Device selection and outcomes of aerosol therapy: Evidence-based guidelines: American College of Chest Physicians/American College of Asthma, Allergy, and Immunology
    • Dolovich MB, Ahrens RC, Hess DR, et al. Device selection and outcomes of aerosol therapy: Evidence-based guidelines: American College of Chest Physicians/American College of Asthma, Allergy, and Immunology. Chest. 2005;127(1):335-371.
    • (2005) Chest. , vol.127 , Issue.1 , pp. 335-371
    • Dolovich, M.B.1    Ahrens, R.C.2    Hess, D.R.3
  • 118
    • 0030988266 scopus 로고    scopus 로고
    • Selecting and using nebuliser equipment
    • Kendrick AH, Smith EC, Wilson RS. Selecting and using nebuliser equipment. Thorax. 1997;52 Suppl 2:S92-S101.
    • (1997) Thorax. , vol.52 , Issue.SUPPL. 2
    • Kendrick, A.H.1    Smith, E.C.2    Wilson, R.S.3
  • 119
    • 0034895786 scopus 로고    scopus 로고
    • European Respiratory Society Guidelines on the use of nebulizers
    • Boe J, Dennis JH, O'Driscoll BR, et al. European Respiratory Society Guidelines on the use of nebulizers. Eur Respir J. 2001;18(1):228-242.
    • (2001) Eur Respir J. , vol.18 , Issue.1 , pp. 228-242
    • Boe, J.1    Dennis, J.H.2    O'Driscoll, B.R.3
  • 120
    • 0029152028 scopus 로고
    • Comparison of twenty three nebulizer/compressor combinations for domiciliary use
    • Smith EC, Denyer J, Kendrick AH. Comparison of twenty three nebulizer/compressor combinations for domiciliary use. Eur Respir J. 1995;8(7):1214-1221.
    • (1995) Eur Respir J. , vol.8 , Issue.7 , pp. 1214-1221
    • Smith, E.C.1    Denyer, J.2    Kendrick, A.H.3
  • 121
    • 0042026773 scopus 로고    scopus 로고
    • Peripheral deposition of alpha1-protease inhibitor using commercial inhalation devices
    • Brand P, Beckmann H, Maas Enriquez M, et al. Peripheral deposition of alpha1-protease inhibitor using commercial inhalation devices. Eur Respir J. 2003;22(2):263-267.
    • (2003) Eur Respir J. , vol.22 , Issue.2 , pp. 263-267
    • Brand, P.1    Beckmann, H.2    Maas Enriquez, M.3
  • 122
  • 123
    • 33744986730 scopus 로고    scopus 로고
    • Nebulization of liposomal rh-Cu/Zn-SOD with a novel vibrating membrane nebulizer
    • Wagner A, Vorauer-Uhl K, Katinger H. Nebulization of liposomal rh-Cu/Zn-SOD with a novel vibrating membrane nebulizer. J Liposome Res. 2006;16(2):113-125.
    • (2006) J Liposome Res. , vol.16 , Issue.2 , pp. 113-125
    • Wagner, A.1    Vorauer-Uhl, K.2    Katinger, H.3
  • 124
    • 33745636578 scopus 로고    scopus 로고
    • Formulations generated from ethanol-based proliposomes for delivery via medical nebulizers
    • Elhissi AM, Karnam KK, Danesh-Azari MR, Gill HS, Taylor KM. Formulations generated from ethanol-based proliposomes for delivery via medical nebulizers. J Pharm Pharmacol. 2006;58(7):887-894.
    • (2006) J Pharm Pharmacol. , vol.58 , Issue.7 , pp. 887-894
    • Elhissi, A.M.1    Karnam, K.K.2    Danesh-Azari, M.R.3    Gill, H.S.4    Taylor, K.M.5
  • 125
    • 33846071525 scopus 로고    scopus 로고
    • Iloprost-containing liposomes for aerosol application in pulmonary arterial hypertension: Formulation aspects and stability
    • Kleemann E, Schmehl T, Gessler T, Bakowsky U, Kissel T, Seeger W. Iloprost-containing liposomes for aerosol application in pulmonary arterial hypertension: formulation aspects and stability. Pharm Res. 2007;24(2):277-287.
    • (2007) Pharm Res. , vol.24 , Issue.2 , pp. 277-287
    • Kleemann, E.1    Schmehl, T.2    Gessler, T.3    Bakowsky, U.4    Kissel, T.5    Seeger, W.6
  • 126
    • 61449495105 scopus 로고    scopus 로고
    • Aerosol delivery of recombinant human DNase I: In vitro comparison of a vibrating-mesh nebulizer with a jet nebulizer
    • Johnson JC, Waldrep JC, Guo J, Dhand R. Aerosol delivery of recombinant human DNase I: in vitro comparison of a vibrating-mesh nebulizer with a jet nebulizer. Respir Care. 2008;53(12):1703-1708.
    • (2008) Respir Care. , vol.53 , Issue.12 , pp. 1703-1708
    • Johnson, J.C.1    Waldrep, J.C.2    Guo, J.3    Dhand, R.4
  • 127
    • 25844469046 scopus 로고    scopus 로고
    • Variation in pediatric aerosol delivery: Importance of facemask
    • Smaldone GC, Berg E, Nikander K. Variation in pediatric aerosol delivery: importance of facemask. J Aerosol Med. 2005;18(3):354-363.
    • (2005) J Aerosol Med. , vol.18 , Issue.3 , pp. 354-363
    • Smaldone, G.C.1    Berg, E.2    Nikander, K.3
  • 128
    • 39449093951 scopus 로고    scopus 로고
    • Facial and ocular deposition of nebulized budesonide: Effects of face mask design
    • Harris KW, Smaldone GC. Facial and ocular deposition of nebulized budesonide: effects of face mask design. Chest. 2008;133(2):482-488.
    • (2008) Chest. , vol.133 , Issue.2 , pp. 482-488
    • Harris, K.W.1    Smaldone, G.C.2
  • 129
    • 34247584997 scopus 로고    scopus 로고
    • Facemask design, facial deposition, and delivered dose of nebulized aerosols
    • Smaldone GC, Sangwan S, Shah A. Facemask design, facial deposition, and delivered dose of nebulized aerosols. J Aerosol Med. 2007;20 Suppl 1:S66-S75.
    • (2007) J Aerosol Med. , vol.20 , Issue.SUPPL. 1
    • Smaldone, G.C.1    Sangwan, S.2    Shah, A.3
  • 131
    • 50249123944 scopus 로고    scopus 로고
    • Targeted drug-aerosol delivery in the human respiratory system
    • Kleinstreuer C, Zhang Z, Donohue JF. Targeted drug-aerosol delivery in the human respiratory system. Annu Rev Biomed Eng. 2008;10: 195-220.
    • (2008) Annu Rev Biomed Eng. , vol.10 , pp. 195-220
    • Kleinstreuer, C.1    Zhang, Z.2    Donohue, J.F.3
  • 132
    • 0033618483 scopus 로고    scopus 로고
    • A new approach to modelling the relationship between in vitro and in vivo drug dissolution/absorption
    • Dunne A, O'Hara T, Devane J. A new approach to modelling the relationship between in vitro and in vivo drug dissolution/absorption. Stat Med. 1999;18(14):1865-1876.
    • (1999) Stat Med. , vol.18 , Issue.14 , pp. 1865-1876
    • Dunne, A.1    O'Hara, T.2    Devane, J.3
  • 133
    • 0032879891 scopus 로고    scopus 로고
    • Optimizing the in vitro performance of Respimat
    • Zierenberg B. Optimizing the in vitro performance of Respimat. J Aerosol Med. 1999;12 Suppl 1:S19-S24.
    • (1999) J Aerosol Med. , vol.12 , Issue.SUPPL. 1
    • Zierenberg, B.1
  • 134
    • 0029757981 scopus 로고    scopus 로고
    • Efficient delivery to the lungs of flunisolide aerosol from a new portable handheld multidose nebulizer
    • Newman SP, Steed KP, Reader SJ, Hooper G, Zierenberg B. Efficient delivery to the lungs of flunisolide aerosol from a new portable handheld multidose nebulizer. J Pharm Sci. 1996;85(9):960-964.
    • (1996) J Pharm Sci. , vol.85 , Issue.9 , pp. 960-964
    • Newman, S.P.1    Steed, K.P.2    Reader, S.J.3    Hooper, G.4    Zierenberg, B.5
  • 135
    • 0031977041 scopus 로고    scopus 로고
    • Lung deposition of fenoterol and flunisolide delivered using a novel device for inhaled medicines: Comparison of RESPIMAT with conventional metered-dose inhalers with and without spacer devices
    • Newman SP, Brown J, Steed KP, Reader SJ, Kladders H. Lung deposition of fenoterol and flunisolide delivered using a novel device for inhaled medicines: comparison of RESPIMAT with conventional metered-dose inhalers with and without spacer devices. Chest. 1998; 113(4):957-963.
    • (1998) Chest. , vol.113 , Issue.4 , pp. 957-963
    • Newman, S.P.1    Brown, J.2    Steed, K.P.3    Reader, S.J.4    Kladders, H.5
  • 136
    • 77956338422 scopus 로고    scopus 로고
    • A one-year trial of tiotropium Respimat plus usual therapy in COPD patients
    • Bateman ED, Tashkin D, Siafakas N, et al. A one-year trial of tiotropium Respimat plus usual therapy in COPD patients. Respir Med. 2010;104(10):1460-1472.
    • (2010) Respir Med. , vol.104 , Issue.10 , pp. 1460-1472
    • Bateman, E.D.1    Tashkin, D.2    Siafakas, N.3
  • 137
    • 0030964439 scopus 로고    scopus 로고
    • Colloidal systems for tumor targeting
    • Storm G, Crommelin DJ. Colloidal systems for tumor targeting. Hybridoma. 1997;16(1):119-125.
    • (1997) Hybridoma. , vol.16 , Issue.1 , pp. 119-125
    • Storm, G.1    Crommelin, D.J.2
  • 138
    • 0031922895 scopus 로고    scopus 로고
    • Effect of dose and release rate on pulmonary targeting of liposomal triamcinolone acetonide phosphate
    • Suarez S, Gonzalez-Rothi RJ, Schreier H, Hochhaus G. Effect of dose and release rate on pulmonary targeting of liposomal triamcinolone acetonide phosphate. Pharm Res. 1998;15(3):461-465.
    • (1998) Pharm Res. , vol.15 , Issue.3 , pp. 461-465
    • Suarez, S.1    Gonzalez-Rothi, R.J.2    Schreier, H.3    Hochhaus, G.4
  • 139
    • 0026526983 scopus 로고
    • Factors affecting the release rate of terbutaline from liposome formulations after intratracheal instillation in the guinea pig
    • Fielding RM, Abra RM. Factors affecting the release rate of terbutaline from liposome formulations after intratracheal instillation in the guinea pig. Pharm Res. 1992;9(2):220-223.
    • (1992) Pharm Res. , vol.9 , Issue.2 , pp. 220-223
    • Fielding, R.M.1    Abra, R.M.2
  • 140
    • 21744457648 scopus 로고    scopus 로고
    • Carrier-based strategies for targeting protein and peptide drugs to the lungs
    • Cryan SA. Carrier-based strategies for targeting protein and peptide drugs to the lungs. AAPS J. 2005;7(1):E20-E41.
    • (2005) AAPS J. , vol.7 , Issue.1
    • Cryan, S.A.1
  • 141
    • 0030482298 scopus 로고    scopus 로고
    • Pulmonary targeting of liposomal triamcinolone acetonide phosphate
    • Gonzalez-Rothi RJ, Suarez S, Hochhaus G, et al. Pulmonary targeting of liposomal triamcinolone acetonide phosphate. Pharm Res. 1996; 13(11):1699-1703.
    • (1996) Pharm Res. , vol.13 , Issue.11 , pp. 1699-1703
    • Gonzalez-Rothi, R.J.1    Suarez, S.2    Hochhaus, G.3
  • 142
    • 0025851012 scopus 로고
    • Liposomes and pulmonary alveolar macrophages: Functional and morphologic interactions
    • Gonzalez-Rothi RJ, Straub L, Cacace JL, Schreier H. Liposomes and pulmonary alveolar macrophages: functional and morphologic interactions. Exp Lung Res. 1991;17(4):687-705.
    • (1991) Exp Lung Res. , vol.17 , Issue.4 , pp. 687-705
    • Gonzalez-Rothi, R.J.1    Straub, L.2    Cacace, J.L.3    Schreier, H.4
  • 144
    • 0031729149 scopus 로고    scopus 로고
    • Liposomal drug formulations. Rationale for development and what we can expect for the future
    • Allen TM. Liposomal drug formulations. Rationale for development and what we can expect for the future. Drugs. 1998;56(5):747-756.
    • (1998) Drugs. , vol.56 , Issue.5 , pp. 747-756
    • Allen, T.M.1
  • 145
    • 0030669761 scopus 로고    scopus 로고
    • Physicochemical properties and in vitro toxicity of cationic liposome cDNA complexes
    • Schreier H, Gagne L, Bock T, et al. Physicochemical properties and in vitro toxicity of cationic liposome cDNA complexes. Pharm Acta Helv. 1997;72(4):215-223.
    • (1997) Pharm Acta Helv. , vol.72 , Issue.4 , pp. 215-223
    • Schreier, H.1    Gagne, L.2    Bock, T.3
  • 146
    • 0025245057 scopus 로고
    • Nebulization of liposomes. I. Effects of lipid composition
    • Niven RW, Schreier H. Nebulization of liposomes. I. Effects of lipid composition. Pharm Res. 1990;7(11):1127-1133.
    • (1990) Pharm Res. , vol.7 , Issue.11 , pp. 1127-1133
    • Niven, R.W.1    Schreier, H.2
  • 147
    • 0037038303 scopus 로고    scopus 로고
    • A facile method of delivery of liposomes by nebulization
    • Desai TR, Hancock RE, Finlay WH. A facile method of delivery of liposomes by nebulization. J Control Release. 2002;84(1-2):69-78.
    • (2002) J Control Release. , vol.84 , Issue.1-2 , pp. 69-78
    • Desai, T.R.1    Hancock, R.E.2    Finlay, W.H.3
  • 148
    • 0025911331 scopus 로고
    • Nebulization of liposomes. II. The effects of size and modeling of solute release profiles
    • Niven RW, Speer M, Schreier H. Nebulization of liposomes. II. The effects of size and modeling of solute release profiles. Pharm Res. 1991;8(2):217-221.
    • (1991) Pharm Res. , vol.8 , Issue.2 , pp. 217-221
    • Niven, R.W.1    Speer, M.2    Schreier, H.3
  • 149
    • 0026513264 scopus 로고
    • Nebulization of liposomes. III. The effects of operating conditions and local environment
    • Niven RW, Carvajal TM, Schreier H. Nebulization of liposomes. III. The effects of operating conditions and local environment. Pharm Res. 1992;9(4):515-520.
    • (1992) Pharm Res. , vol.9 , Issue.4 , pp. 515-520
    • Niven, R.W.1    Carvajal, T.M.2    Schreier, H.3
  • 150
    • 0035979417 scopus 로고    scopus 로고
    • Dry powder inhalation of liposomal ketotifen fumarate: Formulation and characterization
    • Joshi M, Misra A. Dry powder inhalation of liposomal ketotifen fumarate: formulation and characterization. Int J Pharm. 2001;223(1-2): 15-27.
    • (2001) Int J Pharm. , vol.223 , Issue.1-2 , pp. 15-27
    • Joshi, M.1    Misra, A.2
  • 151
    • 0034521195 scopus 로고    scopus 로고
    • Liposomes containing drug and cyclodextrin prepared by the one-step spray-drying method
    • Skalko-Basnet N, Pavelic Z, Becirevic-Lacan M. Liposomes containing drug and cyclodextrin prepared by the one-step spray-drying method. Drug Dev Ind Pharm. 2000;26(12):1279-1284.
    • (2000) Drug Dev Ind Pharm. , vol.26 , Issue.12 , pp. 1279-1284
    • Skalko-Basnet, N.1    Pavelic, Z.2    Becirevic-Lacan, M.3
  • 152
    • 0028335186 scopus 로고
    • Pulmonary retention of free and liposome-encapsulated tobramycin after intratracheal administration in uninfected rats and rats infected with Pseudomonas aeruginosa
    • Omri A, Beaulac C, Bouhajib M, Montplaisir S, Sharkawi M, Lagace J. Pulmonary retention of free and liposome-encapsulated tobramycin after intratracheal administration in uninfected rats and rats infected with Pseudomonas aeruginosa. Antimicrob Agents Chemother. 1994; 38(5):1090-1095.
    • (1994) Antimicrob Agents Chemother. , vol.38 , Issue.5 , pp. 1090-1095
    • Omri, A.1    Beaulac, C.2    Bouhajib, M.3    Montplaisir, S.4    Sharkawi, M.5    Lagace, J.6
  • 153
    • 0026586589 scopus 로고
    • Sterically stabilized liposomes. Reduction in electrophoretic mobility but not electrostatic surface potential
    • Woodle MC, Collins LR, Sponsler E, Kossovsky N, Papahadjopoulos D, Martin FJ. Sterically stabilized liposomes. Reduction in electrophoretic mobility but not electrostatic surface potential. Biophys J. 1992;61(4): 902-910.
    • (1992) Biophys J. , vol.61 , Issue.4 , pp. 902-910
    • Woodle, M.C.1    Collins, L.R.2    Sponsler, E.3    Kossovsky, N.4    Papahadjopoulos, D.5    Martin, F.J.6
  • 154
    • 0030890637 scopus 로고    scopus 로고
    • Lung specific stealth liposomes: Stability, biodistribution and toxicity of liposomal antitubercular drugs in mice
    • Deol P, Khuller GK. Lung specific stealth liposomes: stability, biodistribution and toxicity of liposomal antitubercular drugs in mice. Biochim Biophys Acta. 1997;1334(2-3):161-172.
    • (1997) Biochim Biophys Acta. , vol.1334 , Issue.2-3 , pp. 161-172
    • Deol, P.1    Khuller, G.K.2
  • 155
    • 0024488577 scopus 로고
    • Biodegradable polymers for controlled release of peptides and proteins
    • Hutchinson FG, Furr BJ. Biodegradable polymers for controlled release of peptides and proteins. Horiz Biochem Biophys. 1989;9:111-129.
    • (1989) Horiz Biochem Biophys. , vol.9 , pp. 111-129
    • Hutchinson, F.G.1    Furr, B.J.2
  • 156
    • 0036321111 scopus 로고    scopus 로고
    • Drug absorption by the respiratory mucosa: Cell culture models and particulate drug carriers
    • Ehrhardt C, Fiegel J, Fuchs S, et al. Drug absorption by the respiratory mucosa: cell culture models and particulate drug carriers. J Aerosol Med. 2002;15(2):131-139.
    • (2002) J Aerosol Med. , vol.15 , Issue.2 , pp. 131-139
    • Ehrhardt, C.1    Fiegel, J.2    Fuchs, S.3
  • 157
    • 0032863681 scopus 로고    scopus 로고
    • Pulmonary delivery of insulin with nebulized DL-lactide/glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect
    • Kawashima Y, Yamamoto H, Takeuchi H, Fujioka S, Hino T. Pulmonary delivery of insulin with nebulized DL-lactide/glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect. J Control Release. 1999;62(1-2):279-287.
    • (1999) J Control Release. , vol.62 , Issue.1-2 , pp. 279-287
    • Kawashima, Y.1    Yamamoto, H.2    Takeuchi, H.3    Fujioka, S.4    Hino, T.5
  • 158
    • 0037263890 scopus 로고    scopus 로고
    • Particle characteristics and lung deposition patterns in a human airway replica of a dry powder formulation of polylactic acid produced using supercritical fluid technology
    • Cheng YS, Yazzie D, Gao J, Muggli D, Etter J, Rosenthal GJ. Particle characteristics and lung deposition patterns in a human airway replica of a dry powder formulation of polylactic acid produced using supercritical fluid technology. J Aerosol Med. 2003;16(1):65-73.
    • (2003) J Aerosol Med. , vol.16 , Issue.1 , pp. 65-73
    • Cheng, Y.S.1    Yazzie, D.2    Gao, J.3    Muggli, D.4    Etter, J.5    Rosenthal, G.J.6
  • 159
    • 0031836411 scopus 로고    scopus 로고
    • Protective efficacy of mycobacterial 71-kDa cell wall associated protein using poly (DL-lactide-co-glycolide) microparticles as carrier vehicles
    • Dhiman N, Khuller GK. Protective efficacy of mycobacterial 71-kDa cell wall associated protein using poly (DL-lactide-co-glycolide) microparticles as carrier vehicles. FEMS Immunol Med Microbiol. 1998;21(1):19-28.
    • (1998) FEMS Immunol Med Microbiol. , vol.21 , Issue.1 , pp. 19-28
    • Dhiman, N.1    Khuller, G.K.2
  • 160
    • 0032509910 scopus 로고    scopus 로고
    • Relating the phagocytosis of microparticles by alveolar macrophages to surface chemistry: The effect of 1,2-dipalmitoylphosphatidylcholine
    • Evora C, Soriano I, Rogers RA, Shakesheff KN, Hanes J, Langer R. Relating the phagocytosis of microparticles by alveolar macrophages to surface chemistry: the effect of 1,2-dipalmitoylphosphatidylcholine. J Control Release. 1998;51(2-3):143-152.
    • (1998) J Control Release. , vol.51 , Issue.2-3 , pp. 143-152
    • Evora, C.1    Soriano, I.2    Rogers, R.A.3    Shakesheff, K.N.4    Hanes, J.5    Langer, R.6
  • 161
    • 0242584998 scopus 로고    scopus 로고
    • Large porous particle impingement on lung epithelial cell monolayers-toward improved particle characterization in the lung
    • Fiegel J, Ehrhardt C, Schaefer UF, Lehr CM, Hanes J. Large porous particle impingement on lung epithelial cell monolayers-toward improved particle characterization in the lung. Pharm Res. 2003;20(5): 788-796.
    • (2003) Pharm Res. , vol.20 , Issue.5 , pp. 788-796
    • Fiegel, J.1    Ehrhardt, C.2    Schaefer, U.F.3    Lehr, C.M.4    Hanes, J.5
  • 162
    • 0032903845 scopus 로고    scopus 로고
    • Ultrasonic atomization for spray drying: A versatile technique for the preparation of protein loaded biodegradable microspheres
    • Bittner B, Kissel T. Ultrasonic atomization for spray drying: a versatile technique for the preparation of protein loaded biodegradable microspheres. J Microencapsul. 1999;16(3):325-341.
    • (1999) J Microencapsul. , vol.16 , Issue.3 , pp. 325-341
    • Bittner, B.1    Kissel, T.2
  • 163
    • 0035937594 scopus 로고    scopus 로고
    • Mucoadhesive nanoparticulate systems for peptide drug delivery
    • Takeuchi H, Yamamoto H, Kawashima Y. Mucoadhesive nanoparticulate systems for peptide drug delivery. Adv Drug Deliv Rev. 2001; 47(1):39-54.
    • (2001) Adv Drug Deliv Rev. , vol.47 , Issue.1 , pp. 39-54
    • Takeuchi, H.1    Yamamoto, H.2    Kawashima, Y.3
  • 164
    • 0032580354 scopus 로고    scopus 로고
    • Drug delivery and targeting
    • Langer R. Drug delivery and targeting. Nature. 1998;392(Suppl 6679): 5-10.
    • (1998) Nature. , vol.392 , Issue.SUPPL. 6679 , pp. 5-10
    • Langer, R.1
  • 166
    • 10744227569 scopus 로고    scopus 로고
    • Large porous particles for pulmonary drug delivery
    • Edwards DA, Hanes J, Caponetti G, et al. Large porous particles for pulmonary drug delivery. Science. 1997;276(5320):1868-1871.
    • (1997) Science. , vol.276 , Issue.5320 , pp. 1868-1871
    • Edwards, D.A.1    Hanes, J.2    Caponetti, G.3
  • 167
    • 0026545368 scopus 로고
    • The macrophage capacity for phagocytosis
    • Cannon GJ, Swanson JA. The macrophage capacity for phagocytosis. J Cell Sci. 1992;101(Pt 4):907-913.
    • (1992) J Cell Sci. , vol.101 , Issue.PART 4 , pp. 907-913
    • Cannon, G.J.1    Swanson, J.A.2
  • 168
    • 0347021194 scopus 로고    scopus 로고
    • Alternative sugars as potential carriers for dry powder inhalations
    • Steckel H, Bolzen N. Alternative sugars as potential carriers for dry powder inhalations. Int J Pharm. 2004;270(1-2):297-306.
    • (2004) Int J Pharm. , vol.270 , Issue.1-2 , pp. 297-306
    • Steckel, H.1    Bolzen, N.2
  • 169
    • 0029918843 scopus 로고    scopus 로고
    • Pulmonary delivery of salmon calcitonin dry powders containing absorption enhancers in rats
    • Kobayashi S, Kondo S, Juni K. Pulmonary delivery of salmon calcitonin dry powders containing absorption enhancers in rats. Pharm Res. 1996;13(1):80-83.
    • (1996) Pharm Res. , vol.13 , Issue.1 , pp. 80-83
    • Kobayashi, S.1    Kondo, S.2    Juni, K.3
  • 170
    • 0029891659 scopus 로고    scopus 로고
    • Precipitation of proteins in supercritical carbon dioxide
    • Winters MA, Knutson BL, Debenedetti PG, et al. Precipitation of proteins in supercritical carbon dioxide. J Pharm Sci. 1996;85(6):586-594.
    • (1996) J Pharm Sci. , vol.85 , Issue.6 , pp. 586-594
    • Winters, M.A.1    Knutson, B.L.2    Debenedetti, P.G.3
  • 171
    • 0034988423 scopus 로고    scopus 로고
    • Dry powders of stable protein formulations from aqueous solutions prepared using supercritical CO(2)-assisted aerosolization
    • Sellers SP, Clark GS, Sievers RE, Carpenter JF. Dry powders of stable protein formulations from aqueous solutions prepared using supercritical CO(2)-assisted aerosolization. J Pharm Sci. 2001;90(6):785-797.
    • (2001) J Pharm Sci. , vol.90 , Issue.6 , pp. 785-797
    • Sellers, S.P.1    Clark, G.S.2    Sievers, R.E.3    Carpenter, J.F.4
  • 172
    • 0014903869 scopus 로고
    • Factors influencing the distortion of sex ratio in Aedes aegypti
    • Hickey WA. Factors influencing the distortion of sex ratio in Aedes aegypti. J Med Entomol. 1970;7(6):727-735.
    • (1970) J Med Entomol. , vol.7 , Issue.6 , pp. 727-735
    • Hickey, W.A.1
  • 173
    • 0033043629 scopus 로고    scopus 로고
    • Protein inhalation powders: Spray drying vs spray freeze drying
    • Maa YF, Nguyen PA, Sweeney T, Shire SJ, Hsu CC. Protein inhalation powders: spray drying vs spray freeze drying. Pharm Res. 1999;16(2): 249-254.
    • (1999) Pharm Res. , vol.16 , Issue.2 , pp. 249-254
    • Maa, Y.F.1    Nguyen, P.A.2    Sweeney, T.3    Shire, S.J.4    Hsu, C.C.5
  • 174
    • 0034952813 scopus 로고    scopus 로고
    • Nuclear translocation of lactosylated poly-L-lysine/cDNA complex in cystic fibrosis airway epithelial cells
    • Klink DT, Chao S, Glick MC, Scanlin TF. Nuclear translocation of lactosylated poly-L-lysine/cDNA complex in cystic fibrosis airway epithelial cells. Mol Ther. 2001;3(6):831-841.
    • (2001) Mol Ther. , vol.3 , Issue.6 , pp. 831-841
    • Klink, D.T.1    Chao, S.2    Glick, M.C.3    Scanlin, T.F.4
  • 175
    • 0031725355 scopus 로고    scopus 로고
    • A new powder design method to improve inhalation efficiency of pranlukast hydrate dry powder aerosols by surface modification with hydroxypropylmethylcellulose phthalate nanospheres
    • Kawashima Y, Serigano T, Hino T, Yamamoto H, Takeuchi H. A new powder design method to improve inhalation efficiency of pranlukast hydrate dry powder aerosols by surface modification with hydroxypropylmethylcellulose phthalate nanospheres. Pharm Res. 1998;15(11): 1748-1752.
    • (1998) Pharm Res. , vol.15 , Issue.11 , pp. 1748-1752
    • Kawashima, Y.1    Serigano, T.2    Hino, T.3    Yamamoto, H.4    Takeuchi, H.5
  • 176
    • 0029852699 scopus 로고    scopus 로고
    • Pharmaceutical applications of cyclodextrins. 2 In vivo drug delivery
    • Rajewski RA, Stella VJ. Pharmaceutical applications of cyclodextrins. 2 In vivo drug delivery. J Pharm Sci. 1996;85(11):1142-1169.
    • (1996) J Pharm Sci. , vol.85 , Issue.11 , pp. 1142-1169
    • Rajewski, R.A.1    Stella, V.J.2
  • 177
    • 0035816174 scopus 로고    scopus 로고
    • Sterically stabilized polyplex: Ligand-mediated activity
    • Woodle MC, Scaria P, Ganesh S, et al. Sterically stabilized polyplex: ligand-mediated activity. J Control Release. 2001;74(1-3):309-311.
    • (2001) J Control Release. , vol.74 , Issue.1-3 , pp. 309-311
    • Woodle, M.C.1    Scaria, P.2    Ganesh, S.3
  • 178
    • 0024512768 scopus 로고
    • Two-week aerosol inhalation study on polyethylene glycol (PEG) 3350 in F-344 rats
    • Klonne DR, Dodd DE, Losco PE, Troup CM, Tyler TR. Two-week aerosol inhalation study on polyethylene glycol (PEG) 3350 in F-344 rats. Drug Chem Toxicol. 1989;12(1):39-48.
    • (1989) Drug Chem Toxicol. , vol.12 , Issue.1 , pp. 39-48
    • Klonne, D.R.1    Dodd, D.E.2    Losco, P.E.3    Troup, C.M.4    Tyler, T.R.5
  • 179
    • 67049158572 scopus 로고    scopus 로고
    • Effects of hydroxylpropyl-betacyclodextrin on in vitro insulin stability
    • Zhang L, Zhu W, Song L, et al. Effects of hydroxylpropyl-betacyclodextrin on in vitro insulin stability. Int J Mol Sci. 2009;10(5): 2031-2040.
    • (2009) Int J Mol Sci. , vol.10 , Issue.5 , pp. 2031-2040
    • Zhang, L.1    Zhu, W.2    Song, L.3
  • 180
    • 0034886737 scopus 로고    scopus 로고
    • Lectin-functionalized liposomes for pulmonary drug delivery: Interaction with human alveolar epithelial cells
    • Bruck A, Abu-Dahab R, Borchard G, Schafer UF, Lehr CM. Lectin-functionalized liposomes for pulmonary drug delivery: interaction with human alveolar epithelial cells. J Drug Target. 2001;9(4):241-251.
    • (2001) J Drug Target. , vol.9 , Issue.4 , pp. 241-251
    • Bruck, A.1    Abu-Dahab, R.2    Borchard, G.3    Schafer, U.F.4    Lehr, C.M.5
  • 181
    • 0034945817 scopus 로고    scopus 로고
    • Lectin-functionalized liposomes for pulmonary drug delivery: Effect of nebulization on stability and bioadhesion
    • Abu-Dahab R, Schafer UF, Lehr CM. Lectin-functionalized liposomes for pulmonary drug delivery: effect of nebulization on stability and bioadhesion. Eur J Pharm Sci. 2001;14(1):37-46.
    • (2001) Eur J Pharm Sci. , vol.14 , Issue.1 , pp. 37-46
    • Abu-Dahab, R.1    Schafer, U.F.2    Lehr, C.M.3
  • 182
    • 0035713504 scopus 로고    scopus 로고
    • Lectin binding and endocytosis at the apical surface of human airway epithelia
    • Yi SM, Harson RE, Zabner J, Welsh MJ. Lectin binding and endocytosis at the apical surface of human airway epithelia. Gene Ther. 2001;8(24):1826-1832.
    • (2001) Gene Ther. , vol.8 , Issue.24 , pp. 1826-1832
    • Yi, S.M.1    Harson, R.E.2    Zabner, J.3    Welsh, M.J.4
  • 183
    • 62949248272 scopus 로고    scopus 로고
    • The cell-penetrating peptide octaarginine is a potent inhibitor of proteasome activities
    • Kloss A, Henklein P, Siele D, et al. The cell-penetrating peptide octaarginine is a potent inhibitor of proteasome activities. Eur J Pharm Biopharm. 2009;72(1):219-225.
    • (2009) Eur J Pharm Biopharm. , vol.72 , Issue.1 , pp. 219-225
    • Kloss, A.1    Henklein, P.2    Siele, D.3
  • 184
    • 0031605347 scopus 로고    scopus 로고
    • Targeting type II and Clara cells for adenovirus-mediated gene transfer using the surfactant protein B promoter
    • Strayer MS, Guttentag SH, Ballard PL. Targeting type II and Clara cells for adenovirus-mediated gene transfer using the surfactant protein B promoter. Am J Respir Cell Mol Biol. 1998;18(1):1-11.
    • (1998) Am J Respir Cell Mol Biol. , vol.18 , Issue.1 , pp. 1-11
    • Strayer, M.S.1    Guttentag, S.H.2    Ballard, P.L.3
  • 185
    • 0034031080 scopus 로고    scopus 로고
    • Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump
    • Goren D, Horowitz AT, Tzemach D, Tarshish M, Zalipsky S, Gabizon A. Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump. Clin Cancer Res. 2000; 6(5):1949-1957.
    • (2000) Clin Cancer Res. , vol.6 , Issue.5 , pp. 1949-1957
    • Goren, D.1    Horowitz, A.T.2    Tzemach, D.3    Tarshish, M.4    Zalipsky, S.5    Gabizon, A.6
  • 186
    • 0029688659 scopus 로고    scopus 로고
    • Epidermal growth factor mediated DNA delivery into lung cancer cells via the epidermal growth factor receptor
    • Cristiano RJ, Roth JA. Epidermal growth factor mediated DNA delivery into lung cancer cells via the epidermal growth factor receptor. Cancer Gene Ther. 1996;3(1):4-10.
    • (1996) Cancer Gene Ther. , vol.3 , Issue.1 , pp. 4-10
    • Cristiano, R.J.1    Roth, J.A.2
  • 187
    • 0042199010 scopus 로고    scopus 로고
    • Cell surface adherence and endocytosis of protein transduction domains
    • Lundberg M, Wikstrom S, Johansson M. Cell surface adherence and endocytosis of protein transduction domains. Mol Ther. 2003;8(1):143-150.
    • (2003) Mol Ther. , vol.8 , Issue.1 , pp. 143-150
    • Lundberg, M.1    Wikstrom, S.2    Johansson, M.3
  • 188
    • 0029982569 scopus 로고    scopus 로고
    • Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent
    • Derossi D, Calvet S, Trembleau A, Brunissen A, Chassaing G, Prochiantz A. Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent. J Biol Chem. 1996;271(30): 18188-18193.
    • (1996) J Biol Chem. , vol.271 , Issue.30 , pp. 18188-18193
    • Derossi, D.1    Calvet, S.2    Trembleau, A.3    Brunissen, A.4    Chassaing, G.5    Prochiantz, A.6
  • 189
    • 0344420207 scopus 로고    scopus 로고
    • Sorting motifs in receptor trafficking
    • Kurten RC. Sorting motifs in receptor trafficking. Adv Drug Deliv Rev. 2003;55(11):1405-1419.
    • (2003) Adv Drug Deliv Rev. , vol.55 , Issue.11 , pp. 1405-1419
    • Kurten, R.C.1
  • 190
    • 0035176318 scopus 로고    scopus 로고
    • Microtubule involvement in the intracellular dynamics for gene transfection mediated by cationic liposomes
    • Hasegawa S, Hirashima N, Nakanishi M. Microtubule involvement in the intracellular dynamics for gene transfection mediated by cationic liposomes. Gene Ther. 2001;8(21):1669-1673.
    • (2001) Gene Ther. , vol.8 , Issue.21 , pp. 1669-1673
    • Hasegawa, S.1    Hirashima, N.2    Nakanishi, M.3
  • 191
    • 17544368685 scopus 로고    scopus 로고
    • Multidrug resistance proteins: Role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
    • Leslie EM, Deeley RG, Cole SP. Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. Toxicol Appl Pharmacol. 2005;204(3):216-237.
    • (2005) Toxicol Appl Pharmacol. , vol.204 , Issue.3 , pp. 216-237
    • Leslie, E.M.1    Deeley, R.G.2    Cole, S.P.3
  • 192
    • 40949121607 scopus 로고    scopus 로고
    • ABC multidrug transporters: Structure, function and role in chemoresistance
    • Sharom FJ. ABC multidrug transporters: structure, function and role in chemoresistance. Pharmacogenomics. 2008;9(1):105-127.
    • (2008) Pharmacogenomics. , vol.9 , Issue.1 , pp. 105-127
    • Sharom, F.J.1
  • 193
    • 33644692006 scopus 로고    scopus 로고
    • Scientific perspectives on drug transporters and their role in drug interactions
    • Zhang L, Strong JM, Qiu W, Lesko LJ, Huang SM. Scientific perspectives on drug transporters and their role in drug interactions. Mol Pharm. 2006;3(1):62-69.
    • (2006) Mol Pharm. , vol.3 , Issue.1 , pp. 62-69
    • Zhang, L.1    Strong, J.M.2    Qiu, W.3    Lesko, L.J.4    Huang, S.M.5
  • 194
    • 0030862041 scopus 로고    scopus 로고
    • MDR1-Pgp 170 expression in human bronchus
    • Lechapt-Zalcman E, Hurbain I, Lacave R, et al. MDR1-Pgp 170 expression in human bronchus. Eur Respir J. 1997;10(8):1837-1843.
    • (1997) Eur Respir J. , vol.10 , Issue.8 , pp. 1837-1843
    • Lechapt-Zalcman, E.1    Hurbain, I.2    Lacave, R.3
  • 195
    • 0036260972 scopus 로고    scopus 로고
    • Multidrug resistance related molecules in human and murine lung
    • Scheffer GL, Pijnenborg AC, Smit EF, et al. Multidrug resistance related molecules in human and murine lung. J Clin Pathol. 2002; 55(5):332-339.
    • (2002) J Clin Pathol. , vol.55 , Issue.5 , pp. 332-339
    • Scheffer, G.L.1    Pijnenborg, A.C.2    Smit, E.F.3
  • 196
    • 0025105779 scopus 로고
    • Distribution of multi-drug resistance-associated P-glycoprotein in normal and neoplastic human tissues. Analysis with 3 monoclonal antibodies recognizing different epitopes of the P-glycoprotein molecule
    • van der Valk P, van Kalken CK, Ketelaars H, et al. Distribution of multi-drug resistance-associated P-glycoprotein in normal and neoplastic human tissues. Analysis with 3 monoclonal antibodies recognizing different epitopes of the P-glycoprotein molecule. Ann Oncol. 1990;1(1):56-64.
    • (1990) Ann Oncol. , vol.1 , Issue.1 , pp. 56-64
    • van der Valk, P.1    van Kalken, C.K.2    Ketelaars, H.3
  • 197
  • 198
    • 0037457802 scopus 로고    scopus 로고
    • Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview
    • Schinkel AH, Jonker JW. Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview. Adv Drug Deliv Rev. 2003;55(1):3-29.
    • (2003) Adv Drug Deliv Rev. , vol.55 , Issue.1 , pp. 3-29
    • Schinkel, A.H.1    Jonker, J.W.2
  • 199
    • 0036903656 scopus 로고    scopus 로고
    • Relationship between chemotherapy response of small cell lung cancer and P-glycoprotein or multidrug resistance-related protein expression
    • Hsia TC, Lin CC, Wang JJ, Ho ST, Kao A. Relationship between chemotherapy response of small cell lung cancer and P-glycoprotein or multidrug resistance-related protein expression. Lung. 2002;180(3): 173-179.
    • (2002) Lung. , vol.180 , Issue.3 , pp. 173-179
    • Hsia, T.C.1    Lin, C.C.2    Wang, J.J.3    Ho, S.T.4    Kao, A.5
  • 200
    • 0030775546 scopus 로고    scopus 로고
    • Induction by antitumoral drugs of proteins that functionally complement CFTR: A novel therapy for cystic fibrosis?
    • Lallemand JY, Stoven V, Annereau JP, et al. Induction by antitumoral drugs of proteins that functionally complement CFTR: a novel therapy for cystic fibrosis? Lancet. 1997;350(9079):711-712.
    • (1997) Lancet. , vol.350 , Issue.9079 , pp. 711-712
    • Lallemand, J.Y.1    Stoven, V.2    Annereau, J.P.3
  • 201
    • 23944447796 scopus 로고    scopus 로고
    • P-glycoprotein expression increases ATP release in respiratory cystic fibrosis cells
    • Naumann N, Siratska O, Gahr M, Rosen-Wolff A. P-glycoprotein expression increases ATP release in respiratory cystic fibrosis cells. J Cyst Fibros. 2005;4(3):157-168.
    • (2005) J Cyst Fibros. , vol.4 , Issue.3 , pp. 157-168
    • Naumann, N.1    Siratska, O.2    Gahr, M.3    Rosen-Wolff, A.4
  • 202
    • 53449102658 scopus 로고    scopus 로고
    • Chemotoxicity of doxorubicin and surface expression of P-glycoprotein (MDR1) is regulated by the Pseudomonas aeruginosa toxin Cif
    • Ye S, MacEachran DP, Hamilton JW, O'Toole GA, Stanton BA. Chemotoxicity of doxorubicin and surface expression of P-glycoprotein (MDR1) is regulated by the Pseudomonas aeruginosa toxin Cif. Am J Physiol Cell Physiol. 2008;295(3):C807-C818.
    • (2008) Am J Physiol Cell Physiol. , vol.295 , Issue.3
    • Ye, S.1    MacEachran, D.P.2    Hamilton, J.W.3    O'Toole, G.A.4    Stanton, B.A.5
  • 203
    • 33751511745 scopus 로고    scopus 로고
    • Diminished expression of multidrug resistance-associated protein 1 (MRP1) in bronchial epithelium of COPD patients
    • van der Deen M, Marks H, Willemse BW, et al. Diminished expression of multidrug resistance-associated protein 1 (MRP1) in bronchial epithelium of COPD patients. Virchows Arch. 2006;449(6):682-688.
    • (2006) Virchows Arch. , vol.449 , Issue.6 , pp. 682-688
    • van der Deen, M.1    Marks, H.2    Willemse, B.W.3
  • 204
    • 34247616480 scopus 로고    scopus 로고
    • Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels
    • Blokzijl H, Vander Borght S, Bok LI, et al. Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels. Inflamm Bowel Dis. 2007;13(6): 710-720.
    • (2007) Inflamm Bowel Dis. , vol.13 , Issue.6 , pp. 710-720
    • Blokzijl, H.1    vander Borght, S.2    Bok, L.I.3
  • 205
    • 0030823456 scopus 로고    scopus 로고
    • Expression of P-glycoprotein 170 in nasal mucosa may be increased with topical steroids
    • Henriksson G, Norlander T, Zheng X, Stierna P, Westrin KM. Expression of P-glycoprotein 170 in nasal mucosa may be increased with topical steroids. Am J Rhinol. 1997;11(4):317-321.
    • (1997) Am J Rhinol. , vol.11 , Issue.4 , pp. 317-321
    • Henriksson, G.1    Norlander, T.2    Zheng, X.3    Stierna, P.4    Westrin, K.M.5
  • 206
    • 0032933142 scopus 로고    scopus 로고
    • Dexamethasone modulation of multidrug transporters in normal tissues
    • Demeule M, Jodoin J, Beaulieu E, Brossard M, Beliveau R. Dexamethasone modulation of multidrug transporters in normal tissues. FEBS Lett. 1999;442(2-3):208-214.
    • (1999) FEBS Lett. , vol.442 , Issue.2-3 , pp. 208-214
    • Demeule, M.1    Jodoin, J.2    Beaulieu, E.3    Brossard, M.4    Beliveau, R.5
  • 207
    • 33748740652 scopus 로고    scopus 로고
    • Single high dose dexamethasone treatment decreases the pathological score and increases the survival rate of paraquat-intoxicated rats
    • Dinis-Oliveira RJ, Duarte JA, Remiao F, Sanchez-Navarro A, Bastos ML, Carvalho F. Single high dose dexamethasone treatment decreases the pathological score and increases the survival rate of paraquat-intoxicated rats. Toxicology. 2006;227(1-2):73-85.
    • (2006) Toxicology. , vol.227 , Issue.1-2 , pp. 73-85
    • Dinis-Oliveira, R.J.1    Duarte, J.A.2    Remiao, F.3    Sanchez-Navarro, A.4    Bastos, M.L.5    Carvalho, F.6
  • 208
    • 12644278301 scopus 로고    scopus 로고
    • Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
    • Sparreboom A, van Asperen J, Mayer U, et al. Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine. Proc Natl Acad Sci U S A. 1997;94(5):2031-2035.
    • (1997) Proc Natl Acad Sci U S A. , vol.94 , Issue.5 , pp. 2031-2035
    • Sparreboom, A.1    van Asperen, J.2    Mayer, U.3
  • 209
    • 0037305372 scopus 로고    scopus 로고
    • Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues
    • Langmann T, Mauerer R, Zahn A, et al. Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues. Clin Chem. 2003;49(2): 230-238.
    • (2003) Clin Chem. , vol.49 , Issue.2 , pp. 230-238
    • Langmann, T.1    Mauerer, R.2    Zahn, A.3
  • 210
    • 0030841332 scopus 로고    scopus 로고
    • Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines
    • Kool M, de Haas M, Scheffer GL, et al. Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res. 1997;57(16):3537-3547.
    • (1997) Cancer Res. , vol.57 , Issue.16 , pp. 3537-3547
    • Kool, M.1    de Haas, M.2    Scheffer, G.L.3
  • 211
    • 9244261944 scopus 로고    scopus 로고
    • Tissue distribution of the multidrug resistance protein
    • Flens MJ, Zaman GJ, van der Valk P, et al. Tissue distribution of the multidrug resistance protein. Am J Pathol. 1996;148(4): 1237-1247.
    • (1996) Am J Pathol. , vol.148 , Issue.4 , pp. 1237-1247
    • Flens, M.J.1    Zaman, G.J.2    van der Valk, P.3
  • 212
    • 0031893212 scopus 로고    scopus 로고
    • Different pattern of MRP localization in ciliated and basal cells from human bronchial epithelium
    • Brechot JM, Hurbain I, Fajac A, Daty N, Bernaudin JF. Different pattern of MRP localization in ciliated and basal cells from human bronchial epithelium. J Histochem Cytochem. 1998;46(4):513-517.
    • (1998) J Histochem Cytochem. , vol.46 , Issue.4 , pp. 513-517
    • Brechot, J.M.1    Hurbain, I.2    Fajac, A.3    Daty, N.4    Bernaudin, J.F.5
  • 213
    • 35548940659 scopus 로고    scopus 로고
    • Cigarette smoke extract affects functional activity of MRP1 in bronchial epithelial cells
    • van der Deen M, de Vries EG, Visserman H, et al. Cigarette smoke extract affects functional activity of MRP1 in bronchial epithelial cells. J Biochem Mol Toxicol. 2007;21(5):243-251.
    • (2007) J Biochem Mol Toxicol. , vol.21 , Issue.5 , pp. 243-251
    • van der Deen, M.1    de Vries, E.G.2    Visserman, H.3
  • 214
    • 54949123797 scopus 로고    scopus 로고
    • Effect of COPD treatments on MRP1-mediated transport in bronchial epithelial cells
    • van der Deen M, Homan S, Timmer-Bosscha H, et al. Effect of COPD treatments on MRP1-mediated transport in bronchial epithelial cells. Int J Chron Obstruct Pulmon Dis. 2008;3(3):469-475.
    • (2008) Int J Chron Obstruct Pulmon Dis. , vol.3 , Issue.3 , pp. 469-475
    • van der Deen, M.1    Homan, S.2    Timmer-Bosscha, H.3
  • 215
    • 33751578245 scopus 로고    scopus 로고
    • Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: A resource for investigations into drug disposition
    • Bleasby K, Castle JC, Roberts CJ, et al. Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: a resource for investigations into drug disposition. Xenobiotica. 2006; 36(10-11):963-988.
    • (2006) Xenobiotica. , vol.36 , Issue.10-11 , pp. 963-988
    • Bleasby, K.1    Castle, J.C.2    Roberts, C.J.3
  • 216
    • 35648938725 scopus 로고    scopus 로고
    • The effect of corticosteroids on the disposal of long-acting beta2-agonists by airway smooth muscle cells
    • Horvath G, Mendes ES, Schmid N, et al. The effect of corticosteroids on the disposal of long-acting beta2-agonists by airway smooth muscle cells. J Allergy Clin Immunol. 2007;120(5):1103-1109.
    • (2007) J Allergy Clin Immunol. , vol.120 , Issue.5 , pp. 1103-1109
    • Horvath, G.1    Mendes, E.S.2    Schmid, N.3
  • 217
    • 21844457187 scopus 로고    scopus 로고
    • Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium
    • Lips KS, Volk C, Schmitt BM, et al. Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium. Am J Respir Cell Mol Biol. 2005;33(1):79-88.
    • (2005) Am J Respir Cell Mol Biol. , vol.33 , Issue.1 , pp. 79-88
    • Lips, K.S.1    Volk, C.2    Schmitt, B.M.3
  • 218
    • 33846100266 scopus 로고    scopus 로고
    • Epithelial organic cation transporters ensure pH-dependent drug absorption in the airway
    • Horvath G, Schmid N, Fragoso MA, et al. Epithelial organic cation transporters ensure pH-dependent drug absorption in the airway. Am J Respir Cell Mol Biol. 2007;36(1):53-60.
    • (2007) Am J Respir Cell Mol Biol. , vol.36 , Issue.1 , pp. 53-60
    • Horvath, G.1    Schmid, N.2    Fragoso, M.A.3
  • 219
    • 48749124897 scopus 로고    scopus 로고
    • The epithelial cholinergic system of the airways
    • Kummer W, Lips KS, Pfeil U. The epithelial cholinergic system of the airways. Histochem Cell Biol. 2008;130(2):219-234.
    • (2008) Histochem Cell Biol. , vol.130 , Issue.2 , pp. 219-234
    • Kummer, W.1    Lips, K.S.2    Pfeil, U.3
  • 220
    • 33845920612 scopus 로고    scopus 로고
    • Role of acetylcholine and muscarinic receptors in serotonin-induced bronchoconstriction in the mouse
    • Kummer W, Wiegand S, Akinci S, et al. Role of acetylcholine and muscarinic receptors in serotonin-induced bronchoconstriction in the mouse. J Mol Neurosci. 2006;30(1-2):67-68.
    • (2006) J Mol Neurosci. , vol.30 , Issue.1-2 , pp. 67-68
    • Kummer, W.1    Wiegand, S.2    Akinci, S.3
  • 221
    • 1542345031 scopus 로고    scopus 로고
    • Molecular mechanisms of pulmonary peptidomimetic drug and peptide transport
    • Groneberg DA, Fischer A, Chung KF, Daniel H. Molecular mechanisms of pulmonary peptidomimetic drug and peptide transport. Am J Respir Cell Mol Biol. 2004;30(3):251-260.
    • (2004) Am J Respir Cell Mol Biol. , vol.30 , Issue.3 , pp. 251-260
    • Groneberg, D.A.1    Fischer, A.2    Chung, K.F.3    Daniel, H.4
  • 222
    • 43149086651 scopus 로고    scopus 로고
    • hPEPT1 is responsible for uptake and transport of Gly-Sar in the human bronchial airway epithelial cell-line Calu-3
    • Sondergaard HB, Brodin B, Nielsen CU. hPEPT1 is responsible for uptake and transport of Gly-Sar in the human bronchial airway epithelial cell-line Calu-3. Pflugers Arch. 2008;456(3):611-622.
    • (2008) Pflugers Arch. , vol.456 , Issue.3 , pp. 611-622
    • Sondergaard, H.B.1    Brodin, B.2    Nielsen, C.U.3
  • 223
    • 0036144689 scopus 로고    scopus 로고
    • Distribution and function of the peptide transporter PEPT2 in normal and cystic fibrosis human lung
    • Groneberg DA, Eynott PR, Doring F, et al. Distribution and function of the peptide transporter PEPT2 in normal and cystic fibrosis human lung. Thorax. 2002;57(1):55-60.
    • (2002) Thorax. , vol.57 , Issue.1 , pp. 55-60
    • Groneberg, D.A.1    Eynott, P.R.2    Doring, F.3
  • 224
    • 85047683608 scopus 로고    scopus 로고
    • RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models
    • Endter S, Francombe D, Ehrhardt C, Gumbleton M. RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models. J Pharm Pharmacol. 2009;61(5):583-591.
    • (2009) J Pharm Pharmacol. , vol.61 , Issue.5 , pp. 583-591
    • Endter, S.1    Francombe, D.2    Ehrhardt, C.3    Gumbleton, M.4
  • 225
    • 0029919966 scopus 로고    scopus 로고
    • Molecular cloning and tissue distribution of rat peptide transporter PEPT2
    • Saito H, Terada T, Okuda M, Sasaki S, Inui K. Molecular cloning and tissue distribution of rat peptide transporter PEPT2. Biochim Biophys Acta. 1996;1280(2):173-177.
    • (1996) Biochim Biophys Acta. , vol.1280 , Issue.2 , pp. 173-177
    • Saito, H.1    Terada, T.2    Okuda, M.3    Sasaki, S.4    Inui, K.5
  • 226
    • 77951277135 scopus 로고    scopus 로고
    • Drug transporters in the lung-do they play a role in the biopharmaceutics of inhaled drugs?
    • Bosquillon C. Drug transporters in the lung-do they play a role in the biopharmaceutics of inhaled drugs? J Pharm Sci. 2010;99(5): 2240-2255.
    • (2010) J Pharm Sci. , vol.99 , Issue.5 , pp. 2240-2255
    • Bosquillon, C.1
  • 227
    • 7644222033 scopus 로고    scopus 로고
    • The multispecific organic anion transporter family: Properties and pharmacological significance
    • Miyazaki H, Sekine T, Endou H. The multispecific organic anion transporter family: properties and pharmacological significance. Trends Pharmacol Sci. 2004;25(12):654-662.
    • (2004) Trends Pharmacol Sci. , vol.25 , Issue.12 , pp. 654-662
    • Miyazaki, H.1    Sekine, T.2    Endou, H.3
  • 228
    • 48749112588 scopus 로고    scopus 로고
    • Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family
    • Hagenbuch B, Gui C. Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family. Xenobiotica. 2008; 38(7-8):778-801.
    • (2008) Xenobiotica. , vol.38 , Issue.7-8 , pp. 778-801
    • Hagenbuch, B.1    Gui, C.2
  • 229
    • 0242497239 scopus 로고    scopus 로고
    • Molecular characterization of human and rat organic anion transporter OATP-D
    • Adachi H, Suzuki T, Abe M, et al. Molecular characterization of human and rat organic anion transporter OATP-D. Am J Physiol Renal Physiol. 2003;285(6):F1188-F1197.
    • (2003) Am J Physiol Renal Physiol. , vol.285 , Issue.6
    • Adachi, H.1    Suzuki, T.2    Abe, M.3
  • 230
    • 33646576582 scopus 로고    scopus 로고
    • Development of a respirable, sustained release microcarrier for 5-fluorouracil II: In vitro and in vivo optimization of lipid coated nanoparticles
    • Hitzman CJ, Elmquist WF, Wiedmann TS. Development of a respirable, sustained release microcarrier for 5-fluorouracil II: In vitro and in vivo optimization of lipid coated nanoparticles. J Pharm Sci. 2006; 95(5):1127-1143.
    • (2006) J Pharm Sci. , vol.95 , Issue.5 , pp. 1127-1143
    • Hitzman, C.J.1    Elmquist, W.F.2    Wiedmann, T.S.3
  • 231
    • 33646564421 scopus 로고    scopus 로고
    • Development of a respirable, sustained release microcarrier for 5-fluorouracil I: In vitro assessment of liposomes, microspheres, and lipid coated nanoparticles
    • Hitzman CJ, Elmquist WF, Wattenberg LW, Wiedmann TS. Development of a respirable, sustained release microcarrier for 5-fluorouracil I: In vitro assessment of liposomes, microspheres, and lipid coated nanoparticles. J Pharm Sci. 2006;95(5): 1114-1126.
    • (2006) J Pharm Sci. , vol.95 , Issue.5 , pp. 1114-1126
    • Hitzman, C.J.1    Elmquist, W.F.2    Wattenberg, L.W.3    Wiedmann, T.S.4
  • 232
    • 28744444691 scopus 로고    scopus 로고
    • Paclitaxel-loaded poly(gammaglutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system for the treatment of liver cancer
    • Liang HF, Chen CT, Chen SC, et al. Paclitaxel-loaded poly(gammaglutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system for the treatment of liver cancer. Biomaterials. 2006;27(9): 2051-2059.
    • (2006) Biomaterials , vol.27 , Issue.9 , pp. 2051-2059
    • Liang, H.F.1    Chen, C.T.2    Chen, S.C.3
  • 234
    • 33646389800 scopus 로고    scopus 로고
    • Long circulating poly(ethylene glycol)-decorated lipid nanocapsules deliver docetaxel to solid tumors
    • Khalid MN, Simard P, Hoarau D, Dragomir A, Leroux JC. Long circulating poly(ethylene glycol)-decorated lipid nanocapsules deliver docetaxel to solid tumors. Pharm Res. 2006;23(4):752-758.
    • (2006) Pharm Res. , vol.23 , Issue.4 , pp. 752-758
    • Khalid, M.N.1    Simard, P.2    Hoarau, D.3    Dragomir, A.4    Leroux, J.C.5
  • 235
    • 34548385316 scopus 로고    scopus 로고
    • Nanoparticle albumin-bound paclitaxel: A novel Cremphor-EL-free formulation of paclitaxel
    • Stinchcombe TE. Nanoparticle albumin-bound paclitaxel: a novel Cremphor-EL-free formulation of paclitaxel. Nanomedicine (Lond). 2007;2(4):415-423.
    • (2007) Nanomedicine (Lond) , vol.2 , Issue.4 , pp. 415-423
    • Stinchcombe, T.E.1
  • 236
    • 34548672585 scopus 로고    scopus 로고
    • The new ATS/ERS guidelines for assessing the spirometric severity of restrictive lung disease differ from previous standards
    • Aggarwal AN, Agarwal R. The new ATS/ERS guidelines for assessing the spirometric severity of restrictive lung disease differ from previous standards. Respirology. 2007;12(5):759-762.
    • (2007) Respirology , vol.12 , Issue.5 , pp. 759-762
    • Aggarwal, A.N.1    Agarwal, R.2
  • 237
    • 34848842825 scopus 로고    scopus 로고
    • Impact of the new ATS/ERS pulmonary function test interpretation guidelines
    • Kreider ME, Grippi MA. Impact of the new ATS/ERS pulmonary function test interpretation guidelines. Respir Med. 2007;101(11): 2336-2342.
    • (2007) Respir Med. , vol.101 , Issue.11 , pp. 2336-2342
    • Kreider, M.E.1    Grippi, M.A.2
  • 238
    • 0346515662 scopus 로고    scopus 로고
    • Novel vitamin E analogue decreases syngeneic mouse mammary tumor burden and reduces lung metastasis
    • Lawson KA, Anderson K, Menchaca M, et al. Novel vitamin E analogue decreases syngeneic mouse mammary tumor burden and reduces lung metastasis. Mol Cancer Ther. 2003;2(5):437-444.
    • (2003) Mol Cancer Ther. , vol.2 , Issue.5 , pp. 437-444
    • Lawson, K.A.1    Anderson, K.2    Menchaca, M.3
  • 239
    • 18244366079 scopus 로고    scopus 로고
    • Anticancer effect of an alpha-TEA liposome aerosol
    • Knight V. Anticancer effect of an alpha-TEA liposome aerosol. Exp Biol Med (Maywood). 2005;230(5):291.
    • (2005) Exp Biol Med (Maywood) , vol.230 , Issue.5 , pp. 291
    • Knight, V.1
  • 241
    • 33646486081 scopus 로고    scopus 로고
    • Gemcitabine aerosol: In vitro antitumor activity and deposition imaging for preclinical safety assessment in baboons
    • Gagnadoux F, Leblond V, Vecellio L, et al. Gemcitabine aerosol: in vitro antitumor activity and deposition imaging for preclinical safety assessment in baboons. Cancer Chemother Pharmacol. 2006;58(2): 237-244.
    • (2006) Cancer Chemother Pharmacol. , vol.58 , Issue.2 , pp. 237-244
    • Gagnadoux, F.1    Leblond, V.2    Vecellio, L.3
  • 242
    • 21344435041 scopus 로고    scopus 로고
    • Safety of pulmonary administration of gemcitabine in rats
    • Gagnadoux F, Le Pape A, Urban T, et al. Safety of pulmonary administration of gemcitabine in rats. J Aerosol Med. 2005;18(2):198-206.
    • (2005) J Aerosol Med. , vol.18 , Issue.2 , pp. 198-206
    • Gagnadoux, F.1    Le Pape, A.2    Urban, T.3
  • 243
    • 82955207116 scopus 로고    scopus 로고
    • Aerosolized gemcitabine in patients with carcinoma of the lung: Feasibility and safety study
    • Lemarie E, Vecellio L, Hureaux J, et al. Aerosolized gemcitabine in patients with carcinoma of the lung: feasibility and safety study. J Aerosol Med Pulm Drug Deliv. 2011;24(6):261-270.
    • (2011) J Aerosol Med Pulm Drug Deliv. , vol.24 , Issue.6 , pp. 261-270
    • Lemarie, E.1    Vecellio, L.2    Hureaux, J.3
  • 244
    • 43949144185 scopus 로고    scopus 로고
    • Pulmonary gemcitabine delivery for treating lung cancer: Pharmacokinetics and acute lung injury aspects in animals
    • Min R, Li T, Du J, Zhang Y, Guo J, Lu WL. Pulmonary gemcitabine delivery for treating lung cancer: pharmacokinetics and acute lung injury aspects in animals. Can J Physiol Pharmacol. 2008;86(5): 288-298.
    • (2008) Can J Physiol Pharmacol. , vol.86 , Issue.5 , pp. 288-298
    • Min, R.1    Li, T.2    Du, J.3    Zhang, Y.4    Guo, J.5    Lu, W.L.6
  • 245
    • 4944238261 scopus 로고    scopus 로고
    • Interstitial lung disease associated with drug therapy
    • Camus P, Kudoh S, Ebina M. Interstitial lung disease associated with drug therapy. Br J Cancer. 2004;91 Suppl 2:S18-S23.
    • (2004) Br J Cancer , vol.91 , Issue.SUPPL. 2
    • Camus, P.1    Kudoh, S.2    Ebina, M.3
  • 246
    • 4944255601 scopus 로고    scopus 로고
    • Interstitial lung disease in patients with non-small-cell lung cancer: Causes, mechanisms and management
    • Camus P. Interstitial lung disease in patients with non-small-cell lung cancer: causes, mechanisms and management. Br J Cancer. 2004;91 Suppl 2:S1-S2.
    • (2004) Br J Cancer , vol.91 , Issue.SUPPL. 2
    • Camus, P.1
  • 247
    • 4444231773 scopus 로고    scopus 로고
    • Interstitial lung disease induced by drugs and radiation
    • Camus P, Fanton A, Bonniaud P, Camus C, Foucher P. Interstitial lung disease induced by drugs and radiation. Respiration. 2004;71(4): 301-326.
    • (2004) Respiration , vol.71 , Issue.4 , pp. 301-326
    • Camus, P.1    Fanton, A.2    Bonniaud, P.3    Camus, C.4    Foucher, P.5
  • 249
    • 0030996855 scopus 로고    scopus 로고
    • Fatal pulmonary toxicity resulting from treatment with gemcitabine
    • Pavlakis N, Bell DR, Millward MJ, Levi JA. Fatal pulmonary toxicity resulting from treatment with gemcitabine. Cancer. 1997;80(2): 286-291.
    • (1997) Cancer , vol.80 , Issue.2 , pp. 286-291
    • Pavlakis, N.1    Bell, D.R.2    Millward, M.J.3    Levi, J.A.4
  • 250
    • 0142029623 scopus 로고    scopus 로고
    • Fatal pulmonary toxicity in a patient treated with gefitinib for nonsmall cell lung cancer after previous hemolytic-uremic syndrome due to gemcitabine
    • Rabinowits G, Herchenhorn D, Rabinowits M, Weatge D, Torres W. Fatal pulmonary toxicity in a patient treated with gefitinib for nonsmall cell lung cancer after previous hemolytic-uremic syndrome due to gemcitabine. Anticancer Drugs. 2003;14(8):665-668.
    • (2003) Anticancer Drugs , vol.14 , Issue.8 , pp. 665-668
    • Rabinowits, G.1    Herchenhorn, D.2    Rabinowits, M.3    Weatge, D.4    Torres, W.5
  • 251
    • 0041887251 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase inhibition augments a murine model of pulmonary fibrosis
    • Suzuki H, Aoshiba K, Yokohori N, Nagai A. Epidermal growth factor receptor tyrosine kinase inhibition augments a murine model of pulmonary fibrosis. Cancer Res. 2003;63(16):5054-5059.
    • (2003) Cancer Res. , vol.63 , Issue.16 , pp. 5054-5059
    • Suzuki, H.1    Aoshiba, K.2    Yokohori, N.3    Nagai, A.4
  • 252
    • 42749089385 scopus 로고    scopus 로고
    • Inhalable liposomal formulation for vasoactive intestinal peptide
    • Hajos F, Stark B, Hensler S, Prassl R, Mosgoeller W. Inhalable liposomal formulation for vasoactive intestinal peptide. Int J Pharm. 2008;357(1-2):286-294.
    • (2008) Int J Pharm. , vol.357 , Issue.1-2 , pp. 286-294
    • Hajos, F.1    Stark, B.2    Hensler, S.3    Prassl, R.4    Mosgoeller, W.5
  • 253
    • 4344571205 scopus 로고    scopus 로고
    • Enhancement of the efficacy of chemotherapy for lung cancer by simultaneous suppression of multidrug resistance and antiapoptotic cellular defense: Novel multicomponent delivery system
    • Pakunlu RI, Wang Y, Tsao W, Pozharov V, Cook TJ, Minko T. Enhancement of the efficacy of chemotherapy for lung cancer by simultaneous suppression of multidrug resistance and antiapoptotic cellular defense: novel multicomponent delivery system. Cancer Res. 2004;64(17):6214-6224.
    • (2004) Cancer Res. , vol.64 , Issue.17 , pp. 6214-6224
    • Pakunlu, R.I.1    Wang, Y.2    Tsao, W.3    Pozharov, V.4    Cook, T.J.5    Minko, T.6
  • 254
    • 0037336279 scopus 로고    scopus 로고
    • Simultaneous modulation of multidrug resistance and antiapoptotic cellular defense by MDR1 and BCL-2 targeted antisense oligonucleotides enhances the anticancer efficacy of doxorubicin
    • Pakunlu RI, Cook TJ, Minko T. Simultaneous modulation of multidrug resistance and antiapoptotic cellular defense by MDR1 and BCL-2 targeted antisense oligonucleotides enhances the anticancer efficacy of doxorubicin. Pharm Res. 2003;20(3):351-359.
    • (2003) Pharm Res. , vol.20 , Issue.3 , pp. 351-359
    • Pakunlu, R.I.1    Cook, T.J.2    Minko, T.3
  • 255
    • 33747877757 scopus 로고    scopus 로고
    • In vitro and in vivo intracellular liposomal delivery of antisense oligonucleotides and anticancer drug
    • Pakunlu RI, Wang Y, Saad M, Khandare JJ, Starovoytov V, Minko T. In vitro and in vivo intracellular liposomal delivery of antisense oligonucleotides and anticancer drug. J Control Release. 2006;114(2): 153-162.
    • (2006) J Control Release , vol.114 , Issue.2 , pp. 153-162
    • Pakunlu, R.I.1    Wang, Y.2    Saad, M.3    Khandare, J.J.4    Starovoytov, V.5    Minko, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.