Long circulating poly(ethylene glycol)-decorated lipid nanocapsules deliver docetaxel to solid tumors

Pharmaceutical Research

Volumn 23, Issue 4, 2006, Pages 752-758

  Khalid, Mohamed Nabil ^a   Simard, Pierre ^a   Hoarau, Didier ^b   Dragomir, Alice ^a   Leroux, Jean Christophe ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b Ethypharm Inc   (Canada)

Author keywords

Docetaxel; Drug targeting; Nanocapsules; Pharmacokinetics; Poly(ethylene glycol)

Indexed keywords

CARBON 14; DOCETAXEL; HYDROGENATED SOYBEAN PHOSPHATIDYLCHOLINE; LIPID; MACROGOL 2000; MACROGOL DERIVATIVE; NANOCAPSULE; PHOSPHATIDYLCHOLINE; POLYETHYLENEGLYCOL 600 12 HYDROXYSTEARATE; TRIOCTANOIN; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CANCER MODEL; COLON ADENOCARCINOMA; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG TARGETING; DRUG TISSUE LEVEL; EVALUATION; FEMALE; HYDROPHOBICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOLID TUMOR;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AREA UNDER CURVE; CAPSULES; CELL LINE, TUMOR; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EXCIPIENTS; FEMALE; HALF-LIFE; HUMANS; LIPIDS; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; PARTICLE SIZE; POLYETHYLENE GLYCOLS; TAXOIDS; TISSUE DISTRIBUTION;

EID: 33646389800     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-9662-5     Document Type: Article

References (35)

1. D. C. Drummond O. Meyer K. Hong D. B. Kirpotin D. Papahadjopoulos 1999 Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors Pharmacol. Rev. 51 691 743
2. I. Brigger C. Dubernet P. Couvreur 2002 Nanoparticles in cancer therapy and diagnosis Adv. Drug Deliv. Rev. 54 631 651
3. M. C. Jones J. C. Leroux 1999 Polymeric micelles-a new generation of colloidal drug carriers Eur. J. Pharm. Biopharm. 48 101 111
4. S. M. Moghimi A. C. Hunt J. C. Murray 2001 Long-circulating and target-specific nanoparticles: theory to practice Pharmacol. Rev. 53 283 318
5. D. Papahadjopoulos T. M. Allen A. Gabizon E. Mayhew K. Matthay S. K. Huang K. D. Lee M. C. Woodle D. D. Lasic C. Redemann F. J. Martin 1991 Sterically stabilized liposomes: improvement in pharmacokinetics and antitumor therapeutic efficacy Proc. Natl. Acad. Sci. U.S.A. 88 11460 11464
6. M. S. Webb D. Saxon F. M. P. Wong H. J. Lim Z. Wang M. B. Bally L. S. L. Choi P. R. Cullis L. D. Mayer 1998 Comparison of different hydrophobic anchors conjugated to poly(ethylene glycol): effects on the pharmacokinetics of liposomal vincristine Biochim. Biophys. Acta 1372 272 282
7. R. Gref Y. Minamitake M. T. Peracchia V. S. Trubetskoy V. Torchilin R. Langer 1994 Biodegradable long circulating polymeric nanospheres Science 263 1600 1603
8. R. Duncan S. Gac-Breton R. Keane R. Musila Y. N. Sat R. Satchi F. Searle 2001 Polymer-drug conjugates, PDEPT and PELT: basic principles for design and transfer from the laboratory to the clinic J. Control. Release 74 135 146
9. F. Yuan M. Leunig S. K. Huang D. A. Berk D. Papahadjopoulos R. K. Jain 1994 Microvascular permeability and interstitial penetration of sterically stabilized (Stealth) liposomes in a human tumor xenograft Cancer Res. 54 3352 3356
10. R. K. Jain 1997 Delivery of molecular and cellular medicine to solid tumors Adv. Drug Deliv. Rev. 26 71 90
11. N. Z. Wu D. Da T. L. Rudoll D. Needham A. R. Whorton M. W. Dewhirst 1993 Increased microvascular permeability contributes to preferential accumulation of stealth liposomes in tumor tissue Cancer Res. 53 3765 3770
12. S. C. Kim D. W. Kim Y. H. Shim J. S. Bang H. S. Oh S. W. Kim M. H. Seo 2001 In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy J. Control. Release 72 191 202
13. D. Le Garrec S. Gori L. Luo D. Lessard D. C. Smith M. A. Yessine M. Ranger J. C. Leroux 2004 Poly(N-vinylpyrrolidone)-block-poly(d,l-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation J. Control. Release 99 83 101
14. T. Y. Kim D. W. Kim J. Y. Chung S. G. Shin S. C. Kim D. S. Heo N. K. Kim Y. J. Bang 2004 Phase I and pharmacokinetic stidy of Genexol-PM, a Cremophor free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies Clin. Cancer Res. 10 3708 3716
15. A. Sharma E. Mayhew L. Bolcsak C. Cavanaugh P. Harmon A. S. Janoff J. Bernacki 1997 Activity of paclitaxel liposome formulations against human ovarian tumor xenograft Int. J. Cancer 71 103 107
16. P. P. Constantinides A. Tustian D. R. Kessler 2004 Tocol emulsions for drug solubilization and parenteral delivery Adv. Drug Deliv. Rev. 56 1243 1255
17. B. T. Hill R. D. H. Whelan S. A. Shellard S. [tmp] McClean L. K. Hosking 1994 Differential cytotoxic effects of docetaxel in a range of mammalian tumor cell lines and certain drug resistant sublines in vitro Invest. New Drugs 12 169 182
18. M. C. Bissery D. Guénard F. Guéritte-Voegelein F. Lavelle 1991 Experimental antitumor activity of Taxotere (RP 56976, NSC 628503), a Taxol analogue Cancer Res. 5 4845 4852
19. A. J. Ten Tije J. Verweij W. J. Loos A. Sparreboom 2003 Pharmacological effects of formulation vehicles-implications for cancer chemotherapy Clin. Pharmacokinet. 42 665 685
20. D. Le Garrec M. Ranger J. C. Leroux 2004 Micelles in anticancer drug delivery Am. J. Drug Deliv. 2 15 42
21. J. Szebeni 2001 Complement activation-related pseudoallergy caused by liposomes, micellar carriers of intravenous drugs and radiocontrast agents Crit. Rev. Ther. Drug Carrier Syst. 18 567 606
22. N. Kang M. E. Perron R. E. Prud'Homme Y. Zhang G. Gaucher J. C. Leroux 2005 Stereocomplex block copolymer micelles: core-shell structures with enhanced stability Nano Lett. 5 315 319
23. X. Zhang H. M. Burt G. Mangold D. Dexter D. Von Hoff L. Mayer W. L. Hunter 1997 Anti-tumor efficacy and biodistribution of intravenous polymeric micellar paclitaxel Anti-Cancer Drugs 8 686 701
24. X. Shuai T. Merdan A. K. Schaper F. Xi T. Kissel 2004 Core-cross-linked polymeric micelles as paclitaxel carriers Bioconjug. Chem. 15 441 448
25. J. L. Liu C. Allen 2004 Polymer-drug compatibility: a guide to the development of delivery systems for the anticancer agent, ellipticine J. Pharm. Sci. 93 132 143
26. T. Hamaguchi Y. Matsumara M. Suzuki K. Shimizu R. Goda I. Nakamura I. Nakatomi M. Yokoyama K. Kataoka T. Kakizoe 2005 NK105, a paclitaxel- incorporating micellar nanoparticle formulation can extend in vivo antitumor activity and reduce the neurotoxicity of paclitaxel Br. J. Cancer 92 1240 1246
27. N. K. Ibrahim N. Desai S. Legha P. Soon-Shiong R. L. Theriault E. Rivera B. Esmaeli S. E. Ring A. Bedikian G. N. Hortobayi J. A. Ellerhost 2002 Phase I and pharmacokinetic study of ABI-007, a cremophor-free protein stabilized, nanoparticle formulation of paclitaxel Clin. Cancer Res. 8 1038 1044
28. J. W. Singer B. Baker P. De Vries A. Kumar S. Shaffer E. Vawter M. Bolton P. Garzone 2003 Poly-(l)-glutamic acid-paclitaxel (CT-2103) [XYOTAX], a biodegradable polymeric drug conjugate: characterization, preclinical pharmacology, and preliminary clinical data H. Maeda A. Kabanov K. Kataoka T. Okano Polymer Drugs in the Clinical Stage Kluwer Academic/Plenum Publishers New York 81 99
29. D. Hoarau P. Delmas S. David E. Roux J. C. Leroux 2004 Novel long-circulating lipid nanocapsules Pharm. Res. 21 1783 1789
30. B. Heurtault P. Saulnier B. Pech J. E. Proust J. P. Benoit 2002 A novel phase inversion-based process for the preparation of lipid nanocarriers Pharm. Res. 19 875 880
31. P. S. Uster T. M. Allen B. E. Daniel C. J. Mendez M. S. Newman G. Z. Zhu 1996 Insertion of poly(ethylene glycol) derivatized phospholipid into pre-formed liposomes results in prolonged in vivo circulation time FEBS Lett. 386 243 246
32. M. Ramaswamy X. Zhang H. M. Burt K. M. Wasan 1997 Human plasma distribution of free paclitaxel and paclitaxel associated with diblock copolymers J. Pharm. Sci. 86 460 464
33. J. A. [tmp] MacKay D. F. Deen F. C. Szoka Jr 2005 Distribution in brain of liposomes after convection enhanced delivery; modulation by particle charge, particle diameter, and presence of steric coating Brain Res. 1035 139 153
34. T. L. Andresen S. S. Jensen K. Jorgensen 2005 Advanced strategies in liposomal cancer therapy: problems and prospects of active and tumor specific disease Prog. Lipid Res. 44 68 97
35. V. S. Trubetskoy V. P. Torchilin 1995 Use of polyethylene-lipid conjugates as long-circulating carriers for delivery of therapeutic and diagnostic agents Adv. Drug Deliv. Rev. 16 311 320