Molecular characterization of human and rat organic anion transporter OATP-D

American Journal of Physiology - Renal Physiology

Volumn 285, Issue 6 54-6, 2003, Pages

  Adachi, Hisanobu ^a   Suzuki, Takehiro ^a   Abe, Michiaki ^a   Asano, Naoki ^a   Mizutamari, Hiroya ^a   Tanemoto, Masayuki ^a   Nishio, Toshiyuki ^a   Onogawa, Tohru ^a   Toyohara, Takafumi ^a   Kasai, Satoshi ^a   Satoh, Fumitoshi ^a   Suzuki, Masanori ^a   Tokui, Taro ^b   Unno, Michiaki ^a   Shimosegawa, Tooru ^a   Matsuno, Seiki ^a   Ito, Sadayoshi ^a   Abe, Takaaki ^a,c  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b DAIICHI SANKYO CO   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Eicosanoid; Prostaglandin transporter

Indexed keywords

ADENOSINE TRIPHOSPHATE; ICOSANOID; MESSENGER RNA; ORGANIC ANION TRANSPORTER; PROSTAGLANDIN; PROSTAGLANDIN E2;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DNA ISOLATION; HUMAN; HUMAN CELL; HYPOPHYSIS FUNCTION; IMMUNOHISTOCHEMISTRY; LIPID BILAYER; MOLECULAR LIBRARY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENETIC TREE CONSTRUCTION METHOD; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RAT; SEQUENCE HOMOLOGY;

EID: 0242497239     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00402.2002     Document Type: Article

References (50)

1. Abe T, Kakyo M, Sakagami H, Tokui T, Nishio T, Tanemoto M, Nomura H, Hebert SC, Matsuno S, Kondo H, and Yawo H. Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2. J Biol Chem 273: 22395-22401, 1998.
2. Abe T, Kakyo M, Tokui T, Nakagomi R, Nishio T, Nakai D, Nomura H, Unno M, Suzuki M, Naitoh T, Matsuno S, Kondo H, and Yawo H. Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1. J Biol Chem 274: 17159-17163, 1999.
3. 2+ signal transduction. J Biol Chem 267: 13361-13368, 1992.
4. Abe T, Suzuki T, Unno M, Tokui T, and Ito S. Thyroid hormone transporters: recent advances. Trends Endocrinol Metab 13: 215-220, 2002.
5. Abe T, Unno M, Onogawa T, Tokui T, Kondo TN, Nakagomi R, Adachi H, Fujiwara K, Okabe M, Suzuki T, Nunoki K, Sato E, Kakyo M, Nishio Y, Sugita J, Asano N, Tanemoto M, Seki M, Date F, Ono K, Nagura H, Ito S, and Matsuno S. LST-2, a human liver-specific organ anion transporter, determines methotrexate sensitivity in gastrointestinal cancers. Gastroenterology 120: 1689-1699, 2001.
6. Anderson MW and Eling TE. Prostaglandin removal and metabolism by isolated perfused rat lung. Prostaglandins 11: 645-677, 1976.
7. 2, prostacyclin and 6-keto-PGF1 alpha. Prostaglandins 21: 133-142, 1981.
8. Breyer MD and Breyer RM. Prostaglandin E receptors and the kidney. Am J Physiol Renal Physiol 279: F12-F23, 2000.
9. 4 receptor. Am J Physiol Renal Fluid Electrolyte Physiol 270: F485-F493, 1996.
10. Campbell WB and Halshka PV. Lipid-derived autacoids: eicosanoids, and platelet-activating factor. In: Goodman and Gilman's The Pharmacological Basis of Therapeutics (9th ed.), edited by Hardman JG. New York: McGraw-Hill, 1996.
11. 2 transport across the plasma membrane of HeLa cells and Xenopus oocytes expressing the prostaglandin transporter "PGT." J Biol Chem 273: 6689-6697, 1998.
12. 2α in rats. J Pharmacol Exp Ther 262: 1110-1120, 1992.
13. Ferreira SH and Vane JR. Prostaglandins: their disappearance from and release into the circulation. Nature 216: 868-873, 1967.
14. Gerashchenko D, Beuckmann CT, Kanaoka Y, Eguchi N, Gordon WC, Urade Y, Bazan NG, and Hayaishi O. Dominant expression of rat prostanoid DP receptor mRNA in leptomeninges, inner segments of photoreceptor cells, iris epithelium, and ciliary processes. J Neurochem 71: 937-945, 1998.
15. 1 receptor. J Clin Invest 102: 194-201, 1998.
16. Hakes DJ and Berezney R. Molecular cloning of matrinF/G: a DNA binding protein of the nuclear matrix that contains putative zinc finger motifs. Proc Natl Acad Sci USA 88: 6186-6190, 1991.
17. Halushka PV, Mais DE, Mayeux PR, and Morinelli TA. Thromboxane, prostaglandin, and leukotriene receptors. Annu Rev Pharmacol Toxicol 29: 213-239, 1989.
18. Hamberg M. Biosynthesis of prostaglandin El by human seminal vesicles. Lipids 11: 249-250, 1975.
19. 2. FASEB J 5: 2572-2581, 1991.
20. 2. Proc Natl Acad Sci USA 96: 10501-10506, 1999.
21. 3) in the nonischemic and ischemic pig heart. Circ Res 81: 765-773, 1997.
22. Ito S, Carretero OA, Abe K, Beierwaltes WH, and Yoshinaga K. Effect of prostanoids on renin release from rabbit afferent arterioles with and without macula densa. Kidney Int 35: 1138-1144, 1989.
23. +-independent organic anion transporter. Proc Natl Acad Sci USA 91: 133-137, 1994.
24. Kakyo M, Sakagami H, Nishio T, Nakai D, Nakagomi R, Tokui T, Naitoh T, Matsuno S, Abe T, and Yawo H. Immunohistochemical distribution, and functional characterization of an organic anion transporting polypeptide 2 (oatp2). FEBS Lett 445: 343-346, 1999.
25. Kakyo M, Unno M, Tokui T, Nakagomi R, Nishio T, Iwasashi H, Nakai D, Seki M, Suzuki M, Naito T, Matuno S, Yawo H, and Abe T. Molecular characterization, and functional regulation of a novel rat liver-specific organic anion transporter rlst-1. Gastroenterology 117: 770-775, 1999.
26. Kanai N, Lu R, Satriano JA, Bao Y, Wolkoff AW, and Schuster VL. Identification and characterization of a prostaglandin transporter. Science 268: 866-869, 1995.
27. Kemp BE and Pearson RB. Protein kinase recognition sequence motifs. Trends Biochem Sci 15: 342-346, 1990.
28. Kennelly PJ and Krebs EG. Consensus sequences as substrate specificity determinants for protein kinases, and protein phosphatases. J Biol Chem 266: 15555-15558, 1991.
29. Kullak-Ublick GA, Hagenbuch B, Stieger B, Schteingart CD, Hofmann AF, Wolkoff AW, and Meier PJ. Molecular, and functional characterization of an organic anion transporting polypeptide cloned from human liver. Gastroenterology 109: 1274-1282, 1995.
30. Kyte J and Doolittle RF. A simple method for displaying the hydropathic character of a protein. J Mol Biol 157: 105-132, 1982.
31. Li L, Meier PJ, and Ballatori N. Oatp2 mediates bidirectional organic solute transport: a role for intracellular glutathione. Mol Pharmacol 58: 335-340, 2000.
32. Lim H, Paria BC, Das SK, Dinchuk JE, Langenbach R, Trzaskos JM, and Dey SK. Multiple female reproductive failures in cyclooxygenase 2-deficient mice. Cell 91: 197-208, 1997.
33. Lu R, Kanai N, and Schuster V. Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA (hPGT). J Clin Invest 98: 1142-1149, 1996.
34. Masuda S, Ibaramoto K, Takeuchi A, Saito H, Hashimoto Y, and Inui KI. Cloning, and functional characterization of a new multispecific organic anion transporter, OAT-K2, in rat kidney. Mol Pharmacol 55: 743-752, 1999.
35. 4 receptors in human nonpregnant endometrium across the menstrual cycle. J Clin Endocrinol Metab 86: 4453-4459, 2001.
36. Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, and Ohara O. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res 5: 355-364, 1998.
37. 2 in rat brain, spinal cord, and pituitary: basal level and regional distribution. Life Sci 31: 2093-2103, 1982.
38. Narumiya S, Sugimoto Y, and Ushikubi F. Prostanoid receptors: structures, properties, and functions. Physiol Rev 79: 1193-1226, 1999.
39. 4, and taurocholate. Biochem Biophys Res Commun 275: 946-954, 2000.
40. Noé B, Hagenbuch B, Stieger B, and Meier PJ. Isolation of a multispecific organic anion, and cardiac glycoside transporter from rat brain. Proc Natl Acad Sci USA 94: 10346-10350, 1997.
41. Oida H, Hirata M, Sugimoto Y, Ushikubi F, Ohishi H, Mizuno N, Ichikawa A, and Narumiya S. Expression of messenger RNA for the prostaglandin D receptor in the leptomeninges of the mouse brain. FEBS Lett 417: 53-56, 1997.
42. Page RD. TreeView: an application to display phylogenetic trees on personal computers. Comput Appl Biosci 12: 357-358, 1996.
43. Saito H, Masuda S, and Inui K. Cloning, and functional characterization of a novel rat organic anion transporter mediating basolateral uptake of methotrexate in the kidney. J Biol Chem 271: 20719-20725, 1996.
44. Samuelsson B, Goldyne M, Grandström E, Hamberg M, Hammerström S, and Malmsten C. Prostaglandins and thromboxanes. Annu Rev Biochem 47: 997-1029, 1978.
45. Subbaramaiah K and Dannenberg AJ. Cyclooxygenase 2: a molecular target for cancer prevention, and treatment. Trends Pharmacol Sci 24: 96-102, 2003.
46. Tamai I, Nezu J, Uchino H, Sai Y, Oku A, Shimane M, and Tsuji A. Molecular identification, and characterization of novel members of the human organic anion transporter (OATP) family. Biochem Biophys Res Commun 273: 251-260, 2000.
47. 4 receptors. Circ Res 86: 663-670, 2000.
48. Thompson JD, Higgins DG, and Gibson TJ. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties, and weight matrix choice. Nucleic Acids Res 22: 4673-4680, 1994.
49. Topper JN, Cai J, Stavrakis G, Anderson KR, Woolf EA, Sampson BA, Schoen FJ, Falb D, and Gimbrone MA Jr. Human prostaglandin transporter gene (hPGT) is regulated by fluid mechanical stimuli in cultured endothelial cells, and expressed in vascular endothelium in vivo. Circulation 98: 2396-2403, 1998.
50. Wolfe LS and Coceani F. The role of prostaglandins in the central nervous system. Annu Rev Physiol 41: 669-684, 1979.