A new powder design method to improve inhalation efficiency of pranlukast hydrate dry powder aerosols by surface modification with hydroxypropylmethylcellulose phthalate nanospheres

Pharmaceutical Research

Volumn 15, Issue 11, 1998, Pages 1748-1752

  Kawashima, Yoshiaki ^a   Serigano, Takanori ^a   Hino, Tomoaki ^a,b   Yamamoto, Hiromitsu ^a   Takeuchi, Hirofumi ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Dry powder inhalation; Hydroxypropylmethylcellulose phthalate nanosphere; Inhalation efficiency in vitro; Powder design; Pranlukast hydrate; Surface modification

Indexed keywords

DRUG CARRIER; HYDROXYPROPYLMETHYLCELLULOSE PHTHALATE; LACTOSE; NANOPARTICLE; PRANLUKAST;

AEROSOL; AQUEOUS SOLUTION; ARTICLE; CHEMICAL MODIFICATION; DIFFUSION; DISPERSION; DISSOLUTION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG FORMULATION; DRY POWDER; EMULSION; FREEZE DRYING; HYDROPHILICITY; INHALATIONAL DRUG ADMINISTRATION; POWDER INHALER; PRIORITY JOURNAL;

ADMINISTRATION, INHALATION; AEROSOLS; ANTI-ASTHMATIC AGENTS; CHROMONES; CULTURE MEDIA; LEUKOTRIENE ANTAGONISTS; LINEAR MODELS; METHYLCELLULOSE; MICROSPHERES; POWDERS; SURFACE PROPERTIES; WATER;

EID: 0031725355     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011916930655     Document Type: Article

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