Spray-dried poly(D,L-lactide) microspheres containing carboplatin for veterinary use: In vitro and in vivo studies

AAPS PharmSciTech

Volumn 6, Issue 1, 2005, Pages

  Gavini, Elisabetla ^a   Manunta, Lucia ^a   Giua, Stefano ^a   Achenza, Giannina ^b   Giunchedi, Paolo ^a  

^a UNIVERSITY OF SASSARI   (Italy)

^b ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLA SARDEGNA   (Italy)

Author keywords

Carboplatin; Companion animals; Local chemotherapy; Microspheres; Poly(D,L lactide); Spray drying

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; MICROSPHERE; POLYGLACTIN; POLYMER; VETERINARY DRUG;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; AREA UNDER THE CURVE; ARTICLE; BIODEGRADABILITY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DOSE REGIMEN; DRUG RELEASE; DRUG TISSUE LEVEL; EMULSION; IN VITRO STUDY; IN VIVO STUDY; MALE; METASTASIS; NONHUMAN; PARTICLE SIZE; RAT; SKIN; SPRAY DRYING; SUSPENSION; TUMOR RECURRENCE; WEIGHT;

ANIMALS; CARBOPLATIN; MALE; MICROSPHERES; POLYESTERS; RATS; RATS, WISTAR; SKIN NEOPLASMS; VETERINARY DRUGS;

EID: 27844562815     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt060117     Document Type: Article

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