Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels

Inflammatory Bowel Diseases

Volumn 13, Issue 6, 2007, Pages 710-720

  Blokzijl, Hans ^a   Vander Borght, Sara ^b   Bok, Lisette I H ^a   Libbrecht, Louis ^b   Geuken, Mariska ^a   Van Den Heuvel, Fiona A J ^a   Dijkstra, Gerard ^a   Roskams, Tania A D ^b   Moshage, Han ^a   Jansen, Peter L M ^c   Faber, Klaas Nico ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Inflammation; Intestinal epithelium; P glycoprotein multidrug resistance 1; Pregnane X receptor

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID DERIVATIVE; CYTOCHROME P450 3A4; GAMMA INTERFERON; GLYCOPROTEIN P; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MESALAZINE; MESSENGER RNA; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 1; PREGNANE X RECEPTOR; SALAZOSULFAPYRIDINE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CLINICAL ARTICLE; COLLAGENOUS COLITIS; CONTROLLED STUDY; CROHN DISEASE; DIVERTICULITIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; ILEUM; IMMUNOHISTOCHEMISTRY; INTESTINE BIOPSY; INTESTINE EPITHELIUM; INTESTINE MUCOSA; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ULCERATIVE COLITIS; WESTERN BLOTTING;

ADOLESCENT; ADULT; AGED; BIOLOGICAL MARKERS; BIOPSY; BLOTTING, WESTERN; EPITHELIUM; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; MALE; MIDDLE AGED; P-GLYCOPROTEIN; RECEPTORS, STEROID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 34247616480     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.20088     Document Type: Article

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