Role of acetylcholine and muscarinic receptors in serotonin-induced bronchoconstriction in the mouse

Journal of Molecular Neuroscience

Volumn 30, Issue 1-2, 2006, Pages 67-68

  Kummer, Wolfgang ^a   Wiegand, Silke ^a   Akinci, Sibel ^a   Schinkel, Alfred H ^b   Wess, Jürgen ^c   Koepsell, Hermann ^d   Haberberger, Rainer Viktor ^a   Lips, Katrin Susanne ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; CHOLINERGIC RECEPTOR; CORTICOSTERONE; MUSCARINE; MUSCARINIC RECEPTOR; SEROTONIN;

ANIMAL MODEL; ANIMAL TISSUE; BRONCHOSPASM; CONFERENCE PAPER; CONTROLLED STUDY; LUNG SLICE; MORPHOMETRICS; MOUSE; MOUSE STRAIN; NONHUMAN; WILD TYPE;

ACETYLCHOLINE; ANIMALS; BRONCHOCONSTRICTION; CORTICOSTERONE; MICE; MICE, KNOCKOUT; RECEPTORS, MUSCARINIC; SEROTONIN;

EID: 33845920612     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1385/JMN:30:1:67     Document Type: Conference Paper

References (6)

1. Lips K. S., Volk C., Schmitt B. M., Pfeil U., Arndt P., Miska D., et al. (2005) Polyspecific cation transporters mediate luminal release of acetylcholine from bronchial epithelium. Am. J. Respir. Cell. Mol. Biol. 33, 79-88.
2. Moffatt J. D., Cocks T. M., and Page C. P. (2003) Role of the epithelium and acetylcholine in mediating the contraction to 5-hydroxytryptamine in the mouse isolated trachea. Br. J. Pharmacol. 141, 1159-1166.
3. Pfeil U., Lips K. S., Eberling L., Grau V., Haberberger R. V., and Kummer W. (2003) Expression of the high-affinity choline transporter, CHT1, in the rat trachea. Am. J. Respir. Cell. Mol. Biol. 28, 473-477.
4. Proskocil B. J., Sekhon H. S., Jia Y., Savchenko V., Blakely R. D., Lindstrom J., and Spindel E. R. (2004) Acetylcholine is an autocrine or paracrine hormone synthesized and secreted by airway bronchial epithelial cells. Endocrinology 145, 2498-2506.
5. Reinheimer T., Bernedo P., Klapproth H., Oelert H., Zeiske B., Racke K., and Wessler I. (1996) Acetylcholine in isolated airways of rat, guinea pig, and human: species: differences in role of airway mucosa. Am. J. Physiol. 270, L722-L728.
6. Struckmann N., Schwering S., Wiegand S., Gschnell A., Yamada M., Kummer W., et al. (2003) Role of muscarinic receptor subtypes in the constriction of peripheral airways: studies on receptor-deficient mice. Mol. Pharmacol. 64, 1444-1451.