Hypoxia-inducible factor as a therapeutic target for cardioprotection

Pharmacology and Therapeutics

Volumn 136, Issue 1, 2012, Pages 69-81

  Ong, Sang Ging ^a   Hausenloy, Derek J ^a  

^a UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

Author keywords

Cardioprotection; Heart; Hypoxia inducible factor; Prolyl hydroxylase domain containing enzyme; von Hippel Lindau protein

Indexed keywords

CARDIAC AGENT; COBALT CHLORIDE; DESFERROXAMINE; DIMETHYLOXALYLGLYCINE; ENZYME; ERYTHROPOIETIN; ETHYL 3,4 DIHYDROXYBENZOATE; FG 2216; FG 4562; GSK 360A; HEME OXYGENASE 1; HYDROXYBENZOIC ACID DERIVATIVE; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; IRON CHELATING AGENT; LIM DOMAIN CONTAINING PROTEIN 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROLYL HYDROXYLASE DOMAIN CONTAINING ENZYME; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SIRTUIN; TM 6008; TM 6089; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN;

DRUG TARGETING; ENZYME ACTIVITY; ENZYME REGULATION; GENE EXPRESSION; GENETICS; HEART MUSCLE ISCHEMIA; HEART PROTECTION; ISCHEMIC PRECONDITIONING; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; REVIEW;

ADIPONECTIN; ANIMALS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENETIC THERAPY; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; LIM DOMAIN PROTEINS; MICRORNAS; MITOCHONDRIA; MYOCARDIAL REPERFUSION INJURY; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTO-ONCOGENE PROTEINS C-AKT; SIRTUINS; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 84865610131     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2012.07.005     Document Type: Review

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