메뉴 건너뛰기




Volumn 31, Issue 9, 2010, Pages 1085-1094

Hypoxia inducible factor 1 (HIF-1) and cardioprotection

Author keywords

cardioprotection; hypoxia inducible factor; ischemia reperfusion; myocardial infarction; preconditioning; signal transduction

Indexed keywords

CARDIOVASCULAR AGENT; CARVEDILOL; CICLOPIROXOLAMINE; COBALT CHLORIDE; DEFEROXAMINE; DIMETHYLOXALYLGLYCINE; ENZYME INHIBITOR; ERYTHROPOIETIN; GLYCINE DERIVATIVE; GSK 360A; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INHALATION ANESTHETIC AGENT; ISOFLURANE; MICRORNA; MICRORNA 199A; NITRIC OXIDE SYNTHASE; PROLYL HYDROXYLASE INHIBITOR; RAPAMYCIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 77956388934     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.132     Document Type: Review
Times cited : (141)

References (72)
  • 1
    • 0026075610 scopus 로고
    • Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene
    • Semenza GL, Nejfelt MK, Chi SM, Antonarakis SE. Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene. Proc Natl Acad Sci USA 1991; 88: 5680-5684.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5680-5684
    • Semenza, G.L.1    Nejfelt, M.K.2    Chi, S.M.3    Antonarakis, S.E.4
  • 2
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 1995; 92: 5510-5514.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 3
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxiainducible factor 1
    • Wang GL, Semenza GL. Purification and characterization of hypoxiainducible factor 1. J Biol Chem 1995; 270: 1230-1237
    • (1995) J Biol Chem , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 4
    • 0029788974 scopus 로고    scopus 로고
    • Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alpha
    • Li H, Ko HP, Whitlock JP. Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alpha. J Biol Chem 1996; 271: 21262-21267
    • (1996) J Biol Chem , vol.271 , pp. 21262-21267
    • Li, H.1    Ko, H.P.2    Whitlock, J.P.3
  • 5
    • 0035917808 scopus 로고    scopus 로고
    • Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
    • Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, et al. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 2001; 292: 468-472
    • (2001) Science , vol.292 , pp. 468-472
    • Jaakkola, P.1    Mole, D.R.2    Tian, Y.M.3    Wilson, M.I.4    Gielbert, J.5    Gaskell, S.J.6
  • 6
    • 0035917313 scopus 로고    scopus 로고
    • HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: Implications for O2 sensing
    • Ivan M, Kondo K, Yang H, Kim W, Valiando J, Ohh M, et al. HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 2001; 292: 464-468
    • (2001) Science , vol.292 , pp. 464-468
    • Ivan, M.1    Kondo, K.2    Yang, H.3    Kim, W.4    Valiando, J.5    Ohh, M.6
  • 7
    • 0030961006 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redoxinduced changes
    • Salceda S, Caro J. Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redoxinduced changes. J Biol Chem 1997; 272: 22642-22647
    • (1997) J Biol Chem , vol.272 , pp. 22642-22647
    • Salceda, S.1    Caro, J.2
  • 8
    • 18744375998 scopus 로고    scopus 로고
    • Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation
    • Jeong JW, Bae MK, Ahn MY, Kim SH, Sohn TK, Bae MH, et al. Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation. Cell 2002; 111: 709-720
    • (2002) Cell , vol.111 , pp. 709-720
    • Jeong, J.W.1    Bae, M.K.2    Ahn, M.Y.3    Kim, S.H.4    Sohn, T.K.5    Bae, M.H.6
  • 9
    • 0034663894 scopus 로고    scopus 로고
    • Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein
    • Tanimoto K, Makino Y, Pereira T, Poellinger L. Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein. EMBO J 2000; 19: 4298-4309
    • (2000) EMBO J , vol.19 , pp. 4298-4309
    • Tanimoto, K.1    Makino, Y.2    Pereira, T.3    Poellinger, L.4
  • 10
    • 0034682783 scopus 로고    scopus 로고
    • Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
    • Cockman ME, Masson N, Mole DR, Jaakkola P, Chang GW, Clifford SC, et al. Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein. J Biol Chem 2000; 275: 25733-25741
    • (2000) J Biol Chem , vol.275 , pp. 25733-25741
    • Cockman, M.E.1    Masson, N.2    Mole, D.R.3    Jaakkola, P.4    Chang, G.W.5    Clifford, S.C.6
  • 11
    • 0037097861 scopus 로고    scopus 로고
    • FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
    • Lando D, Peet DJ, Gorman JJ, Whelan DA, Whitelaw ML, Bruick RK. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev 2002; 16: 1466-1471
    • (2002) Genes Dev , vol.16 , pp. 1466-1471
    • Lando, D.1    Peet, D.J.2    Gorman, J.J.3    Whelan, D.A.4    Whitelaw, M.L.5    Bruick, R.K.6
  • 12
    • 0031000736 scopus 로고    scopus 로고
    • A novel bHLH-PAS factor with close sequence similarity to hypoxiainducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development
    • Ema M, Taya S, Yokotani N, Sogawa K, Matsuda Y, Fujii-Kuriyama Y. A novel bHLH-PAS factor with close sequence similarity to hypoxiainducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development. Proc Natl Acad Sci USA 1997; 94: 4273-4278
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4273-4278
    • Ema, M.1    Taya, S.2    Yokotani, N.3    Sogawa, K.4    Matsuda, Y.5    Fujii-Kuriyama, Y.6
  • 13
    • 11244315697 scopus 로고    scopus 로고
    • Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
    • Manalo DJ, Rowan A, Lavoie T, Natarajan L, Kelly BD, Ye SQ, et al. Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. Blood 2005; 105: 659-669
    • (2005) Blood , vol.105 , pp. 659-669
    • Manalo, D.J.1    Rowan, A.2    Lavoie, T.3    Natarajan, L.4    Kelly, B.D.5    Ye, S.Q.6
  • 16
    • 0028843411 scopus 로고
    • Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents
    • Gleadle JM, Ebert BL, Firth JD, Ratcliffe PJ. Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents. Am J Physiol 1995; 268: C1362-C1368.
    • (1995) Am J Physiol , vol.268
    • Gleadle, J.M.1    Ebert, B.L.2    Firth, J.D.3    Ratcliffe, P.J.4
  • 17
    • 9344262366 scopus 로고    scopus 로고
    • Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1alpha and AP-1 and iNOS signaling
    • Xi L, Taher M, Yin C, Salloum F, Kukreja RC. Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1alpha and AP-1 and iNOS signaling. Am J Physiol Heart Circ Physiol 2004; 287: H2369-75.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Xi, L.1    Taher, M.2    Yin, C.3    Salloum, F.4    Kukreja, R.C.5
  • 18
    • 0037844847 scopus 로고    scopus 로고
    • Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha
    • Yuan Y, Hilliard G, Ferguson T, Millhorn DE. Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha. J Biol Chem 2003; 278: 15911-15916
    • (2003) J Biol Chem , vol.278 , pp. 15911-15916
    • Yuan, Y.1    Hilliard, G.2    Ferguson, T.3    Millhorn, D.E.4
  • 20
    • 0037073695 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms
    • Page EL, Robitaille GA, Pouyssegur J, Richard DE. Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms. J Biol Chem 2002; 277: 48403-48409
    • (2002) J Biol Chem , vol.277 , pp. 48403-48409
    • Page, E.L.1    Robitaille, G.A.2    Pouyssegur, J.3    Richard, D.E.4
  • 21
    • 0035816732 scopus 로고    scopus 로고
    • Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase
    • Gorlach A, Diebold I, Schini-Kerth VB, Berchner-Pfannschmidt U, Roth U, Brandes RP, et al. Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase. Circ Res 2001; 89: 47-54.
    • (2001) Circ Res , vol.89 , pp. 47-54
    • Gorlach, A.1    Diebold, I.2    Schini-Kerth, V.B.3    Berchner-Pfannschmidt, U.4    Roth, U.5    Brandes, R.P.6
  • 22
    • 1342346637 scopus 로고    scopus 로고
    • O2-regulated gene expression: Transcriptional control of cardiorespiratory physiology by HIF-1
    • Semenza GL. O2-regulated gene expression: transcriptional control of cardiorespiratory physiology by HIF-1. J Appl Physiol 2004; 96: 1173-1177
    • (2004) J Appl Physiol , vol.96 , pp. 1173-1177
    • Semenza, G.L.1
  • 23
    • 0038163900 scopus 로고    scopus 로고
    • Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury
    • Cai Z, Manalo DJ, Wei G, Rodriguez ER, Fox-Talbot K, Lu H, et al. Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury. Circulation 2003; 108: 79-85.
    • (2003) Circulation , vol.108 , pp. 79-85
    • Cai, Z.1    Manalo, D.J.2    Wei, G.3    Rodriguez, E.R.4    Fox-Talbot, K.5    Lu, H.6
  • 24
    • 36849039478 scopus 로고    scopus 로고
    • Keeping the engine primed: HIF factors as key regulators of cardiac metabolism and angiogenesis during ischemia
    • Shohet RV, Garcia JA. Keeping the engine primed: HIF factors as key regulators of cardiac metabolism and angiogenesis during ischemia. J Mol Med 2007; 85: 1309-1315
    • (2007) J Mol Med , vol.85 , pp. 1309-1315
    • Shohet, R.V.1    Garcia, J.A.2
  • 25
    • 65349099945 scopus 로고    scopus 로고
    • Hypoxiainducible factor 1 and related gene products in anaesthetic-induced preconditioning
    • Hieber S, Huhn R, Hollmann MW, Weber NC, Preckel B. Hypoxiainducible factor 1 and related gene products in anaesthetic-induced preconditioning. Eur J Anaesthesiol 2009; 26: 201-206
    • (2009) Eur J Anaesthesiol , vol.26 , pp. 201-206
    • Hieber, S.1    Huhn, R.2    Hollmann, M.W.3    Weber, N.C.4    Preckel, B.5
  • 26
    • 40949088023 scopus 로고    scopus 로고
    • Role of hypoxia-inducible factor in cell survival during myocardial ischemia-reperfusion
    • Loor G, Schumacker PT. Role of hypoxia-inducible factor in cell survival during myocardial ischemia-reperfusion. Cell Death Differ 2008; 15: 686-690
    • (2008) Cell Death Differ , vol.15 , pp. 686-690
    • Loor, G.1    Schumacker, P.T.2
  • 28
    • 39149108824 scopus 로고    scopus 로고
    • Prevention of HIF-1 activation and iNOS gene targeting by low-dose cadmium results in loss of myocardial hypoxic preconditioning in the rat
    • Belaidi E, Beguin PC, Levy P, Ribuot C, Godin-Ribuot D. Prevention of HIF-1 activation and iNOS gene targeting by low-dose cadmium results in loss of myocardial hypoxic preconditioning in the rat. Am J Physiol Heart Circ Physiol 2008; 294: H901-H908.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Belaidi, E.1    Beguin, P.C.2    Levy, P.3    Ribuot, C.4    Godin-Ribuot, D.5
  • 29
    • 15244348096 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase contributes to intermittent hypoxia against ischemia/reperfusion injury
    • Ding HL, Zhu HF, Dong JW, Zhu WZ, Yang WW, Yang HT, et al. Inducible nitric oxide synthase contributes to intermittent hypoxia against ischemia/reperfusion injury. Acta Pharmacol Sin 2005; 26: 315-322
    • (2005) Acta Pharmacol Sin , vol.26 , pp. 315-322
    • Ding, H.L.1    Zhu, H.F.2    Dong, J.W.3    Zhu, W.Z.4    Yang, W.W.5    Yang, H.T.6
  • 31
    • 0033976342 scopus 로고    scopus 로고
    • Hypoxic regulation of inducible nitric oxide synthase via hypoxia inducible factor-1 in cardiac myocytes
    • Jung F, Palmer LA, Zhou N, Johns RA. Hypoxic regulation of inducible nitric oxide synthase via hypoxia inducible factor-1 in cardiac myocytes. Circ Res 2000; 86: 319-325
    • (2000) Circ Res , vol.86 , pp. 319-325
    • Jung, F.1    Palmer, L.A.2    Zhou, N.3    Johns, R.A.4
  • 33
    • 38849182762 scopus 로고    scopus 로고
    • Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1 alpha
    • Cai Z, Zhong H, Bosch-Marce M, Fox-Talbot K, Wang L, Wei C, et al. Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1 alpha. Cardiovasc Res 2008; 77: 463-470
    • (2008) Cardiovasc Res , vol.77 , pp. 463-470
    • Cai, Z.1    Zhong, H.2    Bosch-Marce, M.3    Fox-Talbot, K.4    Wang, L.5    Wei, C.6
  • 34
    • 47649128513 scopus 로고    scopus 로고
    • Hypoxiainducible factor-1 is central to cardioprotection: A new paradigm for ischemic preconditioning
    • Eckle T, Kohler D, Lehmann R, El Kasmi K, Eltzschig HK. Hypoxiainducible factor-1 is central to cardioprotection: a new paradigm for ischemic preconditioning. Circulation 2008; 118: 166-175
    • (2008) Circulation , vol.118 , pp. 166-175
    • Eckle, T.1    Kohler, D.2    Lehmann, R.3    El Kasmi, K.4    Eltzschig, H.K.5
  • 35
    • 0033081837 scopus 로고    scopus 로고
    • Renal ischemia/reperfusion remotely improves myocardial energy metabolism during myocardial ischemia via adenosine receptors in rabbits: Effects of "remote preconditioning"
    • Takaoka A, Nakae I, Mitsunami K, Yabe T, Morikawa S, Inubushi T, et al. Renal ischemia/reperfusion remotely improves myocardial energy metabolism during myocardial ischemia via adenosine receptors in rabbits: effects of "remote preconditioning". J Am Coll Cardiol 1999; 33: 556-564
    • (1999) J Am Coll Cardiol , vol.33 , pp. 556-564
    • Takaoka, A.1    Nakae, I.2    Mitsunami, K.3    Yabe, T.4    Morikawa, S.5    Inubushi, T.6
  • 36
    • 42149153182 scopus 로고    scopus 로고
    • Remote renal preconditioning-induced cardioprotection: A key role of hypoxia inducible factorprolyl 4-hydroxylases
    • Kant R, Diwan V, Jaggi AS, Singh N, Singh D. Remote renal preconditioning-induced cardioprotection: a key role of hypoxia inducible factorprolyl 4-hydroxylases. Mol Cell Biochem 2008; 312: 25-31.
    • (2008) Mol Cell Biochem , vol.312 , pp. 25-31
    • Kant, R.1    Diwan, V.2    Jaggi, A.S.3    Singh, N.4    Singh, D.5
  • 37
    • 0035853423 scopus 로고    scopus 로고
    • Ischemic preconditioning upregulates vascular endothelial growth factor mRNA expression and neovascularization via nuclear translocation of protein kinase C epsilon in the rat ischemic myocardium
    • Kawata H, Yoshida K, Kawamoto A, Kurioka H, Takase E, Sasaki Y, et al. Ischemic preconditioning upregulates vascular endothelial growth factor mRNA expression and neovascularization via nuclear translocation of protein kinase C epsilon in the rat ischemic myocardium. Circ Res 2001; 88: 696-704.
    • (2001) Circ Res , vol.88 , pp. 696-704
    • Kawata, H.1    Yoshida, K.2    Kawamoto, A.3    Kurioka, H.4    Takase, E.5    Sasaki, Y.6
  • 38
    • 54949132480 scopus 로고    scopus 로고
    • Human adaptation to ischemia by preconditioning or unstable angina: Involvement of nuclear factor kappa B, but not hypoxia-inducible factor 1 alpha in the heart
    • Czibik G, Wu Z, Berne GP, Tarkka M, Vaage J, Laurikka J, et al. Human adaptation to ischemia by preconditioning or unstable angina: involvement of nuclear factor kappa B, but not hypoxia-inducible factor 1 alpha in the heart. Eur J Cardiothorac Surg 2008; 34: 976-984
    • (2008) Eur J Cardiothorac Surg , vol.34 , pp. 976-984
    • Czibik, G.1    Wu, Z.2    Berne, G.P.3    Tarkka, M.4    Vaage, J.5    Laurikka, J.6
  • 39
    • 0037623908 scopus 로고    scopus 로고
    • Inhibition of myocardial injury by ischemic postconditioning during reperfusion: Comparison with ischemic preconditioning
    • Zhao ZQ, Corvera JS, Halkos ME, Kerendi F, Wang NP, Guyton RA, et al. Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. Am J Physiol Heart Circ Physiol 2003; 285: H579-88.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Zhao, Z.Q.1    Corvera, J.S.2    Halkos, M.E.3    Kerendi, F.4    Wang, N.P.5    Guyton, R.A.6
  • 40
    • 54449094375 scopus 로고    scopus 로고
    • Loss of myocardial ischemic postconditioning in adenosine A1 and bradykinin B2 receptors gene knockout mice
    • Xi L, Das A, Zhao ZQ, Merino VF, Bader M, Kukreja RC. Loss of myocardial ischemic postconditioning in adenosine A1 and bradykinin B2 receptors gene knockout mice. Circulation 2008; 118: S32-7.
    • (2008) Circulation , vol.118
    • Xi, L.1    Das, A.2    Zhao, Z.Q.3    Merino, V.F.4    Bader, M.5    Kukreja, R.C.6
  • 41
    • 72449173802 scopus 로고    scopus 로고
    • Attenuation of myocardial injury by postconditioning: Role of hypoxia inducible factor-1alpha
    • Zhao HX, Wang XL, Wang YH, Wu Y, Li XY, Lv XP, et al. Attenuation of myocardial injury by postconditioning: role of hypoxia inducible factor-1alpha. Basic Res Cardiol 2010;105: 109-118
    • (2010) Basic Res Cardiol , vol.105 , pp. 109-118
    • Zhao, H.X.1    Wang, X.L.2    Wang, Y.H.3    Wu, Y.4    Li, X.Y.5    Lv, X.P.6
  • 42
    • 73349088449 scopus 로고    scopus 로고
    • Hyperlipidemia does not prevent the cardioprotection by postconditioning against myocardial ischemia/reperfusion injury and the involvement of hypoxia inducible factor-1alpha upregulation
    • Zhao H, Wang Y, Wu Y, Li X, Yang G, Ma X, et al. Hyperlipidemia does not prevent the cardioprotection by postconditioning against myocardial ischemia/reperfusion injury and the involvement of hypoxia inducible factor-1alpha upregulation. Acta Biochim Biophys Sin 2009; 41: 745-753
    • (2009) Acta Biochim Biophys Sin , vol.41 , pp. 745-753
    • Zhao, H.1    Wang, Y.2    Wu, Y.3    Li, X.4    Yang, G.5    Ma, X.6
  • 43
    • 33646842687 scopus 로고    scopus 로고
    • Cobalt chloride pretreatment attenuates myocardial apoptosis after hypothermic circulatory arrest
    • Thoracic Surgery Directors Association Award
    • Kerendi F, Kirshbom PM, Halkos ME, Wang NP, Kin H, Jiang R, et al. Thoracic Surgery Directors Association Award. Cobalt chloride pretreatment attenuates myocardial apoptosis after hypothermic circulatory arrest. Ann Thorac Surg 2006; 81: 2055-2062
    • (2006) Ann Thorac Surg , vol.81 , pp. 2055-2062
    • Kerendi, F.1    Kirshbom, P.M.2    Halkos, M.E.3    Wang, N.P.4    Kin, H.5    Jiang, R.6
  • 44
    • 33745897224 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases trigger isoflurane preconditioning concomitant with upregulation of hypoxiainducible factor-1alpha and vascular endothelial growth factor expression in rats
    • Wang C, Weihrauch D, Schwabe DA, Bienengraeber M, Warltier DC, Kersten JR, et al. Extracellular signal-regulated kinases trigger isoflurane preconditioning concomitant with upregulation of hypoxiainducible factor-1alpha and vascular endothelial growth factor expression in rats. Anesth Analg 2006; 103: 281-288
    • (2006) Anesth Analg , vol.103 , pp. 281-288
    • Wang, C.1    Weihrauch, D.2    Schwabe, D.A.3    Bienengraeber, M.4    Warltier, D.C.5    Kersten, J.R.6
  • 45
    • 39749147629 scopus 로고    scopus 로고
    • Isoflurane preconditioning decreases myocardial infarction in rabbits via up-regulation of hypoxia inducible factor 1 that is mediated by mammalian target of rapamycin
    • Raphael J, Zuo Z, Abedat S, Beeri R, Gozal Y. Isoflurane preconditioning decreases myocardial infarction in rabbits via up-regulation of hypoxia inducible factor 1 that is mediated by mammalian target of rapamycin. Anesthesiology 2008; 108: 415-425
    • (2008) Anesthesiology , vol.108 , pp. 415-425
    • Raphael, J.1    Zuo, Z.2    Abedat, S.3    Beeri, R.4    Gozal, Y.5
  • 46
    • 41149172245 scopus 로고    scopus 로고
    • Cardiac remodelling hinders activation of cyclooxygenase-2, diminishing protection by delayed pharmacological preconditioning: Role of HIF1 alpha and CREB
    • Feng J, Lucchinetti E, Fischer G, Zhu M, Zaugg K, Schaub MC, et al. Cardiac remodelling hinders activation of cyclooxygenase-2, diminishing protection by delayed pharmacological preconditioning: role of HIF1 alpha and CREB. Cardiovasc Res 2008;78: 98-107.
    • (2008) Cardiovasc Res , vol.78 , pp. 98-107
    • Feng, J.1    Lucchinetti, E.2    Fischer, G.3    Zhu, M.4    Zaugg, K.5    Schaub, M.C.6
  • 47
    • 0037108807 scopus 로고    scopus 로고
    • Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
    • Ivan M, Haberberger T, Gervasi DC, Michelson KS, Gunzler V, Kondo K, et al. Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor. Proc Natl Acad Sci USA 2002; 99: 13459-13464
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13459-13464
    • Ivan, M.1    Haberberger, T.2    Gervasi, D.C.3    Michelson, K.S.4    Gunzler, V.5    Kondo, K.6
  • 48
    • 23744443462 scopus 로고    scopus 로고
    • HIF-1 activation attenuates postischemic myocardial injury: Role for heme oxygenase-1 in modulating microvascular chemokine generation
    • Ockaili R, Natarajan R, Salloum F, Fisher BJ, Jones D, Fowler AA III, et al. HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in modulating microvascular chemokine generation. Am J Physiol Heart Circ Physiol 2005; 289: H542-8.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Ockaili, R.1    Natarajan, R.2    Salloum, F.3    Fisher, B.J.4    Jones, D.5    Fowler III, A.A.6
  • 49
    • 4243550127 scopus 로고    scopus 로고
    • Heme oxygenase/carbon monoxide signaling pathways: Regulation and functional significance
    • 249-263
    • Ryter SW, Otterbein LE, Morse D, Choi AM. Heme oxygenase/carbon monoxide signaling pathways: regulation and functional significance. Mol Cell Biochem 2002; 234-235: 249-263
    • (2002) Mol Cell Biochem , pp. 234-235
    • Ryter, S.W.1    Otterbein, L.E.2    Morse, D.3    Choi, A.M.4
  • 50
    • 42949089902 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1 improves the actions of nitric oxide and natriuretic peptides after simulated ischemia-reperfusion
    • Luciano JA, Tan T, Zhang Q, Huang E, Scholz P, Weiss HR. Hypoxia inducible factor-1 improves the actions of nitric oxide and natriuretic peptides after simulated ischemia-reperfusion. Cell Physiol Biochem 2008; 21: 421-428
    • (2008) Cell Physiol Biochem , vol.21 , pp. 421-428
    • Luciano, J.A.1    Tan, T.2    Zhang, Q.3    Huang, E.4    Scholz, P.5    Weiss, H.R.6
  • 51
    • 69949091358 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1 improves the actions of positive inotropic agents in stunned cardiac myocytes
    • Tan T, Luciano JA, Scholz PM, Weiss HR. Hypoxia inducible factor-1 improves the actions of positive inotropic agents in stunned cardiac myocytes. Clin Exp Pharmacol Physiol 2009; 36: 904-911
    • (2009) Clin Exp Pharmacol Physiol , vol.36 , pp. 904-911
    • Tan, T.1    Luciano, J.A.2    Scholz, P.M.3    Weiss, H.R.4
  • 52
    • 77955982949 scopus 로고    scopus 로고
    • Chronic inhibition of hypoxia-inducible factor (hif) prolyl 4-hydroxylase improves ventricular performance, remodeling and vascularity following myocardial infarction in the rat
    • doi: 10.1097/FJC.0b013e3181e2bfef
    • Bao W, Qin P, Needle S, Erickson-Miller CL, Duffy KJ, Ariazi JL, et al. Chronic inhibition of hypoxia-inducible factor (hif) prolyl 4-hydroxylase improves ventricular performance, remodeling and vascularity following myocardial infarction in the rat. J Cardiovasc Pharmacol 2010. doi: 10.1097/FJC.0b013e3181e2bfef
    • (2010) J Cardiovasc Pharmacol
    • Bao, W.1    Qin, P.2    Needle, S.3    Erickson-Miller, C.L.4    Duffy, K.J.5    Ariazi, J.L.6
  • 53
    • 33644837102 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury
    • Natarajan R, Salloum FN, Fisher BJ, Kukreja RC, Fowler AA III. Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury. Circ Res 2006; 98: 133-140
    • (2006) Circ Res , vol.98 , pp. 133-140
    • Natarajan, R.1    Salloum, F.N.2    Fisher, B.J.3    Kukreja, R.C.4    Fowler III, A.A.5
  • 54
    • 34548461228 scopus 로고    scopus 로고
    • Activation of hypoxia-inducible factor-1 via prolyl-4 hydoxylase-2 gene silencing attenuates acute inflammatory responses in postischemic myocardium
    • Natarajan R, Salloum FN, Fisher BJ, Ownby ED, Kukreja RC, Fowler AA III. Activation of hypoxia-inducible factor-1 via prolyl-4 hydoxylase-2 gene silencing attenuates acute inflammatory responses in postischemic myocardium. Am J Physiol Heart Circ Physiol 2007; 293: H1571-80.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Natarajan, R.1    Salloum, F.N.2    Fisher, B.J.3    Ownby, E.D.4    Kukreja, R.C.5    Fowler III, A.A.6
  • 55
    • 39749087544 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1 upregulates adiponectin in diabetic mouse hearts and attenuates post-ischemic injury
    • Natarajan R, Salloum FN, Fisher BJ, Kukreja RC, Fowler AA III. Hypoxia inducible factor-1 upregulates adiponectin in diabetic mouse hearts and attenuates post-ischemic injury. J Cardiovasc Pharmacol 2008; 51: 178-187
    • (2008) J Cardiovasc Pharmacol , vol.51 , pp. 178-187
    • Natarajan, R.1    Salloum, F.N.2    Fisher, B.J.3    Kukreja, R.C.4    Fowler III, A.A.5
  • 56
    • 68049116920 scopus 로고    scopus 로고
    • Prolyl hydroxylase inhibition attenuates post-ischemic cardiac injury via induction of endoplasmic reticulum stress genes
    • Natarajan R, Salloum FN, Fisher BJ, Smithson L, Almenara J, Fowler AA III. Prolyl hydroxylase inhibition attenuates post-ischemic cardiac injury via induction of endoplasmic reticulum stress genes. Vascul Pharmacol 2009; 51: 110-118
    • (2009) Vascul Pharmacol , vol.51 , pp. 110-118
    • Natarajan, R.1    Salloum, F.N.2    Fisher, B.J.3    Smithson, L.4    Almenara, J.5    Fowler III, A.A.6
  • 57
    • 0036275028 scopus 로고    scopus 로고
    • Intramyocardial injection of naked DNA encoding HIF-1alpha/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat
    • Shyu KG, Wang MT, Wang BW, Chang CC, Leu JG, Kuan P, et al. Intramyocardial injection of naked DNA encoding HIF-1alpha/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat. Cardiovasc Res. 2002; 54: 576-583
    • (2002) Cardiovasc Res. , vol.54 , pp. 576-583
    • Shyu, K.G.1    Wang, M.T.2    Wang, B.W.3    Chang, C.C.4    Leu, J.G.5    Kuan, P.6
  • 58
    • 12144257637 scopus 로고    scopus 로고
    • Expression of constitutively stable hybrid hypoxia-inducible factor-1alpha protects cultured rat cardiomyocytes against simulated ischemia-reperfusion injury
    • Date T, Mochizuki S, Belanger AJ, Yamakawa M, Luo Z, Vincent KA, et al. Expression of constitutively stable hybrid hypoxia-inducible factor-1alpha protects cultured rat cardiomyocytes against simulated ischemia-reperfusion injury. Am J Physiol Cell Physiol 2005; 288: C314-20.
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Date, T.1    Mochizuki, S.2    Belanger, A.J.3    Yamakawa, M.4    Luo, Z.5    Vincent, K.A.6
  • 59
    • 62349083271 scopus 로고    scopus 로고
    • In vivo remote delivery of DNA encoding for hypoxia-inducible factor 1 alpha reduces myocardial infarct size
    • Czibik G, Martinov V, Ruusalepp A, Sagave J, Skare O, Valen G. In vivo remote delivery of DNA encoding for hypoxia-inducible factor 1 alpha reduces myocardial infarct size. Clin Transl Sci 2009; 2: 33-40.
    • (2009) Clin Transl Sci , vol.2 , pp. 33-40
    • Czibik, G.1    Martinov, V.2    Ruusalepp, A.3    Sagave, J.4    Skare, O.5    Valen, G.6
  • 60
    • 33847197568 scopus 로고    scopus 로고
    • Protection against myocardial ischemia-reperfusion injury by the angiogenic Masterswitch protein PR 39 gene therapy: The roles of HIF1alpha stabilization and FGFR1 signaling
    • Muinck ED, Nagy N, Tirziu D, Murakami M, Gurusamy N, Goswami SK, et al. Protection against myocardial ischemia-reperfusion injury by the angiogenic Masterswitch protein PR 39 gene therapy: the roles of HIF1alpha stabilization and FGFR1 signaling. Antioxid Redox Signal 2007; 9: 437-445
    • (2007) Antioxid Redox Signal , vol.9 , pp. 437-445
    • Muinck, E.D.1    Nagy, N.2    Tirziu, D.3    Murakami, M.4    Gurusamy, N.5    Goswami, S.K.6
  • 61
    • 65249185780 scopus 로고    scopus 로고
    • Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes
    • Rane S, He M, Sayed D, Vashistha H, Malhotra A, Sadoshima J, et al. Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes. Circ Res 2009; 104: 879-886
    • (2009) Circ Res , vol.104 , pp. 879-886
    • Rane, S.1    He, M.2    Sayed, D.3    Vashistha, H.4    Malhotra, A.5    Sadoshima, J.6
  • 62
    • 28244446238 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1-alpha reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse
    • Kido M, Du L, Sullivan CC, Li X, Deutsch R, Jamieson SW, et al. Hypoxia-inducible factor 1-alpha reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse. J Am Coll Cardiol 2005; 46: 2116-2124
    • (2005) J Am Coll Cardiol , vol.46 , pp. 2116-2124
    • Kido, M.1    Du, L.2    Sullivan, C.C.3    Li, X.4    Deutsch, R.5    Jamieson, S.W.6
  • 63
    • 42449163874 scopus 로고    scopus 로고
    • Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
    • Minamishima YA, Moslehi J, Bardeesy N, Cullen D, Bronson RT, Kaelin WG Jr. Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure. Blood 2008; 111: 3236-3244
    • (2008) Blood , vol.111 , pp. 3236-3244
    • Minamishima, Y.A.1    Moslehi, J.2    Bardeesy, N.3    Cullen, D.4    Bronson, R.T.5    Kaelin Jr., W.G.6
  • 64
    • 77951552411 scopus 로고    scopus 로고
    • Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemiareperfusion injury
    • Hyvarinen J, Hassinen IE, Sormunen R, Maki JM, Kivirikko KI, Koivunen P, et al. Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemiareperfusion injury. J Biol Chem 2010; 285: 13646-13657
    • (2010) J Biol Chem , vol.285 , pp. 13646-13657
    • Hyvarinen, J.1    Hassinen, I.E.2    Sormunen, R.3    Maki, J.M.4    Kivirikko, K.I.5    Koivunen, P.6
  • 65
    • 70350060135 scopus 로고    scopus 로고
    • Exercise preconditioning of the myocardium
    • Kavazis AN. Exercise preconditioning of the myocardium. Sports Med 2009; 39: 923-935
    • (2009) Sports Med , vol.39 , pp. 923-935
    • Kavazis, A.N.1
  • 66
    • 69549105882 scopus 로고    scopus 로고
    • Gene expression profile of rat left ventricles reveals persisting changes following chronic mild exercise protocol: Implications for cardioprotection
    • Giusti B, Marini M, Rossi L, Lapini I, Magi A, Capalbo A, et al. Gene expression profile of rat left ventricles reveals persisting changes following chronic mild exercise protocol: implications for cardioprotection. BMC Genomics. 2009; 10: 342.
    • (2009) BMC Genomics. , vol.10 , pp. 342
    • Giusti, B.1    Marini, M.2    Rossi, L.3    Lapini, I.4    Magi, A.5    Capalbo, A.6
  • 68
    • 0031957221 scopus 로고    scopus 로고
    • Cardiac hypertrophy in chronically anemic fetal sheep: Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1
    • Martin C, Yu AY, Jiang BH, Davis L, Kimberly D, Hohimer AR, et al. Cardiac hypertrophy in chronically anemic fetal sheep: Increased vascularization is associated with increased myocardial expression of vascular endothelial growth factor and hypoxia-inducible factor 1. Am J Obstet Gynecol 1998; 178: 527-534
    • (1998) Am J Obstet Gynecol , vol.178 , pp. 527-534
    • Martin, C.1    Yu, A.Y.2    Jiang, B.H.3    Davis, L.4    Kimberly, D.5    Hohimer, A.R.6
  • 69
    • 35248887983 scopus 로고    scopus 로고
    • Regulation of tissue perfusion in mammals by hypoxiainducible factor 1
    • Semenza GL. Regulation of tissue perfusion in mammals by hypoxiainducible factor 1. Exp Physiol 2007; 92: 988-991
    • (2007) Exp Physiol , vol.92 , pp. 988-991
    • Semenza, G.L.1
  • 70
    • 48449094505 scopus 로고    scopus 로고
    • Polyol pathway mediates iron-induced oxidative injury in ischemic-reperfused rat heart
    • Tang WH, Wu S, Wong TM, Chung SK, Chung SS. Polyol pathway mediates iron-induced oxidative injury in ischemic-reperfused rat heart. Free Radic Biol Med 2008; 45: 602-610
    • (2008) Free Radic Biol Med , vol.45 , pp. 602-610
    • Tang, W.H.1    Wu, S.2    Wong, T.M.3    Chung, S.K.4    Chung, S.S.5
  • 71
    • 13944284587 scopus 로고    scopus 로고
    • Carvedilol modulates the expression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in a rat model of volume-overload heart failure
    • Shyu KG, Lu MJ, Chang H, Sun HY, Wang BW, Kuan P. Carvedilol modulates the expression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in a rat model of volume-overload heart failure. J Card Fail 2005; 11: 152-159
    • (2005) J Card Fail , vol.11 , pp. 152-159
    • Shyu, K.G.1    Lu, M.J.2    Chang, H.3    Sun, H.Y.4    Wang, B.W.5    Kuan, P.6
  • 72
    • 21244479992 scopus 로고    scopus 로고
    • Carvedilol prevents cardiac hypertrophy and overexpression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in pressure-overloaded rat heart
    • Shyu KG, Liou JY, Wang BW, Fang WJ, Chang H. Carvedilol prevents cardiac hypertrophy and overexpression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in pressure-overloaded rat heart. J Biomed Sci 2005; 12: 409-420
    • (2005) J Biomed Sci , vol.12 , pp. 409-420
    • Shyu, K.G.1    Liou, J.Y.2    Wang, B.W.3    Fang, W.J.4    Chang, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.