Oxygen radicals released during ischemic preconditioning contribute to cardioprotection in the rabbit myocardium

Journal of Molecular and Cellular Cardiology

Volumn 29, Issue 1, 1997, Pages 207-216

  Baines, Christopher P ^a   Goto, Mahiko ^a   Downey, James M ^a,b  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTH ALABAMA   (United States)

Author keywords

Ischemic preconditioning; N 2 mercaptopropionylglycine; Oxygen radicals; Protein kinase C; Xanthine oxidase

Indexed keywords

ADENOSINE; BRADYKININ; HYPOXANTHINE; OXYGEN RADICAL; POLYMYXIN B; TETRAZOLIUM; TIOPRONIN; XANTHINE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONDITIONING; CONTROLLED STUDY; FEMALE; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT;

EID: 0030890196     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1996.0265     Document Type: Article

References (40)

1. AMBROSIO G, ZWEIER JL, DUILIO C, KUPPUSAMY P, SANTORO G, ELIA PP, TRITTO I, CIRILLO P, CONDORELLI M, CHIARIELLO M, FLAHERTY JT, 1993. Evidence that mitochondrial respiration is a source of potentially toxic oxygen free radicals in intact rabbit hearts subjected to ischemia and reflow. J Biol Chem 268: 18532-18541.
2. BYLER RM, SHERMAN NA, WALLNER NA, WALLNER JS, HORWITZ LD, 1994. Hydrogen peroxide cytotoxicity in cultured cardiac myocytes is iron dependent. Am J Physiol 266: R121-H127.
3. CHARLAT ML, O'NEILL PG, EGAN JM, ABERNATHY DR, MICHAEL LH, MYERS ML, ROBERTS R, BOLLI R, 1987. Evidence for a pathogenetic role of xanthine oxidase in the "stunned" myocardium. Am J Physiol 252: H566-H577.
4. COHEN MV, LIU Y, LIU GS, WANG P, WEINBRENNER C, CORDIS GA, DAS D, DOWNEY JM, 1996. Phospholipase D plays a role in ischemic preconditioning in rabbit heart. Circulation (in press).
5. DOWELL FJ, HAMILTON CA, MCMURRAY J, REID JL, 1993. Effects of a xanthine oxidase/hypoxanthine free radical and reactive oxygen species generating system on endothelial function in New Zealand white rabbit aortic rings. J Cardiovasc Pharmacol 22: 792-797.
6. DOWNEY JM, 1990. Free radicals and their involvement during long term myocardial ischemia and reperfusion. Annu Rev Physiol 52: 487-504.
7. DOWNEY JM, MIURA T, EDDY LJ, CHAMBERS DE, MELLERT T, HEARSE DJ, YELLON DM, 1987. Xanthine oxidase is not a source of free radicals in the ischemic rabbit heart. J Mol Cell Cardiol 19: 1053-1060.
8. GOPALAKRISHNA R, ANDERSON WB, 1989. Calcium and phospholipid independent activation of protein kinase C by selective oxidative modification of the regulatory domain. Proc Natl Acad Sci 86: 6758-6762.
9. 1 receptor agonist was blocked by staurosporine (Abstract). J Mol Cell Cardiol 26: CLII.
10. GOTO M, LIU Y, YANG X-M, ARDELL JL, COHEN MV, DOWNEY JM, 1995. The role of bradykinin in protection of ischemic preconditioning in rabbit hearts. Circ Res 77: 611-621.
11. HANSEN PR, 1995. Role of neutrophils in myocardial ischemia and reperfusion. Circulation 91: 1872-1885.
12. HORWITZ LD, FENNESSEY PV, SHIKES RH, KONG Y, 1994. Marked reduction in myocardial infarct size due to prolonged infusion of an antioxidant during reperfusion. Circulation 89: 1792-1801.
13. IWAMOTO T, MIURA T, ADACHI T, NOTO T, OGAWA T, TSUCHIDA A, IIMURA O, 1991. Myocardial infarct size-limiting effect of ischemic preconditioning was not attenuated by oxygen free-radical scavengers in the rabbit. Circulation 83: 1015-1022.
14. KLONER RA, PRZYKLENK K, WHITTAKER P, 1989. Deleterious effects of oxygen radicals in ischemia/reperfusion: Resolved and unresolved issues. Circulation 80: 1115-1127.
15. KUPPUSAMY P, ZWEIER JL, 1989. Characterization of free radical generation by xanthine oxidase. J Biol Chem 264: 9880-9884.
16. LIU Y, DOWNEY JM, 1992. Ischemic preconditioning protects against infarction in rat heart. Am J Physiol 263: H1107-H1112.
17. 1 adenosine receptors in rabbit heart. Circulation 84: 350-356.
18. 3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart. Cardiovasc Res 28: 1057-1061.
19. LIU Y, TSUCHIDA A, COHEN MV, DOWNEY JM, 1995. Pretreatment with angiotensin II activates protein kinase C and limits myocardial infarction in isolated rabbit hearts. J Mol Cell Cardiol 27: 883-892.
20. MITSOS SE, FANTONE JC, GALLAGHER KP, WALDEN KM, SIMPSON PJ, ABRAMS GD, SCHORK MA, LUCCHESI BR, 1986. Canine myocardial reperfusion injury: protection by a free radical scavenger, N-2-mercaptopropionyl glycine. J Cardiovasc Pharmacol 8: 978-988.
21. MURRY CE, RICHARD VJ, JENNINGS RB, REIMER KA, 1988. Preconditioning with ischemia: is the protective effect mediated by free radical-induced myocardial stunning? (Abstract). Circulation 78: II-77.
22. MUXFELDT M, SCHAPER W, 1987. The activity of xanthine oxidase in heart of pigs, guinea pigs, rabbits, rats, and humans. Basic Res Cardiol 82: 486-492.
23. NATARAJAN V, TAHER MM, ROEHM B, PARINANDI NL, SCHMID HHO, KISS Z, GARCIA JGN, 1993. Activation of endothelial cell phospholipase D by hydrogen peroxide and fatty acid hydroperoxide. J Biol Chem 268: 930-937.
24. O'NEILL P, CHARLAT M, MICHAEL L, ROBERTS R, BOLLI R, 1989. Influence of neutrophil depletion on myocardial function and flow after reversible ischemia. Am J Physiol 252:H341-H351.
25. RICHARD V, TRON C, THUILLEZ C, 1993. Ischaemic preconditioning is not mediated by oxygen derived free radicals in rats. Cardiovasc Res 27: 2016-2021.
26. SPEECHLY-DICK ME, MOCANU MM, YELLON DM, 1994. Protein kinase C: its role in ischemic preconditioning in the rat. Circ Res 75: 586-590.
27. SUN J-Z, TANG X-L, PARK S-W, QIU Y, TURRENS JF, BOLLI R, 1996. Evidence for an essential role of reactive oxygen species in the genesis of late preconditioning against myocardial stunning in conscious pigs. J Clin Invest 97: 562-576.
28. TANAKA M, FUJIWARA H, YAMASAKI K, SASAYAMA S, 1994. Superoxide dismutase and N-2-mercaptopropionyl glycine attenuate infarct size limitation effect of ischaemic preconditioning in the rabbit. Cardiovasc Res 28: 980-986.
29. THORNTON JD, LIU GS, OLSSON RA, DOWNEY JM, 1992. Intravenous pretreatment with Al-selective adenosine analogues protects the heart against infarction. Circulation 85: 659-665.
30. TRITTO I, SCOGNAMIGLIO A, ELIA P, DANDREA D, ERAMO N, ESPOSITO A, CIRILLO P, AMBROSIO G, 1993. Oxygen radicals may induce preconditioning in isolated hearts (Abstract). Circulation 88 (Suppl 2): I-569.
31. 1-Adrenergic agonists precondition rabbit ischemic myocardium independent of adenosine by direct ac-tivation of protein kinase C. Circ Res 75: 576-585.
32. URAIZEE A, REIMER KA, MURRY CE, JENNINGS RB, 1987. Failure of superoxide dismutase to limit size of myocardial infarction after 40 minutes of ischemia and 4 days of reperfusion in dogs. Circulation 75: 1237-1248.
33. VON RUECKER AA, HAN-JOEN BG, WILD M, BIDLINGMAIER F, 1989. Protein kinase C involvement in lipid peroxidation and cell membrane damage induced by oxygen based radicals in hepatocytes. Biochem Biophys Res Commun 163: 836-842.
34. WALL TM, SHEEHY R, HARTMAN JC, 1994. Role of bradykinin in myocardial preconditioning. J Pharmacol Exp Ther 270: 681-689.
35. WANG P, GALLAGHER KP, DOWNEY JM, COHEN MV, 1996. Pretreatment with endothelin-1 mimics ischemic preconditioning against infarction in isolated rabbit heart. J Mol Cell Cardiol 28: 579-588.
36. YANG X-M, BAXTER GF, HEADS RJ, YELLON DM, DOWNEY JM, COHEN MV, 1996. Infarct limitation of the second window of protection in a conscious rabbit model. Cardiovasc Res 31: 777-783.
37. YELLON DM, BAXTER GF, 1995. A "second window of protection" or delayed preconditioning phenomenon: future horizons for myocardial protection? J Mol Cell Cardiol 27: 1023-1034.
38. YELLON DM, ALKHULAIFI AM, BROWNE EE, PUGSLEY WB, 1992. Ischaemic preconditioning limits infarct size in the rat heart. Cardiovasc Res 26: 983-987.
39. YTREHUS K, LIU Y, DOWNEY JM, 1994. Preconditioning protects ischemic rabbit heart by protein kinase C activation. Am J Physiol 266: H1145-H1152.
40. ZWEIER JL, 1988. Measurement of superoxide-derived free radicals in the reperfused heart. J Biol Chem 263: 1353-1357.