The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity

Nature Cell Biology

Volumn 14, Issue 2, 2012, Pages 201-208

  Foxler, Daniel E ^a   Bridge, Katherine S ^a   James, Victoria ^a   Webb, Thomas M ^b   Mee, Maureen ^a   Wong, Sybil C K ^a   Feng, Yunfeng ^c   Constantin Teodosiu, Dumitru ^a   Petursdottir, Thorgunnur Eyfjord ^d   Bjornsson, Johannes ^d   Ingvarsson, Sigurdur ^e   Ratcliffe, Peter J ^f   Longmore, Gregory D ^c   Sharp, Tyson V ^a,g  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c WASHINGTON UNIVERSITY   (United States)

^d LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^e UNIVERSITY OF ICELAND   (Iceland)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

26S PROTEASOME; AJUBA PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIM PROTEIN; LIMD1 PROTEIN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLYL HYDROXYLASE 1; PROLYL HYDROXYLASE 3; PROTEASOME; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN; WTIP PROTEIN;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPOXIA; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

CELL HYPOXIA; CELL LINE, TUMOR; HEK293 CELLS; HELA CELLS; HUMANS; HYDROXYLATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIM DOMAIN PROTEINS; MODELS, BIOLOGICAL; POLYUBIQUITIN; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; RNA INTERFERENCE; TRANSFECTION; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITINATION; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 84856496317     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2424     Document Type: Article

References (41)

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