-
1
-
-
0036488531
-
Endocrine-responsive breast cancer and strategies for combating resistance
-
S. Ali, and R.C. Coombes Endocrine-responsive breast cancer and strategies for combating resistance Nat Rev Cancer 2 2 2002 101 112
-
(2002)
Nat Rev Cancer
, vol.2
, Issue.2
, pp. 101-112
-
-
Ali, S.1
Coombes, R.C.2
-
2
-
-
37649007431
-
W. Selective estrogen-receptor modulators and antihormonal resistance in breast cancer
-
V.C. Jordan W. Selective estrogen-receptor modulators and antihormonal resistance in breast cancer J Clin Oncol 25 36 2007 5815 5824
-
(2007)
J Clin Oncol
, vol.25
, Issue.36
, pp. 5815-5824
-
-
Jordan, V.C.1
-
3
-
-
69249137029
-
Biological determinants of endocrine resistance in breast cancer
-
E.A. Musgrove, and R.L. Sutherland Biological determinants of endocrine resistance in breast cancer Nat Rev Cancer 9 9 2009 631 643
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.9
, pp. 631-643
-
-
Musgrove, E.A.1
Sutherland, R.L.2
-
4
-
-
0034680102
-
Molecular portraits of human breast tumours
-
C.M. Perou Molecular portraits of human breast tumours Nature 406 6797 2000 747 752
-
(2000)
Nature
, vol.406
, Issue.6797
, pp. 747-752
-
-
Perou, C.M.1
-
5
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
T. Sorlie Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications Proc Natl Acad Sci USA 98 19 2001 10869 10874
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.19
, pp. 10869-10874
-
-
Sorlie, T.1
-
6
-
-
28344454000
-
Molecular classification and molecular forecasting of breast cancer: Ready for clinical application?
-
J.D. Brenton Molecular classification and molecular forecasting of breast cancer: ready for clinical application? J Clin Oncol 23 29 2005 7350 7360
-
(2005)
J Clin Oncol
, vol.23
, Issue.29
, pp. 7350-7360
-
-
Brenton, J.D.1
-
7
-
-
60849097255
-
Gene-expression signatures in breast cancer
-
C. Sotiriou, and L. Pusztai Gene-expression signatures in breast cancer N Engl J Med 360 8 2009 790 800
-
(2009)
N Engl J Med
, vol.360
, Issue.8
, pp. 790-800
-
-
Sotiriou, C.1
Pusztai, L.2
-
8
-
-
67650252530
-
Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery
-
J. Kao Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery PLoS One 4 7 2009 e6146
-
(2009)
PLoS One
, vol.4
, Issue.7
, pp. 6146
-
-
Kao, J.1
-
9
-
-
0023913120
-
The steroid and thyroid hormone receptor superfamily
-
R.M. Evans The steroid and thyroid hormone receptor superfamily Science 240 4854 1988 889 895
-
(1988)
Science
, vol.240
, Issue.4854
, pp. 889-895
-
-
Evans, R.M.1
-
10
-
-
0012473279
-
The nuclear receptor superfamily: The second decade
-
D.J. Mangelsdorf The nuclear receptor superfamily: the second decade Cell 83 6 1995 835 839
-
(1995)
Cell
, vol.83
, Issue.6
, pp. 835-839
-
-
Mangelsdorf, D.J.1
-
11
-
-
0030579801
-
Cloning of a novel receptor expressed in rat prostate and ovary
-
G.G. Kuiper Cloning of a novel receptor expressed in rat prostate and ovary Proc Natl Acad Sci USA 93 12 1996 5925 5930
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.12
, pp. 5925-5930
-
-
Kuiper, G.G.1
-
12
-
-
0030593681
-
ER beta: Identification and characterization of a novel human estrogen receptor
-
S. Mosselman, J. Polman, and R. Dijkema ER beta: identification and characterization of a novel human estrogen receptor FEBS Lett 392 1 1996 49 53
-
(1996)
FEBS Lett
, vol.392
, Issue.1
, pp. 49-53
-
-
Mosselman, S.1
Polman, J.2
Dijkema, R.3
-
13
-
-
33751542905
-
International union of pharmacology. LXIV. Estrogen receptors
-
K. Dahlman-Wright International union of pharmacology. LXIV. Estrogen receptors Pharmacol Rev 58 4 2006 773 781
-
(2006)
Pharmacol Rev
, vol.58
, Issue.4
, pp. 773-781
-
-
Dahlman-Wright, K.1
-
14
-
-
0034485142
-
Estrogen receptor alpha in human breast cancer: Occurrence and significance
-
S. Ali, and R.C. Coombes Estrogen receptor alpha in human breast cancer: occurrence and significance J Mammary Gland Biol Neoplasia 5 3 2000 271 281
-
(2000)
J Mammary Gland Biol Neoplasia
, vol.5
, Issue.3
, pp. 271-281
-
-
Ali, S.1
Coombes, R.C.2
-
15
-
-
0033856986
-
Functional differences between the amino-terminal domains of estrogen receptors alpha and beta
-
F. Delaunay Functional differences between the amino-terminal domains of estrogen receptors alpha and beta Mol Pharmacol 58 3 2000 584 590
-
(2000)
Mol Pharmacol
, vol.58
, Issue.3
, pp. 584-590
-
-
Delaunay, F.1
-
16
-
-
0034868904
-
ER beta inhibits proliferation and invasion of breast cancer cells
-
G. Lazennec ER beta inhibits proliferation and invasion of breast cancer cells Endocrinology 142 9 2001 4120 4130
-
(2001)
Endocrinology
, vol.142
, Issue.9
, pp. 4120-4130
-
-
Lazennec, G.1
-
17
-
-
1642535535
-
Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest
-
S. Paruthiyil Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest Cancer Res 64 1 2004 423 428
-
(2004)
Cancer Res
, vol.64
, Issue.1
, pp. 423-428
-
-
Paruthiyil, S.1
-
18
-
-
0017354142
-
Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells
-
R.J. Pietras, and C.M. Szego Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells Nature 265 5589 1977 69 72
-
(1977)
Nature
, vol.265
, Issue.5589
, pp. 69-72
-
-
Pietras, R.J.1
Szego, C.M.2
-
19
-
-
0029669930
-
Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells
-
A. Migliaccio Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells Embo J 15 6 1996 1292 1300
-
(1996)
Embo J
, vol.15
, Issue.6
, pp. 1292-1300
-
-
Migliaccio, A.1
-
20
-
-
0036224417
-
Cellular functions of plasma membrane estrogen receptors
-
E.R. Levin Cellular functions of plasma membrane estrogen receptors Steroids 67 6 2002 471 475
-
(2002)
Steroids
, vol.67
, Issue.6
, pp. 471-475
-
-
Levin, E.R.1
-
21
-
-
14844343093
-
A transmembrane intracellular estrogen receptor mediates rapid cell signaling
-
C.M. Revankar A transmembrane intracellular estrogen receptor mediates rapid cell signaling Science 307 5715 2005 1625 1630
-
(2005)
Science
, vol.307
, Issue.5715
, pp. 1625-1630
-
-
Revankar, C.M.1
-
22
-
-
34447523339
-
Estrogen receptors: How do they signal and what are their targets
-
N. Heldring Estrogen receptors: how do they signal and what are their targets Physiol Rev 87 3 2007 905 931
-
(2007)
Physiol Rev
, vol.87
, Issue.3
, pp. 905-931
-
-
Heldring, N.1
-
23
-
-
81255186483
-
Cracking the estrogen receptor's posttranslational code in breast tumors
-
M. Le Romancer Cracking the estrogen receptor's posttranslational code in breast tumors Endocr Rev 32 5 2011 587 622
-
(2011)
Endocr Rev
, vol.32
, Issue.5
, pp. 587-622
-
-
Le Romancer, M.1
-
24
-
-
0025337581
-
The non-DNA-binding heterooligomeric form of mammalian steroid hormone receptors contains a hsp90-bound 59-kilodalton protein
-
J.M. Renoir The non-DNA-binding heterooligomeric form of mammalian steroid hormone receptors contains a hsp90-bound 59-kilodalton protein J Biol Chem 265 18 1990 10740 10745
-
(1990)
J Biol Chem
, vol.265
, Issue.18
, pp. 10740-10745
-
-
Renoir, J.M.1
-
25
-
-
0028911171
-
Subunit structure of the nonactivated human estrogen receptor
-
B. Segnitz, and U. Gehring Subunit structure of the nonactivated human estrogen receptor Proc Natl Acad Sci USA 92 6 1995 2179 2183
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.6
, pp. 2179-2183
-
-
Segnitz, B.1
Gehring, U.2
-
26
-
-
0030982641
-
The role of the hsp90-based chaperone system in signal transduction by nuclear receptors and receptors signaling via MAP kinase
-
W.B. Pratt The role of the hsp90-based chaperone system in signal transduction by nuclear receptors and receptors signaling via MAP kinase Annu Rev Pharmacol Toxicol 37 1997 297 326
-
(1997)
Annu Rev Pharmacol Toxicol
, vol.37
, pp. 297-326
-
-
Pratt, W.B.1
-
27
-
-
18144405740
-
Estrogen receptor alpha and beta subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells
-
A. Gougelet Estrogen receptor alpha and beta subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells J Steroid Biochem Mol Biol 94 1-3 2005 71 81
-
(2005)
J Steroid Biochem Mol Biol
, vol.94
, Issue.13
, pp. 71-81
-
-
Gougelet, A.1
-
28
-
-
0033305547
-
Nuclear receptor coregulators: Cellular and molecular biology
-
N.J. McKenna, R.B. Lanz, and B.W. O'Malley Nuclear receptor coregulators: cellular and molecular biology Endocr Rev 20 3 1999 321 344
-
(1999)
Endocr Rev
, vol.20
, Issue.3
, pp. 321-344
-
-
McKenna, N.J.1
Lanz, R.B.2
O'Malley, B.W.3
-
29
-
-
0034650893
-
The coregulator exchange in transcriptional functions of nuclear receptors
-
C.K. Glass, and M.G. Rosenfeld The coregulator exchange in transcriptional functions of nuclear receptors Genes Dev 14 2 2000 121 141
-
(2000)
Genes Dev
, vol.14
, Issue.2
, pp. 121-141
-
-
Glass, C.K.1
Rosenfeld, M.G.2
-
30
-
-
0037154974
-
Combinatorial control of gene expression by nuclear receptors and coregulators
-
N.J. McKenna, and B.W. O'Malley Combinatorial control of gene expression by nuclear receptors and coregulators Cell 108 4 2002 465 474
-
(2002)
Cell
, vol.108
, Issue.4
, pp. 465-474
-
-
McKenna, N.J.1
O'Malley, B.W.2
-
31
-
-
2642544592
-
Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter
-
R. Metivier Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter Cell 115 6 2003 751 763
-
(2003)
Cell
, vol.115
, Issue.6
, pp. 751-763
-
-
Metivier, R.1
-
32
-
-
0035813090
-
Coregulator codes of transcriptional regulation by nuclear receptors
-
M.G. Rosenfeld, and C.K. Glass Coregulator codes of transcriptional regulation by nuclear receptors J Biol Chem 276 40 2001 36865 36868
-
(2001)
J Biol Chem
, vol.276
, Issue.40
, pp. 36865-36868
-
-
Rosenfeld, M.G.1
Glass, C.K.2
-
33
-
-
34548307042
-
The silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) corepressor is required for full estrogen receptor alpha transcriptional activity
-
T.J. Peterson The silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) corepressor is required for full estrogen receptor alpha transcriptional activity Mol Cell Biol 27 17 2007 5933 5948
-
(2007)
Mol Cell Biol
, vol.27
, Issue.17
, pp. 5933-5948
-
-
Peterson, T.J.1
-
34
-
-
0034731452
-
Synergistic, p160 coactivator-dependent enhancement of estrogen receptor function by CARM1 and p300
-
D. Chen, S.M. Huang, and M.R. Stallcup Synergistic, p160 coactivator-dependent enhancement of estrogen receptor function by CARM1 and p300 J Biol Chem 275 52 2000 40810 40816
-
(2000)
J Biol Chem
, vol.275
, Issue.52
, pp. 40810-40816
-
-
Chen, D.1
Huang, S.M.2
Stallcup, M.R.3
-
35
-
-
0034735861
-
Estrogen receptor pathways to AP-1
-
P.J. Kushner Estrogen receptor pathways to AP-1 J Steroid Biochem Mol Biol 74 5 2000 311 317
-
(2000)
J Steroid Biochem Mol Biol
, vol.74
, Issue.5
, pp. 311-317
-
-
Kushner, P.J.1
-
36
-
-
0032031082
-
Ligand-independent activation of the estrogen receptors alpha and beta by mutations of a conserved tyrosine can be abolished by antiestrogens
-
G.B. Tremblay Ligand-independent activation of the estrogen receptors alpha and beta by mutations of a conserved tyrosine can be abolished by antiestrogens Cancer Res 58 5 1998 877 881
-
(1998)
Cancer Res
, vol.58
, Issue.5
, pp. 877-881
-
-
Tremblay, G.B.1
-
37
-
-
33947541885
-
The hormonal response of estrogen receptor beta is decreased by the phosphatidylinositol 3-kinase/Akt pathway via a phosphorylation-dependent release of CREB-binding protein
-
M. Sanchez The hormonal response of estrogen receptor beta is decreased by the phosphatidylinositol 3-kinase/Akt pathway via a phosphorylation-dependent release of CREB-binding protein J Biol Chem 282 7 2007 4830 4840
-
(2007)
J Biol Chem
, vol.282
, Issue.7
, pp. 4830-4840
-
-
Sanchez, M.1
-
38
-
-
0033120030
-
Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1
-
A. Tremblay Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1 Mol Cell 3 4 1999 513 519
-
(1999)
Mol Cell
, vol.3
, Issue.4
, pp. 513-519
-
-
Tremblay, A.1
-
39
-
-
38849141014
-
Phosphorylation of activation function-1 regulates proteasome-dependent nuclear mobility and E6-associated protein ubiquitin ligase recruitment to the estrogen receptor {beta}
-
N. Picard Phosphorylation of activation function-1 regulates proteasome-dependent nuclear mobility and E6-associated protein ubiquitin ligase recruitment to the estrogen receptor {beta} Mol Endocrinol 22 2 2008 317 330
-
(2008)
Mol Endocrinol
, vol.22
, Issue.2
, pp. 317-330
-
-
Picard, N.1
-
40
-
-
85011457699
-
EM-800, a novel antiestrogen, acts as a pure antagonist of the transcriptional functions of estrogen receptors alpha and beta
-
A. Tremblay EM-800, a novel antiestrogen, acts as a pure antagonist of the transcriptional functions of estrogen receptors alpha and beta Endocrinology 139 1 1998 111 118
-
(1998)
Endocrinology
, vol.139
, Issue.1
, pp. 111-118
-
-
Tremblay, A.1
-
41
-
-
0033542402
-
The protective effects of estrogen on the cardiovascular system
-
M.E. Mendelsohn, and R.H. Karas The protective effects of estrogen on the cardiovascular system N Engl J Med 340 23 1999 1801 1811
-
(1999)
N Engl J Med
, vol.340
, Issue.23
, pp. 1801-1811
-
-
Mendelsohn, M.E.1
Karas, R.H.2
-
42
-
-
77953539851
-
Coadministration of nanosystems of short silencing RNAs targeting oestrogen receptor alpha and anti-oestrogen synergistically induces tumour growth inhibition in human breast cancer xenografts
-
C. Bouclier Coadministration of nanosystems of short silencing RNAs targeting oestrogen receptor alpha and anti-oestrogen synergistically induces tumour growth inhibition in human breast cancer xenografts Breast Cancer Res Treat 122 1 2010 145 158
-
(2010)
Breast Cancer Res Treat
, vol.122
, Issue.1
, pp. 145-158
-
-
Bouclier, C.1
-
43
-
-
84862539695
-
Stromal estrogen receptor-alpha promotes tumor growth by normalizing an increased angiogenesis
-
C. Pequeux Stromal estrogen receptor-alpha promotes tumor growth by normalizing an increased angiogenesis Cancer Res 72 12 2012 3010 3019
-
(2012)
Cancer Res
, vol.72
, Issue.12
, pp. 3010-3019
-
-
Pequeux, C.1
-
44
-
-
0032569831
-
Tamoxifen in the treatment of breast cancer
-
C.K. Osborne Tamoxifen in the treatment of breast cancer N Engl J Med 339 22 1998 1609 1618
-
(1998)
N Engl J Med
, vol.339
, Issue.22
, pp. 1609-1618
-
-
Osborne, C.K.1
-
45
-
-
8344275588
-
The biological role of estrogen receptors alpha and beta in cancer
-
S.T. Pearce, and V.C. Jordan The biological role of estrogen receptors alpha and beta in cancer Crit Rev Oncol Hematol 50 1 2004 3 22
-
(2004)
Crit Rev Oncol Hematol
, vol.50
, Issue.1
, pp. 3-22
-
-
Pearce, S.T.1
Jordan, V.C.2
-
46
-
-
0026585852
-
Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer
-
R.R. Love Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer N Engl J Med 326 13 1992 852 856
-
(1992)
N Engl J Med
, vol.326
, Issue.13
, pp. 852-856
-
-
Love, R.R.1
-
47
-
-
0035802285
-
Selective estrogen receptor modulation and reduction in risk of breast cancer, osteoporosis, and coronary heart disease
-
V.C. Jordan, S. Gapstur, and M. Morrow Selective estrogen receptor modulation and reduction in risk of breast cancer, osteoporosis, and coronary heart disease J Natl Cancer Inst 93 19 2001 1449 1457
-
(2001)
J Natl Cancer Inst
, vol.93
, Issue.19
, pp. 1449-1457
-
-
Jordan, V.C.1
Gapstur, S.2
Morrow, M.3
-
48
-
-
11744282298
-
Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes
-
R.M. Lavinsky Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes Proc Natl Acad Sci USA 95 6 1998 2920 2925
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.6
, pp. 2920-2925
-
-
Lavinsky, R.M.1
-
49
-
-
0030946198
-
Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen
-
C.L. Smith, Z. Nawaz, and B.W. O'Malley Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen Mol Endocrinol 11 6 1997 657 666
-
(1997)
Mol Endocrinol
, vol.11
, Issue.6
, pp. 657-666
-
-
Smith, C.L.1
Nawaz, Z.2
O'Malley, B.W.3
-
50
-
-
0032230350
-
Estrogen receptor activation function 1 works by binding p160 coactivator proteins
-
P. Webb Estrogen receptor activation function 1 works by binding p160 coactivator proteins Mol Endocrinol 12 10 1998 1605 1618
-
(1998)
Mol Endocrinol
, vol.12
, Issue.10
, pp. 1605-1618
-
-
Webb, P.1
-
51
-
-
0036375102
-
Definition of the molecular and cellular mechanisms underlying the tissue-selective agonist/antagonist activities of selective estrogen receptor modulators
-
D.P. McDonnell Definition of the molecular and cellular mechanisms underlying the tissue-selective agonist/antagonist activities of selective estrogen receptor modulators Recent Prog Horm Res 57 2002 295 316
-
(2002)
Recent Prog Horm Res
, vol.57
, pp. 295-316
-
-
McDonnell, D.P.1
-
52
-
-
0028208456
-
Endometrial cancer in tamoxifen-treated breast cancer patients: Findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14
-
B. Fisher Endometrial cancer in tamoxifen-treated breast cancer patients: findings from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-14 J Natl Cancer Inst 86 7 1994 527 537
-
(1994)
J Natl Cancer Inst
, vol.86
, Issue.7
, pp. 527-537
-
-
Fisher, B.1
-
53
-
-
0033514930
-
Proteasome-dependent degradation of the human estrogen receptor
-
Z. Nawaz Proteasome-dependent degradation of the human estrogen receptor Proc Natl Acad Sci USA 96 5 1999 1858 1862
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.5
, pp. 1858-1862
-
-
Nawaz, Z.1
-
54
-
-
0035929585
-
The human estrogen receptor-alpha is a ubiquitinated protein whose stability is affected differentially by agonists, antagonists, and selective estrogen receptor modulators
-
A.L. Wijayaratne, and D.P. McDonnell The human estrogen receptor-alpha is a ubiquitinated protein whose stability is affected differentially by agonists, antagonists, and selective estrogen receptor modulators J Biol Chem 276 38 2001 35684 35692
-
(2001)
J Biol Chem
, vol.276
, Issue.38
, pp. 35684-35692
-
-
Wijayaratne, A.L.1
McDonnell, D.P.2
-
55
-
-
0142056952
-
Various phosphorylation pathways, depending on agonist and antagonist binding to endogenous estrogen receptor alpha (ERalpha), differentially affect ERalpha extractability, proteasome-mediated stability, and transcriptional activity in human breast cancer cells
-
V. Marsaud Various phosphorylation pathways, depending on agonist and antagonist binding to endogenous estrogen receptor alpha (ERalpha), differentially affect ERalpha extractability, proteasome-mediated stability, and transcriptional activity in human breast cancer cells Mol Endocrinol 17 10 2003 2013 2027
-
(2003)
Mol Endocrinol
, vol.17
, Issue.10
, pp. 2013-2027
-
-
Marsaud, V.1
-
56
-
-
33748936381
-
Ligand-induced estrogen receptor alpha degradation by the proteasome: New actors?
-
M. Callige, and H. Richard-Foy Ligand-induced estrogen receptor alpha degradation by the proteasome: new actors? Nucl Recept Signal 4 2006 e004
-
(2006)
Nucl Recept Signal
, vol.4
, pp. 004
-
-
Callige, M.1
Richard-Foy, H.2
-
57
-
-
33645033984
-
ERalpha and ERbeta expression and transcriptional activity are differentially regulated by HDAC inhibitors
-
V. Duong ERalpha and ERbeta expression and transcriptional activity are differentially regulated by HDAC inhibitors Oncogene 25 12 2006 1799 1806
-
(2006)
Oncogene
, vol.25
, Issue.12
, pp. 1799-1806
-
-
Duong, V.1
-
58
-
-
2442648038
-
Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: A multinational, double-blind, randomized trial
-
A. Howell Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: a multinational, double-blind, randomized trial J Clin Oncol 22 9 2004 1605 1613
-
(2004)
J Clin Oncol
, vol.22
, Issue.9
, pp. 1605-1613
-
-
Howell, A.1
-
59
-
-
0034669484
-
Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: Results of a North American multicenter randomized trial. Arimidex Study Group
-
J.M. Nabholtz Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: results of a North American multicenter randomized trial. Arimidex Study Group J Clin Oncol 18 22 2000 3758 3767
-
(2000)
J Clin Oncol
, vol.18
, Issue.22
, pp. 3758-3767
-
-
Nabholtz, J.M.1
-
60
-
-
0343584508
-
Superior efficacy of letrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer: Results of a phase III study of the International Letrozole Breast Cancer Group
-
H. Mouridsen Superior efficacy of letrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer: results of a phase III study of the International Letrozole Breast Cancer Group J Clin Oncol 19 10 2001 2596 2606
-
(2001)
J Clin Oncol
, vol.19
, Issue.10
, pp. 2596-2606
-
-
Mouridsen, H.1
-
61
-
-
0037157603
-
Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomised trial
-
M. Baum Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial Lancet 359 9324 2002 2131 2139
-
(2002)
Lancet
, vol.359
, Issue.9324
, pp. 2131-2139
-
-
Baum, M.1
-
62
-
-
84865190386
-
Pilot neoadjuvant trial in HER2 positive breast cancer with combination of nab-paclitaxel and lapatinib
-
V.G. Kaklamani Pilot neoadjuvant trial in HER2 positive breast cancer with combination of nab-paclitaxel and lapatinib Breast Cancer Res Treat 132 3 2012 833 842
-
(2012)
Breast Cancer Res Treat
, vol.132
, Issue.3
, pp. 833-842
-
-
Kaklamani, V.G.1
-
63
-
-
11244257032
-
The dual ErbB1/ErbB2 inhibitor, lapatinib (GW572016), cooperates with tamoxifen to inhibit both cell proliferation- and estrogen-dependent gene expression in antiestrogen-resistant breast cancer
-
I. Chu The dual ErbB1/ErbB2 inhibitor, lapatinib (GW572016), cooperates with tamoxifen to inhibit both cell proliferation- and estrogen-dependent gene expression in antiestrogen-resistant breast cancer Cancer Res 65 1 2005 18 25
-
(2005)
Cancer Res
, vol.65
, Issue.1
, pp. 18-25
-
-
Chu, I.1
-
64
-
-
0036799626
-
Distinct nongenomic signal transduction pathways controlled by 17beta-estradiol regulate DNA synthesis and cyclin D(1) gene transcription in HepG2 cells
-
M. Marino Distinct nongenomic signal transduction pathways controlled by 17beta-estradiol regulate DNA synthesis and cyclin D(1) gene transcription in HepG2 cells Mol Biol Cell 13 10 2002 3720 3729
-
(2002)
Mol Biol Cell
, vol.13
, Issue.10
, pp. 3720-3729
-
-
Marino, M.1
-
65
-
-
0037184912
-
Integration of the non-genomic and genomic actions of estrogen. Membrane-initiated signaling by steroid to transcription and cell biology
-
A. Pedram Integration of the non-genomic and genomic actions of estrogen. Membrane-initiated signaling by steroid to transcription and cell biology J Biol Chem 277 52 2002 50768 50775
-
(2002)
J Biol Chem
, vol.277
, Issue.52
, pp. 50768-50775
-
-
Pedram, A.1
-
66
-
-
41149098579
-
Estrogen receptors outside the nucleus in breast cancer
-
E.R. Levin, and R.J. Pietras Estrogen receptors outside the nucleus in breast cancer Breast Cancer Res Treat 108 3 2008 351 361
-
(2008)
Breast Cancer Res Treat
, vol.108
, Issue.3
, pp. 351-361
-
-
Levin, E.R.1
Pietras, R.J.2
-
67
-
-
4344679375
-
Estrogen receptor-dependent activation of AP-1 via non-genomic signalling
-
L. Bjornstrom, and M. Sjoberg Estrogen receptor-dependent activation of AP-1 via non-genomic signalling Nucl Recept 2 1 2004 3
-
(2004)
Nucl Recept
, vol.2
, Issue.1
, pp. 3
-
-
Bjornstrom, L.1
Sjoberg, M.2
-
68
-
-
67449141657
-
Membrane-initiated actions of estrogen on the endothelium
-
K.H. Kim, and J.R. Bender Membrane-initiated actions of estrogen on the endothelium Mol Cell Endocrinol 308 1-2 2009 3 8
-
(2009)
Mol Cell Endocrinol
, vol.308
, Issue.12
, pp. 3-8
-
-
Kim, K.H.1
Bender, J.R.2
-
69
-
-
1242341918
-
The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane
-
R.X. Song The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane Proc Natl Acad Sci USA 101 7 2004 2076 2081
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.7
, pp. 2076-2081
-
-
Song, R.X.1
-
70
-
-
66349092194
-
Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway
-
I. Barone Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway Cancer Res 69 11 2009 4724 4732
-
(2009)
Cancer Res
, vol.69
, Issue.11
, pp. 4724-4732
-
-
Barone, I.1
-
71
-
-
77951557127
-
Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivity
-
I. Barone Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivity Oncogene 29 16 2010 2404 2414
-
(2010)
Oncogene
, vol.29
, Issue.16
, pp. 2404-2414
-
-
Barone, I.1
-
72
-
-
26844487041
-
Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: A supporting role to the epidermal growth factor receptor
-
J.M. Knowlden Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: a supporting role to the epidermal growth factor receptor Endocrinology 146 11 2005 4609 4618
-
(2005)
Endocrinology
, vol.146
, Issue.11
, pp. 4609-4618
-
-
Knowlden, J.M.1
-
73
-
-
33846882800
-
Role of receptor complexes in the extranuclear actions of estrogen receptor alpha in breast cancer
-
R.X. Song Role of receptor complexes in the extranuclear actions of estrogen receptor alpha in breast cancer Endocr Relat Cancer 13 Suppl. 1 2006 S3 S13
-
(2006)
Endocr Relat Cancer
, vol.13
, Issue.SUPPL. 1
-
-
Song, R.X.1
-
74
-
-
0036127836
-
Epidermal growth factor receptor (EGFR) transactivation by estrogen via the G-protein-coupled receptor, GPR30: A novel signaling pathway with potential significance for breast cancer
-
E.J. Filardo Epidermal growth factor receptor (EGFR) transactivation by estrogen via the G-protein-coupled receptor, GPR30: a novel signaling pathway with potential significance for breast cancer J Steroid Biochem Mol Biol 80 2 2002 231 238
-
(2002)
J Steroid Biochem Mol Biol
, vol.80
, Issue.2
, pp. 231-238
-
-
Filardo, E.J.1
-
75
-
-
0033780783
-
Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF
-
E.J. Filardo Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF Mol Endocrinol 14 10 2000 1649 1660
-
(2000)
Mol Endocrinol
, vol.14
, Issue.10
, pp. 1649-1660
-
-
Filardo, E.J.1
-
76
-
-
12344307170
-
Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
-
P. Thomas Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells Endocrinology 146 2 2005 624 632
-
(2005)
Endocrinology
, vol.146
, Issue.2
, pp. 624-632
-
-
Thomas, P.1
-
77
-
-
77950407928
-
Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling
-
L. Kang Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling Mol Endocrinol 24 4 2010 709 721
-
(2010)
Mol Endocrinol
, vol.24
, Issue.4
, pp. 709-721
-
-
Kang, L.1
-
78
-
-
84862737860
-
Minireview: G protein-coupled estrogen receptor-1, GPER-1: Its mechanism of action and role in female reproductive cancer. Renal and vascular physiology
-
E.J. Filardo, and P. Thomas Minireview: G protein-coupled estrogen receptor-1, GPER-1: its mechanism of action and role in female reproductive cancer. Renal and vascular physiology Endocrinology 153 7 2012 2953 2962
-
(2012)
Endocrinology
, vol.153
, Issue.7
, pp. 2953-2962
-
-
Filardo, E.J.1
Thomas, P.2
-
79
-
-
0036140032
-
Estrogen action via the G protein-coupled receptor, GPR30: Stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis
-
E.J. Filardo Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis Mol Endocrinol 16 1 2002 70 84
-
(2002)
Mol Endocrinol
, vol.16
, Issue.1
, pp. 70-84
-
-
Filardo, E.J.1
-
80
-
-
70350449695
-
G protein-coupled receptor 30 expression is up-regulated by EGF and TGF alpha in estrogen receptor alpha-positive cancer cells
-
A. Vivacqua G protein-coupled receptor 30 expression is up-regulated by EGF and TGF alpha in estrogen receptor alpha-positive cancer cells Mol Endocrinol 23 11 2009 1815 1826
-
(2009)
Mol Endocrinol
, vol.23
, Issue.11
, pp. 1815-1826
-
-
Vivacqua, A.1
-
81
-
-
75149186664
-
The unfolding stories of GPR30, a new membrane-bound estrogen receptor
-
M. Maggiolini, and D. Picard The unfolding stories of GPR30, a new membrane-bound estrogen receptor J Endocrinol 204 2 2010 105 114
-
(2010)
J Endocrinol
, vol.204
, Issue.2
, pp. 105-114
-
-
Maggiolini, M.1
Picard, D.2
-
82
-
-
47949111993
-
Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells
-
L. Albanito Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells Endocrinology 149 8 2008 3799 3808
-
(2008)
Endocrinology
, vol.149
, Issue.8
, pp. 3799-3808
-
-
Albanito, L.1
-
83
-
-
84855767653
-
MIBE acts as antagonist ligand of both estrogen receptor alpha and GPER in breast cancer cells
-
R. Lappano MIBE acts as antagonist ligand of both estrogen receptor alpha and GPER in breast cancer cells Breast Cancer Res 14 1 2012 R12
-
(2012)
Breast Cancer Res
, vol.14
, Issue.1
, pp. 12
-
-
Lappano, R.1
-
84
-
-
0033305438
-
Estrogen receptor null mice: What have we learned and where will they lead us?
-
J.F. Couse, and K.S. Korach Estrogen receptor null mice: what have we learned and where will they lead us? Endocr Rev 20 3 1999 358 417
-
(1999)
Endocr Rev
, vol.20
, Issue.3
, pp. 358-417
-
-
Couse, J.F.1
Korach, K.S.2
-
85
-
-
33748743807
-
Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells
-
E.C. Chang Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells Endocrinology 147 10 2006 4831 4842
-
(2006)
Endocrinology
, vol.147
, Issue.10
, pp. 4831-4842
-
-
Chang, E.C.1
-
86
-
-
33746908103
-
Gene expression preferentially regulated by tamoxifen in breast cancer cells and correlations with clinical outcome
-
J. Frasor Gene expression preferentially regulated by tamoxifen in breast cancer cells and correlations with clinical outcome Cancer Res 66 14 2006 7334 7340
-
(2006)
Cancer Res
, vol.66
, Issue.14
, pp. 7334-7340
-
-
Frasor, J.1
-
87
-
-
1242300083
-
Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D
-
A. Strom Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D Proc Natl Acad Sci USA 101 6 2004 1566 1571
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.6
, pp. 1566-1571
-
-
Strom, A.1
-
88
-
-
33845762296
-
Estrogen receptor beta inhibits angiogenesis and growth of T47D breast cancer xenografts
-
J. Hartman Estrogen receptor beta inhibits angiogenesis and growth of T47D breast cancer xenografts Cancer Res 66 23 2006 11207 11213
-
(2006)
Cancer Res
, vol.66
, Issue.23
, pp. 11207-11213
-
-
Hartman, J.1
-
89
-
-
29844458399
-
Estrogen receptor beta, a possible tumor suppressor involved in ovarian carcinogenesis
-
G. Lazennec Estrogen receptor beta, a possible tumor suppressor involved in ovarian carcinogenesis Cancer Lett 231 2 2006 151 157
-
(2006)
Cancer Lett
, vol.231
, Issue.2
, pp. 151-157
-
-
Lazennec, G.1
-
90
-
-
35848961688
-
The relevance of estrogen receptor-beta expression to the antiproliferative effects observed with histone deacetylase inhibitors and phytoestrogens in prostate cancer treatment
-
M. Stettner The relevance of estrogen receptor-beta expression to the antiproliferative effects observed with histone deacetylase inhibitors and phytoestrogens in prostate cancer treatment Mol Cancer Ther 6 10 2007 2626 2633
-
(2007)
Mol Cancer Ther
, vol.6
, Issue.10
, pp. 2626-2633
-
-
Stettner, M.1
-
91
-
-
0035866760
-
Decreased expression of estrogen receptor beta protein in proliferative preinvasive mammary tumors
-
P. Roger Decreased expression of estrogen receptor beta protein in proliferative preinvasive mammary tumors Cancer Res 61 6 2001 2537 2541
-
(2001)
Cancer Res
, vol.61
, Issue.6
, pp. 2537-2541
-
-
Roger, P.1
-
92
-
-
0036532167
-
Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor alpha and beta and show biological responses to estrogen
-
L.P. Stabile Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor alpha and beta and show biological responses to estrogen Cancer Res 62 7 2002 2141 2150
-
(2002)
Cancer Res
, vol.62
, Issue.7
, pp. 2141-2150
-
-
Stabile, L.P.1
-
93
-
-
0035878926
-
Frequent loss of estrogen receptor-beta expression in prostate cancer
-
L.G. Horvath Frequent loss of estrogen receptor-beta expression in prostate cancer Cancer Res 61 14 2001 5331 5335
-
(2001)
Cancer Res
, vol.61
, Issue.14
, pp. 5331-5335
-
-
Horvath, L.G.1
-
94
-
-
0034650410
-
Selective loss of estrogen receptor beta in malignant human colon
-
E.F. Foley Selective loss of estrogen receptor beta in malignant human colon Cancer Res 60 2 2000 245 248
-
(2000)
Cancer Res
, vol.60
, Issue.2
, pp. 245-248
-
-
Foley, E.F.1
-
95
-
-
77954584837
-
Estrogen receptor beta binds to and regulates three distinct classes of target genes
-
O.I. Vivar Estrogen receptor beta binds to and regulates three distinct classes of target genes J Biol Chem 285 29 2010 22059 22066
-
(2010)
J Biol Chem
, vol.285
, Issue.29
, pp. 22059-22066
-
-
Vivar, O.I.1
-
96
-
-
71849103610
-
Unliganded estrogen receptor-beta regulation of genes is inhibited by tamoxifen
-
N. Levy Unliganded estrogen receptor-beta regulation of genes is inhibited by tamoxifen Mol Cell Endocrinol 315 1-2 2010 201 207
-
(2010)
Mol Cell Endocrinol
, vol.315
, Issue.12
, pp. 201-207
-
-
Levy, N.1
-
97
-
-
43149093785
-
Estrogen receptor beta increases the efficacy of antiestrogens by effects on apoptosis and cell cycling in breast cancer cells
-
L. Hodges-Gallagher Estrogen receptor beta increases the efficacy of antiestrogens by effects on apoptosis and cell cycling in breast cancer cells Breast Cancer Res Treat 109 2 2008 241 250
-
(2008)
Breast Cancer Res Treat
, vol.109
, Issue.2
, pp. 241-250
-
-
Hodges-Gallagher, L.1
-
98
-
-
35348961982
-
Inhibition of histone deacetylase enhances the anti-proliferative action of antiestrogens on breast cancer cells and blocks tamoxifen-induced proliferation of uterine cells
-
L. Hodges-Gallagher Inhibition of histone deacetylase enhances the anti-proliferative action of antiestrogens on breast cancer cells and blocks tamoxifen-induced proliferation of uterine cells Breast Cancer Res Treat 105 3 2007 297 309
-
(2007)
Breast Cancer Res Treat
, vol.105
, Issue.3
, pp. 297-309
-
-
Hodges-Gallagher, L.1
-
99
-
-
0030925683
-
Steroid receptor interactions with heat shock protein and immunophilin chaperones
-
W.B. Pratt, and D.O. Toft Steroid receptor interactions with heat shock protein and immunophilin chaperones Endocr Rev 18 3 1997 306 360
-
(1997)
Endocr Rev
, vol.18
, Issue.3
, pp. 306-360
-
-
Pratt, W.B.1
Toft, D.O.2
-
100
-
-
33646114761
-
Hsp90 inhibitors: Small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation
-
B.S. Blagg, and T.D. Kerr Hsp90 inhibitors: small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation Med Res Rev 26 3 2006 310 338
-
(2006)
Med Res Rev
, vol.26
, Issue.3
, pp. 310-338
-
-
Blagg, B.S.1
Kerr, T.D.2
-
101
-
-
0035202753
-
The N-terminal adenosine triphosphate binding domain of Hsp90 is necessary and sufficient for interaction with estrogen receptor
-
L. Bouhouche-Chatelier, A. Chadli, and M.G. Catelli The N-terminal adenosine triphosphate binding domain of Hsp90 is necessary and sufficient for interaction with estrogen receptor Cell Stress Chaperones 6 4 2001 297 305
-
(2001)
Cell Stress Chaperones
, vol.6
, Issue.4
, pp. 297-305
-
-
Bouhouche-Chatelier, L.1
Chadli, A.2
Catelli, M.G.3
-
102
-
-
0030810984
-
The function of steroid hormone receptors is inhibited by the hsp90-specific compound geldanamycin
-
B. Segnitz, and U. Gehring The function of steroid hormone receptors is inhibited by the hsp90-specific compound geldanamycin J Biol Chem 272 30 1997 18694 18701
-
(1997)
J Biol Chem
, vol.272
, Issue.30
, pp. 18694-18701
-
-
Segnitz, B.1
Gehring, U.2
-
103
-
-
34248187981
-
Heat shock protein 90: The cancer chaperone
-
L. Neckers Heat shock protein 90: the cancer chaperone J Biosci 32 3 2007 517 530
-
(2007)
J Biosci
, vol.32
, Issue.3
, pp. 517-530
-
-
Neckers, L.1
-
104
-
-
33244484848
-
Targeting chaperones in transformed systems-a focus on Hsp90 and cancer
-
G. Chiosis Targeting chaperones in transformed systems-a focus on Hsp90 and cancer Expert Opin Ther Targets 10 1 2006 37 50
-
(2006)
Expert Opin Ther Targets
, vol.10
, Issue.1
, pp. 37-50
-
-
Chiosis, G.1
-
105
-
-
33746705661
-
Chaperoning steroid hormone action
-
D. Picard Chaperoning steroid hormone action Trends Endocrinol Metab 17 6 2006 229 235
-
(2006)
Trends Endocrinol Metab
, vol.17
, Issue.6
, pp. 229-235
-
-
Picard, D.1
-
106
-
-
25144435448
-
Hsp90 inhibitors identified from a library of novobiocin analogues
-
X.M. Yu Hsp90 inhibitors identified from a library of novobiocin analogues J Am Chem Soc 127 37 2005 12778 12779
-
(2005)
J Am Chem Soc
, vol.127
, Issue.37
, pp. 12778-12779
-
-
Yu, X.M.1
-
107
-
-
37849037720
-
New novobiocin analogues as antiproliferative agents in breast cancer cells and potential inhibitors of heat shock protein 90
-
G. Le Bras New novobiocin analogues as antiproliferative agents in breast cancer cells and potential inhibitors of heat shock protein 90 J Med Chem 50 24 2007 6189 6200
-
(2007)
J Med Chem
, vol.50
, Issue.24
, pp. 6189-6200
-
-
Le Bras, G.1
-
108
-
-
41349108858
-
Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90)
-
C. Radanyi Synthesis and biological activity of simplified denoviose-coumarins related to novobiocin as potent inhibitors of heat-shock protein 90 (hsp90) Bioorg Med Chem Lett 18 7 2008 2495 2498
-
(2008)
Bioorg Med Chem Lett
, vol.18
, Issue.7
, pp. 2495-2498
-
-
Radanyi, C.1
-
109
-
-
0034711270
-
The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone
-
M.G. Marcu The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone J Biol Chem 275 47 2000 37181 37186
-
(2000)
J Biol Chem
, vol.275
, Issue.47
, pp. 37181-37186
-
-
Marcu, M.G.1
-
110
-
-
34347352213
-
Proteasome-regulated ERBB2 and estrogen receptor pathways in breast cancer
-
C. Marx Proteasome-regulated ERBB2 and estrogen receptor pathways in breast cancer Mol Pharmacol 71 6 2007 1525 1534
-
(2007)
Mol Pharmacol
, vol.71
, Issue.6
, pp. 1525-1534
-
-
Marx, C.1
-
111
-
-
0028846193
-
Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
-
S.A. Onate Sequence and characterization of a coactivator for the steroid hormone receptor superfamily Science 270 5240 1995 1354 1357
-
(1995)
Science
, vol.270
, Issue.5240
, pp. 1354-1357
-
-
Onate, S.A.1
-
112
-
-
0029680381
-
Hybrid selection of transcribed sequences from microdissected DNA: Isolation of genes within amplified region at 20q11-q13.2 in breast cancer
-
X.Y. Guan Hybrid selection of transcribed sequences from microdissected DNA: isolation of genes within amplified region at 20q11-q13.2 in breast cancer Cancer Res 56 15 1996 3446 3450
-
(1996)
Cancer Res
, vol.56
, Issue.15
, pp. 3446-3450
-
-
Guan, X.Y.1
-
113
-
-
34250881447
-
Coregulators: From whence came these "master genes"
-
B.W. O'Malley Coregulators: from whence came these "master genes" Mol Endocrinol 21 5 2007 1009 1013
-
(2007)
Mol Endocrinol
, vol.21
, Issue.5
, pp. 1009-1013
-
-
O'Malley, B.W.1
-
114
-
-
0942290543
-
A methylation-mediator complex in hormone signaling
-
W. Xu A methylation-mediator complex in hormone signaling Genes Dev 18 2 2004 144 156
-
(2004)
Genes Dev
, vol.18
, Issue.2
, pp. 144-156
-
-
Xu, W.1
-
115
-
-
4944243842
-
Expression of SRC-1, AIB1, and PEA3 in HER2 mediated endocrine resistant breast cancer; A predictive role for SRC-1
-
F.J. Fleming Expression of SRC-1, AIB1, and PEA3 in HER2 mediated endocrine resistant breast cancer; a predictive role for SRC-1 J Clin Pathol 57 10 2004 1069 1074
-
(2004)
J Clin Pathol
, vol.57
, Issue.10
, pp. 1069-1074
-
-
Fleming, F.J.1
-
116
-
-
16844375445
-
Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer
-
E. Myers Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer Clin Cancer Res 11 6 2005 2111 2122
-
(2005)
Clin Cancer Res
, vol.11
, Issue.6
, pp. 2111-2122
-
-
Myers, E.1
-
117
-
-
34548252291
-
Nuclear receptor coregulators: Judges, juries, and executioners of cellular regulation
-
D.M. Lonard, and B.W. O'Malley Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation Mol Cell 27 5 2007 691 700
-
(2007)
Mol Cell
, vol.27
, Issue.5
, pp. 691-700
-
-
Lonard, D.M.1
O'Malley, B.W.2
-
118
-
-
8544284122
-
The nuclear receptor coactivator AIB1 mediates insulin-like growth factor I-induced phenotypic changes in human breast cancer cells
-
A. Oh The nuclear receptor coactivator AIB1 mediates insulin-like growth factor I-induced phenotypic changes in human breast cancer cells Cancer Res 64 22 2004 8299 8308
-
(2004)
Cancer Res
, vol.64
, Issue.22
, pp. 8299-8308
-
-
Oh, A.1
-
119
-
-
2942628182
-
ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance
-
M.C. Louie ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance Mol Cell Biol 24 12 2004 5157 5171
-
(2004)
Mol Cell Biol
, vol.24
, Issue.12
, pp. 5157-5171
-
-
Louie, M.C.1
-
120
-
-
4544314561
-
High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene
-
M.I. Torres-Arzayus High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene Cancer Cell 6 3 2004 263 274
-
(2004)
Cancer Cell
, vol.6
, Issue.3
, pp. 263-274
-
-
Torres-Arzayus, M.I.1
-
121
-
-
45549110356
-
The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice
-
M.P. Fereshteh The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice Cancer Res 68 10 2008 3697 3706
-
(2008)
Cancer Res
, vol.68
, Issue.10
, pp. 3697-3706
-
-
Fereshteh, M.P.1
-
122
-
-
52649149854
-
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression
-
L. Qin The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression Mol Cell Biol 28 19 2008 5937 5950
-
(2008)
Mol Cell Biol
, vol.28
, Issue.19
, pp. 5937-5950
-
-
Qin, L.1
-
123
-
-
82055185689
-
Small molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1
-
Y. Wang Small molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1 Mol Endocrinol 25 12 2011 2041 2053
-
(2011)
Mol Endocrinol
, vol.25
, Issue.12
, pp. 2041-2053
-
-
Wang, Y.1
-
124
-
-
30344477367
-
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
-
S. Minucci, and P.G. Pelicci Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer Nat Rev Cancer 6 1 2006 38 51
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.1
, pp. 38-51
-
-
Minucci, S.1
Pelicci, P.G.2
-
125
-
-
0242637101
-
Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity
-
C. Wang Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity J Biol Chem 276 21 2001 18375 18383
-
(2001)
J Biol Chem
, vol.276
, Issue.21
, pp. 18375-18383
-
-
Wang, C.1
-
126
-
-
33745658056
-
Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor
-
M.Y. Kim Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor Mol Endocrinol 20 7 2006 1479 1493
-
(2006)
Mol Endocrinol
, vol.20
, Issue.7
, pp. 1479-1493
-
-
Kim, M.Y.1
-
127
-
-
77956627130
-
Trichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein
-
S.H. Kim Trichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein Breast Cancer Res 12 2 2010 R22
-
(2010)
Breast Cancer Res
, vol.12
, Issue.2
, pp. 22
-
-
Kim, S.H.1
-
128
-
-
57749101152
-
Specific activity of class II histone deacetylases in human breast cancer cells
-
V. Duong Specific activity of class II histone deacetylases in human breast cancer cells Mol Cancer Res 6 12 2008 1908 1919
-
(2008)
Mol Cancer Res
, vol.6
, Issue.12
, pp. 1908-1919
-
-
Duong, V.1
-
129
-
-
41949118169
-
Histone deacetylase inhibitor SAHA induces ERalpha degradation in breast cancer MCF-7 cells by CHIP-mediated ubiquitin pathway and inhibits survival signaling
-
X. Yi Histone deacetylase inhibitor SAHA induces ERalpha degradation in breast cancer MCF-7 cells by CHIP-mediated ubiquitin pathway and inhibits survival signaling Biochem Pharmacol 75 9 2008 1697 1705
-
(2008)
Biochem Pharmacol
, vol.75
, Issue.9
, pp. 1697-1705
-
-
Yi, X.1
-
130
-
-
77955980628
-
Liposomes loaded with histone deacetylase inhibitors for breast cancer therapy
-
G. Urbinati Liposomes loaded with histone deacetylase inhibitors for breast cancer therapy Int J Pharm 397 1-2 2010 184 193
-
(2010)
Int J Pharm
, vol.397
, Issue.12
, pp. 184-193
-
-
Urbinati, G.1
-
131
-
-
69449093587
-
HDAC inhibitor-based therapies and haematological malignancy
-
L. Stimson HDAC inhibitor-based therapies and haematological malignancy Ann Oncol 20 8 2009 1293 1302
-
(2009)
Ann Oncol
, vol.20
, Issue.8
, pp. 1293-1302
-
-
Stimson, L.1
-
132
-
-
0034671304
-
Transcriptional activation of estrogen receptor alpha in human breast cancer cells by histone deacetylase inhibition
-
X. Yang Transcriptional activation of estrogen receptor alpha in human breast cancer cells by histone deacetylase inhibition Cancer Res 60 24 2000 6890 6894
-
(2000)
Cancer Res
, vol.60
, Issue.24
, pp. 6890-6894
-
-
Yang, X.1
-
133
-
-
0035477320
-
Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells
-
X. Yang Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells Cancer Res 61 19 2001 7025 7029
-
(2001)
Cancer Res
, vol.61
, Issue.19
, pp. 7025-7029
-
-
Yang, X.1
-
134
-
-
33847111684
-
Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation
-
Q. Zhou, P. Atadja, and N.E. Davidson Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation Cancer Biol Ther 6 1 2007 64 69
-
(2007)
Cancer Biol Ther
, vol.6
, Issue.1
, pp. 64-69
-
-
Zhou, Q.1
Atadja, P.2
Davidson, N.E.3
-
135
-
-
68949105725
-
Inhibition of histone deacetylase suppresses EGF signaling pathways by destabilizing EGFR mRNA in ER-negative human breast cancer cells
-
Q. Zhou, P.G. Shaw, and N.E. Davidson Inhibition of histone deacetylase suppresses EGF signaling pathways by destabilizing EGFR mRNA in ER-negative human breast cancer cells Breast Cancer Res Treat 117 2 2009 443 451
-
(2009)
Breast Cancer Res Treat
, vol.117
, Issue.2
, pp. 443-451
-
-
Zhou, Q.1
Shaw, P.G.2
Davidson, N.E.3
-
136
-
-
1642339046
-
The histone deacetylase inhibitor trichostatin A sensitizes estrogen receptor alpha-negative breast cancer cells to tamoxifen
-
E.R. Jang The histone deacetylase inhibitor trichostatin A sensitizes estrogen receptor alpha-negative breast cancer cells to tamoxifen Oncogene 23 9 2004 1724 1736
-
(2004)
Oncogene
, vol.23
, Issue.9
, pp. 1724-1736
-
-
Jang, E.R.1
-
137
-
-
2342528466
-
Histone deacetylase inhibition and estrogen receptor alpha levels modulate the transcriptional activity of partial antiestrogens
-
R. Margueron Histone deacetylase inhibition and estrogen receptor alpha levels modulate the transcriptional activity of partial antiestrogens J Mol Endocrinol 32 2 2004 583 594
-
(2004)
J Mol Endocrinol
, vol.32
, Issue.2
, pp. 583-594
-
-
Margueron, R.1
-
138
-
-
0036527775
-
Histone-deacetylase inhibitors: Novel drugs for the treatment of cancer
-
R.W. Johnstone Histone-deacetylase inhibitors: novel drugs for the treatment of cancer Nat Rev Drug Discov 1 4 2002 287 299
-
(2002)
Nat Rev Drug Discov
, vol.1
, Issue.4
, pp. 287-299
-
-
Johnstone, R.W.1
-
139
-
-
23644434852
-
Histone deacetylase inhibitors: Insights into mechanisms of lethality
-
R.R. Rosato, and S. Grant Histone deacetylase inhibitors: insights into mechanisms of lethality Expert Opin Ther Targets 9 4 2005 809 824
-
(2005)
Expert Opin Ther Targets
, vol.9
, Issue.4
, pp. 809-824
-
-
Rosato, R.R.1
Grant, S.2
-
140
-
-
77955643796
-
The clinical development of histone deacetylase inhibitors as targeted anticancer drugs
-
P.A. Marks The clinical development of histone deacetylase inhibitors as targeted anticancer drugs Expert Opin Investig Drugs 19 9 2010 1049 1066
-
(2010)
Expert Opin Investig Drugs
, vol.19
, Issue.9
, pp. 1049-1066
-
-
Marks, P.A.1
-
141
-
-
67349237892
-
Histone deacetylase inhibitor induced modulation of anti-estrogen therapy
-
S. Thomas, and P.N. Munster Histone deacetylase inhibitor induced modulation of anti-estrogen therapy Cancer Lett 280 2 2009 184 191
-
(2009)
Cancer Lett
, vol.280
, Issue.2
, pp. 184-191
-
-
Thomas, S.1
Munster, P.N.2
-
142
-
-
0029693220
-
The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation
-
C. Van Lint, S. Emiliani, and E. Verdin The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation Gene Expr 5 4-5 1996 245 253
-
(1996)
Gene Expr
, vol.5
, Issue.45
, pp. 245-253
-
-
Van Lint, C.1
Emiliani, S.2
Verdin, E.3
-
143
-
-
17744416444
-
Histone deacetylase inhibitor activates the WAF1/Cip1 gene promoter through the Sp1 sites
-
Y. Sowa Histone deacetylase inhibitor activates the WAF1/Cip1 gene promoter through the Sp1 sites Biochem Biophys Res Commun 241 1 1997 142 150
-
(1997)
Biochem Biophys Res Commun
, vol.241
, Issue.1
, pp. 142-150
-
-
Sowa, Y.1
-
144
-
-
0142182098
-
Oestrogen receptor alpha increases p21(WAF1/CIP1) gene expression and the antiproliferative activity of histone deacetylase inhibitors in human breast cancer cells
-
R. Margueron Oestrogen receptor alpha increases p21(WAF1/CIP1) gene expression and the antiproliferative activity of histone deacetylase inhibitors in human breast cancer cells J Endocrinol 179 1 2003 41 53
-
(2003)
J Endocrinol
, vol.179
, Issue.1
, pp. 41-53
-
-
Margueron, R.1
-
145
-
-
0035755974
-
Histone deacetylases and cancer: Causes and therapies
-
P. Marks Histone deacetylases and cancer: causes and therapies Nat Rev Cancer 1 3 2001 194 202
-
(2001)
Nat Rev Cancer
, vol.1
, Issue.3
, pp. 194-202
-
-
Marks, P.1
-
146
-
-
26044446524
-
Targeted histone deacetylase inhibition for cancer prevention and therapy
-
C. Palmieri, R.C. Coombes, and D.M. Vigushin Targeted histone deacetylase inhibition for cancer prevention and therapy Prog Drug Res 63 2005 147 181
-
(2005)
Prog Drug Res
, vol.63
, pp. 147-181
-
-
Palmieri, C.1
Coombes, R.C.2
Vigushin, D.M.3
-
147
-
-
33748451151
-
Anticancer activities of histone deacetylase inhibitors
-
J.E. Bolden, M.J. Peart, and R.W. Johnstone Anticancer activities of histone deacetylase inhibitors Nat Rev Drug Discov 5 9 2006 769 784
-
(2006)
Nat Rev Drug Discov
, vol.5
, Issue.9
, pp. 769-784
-
-
Bolden, J.E.1
Peart, M.J.2
Johnstone, R.W.3
-
148
-
-
21144444486
-
HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor
-
J.J. Kovacs HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor Mol Cell 18 5 2005 601 607
-
(2005)
Mol Cell
, vol.18
, Issue.5
, pp. 601-607
-
-
Kovacs, J.J.1
-
149
-
-
84857036295
-
A novel GRK2/HDAC6 interaction modulates cell spreading and motility
-
V. Lafarga A novel GRK2/HDAC6 interaction modulates cell spreading and motility Embo J 31 4 2011 856 869
-
(2011)
Embo J
, vol.31
, Issue.4
, pp. 856-869
-
-
Lafarga, V.1
-
150
-
-
0032907106
-
The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily
-
Z. Nawaz The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily Mol Cell Biol 19 2 1999 1182 1189
-
(1999)
Mol Cell Biol
, vol.19
, Issue.2
, pp. 1182-1189
-
-
Nawaz, Z.1
-
151
-
-
84857923196
-
Overexpression of ligase defective E6-associated protein, E6-AP, results in mammary tumorigenesis
-
S. Ramamoorthy Overexpression of ligase defective E6-associated protein, E6-AP, results in mammary tumorigenesis Breast Cancer Res Treat 132 1 2012 97 108
-
(2012)
Breast Cancer Res Treat
, vol.132
, Issue.1
, pp. 97-108
-
-
Ramamoorthy, S.1
-
152
-
-
47549090307
-
Regulation of estrogen rapid signaling through arginine methylation by PRMT1
-
M. Le Romancer Regulation of estrogen rapid signaling through arginine methylation by PRMT1 Mol Cell 31 2 2008 212 221
-
(2008)
Mol Cell
, vol.31
, Issue.2
, pp. 212-221
-
-
Le Romancer, M.1
-
153
-
-
33845345621
-
LKB1 is recruited to the p21/WAF1 promoter by p53 to mediate transcriptional activation
-
P.Y. Zeng, and S.L. Berger LKB1 is recruited to the p21/WAF1 promoter by p53 to mediate transcriptional activation Cancer Res 66 22 2006 10701 10708
-
(2006)
Cancer Res
, vol.66
, Issue.22
, pp. 10701-10708
-
-
Zeng, P.Y.1
Berger, S.L.2
-
154
-
-
33845332753
-
Enhanced expression of LKB1 in breast cancer cells attenuates angiogenesis, invasion, and metastatic potential
-
Z.G. Zhuang Enhanced expression of LKB1 in breast cancer cells attenuates angiogenesis, invasion, and metastatic potential Mol Cancer Res 4 11 2006 843 849
-
(2006)
Mol Cancer Res
, vol.4
, Issue.11
, pp. 843-849
-
-
Zhuang, Z.G.1
-
155
-
-
34648828532
-
AMP-activated/SNF1 protein kinases: Conserved guardians of cellular energy
-
D.G. Hardie AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy Nat Rev Mol Cell Biol 8 10 2007 774 785
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.10
, pp. 774-785
-
-
Hardie, D.G.1
-
156
-
-
66349089845
-
LKB1 catalytic activity contributes to estrogen receptor alpha signaling
-
S. Nath-Sain, and P.A. Marignani LKB1 catalytic activity contributes to estrogen receptor alpha signaling Mol Biol Cell 20 11 2009 2785 2795
-
(2009)
Mol Biol Cell
, vol.20
, Issue.11
, pp. 2785-2795
-
-
Nath-Sain, S.1
Marignani, P.A.2
-
157
-
-
81255158970
-
LKB1 expression is inhibited by estradiol-17beta in MCF-7 cells
-
K.A. Brown LKB1 expression is inhibited by estradiol-17beta in MCF-7 cells J Steroid Biochem Mol Biol 127 3-5 2011 439 443
-
(2011)
J Steroid Biochem Mol Biol
, vol.127
, Issue.35
, pp. 439-443
-
-
Brown, K.A.1
-
158
-
-
84855986981
-
Liver kinase B1 expression (LKB1) is repressed by estrogen receptor alpha (ERalpha) in MCF-7 human breast cancer cells
-
K. Linher-Melville, S. Zantinge, and G. Singh Liver kinase B1 expression (LKB1) is repressed by estrogen receptor alpha (ERalpha) in MCF-7 human breast cancer cells Biochem Biophys Res Commun 417 3 2012 1063 1068
-
(2012)
Biochem Biophys Res Commun
, vol.417
, Issue.3
, pp. 1063-1068
-
-
Linher-Melville, K.1
Zantinge, S.2
Singh, G.3
-
159
-
-
77956150294
-
Metformin inhibits aromatase expression in human breast adipose stromal cells via stimulation of AMP-activated protein kinase
-
K.A. Brown Metformin inhibits aromatase expression in human breast adipose stromal cells via stimulation of AMP-activated protein kinase Breast Cancer Res Treat 123 2 2010 591 596
-
(2010)
Breast Cancer Res Treat
, vol.123
, Issue.2
, pp. 591-596
-
-
Brown, K.A.1
-
160
-
-
68049137624
-
LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cells
-
L. Taliaferro-Smith LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cells Oncogene 28 29 2009 2621 2633
-
(2009)
Oncogene
, vol.28
, Issue.29
, pp. 2621-2633
-
-
Taliaferro-Smith, L.1
-
161
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
B.D. Manning, and L.C. Cantley AKT/PKB signaling: navigating downstream Cell 129 7 2007 1261 1274
-
(2007)
Cell
, vol.129
, Issue.7
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
162
-
-
36249027472
-
Inhibition of estradiol receptor/Src association and cell growth by an estradiol receptor alpha tyrosine-phosphorylated peptide
-
L. Varricchio Inhibition of estradiol receptor/Src association and cell growth by an estradiol receptor alpha tyrosine-phosphorylated peptide Mol Cancer Res 5 11 2007 1213 1221
-
(2007)
Mol Cancer Res
, vol.5
, Issue.11
, pp. 1213-1221
-
-
Varricchio, L.1
-
163
-
-
33745402375
-
Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells
-
S. Hiscox Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells Breast Cancer Res Treat 97 3 2006 263 274
-
(2006)
Breast Cancer Res Treat
, vol.97
, Issue.3
, pp. 263-274
-
-
Hiscox, S.1
-
164
-
-
67649311599
-
Latent bone metastasis in breast cancer tied to Src-dependent survival signals
-
X.H. Zhang Latent bone metastasis in breast cancer tied to Src-dependent survival signals Cancer Cell 16 1 2009 67 78
-
(2009)
Cancer Cell
, vol.16
, Issue.1
, pp. 67-78
-
-
Zhang, X.H.1
-
165
-
-
33846235881
-
Cooperative action of tamoxifen and c-Src inhibition in preventing the growth of estrogen receptor-positive human breast cancer cells
-
M.H. Herynk Cooperative action of tamoxifen and c-Src inhibition in preventing the growth of estrogen receptor-positive human breast cancer cells Mol Cancer Ther 5 12 2006 3023 3031
-
(2006)
Mol Cancer Ther
, vol.5
, Issue.12
, pp. 3023-3031
-
-
Herynk, M.H.1
-
166
-
-
33846870586
-
Src as a therapeutic target in anti-hormone/anti-growth factor-resistant breast cancer
-
S. Hiscox Src as a therapeutic target in anti-hormone/anti-growth factor-resistant breast cancer Endocr Relat Cancer 13 Suppl. 1 2006 S53 S59
-
(2006)
Endocr Relat Cancer
, vol.13
, Issue.SUPPL. 1
-
-
Hiscox, S.1
-
167
-
-
84860390293
-
Estrogen receptor beta represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: Implications for tamoxifen sensitivity
-
K. Lindberg Estrogen receptor beta represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity Breast Cancer Res 13 2 2011 R43
-
(2011)
Breast Cancer Res
, vol.13
, Issue.2
, pp. 43
-
-
Lindberg, K.1
-
168
-
-
79953298958
-
Next-generation mTOR inhibitors in clinical oncology: How pathway complexity informs therapeutic strategy
-
S.A. Wander, B.T. Hennessy, and J.M. Slingerland Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy J Clin Invest 121 4 2011 1231 1241
-
(2011)
J Clin Invest
, vol.121
, Issue.4
, pp. 1231-1241
-
-
Wander, S.A.1
Hennessy, B.T.2
Slingerland, J.M.3
-
169
-
-
37549024511
-
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
-
C. Blenkiron MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype Genome Biol 8 10 2007 R214
-
(2007)
Genome Biol
, vol.8
, Issue.10
, pp. 214
-
-
Blenkiron, C.1
-
170
-
-
34250843675
-
The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines
-
B.D. Adams, H. Furneaux, and B.A. White The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines Mol Endocrinol 21 5 2007 1132 1147
-
(2007)
Mol Endocrinol
, vol.21
, Issue.5
, pp. 1132-1147
-
-
Adams, B.D.1
Furneaux, H.2
White, B.A.3
-
171
-
-
84856005898
-
Induction of cell proliferation and survival genes by estradiol-repressed microRNAs in breast cancer cells
-
X. Yu Induction of cell proliferation and survival genes by estradiol-repressed microRNAs in breast cancer cells BMC Cancer 12 2012 29
-
(2012)
BMC Cancer
, vol.12
, pp. 29
-
-
Yu, X.1
-
172
-
-
84860386584
-
MiRNAs and estrogen action
-
C.M. Klinge MiRNAs and estrogen action Trends Endocrinol Metab 23 5 2012 223 233
-
(2012)
Trends Endocrinol Metab
, vol.23
, Issue.5
, pp. 223-233
-
-
Klinge, C.M.1
-
173
-
-
33750328319
-
HOXB7, a homeodomain protein, is overexpressed in breast cancer and confers epithelial-mesenchymal transition
-
X. Wu HOXB7, a homeodomain protein, is overexpressed in breast cancer and confers epithelial-mesenchymal transition Cancer Res 66 19 2006 9527 9534
-
(2006)
Cancer Res
, vol.66
, Issue.19
, pp. 9527-9534
-
-
Wu, X.1
-
174
-
-
84863115448
-
The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway
-
K. Jin The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway Proc Natl Acad Sci USA 109 8 2012 2736 2741
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.8
, pp. 2736-2741
-
-
Jin, K.1
-
175
-
-
84863393402
-
Transducin-like enhancer protein 1 mediates estrogen receptor binding and transcriptional activity in breast cancer cells
-
K.A. Holmes Transducin-like enhancer protein 1 mediates estrogen receptor binding and transcriptional activity in breast cancer cells Proc Natl Acad Sci USA 109 8 2012 2748 2753
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.8
, pp. 2748-2753
-
-
Holmes, K.A.1
-
176
-
-
57349113761
-
Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen
-
A. Hurtado Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen Nature 456 7222 2008 663 666
-
(2008)
Nature
, vol.456
, Issue.7222
, pp. 663-666
-
-
Hurtado, A.1
-
177
-
-
78651250284
-
FOXA1 is a key determinant of estrogen receptor function and endocrine response
-
A. Hurtado FOXA1 is a key determinant of estrogen receptor function and endocrine response Nat Genet 43 1 2011 27 33
-
(2011)
Nat Genet
, vol.43
, Issue.1
, pp. 27-33
-
-
Hurtado, A.1
-
178
-
-
40849085514
-
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription
-
M. Lupien FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription Cell 132 6 2008 958 970
-
(2008)
Cell
, vol.132
, Issue.6
, pp. 958-970
-
-
Lupien, M.1
-
179
-
-
3042822267
-
Cancer and the chemokine network
-
F. Balkwill Cancer and the chemokine network Nat Rev Cancer 4 7 2004 540 550
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.7
, pp. 540-550
-
-
Balkwill, F.1
-
180
-
-
0037448628
-
IL-8 expression and its possible relationship with estrogen-receptor- negative status of breast cancer cells
-
A. Freund IL-8 expression and its possible relationship with estrogen-receptor-negative status of breast cancer cells Oncogene 22 2 2003 256 265
-
(2003)
Oncogene
, vol.22
, Issue.2
, pp. 256-265
-
-
Freund, A.1
-
181
-
-
36148979810
-
CXC chemokines located in the 4q21 region are up-regulated in breast cancer
-
I. Bieche CXC chemokines located in the 4q21 region are up-regulated in breast cancer Endocr Relat Cancer 14 4 2007 1039 1052
-
(2007)
Endocr Relat Cancer
, vol.14
, Issue.4
, pp. 1039-1052
-
-
Bieche, I.1
-
182
-
-
34248148710
-
Oestrogen receptor negative breast cancers exhibit high cytokine content
-
C. Chavey Oestrogen receptor negative breast cancers exhibit high cytokine content Breast Cancer Res 9 1 2007 R15
-
(2007)
Breast Cancer Res
, vol.9
, Issue.1
, pp. 15
-
-
Chavey, C.1
-
183
-
-
77949329326
-
Chemokines and chemokine receptors: New insights into cancer-related inflammation
-
G. Lazennec, and A. Richmond Chemokines and chemokine receptors: new insights into cancer-related inflammation Trends Mol Med 16 3 2010 133 144
-
(2010)
Trends Mol Med
, vol.16
, Issue.3
, pp. 133-144
-
-
Lazennec, G.1
Richmond, A.2
-
184
-
-
0038636392
-
Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells
-
J.M. Hall, and K.S. Korach Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells Mol Endocrinol 17 5 2003 792 803
-
(2003)
Mol Endocrinol
, vol.17
, Issue.5
, pp. 792-803
-
-
Hall, J.M.1
Korach, K.S.2
-
185
-
-
67651005771
-
Positive feedback activation of estrogen receptors by the CXCL12-CXCR4 pathway
-
K. Sauve Positive feedback activation of estrogen receptors by the CXCL12-CXCR4 pathway Cancer Res 69 14 2009 5793 5800
-
(2009)
Cancer Res
, vol.69
, Issue.14
, pp. 5793-5800
-
-
Sauve, K.1
-
186
-
-
84856091317
-
Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer
-
D.R. Robinson Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer Nat Med 17 12 2011 1646 1651
-
(2011)
Nat Med
, vol.17
, Issue.12
, pp. 1646-1651
-
-
Robinson, D.R.1
-
187
-
-
84860117771
-
Detection of redundant fusion transcripts as biomarkers or disease-specific therapeutic targets in breast cancer
-
Y.W. Asmann Detection of redundant fusion transcripts as biomarkers or disease-specific therapeutic targets in breast cancer Cancer Res 72 8 2012 1921 1928
-
(2012)
Cancer Res
, vol.72
, Issue.8
, pp. 1921-1928
-
-
Asmann, Y.W.1
-
188
-
-
50249175241
-
Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential?
-
L. Nolan Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential? Br J Cancer 99 5 2008 689 694
-
(2008)
Br J Cancer
, vol.99
, Issue.5
, pp. 689-694
-
-
Nolan, L.1
-
189
-
-
59349106138
-
Timing is everything: Order of administration of 5-aza 2′ deoxycytidine, trichostatin A and tamoxifen changes estrogen receptor mRNA expression and cell sensitivity
-
C.L. Hostetter, L.A. Licata, and J.C. Keen Timing is everything: order of administration of 5-aza 2′ deoxycytidine, trichostatin A and tamoxifen changes estrogen receptor mRNA expression and cell sensitivity Cancer Lett 275 2 2009 178 184
-
(2009)
Cancer Lett
, vol.275
, Issue.2
, pp. 178-184
-
-
Hostetter, C.L.1
Licata, L.A.2
Keen, J.C.3
-
190
-
-
79958084461
-
A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer
-
P.N. Munster A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer Br J Cancer 104 12 2011 1828 1835
-
(2011)
Br J Cancer
, vol.104
, Issue.12
, pp. 1828-1835
-
-
Munster, P.N.1
-
191
-
-
58249122591
-
Tosylcyclonovobiocic acids promote cleavage of the hsp90-associated cochaperone p23
-
C. Radanyi Tosylcyclonovobiocic acids promote cleavage of the hsp90-associated cochaperone p23 Biochem Biophys Res Commun 379 2 2009 514 518
-
(2009)
Biochem Biophys Res Commun
, vol.379
, Issue.2
, pp. 514-518
-
-
Radanyi, C.1
-
192
-
-
84988539832
-
Liposomal trichostatin A: Therapeutic potential in hormone-dependent and -independent breast cancer xenograft models
-
G. Urbinati Liposomal trichostatin A: therapeutic potential in hormone-dependent and -independent breast cancer xenograft models Horm Mol Biol Clin Invest 6 2 2011 215 225
-
(2011)
Horm Mol Biol Clin Invest
, vol.6
, Issue.2
, pp. 215-225
-
-
Urbinati, G.1
-
193
-
-
18244373706
-
Enhanced pharmacodynamic and antitumor properties of a histone deacetylase inhibitor encapsulated in liposomes or ErbB2-targeted immunoliposomes
-
D.C. Drummond Enhanced pharmacodynamic and antitumor properties of a histone deacetylase inhibitor encapsulated in liposomes or ErbB2-targeted immunoliposomes Clin Cancer Res 11 9 2005 3392 3401
-
(2005)
Clin Cancer Res
, vol.11
, Issue.9
, pp. 3392-3401
-
-
Drummond, D.C.1
-
194
-
-
34249327294
-
Targeted pharmaceutical nanocarriers for cancer therapy and imaging
-
V.P. Torchilin Targeted pharmaceutical nanocarriers for cancer therapy and imaging Aaps J 9 2 2007 E128 E147
-
(2007)
Aaps J
, vol.9
, Issue.2
-
-
Torchilin, V.P.1
-
195
-
-
62549090127
-
CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts
-
E. Marangoni CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts Br J Cancer 100 6 2009 918 922
-
(2009)
Br J Cancer
, vol.100
, Issue.6
, pp. 918-922
-
-
Marangoni, E.1
-
196
-
-
33745174538
-
Heat shock protein-90 inhibitors: A chronicle from geldanamycin to today's agents
-
G. Chiosis, E. Caldas Lopes, and D. Solit Heat shock protein-90 inhibitors: a chronicle from geldanamycin to today's agents Curr Opin Investig Drugs 7 6 2006 534 541
-
(2006)
Curr Opin Investig Drugs
, vol.7
, Issue.6
, pp. 534-541
-
-
Chiosis, G.1
Caldas Lopes, E.2
Solit, D.3
-
197
-
-
79955026617
-
Discovery and biological activity of 6BrCaQ as an inhibitor of the Hsp90 protein folding machinery
-
D. Audisio Discovery and biological activity of 6BrCaQ as an inhibitor of the Hsp90 protein folding machinery ChemMedChem 6 5 2011 804 815
-
(2011)
ChemMedChem
, vol.6
, Issue.5
, pp. 804-815
-
-
Audisio, D.1
-
198
-
-
79958171071
-
Engineering an antibiotic to fight cancer: Optimization of the novobiocin scaffold to produce anti-proliferative agents
-
H. Zhao Engineering an antibiotic to fight cancer: optimization of the novobiocin scaffold to produce anti-proliferative agents J Med Chem 54 11 2011 3839 3853
-
(2011)
J Med Chem
, vol.54
, Issue.11
, pp. 3839-3853
-
-
Zhao, H.1
-
199
-
-
33751231430
-
Improved anti-tumoral capacity of mixed and pure anti-oestrogens in breast cancer cell xenografts after their administration by entrapment in colloidal nanosystems
-
J.M. Renoir Improved anti-tumoral capacity of mixed and pure anti-oestrogens in breast cancer cell xenografts after their administration by
-
(2006)
J Steroid Biochem Mol Biol
, vol.102
, Issue.15
, pp. 114-127
-
-
Renoir, J.M.1
-
200
-
-
0042934090
-
Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression
-
W.R. Harrington Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression Mol Cell Endocrinol 206 1-2 2003 13 22
-
(2003)
Mol Cell Endocrinol
, vol.206
, Issue.12
, pp. 13-22
-
-
Harrington, W.R.1
|