-
1
-
-
0027358723
-
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
-
DOI 10.1016/0092-8674(93)90384-3
-
Scheffner M, Huibregtse JM, Vierstra RD, Howley PM (1993) The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75(3):495-505 (Pubitemid 23335075)
-
(1993)
Cell
, vol.75
, Issue.3
, pp. 495-505
-
-
Scheffner, M.1
Huibregtse, J.M.2
Vierstra, R.D.3
Howley, P.M.4
-
2
-
-
0032907106
-
The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily
-
Nawaz Z, Lonard DM, Smith CL, Lev-Lehman E, Tsai SY, Tsai MJ, O'Malley BW (1999) The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily. Mol Cell Biol 19(2):1182-1189 (Pubitemid 29046860)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.2
, pp. 1182-1189
-
-
Nawaz, Z.1
Lonard, D.M.2
Smith, C.L.3
Lev-Lehman, E.4
Tsai, S.Y.5
Tsai, M.-J.6
O'Malley, B.W.7
-
3
-
-
15444368956
-
Decreased expression of E6-associated protein in breast and prostate carcinomas
-
DOI 10.1210/en.2004-1198
-
Gao X, Mohsin SK, Gatalica Z, Fu G, Sharma P, Nawaz Z (2005) Decreased expression of e6-associated protein in breast and prostate carcinomas. Endocrinology 146(4):1707-1712 (Pubitemid 40396878)
-
(2005)
Endocrinology
, vol.146
, Issue.4
, pp. 1707-1712
-
-
Gao, X.1
Mohsin, S.K.2
Gatalica, Z.3
Fu, G.4
Sharma, P.5
Nawaz, Z.6
-
4
-
-
78049325347
-
Isoform-specific degradation of PR-B by E6-AP is critical for normal mammary gland development
-
doi:10.1210/me.2010-0116
-
Ramamoorthy S, Dhananjayan SC, Demayo FJ, Nawaz Z (2010) Isoform-specific degradation of PR-B by E6-AP is critical for normal mammary gland development. Mol Endocrinol 24(11):2099-2113. doi:10.1210/me.2010-0116
-
(2010)
Mol Endocrinol
, vol.24
, Issue.11
, pp. 2099-2113
-
-
Ramamoorthy, S.1
Dhananjayan, S.C.2
Demayo, F.J.3
Nawaz, Z.4
-
5
-
-
33344469819
-
Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland
-
DOI 10.1210/me.2005-0110
-
Khan OY, Fu G, Ismail A, Srinivasan S, Cao X, Tu Y, Lu S, Nawaz Z (2006) Multifunction steroid receptor coactivator, E6-associated protein, is involved in development of the prostate gland. Mol Endocrinol 20(3):544-559 (Pubitemid 43291207)
-
(2006)
Molecular Endocrinology
, vol.20
, Issue.3
, pp. 544-559
-
-
Khan, O.Y.1
Fu, G.2
Ismail, A.3
Srinivasan, S.4
Cao, X.5
Tu, Y.6
Lu, S.7
Nawaz, Z.8
-
6
-
-
0027169680
-
Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins
-
Huibregtse JM, Scheffner M, Howley PM (1993) Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins. Mol Cell Biol 13(8):4918-4927 (Pubitemid 23220397)
-
(1993)
Molecular and Cellular Biology
, vol.13
, Issue.8
, pp. 4918-4927
-
-
Huibregtse, J.M.1
Scheffner, M.2
Howley, P.M.3
-
7
-
-
0028907874
-
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
-
Huibregtse JM, Scheffner M, Beaudenon S, Howley PM (1995) A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc Natl Acad Sci USA 92(7):2563-2567
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.7
, pp. 2563-2567
-
-
Huibregtse, J.M.1
Scheffner, M.2
Beaudenon, S.3
Howley, P.M.4
-
8
-
-
0028907874
-
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
-
Huibregtse JM, Scheffner M, Beaudenon S, Howley PM (1995) A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc Natl Acad Sci USA 92(11):5249
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.11
, pp. 5249
-
-
Huibregtse, J.M.1
Scheffner, M.2
Beaudenon, S.3
Howley, P.M.4
-
9
-
-
0030908874
-
Physical interaction between specific E2 and hect E3 enzymes determines functional cooperativity
-
DOI 10.1074/jbc.272.21.13548
-
Kumar S, Kao WH, Howley PM (1997) Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity. J Biol Chem 272(21):13548-13554 (Pubitemid 27224784)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.21
, pp. 13548-13554
-
-
Kumar, S.1
Kao, W.H.2
Howley, P.M.3
-
10
-
-
52949111533
-
Minireview: Nuclear receptors and breast cancer
-
doi:10.1210/me.2007-0421
-
Conzen SD (2008) Minireview: nuclear receptors and breast cancer. Mol Endocrinol 22(10):2215-2228. doi:10.1210/me.2007-0421
-
(2008)
Mol Endocrinol
, vol.22
, Issue.10
, pp. 2215-2228
-
-
Conzen, S.D.1
-
11
-
-
15544376261
-
Lessons in estrogen biology from knockout and transgenic animals
-
DOI 10.1146/annurev.physiol.67.040403.115914
-
Hewitt SC, Harrell JC, Korach KS (2005) Lessons in estrogen biology from knockout and transgenic animals. Annu Rev Physiol 67:285-308. doi:10.1146/annurev.physiol.67.040403.115914 (Pubitemid 40404493)
-
(2005)
Annual Review of Physiology
, vol.67
, pp. 285-308
-
-
Hewitt, S.C.1
Harrell, J.C.2
Korach, K.S.3
-
12
-
-
0022922715
-
Cloning of the human oestrogen receptor cDNA
-
DOI 10.1016/0022-4731(86)90035-X
-
Green S, Walter P, Greene G, Krust A, Goffin C, Jensen E, Scrace G, Waterfield M, Chambon P (1986) Cloning of the human oestrogen receptor cDNA. J Steroid Biochem 24(1):77-83 (Pubitemid 16047760)
-
(1986)
Journal of Steroid Biochemistry
, vol.24
, Issue.1
, pp. 77-83
-
-
Green, S.1
Walter, P.2
Greene, G.3
-
13
-
-
0006965816
-
Cloning of the chicken progesterone receptor
-
DOI 10.1073/pnas.83.15.5424
-
Jeltsch JM, Krozowski Z, Quirin-Stricker C, Gronemeyer H, Simpson RJ, Garnier JM, Krust A, Jacob F, Chambon P (1986) Cloning of the chicken progesterone receptor. Proc Natl Acad Sci USA 83(15):5424-5428 (Pubitemid 16001235)
-
(1986)
Proceedings of the National Academy of Sciences of the United States of America
, vol.83
, Issue.15
, pp. 5424-5428
-
-
Jeltsch, J.M.1
Krozowski, Z.2
Quirin-Stricker, C.3
-
14
-
-
0036129575
-
Steroid receptors in human breast tumorigenesis and breast cancer progression
-
DOI 10.1016/S0753-3322(01)00157-3
-
Murphy LC, Watson P (2002) Steroid receptors in human breast tumorigenesis and breast cancer progression. Biomed Pharmacother 56(2):65-77 (Pubitemid 34241560)
-
(2002)
Biomedicine and Pharmacotherapy
, vol.56
, Issue.2
, pp. 65-77
-
-
Murphy, L.C.1
Watson, P.2
-
15
-
-
21044455045
-
Mammary epithelial cell transformation: Insights from cell culture and mouse models
-
DOI 10.1186/bcr1275
-
Dimri G, Band H, Band V (2005) Mammary epithelial cell transformation: insights from cell culture and mouse models. Breast Cancer Res 7(4):171-179. doi:10.1186/bcr1275 (Pubitemid 40872783)
-
(2005)
Breast Cancer Research
, vol.7
, Issue.4
, pp. 171-179
-
-
Dimri, G.1
Band, H.2
Band, V.3
-
16
-
-
0019840727
-
Correlation of primary breast cancer histopathology and estrogen receptor content
-
Fisher ER, Osborne CK, McGuire WL, Redmond C, Knight WA 3rd, Fisher B, Bannayan G, Walder A, Gregory EJ, Jacobsen A, Queen DM, Bennett DE, Ford HC (1981) Correlation of primary breast cancer histopathology and estrogen receptor content. Breast Cancer Res Treat 1(1):37-41 (Pubitemid 12179413)
-
(1981)
Breast Cancer Research and Treatment
, vol.1
, Issue.1
, pp. 37-41
-
-
Fisher, E.R.1
Kent, O.C.2
McGuire, W.L.3
-
17
-
-
38749087231
-
Activation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha-negative and ERalpha-positive mammary preneoplasia and cancer
-
DOI 10.1038/sj.onc.1210674, PII 1210674
-
Jones LP, Tilli MT, Assefnia S, Torre K, Halama ED, Parrish A, Rosen EM, Furth PA (2008) Activation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha-negative and ERalpha-positive mammary preneoplasia and cancer. Oncogene 27(6):794-802. doi:10.1038/sj.onc. 1210674 (Pubitemid 351186312)
-
(2008)
Oncogene
, vol.27
, Issue.6
, pp. 794-802
-
-
Jones, L.P.1
Tilli, M.T.2
Assefnia, S.3
Torre, K.4
Halama, E.D.5
Parrish, A.6
Rosen, E.M.7
Furth, P.A.8
-
18
-
-
34548863946
-
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
-
doi:10.1186/gb-2007-8-5-r76
-
Herschkowitz JI, Simin K, Weigman VJ, Mikaelian I, Usary J, Hu Z, Rasmussen KE, Jones LP, Assefnia S, Chandrasekharan S, Backlund MG, Yin Y, Khramtsov AI, Bastein R, Quackenbush J, Glazer RI, Brown PH, Green JE, Kopelovich L, Furth PA, Palazzo JP, Olopade OI, Bernard PS, Churchill GA, Van Dyke T, Perou CM (2007) Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol 8(5):R76. doi:10.1186/gb-2007-8-5-r76
-
(2007)
Genome Biol
, vol.8
, Issue.5
-
-
Herschkowitz, J.I.1
Simin, K.2
Weigman, V.J.3
Mikaelian, I.4
Usary, J.5
Hu, Z.6
Rasmussen, K.E.7
Jones, L.P.8
Assefnia, S.9
Chandrasekharan, S.10
Backlund, M.G.11
Yin, Y.12
Khramtsov, A.I.13
Bastein, R.14
Quackenbush, J.15
Glazer, R.I.16
Brown, P.H.17
Green, J.E.18
Kopelovich, L.19
Furth, P.A.20
Palazzo, J.P.21
Olopade, O.I.22
Bernard, P.S.23
Churchill, G.A.24
Van Dyke, T.25
Perou, C.M.26
more..
-
19
-
-
0017700706
-
Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer
-
Knight WA, Livingston RB, Gregory EJ, McGuire WL (1977) Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer. Cancer Res 37(12):4669-4671 (Pubitemid 8239679)
-
(1977)
Cancer Research
, vol.37
, Issue.12
, pp. 4669-4671
-
-
Knight III, W.A.1
Livingston, R.B.2
Gregory, E.J.3
McGuire, W.L.4
-
20
-
-
0019763016
-
Estrogen receptor, a marker for human breast cancer differentiation and patient prognosis
-
Osborne CK, Fisher E, Redmond C, Knight WA, Yochmowitz MG, McGuire WL (1981) Estrogen receptor, a marker for human breast cancer differentiation and patient prognosis. Adv Exp Med Biol 138:377-385
-
(1981)
Adv Exp Med Biol
, vol.138
, pp. 377-385
-
-
Osborne, C.K.1
Fisher, E.2
Redmond, C.3
Knight, W.A.4
Yochmowitz, M.G.5
McGuire, W.L.6
-
21
-
-
57149143868
-
Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions
-
doi:10.1210/er.2008-0022
-
Kleinberg DL, Wood TL, Furth PA, Lee AV (2009) Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions. Endocr Rev 30(1):51-74. doi:10.1210/er.2008- 0022
-
(2009)
Endocr Rev
, vol.30
, Issue.1
, pp. 51-74
-
-
Kleinberg, D.L.1
Wood, T.L.2
Furth, P.A.3
Lee, A.V.4
-
22
-
-
0035995599
-
Progesterone's role in mammary gland development and tumorigenesis as disclosed by experimental mouse genetics
-
DOI 10.1186/bcr451
-
Soyal S, Ismail PM, Li J, Mulac-Jericevic B, Conneely OM, Lydon JP (2002) Progesterone's role in mammary gland development and tumorigenesis as disclosed by experimental mouse genetics. Breast Cancer Res 4(5):191-196 (Pubitemid 34918997)
-
(2002)
Breast Cancer Research
, vol.4
, Issue.5
, pp. 191-196
-
-
Soyal, S.1
Ismail, P.M.2
Li, J.3
Mulac-Jericevic, B.4
Conneely, O.M.5
Lydon, J.P.6
-
23
-
-
0019198985
-
The value of estrogen and progesterone receptors in the treatment of breast cancer
-
Osborne CK, Yochmowitz MG, Knight WA 3rd, McGuire WL (1980) The value of estrogen and progesterone receptors in the treatment of breast cancer. Cancer 46(12 Suppl):2884-2888 (Pubitemid 11205652)
-
(1980)
Cancer
, vol.46
, Issue.12 SUPPL.
, pp. 2884-2888
-
-
Osborne, C.K.1
Yochmowitz, M.G.2
Knight III, W.A.3
McGuire, W.L.4
-
25
-
-
0142182119
-
Introduction of Estrogen Receptor-alpha into the tTA/TAg Conditional Mouse Model Precipitates the Development of Estrogen-Responsive Mammary Adenocarcinoma
-
Tilli MT, Frech MS, Steed ME, Hruska KS, Johnson MD, Flaws JA, Furth PA (2003) Introduction of estrogen receptor-alpha into the tTA/TAg conditional mouse model precipitates the development of estrogen-responsive mammary adenocarcinoma. Am J Pathol 163(5):1713-1719 (Pubitemid 37310001)
-
(2003)
American Journal of Pathology
, vol.163
, Issue.5
, pp. 1713-1719
-
-
Tilli, M.T.1
Frech, M.S.2
Steed, M.E.3
Hruska, K.S.4
Johnson, M.D.5
Flaws, J.A.6
Furth, P.A.7
-
26
-
-
33748069145
-
Signalling pathways implicated in early mammary gland morphogenesis and breast cancer
-
doi:10.1371/journal.pgen.0020112
-
Howard B, Ashworth A (2006) Signalling pathways implicated in early mammary gland morphogenesis and breast cancer. PLoS Genet 2(8):e112. doi:10.1371/journal.pgen.0020112
-
(2006)
PLoS Genet
, vol.2
, Issue.8
-
-
Howard, B.1
Ashworth, A.2
-
27
-
-
0345859565
-
The roles of sex steroid receptor coregulators in cancer
-
Gao X, Loggie BW, Nawaz Z (2002) The roles of sex steroid receptor coregulators in cancer. Mol Cancer 1:7
-
(2002)
Mol Cancer
, vol.1
, pp. 7
-
-
Gao, X.1
Loggie, B.W.2
Nawaz, Z.3
-
28
-
-
0033765996
-
The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis
-
Sivaraman L, Nawaz Z, Medina D, Conneely OM, O'Malley BW (2000) The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis. Breast Cancer Res Treat 62(3):185-195
-
(2000)
Breast Cancer Res Treat
, vol.62
, Issue.3
, pp. 185-195
-
-
Sivaraman, L.1
Nawaz, Z.2
Medina, D.3
Conneely, O.M.4
O'Malley, B.W.5
-
29
-
-
33749346301
-
Modification of proteins by ubiquitin and ubiquitin-like proteins
-
doi:10.1146/annurev.cellbio.22.010605.093503
-
Kerscher O, Felberbaum R, Hochstrasser M (2006) Modification of proteins by ubiquitin and ubiquitin-like proteins. Annu Rev Cell Dev Biol 22:159-180. doi:10.1146/annurev.cellbio.22.010605.093503
-
(2006)
Annu Rev Cell Dev Biol
, vol.22
, pp. 159-180
-
-
Kerscher, O.1
Felberbaum, R.2
Hochstrasser, M.3
-
30
-
-
0348134742
-
Mono- versus Polyubiquitination: Differential Control of p53 Fate by Mdm2
-
DOI 10.1126/science.1091362
-
Li M, Brooks CL, Wu-Baer F, Chen D, Baer R, Gu W (2003) Mono- versus polyubiquitination: differential control of p53 fate by Mdm2. Science 302(5652):1972-1975 (Pubitemid 37523506)
-
(2003)
Science
, vol.302
, Issue.5652
, pp. 1972-1975
-
-
Li, M.1
Brooks, C.L.2
Wu-Baer, F.3
Chen, D.4
Baer, R.5
Gu, W.6
-
32
-
-
2342447397
-
The ubiquitin ligase COP1 is a critical negative regulator of p53
-
DOI 10.1038/nature02514
-
Dornan D, Wertz I, Shimizu H, Arnott D, Frantz GD, Dowd P, O'Rourke K, Koeppen H, Dixit VM (2004) The ubiquitin ligase COP1 is a critical negative regulator of p53. Nature 429(6987):86-92 (Pubitemid 38620556)
-
(2004)
Nature
, vol.429
, Issue.6987
, pp. 86-92
-
-
Dornan, D.1
Wertz, I.2
Shimizu, H.3
Arnott, D.4
Frantz, G.D.5
Dowd, P.6
O'Rourke, K.7
Koeppen, H.8
Dixit, V.M.9
-
33
-
-
0037294984
-
Requirement of E6AP and the features of human papillomavirus E6 necessary to support degradation of p53
-
DOI 10.1016/S0042-6822(02)00012-0, PII S0042682202000120
-
Cooper B, Schneider S, Bohl J, Jiang Y, Beaudet A, Vande Pol S (2003) Requirement of E6AP and the features of human papillomavirus E6 necessary to support degradation of p53. Virology 306(1):87-99 (Pubitemid 36293399)
-
(2003)
Virology
, vol.306
, Issue.1
, pp. 87-99
-
-
Cooper, B.1
Schneider, S.2
Bohl, J.3
Jiang, Y.-H.4
Beaudet, A.5
Vande, P.S.6
-
34
-
-
0033967491
-
Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome
-
DOI 10.1073/pnas.97.3.1032
-
Lange CA, Shen T, Horwitz KB (2000) Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome. Proc Natl Acad Sci USA 97(3):1032-1037 (Pubitemid 30080807)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.3
, pp. 1032-1037
-
-
Lange, C.A.1
Shen, T.2
Horwitz, K.B.3
-
35
-
-
0033514930
-
Proteasome-dependent degradation of the human estrogen receptor
-
DOI 10.1073/pnas.96.5.1858
-
Nawaz Z, Lonard DM, Dennis AP, Smith CL, O'Malley BW (1999) Proteasome-dependent degradation of the human estrogen receptor. Proc Natl Acad Sci USA 96(5):1858-1862 (Pubitemid 29117832)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.5
, pp. 1858-1862
-
-
Nawaz, Z.1
Lonard, D.M.2
Dennis, A.P.3
Smith, C.L.4
O'Malley, B.W.5
-
36
-
-
1542297619
-
Urban renewal in the nucleus: Is protein turnover by proteasomes absolutely required for nuclear receptor-regulated transcription?
-
DOI 10.1210/me.2003-0388
-
Nawaz Z, O'Malley BW (2004) Urban renewal in the nucleus: is protein turnover by proteasomes absolutely required for nuclear receptor-regulated transcription? Mol Endocrinol 18(3):493-499. doi:10.1210/me.2003-0388 (Pubitemid 38328197)
-
(2004)
Molecular Endocrinology
, vol.18
, Issue.3
, pp. 493-499
-
-
Nawaz, Z.1
O'Malley, B.W.2
-
37
-
-
0037331103
-
RING finger ubiquitin protein ligases: Implications for tumorigenesis, metastasis and for molecular targets in cancer
-
DOI 10.1016/S1044-579X(02)00095-0, PII S1044579X02000950
-
Fang S, Lorick KL, Jensen JP, Weissman AM (2003) RING finger ubiquitin protein ligases: implications for tumorigenesis, metastasis and for molecular targets in cancer. Semin Cancer Biol 13(1):5-14 (Pubitemid 36269176)
-
(2003)
Seminars in Cancer Biology
, vol.13
, Issue.1
, pp. 5-14
-
-
Fang, S.1
Lorick, K.L.2
Jensen, J.P.3
Weissman, A.M.4
-
38
-
-
1842486790
-
Ubiquitin and breast cancer
-
DOI 10.1038/sj.onc.1207371
-
Ohta T, Fukuda M (2004) Ubiquitin and breast cancer. Oncogene 23(11):2079-2088. doi:10.1038/sj.onc.1207371 (Pubitemid 38496737)
-
(2004)
Oncogene
, vol.23
, Issue.11 REV. ISS. 1
, pp. 2079-2088
-
-
Ohta, T.1
Fukuda, M.2
|