메뉴 건너뛰기




Volumn 456, Issue 7222, 2008, Pages 663-666

Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; SMALL INTERFERING RNA; TAMOXIFEN; TRANSCRIPTION FACTOR PAX2; TRASTUZUMAB;

EID: 57349113761     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature07483     Document Type: Article
Times cited : (272)

References (30)
  • 1
    • 0036488531 scopus 로고    scopus 로고
    • Endocrine-responsive breast cancer and strategies for combating resistance
    • Ali, S. & Coombes, R. C. Endocrine-responsive breast cancer and strategies for combating resistance. Nature Rev. 2, 101-112 (2002).
    • (2002) Nature Rev , vol.2 , pp. 101-112
    • Ali, S.1    Coombes, R.C.2
  • 2
    • 33750442923 scopus 로고    scopus 로고
    • Genome-wide analysis of estrogen receptor binding sites
    • Carroll, J. S. et al. Genome-wide analysis of estrogen receptor binding sites. Nature Genet. 38, 1289-1297 (2006).
    • (2006) Nature Genet , vol.38 , pp. 1289-1297
    • Carroll, J.S.1
  • 3
    • 22144486551 scopus 로고    scopus 로고
    • Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1
    • Carroll, J. S. et al. Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell 122, 33-43 (2005).
    • (2005) Cell , vol.122 , pp. 33-43
    • Carroll, J.S.1
  • 4
    • 40849085514 scopus 로고    scopus 로고
    • FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription
    • Lupien, M. et al. FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell 132, 958-970 (2008).
    • (2008) Cell , vol.132 , pp. 958-970
    • Lupien, M.1
  • 5
    • 0344255673 scopus 로고    scopus 로고
    • Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival
    • Muratovska, A. et al. Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival. Oncogene 22, 7989-7997 (2003).
    • (2003) Oncogene , vol.22 , pp. 7989-7997
    • Muratovska, A.1
  • 6
    • 30144433414 scopus 로고    scopus 로고
    • Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis
    • Wu, H. et al. Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis. Nature 438, 981-987 (2005).
    • (2005) Nature , vol.438 , pp. 981-987
    • Wu, H.1
  • 7
    • 0035101145 scopus 로고    scopus 로고
    • Cellular and molecular pharmacology of antiestrogen action and resistance
    • Clarke, R. et al. Cellular and molecular pharmacology of antiestrogen action and resistance. Pharmacol. Rev. 53, 25-71 (2001).
    • (2001) Pharmacol. Rev , vol.53 , pp. 25-71
    • Clarke, R.1
  • 8
    • 0037420192 scopus 로고    scopus 로고
    • Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer
    • Osborne, C. K. et al. Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer. J. Natl Cancer Inst. 95, 353-361 (2003).
    • (2003) J. Natl Cancer Inst , vol.95 , pp. 353-361
    • Osborne, C.K.1
  • 9
    • 0027074588 scopus 로고
    • Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu
    • Benz, C. C. et al. Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu. Breast Cancer Res. Treat. 24, 85-95 (1992).
    • (1992) Breast Cancer Res. Treat , vol.24 , pp. 85-95
    • Benz, C.C.1
  • 10
    • 0030865656 scopus 로고    scopus 로고
    • An intron 1 enhancer element mediates oestrogen-induced suppression of ERBB2 expression
    • Bates, N. P. & Hurst, H. C. An intron 1 enhancer element mediates oestrogen-induced suppression of ERBB2 expression. Oncogene 15, 473-481 (1997).
    • (1997) Oncogene , vol.15 , pp. 473-481
    • Bates, N.P.1    Hurst, H.C.2
  • 11
    • 1242338758 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators: Discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells
    • Frasor, J. et al. Selective estrogen receptor modulators: discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells. Cancer Res. 64, 1522-1533 (2004).
    • (2004) Cancer Res , vol.64 , pp. 1522-1533
    • Frasor, J.1
  • 12
    • 0348013132 scopus 로고    scopus 로고
    • Classifying the estrogen receptor status of breast cancers by expression profiles reveals a poor prognosis subpopulation exhibiting high expression of the ERBB2 receptor
    • Kun, Y. et al. Classifying the estrogen receptor status of breast cancers by expression profiles reveals a poor prognosis subpopulation exhibiting high expression of the ERBB2 receptor. Hum. Mol. Genet. 12, 3245-3258 (2003).
    • (2003) Hum. Mol. Genet , vol.12 , pp. 3245-3258
    • Kun, Y.1
  • 13
    • 26844503270 scopus 로고    scopus 로고
    • Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
    • Piccart-Gebhart, M. J. et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N. Engl. J. Med. 353, 1659-1672 (2005).
    • (2005) N. Engl. J. Med , vol.353 , pp. 1659-1672
    • Piccart-Gebhart, M.J.1
  • 14
    • 0030797902 scopus 로고    scopus 로고
    • AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer
    • Anzick, S. L. et al. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science 277, 965-968 (1997).
    • (1997) Science , vol.277 , pp. 965-968
    • Anzick, S.L.1
  • 15
    • 4544314561 scopus 로고    scopus 로고
    • High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene
    • Torres-Arzayus, M. I. et al. High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene. Cancer Cell 6, 263-274 (2004).
    • (2004) Cancer Cell , vol.6 , pp. 263-274
    • Torres-Arzayus, M.I.1
  • 16
    • 45549110356 scopus 로고    scopus 로고
    • The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice
    • Fereshteh, M. P. et al. The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice. Cancer Res. 68, 3697-3706 (2008).
    • (2008) Cancer Res , vol.68 , pp. 3697-3706
    • Fereshteh, M.P.1
  • 17
    • 2942628182 scopus 로고    scopus 로고
    • ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance
    • Louie, M. C. et al. ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance. Mol. Cell. Biol. 24, 5157-5171 (2004).
    • (2004) Mol. Cell. Biol , vol.24 , pp. 5157-5171
    • Louie, M.C.1
  • 18
    • 0037373326 scopus 로고    scopus 로고
    • Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells
    • Knowlden, J. M. et al. Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells. Endocrinology 144, 1032-1044 (2003).
    • (2003) Endocrinology , vol.144 , pp. 1032-1044
    • Knowlden, J.M.1
  • 19
    • 0029113686 scopus 로고
    • Changes in estrogen receptor, progesterone receptor, and pS2 expression in tamoxifen-resistant human breast cancer
    • Johnston, S. R. et al. Changes in estrogen receptor, progesterone receptor, and pS2 expression in tamoxifen-resistant human breast cancer. Cancer Res. 55, 3331-3338 (1995).
    • (1995) Cancer Res , vol.55 , pp. 3331-3338
    • Johnston, S.R.1
  • 20
    • 34548248572 scopus 로고    scopus 로고
    • Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state
    • Green, K. A. & Carroll, J. S. Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state. Nature Rev. 7, 713-722 (2007).
    • (2007) Nature Rev , vol.7 , pp. 713-722
    • Green, K.A.1    Carroll, J.S.2
  • 21
    • 25844495364 scopus 로고    scopus 로고
    • The NFκB pathway and endocrine-resistant breast cancer
    • Zhou, Y. et al. The NFκB pathway and endocrine-resistant breast cancer. Endocr. Relat. Cancer 12 (Suppl 1), S37-S46 (2005).
    • (2005) Endocr. Relat. Cancer , vol.12 , Issue.SUPPL. 1
    • Zhou, Y.1
  • 22
    • 18344392446 scopus 로고    scopus 로고
    • Identification of amplified and expressed genes in breast cancer by comparative hybridization onto microarrays of randomly selected cDNA clones
    • Clark, J. et al. Identification of amplified and expressed genes in breast cancer by comparative hybridization onto microarrays of randomly selected cDNA clones. Genes Chromosom. Cancer 34, 104-114 (2002).
    • (2002) Genes Chromosom. Cancer , vol.34 , pp. 104-114
    • Clark, J.1
  • 23
    • 0034794636 scopus 로고    scopus 로고
    • Overexpression of HER-2 as a resistance mechanism to hormonal therapy for breast cancer
    • Dowsett, M. Overexpression of HER-2 as a resistance mechanism to hormonal therapy for breast cancer. Endocr. Relat. Cancer 8, 191-195 (2001).
    • (2001) Endocr. Relat. Cancer , vol.8 , pp. 191-195
    • Dowsett, M.1
  • 24
    • 0035576786 scopus 로고    scopus 로고
    • HER-2 amplification impedes the antiproliferative effects of hormone therapy in estrogen receptor-positive primary breast cancer
    • Dowsett, M. et al. HER-2 amplification impedes the antiproliferative effects of hormone therapy in estrogen receptor-positive primary breast cancer. Cancer Res. 61, 8452-8458 (2001).
    • (2001) Cancer Res , vol.61 , pp. 8452-8458
    • Dowsett, M.1
  • 25
    • 35348904493 scopus 로고    scopus 로고
    • Phosphorylation of estrogen receptor-α at Ser167 is indicative of longer disease-free and overall survival in breast cancer patients
    • Jiang, J. et al. Phosphorylation of estrogen receptor-α at Ser167 is indicative of longer disease-free and overall survival in breast cancer patients. Clin. Cancer Res. 13, 5769-5776 (2007).
    • (2007) Clin. Cancer Res , vol.13 , pp. 5769-5776
    • Jiang, J.1
  • 26
    • 27944492407 scopus 로고    scopus 로고
    • Tamoxifen for the prevention of breast cancer: Current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study
    • Fisher, B. et al. Tamoxifen for the prevention of breast cancer: current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study. J. Natl Cancer Inst. 97, 1652-1662 (2005).
    • (2005) J. Natl Cancer Inst , vol.97 , pp. 1652-1662
    • Fisher, B.1
  • 27
    • 33845209913 scopus 로고    scopus 로고
    • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
    • Neve, R. M. et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10, 515-527 (2006).
    • (2006) Cancer Cell , vol.10 , pp. 515-527
    • Neve, R.M.1
  • 28
    • 33747587864 scopus 로고    scopus 로고
    • Model-based analysis of tiling-arrays for ChIP-chip
    • Johnson, W. E. et al. Model-based analysis of tiling-arrays for ChIP-chip. Proc. Natl Acad. Sci. USA 103, 12457-12462 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 12457-12462
    • Johnson, W.E.1
  • 29
    • 0034623995 scopus 로고    scopus 로고
    • A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence
    • Carroll, J. S. et al. A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence. J. Biol. Chem. 275, 38221-38229 (2000).
    • (2000) J. Biol. Chem , vol.275 , pp. 38221-38229
    • Carroll, J.S.1
  • 30
    • 34548565667 scopus 로고    scopus 로고
    • Quantitative analysis of chromosome conformation capture assays (3C-qPCR)
    • Hagege, H. et al. Quantitative analysis of chromosome conformation capture assays (3C-qPCR). Nature Protocols 2, 1722-1733 (2007).
    • (2007) Nature Protocols , vol.2 , pp. 1722-1733
    • Hagege, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.