-
1
-
-
0025338591
-
Development of antiestrogens and thier use in breast cancer: Eighth Cain Memorial Award Lecture
-
Lerner LJ, Jordan VC 1990 Development of antiestrogens and thier use in breast cancer: Eighth Cain Memorial Award Lecture. Cancer Res 50:4177-4189
-
(1990)
Cancer Res
, vol.50
, pp. 4177-4189
-
-
Lerner, L.J.1
Jordan, V.C.2
-
2
-
-
0024546736
-
Adjuvant tamoxifen in early breast cancer: Occurrence of new primary cancers
-
Fornander T, Rutquist LE, Cedennark B, Glas U, Mattson A, Siljverward JD, Skoog L, Somell A, Theve T, Wilking N, Askergren J, Hjolmar ML 1989 Adjuvant tamoxifen in early breast cancer: occurrence of new primary cancers. Lancet 1:117-120
-
(1989)
Lancet
, vol.1
, pp. 117-120
-
-
Fornander, T.1
Rutquist, L.E.2
Cedennark, B.3
Glas, U.4
Mattson, A.5
Siljverward, J.D.6
Skoog, L.7
Somell, A.8
Theve, T.9
Wilking, N.10
Askergren, J.11
Hjolmar, M.L.12
-
3
-
-
0028886694
-
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
-
Kato S, Endoh H, Masuhiro Y, Kitamoto T, Uchiyama S, Sasaki H, Masushige S, Gotoh Y, Nishida E, Kawashima H, Metzger D, Chambon P 1995 Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270:1491-1494
-
(1995)
Science
, vol.270
, pp. 1491-1494
-
-
Kato, S.1
Endoh, H.2
Masuhiro, Y.3
Kitamoto, T.4
Uchiyama, S.5
Sasaki, H.6
Masushige, S.7
Gotoh, Y.8
Nishida, E.9
Kawashima, H.10
Metzger, D.11
Chambon, P.12
-
4
-
-
0029877913
-
Activation of the unli-ganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation
-
Bunone G, Briand P-A, Miksicek RJ, Picard D 1996 Activation of the unli-ganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO J 15:2174-2183
-
(1996)
EMBO J
, vol.15
, pp. 2174-2183
-
-
Bunone, G.1
Briand, P.-A.2
Miksicek, R.J.3
Picard, D.4
-
5
-
-
0031043390
-
Cloning, chromosomal localization and functional analysis of the murine estrogen receptor 0
-
Tremblay GB, Tremblay A, Copeland NG, Gilbert DJ, Jenkins NA, Labrie F, Giguere V 1997 Cloning, chromosomal localization and functional analysis of the murine estrogen receptor 0. Mol Endocrinol 11:353-365
-
(1997)
Mol Endocrinol
, vol.11
, pp. 353-365
-
-
Tremblay, G.B.1
Tremblay, A.2
Copeland, N.G.3
Gilbert, D.J.4
Jenkins, N.A.5
Labrie, F.6
Giguere, V.7
-
6
-
-
0026701699
-
ICI 182, 780, a new antioestrogen with clinical potential
-
Wakeling AE, Bowler J 1992 ICI 182, 780, a new antioestrogen with clinical potential. J Steroid Biochem Mol Biol 43:173-177
-
(1992)
J Steroid Biochem Mol Biol
, vol.43
, pp. 173-177
-
-
Wakeling, A.E.1
Bowler, J.2
-
7
-
-
0028084758
-
Investigation of a new pure antiestrogen (ICI 182780) in women with primary breast cancer
-
DeFriend DJ, Howell A, Nicholson RI, Anderson E, Dowsett M, Mansel RE, Blarney RW, Bundred NJ, Robertson JF, Saunders C, Baum M, Walton P, Sutcliffe F, Wakeling AE 1994 Investigation of a new pure antiestrogen (ICI 182780) in women with primary breast cancer. Cancer Res 54:408-414
-
(1994)
Cancer Res
, vol.54
, pp. 408-414
-
-
Defriend, D.J.1
Howell, A.2
Nicholson, R.I.3
Anderson, E.4
Dowsett, M.5
Mansel, R.E.6
Blarney, R.W.7
Bundred, N.J.8
Robertson, J.F.9
Saunders, C.10
Baum, M.11
Walton, P.12
Sutcliffe, F.13
Wakeling, A.E.14
-
8
-
-
0028861402
-
Response to a specific antiestrogen (ICI 182780) in tamoxifen-resistant breast cancer
-
Howell A, DeFriend DJ, Robertson J, Blarney R, Walton P 1995 Response to a specific antiestrogen (ICI 182780) in tamoxifen-resistant breast cancer. Lancet 345:29-30
-
(1995)
Lancet
, vol.345
, pp. 29-30
-
-
Howell, A.1
Defriend, D.J.2
Robertson, J.3
Blarney, R.4
Walton, P.5
-
9
-
-
0022473069
-
Sequence and expression of human estrogen receptor complementary DNA
-
Greene GL, Gilna P, Waterfield M, Baker A, Hort Y, Shine J 1986 Sequence and expression of human estrogen receptor complementary DNA. Science 231:1150-1154
-
(1986)
Science
, vol.231
, pp. 1150-1154
-
-
Greene, G.L.1
Gilna, P.2
Waterfield, M.3
Baker, A.4
Hort, Y.5
Shine, J.6
-
10
-
-
0022653964
-
Human oestrogen receptor cDNA: Sequence, expression and homology to v-erbA
-
Green S, Walter P, Kumar V, Krust A, Bornet JM, Argos P, Chambon P 1986 Human oestrogen receptor cDNA: sequence, expression and homology to v-erbA. Nature 320:134-139
-
(1986)
Nature
, vol.320
, pp. 134-139
-
-
Green, S.1
Walter, P.2
Kumar, V.3
Krust, A.4
Bornet, J.M.5
Argos, P.6
Chambon, P.7
-
11
-
-
0023628759
-
Parker M1987 Structural organization and expression of the mouse estrogen receptor
-
White R, Lees JA, Needham M, Ham J, Parker M1987 Structural organization and expression of the mouse estrogen receptor. Mol Endocrinol 1:735-744
-
Mol Endocrinol
, vol.1
, pp. 735-744
-
-
White, R.1
Lees, J.A.2
Needham, M.3
Ham, J.4
-
12
-
-
0030593681
-
ERβ: Identification and characterization of a novel human estrogen receptor
-
Mosselman S, Polman J, Dijkema R 1996 ERβ: identification and characterization of a novel human estrogen receptor. FEBS Lett 392:49-53
-
(1996)
FEBS Lett
, vol.392
, pp. 49-53
-
-
Mosselman, S.1
Polman, J.2
Dijkema, R.3
-
13
-
-
0030579801
-
Cloning of a novel estrogen receptor expressed in rat prostate and ovary
-
Kuiper GGJM, Enmark E, Pelto-Huikko M, Nilsson S, Gustafsson J-A 1996 Cloning of a novel estrogen receptor expressed in rat prostate and ovary. Proc Natl Acad Sci USA 93:5925-5930
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5925-5930
-
-
Kuiper, G.1
Enmark, E.2
Pelto-Huikko, M.3
Nilsson, S.4
Gustafsson, J.-A.5
-
14
-
-
0022720813
-
Chambon P1986 The chicken oestrogen receptor sequence: Homology with v-erbA and the human oestrogen and glucocorticoid receptors
-
Krust A, Green S, Argos P, Kumar V, Walter P, Bomert J-M, Chambon P1986 The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors. EMBO J 5:891-897
-
EMBO J
, vol.5
, pp. 891-897
-
-
Krust, A.1
Green, S.2
Argos, P.3
Kumar, V.4
Walter, P.5
Bomert, J.-M.6
-
15
-
-
0023663885
-
Functional domains of the human estrogen receptor
-
Kumar V, Green S, Stack G, Berry M, Jin JR, Chambon P 1987 Functional domains of the human estrogen receptor. Cell 51:941-951
-
(1987)
Cell
, vol.51
, pp. 941-951
-
-
Kumar, V.1
Green, S.2
Stack, G.3
Berry, M.4
Jin, J.R.5
Chambon, P.6
-
16
-
-
0025062215
-
Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen
-
Berry M, Metzger D, Chambon P 1990 Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen. EMBO J 9:2811-2818
-
(1990)
EMBO J
, vol.9
, pp. 2811-2818
-
-
Berry, M.1
Metzger, D.2
Chambon, P.3
-
17
-
-
0028901040
-
Characterization of the amino-terminal transcriptional activation function of the human estrogen receptor in animal and yeast cells
-
Metzger D, Ali S, Bornert JM, Chambon 'P 1995 Characterization of the amino-terminal transcriptional activation function of the human estrogen receptor in animal and yeast cells. J Biol Chem 270:9535-9542
-
(1995)
J Biol Chem
, vol.270
, pp. 9535-9542
-
-
Metzger, D.1
Ali, S.2
Bornert, J.M.3
-
18
-
-
0029121358
-
Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor
-
Cavailles V, Dauvois S, L'Horset F, Lopez G, Hoare S, Kushner PJ, Parker MG 1995 Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor. EMBO J 14:3741-3751
-
(1995)
EMBO J
, vol.14
, pp. 3741-3751
-
-
Cavailles, V.1
Dauvois, S.2
L'horset, F.3
Lopez, G.4
Hoare, S.5
Kushner, P.J.6
Parker, M.G.7
-
19
-
-
0028846193
-
Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
-
Onate SA, Tsai SY, Tsai M-J, O'Malley BW 1995 Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270:1354-1357
-
(1995)
Science
, vol.270
, pp. 1354-1357
-
-
Onate, S.A.1
Tsai, S.Y.2
Tsai, M.-J.3
O'malley, B.W.4
-
20
-
-
0028233383
-
Brown M1994 Estrogen receptor-associated proteins: Possible mediators of hormone-in-duced transcription
-
Halachmi S, Marden E, Martin G, MacKay H, Abbondanza C, Brown M1994 Estrogen receptor-associated proteins: possible mediators of hormone-in-duced transcription. Science 264:1455-1458
-
Science
, vol.264
, pp. 1455-1458
-
-
Halachmi, S.1
Marden, E.2
Martin, G.3
Mackay, H.4
Abbondanza, C.5
-
21
-
-
0029740105
-
Nuclear receptor coactivators and corepressors
-
Horwitz KB, Jackson TA, Rain DL, Richer JK, Takimoto GS, Tung L 1996 Nuclear receptor coactivators and corepressors. Mol Endocrinol 10:1167-1177
-
(1996)
Mol Endocrinol
, vol.10
, pp. 1167-1177
-
-
Horwitz, K.B.1
Jackson, T.A.2
Rain, D.L.3
Richer, J.K.4
Takimoto, G.S.5
Tung, L.6
-
22
-
-
0029954339
-
TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors
-
Voegel JJ, Heine MJS, Zechel C, Chambon P, Gronemeyer H 1996 TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors. EMBO J 15:3667-3675
-
(1996)
EMBO J
, vol.15
, pp. 3667-3675
-
-
Voegel, J.J.1
Heine, M.2
Zechel, C.3
Chambon, P.4
Gronemeyer, H.5
-
23
-
-
0030879732
-
Characterization of the effects of the novel non-steroidal antiestrogen EM-800 on basal and estrogen-induced proliferation of T47D, ZR-75-1 and MCF-7 human breast cancer cells in vitro
-
Simard J, Labrie C, Belanger A, Gauthier S, Singh SM, Merand Y, Labrie F 1997 Characterization of the effects of the novel non-steroidal antiestrogen EM-800 on basal and estrogen-induced proliferation of T47D, ZR-75-1 and MCF-7 human breast cancer cells in vitro. Int J Cancer 73:104-112
-
(1997)
Int J Cancer
, vol.73
, pp. 104-112
-
-
Simard, J.1
Labrie, C.2
Belanger, A.3
Gauthier, S.4
Singh, S.M.5
Merand, Y.6
Labrie, F.7
-
24
-
-
0025354926
-
Identification of a novel isoform of the retinoic acid receptor y expressed in the mouse embryo. Mol
-
Giguere V, Shago M, Zirngibl R, Tate P, Rossant J, Varmuza S 1990 Identification of a novel isoform of the retinoic acid receptor y expressed in the mouse embryo. Mol. Cell Biol 10:2335-2340
-
(1990)
Cell Biol
, vol.10
, pp. 2335-2340
-
-
Giguere, V.1
Shago, M.2
Zirngibl, R.3
Tate, P.4
Rossant, J.5
Varmuza, S.6
-
25
-
-
0024493779
-
O'Malley BW1989 Specific binding of estrogen receptor to the estrogen reponse element
-
Klein-Hitpass L, Tsai SY, Greene GL, Clark JH, Tsai M-J, O'Malley BW1989 Specific binding of estrogen receptor to the estrogen reponse element. Mol Cell Biol 9:43-49
-
Mol Cell Biol
, vol.9
, pp. 43-49
-
-
Klein-Hitpass, L.1
Tsai, S.Y.2
Greene, G.L.3
Clark, J.H.4
Tsai, M.-J.5
-
26
-
-
0024317270
-
Chambon P1989 The human estrogen receptor has two independent nonacidic transcriptional activation functions
-
Tora L, White J, Brou C, Tasset D, Webster N, Scheer E, Chambon P1989 The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell 59:477-487
-
Cell
, vol.59
, pp. 477-487
-
-
Tora, L.1
White, J.2
Brou, C.3
Tasset, D.4
Webster, N.5
Scheer, E.6
-
27
-
-
0029044210
-
Effects of antagonists on DNA binding properties of the human estrogen receptor in vitro and in vivo
-
Metzger D, Berry M, Ali S, Chambon P 1995 Effects of antagonists on DNA binding properties of the human estrogen receptor in vitro and in vivo. Mol Endocrinol 9:579-591
-
(1995)
Mol Endocrinol
, vol.9
, pp. 579-591
-
-
Metzger, D.1
Berry, M.2
Ali, S.3
Chambon, P.4
-
28
-
-
0027405070
-
Chambon P1993 Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region
-
Ali S, Metzger D, Bornert J-M, Chambon P1993 Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region. EMBO J 12:1153-1160
-
EMBO J
, vol.12
, pp. 1153-1160
-
-
Ali, S.1
Metzger, D.2
Bornert, J.-M.3
-
29
-
-
0001235572
-
Estrogen-responsive element of the human pS2 gene is an imperfectly palindromic sequence
-
Berry M, Nunez A-M, Chambon P 1989 Estrogen-responsive element of the human pS2 gene is an imperfectly palindromic sequence. Proc Natl Acad Sci USA 86:1218-1222
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 1218-1222
-
-
Berry, M.1
Nunez, A.-M.2
Chambon, P.3
-
30
-
-
0029790142
-
Katzenellenbogen BS1996 Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator
-
Mclnerney EM, Tsai M-J, O'Malley BW, Katzenellenbogen BS1996 Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator. Proc Natl Acad Sci USA 93:10069-10073
-
Proc Natl Acad Sci USA
, vol.93
, pp. 10069-10073
-
-
McLnerney, E.M.1
Tsai, M.-J.2
O'malley, B.W.3
-
31
-
-
0021618186
-
The pharmacology and clinical uses of tamoxifen
-
Furr BJ, Jordan VC 1984 The pharmacology and clinical uses of tamoxifen. Pharmacol Ther 25:127-205
-
(1984)
Pharmacol Ther
, vol.25
, pp. 127-205
-
-
Furr, B.J.1
Jordan, V.C.2
-
32
-
-
0029077113
-
Responses to pure antiestrogens (ICI 164384, ICI 182780) in estrogen-sensitive and -resistant experimental and clinical breast cancer
-
Nicholson RI, Gee JM, Manning DL, Wakeling AE, Montano MM, Katzenellenbogen BS 1995 Responses to pure antiestrogens (ICI 164384, ICI 182780) in estrogen-sensitive and -resistant experimental and clinical breast cancer. Ann NY Acad Sci 761:148-163
-
(1995)
Ann NY Acad Sci
, vol.761
, pp. 148-163
-
-
Nicholson, R.I.1
Gee, J.M.2
Manning, D.L.3
Wakeling, A.E.4
Montano, M.M.5
Katzenellenbogen, B.S.6
-
33
-
-
0030793285
-
Labrie F 1997 (S)-(+)[4-[7-2, 2-Dimethyl-l-oxo-propoxy)-4-methy 1 - 2 - [4 - [2 - (1 - piperidiny l)ethoxy]pheny 1] - 2H -1-1 benzopy-ran-3-yl]phenyl]-2, 2-dimethylpropanoate (EM-800): A highly potent nonsteroidal antiestrogen
-
Gauthier S, Caron B, Cloutier J, Dory YL, Favre A, Larouche D, Mailhot J, Ouellet C, Schwerdtfeger A, Leblanc G, Martel C, Simard J, Merand Y, Belanger A, Labrie C, Labrie F 1997 (s)-(+)[4-[7-2, 2-Dimethyl-l-oxo-propoxy)-4-methy 1 - 2 - [4 - [2 - (1 - piperidiny l)ethoxypheny 1] - 2H -1-1 benzopy-ran-3-yl]phenyl]-2, 2-dimethylpropanoate (EM-800): a highly potent nonsteroidal antiestrogen. J Med Chem 40:2117-2122
-
J Med Chem
, vol.40
, pp. 2117-2122
-
-
Gauthier, S.1
Caron, B.2
Cloutier, J.3
Dory, Y.L.4
Favre, A.5
Larouche, D.6
Mailhot, J.7
Ouellet, C.8
Schwerdtfeger, A.9
Leblanc, G.10
Martel, C.11
Simard, J.12
Merand, Y.13
Belanger, A.14
Labrie, C.15
-
34
-
-
0027344351
-
The future of new pure antiestrogens in clinical breast cancer
-
Wakeling AE 1993 The future of new pure antiestrogens in clinical breast cancer. Breast Cancer Res Treat 25:1-9
-
(1993)
Breast Cancer Res Treat
, vol.25
, pp. 1-9
-
-
Wakeling, A.E.1
-
35
-
-
0018913822
-
Estrogen receptors in mammary' gland primordia of fetal mouse
-
Narbaitz R, Stumpf WE, Sar M 1980 Estrogen receptors in mammary' gland primordia of fetal mouse. Anat Embryol 158:161-166
-
(1980)
Anat Embryol
, vol.158
, pp. 161-166
-
-
Narbaitz, R.1
Stumpf, W.E.2
Sar, M.3
-
36
-
-
0026771568
-
The ontogeny and cellular distribution of estrogen receptors in normal mouse mammarv gland
-
Haslam SZ, Nummy KA 1992 The ontogeny and cellular distribution of estrogen receptors in normal mouse mammarv gland. J Steroid Biochem Mol Biol 42:589-595
-
(1992)
J Steroid Biochem Mol Biol
, vol.42
, pp. 589-595
-
-
Haslam, S.Z.1
Nummy, K.A.2
-
37
-
-
0026395885
-
A potent specific pure antiestrogen with clinical potential
-
Wakeling AE, Dukes M, Bowler J 1991 A potent specific pure antiestrogen with clinical potential. Cancer Res 51:3867-3873
-
(1991)
Cancer Res
, vol.51
, pp. 3867-3873
-
-
Wakeling, A.E.1
Dukes, M.2
Bowler, J.3
-
38
-
-
0017535591
-
Prestwich G1977 Binding of [3H]tamoxifen in rat uterine cytosols: A comparison of swinging bucket and vertical tube rotor sucrose density gradient analysis
-
Jordan VC, Prestwich G1977 Binding of [3H]tamoxifen in rat uterine cytosols: a comparison of swinging bucket and vertical tube rotor sucrose density gradient analysis. Mol Cell Endocrinol 8:179-188
-
Mol Cell Endocrinol
, vol.8
, pp. 179-188
-
-
Jordan, V.C.1
-
39
-
-
0018190261
-
Dose-related effects of non-steroidal antioestrogens nad oestrogens on the measurement of cytoplasmic oestrogen receptors in the rat and mouse uterus
-
Jordan VC, ftowsby L, Dix CJ, Prestwich G 1978 Dose-related effects of non-steroidal antioestrogens nad oestrogens on the measurement of cytoplasmic oestrogen receptors in the rat and mouse uterus. J Endocrinol 78:71-81
-
(1978)
J Endocrinol
, vol.78
, pp. 71-81
-
-
Jordan, V.C.1
Ftowsby, L.2
Dix, C.J.3
Prestwich, G.4
-
40
-
-
0021091890
-
Comparison of the biological effects of tamoxifen and a new antioestrogen (LY117018) on the immature rat uterus
-
Wakeling AE, O'Connor KM, Newboult E 1983 Comparison of the biological effects of tamoxifen and a new antioestrogen (LY117018) on the immature rat uterus. J Endocrinol 99:447-453
-
(1983)
J Endocrinol
, vol.99
, pp. 447-453
-
-
Wakeling, A.E.1
O'connor, K.M.2
Newboult, E.3
-
41
-
-
0029796605
-
Different regions in activation function-1 of the human estrogen receptor required for antiestrogen- and estradiol-dependent transcription activation
-
Mclnerney EM, Katzenellenbogen BS 1996 Different regions in activation function-1 of the human estrogen receptor required for antiestrogen- and estradiol-dependent transcription activation. J Biol Chem 271:24172-24178
-
(1996)
J Biol Chem
, vol.271
, pp. 24172-24178
-
-
McLnerney, E.M.1
Katzenellenbogen, B.S.2
|