-
1
-
-
0026597063
-
Alzheimer's disease: The amyloid cascade hypothesis
-
Hardy J. A., Higgins G. A., Alzheimer's disease: the amyloid cascade hypothesis Science 1992 256 5054 184 185
-
(1992)
Science
, vol.256
, Issue.5054
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
2
-
-
0025753852
-
The molecular pathology of Alzheimer's disease
-
Selkoe D. J., The molecular pathology of Alzheimer's disease Neuron 1991 6 4 487 498
-
(1991)
Neuron
, vol.6
, Issue.4
, pp. 487-498
-
-
Selkoe, D.J.1
-
3
-
-
67651180986
-
The amyloid hypothesis for Alzheimer's disease: A critical reappraisal
-
Hardy J., The amyloid hypothesis for Alzheimer's disease: a critical reappraisal Journal of Neurochemistry 2009 110 4 1129 1134
-
(2009)
Journal of Neurochemistry
, vol.110
, Issue.4
, pp. 1129-1134
-
-
Hardy, J.1
-
4
-
-
79955857718
-
Compounding artefacts with uncertainty, and an amyloid cascade hypothesis that is too big to fail
-
Castellani R. J., Smith M. A., Compounding artefacts with uncertainty, and an amyloid cascade hypothesis that is too big to fail Journal of Pathology 2011 224 2 147 152
-
(2011)
Journal of Pathology
, vol.224
, Issue.2
, pp. 147-152
-
-
Castellani, R.J.1
Smith, M.A.2
-
5
-
-
84655162701
-
Twenty years of Alzheimer's disease-causing mutations
-
Goate A., Hardy J., Twenty years of Alzheimer's disease-causing mutations Journal of Neurochemistry 2012 120 supplement 1 3 8
-
(2012)
Journal of Neurochemistry
, vol.120
, Issue.SUPPL. 1
, pp. 3-8
-
-
Goate, A.1
Hardy, J.2
-
6
-
-
80052266213
-
The amyloid cascade hypothesis for Alzheimer's disease: An appraisal for the development of therapeutics
-
Karran E., Mercken M., de Strooper B., The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics Nature Reviews Drug Discovery 2011 10 9 698 712
-
(2011)
Nature Reviews Drug Discovery
, vol.10
, Issue.9
, pp. 698-712
-
-
Karran, E.1
Mercken, M.2
De Strooper, B.3
-
7
-
-
79955769953
-
Soluble a oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors
-
Li S., Jin M., Koeglsperger T., Shepardson N. E., Shankar G. M., Selkoe D. J., Soluble a oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors Journal of Neuroscience 2011 31 18 6627 6638
-
(2011)
Journal of Neuroscience
, vol.31
, Issue.18
, pp. 6627-6638
-
-
Li, S.1
Jin, M.2
Koeglsperger, T.3
Shepardson, N.E.4
Shankar, G.M.5
Selkoe, D.J.6
-
8
-
-
84655162704
-
Soluble A oligomer production and toxicity
-
Larson and M. E., Lesné S. E., Soluble A oligomer production and toxicity Journal of Neurochemistry 2012 120 supplement 1 125 139
-
(2012)
Journal of Neurochemistry
, vol.120
, Issue.SUPPL. 1
, pp. 125-139
-
-
Larson, M.E.1
Lesné, S.E.2
-
9
-
-
28844456475
-
The development of anti-amyloid therapy for Alzheimer's disease: From secretase modulators to polymerisation inhibitors
-
DOI 10.2165/00023210-200519120-00002
-
Aisen P. S., The development of anti-amyloid therapy for Alzheimer's disease: from secretase modulators to polymerisation inhibitors CNS Drugs 2005 19 12 989 996 (Pubitemid 41775990)
-
(2005)
CNS Drugs
, vol.19
, Issue.12
, pp. 989-996
-
-
Aisen, P.S.1
-
11
-
-
42149125510
-
Amyloid-degrading enzymes as therapeutic targets in Alzheimer's disease
-
DOI 10.2174/156720508783954785
-
Nalivaeva N. N., Fisk L. R., Belyaev N. D., Turner A. J., Amyloid-degrading enzymes as therapeutic targets in Alzheimer's disease Current Alzheimer Research 2008 5 2 212 224 (Pubitemid 351536346)
-
(2008)
Current Alzheimer Research
, vol.5
, Issue.2
, pp. 212-224
-
-
Nalivaeva, N.N.1
Fisk, L.R.2
Belyaev, N.D.3
Turner, A.J.4
-
12
-
-
84655160768
-
Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease?
-
Nalivaeva N. N., Beckett C., Belyaev N. D., Turner A. J., Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease? Journal of Neurochemistry 2012 120 supplement 1 167 185
-
(2012)
Journal of Neurochemistry
, vol.120
, Issue.SUPPL. 1
, pp. 167-185
-
-
Nalivaeva, N.N.1
Beckett, C.2
Belyaev, N.D.3
Turner, A.J.4
-
13
-
-
33746809372
-
Physiological roles for amyloid peptides
-
Pearson H. A., Peers C., Physiological roles for amyloid peptides Journal of Physiology 2006 575 1 5 10
-
(2006)
Journal of Physiology
, vol.575
, Issue.1
, pp. 5-10
-
-
Pearson, H.A.1
Peers, C.2
-
14
-
-
33947575426
-
Does Aβ 42 have a function related to blood homeostasis?
-
DOI 10.1007/s11064-006-9221-9
-
Hardy J., Does A 42 have a function related to blood homeostasis? Neurochemical Research 2007 32 4-5 833 835 (Pubitemid 46481311)
-
(2007)
Neurochemical Research
, vol.32
, Issue.4-5
, pp. 833-835
-
-
Hardy, J.1
-
15
-
-
19944434132
-
Intracellular Aβ42 activates p53 promoter: A pathway to neurodegeneration in Alzheimer's disease
-
DOI 10.1096/fj.04-2637fje
-
Ohyagi Y., Asahara H., Chui D. H., Tsuruta Y., Sakae N., Miyoshi K., Yamada T., Kikuchi H., Taniwaki T., Murai H., Ikezoe K., Furuya H., Kawarabayashi T., Shoji M., Checler F., Iwaki T., Makifuchi T., Takeda K., Kira J. I., Tabira T., Intracellular A 42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease The FASEB Journal 2005 19 2 255 257 (Pubitemid 40189273)
-
(2005)
FASEB Journal
, vol.19
, Issue.2
, pp. 255-257
-
-
Ohyagi, Y.1
Asahara, H.2
Chui, D.-H.3
Tsuruta, Y.4
Sakae, N.5
Miyoshi, K.6
Yamada, T.7
Kikuchi, H.8
Taniwaki, T.9
Murai, H.10
Ikezoe, K.11
Furuya, H.12
Kawarabayashi, T.13
Shoji, M.14
Checler, F.15
Iwaki, T.16
Makifuchi, T.17
Takeda, K.18
Kira, J.-I.19
Tabira, T.20
more..
-
16
-
-
80053384785
-
Functional activity of the novel Alzheimer's amyloid -peptide interacting domain (A ID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes and in amyloidogenesis
-
Bailey J. A., Maloney B., Ge Y. W., Lahiri D. K., Functional activity of the novel Alzheimer's amyloid -peptide interacting domain (A ID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes and in amyloidogenesis Gene 2011 488 1-2 13 22
-
(2011)
Gene
, vol.488
, Issue.12
, pp. 13-22
-
-
Bailey, J.A.1
Maloney, B.2
Ge, Y.W.3
Lahiri, D.K.4
-
17
-
-
79954623282
-
Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy
-
Hawkes C. A., Hrtig W., Kacza J., Schliebs R., Weller R. O., Nicoll J. A., Carare R. O., Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy Acta Neuropathologica 2011 121 4 431 443
-
(2011)
Acta Neuropathologica
, vol.121
, Issue.4
, pp. 431-443
-
-
Hawkes, C.A.1
Hrtig, W.2
Kacza, J.3
Schliebs, R.4
Weller, R.O.5
Nicoll, J.A.6
Carare, R.O.7
-
18
-
-
0015973588
-
The purification and specificity of a neutral endopeptidase from rabbit kidney brush border
-
Kerr M. A., Kenny A. J., The purification and specificity of a neutral endopeptidase from rabbit kidney brush border Biochemical Journal 1974 137 3 477 488
-
(1974)
Biochemical Journal
, vol.137
, Issue.3
, pp. 477-488
-
-
Kerr, M.A.1
Kenny, A.J.2
-
19
-
-
0018073489
-
High affinity enkephalin degrading peptidase in brain is increased after morphine
-
Malfroy B., Swerts J. P., Guyon A., High affinity enkephalin degrading peptidase in brain is increased after morphine Nature 1978 276 5687 523 526 (Pubitemid 9055818)
-
(1978)
Nature
, vol.276
, Issue.5687
, pp. 523-526
-
-
Malfroy, B.1
Swerts, J.P.2
Guyon, A.3
-
20
-
-
0010374240
-
Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli
-
Matsas R., Fulcher I. S., Kenny A. J., Turner A. J., Substance P and [ Leu ]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli Proceedings of the National Academy of Sciences of the United States of America 1983 80 10 I 3111 3115 (Pubitemid 13104172)
-
(1983)
Proceedings of the National Academy of Sciences of the United States of America
, vol.80
, Issue.10
, pp. 3111-3115
-
-
Matsas, R.1
Fulcher, I.S.2
Kenny, A.J.3
Turner, A.J.4
-
21
-
-
0023796690
-
Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase
-
DOI 10.1084/jem.168.4.1247
-
Letarte M., Vera S., Tran R., Addis J. B. L., Onizuka R. J., Quackenbush E. J., Jongeneel C. V., McInnes R. R., Common acute lymphocytic leukemia antigen is identical to neutral endopeptidase Journal of Experimental Medicine 1988 168 4 1247 1253 (Pubitemid 18264863)
-
(1988)
Journal of Experimental Medicine
, vol.168
, Issue.4
, pp. 1247-1253
-
-
Letarte, M.1
Vera, S.2
Tran, R.3
Addis, J.B.L.4
Onizuka, R.J.5
Quackenbush, E.J.6
Jongeneel, C.V.7
McInnes, R.R.8
-
22
-
-
78650043649
-
Neprilysin is identical to skin fibroblast elastase: Its role in skin aging and UV responses
-
Morisaki N., Moriwaki S., Sugiyama-Nakagiri Y., Haketa K., Takema Y., Imokawa G., Neprilysin is identical to skin fibroblast elastase: its role in skin aging and UV responses The Journal of Biological Chemistry 2010 285 51 39819 39827
-
(2010)
The Journal of Biological Chemistry
, vol.285
, Issue.51
, pp. 39819-39827
-
-
Morisaki, N.1
Moriwaki, S.2
Sugiyama-Nakagiri, Y.3
Haketa, K.4
Takema, Y.5
Imokawa, G.6
-
23
-
-
0021211465
-
The metabolism of neuropeptides. The hydrolysis of peptides, including enkephalins, tachykinins and their analogues, by endopeptidase-24.11
-
Matsas R., Kenny A. J., Turner A. J., The metabolism of neuropeptides. The hydrolysis of peptides, including enkephalins, tachykinins and their analogues, by endopeptidase-24.11 Biochemical Journal 1984 223 2 433 440 (Pubitemid 14023015)
-
(1984)
Biochemical Journal
, vol.223
, Issue.2
, pp. 433-440
-
-
Matsas, R.1
Kenny, A.J.2
Turner, A.J.3
-
24
-
-
0021007899
-
Purification of endopeptidase-24.11 (enkephalinase) from pig brain by immunoadsorbent chromatography
-
Relton J. M., Gee N. S., Matsas R., Turner A. J., Kenny A. J., Purification of endopeptidase-24.11 (enkephalinase) from pig brain by immunoadsorbent chromatography Biochemical Journal 1983 215 3 519 523
-
(1983)
Biochemical Journal
, vol.215
, Issue.3
, pp. 519-523
-
-
Relton, J.M.1
Gee, N.S.2
Matsas, R.3
Turner, A.J.4
Kenny, A.J.5
-
25
-
-
0023868637
-
Molecular cloning and amino acid sequence of human enkephalinase (neutral endopeptidase)
-
DOI 10.1016/0014-5793(88)80828-7
-
Malfroy B., Kuang W. J., Seeburg P. H., Mason A. J., Schofield P. R., Molecular cloning and amino acid sequence of human enkephalinase (neutral endopeptidase) The FEBS Letters 1988 229 1 206 210 (Pubitemid 18058767)
-
(1988)
FEBS Letters
, vol.229
, Issue.1
, pp. 206-210
-
-
Malfroy, B.1
Kuang, W.-J.2
Seeburg, P.H.3
Mason, A.J.4
Schofield, P.R.5
-
26
-
-
0027143946
-
Study of a new endogenous inhibitor of enkephalin-degrading enzymes; pharmacological function and metabolism of Spinorphin
-
Nishimura K., Ueki M., Kaneto H., Hazato T., Study of a new endogenous inhibitor of enkephalin-degrading enzymes; pharmacological function and metabolism of spinorphin Japanese Journal of Anesthesiology 1993 42 11 1663 1670 (Pubitemid 24013834)
-
(1993)
Japanese Journal of Anesthesiology
, vol.42
, Issue.11
, pp. 1663-1670
-
-
Nishimura, K.1
Ueki, M.2
Kaneto, H.3
Hazato, T.4
-
27
-
-
0037815281
-
Sialorphin, a natural inhibitor of rat membrane-bound neutral endopeptidase that displays analgesic activity
-
DOI 10.1073/pnas.1431850100
-
Rougeot C., Messaoudi M., Hermitte V., Galle Rigault A., Blisnick T., Dugave C., Desor D., Rougeon F., Sialorphin, a natural inhibitor of rat membrane-bound neutral endopeptidase that displays analgesic activity Proceedings of the National Academy of Sciences of the United States of America 2003 100 14 8549 8554 (Pubitemid 36842581)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.14
, pp. 8549-8554
-
-
Rougeot, C.1
Messaoudi, M.2
Hermitte, V.3
Gaelle Rigault, A.4
Blisnick, T.5
Dugave, C.6
Desor, D.7
Rougeon, F.8
-
28
-
-
33845200443
-
Human Opiorphin, a natural antinociceptive modulator of opioid-dependent pathways
-
DOI 10.1073/pnas.0605865103
-
Wisner A., Dufour E., Messaoudi M., Nejdi A., Marcel A., Ungeheuer M. N., Rougeot C., Human Opiorphin, a natural antinociceptive modulator of opioid-dependent pathways Proceedings of the National Academy of Sciences of the United States of America 2006 103 47 17979 17984 (Pubitemid 44852271)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.47
, pp. 17979-17984
-
-
Wisner, A.1
Dufour, E.2
Messaoudi, M.3
Nejdi, A.4
Marcel, A.5
Ungeheuer, M.-N.6
Rougeot, C.7
-
29
-
-
0034681296
-
Structure of human neutral endopeptidase (neprilysin) complexed with phosphoramidon
-
Oefner C., D'Arcy A., Hennig M., Winkler F. K., Dale G. E., Structure of human neutral endopeptidase (neprilysin) complexed with phosphoramidon Journal of Molecular Biology 2000 296 2 341 349
-
(2000)
Journal of Molecular Biology
, vol.296
, Issue.2
, pp. 341-349
-
-
Oefner, C.1
D'Arcy, A.2
Hennig, M.3
Winkler, F.K.4
Dale, G.E.5
-
30
-
-
0035112440
-
The neprilysin (NEP) family of zinc metalloendopeptidases: Genomics and function
-
DOI 10.1002/1521-1878(200103)23:3<261::AID-BIES1036>3.0.CO;2-K
-
Turner A. J., Isaac R. E., Coates D., The neprilysin (NEP) family of zinc metalloendopeptidases: genomics and function Bioassay 2001 23 3 261 269 (Pubitemid 32192145)
-
(2001)
BioEssays
, vol.23
, Issue.3
, pp. 261-269
-
-
Turner, A.J.1
Elwyn Isaac, R.2
Coates, D.3
-
31
-
-
40349089029
-
Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships
-
ARTICLE 16
-
Bland N. D., Pinney J. W., Thomas J. E., Turner A. J., Isaac R. E., Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships BMC Evolutionary Biology 2008 8 1, article 16
-
(2008)
BMC Evolutionary Biology
, vol.8
, Issue.1
-
-
Bland, N.D.1
Pinney, J.W.2
Thomas, J.E.3
Turner, A.J.4
Isaac, R.E.5
-
32
-
-
0027278582
-
An immunoelectron microscopic study of pig substantia nigra shows co-localization of endopeptidase-24.11 with substance P
-
DOI 10.1016/0306-4522(93)90490-7
-
Barnes K., Turner A. J., Kenny A. J., An immunoelectron microscopic study of pig substantia nigra shows co-localization of endopeptidase-24.11 with substance P Neuroscience 1993 53 4 1073 1082 (Pubitemid 23126102)
-
(1993)
Neuroscience
, vol.53
, Issue.4
, pp. 1073-1082
-
-
Barnes, K.1
Turner, A.J.2
Kenny, A.J.3
-
33
-
-
34547240466
-
Effects of hypoxia and oxidative stress on expression of neprilysin in human neuroblastoma cells and rat cortical neurones and astrocytes
-
DOI 10.1007/s11064-007-9349-2
-
Fisk L., Nalivaeva N. N., Boyle J. P., Peers C. S., Turner A. J., Effects of hypoxia and oxidative stress on expression of neprilysin in human neuroblastoma cells and rat cortical neurones and astrocytes Neurochemical Research 2007 32 10 1741 1748 (Pubitemid 47428855)
-
(2007)
Neurochemical Research
, vol.32
, Issue.10
, pp. 1741-1748
-
-
Fisk, L.1
Nalivaeva, N.N.2
Boyle, J.P.3
Peers, C.S.4
Turner, A.J.5
-
34
-
-
51149120624
-
Microglial dysfunction and defective -amyloid clearance pathways in aging alzheimer's disease mice
-
Hickman S. E., Allison E. K., El Khoury J., Microglial dysfunction and defective -amyloid clearance pathways in aging alzheimer's disease mice Journal of Neuroscience 2008 28 33 8354 8360
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.33
, pp. 8354-8360
-
-
Hickman, S.E.1
Allison, E.K.2
El Khoury, J.3
-
35
-
-
0024520776
-
The common acute lymphoblastic leukemia antigen (CD10). Emancipation from a functional enigma
-
LeBien T. W., McCormack R. T., The common acute lymphoblastic leukemia antigen (CD10). Emancipation from a functional enigma Blood 1989 73 3 625 635 (Pubitemid 19069159)
-
(1989)
Blood
, vol.73
, Issue.3
, pp. 625-635
-
-
LeBien, T.W.1
McCormack, R.T.2
-
36
-
-
0031889217
-
Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression
-
DOI 10.1038/nm0198-050
-
Papandreou C. N., Usmani B., Geng Y. P., Bogenrieder T., Freeman R., Wilk S., Finstad C. L., Reuter V. E., Powell C. T., Scheinberg D., Magill C., Scher H. L., Albino A. P., Nanus D. M., Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression Nature Medicine 1998 4 1 50 57 (Pubitemid 28133079)
-
(1998)
Nature Medicine
, vol.4
, Issue.1
, pp. 50-57
-
-
Papandreou, C.N.1
Usmani, B.2
Geng, Y.3
Bogenrieder, T.4
Freeman, R.5
Wilk, S.6
Finstad, C.L.7
Reuter, V.E.8
Powell, C.T.9
Scheinberg, D.10
Magill, C.11
Scher, H.L.12
Albino, A.P.13
Nanus, D.M.14
-
37
-
-
0000672640
-
Endopeptidase 24.11/CD10 is down-regulated in renal cell cancer
-
Ghring B., Holzhausen H. J., Meye A., Heynemann H., Rebmann U., Langner J., Riemann D., Endopeptidase 24.11/CD10 is down-regulated in renal cell cancer International Journal of Molecular Medicine 1998 2 4 409 414
-
(1998)
International Journal of Molecular Medicine
, vol.2
, Issue.4
, pp. 409-414
-
-
Ghring, B.1
Holzhausen, H.J.2
Meye, A.3
Heynemann, H.4
Rebmann, U.5
Langner, J.6
Riemann, D.7
-
38
-
-
13344281017
-
Neutral endopeptidase: Variable expression in human lung, inactivation in lung cancer, and modulation of peptide-induced calcium flux
-
Cohen A. J., Bunn P. A., Franklin W., Magill-Solc C., Hartmann C., Helfrich B., Gilman L., Folkvord J., Helm K., Miller Y. E., Neutral endopeptidase: variable expression in human lung, inactivation in lung cancer, and modulation of peptide-induced calcium flux Cancer Research 1996 56 4 831 839 (Pubitemid 26055474)
-
(1996)
Cancer Research
, vol.56
, Issue.4
, pp. 831-839
-
-
Cohen, A.J.1
Bunn, P.A.2
Franklin, W.3
Magill-Solc, C.4
Hartmann, C.5
Helfrich, B.6
Gilman, L.7
Folkvord, J.8
Helm, K.9
Miller, Y.E.10
-
39
-
-
0004187426
-
Organization of the gene encoding common acute lymphoblastic leukemia antigen (neutral endopeptidase 24.11): Multiple miniexons and separate 5' untranslated regions
-
D'Adamio L., Shipp M. A., Masteller E. L., Reinherz E. L., Organization of the gene encoding common acute lymphoblastic leukemia antigen (neutral endopeptidase 24.11): multiple miniexons and separate 5′ untranslated regions Proceedings of the National Academy of Sciences of the United States of America 1989 86 18 7103 7107 (Pubitemid 19240873)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.18
, pp. 7103-7107
-
-
D'Adamio, L.1
Shipp, M.A.2
Masteller, E.L.3
Reinherz, E.L.4
-
40
-
-
0028906255
-
Tissue-specific expression of rat neutral endopeptidase (neprilysin) mRNAs
-
Li C., Booze R. M., Hersh L. B., Tissue-specific expression of rat neutral endopeptidase (neprilysin) mRNAs The Journal of Biological Chemistry 1995 270 11 5723 5728
-
(1995)
The Journal of Biological Chemistry
, vol.270
, Issue.11
, pp. 5723-5728
-
-
Li, C.1
Booze, R.M.2
Hersh, L.B.3
-
41
-
-
0029040138
-
Neutral endopeptidase modulation of septic shock
-
Lu B., Gerard N. P., Kolakowski L. F., Bozza M., Zurakowski D., Finco O., Carroll M. C., Gerard C., Neutral endopeptidase modulation of septic shock Journal of Experimental Medicine 1995 181 6 2271 2275
-
(1995)
Journal of Experimental Medicine
, vol.181
, Issue.6
, pp. 2271-2275
-
-
Lu, B.1
Gerard, N.P.2
Kolakowski, L.F.3
Bozza, M.4
Zurakowski, D.5
Finco, O.6
Carroll, M.C.7
Gerard, C.8
-
42
-
-
0034704450
-
Alterations within the endogenous opioid system in mice with targeted deletion of the neutral endopeptidase (enkephalinase) gene
-
Fischer H. S., Zernig G., Schuligoi R., Miczek K. A., Hauser K. F., Gerard C., Saria A., Alterations within the endogenous opioid system in mice with targeted deletion of the neutral endopeptidase (enkephalinase) gene Regulatory Peptides 2000 96 1-2 53 58
-
(2000)
Regulatory Peptides
, vol.96
, Issue.12
, pp. 53-58
-
-
Fischer, H.S.1
Zernig, G.2
Schuligoi, R.3
Miczek, K.A.4
Hauser, K.F.5
Gerard, C.6
Saria, A.7
-
43
-
-
0034595580
-
Neutral endopeptidase and alcohol consumption, experiments in neutral endopeptidase-deficient mice
-
DOI 10.1016/S0014-2999(00)00222-3, PII S0014299900002223
-
Siems W. E., Maul B., Krause W., Gerard C., Hauser K. F., Hersh L. B., Fischer H. S., Zernig G., Saria A., Neutral endopeptidase and alcohol consumption, experiments in neutral endopeptidase-deficient mice European Journal of Pharmacology 2000 397 2-3 327 334 (Pubitemid 30323785)
-
(2000)
European Journal of Pharmacology
, vol.397
, Issue.2-3
, pp. 327-334
-
-
Siems, W.-E.1
Maul, B.2
Krause, W.3
Gerard, C.4
Hauser, K.F.5
Hersh, L.B.6
Fischer, H.S.7
Zernig, G.8
Saria, A.9
-
44
-
-
0024237316
-
Endopeptidase-24.11 is striosomally ordered in pig brain and, in contrast to aminopeptidase N and peptidyl dipeptidase A ('angiotensin converting enzyme'), is a marker for a set of striatal efferent fibres
-
DOI 10.1016/0306-4522(88)90184-4
-
Barnes K., Matsas R., Hooper N. M., Turner A. J., Kenny A. J., Endopeptidase-24.11 is striosomally ordered in pig brain and, in contrast to aminopeptidase N and peptidyl dipeptidase A (angiotensin converting enzyme), is a marker for a set of striatal efferent fibres Neuroscience 1988 27 3 799 817 (Pubitemid 19025388)
-
(1988)
Neuroscience
, vol.27
, Issue.3
, pp. 799-817
-
-
Barnes, K.1
Matsas, R.2
Hooper, N.M.3
Turner, A.J.4
Kenny, A.J.5
-
45
-
-
0028952265
-
Endopeptidase-24.11 is the integral membrane peptidase initiating degradation of somatostatin in the hippocampus
-
Barnes K., Doherty S., Turner A. J., Endopeptidase-24.11 is the integral membrane peptidase initiating degradation of somatostatin in the hippocampus Journal of Neurochemistry 1995 64 4 1826 1832
-
(1995)
Journal of Neurochemistry
, vol.64
, Issue.4
, pp. 1826-1832
-
-
Barnes, K.1
Doherty, S.2
Turner, A.J.3
-
46
-
-
0026741209
-
Membrane localization of endopeptidase-24.11 and peptidyl dipeptidase A (angiotensin converting enzyme) in the pig brain: A study using subcellular fractionation and electron microscopic immunocytochemistry
-
Barnes K., Turner A. J., Kenny A. J., Membrane localization of endopeptidase-24.11 and peptidyl dipeptidase A (angiotensin converting enzyme) in the pig brain: a study using subcellular fractionation and electron microscopic immunocytochemistry Journal of Neurochemistry 1992 58 6 2088 2096
-
(1992)
Journal of Neurochemistry
, vol.58
, Issue.6
, pp. 2088-2096
-
-
Barnes, K.1
Turner, A.J.2
Kenny, A.J.3
-
47
-
-
0025864420
-
Endopeptidase-24.11, a cell-surface peptidase of central nervous system neurons, is expressed by Schwann cells in the pig peripheral nervous system
-
Kioussi C., Matsas R., Endopeptidase-24.11, a cell-surface peptidase of central nervous system neurons, is expressed by Schwann cells in the pig peripheral nervous system Journal of Neurochemistry 1991 57 2 431 440
-
(1991)
Journal of Neurochemistry
, vol.57
, Issue.2
, pp. 431-440
-
-
Kioussi, C.1
Matsas, R.2
-
48
-
-
0029050033
-
Expression of endopeptidase-24.11 (common acute lymphoblastic leukaemia antigen CD10) in the sciatic nerve of the adult rat after lesion and during regeneration
-
Kioussi C., Mamalaki A., Jessen K., Mirsky R., Hersh L. B., Matsas R., Expression of endopeptidase-24.11 (common acute lymphoblastic leukaemia antigen CD10) in the sciatic nerve of the adult rat after lesion and during regeneration European Journal of Neuroscience 1995 7 5 951 961
-
(1995)
European Journal of Neuroscience
, vol.7
, Issue.5
, pp. 951-961
-
-
Kioussi, C.1
Mamalaki, A.2
Jessen, K.3
Mirsky, R.4
Hersh, L.B.5
Matsas, R.6
-
49
-
-
79955717337
-
Hypoxia-induced down-regulation of neprilysin by histone modification in mouse primary cortical and Hippocampal neurons
-
Wang Z., Yang D., Zhang X., Li T., Li J., Tang Y., Le W., Hypoxia-induced down-regulation of neprilysin by histone modification in mouse primary cortical and Hippocampal neurons PLoS ONE 2011 6 4
-
(2011)
PLoS ONE
, vol.6
, Issue.4
-
-
Wang, Z.1
Yang, D.2
Zhang, X.3
Li, T.4
Li, J.5
Tang, Y.6
Le, W.7
-
50
-
-
34547726181
-
A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord
-
Sun Y. G., Chen Z. F., A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord Nature 2007 448 7154 700 703
-
(2007)
Nature
, vol.448
, Issue.7154
, pp. 700-703
-
-
Sun, Y.G.1
Chen, Z.F.2
-
51
-
-
53249156551
-
Angiotensin-(17) and baroreflex function in nucleus tractus solitarii of (mRen2)27 transgenic rats
-
Diz D. I., Garcia-Espinosa M. A., Gallagher P. E., Ganten D., Ferrario C. M., Averill D. B., Angiotensin-(17) and baroreflex function in nucleus tractus solitarii of (mRen2)27 transgenic rats Journal of Cardiovascular Pharmacology 2008 51 6 542 548
-
(2008)
Journal of Cardiovascular Pharmacology
, vol.51
, Issue.6
, pp. 542-548
-
-
Diz, D.I.1
Garcia-Espinosa, M.A.2
Gallagher, P.E.3
Ganten, D.4
Ferrario, C.M.5
Averill, D.B.6
-
52
-
-
0036889596
-
Neuropeptide Y and its receptors as potential therapeutic drug targets
-
DOI 10.1016/S0009-8981(02)00301-7, PII S0009898102003017
-
Silva A. P., Cavadas C., Grouzmann E., Neuropeptide Y and its receptors as potential therapeutic drug targets Clinica Chimica Acta 2002 326 1-2 3 25 (Pubitemid 35341161)
-
(2002)
Clinica Chimica Acta
, vol.326
, Issue.1-2
, pp. 3-25
-
-
Silva, A.P.1
Cavadas, C.2
Grouzmann, E.3
-
53
-
-
66049148284
-
Stress influences brain enkephalinase, oxytocinase and angiotensinase activities: A new hypothesis
-
Hernndez J., Segarra A. B., Ramrez M., Banegas I., de Gasparo M., Alba F., Vives F., Durn R., Prieto I., Stress influences brain enkephalinase, oxytocinase and angiotensinase activities: a new hypothesis Neuropsychobiology 2009 59 3 184 189
-
(2009)
Neuropsychobiology
, vol.59
, Issue.3
, pp. 184-189
-
-
Hernndez, J.1
Segarra, A.B.2
Ramrez, M.3
Banegas, I.4
De Gasparo, M.5
Alba, F.6
Vives, F.7
Durn, R.8
Prieto, I.9
-
54
-
-
77049104041
-
Neurotensin promotes the dendrite elongation and the dendritic spine maturation of the cerebral cortex in vitro
-
Gandou C., Ohtani A., Senzaki K., Shiga T., Neurotensin promotes the dendrite elongation and the dendritic spine maturation of the cerebral cortex in vitro Neuroscience Research 2010 66 3 246 255
-
(2010)
Neuroscience Research
, vol.66
, Issue.3
, pp. 246-255
-
-
Gandou, C.1
Ohtani, A.2
Senzaki, K.3
Shiga, T.4
-
55
-
-
0037107556
-
Degradation of nociceptin (orphanin FQ) by mouse spinal cord synaptic membranes is triggered by endopeptidase-24.11: An in vitro and in vivo study
-
DOI 10.1016/S0006-2952(02)01295-9, PII S0006295202012959
-
Sakurada C., Sakurada S., Orito T., Tan-No K., Sakurada T., Degradation of nociceptin (orphanin FQ) by mouse spinal cord synaptic membranes is triggered by endopeptidase-24.11: an in vitro and in vivo study Biochemical Pharmacology 2002 64 8 1293 1303 (Pubitemid 35257922)
-
(2002)
Biochemical Pharmacology
, vol.64
, Issue.8
, pp. 1293-1303
-
-
Sakurada, C.1
Sakurada, S.2
Orito, T.3
Tan-No, K.4
Sakurada, T.5
-
56
-
-
78549278713
-
Changes in the activity of amyloid-degrading metallopeptidases leads to disruption of memory in rats
-
Dubrovskaya N. M., Nalivaeva N. N., Plesneva S. A., Feponova A. A., Turner A. J., Zhuravin I. A., Changes in the activity of amyloid-degrading metallopeptidases leads to disruption of memory in rats Neuroscience and Behavioral Physiology 2010 40 9 975 980
-
(2010)
Neuroscience and Behavioral Physiology
, vol.40
, Issue.9
, pp. 975-980
-
-
Dubrovskaya, N.M.1
Nalivaeva, N.N.2
Plesneva, S.A.3
Feponova, A.A.4
Turner, A.J.5
Zhuravin, I.A.6
-
57
-
-
84864928368
-
Mechanisms of short-term working memory deficit
-
New York, NY, USA Nova Science
-
Dubrovskaya N. M., Nalivaeva N. N., Vasilev D. S., Mechanisms of short-term working memory deficit Short-Term Memory: New Research 2012 New York, NY, USA Nova Science
-
(2012)
Short-Term Memory: New Research
-
-
Dubrovskaya, N.M.1
Nalivaeva, N.N.2
Vasilev, D.S.3
-
58
-
-
84859148674
-
Effect of sodium valproate administration on brain neprilysin expression and memory in rats
-
Nalivaeva N. N., Belyaev N. D., Lewis D. I., Pickles A. R., Makova N. Z., Bagrova D. I., Dubrovskaya N. M., Plesneva S. A., Zhuravin I. A., Turner A. J., Effect of sodium valproate administration on brain neprilysin expression and memory in rats Journal of Molecular Neuroscience 2012 46 3 569 577
-
(2012)
Journal of Molecular Neuroscience
, vol.46
, Issue.3
, pp. 569-577
-
-
Nalivaeva, N.N.1
Belyaev, N.D.2
Lewis, D.I.3
Pickles, A.R.4
Makova, N.Z.5
Bagrova, D.I.6
Dubrovskaya, N.M.7
Plesneva, S.A.8
Zhuravin, I.A.9
Turner, A.J.10
-
59
-
-
84864958911
-
Changes in the activity of amyloid-degrading enzymes affect cognitive functions in rats via alteration of the synaptopodin-positive dendritic network
-
Babusikova E. Dobrota D. Lehotsky J. Martin Slovakia
-
Nalivaeva N. N., Dubrovskaya N. M., Vasiliev D. S., Babusikova E., Dobrota D., Lehotsky J., Martin, Slovakia, Changes in the activity of amyloid-degrading enzymes affect cognitive functions in rats via alteration of the synaptopodin-positive dendritic network New Frontiers in Molecular Mechanisms in Neurological and Psychiatric Disorders 2011 1 277 285
-
(2011)
New Frontiers in Molecular Mechanisms in Neurological and Psychiatric Disorders
, vol.1
, pp. 277-285
-
-
Nalivaeva, N.N.1
Dubrovskaya, N.M.2
Vasiliev, D.S.3
-
60
-
-
79959876529
-
Epigenetic and pharmacological regulation of the amyloid-degrading enzyme neprilysin results in modulation of cognitive functions in mammals
-
Zhuravin I. A., Dubrovskaya N. M., Vasilev D. S., Tumanova N. L., Nalivaeva N. N., Epigenetic and pharmacological regulation of the amyloid-degrading enzyme neprilysin results in modulation of cognitive functions in mammals Doklady Biological Sciences 2011 438 1 145 148
-
(2011)
Doklady Biological Sciences
, vol.438
, Issue.1
, pp. 145-148
-
-
Zhuravin, I.A.1
Dubrovskaya, N.M.2
Vasilev, D.S.3
Tumanova, N.L.4
Nalivaeva, N.N.5
-
61
-
-
70549106846
-
Amyloid- as a positive endogenous regulator of release probability at hippocampal synapses
-
Abramov E., Dolev I., Fogel H., Ciccotosto G. D., Ruff E., Slutsky I., Amyloid- as a positive endogenous regulator of release probability at hippocampal synapses Nature Neuroscience 2009 12 12 1567 1576
-
(2009)
Nature Neuroscience
, vol.12
, Issue.12
, pp. 1567-1576
-
-
Abramov, E.1
Dolev, I.2
Fogel, H.3
Ciccotosto, G.D.4
Ruff, E.5
Slutsky, I.6
-
62
-
-
79960839801
-
Differential roles of calcitonin family peptides in the dendrite formation and spinogenesis of the cerebral cortex in vitro
-
Harigai Y., Natsume M., Li F., Ohtani A., Senzaki K., Shiga T., Differential roles of calcitonin family peptides in the dendrite formation and spinogenesis of the cerebral cortex in vitro Neuropeptides 2011 45 4 263 272
-
(2011)
Neuropeptides
, vol.45
, Issue.4
, pp. 263-272
-
-
Harigai, Y.1
Natsume, M.2
Li, F.3
Ohtani, A.4
Senzaki, K.5
Shiga, T.6
-
63
-
-
50449086487
-
Lack of adrenomedullin in the mouse brain results in behavioral changes, anxiety, and lower survival under stress conditions
-
Fernndez A. P., Serrano J., Tessarollo L., Cuttitta F., Martnez A., Lack of adrenomedullin in the mouse brain results in behavioral changes, anxiety, and lower survival under stress conditions Proceedings of the National Academy of Sciences of the United States of America 2008 105 34 12581 12586
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.34
, pp. 12581-12586
-
-
Fernndez, A.P.1
Serrano, J.2
Tessarollo, L.3
Cuttitta, F.4
Martnez, A.5
-
64
-
-
84655160769
-
Amyloid : Linking synaptic plasticity failure to memory disruption in Alzheimer's disease
-
Ma T., Klann E., Amyloid : linking synaptic plasticity failure to memory disruption in Alzheimer's disease Journal of Neurochemistry 2011 120 supplement 1 140 148
-
(2011)
Journal of Neurochemistry
, vol.120
, Issue.SUPPL. 1
, pp. 140-148
-
-
Ma, T.1
Klann, E.2
-
65
-
-
0036193784
-
Neutral endopeptidase knockout induces hyperalgesia in a model of visceral pain, an effect related to bradykinin and nitric oxide
-
DOI 10.1385/JMN:18:1-2:129
-
Fischer H. S., Zernig G., Hauser K. F., Gerard C., Hersh L. B., Saria A., Neutral endopeptidase knockout induces hyperalgesia in a model of visceral pain, an effect related to bradykinin and nitric oxide Journal of Molecular Neuroscience 2002 18 1-2 129 134 (Pubitemid 34252631)
-
(2002)
Journal of Molecular Neuroscience
, vol.18
, Issue.1-2
, pp. 129-134
-
-
Fischer, H.S.1
Zernig, G.2
Hauser, K.F.3
Gerard, C.4
Hersh, L.B.5
Saria, A.6
-
66
-
-
34249879822
-
Low dose of bradykinin selectively increases intracellular calcium in glioma cells
-
DOI 10.1016/j.jns.2007.02.031, PII S0022510X07001761
-
Wang Y. B., Peng C., Liu Y. H., Low dose of bradykinin selectively increases intracellular calcium in glioma cells Journal of the Neurological Sciences 2007 258 1-2 44 51 (Pubitemid 46874476)
-
(2007)
Journal of the Neurological Sciences
, vol.258
, Issue.1-2
, pp. 44-51
-
-
Wang, Y.-b.1
Peng, C.2
Liu, Y.-h.3
-
67
-
-
33751191841
-
Role of neuropeptides in appetite regulation and obesity - A review
-
DOI 10.1016/j.npep.2006.07.001, PII S0143417906000461
-
Arora S., Anubhuti, Role of neuropeptides in appetite regulation and obesitya review Neuropeptides 2006 40 6 375 401 (Pubitemid 44773748)
-
(2006)
Neuropeptides
, vol.40
, Issue.6
, pp. 375-401
-
-
Arora, S.1
Anubhuti2
-
68
-
-
28244454638
-
Altered expression of neprilysin family members in the pituitary gland of sleep-disturbed rats, an animal model of severe fatigue
-
DOI 10.1111/j.1471-4159.2005.03436.x
-
Ogawa T., Kiryu-Seo S., Tanaka M., Konishi H., Iwata N., Saido T., Watanabe Y., Kiyama H., Altered expression of neprilysin family members in the pituitary gland of sleep-disturbed rats, an animal model of severe fatigue Journal of Neurochemistry 2005 95 4 1156 1166 (Pubitemid 41713498)
-
(2005)
Journal of Neurochemistry
, vol.95
, Issue.4
, pp. 1156-1166
-
-
Ogawa, T.1
Kiryu-Seo, S.2
Tanaka, M.3
Konishi, H.4
Iwata, N.5
Saido, T.6
Watanabe, Y.7
Kiyama, H.8
-
69
-
-
67849101645
-
30 years of dynorphinsnew insights on their functions in neuropsychiatric diseases
-
Schwarzer C., 30 years of dynorphinsnew insights on their functions in neuropsychiatric diseases Pharmacology and Therapeutics 2009 123 3 353 370
-
(2009)
Pharmacology and Therapeutics
, vol.123
, Issue.3
, pp. 353-370
-
-
Schwarzer, C.1
-
70
-
-
0037336859
-
Peptidases prevent μ-opioid receptor internalization in dorsal horn neurons by endogenously released opioids
-
Song B., Marvizn J. C. G., Peptidases prevent -opioid receptor internalization in dorsal horn neurons by endogenously released opioids Journal of Neuroscience 2003 23 5 1847 1858 (Pubitemid 36314740)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.5
, pp. 1847-1858
-
-
Song, B.1
Marvizon, J.C.G.2
-
71
-
-
0027475050
-
Neutral endopeptidase 24.11: Structure, inhibition, and experimental and clinical pharmacology
-
Roques B. P., Noble F., Daugé V., Fournie-Zaluski M. C., Beaumont A., Neutral endopeptidase 24.11: structure, inhibition, and experimental and clinical pharmacology Pharmacological Reviews 1993 45 1 87 146 (Pubitemid 23108243)
-
(1993)
Pharmacological Reviews
, vol.45
, Issue.1
, pp. 87-146
-
-
Roques, B.P.1
Noble, F.2
Dauge, V.3
Fournie-Zaluski, M.-C.4
Beaumont, A.5
-
72
-
-
79958701063
-
Nitric oxide production by endothelin-1 enhances astrocytic migration via the tyrosine nitration of matrix metalloproteinase-9
-
Wang H. H., Hsieh H. L., Yang C. M., Nitric oxide production by endothelin-1 enhances astrocytic migration via the tyrosine nitration of matrix metalloproteinase-9 Journal of Cellular Physiology 2011 226 9 2244 2256
-
(2011)
Journal of Cellular Physiology
, vol.226
, Issue.9
, pp. 2244-2256
-
-
Wang, H.H.1
Hsieh, H.L.2
Yang, C.M.3
-
73
-
-
79953282984
-
Gastrin-releasing peptide modulates fast delayed rectifier potassium current in Per1-expressing SCN neurons
-
Gamble K. L., Kudo T., Colwell C. S., McMahon D. G., Gastrin-releasing peptide modulates fast delayed rectifier potassium current in Per1-expressing SCN neurons Journal of Biological Rhythms 2011 26 2 99 106
-
(2011)
Journal of Biological Rhythms
, vol.26
, Issue.2
, pp. 99-106
-
-
Gamble, K.L.1
Kudo, T.2
Colwell, C.S.3
McMahon, D.G.4
-
74
-
-
43549112903
-
Somatostatinergic systems in brain: Networks and functions
-
DOI 10.1016/j.mce.2007.09.007, PII S0303720707003462
-
Viollet C., Lepousez G., Loudes C., Videau C., Simon A., Epelbaum J., Somatostatinergic systems in brain: networks and functions Molecular and Cellular Endocrinology 2008 286 1-2 75 87 (Pubitemid 351680238)
-
(2008)
Molecular and Cellular Endocrinology
, vol.286
, Issue.1-2
, pp. 75-87
-
-
Viollet, C.1
Lepousez, G.2
Loudes, C.3
Videau, C.4
Simon, A.5
Epelbaum, J.6
-
75
-
-
67649460578
-
Increased pain and neurogenic inflammation in mice deficient of neutral endopeptidase
-
Krmer H. H., He L., Lu B., Birklein F., Sommer C., Increased pain and neurogenic inflammation in mice deficient of neutral endopeptidase Neurobiology of Disease 2009 35 2 177 183
-
(2009)
Neurobiology of Disease
, vol.35
, Issue.2
, pp. 177-183
-
-
Krmer, H.H.1
He, L.2
Lu, B.3
Birklein, F.4
Sommer, C.5
-
76
-
-
0037498424
-
Substance P and cholecystokinin regulate neurochemical responses to cocaine and methamphetamine in the striatum
-
DOI 10.1016/S0024-3205(03)00393-X
-
Loonam T. M., Noailles P. A. H., Yu J., Zhu J. P. Q., Angulo J. A., Substance P and cholecystokinin regulate neurochemical responses to cocaine and methamphetamine in the striatum Life Sciences 2003 73 6 727 739 (Pubitemid 36703267)
-
(2003)
Life Sciences
, vol.73
, Issue.6
, pp. 727-739
-
-
Loonam, T.M.1
Noailles, P.A.H.2
Yu, J.3
Zhu, J.P.Q.4
Angulo, J.A.5
-
77
-
-
0027213668
-
Sequence-specific effects of neurokinin substance P on memory, reinforcement, and brain dopamine activity
-
Huston J. P., Hasenhrl R. U., Boix F., Gerhardt P., Schwarting R. K. W., Sequence-specific effects of neurokinin substance P on memory, reinforcement, and brain dopamine activity Psychopharmacology 1993 112 2-3 147 162 (Pubitemid 23278274)
-
(1993)
Psychopharmacology
, vol.112
, Issue.2-3
, pp. 147-162
-
-
Huston, J.P.1
Hasenohrl, R.U.2
Boix, F.3
Gerhardt, P.4
Schwarting, R.K.W.5
-
78
-
-
0033753176
-
Substance P and its role in neural mechanisms governing learning, anxiety and functional recovery
-
Hasenhrl R. U., Souza-Silva M. A. D., Nikolaus S., Tomaz C., Brandao M. L., Schwarting R. K. W., Huston J. P., Substance P and its role in neural mechanisms governing learning, anxiety and functional recovery Neuropeptides 2000 34 5 272 280
-
(2000)
Neuropeptides
, vol.34
, Issue.5
, pp. 272-280
-
-
Hasenhrl, R.U.1
Souza-Silva, M.A.D.2
Nikolaus, S.3
Tomaz, C.4
Brandao, M.L.5
Schwarting, R.K.W.6
Huston, J.P.7
-
79
-
-
18844402614
-
1 receptor have a role in depression and anxiety?
-
DOI 10.2174/1381612053764779
-
McLean S., Do substance P and the NK1 receptor have a role in depression and anxiety? Current Pharmaceutical Design 2005 11 12 1529 1547 (Pubitemid 40691450)
-
(2005)
Current Pharmaceutical Design
, vol.11
, Issue.12
, pp. 1529-1547
-
-
McLean, S.1
-
80
-
-
34548511354
-
Rapid changes in substance P signaling and neutral endopeptidase induced by skin-scratching stimulation in mice
-
DOI 10.1016/j.jdermsci.2007.06.007, PII S0923181107002228
-
Yamaoka J., Kawana S., Rapid changes in substance P signaling and neutral endopeptidase induced by skin-scratching stimulation in mice Journal of Dermatological Science 2007 48 2 123 132 (Pubitemid 47380250)
-
(2007)
Journal of Dermatological Science
, vol.48
, Issue.2
, pp. 123-132
-
-
Yamaoka, J.1
Kawana, S.2
-
81
-
-
79955704709
-
Neuropeptide signaling differentially affects phase maintenance and rhythm generation in SCN and extra-SCN circadian oscillators
-
Hughes A. T. L., Guilding C., Piggins H. D., Neuropeptide signaling differentially affects phase maintenance and rhythm generation in SCN and extra-SCN circadian oscillators PLoS ONE 2011 6 4
-
(2011)
PLoS ONE
, vol.6
, Issue.4
-
-
Hughes, A.T.L.1
Guilding, C.2
Piggins, H.D.3
-
82
-
-
0029061685
-
Neutral endopeptidase can hydrolyze -amyloid(140) but shows no effect on -amyloid precursor protein metabolism
-
Howell S., Nalbantoglu J., Crine P., Neutral endopeptidase can hydrolyze -amyloid(140) but shows no effect on -amyloid precursor protein metabolism Peptides 1995 16 4 647 652
-
(1995)
Peptides
, vol.16
, Issue.4
, pp. 647-652
-
-
Howell, S.1
Nalbantoglu, J.2
Crine, P.3
-
83
-
-
0033621739
-
1-42-degrading catabolic pathway in brain parenchyma: Suppression leads to biochemical and pathological deposition
-
DOI 10.1038/72237
-
Iwata N., Tsubuki S., Takaki Y., Watanabe K., Sekiguchi M., Hosoki E., Kawashima-Morishima M., Lee H. J., Hama E., Sekine-Aizawa Y., Saido T. C., Identification of the major A 142-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition Nature Medicine 2000 6 2 143 150 (Pubitemid 30082357)
-
(2000)
Nature Medicine
, vol.6
, Issue.2
, pp. 143-150
-
-
Iwata, N.1
Tsubuki, S.2
Takaki, Y.3
Watanabe, K.4
Sekiguchi, M.5
Hosoki, E.6
Kawashima-Morishima, M.7
Lee, H.-J.8
Hama, E.9
Sekine-Aizawa, Y.10
Saido, T.C.11
-
84
-
-
0034530036
-
Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid β peptide in the brain
-
Takaki Y., Iwata N., Tsubuki S., Taniguchi S., Toyoshima S., Lu B., Gerard N. P., Gerard C., Lee H. J., Shirotani K., Saido T. C., Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid peptide in the brain Journal of Biochemistry 2000 128 6 897 902 (Pubitemid 32011559)
-
(2000)
Journal of Biochemistry
, vol.128
, Issue.6
, pp. 897-902
-
-
Takaki, Y.1
Iwata, N.2
Tsubuki, S.3
Taniguchi, S.4
Toyoshima, S.5
Lu, B.6
Gerard, N.P.7
Gerard, C.8
Lee, H.-J.9
Shirotani, K.10
Saido, T.C.11
-
85
-
-
0035947207
-
Metabolic regulation of brain A by neprilysin
-
Iwata N., Tsubuki S., Takaki Y., Shirotani K., Lu B., Gerard N. P., Gerard C., Hama E., Lee H. J., Saido T. C., Metabolic regulation of brain A by neprilysin Science 2001 292 5521 1550 1552
-
(2001)
Science
, vol.292
, Issue.5521
, pp. 1550-1552
-
-
Iwata, N.1
Tsubuki, S.2
Takaki, Y.3
Shirotani, K.4
Lu, B.5
Gerard, N.P.6
Gerard, C.7
Hama, E.8
Lee, H.J.9
Saido, T.C.10
-
86
-
-
0035659917
-
Clearance of extracellular and cell-associated amyloid β peptide through viral expression of neprilysin in primary neurons
-
Hama E., Shirotani K., Masumoto H., Sekine-Aizawa Y., Aizawa H., Saido T. C., Clearance of extracellular and cell-associated amyloid peptide through viral expression of neprilysin in primary neurons Journal of Biochemistry 2001 130 6 721 726 (Pubitemid 34024119)
-
(2001)
Journal of Biochemistry
, vol.130
, Issue.6
, pp. 721-726
-
-
Hama, E.1
Shirotani, K.2
Masumoto, H.3
Sekine-Aizawa, Y.4
Aizawa, H.5
Saido, T.C.6
-
87
-
-
0037444432
-
Neprilysin gene transfer reduces human amyloid pathology in transgenic mice
-
Marr R. A., Rockenstein E., Mukherjee A., Kindy M. S., Hersh L. B., Gage F. H., Verma I. M., Masliah E., Neprilysin gene transfer reduces human amyloid pathology in transgenic mice Journal of Neuroscience 2003 23 6 1992 1996 (Pubitemid 36368884)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.6
, pp. 1992-1996
-
-
Marr, R.A.1
Rockenstein, E.2
Mukherjee, A.3
Kindy, M.S.4
Hersh, L.B.5
Gage, F.H.6
Verma, I.M.7
Masliah, E.8
-
88
-
-
57449117668
-
Long-term neprilysin gene transfer is associated with reduced levels of intracellular A and behavioral improvement in APP transgenic mice
-
Spencer B., Marr R. A., Rockenstein E., Crews L., Adame A., Potkar R., Patrick C., Gage F. H., Verma I. M., Masliah E., Long-term neprilysin gene transfer is associated with reduced levels of intracellular A and behavioral improvement in APP transgenic mice BMC Neuroscience 2008 9, article 109
-
(2008)
BMC Neuroscience
, vol.9109
-
-
Spencer, B.1
Marr, R.A.2
Rockenstein, E.3
Crews, L.4
Adame, A.5
Potkar, R.6
Patrick, C.7
Gage, F.H.8
Verma, I.M.9
Masliah, E.10
-
89
-
-
0035877747
-
Neprilysin degrades both amyloid peptides 140 and 142 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases
-
Shirotani K., Tsubuki S., Iwata N., Takaki Y., Harigaya W., Maruyama K., Kiryu-Seo S., Kiyama H., Iwata H., Tomita T., Iwatsubo T., Saido T. C., Neprilysin degrades both amyloid peptides 140 and 142 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases The Journal of Biological Chemistry 2001 276 24 21895 21901
-
(2001)
The Journal of Biological Chemistry
, vol.276
, Issue.24
, pp. 21895-21901
-
-
Shirotani, K.1
Tsubuki, S.2
Iwata, N.3
Takaki, Y.4
Harigaya, W.5
Maruyama, K.6
Kiryu-Seo, S.7
Kiyama, H.8
Iwata, H.9
Tomita, T.10
Iwatsubo, T.11
Saido, T.C.12
-
90
-
-
0042827324
-
Human neprilysin is capable of degrading amyloid β peptide not only in the monomeric form but also the pathological oligomeric form
-
DOI 10.1016/S0304-3940(03)00898-X
-
Kanemitsu H., Tomiyama T., Mori H., Human neprilysin is capable of degrading amyloid peptide not only in the monomeric form but also the pathological oligomeric form Neuroscience Letters 2003 350 2 113 116 (Pubitemid 37101425)
-
(2003)
Neuroscience Letters
, vol.350
, Issue.2
, pp. 113-116
-
-
Kanemitsu, H.1
Tomiyama, T.2
Mori, H.3
-
91
-
-
80655144756
-
Pyroglutamate amyloid- (A ): A hatchet man in Alzheimer disease
-
Jawhar S., Wirths O., Bayer T. A., Pyroglutamate amyloid- (A ): a hatchet man in Alzheimer disease The Journal of Biological Chemistry 2011 286 45 38825 38832
-
(2011)
The Journal of Biological Chemistry
, vol.286
, Issue.45
, pp. 38825-38832
-
-
Jawhar, S.1
Wirths, O.2
Bayer, T.A.3
-
92
-
-
78651247095
-
Alzheimer's A peptides with disease-associated NTerminal modifications: Influence of isomerisation, truncation and mutation on Cu 2+ coordination
-
Drew S. C., Masters C. L., Barnham K. J., Alzheimer's A peptides with disease-associated NTerminal modifications: Influence of isomerisation, truncation and mutation on Cu 2+ coordination PLoS ONE 2010 5 12
-
(2010)
PLoS ONE
, vol.5
, Issue.12
-
-
Drew, S.C.1
Masters, C.L.2
Barnham, K.J.3
-
93
-
-
14944380978
-
Effect of hypoxia/ischemia and hypoxic preconditioning/reperfusion on expression of some amyloid-degrading enzymes
-
DOI 10.1196/annals.1332.002
-
Nalivaeva N. N., Fisk L., Kochkina E. G., Plesneva S. A., Zhuravin I. A., Babusikova E., Dobrota D., Turner A. J., Effect of hypoxia/ischemia and hypoxic preconditioning/reperfusion on expression of some amyloid-degrading enzymes Annals of the New York Academy of Sciences 2004 1035 21 33 (Pubitemid 40362324)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1035
, pp. 21-33
-
-
Nalivaeva, N.N.1
Fisk, L.2
Kochkina, E.G.3
Plesneva, S.A.4
Zhuravin, I.A.5
Babusikova, E.6
Dobrota, D.7
Turner, A.J.8
-
94
-
-
13644266898
-
Age- and region-dependent alterations in Aβ-degrading enzymes: Implications for Aβ-induced disorders
-
DOI 10.1016/j.neurobiolaging.2004.06.013
-
Caccamo A., Oddo S., Sugarman M. C., Akbari Y., LaFerla F. M., Age- and region-dependent alterations in A -degrading enzymes: implications for A -induced disorders Neurobiology of Aging 2005 26 5 645 654 (Pubitemid 40228756)
-
(2005)
Neurobiology of Aging
, vol.26
, Issue.5
, pp. 645-654
-
-
Caccamo, A.1
Oddo, S.2
Sugarman, M.C.3
Akbari, Y.4
LaFerla, F.M.5
-
95
-
-
20944435413
-
Decreased neprilysin immunoreactivity in Alzheimer disease, but not in pathological aging
-
Wang D. S., Lipton R. B., Katz M. J., Davies P., Buschke H., Kuslansky G., Verghese J., Younkin S. G., Eckman C., Dickson D. W., Decreased neprilysin immunoreactivity in Alzheimer disease, but not in pathological aging Journal of Neuropathology and Experimental Neurology 2005 64 5 378 385 (Pubitemid 40629127)
-
(2005)
Journal of Neuropathology and Experimental Neurology
, vol.64
, Issue.5
, pp. 378-385
-
-
Wang, D.-S.1
Lipton, R.B.2
Katz, M.J.3
Davies, P.4
Buschke, H.5
Kuslansky, G.6
Verghese, J.7
Younkin, S.G.8
Eckman, C.9
Dickson, D.W.10
-
96
-
-
0036794008
-
Declining expression of neprilysin in Alzheimer disease vasculature: Possible involvement in cerebral amyloid angiopathy
-
Carpentier M., Robitaille Y., DesGroseillers L., Boileau G., Marcinkiewicz M., Declining expression of neprilysin in Alzheimer disease vasculature: possible involvement in cerebral amyloid angiopathy Journal of Neuropathology and Experimental Neurology 2002 61 10 849 856
-
(2002)
Journal of Neuropathology and Experimental Neurology
, vol.61
, Issue.10
, pp. 849-856
-
-
Carpentier, M.1
Robitaille, Y.2
Desgroseillers, L.3
Boileau, G.4
Marcinkiewicz, M.5
-
97
-
-
0037468588
-
Aging-related down-regulation of neprilysin, a putative β-amyloid-degrading enzyme, in transgenic Tg2576 Alzheimer-like mouse brain is accompanied by an astroglial upregulation in the vicinity of β-amyloid plaques
-
DOI 10.1016/S0304-3940(03)00030-2
-
Apelt J., Ach K., Schliebs R., Aging-related down-regulation of neprilysin, a putative -amyloid-degrading enzyme, in transgenic Tg2576 Alzheimer-like mouse brain is accompanied by an astroglial upregulation in the vicinity of -amyloid plaques Neuroscience Letters 2003 339 3 183 186 (Pubitemid 36298997)
-
(2003)
Neuroscience Letters
, vol.339
, Issue.3
, pp. 183-186
-
-
Apelt, J.1
Ach, K.2
Schliebs, R.3
-
98
-
-
0141514419
-
Oxidized neprilysin in aging and Alzheimer's disease brains
-
DOI 10.1016/j.bbrc.2003.09.003
-
Wang D. S., Iwata N., Hama E., Saido T. C., Dickson D. W., Oxidized neprilysin in aging and Alzheimer's disease brains Biochemical and Biophysical Research Communications 2003 310 1 236 241 (Pubitemid 37162788)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.310
, Issue.1
, pp. 236-241
-
-
Wang, D.-S.1
Iwata, N.2
Hama, E.3
Saido, T.C.4
Dickson, D.W.5
-
99
-
-
77955846215
-
Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's disease
-
Dorfman V. B., Pasquini L., Riudavets M., Lpez-Costa J. J., Villegas A., Troncoso J. C., Lopera F., Castao E. M., Morelli L., Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's disease Neurobiology of Aging 2010 31 10 1743 1757
-
(2010)
Neurobiology of Aging
, vol.31
, Issue.10
, pp. 1743-1757
-
-
Dorfman, V.B.1
Pasquini, L.2
Riudavets, M.3
Lpez-Costa, J.J.4
Villegas, A.5
Troncoso, J.C.6
Lopera, F.7
Castao, E.M.8
Morelli, L.9
-
100
-
-
0034685637
-
Neprilysin II: A putative novel metalloprotease and its isoforms in CNS and testis
-
DOI 10.1006/bbrc.2000.2664
-
Tanja O., Facchinetti P., Rose C., Bonhomme M. C., Gros C., Schwartz J. C., Neprilysin II: a putative novel metalloprotease and its isoforms in CNS and testis Biochemical and Biophysical Research Communications 2000 271 3 565 570 (Pubitemid 30444668)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.271
, Issue.3
, pp. 565-570
-
-
Tanja, O.1
Facchinetti, P.2
Rose, C.3
Bonhomme, M.-C.4
Gros, C.5
Schwartz, J.-C.6
-
101
-
-
0033527579
-
Molecular identification and characterization of novel membrane-bound metalloprotease, the soluble secreted form of which hydrolyzes a variety of vasoactive peptides
-
Ikeda K., Emoto N., Raharjo S. B., Nurhantari Y., Saiki K., Yokoyama M., Matsuo M., Molecular identification and characterization of novel membrane-bound metalloprotease, the soluble secreted form of which hydrolyzes a variety of vasoactive peptides The Journal of Biological Chemistry 1999 274 45 32469 32477
-
(1999)
The Journal of Biological Chemistry
, vol.274
, Issue.45
, pp. 32469-32477
-
-
Ikeda, K.1
Emoto, N.2
Raharjo, S.B.3
Nurhantari, Y.4
Saiki, K.5
Yokoyama, M.6
Matsuo, M.7
-
102
-
-
0037466757
-
Ontogeny, regional and cellular distribution of the novel metalloprotease neprilysin 2 in the rat: A comparison with neprilysin and endothelin-converting enzyme-1
-
DOI 10.1016/S0306-4522(02)01002-3
-
Facchinetti P., Rose C., Schwartz J. C., Ouimet T., Ontogeny, regional and cellular distribution of the novel metalloprotease neprilysin 2 in the rat: a comparison with neprilysin and endothelin-converting enzyme-1 Neuroscience 2003 118 3 627 639 (Pubitemid 36506952)
-
(2003)
Neuroscience
, vol.118
, Issue.3
, pp. 627-639
-
-
Facchinetti, P.1
Rose, C.2
Schwartz, J.C.3
Ouimet, T.4
-
103
-
-
47249153453
-
Human membrane metallo-endopeptidase-like protein degrades both -amyloid 42 and -amyloid 40
-
Huang J. Y., Bruno A. M., Patel C. A., Huynh A. M., Philibert K. D., Glucksman M. J., Marr R. A., Human membrane metallo-endopeptidase-like protein degrades both -amyloid 42 and -amyloid 40 Neuroscience 2008 155 1 258 262
-
(2008)
Neuroscience
, vol.155
, Issue.1
, pp. 258-262
-
-
Huang, J.Y.1
Bruno, A.M.2
Patel, C.A.3
Huynh, A.M.4
Philibert, K.D.5
Glucksman, M.J.6
Marr, R.A.7
-
104
-
-
79251469086
-
Neprilysin-2 is an important -amyloid degrading enzyme
-
Hafez D., Huang J. Y., Huynh A. M., Valtierra S., Rockenstein E., Bruno A. M., Lu B., DesGroseillers L., Masliah E., Marr R. A., Neprilysin-2 is an important -amyloid degrading enzyme American Journal of Pathology 2011 178 1 306 312
-
(2011)
American Journal of Pathology
, vol.178
, Issue.1
, pp. 306-312
-
-
Hafez, D.1
Huang, J.Y.2
Huynh, A.M.3
Valtierra, S.4
Rockenstein, E.5
Bruno, A.M.6
Lu, B.7
Desgroseillers, L.8
Masliah, E.9
Marr, R.A.10
-
105
-
-
84863046521
-
Altered NEP2 expression and activity in mild cognitive impairment and Alzheimer's disease
-
Huang J. Y., Hafez D. M., James B. D., Altered NEP2 expression and activity in mild cognitive impairment and Alzheimer's disease Journal of Alzheimer's Disease 2012 28 2 433 441
-
(2012)
Journal of Alzheimer's Disease
, vol.28
, Issue.2
, pp. 433-441
-
-
Huang, J.Y.1
Hafez, D.M.2
James, B.D.3
-
106
-
-
79551635864
-
Peripheral delivery of a CNS targeted, metalo-protease reduces A toxicity in a mouse model of Alzheimer's disease
-
Spencer B., Marr R. A., Gindi R., Potkar R., Michael S., Adame A., Rockenstein E., Verma I. M., Masliah E., Peripheral delivery of a CNS targeted, metalo-protease reduces A toxicity in a mouse model of Alzheimer's disease PLoS ONE 2011 6 1
-
(2011)
PLoS ONE
, vol.6
, Issue.1
-
-
Spencer, B.1
Marr, R.A.2
Gindi, R.3
Potkar, R.4
Michael, S.5
Adame, A.6
Rockenstein, E.7
Verma, I.M.8
Masliah, E.9
-
107
-
-
78049382779
-
A novel system for in vivo neprilysin gene delivery using a syringe electrode
-
Li Y., Wang J., Liu J., Liu F., A novel system for in vivo neprilysin gene delivery using a syringe electrode Journal of Neuroscience Methods 2010 193 2 226 231
-
(2010)
Journal of Neuroscience Methods
, vol.193
, Issue.2
, pp. 226-231
-
-
Li, Y.1
Wang, J.2
Liu, J.3
Liu, F.4
-
108
-
-
34548456959
-
Reducing amyloid plaque burden via ex vivo gene delivery of an A -degrading protease: A novel therapeutic approach to Alzheimer disease
-
ARTICLE E262
-
Hemming M. L., Patterson M., Reske-Nielsen C., Lin L., Isacson O., Selkoe D. J., Reducing amyloid plaque burden via ex vivo gene delivery of an A -degrading protease: a novel therapeutic approach to Alzheimer disease PLoS Medicine 2007 4 8, article e262
-
(2007)
PLoS Medicine
, vol.4
, Issue.8
-
-
Hemming, M.L.1
Patterson, M.2
Reske-Nielsen, C.3
Lin, L.4
Isacson, O.5
Selkoe, D.J.6
-
109
-
-
7644225312
-
RAGE (Yin) versus LRP (Yang) balance regulates Alzheimer amyloid β-peptide clearance through transport across the blood-brain barrier
-
DOI 10.1161/01.STR.0000143452.85382.d1
-
Deane R., Wu Z., Zlokovic B. V., RAGE (Yin) versus LRP (Yang) balance regulates Alzheimer amyloid -peptide clearance through transport across the blood-brain barrier Stroke 2004 35 11 2628 2631 (Pubitemid 39458354)
-
(2004)
Stroke
, vol.35
, Issue.11 SUPPL. 1
, pp. 2628-2631
-
-
Deane, R.1
Wu, Z.2
Zlokovic, B.V.3
-
110
-
-
36148979336
-
In vitro and in vivo degradation of Aβ peptide by peptidases coupled to erythrocytes
-
DOI 10.1016/j.peptides.2007.09.015, PII S0196978107003932
-
Liu Y., Guan H., Beckett T. L., Juliano M. A., Juliano L., Song E. S., Chow K. M., Murphy M. P., Hersh L. B., In vitro and in vivo degradation of A peptide by peptidases coupled to erythrocytes Peptides 2007 28 12 2348 2355 (Pubitemid 350116309)
-
(2007)
Peptides
, vol.28
, Issue.12
, pp. 2348-2355
-
-
Liu, Y.1
Guan, H.2
Beckett, T.L.3
Juliano, M.A.4
Juliano, L.5
Song, E.S.6
Chow, K.M.7
Murphy, M.P.8
Hersh, L.B.9
-
111
-
-
65549114145
-
Peripherally expressed neprilysin reduces brain amyloid burden: A novel approach for treating Alzheimer's disease
-
Guan H., Liu Y., Daily A., Police S., Kim M. H., Oddo S., LaFerla F. M., Pauly J. R., Murphy M. P., Hersh L. B., Peripherally expressed neprilysin reduces brain amyloid burden: a novel approach for treating Alzheimer's disease Journal of Neuroscience Research 2009 87 6 1462 1473
-
(2009)
Journal of Neuroscience Research
, vol.87
, Issue.6
, pp. 1462-1473
-
-
Guan, H.1
Liu, Y.2
Daily, A.3
Police, S.4
Kim, M.H.5
Oddo, S.6
Laferla, F.M.7
Pauly, J.R.8
Murphy, M.P.9
Hersh, L.B.10
-
112
-
-
77955773499
-
Circulating neprilysin clears brain amyloid
-
Liu Y., Studzinski C., Beckett T., Murphy M. P., Klein R. L., Hersh L. B., Circulating neprilysin clears brain amyloid Molecular and Cellular Neuroscience 2010 45 2 101 107
-
(2010)
Molecular and Cellular Neuroscience
, vol.45
, Issue.2
, pp. 101-107
-
-
Liu, Y.1
Studzinski, C.2
Beckett, T.3
Murphy, M.P.4
Klein, R.L.5
Hersh, L.B.6
-
113
-
-
43449092187
-
Neprilysin: An enzyme candidate to slow the progression of Alzheimer's disease
-
DOI 10.2353/ajpath.2008.070620
-
El-Amouri S. S., Zhu H., Yu J., Marr R., Verma I. M., Kindy M. S., Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease American Journal of Pathology 2008 172 5 1342 1354 (Pubitemid 351671547)
-
(2008)
American Journal of Pathology
, vol.172
, Issue.5
, pp. 1342-1354
-
-
El-Amouri, S.S.1
Zhu, H.2
Yu, J.3
Marr, R.4
Verma, I.M.5
Kindy, M.S.6
-
114
-
-
0041837636
-
Enhancement of neutral endopeptidase activity in SK-N-SH cells by green tea extract
-
DOI 10.1078/094471103322331449
-
Melzig M. F., Janka M., Enhancement of neutral endopeptidase activity in SK-N-SH cells by green tea extract Phytomedicine 2003 10 6-7 494 498 (Pubitemid 37092672)
-
(2003)
Phytomedicine
, vol.10
, Issue.6-7
, pp. 494-498
-
-
Melzig, M.F.1
Janka, M.2
-
115
-
-
31144443418
-
Effect of Epilobium angustifolium L. extracts and polyphenols on cell proliferation and neutral endopeptidase activity in selected cell lines
-
Kiss A., Kowalski J., Melzig M. F., Effect of Epilobium angustifolium L. extracts and polyphenols on cell proliferation and neutral endopeptidase activity in selected cell lines Pharmazie 2006 61 1 66 69 (Pubitemid 43128779)
-
(2006)
Pharmazie
, vol.61
, Issue.1
, pp. 66-69
-
-
Kiss, A.1
Kowalski, J.2
Melzig, M.F.3
-
116
-
-
17644425569
-
42 through modulation of proteolytic degradation
-
DOI 10.1038/nm1206
-
Sito T., Iwata N., Tsubuki S., Takaki Y., Takano J., Huang S. M., Suemoto T., Higuchi M., Saido T. C., Somatostatin regulates brain amyloid peptide A 42 through modulation of proteolytic degradation Nature Medicine 2005 11 4 434 439 (Pubitemid 40562335)
-
(2005)
Nature Medicine
, vol.11
, Issue.4
, pp. 434-439
-
-
Saito, T.1
Iwata, N.2
Tsubuki, S.3
Takaki, Y.4
Takano, J.5
Huang, S.-M.6
Suemoto, T.7
Higuchi, M.8
Saido, T.C.9
-
117
-
-
79251577369
-
A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice
-
Niikura T., Sidahmed E., Hirata-Fukae C., Aisen P. S., Matsuoka Y., A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice PLoS ONE 2011 6 1
-
(2011)
PLoS ONE
, vol.6
, Issue.1
-
-
Niikura, T.1
Sidahmed, E.2
Hirata-Fukae, C.3
Aisen, P.S.4
Matsuoka, Y.5
-
118
-
-
70249113348
-
A PPARdelta agonist reduces amyloid burden and brain inflammation in a transgenic mouse model of Alzheimer's disease
-
Kalinin S., Richardson J. C., Feinstein D. L., A PPARdelta agonist reduces amyloid burden and brain inflammation in a transgenic mouse model of Alzheimer's disease Current Alzheimer Research 2009 6 5 431 437
-
(2009)
Current Alzheimer Research
, vol.6
, Issue.5
, pp. 431-437
-
-
Kalinin, S.1
Richardson, J.C.2
Feinstein, D.L.3
-
119
-
-
20444398562
-
Presenilin-dependent transcriptional control of the Aβ-degrading enzyme neprilysin by intracellular domains of βAPP and APLP
-
DOI 10.1016/j.neuron.2005.04.008, PII S0896627305003211
-
Pardossi-Piquard R., Petit A., Kawarai T., Sunyach C., Da Costa C. A., Vincent B., Ring S., D'Adamio L., Shen J., Mller U., Hyslop P. S. G., Checler F., Presenilin-dependent transcriptional control of the A -degrading enzyme neprilysin by intracellular domains of APP and APLP Neuron 2005 46 4 541 554 (Pubitemid 40797380)
-
(2005)
Neuron
, vol.46
, Issue.4
, pp. 541-554
-
-
Pardossi-Piquard, R.1
Petit, A.2
Kawarai, T.3
Sunyach, C.4
Da Costa, C.A.5
Vincent, B.6
Ring, S.7
D'Adamio, L.8
Shen, J.9
Muller, U.10
Hyslop, P.St.G.11
Checler, F.12
-
120
-
-
0035941278
-
Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment : Evidence for distinct mechanisms involved in -secretase processing of the APP and Notch1 transmembrane domains
-
Yu C., Kim S. H., Ikeuchi T., Xu H., Gasparini L., Wang R., Sisodia S. S., Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment : evidence for distinct mechanisms involved in -secretase processing of the APP and Notch1 transmembrane domains The Journal of Biological Chemistry 2001 276 47 43756 43760
-
(2001)
The Journal of Biological Chemistry
, vol.276
, Issue.47
, pp. 43756-43760
-
-
Yu, C.1
Kim, S.H.2
Ikeuchi, T.3
Xu, H.4
Gasparini, L.5
Wang, R.6
Sisodia, S.S.7
-
121
-
-
0041589353
-
Potential Link between Amyloid β-Protein 42 and C-terminal Fragment γ 49-99 of β-Amyloid Precursor Protein
-
DOI 10.1074/jbc.M211161200
-
Sato T., Dohmae N., Qi Y., Kakuda N., Misonou H., Mitsumori R., Maruyama H., Koo E. H., Haass C., Takio K., Morishima-Kawashima M., Ishiura S., Ihara Y., Potential link between amyloid -protein 42 and C-terminal fragment 4999 of -amyloid precursor protein The Journal of Biological Chemistry 2003 278 27 24294 20301 (Pubitemid 37548579)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.27
, pp. 24294-20301
-
-
Sato, T.1
Dohmae, N.2
Qi, Y.3
Kakuda, N.4
Misonou, H.5
Mitsumori, R.6
Maruyama, H.7
Koo, E.H.8
Haass, C.9
Takio, K.10
Morishima-Kawashima, M.11
Ishiura, S.12
Ihara, Y.13
-
122
-
-
33846807664
-
Response to: Pardossi-Piquard etal., "Presenilin-Dependent Transcriptional Control of the Aβ-Degrading Enzyme Neprilysin by Intracellular Domains of βAPP and APLP." Neuron 46, 541-554
-
DOI 10.1016/j.neuron.2007.01.023, PII S0896627307000645
-
Chen A. C., Selkoe D. J., Response to: Pardossi-Piquard etal., Presenilin-dependent transcriptional control of the A -degrading enzyme neprilysin by intracellular domains of APP and APLP. Neuron 46, 541554 Neuron 2007 53 4 479 483 (Pubitemid 46216754)
-
(2007)
Neuron
, vol.53
, Issue.4
, pp. 479-483
-
-
Chen, A.C.1
Selkoe, D.J.2
-
123
-
-
33745584643
-
Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes
-
DOI 10.1038/sj.embor.7400704, PII 7400704
-
Hébert S. S., Serneels L., Tolia A., Craessaerts K., Derks C., Filippov M. A., Mller U., De Strooper B., Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes EMBO Reports 2006 7 7 739 745 (Pubitemid 43986273)
-
(2006)
EMBO Reports
, vol.7
, Issue.7
, pp. 739-745
-
-
Hebert, S.S.1
Serneels, L.2
Tolia, A.3
Craessaerts, K.4
Derks, C.5
Filippov, M.A.6
Muller, U.7
De Strooper, B.8
-
124
-
-
47549083667
-
Increased AICD generation does not result in increased nuclear translocation or activation of target gene transcription
-
Waldron E., Isbert S., Kern A., Jaeger S., Martin A. M., Hébert S. S., Behl C., Weggen S., De Strooper B., Pietrzik C. U., Increased AICD generation does not result in increased nuclear translocation or activation of target gene transcription Experimental Cell Research 2008 314 13 2419 2433
-
(2008)
Experimental Cell Research
, vol.314
, Issue.13
, pp. 2419-2433
-
-
Waldron, E.1
Isbert, S.2
Kern, A.3
Jaeger, S.4
Martin, A.M.5
Hébert, S.S.6
Behl, C.7
Weggen, S.8
De Strooper, B.9
Pietrzik, C.U.10
-
125
-
-
58049089518
-
Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: Implications for Alzheimer disease
-
Belyaev N. D., Nalivaeva N. N., Makova N. Z., Turner A. J., Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease EMBO Reports 2009 10 1 94 100
-
(2009)
EMBO Reports
, vol.10
, Issue.1
, pp. 94-100
-
-
Belyaev, N.D.1
Nalivaeva, N.N.2
Makova, N.Z.3
Turner, A.J.4
-
126
-
-
78650669822
-
The transcriptionally active amyloid precursor protein (APP) intracellular domain is preferentially produced from the 695 isoform of APP in a -secretase-dependent pathway
-
Belyaev N. D., Kellett K. A. B., Beckett C., Makova N. Z., Revett T. J., Nalivaeva N. N., Hooper N. M., Turner A. J., The transcriptionally active amyloid precursor protein (APP) intracellular domain is preferentially produced from the 695 isoform of APP in a -secretase-dependent pathway The Journal of Biological Chemistry 2010 285 53 41443 41454
-
(2010)
The Journal of Biological Chemistry
, vol.285
, Issue.53
, pp. 41443-41454
-
-
Belyaev, N.D.1
Kellett, K.A.B.2
Beckett, C.3
Makova, N.Z.4
Revett, T.J.5
Nalivaeva, N.N.6
Hooper, N.M.7
Turner, A.J.8
-
127
-
-
82555195160
-
-secretase-mediated regulation of neprilysin: Influence of cell density and aging and modulation by Imatinib
-
Bauer C., Pardossi-Piquard R., Dunys J., -secretase-mediated regulation of neprilysin: influence of cell density and aging and modulation by Imatinib Journal of Alzheimer's Disease 2011 27 3 511 520
-
(2011)
Journal of Alzheimer's Disease
, vol.27
, Issue.3
, pp. 511-520
-
-
Bauer, C.1
Pardossi-Piquard, R.2
Dunys, J.3
-
128
-
-
83955164283
-
The impact of amyloid precursor protein signalling and histone deacetylase inhibition on neprilysin expression in human prostate cells
-
Hong Y., Beckett C., Belyaev N. D., Turner A. J., The impact of amyloid precursor protein signalling and histone deacetylase inhibition on neprilysin expression in human prostate cells International Journal of Cancer 2012 130 4 775 786
-
(2012)
International Journal of Cancer
, vol.130
, Issue.4
, pp. 775-786
-
-
Hong, Y.1
Beckett, C.2
Belyaev, N.D.3
Turner, A.J.4
-
129
-
-
70350370474
-
Nuclear signaling by the APP intracellular domain occurs predominantly through the amyloidogenic processing pathway
-
Goodger Z. V., Rajendran L., Trutzel A., Kohli B. M., Nitsch R. M., Konietzko U., Nuclear signaling by the APP intracellular domain occurs predominantly through the amyloidogenic processing pathway Journal of Cell Science 2009 122 20 3703 3714
-
(2009)
Journal of Cell Science
, vol.122
, Issue.20
, pp. 3703-3714
-
-
Goodger, Z.V.1
Rajendran, L.2
Trutzel, A.3
Kohli, B.M.4
Nitsch, R.M.5
Konietzko, U.6
-
130
-
-
79953119109
-
Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex
-
article 160
-
Aydin D., Filippov M. A., Tschpe J. A., Gretz N., Prinz M., Eils R., Brors B., Mller U. C., Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex BMC Genomics 2011 12, article 160
-
(2011)
BMC Genomics
, vol.12
-
-
Aydin, D.1
Filippov, M.A.2
Tschpe, J.A.3
Gretz, N.4
Prinz, M.5
Eils, R.6
Brors, B.7
Mller, U.C.8
-
131
-
-
84655166492
-
The physiology of the -amyloid precursor protein Intracellular domain AICD
-
Pardossi-Piquard R., Checler F., The physiology of the -amyloid precursor protein Intracellular domain AICD Journal of Neurochemistry 2012 120 supplement 1 109 124
-
(2012)
Journal of Neurochemistry
, vol.120
, Issue.SUPPL. 1
, pp. 109-124
-
-
Pardossi-Piquard, R.1
Checler, F.2
-
132
-
-
79952263667
-
Mediator is a transducer of amyloid-precursor-protein-dependent nuclear signalling
-
Xu X., Zhou H., Boyer T. G., Mediator is a transducer of amyloid-precursor-protein-dependent nuclear signalling EMBO Reports 2011 12 3 216 222
-
(2011)
EMBO Reports
, vol.12
, Issue.3
, pp. 216-222
-
-
Xu, X.1
Zhou, H.2
Boyer, T.G.3
-
133
-
-
79952274223
-
Mediator: The missing link in amyloid precursor protein nuclear signalling
-
Turner A. J., Belyaev N. D., Nalivaeva N. N., Mediator: the missing link in amyloid precursor protein nuclear signalling EMBO Reports 2011 12 3 180 181
-
(2011)
EMBO Reports
, vol.12
, Issue.3
, pp. 180-181
-
-
Turner, A.J.1
Belyaev, N.D.2
Nalivaeva, N.N.3
-
134
-
-
58149314221
-
Valproic acid inhibits A production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models
-
Qing H., He G., Ly P. T. T., Fox C. J., Staufenbiel M., Cai F., Zhang Z., Wei S., Sun X., Chen C. H., Zhou W., Wang K., Song W., Valproic acid inhibits A production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models Journal of Experimental Medicine 2008 205 12 2781 2789
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.12
, pp. 2781-2789
-
-
Qing, H.1
He, G.2
Ly, P.T.T.3
Fox, C.J.4
Staufenbiel, M.5
Cai, F.6
Zhang, Z.7
Wei, S.8
Sun, X.9
Chen, C.H.10
Zhou, W.11
Wang, K.12
Song, W.13
-
136
-
-
76749091005
-
Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease
-
Kilgore M., Miller C. A., Fass D. M., Hennig K. M., Haggarty S. J., Sweatt J. D., Rumbaugh G., Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease Neuropsychopharmacology 2010 35 4 870 880
-
(2010)
Neuropsychopharmacology
, vol.35
, Issue.4
, pp. 870-880
-
-
Kilgore, M.1
Miller, C.A.2
Fass, D.M.3
Hennig, K.M.4
Haggarty, S.J.5
Sweatt, J.D.6
Rumbaugh, G.7
-
137
-
-
34548515503
-
Gleevec increases levels of the amyloid precursor protein intracellular domain and of the amyloid-β- degrading enzyme neprilysin
-
DOI 10.1091/mbc.E07-01-0035
-
Eisele Y. S., Baumann M., Klebl B., Nordhammer C., Jucker M., Kilger E., Gleevec increases levels of the amyloid precursor protein intracellular domain and of the amyloid- degrading enzyme neprilysin Molecular Biology of the Cell 2007 18 9 3591 3600 (Pubitemid 47378696)
-
(2007)
Molecular Biology of the Cell
, vol.18
, Issue.9
, pp. 3591-3600
-
-
Eisele, Y.S.1
Baumann, M.2
Klebl, B.3
Nordhammer, C.4
Jucker, M.5
Kilger, E.6
-
138
-
-
65549149865
-
C-Abl modulates AICD dependent cellular responses: Transcriptional induction and apoptosis
-
Vzquez M. C., Vargas L. M., Inestrosa N. C., Alvarez A. R., C-Abl modulates AICD dependent cellular responses: transcriptional induction and apoptosis Journal of Cellular Physiology 2009 220 1 136 143
-
(2009)
Journal of Cellular Physiology
, vol.220
, Issue.1
, pp. 136-143
-
-
Vzquez, M.C.1
Vargas, L.M.2
Inestrosa, N.C.3
Alvarez, A.R.4
-
139
-
-
0034075990
-
Methylation of the neutral endopeptidase gene promoter in human prostate cancers
-
Usmani B. A., Shen R., Janeczko M., Papandreou C. N., Lee W. H., Nelson W. G., Nelson J. B., Nanus D. M., Methylation of the neutral endopeptidase gene promoter in human prostate cancers Clinical Cancer Research 2000 6 5 1664 1670 (Pubitemid 30305058)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.5
, pp. 1664-1670
-
-
Usmani, B.A.1
Shen, R.2
Janeczko, M.3
Papandreou, C.N.4
Lee, W.-H.5
Nelson, W.G.6
Nelson, J.B.7
Nanus, D.M.8
-
140
-
-
0034901533
-
Tumor-suppressive effects of neutral endopeptidase in androgen-independent prostate cancer cells
-
Dai J., Shen R., Sumitomo M., Goldberg J. S., Geng Y., Navarro D., Xu S., Koutcher J. A., Garzotto M., Powell C. T., Nanus D. M., Tumor-suppressive effects of neutral endopeptidase in androgen-independent prostate cancer cells Clinical Cancer Research 2001 7 5 1370 1377 (Pubitemid 32708694)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.5
, pp. 1370-1377
-
-
Dai, J.1
Shen, R.2
Sumitomo, M.3
Goldberg, J.S.4
Geng, Y.5
Navarro, D.6
Xu, S.7
Koutcher, J.A.8
Garzotto, M.9
Powell, C.T.10
Nanus, D.M.11
-
141
-
-
21844431659
-
Etiology of sporadic Alzheimer's disease: Somatostatin, neprilysin, and amyloid β peptide
-
DOI 10.1016/j.mehy.2005.02.045, PII S0306987705001775
-
Hama E., Saido T. C., Etiology of sporadic Alzheimer's disease: somatostatin, neprilysin, and amyloid peptide Medical Hypotheses 2005 65 3 498 500 (Pubitemid 40956947)
-
(2005)
Medical Hypotheses
, vol.65
, Issue.3
, pp. 498-500
-
-
Hama, E.1
Saido, T.C.2
|