Somatostatinergic systems in brain: Networks and functions

Molecular and Cellular Endocrinology

Volumn 286, Issue 1-2, 2008, Pages 75-87

  Viollet, Cécile ^a,b   Lepousez, Gabriel ^a,b   Loudes, Catherine ^a,b   Videau, Catherine ^a,b   Simon, Axelle ^a,b   Epelbaum, Jacques ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Central nervous system; Interneurons; Receptors; Somatostatin; Sst

Indexed keywords

G PROTEIN COUPLED RECEPTOR; SOMATOSTATIN;

ALZHEIMER DISEASE; ARTICLE; BRAIN REGION; CELLULAR DISTRIBUTION; CENTRAL NERVOUS SYSTEM; COGNITION; EPILEPSY; HUMAN; MOTOR ACTIVITY; NERVE CELL NETWORK; NERVE FUNCTION; NEUROANATOMY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SENSORY SYSTEM; SLEEP PATTERN;

EID: 43549112903     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2007.09.007     Document Type: Article

References (117)

1. D. Aguado-Llera E. Arilla-Ferreiro A. Campos-Barros L. Puebla-Jimenez V. Barrios Protective effects of insulin-like growth factor-I on the somatostatinergic system in the temporal cortex of beta-amyloid-treated rats J. Neurochem. 92 3 2005 607 615
2. D. Aguado-Llera E. Arilla-Ferreiro J.A. Chowen J. Argente L. Puebla-Jimenez L.M. Frago V. Barrios 17beta-Estradiol protects depletion of rat temporal cortex somatostatinergic system by beta-amyloid Neurobiol. Aging 28 2007 1396 1409
3. J.P. Allen G.J. Hathway N.J. Clarke M.I. Jowett S. Topps K.M. Kendrick P.P. Humphrey L.S. Wilkinson P.C. Emson Somatostatin receptor 2 knockout/lacZ knockin mice show impaired motor coordination and reveal sites of somatostatin action within the striatum Eur. J. Neurosci. 17 2003 1881 1895
4. S. Araneda K. Gysling A. Calas Raphe serotonergic neurons projecting to the olfactory bulb contain galanin or somatostatin but not neurotensin Brain Res. Bull. 49 1999 209 214
5. S.C. Baraban M.K. Tallent Interneuron diversity series: interneuronal neuropeptides—endogenous regulators of neuronal excitability Trends Neurosci. 27 2004 135 142
6. M.H. Bassant A. Simon F. Poindessous-Jazat Z. Csaba J. Epelbaum P. Dournaud Medial septal GABAergic neurons express the somatostatin sst2A receptor: functional consequences on unit firing and hippocampal theta J. Neurosci. 25 2005 2032 2041
7. N.F. Berbari G.A. Bishop C.C. Askwith J.S. Lewis K. Mykytyn Hippocampal neurons possess primary cilia in culture J. Neurosci. Res. 85 2007 1095 1100
8. V. Bernard M. Decossas I. Liste B. Bloch Intraneuronal trafficking of G-protein-coupled receptors in vivo Trends Neurosci. 29 2006 140 147
9. K. Bouyer C. Loudes I.C. Robinson J. Epelbaum A. Faivre-Bauman Sexually dimorphic distribution of sst2A somatostatin receptors on growth hormone-releasing hormone neurons in mice Endocrinology 147 2006 2670 2674
10. P. Brazeau W. Vale R. Burgus N. Ling M. Butcher J. Rivier R. Guillemin Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone Science 179 1973 77 79
11. P.S. Buckmaster V. Otero-Corchon M. Rubinstein M.J. Low Heightened seizure severity in somatostatin knockout mice Epilepsy Res. 48 2002 43 56
12. M. Cammalleri D. Cervia D. Langenegger Y. Liu M.D. Monte D. Hoyer P. Bagnoli Somatostatin receptors differentially affect spontaneous epileptiform activity in mouse hippocampal slices Eur. J. Neurosci. 20 2004 2711 2721
13. M. Cammalleri D. Cervia M. Dal Monte D. Martini D. Langenegger D. Fehlmann D. Feuerbach B. Pavan D. Hoyer P. Bagnoli Compensatory changes in the hippocampus of somatostatin knockout mice: upregulation of somatostatin receptor 2 and its function in the control of bursting activity and synaptic transmission Eur. J. Neurosci. 23 2006 2402 2404
14. B. Cauli X.K. Tong A. Rancillac N. Serluca B. Lambolez J. Rossier E. Hamel Cortical GABA interneurons in neurovascular coupling: relays for subcortical vasoactive pathways J. Neurosci. 24 2004 8940 8949
15. D. Cervia G. Casini P. Bagnoli Physiology and pathology of somatostatin in the mammalian retina: a current view Mol. Cell. Endocrinol 286 2008 112 122
16. Y.S. Choi S.L. Lin B. Lee P. Kurup H.Y. Cho J.R. Naegele P.J. Lombroso K. Obrietan Status epilepticus-induced somatostatinergic hilar interneuron degeneration is regulated by striatal enriched protein tyrosine phosphatase J. Neurosci. 27 2007 2999 3009
17. J.A. Chowen L.M. Frago J. Argente The regulation of GH secretion by sex steroids Eur. J. Endocrinol. 151 Suppl. 3 2004 U95 U100
18. Z. Csaba P. Dournaud Cellular biology of somatostatin receptors Neuropeptides 35 2001 1 23
19. Z. Csaba A. Simon L. Helboe J. Epelbaum P. Dournaud Neurochemical characterization of receptor-expressing cell populations by in vivo agonist-induced internalization: insights from the somatostatin sst2A receptor J. Comp. Neurol. 454 2002 192 199
20. Z. Csaba B. Lelouvier C. Viollet V. El Ghouzzi K. Toyama C. Videau V. Bernard P. Dournaud Activated somatostatin type 2 receptors traffic in vivo in central neurons from dendrites to the trans Golgi before recycling Traffic 8 2007 820 834
21. N.C. De Lanerolle J.H. Kim R.J. Robbins D.D. Spencer Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy Brain Res. 495 1989 387 395
22. L. de Lecea Cortistatin-functions in the Central Nervous System Mol. Cell. Endocrinol. 286 2008 88 95
23. P. Dournaud P. Delaere J.J. Hauw J. Epelbaum Differential correlation between neurochemical deficits, neuropathology, and cognitive status in Alzheimer's disease Neurobiol. Aging 16 1995 817 823
24. P. Dournaud H. Boudin A. Schonbrunn G.S. Tannenbaum A. Beaudet Interrelationships between somatostatin sst2A receptors and somatostatin-containing axons in rat brain: evidence for regulation of cell surface receptors by endogenous somatostatin J. Neurosci. 18 1998 1056 1071
25. P. Dournaud A. Slama A. Beaudet J. Epelbaum Somatostatin receptors R. Quirion A. Björklund T. Hökfelt Peptide Receptors (Handbook of Chemical Neuroanatomy) vol. 16 2000 Elsevier Boston, MA 1 43 (Part 1)
26. P. Dutar C. Vaillend C. Viollet J.M. Billard B. Potier A.S. Carlo A. Ungerer J. Epelbaum Spatial learning and synaptic hippocampal plasticity in type 2 somatostatin receptor knock-out mice Neuroscience 112 2002 455 466
27. M. Engström J.M. Savola S. Wurster Differential efficacies of somatostatin receptor agonists for G-protein activation and desensitization of somatostatin receptor subtype 4-mediated responses J. Pharmacol. Exp. Ther. 316 2006 1262 1268
28. J. Epelbaum Somatostatin in the central nervous system: physiology and pathological modifications Prog. Neurobiol. 27 1986 63 100
29. J. Epelbaum P. Dournaud M. Fodor C. Viollet The neurobiology of somatostatin Crit. Rev. Neurobiol. 8 1994 25 44
30. T. Florio Somatostatin/somatostatin receptor signalling: phosphotyrosine phosphatases Mol. Cell. Endocrinol. 286 2008 40 48
31. M. Fodor C. Kordon J. Epelbaum Anatomy of the hypophysiotropic somatostatinergic and growth hormone-releasing hormone system, minireview Neurochem. Res. 31 2006 137 143
32. M.A. Frye P.J. Pazzaglia M.S. George D.A. Luckenbaugh E. Vanderham C.L. Davis D.R. Rubinow R.M. Post Low CSF somatostatin associated with response to nimodipine in patents with affective illness Biol. Psychiatry 53 2003 180 183
33. E. Galarraga C. Vilchis T. Tkatch H. Salgado F. Tecuapetla T. Perez-Rosello E. Perez-Garci E. Hernandez-Echeagaray D.J. Surmeier J. Bargas Somatostatinergic modulation of firing pattern and calcium-activated potassium currents in medium spiny neostriatal neurons Neuroscience 146 2007 537 554
34. K. Giehl P. Mestres Somatostatin-mRNA expression in brainstem projections into the medial preoptic nucleus Exp. Brain Res. 1033 1995 344 354
35. C. Glorioso M. Sabatini T. Unger T. Hashimoto L.M. Monteggia D.A. Lewis K. Mirnics Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood Mol. Psychiatry 11 2006 633 648
36. E. Gonzalez-Rey N. Varela A.F. Sheibanie A. Chorny D. Ganea M. Delgado Cortistatin, an antiinflammatory peptide with therapeutic action in inflammatory bowel disease Proc. Natl. Acad. Sci. U.S.A. 103 2006 4228 4233
37. M. Grilli L. Raiteri A. Pittaluga Somatostatin inhibits glutamate release from mouse cerebrocortical nerve endings through presynaptic sst2 receptors linked to the adenylyl cyclase-protein kinase A pathway Neuropharmacology 46 2004 388 396
38. G. Grosse S. Djalali D.R. Deng M. Holtje B. Hinz K. Schwartzkopff M. Cygon T. Rothe T. Stroh R. Hellweg G. Ahnert-Hilger H. Hortnag Area-specific effects of brain-derived neurotrophic factor (BDNF) genetic ablation on various neuronal subtypes of the mouse brain Brain Res. Dev. Brain Res. 156 2005 111 126
39. D. Grouselle R. Winsky-Sommerer J.P. David A. Delacourte P. Dournaud J. Epelbaum Loss of somatostatin-like immunoreactivity in the frontal cortex of Alzheimer patients carrying the apolipoprotein epsilon 4 allele Neurosci. Lett. 255 1998 21 24
40. A.I. Gulyas N. Hajos I. Katona T.F. Freund Interneurons are the local targets of hippocampal inhibitory cells which project to the medial septum Eur. J. Neurosci. 17 2003 1861 1872
41. M. Gutierrez-Mecinas C. Crespo J.M. Blasco-Ibanez F.J. Gracia-Llanes A.I. Marques-Mari F.J. Martinez-Guijarro Characterization of somatostatin- and cholecystokinin-immunoreactive periglomerular cells in the rat olfactory bulb J. Comp. Neurol. 4894 2005 467 479
42. B. Halabisky F. Shen J.R. Huguenard D.A. Prince Electrophysiological classification of somatostatin-positive interneurons in mouse sensorimotor cortex J. Neurophysiol. 96 2006 834 845
43. J.P. Hannon C. Bruns G. Wesbecker D. Hoyer Somatostatin receptor gene family-subtype selectivity for ligand binding C.B. Srikant Somatostatin 2004 Kluwers Academic Publishers Norwell, MA 81 106
44. N. Jiang H. Furue T. Katafuchi M. Yoshimura Somatostatin directly inhibits substantia gelatinosa neurons in adult rat spinal dorsal horn in vitro Neurosci. Res. 47 2003 97 107
45. S. Jinno T. Kosaka Patterns of colocalization of neuronal nitric oxide synthase and somatostatin-like immunoreactivity in the mouse hippocampus: quantitative analysis with optical dissector Neuroscience 124 2004 797 808
46. S. Jinno T. Kosaka Cellular architecture of the mouse hippocampus: a quantitative aspect of chemically defined GABAergic neurons with stereology Neurosci. Res. 56 2006 229 245
47. C. Kapfer L.L. Glickfeld B.V. Atallah M. Scanziani Supralinear increase of recurrent inhibition during sparse activity in the somatosensory cortex Nat. Neurosci. 10 2007 743 753
48. I. Katona L. Acsau Dy T.F. Freund Postsynaptic targets of somatostatin-immunoreactive interneurons in the rat hippocampus Neuroscience 88 1999 37 55
49. Y. Kawaguchi Y. Kubota Neurochemical features and synaptic connections of large physiologically-identified GABAergic cells in the rat frontal cortex Neuroscience 85 1998 677 701
50. C. Kohler L.G. Eriksson S. Davies V. Chan-Palay Co-localization of neuropeptide tyrosine and somatostatin immunoreactivity in neurons of individual subfields of the rat hippocampal region Neurosci. Lett. 78 1987 1 6
51. H.J. Kreienkamp E. Akgun H. Baumeister W. Meyerhof D. Richter Somatostatin receptor subtype 1 modulates basal inhibition of growth hormone release in somatotrophs FEBS Lett. 462 1999 464 466
52. S. Kuwahara D. Kesuma Sari Y. Tsukamoto S. Tanaka F. Sasaki Age-related changes in growth hormone (GH)-releasing hormone and somatostatin neurons in the hypothalamus and in GH cells in the anterior pituitary of female mice Brain Res. 1025 2004 113 122
53. H. Lahlou J. Guillermet M. Hortala F. Vernejoul S. Pyronnet C. Bousquet C. Susini Molecular signaling of somatostatin receptors Ann. N.Y. Acad. Sci. 1014 2004 21 31
54. C. Lanneau M.T. Bluet-Pajot P. Zizzari Z. Csaba P. Dournaud L. Helboe D. Hoyer E. Pellegrini G.S. Tannenbaum J. Epelbaum R. Gardette Involvement of the Sst1 somatostatin receptor subtype in the intrahypothalamic neuronal network regulating growth hormone secretion: an in vitro and in vivo antisense study Endocrinology 141 2000 967 979
55. C. Lanneau S. Peineau F. Petit J. Epelbaum R. Gardette Somatostatin modulation of excitatory synaptic transmission between periventricular and arcuate hypothalamic nuclei in vitro J. Neurophysiol. 84 2000 1464 1474
56. P.J. Larsen V. Seier A. Fink-Jensen J.J. Holst J. Warberg N. Vrang Cocaine- and amphetamine-regulated transcript is present in hypothalamic neuroendocrine neurones and is released to the hypothalamic-pituitary portal circuit J. Neuroendocrinol. 15 2003 219 226
57. A. Leake I.N. Ferrier Alterations in neuropeptides in aging and disease. Pathophysiology and potential for clinical intervention Drugs Aging 3 1993 408 427
58. C. Leranth A.J. Malcolm M. Frotscher Afferent and efferent synaptic connections of somatostatin-immunoreactive neurons in the rat fascia dentata J. Comp. Neurol. 2951 1990 111 122
59. N. Leresche E. Asprodini Z. Emri D.W. Cope V. Crunelli Somatostatin inhibits GABAergic transmission in the sensory thalamus via presynaptic receptors Neuroscience 98 2000 513 522
60. P. Leroux C. Bodenant E. Bologna B. Gonzalez H. Vaudry Transient expression of somatostatin receptors in the brain during development Ciba Found. Symp. 190: Somatostatin and its Receptors 1995 John Wiley & Sons Ltd. Chichester 127 141
61. M. Ludwig G. Leng Dendritic peptide release and peptide-dependent behaviours Nat. Rev. Neurosci. 7 2006 126 136
62. Y. Ma H. Hu A.S. Berrebi P.H. Mathers A. Agmon Distinct subtypes of somatostatin-containing neocortical interneurons revealed in transgenic mice J. Neurosci. 2619 2006 5069 5082
63. G. Maccaferri J.D.B. Roberts P. Szucs C.A. Cottingham P. Somogyi Cell surface domain specific postsynaptic currents evoked by identified GABAergic in vitro neurones in rat hippocampus J. Physiol. 524 2000 91 116
64. J.C. Maiza D. Vezzosi M. Matta F. Donadille F. Loubes-Lacroix M. Cournot A. Bennet P. Caron Long-term (up to 18 years) effects on GH/IGF-1 hypersecretion and tumour size of primary somatostatin analogue (SSTa) therapy in patients with GH-secreting pituitary adenoma responsive to SSTa Clin. Endocrinol. 67 2007 282 289
65. M. Malcangio GDNF and somatostatin in sensory neurones Curr. Opin. Pharmacol. 2003 341 345
66. P.W. Mantyh S.P. Hunt Neuropeptides are present in projection neurones at all levels in visceral and taste pathways: from periphery to sensory cortex Brain Res. 299 1984 297 312
67. H. Markram M. Toledo-Rodriguez Y. Wang A. Gupta G. Silberberg C. Wu Interneurons of the neocortical inhibitory system Nat. Rev. Neurosci. 5 2004 793 807
68. W.F. Marshall S. Nonaka Cilia: tuning in to the cell's antenna Curr. Biol. 16 2006 604 614
69. S. Meis L. Sosulina S. Schulz V. Hollt H.C. Pape Mechanisms of somatostatin-evoked responses in neurons of the rat lateral amygdala Eur. J. Neurosci. 21 2005 755 762
70. T. Momiyama L. Zaborszky Somatostatin presynaptically inhibits both GABA and glutamate release onto rat basal forebrain cholinergic neurons J. Neurophysiol. 96 2006 686 694
71. D. Moneta C. Richichi M. Aliprandi P. Dournaud P. Dutar J.M. Billard A.S. Carlo C. Viollet J.P. Hannon D. Fehlmann C. Nunn D. Hoyer J. Epelbaum A. Vezzani Somatostatin receptor subtypes 2 and 4 affect seizure susceptibility and hippocampal excitatory neurotransmission in mice Eur. J. Neurosci. 16 2002 843 849
72. J.F. Muller F. Mascagni A.J. Mcdonald Postsynaptic targets of somatostatin-containing interneurons in the rat basolateral amygdala J. Comp. Neurol. 500 2007 513 529
73. A. Nakata H. Saito N. Nishiyama Facilitatory role of somatostatin via muscarinic cholinergic system in the generation of long-term potentiation in the rat dentate gyrus in vivo Brain Res. 723 1996 135 140
74. N. Nakatani E. Hattori T. Ohnishi B. Dean Y. Iwayama I. Matsumoto T. Kato N. Osumi T. Higuchi S. Niwa T. Yoshikawa Genome-wide expression analysis detects eight genes with robust alterations specific to bipolar I disorder: relevance to neuronal network perturbation Hum. Mol. Genet. 15 2006 1949 1962
75. H. Nawa M.A. Pelleymounter J. Carnahan Intraventricular administration of BDNF increases neuropeptide expression in newborn rat brain J. Neurosci. 14 6 1994 3751 3765
76. G. Olias C. Viollet H. Kusserow J. Epelbaum W. Meyerhof Regulation and function of somatostatin receptors J. Neurochem. 89 2004 1057 1091
77. A.A. Oliva Jr. M. Jiang T. Lam K.L. Smith J.W. Swann Novel hippocampal interneuronal subtypes identified using transgenic mice that express Green Fluorescent Protein in GABAergic interneurons J. Neurosci. 209 2000 3354 3368
78. S. Peineau B. Potier F. Petit P. Dournaud J. Epelbaum R. Gardette AMPA-sst2 somatostatin receptor interaction in rat hypothalamus requires activation of NMDA and/or metabotropic glutamate receptors and depends on intracellular calcium J. Physiol. 546 2003 101 117
79. A.R. Pierotti A.J. Harmar J. Simpson C.M. Yates High-molecular-weight forms of somatostatin are reduced in Alzheimer's disease and Down's syndrome Neurosci. Lett. 63 1986 141 146
80. E. Pinter Z. Helyes J. Szolcsanyi Inhibitory effect of somatostatin on inflammation and nociception Pharmacol. Ther. 112 2006 440 456
81. R.J. Robbins M.L. Brines J.H. Kim T. Adrian N. de Lanerolle S. Welsh D.D. Spencer A selective loss of somatostatin in the hippocampus of patients with temporal lobe epilepsy Ann. Neurol. 29 1991 325 332
82. S. Saha Z. Henderson T.F.C. Batten Somatostatin immunoreactivity in axon terminals in rat nucleus tractus solitarii arising from central nucleus of amygdala: coexistence with GABA and postsynaptic expression of sst2A receptor J. Chem. Neuroanat. 24 2002 1 13
83. T. Saito N. Iwata S. Tsubuki Y. Takaki J. Takano S.M. Huang T. Suemoto M. Higuchi T.C. Saido Somatostatin regulates brain amyloid beta peptide Abeta(42) through modulation of proteolytic degradation Nat. Med. 11 2005 434 439
84. P. Sarret J.M. Botto J.P. Vincent J. Mazella A. Beaudet Preferential expression of sst2A over sst2B somatostatin receptor splice variant in rat brain and pituitary Neuroendocrinology 68 1998 37 43
85. M. Schindler P.P. Humphrey S. Lohrke E. Friauf Immunohistochemical localization of the somatostatin sst2(b) receptor splice variant in the rat central nervous system Neuroscience 90 1999 859 874
86. M. Schreff S. Schulz M. Handel G. Keilhoff H. Braun G. Pereira M. Klutzny H. Schmidt G. Wolf V. Hollt Distribution, targeting, and internalization of the sst4 somatostatin receptor in rat brain J. Neurosci. 20 2000 3785 3797
87. S. Schulz M. Handel M. Schreff H. Schmidt V. Hollt Localization of five somatostatin receptors in the rat central nervous system using subtype-specific antibodies J. Physiol. Paris 94 2000 259 264
88. S. Shiosaka Ontogeny of the central somatostatinergic system A. Björklund T. Hökfelt M. Tohyama Handbooks of Chemical Neuroanatomy vol. 10 1992 Elsevier Amsterdam 369 398
89. P. Song J.Y. Hu Z.Q. Zhao Spinal somatostatin SSTR2A receptors are preferentially up-regulated and involved in thermonociception but not mechanonociception Exp. Neurol. 178 2002 280 287
90. L. Sosulina L.S. Meis G. Seifert C. Steinhauser H.-C. Pape Classification of projection neurons and interneurons in the rat lateral amygdala based upon cluster analysis Mol. Cell. Neurosci. 33 2006 57 67
91. A.D. Spier L. de Lecea Cortistatin: a member of the somatostatin neuropeptide family with distinct physiological functions Brain Res. Brain Res. Rev. 33 2000 228 241
92. T. Stroh H.J. Kreienkamp A. Beaudet Immunohistochemical distribution of the somatostatin receptor subtype 5 in the adult rat brain: predominant expression in the basal forebrain J. Comp. Neurol. 412 1999 69 82
93. T. Stroh P. Sarret G.S. Tannenbaum A. Beaudet Immunohistochemical distribution and subcellular localization of the somatostatin receptor subtype 1 (sst1) in the rat hypothalamus Neurochem. Res. 31 2006 247 257
94. M.Z. Strowski M. Kohler H.Y. Chen M.E. Trumbauer Z. Li D. Szalkowski S. Gopal-Truter J.K. Fisher J.M. Schaeffer A.D. Blake B.B. Zhang H.A. Wilkinson Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis Mol. Endocrinol. 17 2003 93 106
95. R.K. Stumm C. Zhou S. Schulz M. Endres G. Kronenberg J.P. Allen G. Tulipano V. Hollt Somatostatin receptor 2 is activated in cortical neurons and contributes to neurodegeneration after focal ischemia J. Neurosci. 24 2004 11404 11415
96. Q.Q. Sun S.C. Baraban D.A. Prince J.R. Huguenard Target-specific neuropeptide Y-ergic synaptic inhibition and its network consequences within the mammalian thalamus J. Neurosci. 23 2003 9639 9649
97. J.M. Tepper J.P. Bolam Functional diversity and specificity of neostriatal interneurons Curr. Opin. Neurobiol. 14 2004 685 692
98. K. Thermos P. Bagnoli J. Epelbaum D. Hoyer The somatostatin sst1 receptor: an autoreceptor for somatostatin in brain and retina? Pharmacol. Ther. 110 2006 455 464
99. M. Toledo-Rodriguez P. Goodman M. Illic C. Wu H. Markram Neuropeptide and calcium-binding protein gene expression profiles predict neuronal anatomical type in the juvenile rat J. Physiol. 567 2005 401 413
100. R. Tomioka K. Okamoto T. Furuta F. Fujiyama T. Iwasato Y. Yanagawa K. Obata T. Kaneko N. Tamamaki Demonstration of long-range GABAergic connections distributed throughout the mouse neocortex Eur. J. Neurosci. 21 2005 1587 1600
101. A. Vezzani D. Hoyer Brain somatostatin: a candidate inhibitory role in seizures and epileptogenesis Eur. J. Neurosci. 11 1999 3767 3776
102. F. Viana B. Hille Modulation of high voltage-activated calcium channels by somatostatin in acutely isolated rat amygdaloid neurons J. Neurosci. 16 1996 6000 6011
103. C. Videau U. Hochgeschwender H.J. Kreienkamp M.B. Brennan C. Viollet D. Richter J. Epelbaum Characterisation of [I-125]-Tyr(0)DTrp(8)-somatostatin binding in sst1-to sst4-and SRIF-gene-invalidated mouse brain Naunyn Schmiedebergs Arch. Pharmacol. 367 2003 562 571
104. C. Viollet C. Bodenant C. Prunotto D. Roosterman J. Schaefer W. Meyerhof J. Epelbaum H. Vaudry P. Leroux Differential expression of multiple somatostatin receptors in the rat cerebellum during development J. Neurochem. 68 1997 2263 2272
105. C. Viollet C. Vaillend C. Videau M.T. Bluet-Pajot A. Ungerer A. L’Heritier C. Kopp B. Potier J. Billard J. Schaeffer R.G. Smith S.P. Rohrer H. Wilkinson H. Zheng J. Epelbaum Involvement of sst2 somatostatin receptor in locomotor, exploratory activity and emotional reactivity in mice Eur. J. Neurosci. 12 2000 3761 3770
106. C. Viollet C. Videau J. Epelbaum Somatostatin and behaviour: the need for genetically engineered models J. Physiol. Paris 94 2000 179 183
107. Y. Wang M. Toledo-Rodriguez A. Gupta C. Wu G. Silberberg J. Luo H. Markram Anatomical, physiological and molecular properties of Martinotti cells in the somatosensory cortex of the juvenile rat J. Physiol. 561 2004 65 90
108. R. Widmann N. Mensdorff-Pouilly K. Pfaller G. Sperk Evidence for somatostatin-containing fibers projecting from the pallidal complex to the striatum of the rat J. Neurochem. 48 1987 1857 1861
109. R. Winsky-Sommerer D. Grouselle C. Rougeot V. Laurent J.P. David A. Delacourte P. Dournaud N.G. Seidah I. Lindberg S. Trottier J. Epelbaum The proprotein convertase PC2 is involved in the maturation of prosomatostatin to somatostatin-14 but not in the somatostatin deficit in Alzheimer's disease Neuroscience 122 2003 437 447
110. C.P. Wonders S.A. Anderson The origin and specification of cortical interneurons Nat. Rev. Neurosci. 7 2006 687 696
111. E. Yacubova H. Komuro Stage-specific control of neuronal migration by somatostatin Nature 415 2002 77 81
112. L. Zaborszky A. Duque Local synaptic connections of basal forebrain neurons Behav. Brain Res. 115 2000 143 158
113. C.A. Zappone R.S. Sloviter Commissurally projecting inhibitory interneurons of the rat hippocampal dentate gyrus: a colocalization study of neuronal markers and the Retrograde tracer Fluoro-Gold J. Comp. Neurol. 441 2001 324 344
114. T. Zeyda U. Hochgeschwender Null mutant mouse models of somatostatin and cortistatin, and their receptors Mol. Cell. Endocrinol. 286 2008 18 25
115. T. Zeyda N. Diehl R. Paylor M.B. Brennan U. Hochgeschwender Impairment in motor learning of somatostatin null mutant mice Brain Res. 906 2001 107 114
116. W.H. Zhang A. Beaudet G.S. Tannenbaum Sexually dimorphic expression of sst1 and sst2 somatostatin receptor subtypes in the arcuate nucleus and anterior pituitary of adult rats J. Neuroendocrinol. 11 1999 129 136
117. H. Zheng A. Bailey M.H. Jiang K. Honda H.Y. Chen M.E. Trumbauer L.H. Van der Ploeg J.M. Schaeffer G. Leng R.G. Smith Somatostatin receptor subtype 2 knockout mice are refractory to growth hormone-negative feedback on arcuate neurons Mol. Endocrinol. 11 1997 1709 1717