A novel system for in vivo neprilysin gene delivery using a syringe electrode

Journal of Neuroscience Methods

Volumn 193, Issue 2, 2010, Pages 226-231

  Li, Yuanli ^a   Wang, Jue ^a   Liu, Jiankang ^a   Liu, Feng ^b  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Alzheimer disease; Brain tissue; Electroporation; Gene therapy; Neprilysin; Skeletal muscle; Syringe electrode; Tissue damage

Indexed keywords

AMYLOID BETA PROTEIN; MEMBRANE METALLOENDOPEPTIDASE; PLASMID DNA; POLYPEPTIDE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRIC FIELD; ELECTRODE; ELECTROPORATION; ELECTROSTIMULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE THERAPY; GENE TRANSFER; HINDLIMB; MOUSE; MUSCLE INJURY; NEEDLE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; TISSUE DISTRIBUTION; WESTERN BLOTTING;

ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; DNA; ELECTRIC STIMULATION; ELECTRODES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EVANS BLUE; GENE THERAPY; GENE TRANSFER TECHNIQUES; HUMANS; MICE; MICE, INBRED STRAINS; MUSCLE, SKELETAL; MUSCULAR DISEASES; NEPRILYSIN; SYRINGES; TIME FACTORS;

EID: 78049382779     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2010.08.029     Document Type: Article

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