메뉴 건너뛰기




Volumn 105, Issue 34, 2008, Pages 12581-12586

Lack of adrenomedullin in the mouse brain results in behavioral changes, anxiety, and lower survival under stress conditions

Author keywords

[No Author keywords available]

Indexed keywords

ADRENOMEDULLIN; CORTICOSTERONE; CORTICOTROPIN; CRE RECOMBINASE; DIAZEPAM; HALOPERIDOL; METHYLPHENIDATE; PROTEIN; TUBULIN; TUBULIN T ALPHA 1 PROMOTER; UNCLASSIFIED DRUG;

EID: 50449086487     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0803174105     Document Type: Article
Times cited : (61)

References (45)
  • 1
    • 0036443430 scopus 로고    scopus 로고
    • Cell and molecular biology of the multifunctional peptide, adrenomedullin
    • Lopez J, Martinez A (2002) Cell and molecular biology of the multifunctional peptide, adrenomedullin. Int Rev Cytol 221:1-92.
    • (2002) Int Rev Cytol , vol.221 , pp. 1-92
    • Lopez, J.1    Martinez, A.2
  • 2
    • 0032574982 scopus 로고    scopus 로고
    • RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
    • McLatchie LM, et al. (1998) RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature 393:333-339.
    • (1998) Nature , vol.393 , pp. 333-339
    • McLatchie, L.M.1
  • 3
    • 0029598770 scopus 로고
    • Adrenomedullin-immunoreactive neurons in the paraventricular and supraoptic nuclei of the rat
    • Ueta Y, et al. (1995) Adrenomedullin-immunoreactive neurons in the paraventricular and supraoptic nuclei of the rat. Neurosci Lett 202:37-40.
    • (1995) Neurosci Lett , vol.202 , pp. 37-40
    • Ueta, Y.1
  • 4
    • 0033989163 scopus 로고    scopus 로고
    • Distribution of adrenomedullin-like immunoreactivity in the rat central nervous system by light and electron microscopy
    • Serrano J, et al (2000) Distribution of adrenomedullin-like immunoreactivity in the rat central nervous system by light and electron microscopy. Brain Res 853:245-268.
    • (2000) Brain Res , vol.853 , pp. 245-268
    • Serrano, J.1
  • 5
    • 0035840302 scopus 로고    scopus 로고
    • Expression of receptor-activity modifying protein (RAMP) mRNAs in the mouse brain
    • Ueda T, Ugawa S, Saishin Y, Shimada S (2001) Expression of receptor-activity modifying protein (RAMP) mRNAs in the mouse brain. Brain Res Mol Brain Res 93:36-45.
    • (2001) Brain Res Mol Brain Res , vol.93 , pp. 36-45
    • Ueda, T.1    Ugawa, S.2    Saishin, Y.3    Shimada, S.4
  • 6
    • 0142102358 scopus 로고    scopus 로고
    • Adrenomedullin receptor binding sites in rat brain and peripheral tissues
    • Juaneda C, Dumont Y, Chabot JG, Fournier A, Quirion R (2003) Adrenomedullin receptor binding sites in rat brain and peripheral tissues. Eur J Pharmacol 474:165-174.
    • (2003) Eur J Pharmacol , vol.474 , pp. 165-174
    • Juaneda, C.1    Dumont, Y.2    Chabot, J.G.3    Fournier, A.4    Quirion, R.5
  • 7
    • 33646811808 scopus 로고    scopus 로고
    • Immunocytochemical localization of adrenomedullin 2/intermedin-like immunoreactivity in human hypothalamus, heart and kidney
    • Takahashi K, et al. (2006) Immunocytochemical localization of adrenomedullin 2/intermedin-like immunoreactivity in human hypothalamus, heart and kidney. Peptides 27:1383-1389.
    • (2006) Peptides , vol.27 , pp. 1383-1389
    • Takahashi, K.1
  • 8
    • 0031832088 scopus 로고    scopus 로고
    • Central mechanisms for the hypertensive effects of preproadrenomedullin-derived peptides in conscious rats
    • Samson WK, Murphy TC, Resch ZT (1998) Central mechanisms for the hypertensive effects of preproadrenomedullin-derived peptides in conscious rats. Am J Physiol 274:R1505-R1509.
    • (1998) Am J Physiol , vol.274
    • Samson, W.K.1    Murphy, T.C.2    Resch, Z.T.3
  • 9
    • 4644371712 scopus 로고    scopus 로고
    • Adrenomedullin in the rostral ventrolateral medulla increases arterial pressure and heart rate: Roles of glutamate and nitric oxide
    • Xu Y, Krukoff TL (2004) Adrenomedullin in the rostral ventrolateral medulla increases arterial pressure and heart rate: roles of glutamate and nitric oxide. Am J Physiol Regul Integr Comp Physiol 287:R729-R734.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.287
    • Xu, Y.1    Krukoff, T.L.2
  • 10
    • 0029939258 scopus 로고    scopus 로고
    • In vitro recordings from area postrema neurons demonstrate responsiveness to adrenomedullin
    • Allen MA, Ferguson AV (1996) In vitro recordings from area postrema neurons demonstrate responsiveness to adrenomedullin. Am J Physiol 270:R920-R925.
    • (1996) Am J Physiol , vol.270
    • Allen, M.A.1    Ferguson, A.V.2
  • 11
    • 0037154960 scopus 로고    scopus 로고
    • Adrenomedullin expression is up-regulated by ischemia-reperfusion in the cerebral cortex of the adult rat
    • Serrano J, et al. (2002) Adrenomedullin expression is up-regulated by ischemia-reperfusion in the cerebral cortex of the adult rat. Neuroscience 109:717-731.
    • (2002) Neuroscience , vol.109 , pp. 717-731
    • Serrano, J.1
  • 12
    • 44649126027 scopus 로고    scopus 로고
    • Adrenomedullin expression is up-regulated by acute hypobaric hypoxia in the cerebral cortex of the adult rat
    • Serrano J, Fernandez AP, Sanchez J, Rodrigo J, Martinez A (2008) Adrenomedullin expression is up-regulated by acute hypobaric hypoxia in the cerebral cortex of the adult rat. Brain Pathol 18:434-442.
    • (2008) Brain Pathol , vol.18 , pp. 434-442
    • Serrano, J.1    Fernandez, A.P.2    Sanchez, J.3    Rodrigo, J.4    Martinez, A.5
  • 13
    • 0035895276 scopus 로고    scopus 로고
    • Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene
    • Caron KM, Smithies O (2001) Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene. Proc Natl Acad Sci USA 98:615-619.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 615-619
    • Caron, K.M.1    Smithies, O.2
  • 14
    • 0035899895 scopus 로고    scopus 로고
    • Vascular abnormalities and elevated blood pressure in mice lacking adrenomedullin gene
    • Shindo T, et al. (2001) Vascular abnormalities and elevated blood pressure in mice lacking adrenomedullin gene. Circulation 104:1964-1971.
    • (2001) Circulation , vol.104 , pp. 1964-1971
    • Shindo, T.1
  • 15
    • 0036140729 scopus 로고    scopus 로고
    • Adrenomedullin, an endogenous peptide, counteracts cardiovascular damage
    • Shimosawa T, et al. (2002) Adrenomedullin, an endogenous peptide, counteracts cardiovascular damage. Circulation 105:106-111.
    • (2002) Circulation , vol.105 , pp. 106-111
    • Shimosawa, T.1
  • 16
    • 33645230587 scopus 로고    scopus 로고
    • Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene
    • Dackor RT, et al. (2006) Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene. Mol Cell Biol 26:2511-2518.
    • (2006) Mol Cell Biol , vol.26 , pp. 2511-2518
    • Dackor, R.T.1
  • 17
    • 33847658304 scopus 로고    scopus 로고
    • Conditional gene targeting in the mouse nervous system: Insights into brain function and diseases
    • Gaveriaux-Ruff C, Kieffer BL (2007) Conditional gene targeting in the mouse nervous system: Insights into brain function and diseases. Pharmacol Ther 113:619-634.
    • (2007) Pharmacol Ther , vol.113 , pp. 619-634
    • Gaveriaux-Ruff, C.1    Kieffer, B.L.2
  • 18
    • 8444237032 scopus 로고    scopus 로고
    • Ablation of TrkA function in the immune system causes B cell abnormalities
    • Coppola V, et al. (2004) Ablation of TrkA function in the immune system causes B cell abnormalities. Development 131:5185-5195.
    • (2004) Development , vol.131 , pp. 5185-5195
    • Coppola, V.1
  • 19
    • 44249113295 scopus 로고    scopus 로고
    • Intracellular proadrenomedullin-derived peptides decorate the microtubules and contribute to cytoskeleton function
    • Sackett DL, et al. (2008) Intracellular proadrenomedullin-derived peptides decorate the microtubules and contribute to cytoskeleton function. Endocrinology 149:2888-2898.
    • (2008) Endocrinology , vol.149 , pp. 2888-2898
    • Sackett, D.L.1
  • 20
    • 33748278913 scopus 로고    scopus 로고
    • A systematic review and economic model of the effectiveness and cost-effectiveness of methylphenidate, dexamfetamine and atomoxetine for the treatment of attention deficit hyperactivity disorder in children and adolescents
    • King S, et al. (2006) A systematic review and economic model of the effectiveness and cost-effectiveness of methylphenidate, dexamfetamine and atomoxetine for the treatment of attention deficit hyperactivity disorder in children and adolescents. Health Technol Assess 10:1-162.
    • (2006) Health Technol Assess , vol.10 , pp. 1-162
    • King, S.1
  • 21
    • 33749175398 scopus 로고    scopus 로고
    • Noncompensation in peptide/receptor gene expression and distinct behavioral phenotypes in VIP- and PACAP-deficient mice
    • Girard BA, et al. (2006) Noncompensation in peptide/receptor gene expression and distinct behavioral phenotypes in VIP- and PACAP-deficient mice. J Neurochem 99:499-513.
    • (2006) J Neurochem , vol.99 , pp. 499-513
    • Girard, B.A.1
  • 22
    • 33745024475 scopus 로고    scopus 로고
    • Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity
    • Alonso AC, Li B, Grundke-Iqbal I, Iqbal K (2006) Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity. Proc Natl Acad Sci USA 103:8864-8869.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 8864-8869
    • Alonso, A.C.1    Li, B.2    Grundke-Iqbal, I.3    Iqbal, K.4
  • 23
    • 33750466222 scopus 로고    scopus 로고
    • Microtubule: A common target for parkin and Parkinson's disease toxins
    • Feng J (2006) Microtubule: A common target for parkin and Parkinson's disease toxins. Neuroscientist 12:469-476.
    • (2006) Neuroscientist , vol.12 , pp. 469-476
    • Feng, J.1
  • 24
    • 38349061552 scopus 로고    scopus 로고
    • The N-terminus of PrP is responsible for interacting with tubulin and fCJD related PrP mutants possess stronger inhibitive effect on microtubule assembly in vitro
    • Dong CF, et al. (2008) The N-terminus of PrP is responsible for interacting with tubulin and fCJD related PrP mutants possess stronger inhibitive effect on microtubule assembly in vitro. Arch Biochem Biophys 470:83-92.
    • (2008) Arch Biochem Biophys , vol.470 , pp. 83-92
    • Dong, C.F.1
  • 25
    • 33645078104 scopus 로고    scopus 로고
    • Dystonia-causing mutant torsinA inhibits cell adhesion and neurite extension through interference with cytoskeletal dynamics
    • Hewett JW, Zeng J, Niland BP, Bragg DC, Breakefield XO (2006) Dystonia-causing mutant torsinA inhibits cell adhesion and neurite extension through interference with cytoskeletal dynamics. Neurobiol Dis 22:98-111.
    • (2006) Neurobiol Dis , vol.22 , pp. 98-111
    • Hewett, J.W.1    Zeng, J.2    Niland, B.P.3    Bragg, D.C.4    Breakefield, X.O.5
  • 26
    • 0029948062 scopus 로고    scopus 로고
    • Transient encephalopathy after paclitaxel (Taxol) infusion
    • Perry JR, Warner E (1996) Transient encephalopathy after paclitaxel (Taxol) infusion. Neurology 46:1596-1599.
    • (1996) Neurology , vol.46 , pp. 1596-1599
    • Perry, J.R.1    Warner, E.2
  • 27
    • 33750134831 scopus 로고    scopus 로고
    • Differences in behavioural test battery performance between mice with hippocampal and cerebellar lesions
    • Goddyn H, Leo S, Meert T, D'Hooge R (2006) Differences in behavioural test battery performance between mice with hippocampal and cerebellar lesions. Behav. Brain Res 173:138-147.
    • (2006) Behav. Brain Res , vol.173 , pp. 138-147
    • Goddyn, H.1    Leo, S.2    Meert, T.3    D'Hooge, R.4
  • 28
    • 0034792085 scopus 로고    scopus 로고
    • Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity
    • Rios M, et al. (2001) Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Mol Endocrinol 15:1748-1757.
    • (2001) Mol Endocrinol , vol.15 , pp. 1748-1757
    • Rios, M.1
  • 29
    • 33748280959 scopus 로고    scopus 로고
    • Transgenic mice overexpressing glycogen synthase kinase 3beta: A putative model of hyperactivity and mania
    • Prickaerts J, et al. (2006) Transgenic mice overexpressing glycogen synthase kinase 3beta: a putative model of hyperactivity and mania. J Neurosci 26:9022-9029.
    • (2006) J Neurosci , vol.26 , pp. 9022-9029
    • Prickaerts, J.1
  • 30
    • 9244235981 scopus 로고    scopus 로고
    • A possible mechanism for the action of adrenomedullin in brain to stimulate stress hormone secretion
    • Taylor MM, Samson WK (2004) A possible mechanism for the action of adrenomedullin in brain to stimulate stress hormone secretion. Endocrinology 145:4890-4896.
    • (2004) Endocrinology , vol.145 , pp. 4890-4896
    • Taylor, M.M.1    Samson, W.K.2
  • 31
    • 39049191920 scopus 로고    scopus 로고
    • Effects of proadrenomedullin N-terminal 20 peptide on the rat pituitary-adrenocortical axis under basal and stressful conditions
    • Malendowicz LK, Macchi C, Nowak M, Nussdorfer GG, Majchrzak M (2006) Effects of proadrenomedullin N-terminal 20 peptide on the rat pituitary-adrenocortical axis under basal and stressful conditions. Int J Mol Med 18:285-287.
    • (2006) Int J Mol Med , vol.18 , pp. 285-287
    • Malendowicz, L.K.1    Macchi, C.2    Nowak, M.3    Nussdorfer, G.G.4    Majchrzak, M.5
  • 32
    • 0035953170 scopus 로고    scopus 로고
    • Distribution of preproadrenomedullin mRNA in the rat central nervous system and its modulation by physiological stressors
    • Shan J, Krukoff TL (2001) Distribution of preproadrenomedullin mRNA in the rat central nervous system and its modulation by physiological stressors. J Comp Neurol 432:88-100.
    • (2001) J Comp Neurol , vol.432 , pp. 88-100
    • Shan, J.1    Krukoff, T.L.2
  • 33
    • 15544371136 scopus 로고    scopus 로고
    • Neurohormonal changes in medical students during academic stress
    • Al-Ayadhi LY (2005) Neurohormonal changes in medical students during academic stress. Ann Saudi Med 25:36-40.
    • (2005) Ann Saudi Med , vol.25 , pp. 36-40
    • Al-Ayadhi, L.Y.1
  • 34
    • 27744495062 scopus 로고    scopus 로고
    • Ether stress increases adrenomedullin gene expression and levels in the rat adrenal
    • Tang F, Wong MP, Hwang IS, Li YY (2005) Ether stress increases adrenomedullin gene expression and levels in the rat adrenal. Horm Metab Res 37:585-588.
    • (2005) Horm Metab Res , vol.37 , pp. 585-588
    • Tang, F.1    Wong, M.P.2    Hwang, I.S.3    Li, Y.Y.4
  • 35
    • 33748092384 scopus 로고    scopus 로고
    • Animal models of obsessive-compulsive disorder: Rationale to understanding psychobiology and pharmacology
    • Korff S, Harvey BH (2006) Animal models of obsessive-compulsive disorder: Rationale to understanding psychobiology and pharmacology. Psychiatr Clin North Am 29:371-390.
    • (2006) Psychiatr Clin North Am , vol.29 , pp. 371-390
    • Korff, S.1    Harvey, B.H.2
  • 36
    • 34548649412 scopus 로고    scopus 로고
    • Mortality, oxidative stress and tau accumulation during ageing in parkin null mice
    • Rodriguez-Navarro JA, et al. (2007) Mortality, oxidative stress and tau accumulation during ageing in parkin null mice. J Neurochem 103:98-114.
    • (2007) J Neurochem , vol.103 , pp. 98-114
    • Rodriguez-Navarro, J.A.1
  • 37
    • 32844458762 scopus 로고    scopus 로고
    • Age-dependent measures of anxiety and cognition in male histidine decarboxylase knockout (Hdc-/-) mice
    • Acevedo SF, Ohtsu H, Benice TS, Rizk-Jackson A, Raber J (2006) Age-dependent measures of anxiety and cognition in male histidine decarboxylase knockout (Hdc-/-) mice. Brain Res 1071:113-123.
    • (2006) Brain Res , vol.1071 , pp. 113-123
    • Acevedo, S.F.1    Ohtsu, H.2    Benice, T.S.3    Rizk-Jackson, A.4    Raber, J.5
  • 38
    • 33645741604 scopus 로고    scopus 로고
    • Sterol regulatory element binding protein (SREBP)-1 expression in brain is affected by age but not by hormones or metabolic changes
    • Okamoto K, et al. (2006) Sterol regulatory element binding protein (SREBP)-1 expression in brain is affected by age but not by hormones or metabolic changes. Brain Res 1081:19-27.
    • (2006) Brain Res , vol.1081 , pp. 19-27
    • Okamoto, K.1
  • 39
    • 34547107623 scopus 로고    scopus 로고
    • Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age
    • Dackor R, Fritz-Six K, Smithies O, Caron K (2007) Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age. J Biol Chem 282:18094-18099.
    • (2007) J Biol Chem , vol.282 , pp. 18094-18099
    • Dackor, R.1    Fritz-Six, K.2    Smithies, O.3    Caron, K.4
  • 40
    • 38749100559 scopus 로고    scopus 로고
    • Effect of aging on the expression of adrenomedullin and its receptor component proteins in the male reproductive system of the rat
    • Li YY, Wai-Sum O, Tang F (2007) Effect of aging on the expression of adrenomedullin and its receptor component proteins in the male reproductive system of the rat. J Gerontol A Biol Sci Med Sci 62:1346-1351.
    • (2007) J Gerontol A Biol Sci Med Sci , vol.62 , pp. 1346-1351
    • Li, Y.Y.1    Wai-Sum, O.2    Tang, F.3
  • 41
    • 34047182083 scopus 로고    scopus 로고
    • Age-related changes in adrenomedullin expression and hypoxia-inducible factor-1 activity in the rat lung and their responses to hypoxia
    • Hwang IS, Fung ML, Liong EC, Tipoe GL, Tang F (2007) Age-related changes in adrenomedullin expression and hypoxia-inducible factor-1 activity in the rat lung and their responses to hypoxia. J Gerontol A Biol Sci Med Sci 62:41-49.
    • (2007) J Gerontol A Biol Sci Med Sci , vol.62 , pp. 41-49
    • Hwang, I.S.1    Fung, M.L.2    Liong, E.C.3    Tipoe, G.L.4    Tang, F.5
  • 42
    • 30444438526 scopus 로고    scopus 로고
    • Postischemic infusion of adrenomedullin protects against ischemic stroke by inhibiting apoptosis and promoting angiogenesis
    • Xia CF, Yin H, Borlongan CV, Chao J, Chao L (2006) Postischemic infusion of adrenomedullin protects against ischemic stroke by inhibiting apoptosis and promoting angiogenesis. Exp Neurol 197:521-530.
    • (2006) Exp Neurol , vol.197 , pp. 521-530
    • Xia, C.F.1    Yin, H.2    Borlongan, C.V.3    Chao, J.4    Chao, L.5
  • 43
    • 22044433057 scopus 로고    scopus 로고
    • Adrenomedullin protects rat cerebral endothelial cells from oxidant damage in vitro
    • Chen L, Kis B, Busija DW, Yamashita H, Ueta Y (2005) Adrenomedullin protects rat cerebral endothelial cells from oxidant damage in vitro. Regul Pept 130:27-34.
    • (2005) Regul Pept , vol.130 , pp. 27-34
    • Chen, L.1    Kis, B.2    Busija, D.W.3    Yamashita, H.4    Ueta, Y.5
  • 44
    • 0035227286 scopus 로고    scopus 로고
    • Manipulating mouse embryonic stem cells
    • Tessarollo L (2001) Manipulating mouse embryonic stem cells. Methods Mol Biol 158:47-63.
    • (2001) Methods Mol Biol , vol.158 , pp. 47-63
    • Tessarollo, L.1
  • 45
    • 0035227275 scopus 로고    scopus 로고
    • Isolation, microinjection, and transfer of mouse blastocysts
    • Bonin A, Reid SW, Tessarollo L (2001) Isolation, microinjection, and transfer of mouse blastocysts. Methods Mol Biol 158:121-134.
    • (2001) Methods Mol Biol , vol.158 , pp. 121-134
    • Bonin, A.1    Reid, S.W.2    Tessarollo, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.