Human genomic disease variants: A neutral evolutionary explanation

Genome Research

Volumn 22, Issue 8, 2012, Pages 1383-1394

  Dudley, Joel T ^a,b   Kim, Yuseob ^c,d   Liu, Li ^d   Markov, Glenn J ^a,d   Gerold, Kristyn ^d   Chen, Rong ^a   Butte, Atul J ^a,b   Kumar, Sudhir ^d,e  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LUCILE PACKARD CHILDREN S HOSPITAL   (United States)

^c Ewha Womans University   (South Korea)

^d ARIZONA STATE UNIVERSITY   (United States)

^e ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; CONCEPTUAL FRAMEWORK; GENE FREQUENCY; GENE MUTATION; GENETIC DRIFT; GENETIC RECOMBINATION; GENETIC VARIABILITY; HEALTH; HUMAN; LIFESPAN; MEDICINE; MOLECULAR EVOLUTION; NEUTRAL THEORY OF MOLECULAR EVOLUTION; PRIORITY JOURNAL; REVIEW; SPECIES DIFFERENCE;

ADAPTATION, BIOLOGICAL; ALLELES; EVOLUTION, MOLECULAR; GENE FREQUENCY; GENETIC DISEASES, INBORN; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENETICS, POPULATION; GENOME, HUMAN; HUMANS; MOLECULAR MEDICINE; SELECTION, GENETIC;

EID: 84864616473     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.133702.111     Document Type: Review

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