-
1
-
-
85045827427
-
Migration out of Africa
-
Maddox J (1994) Migration out of Africa. Nature 372: 32.
-
(1994)
Nature
, vol.372
, pp. 32
-
-
Maddox, J.1
-
2
-
-
33745121154
-
Positive natural selection in the human lineage
-
Sabeti PC, Schaffner SF, Fry B, Lohmueller J, Varilly P, et al. (2006) Positive natural selection in the human lineage. Science 312: 1614-1620.
-
(2006)
Science
, vol.312
, pp. 1614-1620
-
-
Sabeti, P.C.1
Schaffner, S.F.2
Fry, B.3
Lohmueller, J.4
Varilly, P.5
-
3
-
-
0036139250
-
Molecular analysis of the beta-globin gene cluster in the Niokholo Mandenka population reveals a recent origin of the beta(S) Senegal mutation
-
Currat M, Trabuchet G, Rees D, Perrin P, Harding RM, et al. (2002) Molecular analysis of the beta-globin gene cluster in the Niokholo Mandenka population reveals a recent origin of the beta(S) Senegal mutation. Am J Hum Genet 70: 207-223.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 207-223
-
-
Currat, M.1
Trabuchet, G.2
Rees, D.3
Perrin, P.4
Harding, R.M.5
-
4
-
-
56049092769
-
Hitchhiking both ways: Effect of two interfering selective sweeps on linked neutral variation
-
Chevin LM, Billiard S, Hospital F (2008) Hitchhiking both ways: effect of two interfering selective sweeps on linked neutral variation. Genetics 180: 301-316.
-
(2008)
Genetics
, vol.180
, pp. 301-316
-
-
Chevin, L.M.1
Billiard, S.2
Hospital, F.3
-
6
-
-
65249131713
-
Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes
-
Nejentsev S, Walker N, Riches D, Egholm M, Todd JA (2009) Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes. Science 324: 387-389.
-
(2009)
Science
, vol.324
, pp. 387-389
-
-
Nejentsev, S.1
Walker, N.2
Riches, D.3
Egholm, M.4
Todd, J.A.5
-
7
-
-
0027050163
-
Geographic distribution of rheumatoid arthritis in ancient North America: Implications for pathogenesis
-
Rothschild BM, Woods RJ, Rothschild C, Sebes JI (1992) Geographic distribution of rheumatoid arthritis in ancient North America: implications for pathogenesis. Semin Arthritis Rheum 22: 181-187.
-
(1992)
Semin Arthritis Rheum
, vol.22
, pp. 181-187
-
-
Rothschild, B.M.1
Woods, R.J.2
Rothschild, C.3
Sebes, J.I.4
-
8
-
-
45449101500
-
Natural selection on genes that underlie human disease susceptibility
-
Blekhman R, Man O, Herrmann L, Boyko AR, Indap A, et al. (2008) Natural selection on genes that underlie human disease susceptibility. Curr Biol 18: 883-889.
-
(2008)
Curr Biol
, vol.18
, pp. 883-889
-
-
Blekhman, R.1
Man, O.2
Herrmann, L.3
Boyko, A.R.4
Indap, A.5
-
9
-
-
1942500217
-
Is rheumatoid arthritis a consequence of natural selection for enhanced tuberculosis resistance?
-
Mobley JL (2004) Is rheumatoid arthritis a consequence of natural selection for enhanced tuberculosis resistance? Med Hypotheses 62: 839-843.
-
(2004)
Med Hypotheses
, vol.62
, pp. 839-843
-
-
Mobley, J.L.1
-
10
-
-
63749127623
-
Worldwide population differentiation at disease-associated SNPs
-
Myles S, Davison D, Barrett J, Stoneking M, Timpson N (2008) Worldwide population differentiation at disease-associated SNPs. BMC Med Genomics 1: 22.
-
(2008)
BMC Med Genomics
, vol.1
, pp. 22
-
-
Myles, S.1
Davison, D.2
Barrett, J.3
Stoneking, M.4
Timpson, N.5
-
11
-
-
7444227970
-
Coding single-nucleotide polymorphisms associated with complex vs. Mendelian disease: Evolutionary evidence for differences in molecular effects
-
Thomas PD, Kejariwal A (2004) Coding single-nucleotide polymorphisms associated with complex vs. Mendelian disease: evolutionary evidence for differences in molecular effects. Proc Natl Acad Sci U S A 101: 15398-15403.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 15398-15403
-
-
Thomas, P.D.1
Kejariwal, A.2
-
12
-
-
33750935988
-
Population genetics models of common diseases
-
Di Rienzo A (2006) Population genetics models of common diseases. Curr Opin Genet Dev 16: 630-636.
-
(2006)
Curr Opin Genet Dev
, vol.16
, pp. 630-636
-
-
di Rienzo, A.1
-
13
-
-
33646488359
-
Selective pressures at a codon-level predict deleterious mutations in human disease genes
-
Arbiza L, Duchi S, Montaner D, Burguet J, Pantoja-Uceda D, et al. (2006) Selective pressures at a codon-level predict deleterious mutations in human disease genes. J Mol Biol 358: 1390-1404.
-
(2006)
J Mol Biol
, vol.358
, pp. 1390-1404
-
-
Arbiza, L.1
Duchi, S.2
Montaner, D.3
Burguet, J.4
Pantoja-Uceda, D.5
-
15
-
-
74249098458
-
Autoimmune disease classification by inverse association with SNP alleles
-
Sirota M, Schaub MA, Batzoglou S, Robinson WH, Butte AJ (2009) Autoimmune disease classification by inverse association with SNP alleles. PLoS Genet 5: e1000792.
-
(2009)
PLoS Genet
, vol.5
-
-
Sirota, M.1
Schaub, M.A.2
Batzoglou, S.3
Robinson, W.H.4
Butte, A.J.5
-
16
-
-
35349012592
-
Genomewide detection and characterization of positive selection in human populations
-
Sabeti PC, Varilly P, Fry B, Lohmueller J, Hostetter E, et al. (2007) Genomewide detection and characterization of positive selection in human populations. Nature 449: 913-918.
-
(2007)
Nature
, vol.449
, pp. 913-918
-
-
Sabeti, P.C.1
Varilly, P.2
Fry, B.3
Lohmueller, J.4
Hostetter, E.5
-
17
-
-
77952309062
-
Exploring the differences in evolutionary rates between monogenic and polygenic disease genes in human
-
Podder S, Ghosh TC (2009) Exploring the differences in evolutionary rates between monogenic and polygenic disease genes in human. Mol Biol Evol 27: 934-941.
-
(2009)
Mol Biol Evol
, vol.27
, pp. 934-941
-
-
Podder, S.1
Ghosh, T.C.2
-
18
-
-
77956341183
-
Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes
-
Guinan KJ, Cunningham RT, Meenagh A, Gonzalez A, Dring MM, et al. (2010) Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes. Genes Immun.
-
(2010)
Genes Immun
-
-
Guinan, K.J.1
Cunningham, R.T.2
Meenagh, A.3
Gonzalez, A.4
Dring, M.M.5
-
19
-
-
77955090515
-
Both Noncoding and Protein-Coding RNAs Contribute to Gene Expression Evolution in the Primate Brain
-
Babbitt CC, Fedrigo O, Pfefferle AD, Boyle AP, Horvath JE, et al. (2010) Both Noncoding and Protein-Coding RNAs Contribute to Gene Expression Evolution in the Primate Brain. Genome Biol Evol 2010. pp 67-79.
-
(2010)
Genome Biol Evol
, vol.2010
, pp. 67-79
-
-
Babbitt, C.C.1
Fedrigo, O.2
Pfefferle, A.D.3
Boyle, A.P.4
Horvath, J.E.5
-
20
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
The Wellcome Trust Case Control Consortium
-
The Wellcome Trust Case Control Consortium (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447: 661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
21
-
-
0037167852
-
Detecting recent positive selection in the human genome from haplotype structure
-
Sabeti PC, Reich DE, Higgins JM, Levine HZ, Richter DJ, et al. (2002) Detecting recent positive selection in the human genome from haplotype structure. Nature 419: 832-837.
-
(2002)
Nature
, vol.419
, pp. 832-837
-
-
Sabeti, P.C.1
Reich, D.E.2
Higgins, J.M.3
Levine, H.Z.4
Richter, D.J.5
-
22
-
-
66449116276
-
The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes
-
Richardson SJ, Willcox A, Bone AJ, Foulis AK, Morgan NG (2009) The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes. Diabetologia 52: 1143-1151.
-
(2009)
Diabetologia
, vol.52
, pp. 1143-1151
-
-
Richardson, S.J.1
Willcox, A.2
Bone, A.J.3
Foulis, A.K.4
Morgan, N.G.5
-
23
-
-
22244454407
-
Risk and case characteristics of tuberculosis in rheumatoid arthritis associated with tumor necrosis factor antagonists in Sweden
-
Askling J, Fored CM, Brandt L, Baecklund E, Bertilsson L, et al. (2005) Risk and case characteristics of tuberculosis in rheumatoid arthritis associated with tumor necrosis factor antagonists in Sweden. Arthritis Rheum 52: 1986-1992.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1986-1992
-
-
Askling, J.1
Fored, C.M.2
Brandt, L.3
Baecklund, E.4
Bertilsson, L.5
-
24
-
-
22544445912
-
Tumor necrosis factor inhibition and invasive fungal infections
-
Filler SG, Yeaman MR, Sheppard DC (2005) Tumor necrosis factor inhibition and invasive fungal infections. Clin Infect Dis 41 Suppl 3: S208-212.
-
(2005)
Clin Infect Dis
, vol.41
, Issue.SUPPL. 3
-
-
Filler, S.G.1
Yeaman, M.R.2
Sheppard, D.C.3
-
25
-
-
17344370929
-
Reactivation of brucellosis after treatment with infliximab in a patient with rheumatoid arthritis
-
Jimenez FG, Colmenero JD, Irigoyen MV (2005) Reactivation of brucellosis after treatment with infliximab in a patient with rheumatoid arthritis. J Infect 50: 370-371.
-
(2005)
J Infect
, vol.50
, pp. 370-371
-
-
Jimenez, F.G.1
Colmenero, J.D.2
Irigoyen, M.V.3
-
26
-
-
3242890260
-
Tuberculosis associated with blocking agents against tumor necrosis factor-alpha-California, 2002-2003
-
Center for Disease Control and Prevention
-
Center for Disease Control and Prevention (2004) Tuberculosis associated with blocking agents against tumor necrosis factor-alpha-California, 2002-2003. MMWR Morb Mortal Wkly Rep 53: 683-686.
-
(2004)
MMWR Morb Mortal Wkly Rep
, vol.53
, pp. 683-686
-
-
-
27
-
-
28844465657
-
Primary cutaneous Nocardia otitidiscaviarum infection in a patient with rheumatoid arthritis treated with infliximab
-
Fabre S, Gibert C, Lechiche C, Jorgensen C, Sany J (2005) Primary cutaneous Nocardia otitidiscaviarum infection in a patient with rheumatoid arthritis treated with infliximab. J Rheumatol 32: 2432-2433.
-
(2005)
J Rheumatol
, vol.32
, pp. 2432-2433
-
-
Fabre, S.1
Gibert, C.2
Lechiche, C.3
Jorgensen, C.4
Sany, J.5
-
28
-
-
61849117976
-
Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/ TNFAIP3 as a susceptibility locus
-
Fung EY, Smyth DJ, Howson JM, Cooper JD, Walker NM, et al. (2009) Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/ TNFAIP3 as a susceptibility locus. Genes Immun 10: 188-191.
-
(2009)
Genes Immun
, vol.10
, pp. 188-191
-
-
Fung, E.Y.1
Smyth, D.J.2
Howson, J.M.3
Cooper, J.D.4
Walker, N.M.5
-
29
-
-
66349105445
-
A Classifierbased approach to identify genetic similarities between diseases
-
Schaub MA, Kaplow IM, Sirota M, Do CB, Butte AJ, et al. (2009) A Classifierbased approach to identify genetic similarities between diseases. Bioinformatics 25: i21-29.
-
(2009)
Bioinformatics
, vol.25
-
-
Schaub, M.A.1
Kaplow, I.M.2
Sirota, M.3
Do, C.B.4
Butte, A.J.5
-
30
-
-
0035034523
-
Historical origins of current IBD concepts
-
Kirsner JB (2001) Historical origins of current IBD concepts. World J Gastroenterol 7: 175-184.
-
(2001)
World J Gastroenterol
, vol.7
, pp. 175-184
-
-
Kirsner, J.B.1
-
31
-
-
0043267974
-
Haplotype blocks and linkage disequilibrium in the human genome
-
Wall JD, Pritchard JK (2003) Haplotype blocks and linkage disequilibrium in the human genome. Nat Rev Genet 4: 587-597.
-
(2003)
Nat Rev Genet
, vol.4
, pp. 587-597
-
-
Wall, J.D.1
Pritchard, J.K.2
-
32
-
-
33644522070
-
Searching for signals of evolutionary selection in 168 genes related to immune function
-
Walsh EC, Sabeti P, Hutcheson HB, Fry B, Schaffner SF, et al. (2006) Searching for signals of evolutionary selection in 168 genes related to immune function. Hum Genet 119: 92-102.
-
(2006)
Hum Genet
, vol.119
, pp. 92-102
-
-
Walsh, E.C.1
Sabeti, P.2
Hutcheson, H.B.3
Fry, B.4
Schaffner, S.F.5
-
33
-
-
40049107734
-
Molecular population genetics of PCSK9: A signature of recent positive selection
-
Ding K, Kullo IJ (2008) Molecular population genetics of PCSK9: a signature of recent positive selection. Pharmacogenet Genomics 18: 169-179.
-
(2008)
Pharmacogenet Genomics
, vol.18
, pp. 169-179
-
-
Ding, K.1
Kullo, I.J.2
-
34
-
-
33846301634
-
Signatures of strong population differentiation shape extended haplotypes across the human CD28, CTLA4, and ICOS costimulatory genes
-
Butty V, Roy M, Sabeti P, Besse W, Benoist C, et al. (2007) Signatures of strong population differentiation shape extended haplotypes across the human CD28, CTLA4, and ICOS costimulatory genes. Proc Natl Acad Sci U S A 104: 570-575.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 570-575
-
-
Butty, V.1
Roy, M.2
Sabeti, P.3
Besse, W.4
Benoist, C.5
-
35
-
-
79959503826
-
The International HapMap Project
-
The International Hap Map Consortium
-
The International Hap Map Consortium (2003) The International HapMap Project. Nature 426: 789-796.
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
-
36
-
-
12744253764
-
HapBlock: Haplotype block partitioning and tag SNP selection software using a set of dynamic programming algorithms
-
Zhang K, Qin Z, Chen T, Liu JS, Waterman MS, et al. (2005) HapBlock: haplotype block partitioning and tag SNP selection software using a set of dynamic programming algorithms. Bioinformatics 21: 131-134.
-
(2005)
Bioinformatics
, vol.21
, pp. 131-134
-
-
Zhang, K.1
Qin, Z.2
Chen, T.3
Liu, J.S.4
Waterman, M.S.5
-
37
-
-
0035941029
-
Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21
-
Patil N, Berno AJ, Hinds DA, Barrett WA, Doshi JM, et al. (2001) Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21. Science 294: 1719-1723.
-
(2001)
Science
, vol.294
, pp. 1719-1723
-
-
Patil, N.1
Berno, A.J.2
Hinds, D.A.3
Barrett, W.A.4
Doshi, J.M.5
-
38
-
-
0035173378
-
dbSNP: The NCBI database of genetic variation
-
Sherry ST, Ward MH, Kholodov M, Baker J, Phan L, et al. (2001) dbSNP: the NCBI database of genetic variation. Nucleic Acids Res 29: 308-311.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 308-311
-
-
Sherry, S.T.1
Ward, M.H.2
Kholodov, M.3
Baker, J.4
Phan, L.5
-
39
-
-
33749416027
-
The influence of recombination on human genetic diversity
-
Spencer CC, Deloukas P, Hunt S, Mullikin J, Myers S, et al. (2006) The influence of recombination on human genetic diversity. PLoS Genet 2: e148.
-
(2006)
PLoS Genet
, vol.2
-
-
Spencer, C.C.1
Deloukas, P.2
Hunt, S.3
Mullikin, J.4
Myers, S.5
|