Positional conservation and amino acids shape the correct diagnosis and population frequencies of benign and damaging personal amino acid mutations

Genome Research

Volumn 19, Issue 9, 2009, Pages 1562-1569

  Kumar, Sudhir ^a,b   Suleski, Michael P ^a   Markov, Glenn J ^a   Lawrence, Simon ^a   Marco, Antonio ^a   Filipski, Alan J ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID;

ALLELE; ARTICLE; DNA SEQUENCE; EVOLUTIONARY RATE; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; GENE FREQUENCY; GENE FUNCTION; GENETIC CONSERVATION; HUMAN; HUMAN GENOME; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; VERTEBRATE;

AMINO ACID SUBSTITUTION; AMINO ACIDS; COMPUTATIONAL BIOLOGY; EVOLUTION, MOLECULAR; GENE FREQUENCY; GENETIC DISEASES, INBORN; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; HUMANS; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE;

VERTEBRATA;

EID: 69749093207     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.091991.109     Document Type: Article

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