Human non-synonymous SNPs: Server and survey

Nucleic Acids Research

Volumn 30, Issue 17, 2002, Pages 3894-3900

  Ramensky, Vasily ^a,b,c   Bork, Peer ^a,b   Sunyaev, Shamil ^a,c,d  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DATA ANALYSIS; DATA BASE; INTERNET; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION REGULATION;

EID: 0036713510     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkf493     Document Type: Article

References (37)

1. The future of genetic studies of complex human diseases
2. Searching for genetic determinants in the new millennium
3. A 4-Mb high-density single nucleotide polymorphism-based map around human APOE
4. SNP association studies in Alzheimer's disease highlight problem for complex disease analysis
5. Single nucleotide polymorphisms and the future of genetic epidemiology
6. Towards a structural basis of human non-synonymous single nucleotide polymorphisms
7. Prediction of deleterious human alleles
8. SNPs, protein structure and disease
9. Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: Structure-based assessment of amino acid variation
10. Predicting deleterious amino acid substitutions
11. Characterization of disease-associated single amino acid polymorphisms in terms of sequence and structure properties
12. SNP frequencies in human genes: An excess of rare alleles and differing modes of selection
13. HGVbase: A human sequence variation database emphasizing data quality and a broad spectrum of data sources
14. Strategies in complex disease mapping
15. Protein sequence databases
16. Statistics of local complexity in amino-acid-sequences and sequence databases
17. Information enhancement methods for large-scale sequence analysis
18. Repbase update: A database and an electronic journal of repetitive elements
19. Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes
20. Predicting coiled coils from protein sequences
21. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
22. PHAT: A transmembrane-specific substitution matrix. Predicted hydrophobic and transmembrane
23. Basic local alignment search tool
24. PSIC: Profile extraction from sequence alignments with position-specific counts of independent observations
25. The Protein Data Bank
26. PQS: A protein quaternary structure file server
27. Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features
28. Satisfying hydrogen bonding potential in proteins
29. Characterization of single-nucleotide polymorphisms in coding regions of human genes
30. Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis
31. Sequence diversity in 36 candidate genes for cardiovascular disorders
32. Protein dispensability and rate of evolution
33. SCOP database in 2002: Refinements accommodate structural genomics
34. Creating the gene ontology resource: Design and implementation
35. The molecular basis of dominance
36. How many diseases does it take to map a gene with SNPs?
37. Positive and negative selection on the human genome