Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change

Molecular Biology and Evolution

Volumn 26, Issue 9, 2009, Pages 2097-2108

  Eyre Walker, Adam ^a   Keightley, Peter D ^b  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Adaptation; Drosophila; Humans; Nucleotide polymorphism; Site frequency spectrum

Indexed keywords

AMINO ACID; DNA; PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; DROSOPHILA; EFFECTIVE POPULATION SIZE; GENE DELETION; GENETIC DRIFT; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; INTRON; MACACA; MOLECULAR EVOLUTION; MUTATION; NONHUMAN; POPULATION SIZE;

ADAPTATION, PHYSIOLOGICAL; AMINO ACID SUBSTITUTION; ANIMALS; BIAS (EPIDEMIOLOGY); COMPUTER SIMULATION; DATABASES, GENETIC; DNA, INTERGENIC; DROSOPHILA; EVOLUTION, MOLECULAR; HUMANS; LIKELIHOOD FUNCTIONS; MACACA; MODELS, GENETIC; MUTATION; OPEN READING FRAMES; POPULATION DENSITY; RECOMBINATION, GENETIC;

HOMINIDAE;

EID: 68949202924     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msp119     Document Type: Article

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