Ancient and recent positive selection transformed opioid cis-regulation in humans

PLoS Biology

Volumn 3, Issue 12, 2005, Pages 1-12

  Rockman, Matthew V ^a,e   Hahn, Matthew W ^a,b,f   Soranzo, Nicole ^c   Zimprich, Fritz ^d   Goldstein, David B ^a,c   Wray, Gregory A ^a  

^a DUKE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e PRINCETON UNIVERSITY   (United States)

^f INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OPIATE RECEPTOR; PRODYNORPHIN; BIOLOGICAL MARKER; ENKEPHALIN; NARCOTIC AGENT; PREPROENKEPHALIN; PROTEIN PRECURSOR;

ALLELE; ARTICLE; CONVERGENT EVOLUTION; GENE CONTROL; GENE FREQUENCY; GENETIC SELECTION; GENETIC TRANSFORMATION; MOLECULAR EVOLUTION; NATURAL SELECTION; PHYLOGENETIC TREE; PROMOTER REGION; SPECIES CONSERVATION; TRANSCRIPTION INITIATION; ANIMAL; GENE EXPRESSION REGULATION; GENETIC VARIABILITY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PHYLOGENY; SEQUENCE ALIGNMENT;

PAN TROGLODYTES;

ALLELES; ANIMALS; BASE SEQUENCE; BIOLOGICAL MARKERS; CONSERVED SEQUENCE; ENKEPHALINS; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; NARCOTICS; PHYLOGENY; PROMOTER REGIONS (GENETICS); PROTEIN PRECURSORS; SELECTION (GENETICS); SEQUENCE ALIGNMENT; VARIATION (GENETICS);

EID: 29144492108     PISSN: 15457885     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0030387     Document Type: Article

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