-
1
-
-
78751644048
-
Amyloid-beta and tau-a toxic pas de deux in Alzheimer ' s disease
-
Ittner LM, Gotz J. Amyloid-beta and tau-a toxic pas de deux in Alzheimer ' s disease. Nat Rev Neurosci 2011;12:65-72.
-
(2011)
Nat Rev Neurosci
, vol.12
, pp. 65-72
-
-
Ittner, L.M.1
Gotz, J.2
-
3
-
-
84863262231
-
MTOR is a potential therapeutic target for Alzhiemer ' s disease
-
Sun M-K, editor Hauppauge, NY: Nova Science Publishers, Inc. in press
-
Santos RX, Moreira PI. mTOR is a potential therapeutic target for Alzhiemer ' s disease. In: Sun M-K, editor. Cognitive Sciences. Hauppauge, NY: Nova Science Publishers, Inc.; 2012. in press.
-
(2012)
Cognitive Sciences
-
-
Santos, R.X.1
Moreira, P.I.2
-
4
-
-
79960345867
-
Genetics: Fi nding risk factors
-
Eisenstein M. Genetics: fi nding risk factors. Nature 2011; 475:S20-S22.
-
(2011)
Nature
, vol.475
-
-
Eisenstein, M.1
-
5
-
-
77956224679
-
The Alzheimer' s disease mitochondrial cascade hypothesis
-
Swerdlow RH, Burns JM, Khan SM. The Alzheimer' s disease mitochondrial cascade hypothesis. J Alzheimers Dis 2010;20(Suppl 2):S265-279.
-
(2010)
J Alzheimers Dis
, vol.20
, Issue.SUPPL. 2
-
-
Swerdlow, R.H.1
Burns, J.M.2
Khan, S.M.3
-
6
-
-
77956026971
-
Alzheimer ' s disease: Diverse aspects of mitochondrial malfunctioning
-
Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. Alzheimer ' s disease: diverse aspects of mitochondrial malfunctioning. Int J Clin Exp Pathol 2010;3:570-581.
-
(2010)
Int J Clin Exp Pathol
, vol.3
, pp. 570-581
-
-
Santos, R.X.1
Correia, S.C.2
Wang, X.3
Perry, G.4
Smith, M.A.5
Moreira, P.I.6
Zhu, X.7
-
7
-
-
33646144212
-
Redox proteomics identifi cation of oxidatively modifi ed hippocampal proteins in mild cognitive impairment: Insights into the development of Alzheimer ' s disease
-
Butterfi eld DA, Poon HF, St Clair D, Keller JN, Pierce WM, Klein JB, Markesbery WR. Redox proteomics identifi cation of oxidatively modifi ed hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer ' s disease. Neurobiol Dis 2006;22:223-232.
-
(2006)
Neurobiol Dis
, vol.22
, pp. 223-232
-
-
Butterfield, D.A.1
Poon, H.F.2
St Clair, D.3
Keller, J.N.4
Pierce, W.M.5
Klein, J.B.6
Markesbery, W.R.7
-
8
-
-
27144494994
-
Ribosome dysfunction is an early event in Alzheimer's disease
-
DOI 10.1523/JNEUROSCI.3040-05.2005
-
Ding Q, Markesbery WR, Chen Q, Li F, Keller JN. Ribosome dysfunction is an early event in Alzheimer ' s disease. J Neurosci 2005;25:9171-9175. (Pubitemid 41500825)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.40
, pp. 9171-9175
-
-
Ding, Q.1
Markesbery, W.R.2
Chen, Q.3
Li, F.4
Keller, J.N.5
-
9
-
-
16844382331
-
Evidence of increased oxidative damage in subjects with mild cognitive impairment
-
Keller JN, Schmitt FA, Scheff SW, Ding Q, Chen Q, Butterfi eld DA, Markesbery WR. Evidence of increased oxidative damage in subjects with mild cognitive impairment. Neurology 2005;64:1152-1156.
-
(2005)
Neurology
, vol.64
, pp. 1152-1156
-
-
Keller, J.N.1
Schmitt, F.A.2
Scheff, S.W.3
Ding, Q.4
Chen, Q.5
Butterfield, D.A.6
Markesbery, W.R.7
-
10
-
-
27644446857
-
Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment
-
DOI 10.1002/ana.20629
-
Markesbery WR, Kryscio RJ, Lovell MA, Morrow JD. Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment. Ann Neurol 2005;58:730-735. (Pubitemid 41552548)
-
(2005)
Annals of Neurology
, vol.58
, Issue.5
, pp. 730-735
-
-
Markesbery, W.R.1
Kryscio, R.J.2
Lovell, M.A.3
Morrow, J.D.4
-
11
-
-
33645106680
-
Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment
-
Wang J, Markesbery WR, Lovell MA. Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment. J Neurochem 2006;96:825-832.
-
(2006)
J Neurochem
, vol.96
, pp. 825-832
-
-
Wang, J.1
Markesbery, W.R.2
Lovell, M.A.3
-
12
-
-
13644270565
-
Oxidative DNA damage in peripheral leukocytes of mild cognitive impairment and AD patients
-
DOI 10.1016/j.neurobiolaging.2004.07.016
-
Migliore L, Fontana I, Trippi F, Colognato R, Coppede F, Tognoni G, Nucciarone B, Siciliano G. Oxidative DNA damage in peripheral leukocytes of mild cognitive impairment and AD patients. Neurobiol Aging 2005;26:567-573. (Pubitemid 40228745)
-
(2005)
Neurobiology of Aging
, vol.26
, Issue.5
, pp. 567-573
-
-
Migliore, L.1
Fontana, I.2
Trippi, F.3
Colognato, R.4
Coppede, F.5
Tognoni, G.6
Nucciarone, B.7
Siciliano, G.8
-
13
-
-
78650467580
-
Oxidative damage and progression to Alzheimer ' s disease in patients with mild cognitive impairment
-
Baldeiras I, Santana I, Proenca MT, Garrucho MH, Pascoal R, Rodrigues A, Duro D, Oliveira CR. Oxidative damage and progression to Alzheimer ' s disease in patients with mild cognitive impairment. J Alzheimers Dis 2010;21:1165-1177.
-
(2010)
J Alzheimers Dis
, vol.21
, pp. 1165-1177
-
-
Baldeiras, I.1
Santana, I.2
Proenca, M.T.3
Garrucho, M.H.4
Pascoal, R.5
Rodrigues, A.6
Duro, D.7
Oliveira, C.R.8
-
14
-
-
80053110019
-
Oxidatively modifi ed nucleic acids in preclinical Alzheimer ' s disease (PCAD) brain
-
Lovell MA, Soman S, Bradley MA. Oxidatively modifi ed nucleic acids in preclinical Alzheimer ' s disease (PCAD) brain. Mech Ageing Dev 2011;132:443-448.
-
(2011)
Mech Ageing Dev
, vol.132
, pp. 443-448
-
-
Lovell, M.A.1
Soman, S.2
Bradley, M.A.3
-
15
-
-
84855801337
-
Modest amyloid deposition is associated with iron dysregulation, microglial activation, and oxidative stress
-
doi: 10.3233/JAD-2011-110614
-
Gallagher JJ, Finnegan ME, Grehan B, Dobson J, Collingwood JF, Lynch MA. Modest amyloid deposition is associated with iron dysregulation, microglial activation, and oxidative stress. J Alzheimers Dis 2011;doi: 10.3233/JAD-2011-110614.
-
(2011)
J Alzheimers Dis
-
-
Gallagher, J.J.1
Finnegan, M.E.2
Grehan, B.3
Dobson, J.4
Collingwood, J.F.5
Lynch, M.A.6
-
17
-
-
67649687039
-
An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer ' s disease
-
Moreira PI, Duarte AI, Santos MS, Rego AC, Oliveira CR. An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer ' s disease. J Alzheimers Dis 2009;16:741-761.
-
(2009)
J Alzheimers Dis
, vol.16
, pp. 741-761
-
-
Moreira, P.I.1
Duarte, A.I.2
Santos, M.S.3
Rego, A.C.4
Oliveira, C.R.5
-
18
-
-
23844447372
-
Reactive oxygen species (ROS) and aging: Do we need them - Can we measure them - Should we block them?
-
DOI 10.1002/sita.200400053
-
Simm A, Brö m me H-J. Reactive oxygen species (ROS) and aging: do we need them-can we measure them-should we block them? Signal Transd 2005;5:115-125. (Pubitemid 41168380)
-
(2005)
Signal Transduction
, vol.5
, Issue.3
, pp. 115-125
-
-
Simm, A.1
Bromme, H.-J.2
-
19
-
-
75349112375
-
Mitochondrial turnover and aging of long-lived postmitotic cells: The mitochondrial-lysosomal axis theory of aging
-
Terman A, Kurz T, Navratil M, Arriaga EA, Brunk UT. Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging. Antioxid Redox Signal 2010;12:503-535.
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 503-535
-
-
Terman, A.1
Kurz, T.2
Navratil, M.3
Arriaga, E.A.4
Brunk, U.T.5
-
21
-
-
0028587756
-
Oxygen-derived species: Their relation to human disease and environmental stress
-
Halliwell B, Cross CE. Oxygen-derived species: their relation to human disease and environmental stress. Environ Health Perspect 1994;102(Suppl 10):5-12.
-
(1994)
Environ Health Perspect
, vol.102
, Issue.SUPPL. 10
, pp. 5-12
-
-
Halliwell, B.1
Cross, C.E.2
-
22
-
-
33749986298
-
Free radicals and antioxidants in normal physiological functions and human disease
-
DOI 10.1016/j.biocel.2006.07.001, PII S1357272506002196
-
Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007;39:44-84. (Pubitemid 44566469)
-
(2007)
International Journal of Biochemistry and Cell Biology
, vol.39
, Issue.1
, pp. 44-84
-
-
Valko, M.1
Leibfritz, D.2
Moncol, J.3
Cronin, M.T.D.4
Mazur, M.5
Telser, J.6
-
23
-
-
41149166082
-
Nucleic acid oxidation in Alzheimer disease
-
Moreira PI, Nunomura A, Nakamura M, Takeda A, Shenk JC, Aliev G, Smith MA, Perry G. Nucleic acid oxidation in Alzheimer disease. Free Radic Biol Med 2008;44: 1493-1505.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 1493-1505
-
-
Moreira, P.I.1
Nunomura, A.2
Nakamura, M.3
Takeda, A.4
Shenk, J.C.5
Aliev, G.6
Smith, M.A.7
Perry, G.8
-
24
-
-
80052538857
-
Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer ' s disease: Implications for early intervention and therapeutics
-
Mao P, Reddy PH. Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer ' s disease: implications for early intervention and therapeutics. Biochim Biophys Acta 2011;1812:1359-1370.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 1359-1370
-
-
Mao, P.1
Reddy, P.H.2
-
25
-
-
38049010515
-
Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer ' s disease
-
Lovell MA, Markesbery WR. Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer ' s disease. Nucleic Acids Res 2007;35:7497-7504.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7497-7504
-
-
Lovell, M.A.1
Markesbery, W.R.2
-
26
-
-
63349085390
-
Epigenetics, oxidative stress, and Alzheimer disease
-
Zawia NH, Lahiri DK, Cardozo-Pelaez F. Epigenetics, oxidative stress, and Alzheimer disease. Free Radic Biol Med 2009;46:1241-1249.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 1241-1249
-
-
Zawia, N.H.1
Lahiri, D.K.2
Cardozo-Pelaez, F.3
-
27
-
-
0004235430
-
-
Hoboken, NJ: John Wiley & Sons, Inc.
-
Scheffl er IE. Mitochondria. Hoboken, NJ: John Wiley & Sons, Inc.; 2008.
-
(2008)
Mitochondria
-
-
Scheffler, I.E.1
-
29
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance B, Sies H, Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol Rev 1979;59:527-605. (Pubitemid 9236599)
-
(1979)
Physiological Reviews
, vol.59
, Issue.3
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
30
-
-
71849088759
-
Mitochondria: A therapeutic target in neurodegeneration
-
Moreira PI, Zhu X, Wang X, Lee HG, Nunomura A, Petersen RB, Perry G, Smith MA. Mitochondria: a therapeutic target in neurodegeneration. Biochim Biophys Acta 2010;1802: 212-220.
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 212-220
-
-
Moreira, P.I.1
Zhu, X.2
Wang, X.3
Lee, H.G.4
Nunomura, A.5
Petersen, R.B.6
Perry, G.7
Smith, M.A.8
-
31
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy MP. How mitochondria produce reactive oxygen species. Biochem J 2009;417:1-13.
-
(2009)
Biochem J
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
32
-
-
0142150051
-
Mitochondrial formation of reactive oxygen species
-
DOI 10.1113/jphysiol.2003.049478
-
Turrens JF. Mitochondrial formation of reactive oxygen species. J Physiol 2003;552:335-344. (Pubitemid 37321833)
-
(2003)
Journal of Physiology
, vol.552
, Issue.2
, pp. 335-344
-
-
Turrens, J.F.1
-
33
-
-
0037458619
-
Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol
-
DOI 10.1074/jbc.M210269200
-
Han D, Antunes F, Canali R, Rettori D, Cadenas E. Voltagedependent anion channels control the release of the superoxide anion from mitochondria to cytosol. J Biol Chem 2003;278:5557-5563. (Pubitemid 36800797)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.8
, pp. 5557-5563
-
-
Han, D.1
Antunes, F.2
Canali, R.3
Rettori, D.4
Cadenas, E.5
-
34
-
-
10344221083
-
Complex III releases superoxide to both sides of the inner mitochondrial membrane
-
DOI 10.1074/jbc.M407715200
-
Muller FL, Liu Y, Van Remmen H. Complex III releases superoxide to both sides of the inner mitochondrial membrane. J Biol Chem 2004;279:49064-49073. (Pubitemid 39625788)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.47
, pp. 49064-49073
-
-
Muller, F.L.1
Liu, Y.2
Van Remmen, H.3
-
35
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
-
DOI 10.1146/annurev.genet.39.110304.095751
-
Wallace DC. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet 2005;39:359-407. (Pubitemid 43011120)
-
(2005)
Annual Review of Genetics
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
36
-
-
0842328003
-
Prevention of Mitochondrial Oxidative Damage As A Therapeutic Strategy in Diabetes
-
Green K, Brand MD, Murphy MP. Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes. Diabetes 2004;53(Suppl 1):S110-S118. (Pubitemid 38168702)
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 1
-
-
Green, K.1
Brand, M.D.2
Murphy, M.P.3
-
37
-
-
77956186783
-
Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes
-
Hamanaka RB, Chandel NS. Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes. Trends Biochem Sci 2010;35:505-513.
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 505-513
-
-
Hamanaka, R.B.1
Chandel, N.S.2
-
38
-
-
54049138387
-
Mechanisms of neuronal death in disease: Defi ning the models and the players
-
Ribe EM, Serrano-Saiz E, Akpan N, Troy CM. Mechanisms of neuronal death in disease: defi ning the models and the players. Biochem J 2008;415:165-182.
-
(2008)
Biochem J
, vol.415
, pp. 165-182
-
-
Ribe, E.M.1
Serrano-Saiz, E.2
Akpan, N.3
Troy, C.M.4
-
39
-
-
34249881080
-
Autophagocytosis of mitochondria is prominent in Alzheimer disease
-
DOI 10.1097/01.jnen.0000240476.73532.b0, PII 0000507220070600000007
-
Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, et al. Autophagocytosis of mitochondria is prominent in Alzheimer disease. J Neuropathol Exp Neurol 2007;66:525-532. (Pubitemid 46869694)
-
(2007)
Journal of Neuropathology and Experimental Neurology
, vol.66
, Issue.6
, pp. 525-532
-
-
Moreira, P.I.1
Siedlak, S.L.2
Wang, X.3
Santos, M.S.4
Oliveira, C.R.5
Tabaton, M.6
Nunomura, A.7
Szweda, L.I.8
Aliev, G.9
Smith, M.A.10
Zhu, X.11
Perry, G.12
-
40
-
-
77952364472
-
Decreased numeric density of succinic dehydrogenase-positive mitochondria in CA1 pyramidal neurons of 3xTg-AD mice
-
Fattoretti P, Balietti M, Casoli T, Giorgetti B, Di Stefano G, Bertoni-Freddari C, Lattanzio F, Sensi SL. Decreased numeric density of succinic dehydrogenase-positive mitochondria in CA1 pyramidal neurons of 3xTg-AD mice. Rejuvenation Res 2010;13:144-147.
-
(2010)
Rejuvenation Res
, vol.13
, pp. 144-147
-
-
Fattoretti, P.1
Balietti, M.2
Casoli, T.3
Giorgetti, B.4
Di Stefano, G.5
Bertoni-Freddari, C.6
Lattanzio, F.7
Sensi, S.L.8
-
41
-
-
69249211284
-
Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice
-
Hauptmann S, Scherping I, Drose S, Brandt U, Schulz KL, Jendrach M, et al. Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice. Neurobiol Aging 2009;30:1574-1586.
-
(2009)
Neurobiol Aging
, vol.30
, pp. 1574-1586
-
-
Hauptmann, S.1
Scherping, I.2
Drose, S.3
Brandt, U.4
Schulz, K.L.5
Jendrach, M.6
-
42
-
-
70149093436
-
Mitochondrial bioenergetic defi cit precedes Alzheimer ' s pathology in female mouse model of Alzheimer ' s disease
-
Yao J, Irwin RW, Zhao L, Nilsen J, Hamilton RT, Brinton RD. Mitochondrial bioenergetic defi cit precedes Alzheimer ' s pathology in female mouse model of Alzheimer ' s disease. Proc Nat Acad Sci USA 2009;106:14670-14675.
-
(2009)
Proc Nat Acad Sci USA
, vol.106
, pp. 14670-14675
-
-
Yao, J.1
Irwin, R.W.2
Zhao, L.3
Nilsen, J.4
Hamilton, R.T.5
Brinton, R.D.6
-
43
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
DOI 10.1038/nature05292, PII NATURE05292
-
Lin MT, Beal MF. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006;443: 787-795. (Pubitemid 44622683)
-
(2006)
Nature
, vol.443
, Issue.7113
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
44
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, et al. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol 2001;60:759-767. (Pubitemid 32678256)
-
(2001)
Journal of Neuropathology and Experimental Neurology
, vol.60
, Issue.8
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
Jones, P.K.7
Ghanbari, H.8
Wataya, T.9
Shimohama, S.10
Chiba, S.11
Atwood, C.S.12
Petersen, R.B.13
Smith, M.A.14
-
45
-
-
27544484846
-
Are mitochondria critical in the pathogenesis of Alzheimer's disease?
-
DOI 10.1016/j.brainresrev.2005.03.004, PII S0165017305000470
-
Reddy PH, Beal MF. Are mitochondria critical in the pathogenesis of Alzheimer ' s disease? Brain Res Brain Res Rev 2005;49:618-632. (Pubitemid 41546661)
-
(2005)
Brain Research Reviews
, vol.49
, Issue.3
, pp. 618-632
-
-
Reddy, P.H.1
Beal, M.F.2
-
46
-
-
71749121998
-
Mitochondrial dysfunction is a trigger of Alzheimer ' s disease pathophysiology
-
Moreira PI, Carvalho C, Zhu X, Smith MA, Perry G. Mitochondrial dysfunction is a trigger of Alzheimer ' s disease pathophysiology. Biochim Biophys Acta 2010;1802:2-10.
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 2-10
-
-
Moreira, P.I.1
Carvalho, C.2
Zhu, X.3
Smith, M.A.4
Perry, G.5
-
47
-
-
0034612075
-
A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients
-
DOI 10.1016/S0197-4580(00)00112-3, PII S0197458000001123
-
Maurer I, Zierz S, Moller HJ. A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients. Neurobiol Aging 2000;21:455-462. (Pubitemid 30349116)
-
(2000)
Neurobiology of Aging
, vol.21
, Issue.3
, pp. 455-462
-
-
Maurer, I.1
Zierz, S.2
Moller, H.-J.3
-
48
-
-
0033569839
-
Increased neuronal glucose-6-phosphate dehydrogenase and sulfhydryl levels indicate reductive compensation to oxidative stress in Alzheimer disease
-
DOI 10.1006/abbi.1999.1404
-
Russell RL, Siedlak SL, Raina AK, Bautista JM, Smith MA, Perry G. Increased neuronal glucose-6-phosphate dehydrogenase and sulfhydryl levels indicate reductive compensation to oxidative stress in Alzheimer disease. Arch Biochem Biophys 1999;370:236-239. (Pubitemid 29491430)
-
(1999)
Archives of Biochemistry and Biophysics
, vol.370
, Issue.2
, pp. 236-239
-
-
Russell, R.L.1
Siedlak, S.L.2
Raina, A.K.3
Bautista, J.M.4
Smith, M.A.5
Perry, G.6
-
49
-
-
0026408619
-
Cytochrome oxidase defi ciency in Alzheimer' s disease
-
Parker WD Jr. Cytochrome oxidase defi ciency in Alzheimer' s disease. Ann NY Acad Sci 1991;640:59-64.
-
(1991)
Ann NY Acad Sci
, vol.640
, pp. 59-64
-
-
Parker Jr., W.D.1
-
50
-
-
73949088883
-
RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction
-
T akuma K, Fang F, Zhang W, Yan S, Fukuzaki E, Du H, et al. RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction. Proc Natl Acad Sci USA 2009;106:20021-20026.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 20021-20026
-
-
Takuma, K.1
Fang, F.2
Zhang, W.3
Yan, S.4
Fukuzaki, E.5
Du, H.6
-
51
-
-
24744449326
-
Cerebrovascular damage as a cause for Alzheimer's disease
-
DOI 10.2174/156720205774322610
-
Humpel C, Marksteiner J. Cerebrovascular damage as a cause for Alzheimer ' s disease. Curr Neurovasc Res 2005;2: 341-347. (Pubitemid 41297371)
-
(2005)
Current Neurovascular Research
, vol.2
, Issue.4
, pp. 341-347
-
-
Humpel, C.1
Marksteiner, J.2
-
53
-
-
33751103136
-
Heme binding to Amyloid-β peptide: Mechanistic role in Alzheimer's disease
-
Atamna H. Heme binding to Amyloid-beta peptide: mechanistic role in Alzheimer ' s disease. J Alzheimers Dis 2006;10: 255-266. (Pubitemid 44763996)
-
(2006)
Journal of Alzheimer's Disease
, vol.10
, Issue.2-3
, pp. 255-266
-
-
Atamna, H.1
-
54
-
-
20144388830
-
ABAD enhances Aβ-induced cell stress via mitochondrial dysfunction
-
DOI 10.1096/fj.04-2582fje
-
Takuma K, Yao J, Huang J, Xu H, Chen X, Luddy J, et al. ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction. FASEB J 2005;19:597-598. (Pubitemid 40471256)
-
(2005)
FASEB Journal
, vol.19
, Issue.6
, pp. 597-598
-
-
Takuma, K.1
Yao, J.2
Huang, J.3
Xu, H.4
Chen, X.5
Luddy, J.6
Trillat, A.-C.7
Stern, D.M.8
Arancio, O.9
Yan, S.S.10
-
55
-
-
11144353586
-
ABAD Directly Links Aβ to Mitochondrial Toxicity in Alzheimer's Disease
-
DOI 10.1126/science.1091230
-
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, et al. ABAD directly links Abeta to mitochondrial toxicity in Alzheimer ' s disease. Science 2004;304:448-452. (Pubitemid 38495942)
-
(2004)
Science
, vol.304
, Issue.5669
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
Caspersen, C.7
Chen, X.8
Pollak, S.9
Chaney, M.10
Trinchese, F.11
Liu, S.12
Gunn-Moore, F.13
Lue, L.-F.14
Walker, D.G.15
Kappasamy, P.16
Zewier, Z.L.17
Arancio, O.18
Stern, D.19
Yan, S.S.D.20
Wu, H.21
more..
-
56
-
-
69949108391
-
Amyloid precursor protein, heat-shock proteins, and Bcl-2 form a complex in mitochondria and modulate mitochondria function and apoptosis in N2a cells
-
Yang TT, Hsu CT, Kuo YM. Amyloid precursor protein, heat-shock proteins, and Bcl-2 form a complex in mitochondria and modulate mitochondria function and apoptosis in N2a cells. Mech Ageing Dev 2009;130:592-601.
-
(2009)
Mech Ageing Dev
, vol.130
, pp. 592-601
-
-
Yang, T.T.1
Hsu, C.T.2
Kuo, Y.M.3
-
57
-
-
0031464288
-
Ancient mtDNA sequences in the human nuclear genome: A potential source of errors in identifying pathogenic mutations
-
DOI 10.1073/pnas.94.26.14900
-
Wallace DC, Stugard C, Murdock D, Schurr T, Brown MD. Ancient mtDNA sequences in the human nuclear genome: a potential source of errors in identifying pathogenic mutations. Proc Natl Acad Sci USA 1997;94:14900-14905. (Pubitemid 28041472)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.26
, pp. 14900-14905
-
-
Wallace, D.C.1
Stugard, C.2
Murdock, D.3
Schurr, T.4
Brown, M.D.5
-
59
-
-
58049218922
-
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fi ssion/fusion proteins
-
Wang X, Su B, Siedlak SL, Moreira PI, Fujioka H, Wang Y, Casadesus G, Zhu X. Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fi ssion/fusion proteins. Proc Natl Acad Sci USA 2008;105:19318-19323.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19318-19323
-
-
Wang, X.1
Su, B.2
Siedlak, S.L.3
Moreira, P.I.4
Fujioka, H.5
Wang, Y.6
Casadesus, G.7
Zhu, X.8
-
60
-
-
67650732998
-
Impaired balance of mitochondrial fi ssion and fusion in Alzheimer ' s disease
-
Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X. Impaired balance of mitochondrial fi ssion and fusion in Alzheimer ' s disease. J Neurosci 2009;29:9090-9103.
-
(2009)
J Neurosci
, vol.29
, pp. 9090-9103
-
-
Wang, X.1
Su, B.2
Lee, H.G.3
Li, X.4
Perry, G.5
Smith, M.A.6
Zhu, X.7
-
61
-
-
79958721260
-
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer ' s disease: Implications for neuronal damage
-
Manczak M, Calkins MJ, Reddy PH. Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer ' s disease: implications for neuronal damage. Hum Mol Genet 2011;20:2495-2509.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 2495-2509
-
-
Manczak, M.1
Calkins, M.J.2
Reddy, P.H.3
-
62
-
-
81255190781
-
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer ' s disease
-
Calkins MJ, Manczak M, Mao P, Shirendeb U, Reddy PH. Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer ' s disease. Hum Mol Genet 2011;20:4515-4529.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 4515-4529
-
-
Calkins, M.J.1
Manczak, M.2
Mao, P.3
Shirendeb, U.4
Reddy, P.H.5
-
63
-
-
84855687153
-
Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer ' s disease
-
doi: 10.1111/j.1471-4159.2011.07581.x
-
Sheng B, Wang X, Su B, Lee HG, Casadesus G, Perry G, Zhu X. Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer ' s disease. J Neurochem 2011; doi: 10.1111/j.1471-4159.2011.07581.x.
-
(2011)
J Neurochem
-
-
Sheng, B.1
Wang, X.2
Su, B.3
Lee, H.G.4
Casadesus, G.5
Perry, G.6
Zhu, X.7
-
64
-
-
79952785327
-
Metal ions Alzheimer' s disease and chelation therapy
-
Budimir A. Metal ions, Alzheimer' s disease and chelation therapy. Acta Pharm 2011;61:1-14.
-
(2011)
Acta Pharm
, vol.61
, pp. 1-14
-
-
Budimir, A.1
-
65
-
-
0347928847
-
An iron-responsive element type II in the 5′-untranslated region of the Alzheimer's amyloid precursor protein transcript
-
DOI 10.1074/jbc.M207435200
-
Rogers JT, Randall JD, Cahill CM, Eder PS, Huang X, Gunshin H, et al. An iron-responsive element type II in the 5-untranslated region of the Alzheimer ' s amyloid precursor protein transcript. J Biol Chem 2002;277:45518-45528. (Pubitemid 36159162)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.47
, pp. 45518-45528
-
-
Rogers, J.T.1
Randall, J.D.2
Cahill, C.M.3
Eder, P.S.4
Huang, X.5
Gunshin, H.6
Leiter, L.7
McPhee, J.8
Sarang, S.S.9
Utsuki, T.10
Greig, N.H.11
Lahiri, D.K.12
Tanzi, R.E.13
Bush, A.I.14
Giordano, T.15
Gullans, S.R.16
-
66
-
-
75149152568
-
Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment
-
Smith MA, Zhu X, Tabaton M, Liu G, McKeel DW Jr, Cohen ML, et al. Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J Alzheimers Dis 2010;19:363-372.
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 363-372
-
-
Smith, M.A.1
Zhu, X.2
Tabaton, M.3
Liu, G.4
McKeel Jr., D.W.5
Cohen, M.L.6
-
67
-
-
44849129360
-
Mild cognitive impairment and Alzheimer patients display different levels of redox-active CSF iron
-
Lavados M, Guillon M, Mujica MC, Rojo LE, Fuentes P, Maccioni RB. Mild cognitive impairment and Alzheimer patients display different levels of redox-active CSF iron. J Alzheimers Dis 2008;13:225-232. (Pubitemid 352038527)
-
(2008)
Journal of Alzheimer's Disease
, vol.13
, Issue.2
, pp. 225-232
-
-
Lavados, M.1
Guillon, M.2
Mujica, M.C.3
Rojo, L.E.4
Fuentes, P.5
Maccioni, R.B.6
-
68
-
-
42049116923
-
Alzheimer disease and the role of free radicals in the pathogenesis of the disease
-
DOI 10.2174/187152708783885156
-
Moreira PI, Santos MS, Oliveira CR, Shenk JC, Nunomura A, Smith MA, Zhu X, Perry G. Alzheimer disease and the role of free radicals in the pathogenesis of the disease. CNS Neurol Disord Drug Targets 2008;7:3-10. (Pubitemid 351516211)
-
(2008)
CNS and Neurological Disorders - Drug Targets
, vol.7
, Issue.1
, pp. 3-10
-
-
Moreira, P.I.1
Santos, M.S.2
Oliveira, C.R.3
Shenk, J.C.4
Nunomura, A.5
Smith, M.A.6
Zhu, X.7
Perry, G.8
-
69
-
-
1842504323
-
Redox-active metals, oxidative stress, and Alzheimer's disease pathology
-
DOI 10.1196/annals.1306.012
-
Huang X, Moir RD, Tanzi RE, Bush AI, Rogers JT. Redoxactive metals, oxidative stress, and Alzheimer ' s disease pathology. Ann N Y Acad Sci 2004;1012:153-163. (Pubitemid 38453522)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1012
, pp. 153-163
-
-
Huang, X.1
Moir, R.D.2
Tanzi, R.E.3
Bush, A.I.4
Rogers, J.T.5
-
70
-
-
79952996094
-
Iron promotes the toxicity of amyloid beta peptide by impeding its ordered aggregation
-
Liu B, Moloney A, Meehan S, Morris K, Thomas SE, Serpell LC, et al. Iron promotes the toxicity of amyloid beta peptide by impeding its ordered aggregation. J Biol Chem 2011;286:4248-4256.
-
(2011)
J Biol Chem
, vol.286
, pp. 4248-4256
-
-
Liu, B.1
Moloney, A.2
Meehan, S.3
Morris, K.4
Thomas, S.E.5
Serpell, L.C.6
-
71
-
-
79955927181
-
Aluminum, copper, iron and zinc differentially alter amyloid-Abeta(1-42) aggregation and toxicity
-
Bolognin S, Messori L, Drago D, Gabbiani C, Cendron L, Zatta P. Aluminum, copper, iron and zinc differentially alter amyloid-Abeta(1-42) aggregation and toxicity. Int J Biochem Cell Biol 2011;43:877-885.
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 877-885
-
-
Bolognin, S.1
Messori, L.2
Drago, D.3
Gabbiani, C.4
Cendron, L.5
Zatta, P.6
-
72
-
-
79953225854
-
Distinct effects of Zn2, Cu2, Fe3, and Al3on amyloid-beta stability, oligomerization, and aggregation: Amyloid-beta destabilization promotes annular protofi bril formation
-
Chen WT, Liao YH, Yu HM, Cheng IH, Chen YR. Distinct effects of Zn2, Cu2, Fe3, and Al3on amyloid-beta stability, oligomerization, and aggregation: amyloid-beta destabilization promotes annular protofi bril formation. J Biol Chem 2011;286:9646-9656.
-
(2011)
J Biol Chem
, vol.286
, pp. 9646-9656
-
-
Chen, W.T.1
Liao, Y.H.2
Yu, H.M.3
Cheng, I.H.4
Chen, Y.R.5
-
73
-
-
79954642381
-
Advances in metal-induced oxidative stress and human disease
-
Jomova K, Valko M. Advances in metal-induced oxidative stress and human disease. Toxicology 2011;283:65-87.
-
(2011)
Toxicology
, vol.283
, pp. 65-87
-
-
Jomova, K.1
Valko, M.2
-
74
-
-
0033964859
-
In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: A central role for bound transition metals
-
DOI 10.1046/j.1471-4159.2000.0740270.x
-
Sayre LM, Perry G, Harris PL, Liu Y, Schubert KA, Smith MA. In situ oxidative catalysis by neurofi brillary tangles and senile plaques in Alzheimer ' s disease: a central role for bound transition metals. J Neurochem 2000;74:270-279. (Pubitemid 30012778)
-
(2000)
Journal of Neurochemistry
, vol.74
, Issue.1
, pp. 270-279
-
-
Sayre, L.M.1
Perry, G.2
Harris, P.L.R.3
Liu, Y.4
Schubert, K.A.5
Smith, M.A.6
-
75
-
-
18344414746
-
The Aβ peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
-
DOI 10.1021/bi990438f
-
Huang X, Atwood CS, Hartshorn MA, Multhaup G, Goldstein LE, Scarpa RC, et al. The A beta peptide of Alzheimer ' s disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry (Mosc) 1999;38: 7609-7616. (Pubitemid 29289332)
-
(1999)
Biochemistry
, vol.38
, Issue.24
, pp. 7609-7616
-
-
Huang, X.1
Atwood, C.S.2
Hartshorn, M.A.3
Multhaup, G.4
Goldstein, L.E.5
Scarpa, R.C.6
Cuajungco, M.P.7
Gray, D.N.8
Lim, J.9
Moir, R.D.10
Tanzi, R.E.11
Bush, A.I.12
-
77
-
-
57449110125
-
NADPH oxidase as a therapeutic target in Alzheimer ' s disease
-
Block ML. NADPH oxidase as a therapeutic target in Alzheimer ' s disease. BMC Neurosci 2008;9(Suppl 2):S8.
-
(2008)
BMC Neurosci
, vol.9
, Issue.SUPPL. 2
-
-
Block, M.L.1
-
78
-
-
77955091304
-
Targeting NADPH oxidase and phospholipases A2 in Alzheimer ' s disease
-
Simonyi A, He Y, Sheng W, Sun AY, Wood WG, Weisman GA, Sun GY. Targeting NADPH oxidase and phospholipases A2 in Alzheimer ' s disease. Mol Neurobiol 2010;41:73-86.
-
(2010)
Mol Neurobiol
, vol.41
, pp. 73-86
-
-
Simonyi, A.1
He, Y.2
Sheng, W.3
Sun, A.Y.4
Wood, W.G.5
Weisman, G.A.6
Sun, G.Y.7
-
79
-
-
1042278903
-
NADPH oxidase
-
DOI 10.1016/j.coi.2003.12.001
-
Babior BM. NADPH oxidase. Curr Opin Immunol 2004;16:42-47. (Pubitemid 38198116)
-
(2004)
Current Opinion in Immunology
, vol.16
, Issue.1
, pp. 42-47
-
-
Babior, B.M.1
-
80
-
-
34548356689
-
Causes of oxidative stress in Alzheimer disease
-
DOI 10.1007/s00018-007-7218-4
-
Zhu X, Su B, Wang X, Smith MA, Perry G. Causes of oxidative stress in Alzheimer disease. Cell Mol Life Sci 2007;64: 2202-2210. (Pubitemid 47347959)
-
(2007)
Cellular and Molecular Life Sciences
, vol.64
, Issue.17
, pp. 2202-2210
-
-
Zhu, X.1
Su, B.2
Wang, X.3
Smith, M.A.4
Perry, G.5
-
81
-
-
67651184281
-
NOX enzymes in the central nervous system: From signaling to disease
-
Sorce S, Krause KH. NOX enzymes in the central nervous system: from signaling to disease. Antioxid Redox Signal 2009;11:2481-2504.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2481-2504
-
-
Sorce, S.1
Krause, K.H.2
-
82
-
-
0030795049
-
β-amyloid protein enhances macrophage production of oxygen free radicals and glutamate
-
DOI 10.1002/(SICI)1097-4547(19970715)49:2<229::AID-JNR11>3.0.CO;2-W
-
Klegeris A, McGeer PL. Beta-amyloid protein enhances macrophage production of oxygen free radicals and glutamate. J Neurosci Res 1997;49:229-235. (Pubitemid 27332721)
-
(1997)
Journal of Neuroscience Research
, vol.49
, Issue.2
, pp. 229-235
-
-
Klegeris, A.1
McGeer, P.L.2
-
83
-
-
45249097300
-
2 in cortical neurons
-
DOI 10.1111/j.1471-4159.2008.05347.x
-
Shelat PB, Chalimoniuk M, Wang JH, Strosznajder JB, Lee JC, Sun AY, Simonyi A, Sun GY. Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons. J Neurochem 2008;106:45-55. (Pubitemid 351840199)
-
(2008)
Journal of Neurochemistry
, vol.106
, Issue.1
, pp. 45-55
-
-
Shelat, P.B.1
Chalimoniuk, M.2
Wang, J.-H.3
Strosznajder, J.B.4
Lee, J.C.5
Sun, A.Y.6
Simonyi, A.7
Sun, G.Y.8
-
84
-
-
0029971210
-
Amyloid β protein primes cultured rat microglial cells for an enhanced phorbol 12-myristate 13-acetate-induced respiratory burst activity
-
Van Muiswinkel FL, Veerhuis R, Eikelenboom P. Amyloid beta protein primes cultured rat microglial cells for an enhanced phorbol 12-myristate 13-acetate-induced respiratory burst activity. J Neurochem 1996;66:2468-2476. (Pubitemid 26159083)
-
(1996)
Journal of Neurochemistry
, vol.66
, Issue.6
, pp. 2468-2476
-
-
Van Muiswinkel, F.L.1
Veerhuis, R.2
Eikelenboom, P.3
-
85
-
-
0034612175
-
Infl ammation and Alzheimer ' s disease
-
Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, et al. Infl ammation and Alzheimer ' s disease. Neurobiol Aging 2000;21:383-421.
-
(2000)
Neurobiol Aging
, vol.21
, pp. 383-421
-
-
Akiyama, H.1
Barger, S.2
Barnum, S.3
Bradt, B.4
Bauer, J.5
Cole, G.M.6
-
86
-
-
77951967197
-
NOX activity is increased in mild cognitive impairment
-
Bruce-Keller AJ, Gupta S, Parrino TE, Knight AG, Ebenezer PJ, Weidner AM, et al. NOX activity is increased in mild cognitive impairment. Antioxid Redox Signal 2010;12: 1371-1382.
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 1371-1382
-
-
Bruce-Keller, A.J.1
Gupta, S.2
Parrino, T.E.3
Knight, A.G.4
Ebenezer, P.J.5
Weidner, A.M.6
-
87
-
-
79957935719
-
NADPH-oxidase activation and cognition in Alzheimer disease progression
-
Ansari MA, Scheff SW. NADPH-oxidase activation and cognition in Alzheimer disease progression. Free Radic Biol Med 2011;51:171-178.
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 171-178
-
-
Ansari, M.A.1
Scheff, S.W.2
-
88
-
-
2342614850
-
Neurovascular regulation in the normal brain and in Alzheimer's disease
-
Iadecola C. Neurovascular regulation in the normal brain and in Alzheimer ' s disease. Nat Rev Neurosci 2004;5: 347-360. (Pubitemid 38568496)
-
(2004)
Nature Reviews Neuroscience
, vol.5
, Issue.5
, pp. 347-360
-
-
Iadecola, C.1
-
89
-
-
39549106246
-
Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein
-
DOI 10.1073/pnas.0711568105
-
Park L, Zhou P, Pitstick R, Capone C, Anrather J, Norris EH, et al. Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein. Proc Natl Acad Sci USA 2008;105: 1347-1352. (Pubitemid 351397056)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.4
, pp. 1347-1352
-
-
Park, L.1
Zhou, P.2
Pitstick, R.3
Capone, C.4
Anrather, J.5
Norris, E.H.6
Younkin, L.7
Younkin, S.8
Carlson, G.9
McEwen, B.S.10
Iadecola, C.11
-
90
-
-
14044258771
-
NADPH oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid β peptide
-
DOI 10.1523/JNEUROSCI.5207-04.2005
-
Park L, Anrather J, Zhou P, Frys K, Pitstick R, Younkin S, Carlson GA, Iadecola C. NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide. J Neurosci 2005;25: 1769-1777. (Pubitemid 40279282)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.7
, pp. 1769-1777
-
-
Park, L.1
Anrather, J.2
Zhou, P.3
Frys, K.4
Pitstick, R.5
Younkin, S.6
Carlson, G.A.7
Iadecola, C.8
-
91
-
-
77956207871
-
Mitochondria and antioxidant targeted therapeutic strategies for Alzheimer ' s disease
-
Dumont M, Lin MT, Beal MF. Mitochondria and antioxidant targeted therapeutic strategies for Alzheimer ' s disease. J Alzheimers Dis 2010;20(Suppl 2):S633-S643.
-
(2010)
J Alzheimers Dis
, vol.20
, Issue.SUPPL. 2
-
-
Dumont, M.1
Lin, M.T.2
Beal, M.F.3
-
92
-
-
2642544767
-
Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice
-
DOI 10.1111/j.1471-4159.2004.02455.x
-
Li F, Calingasan NY, Yu F, Mauck WM, Toidze M, Almeida CG, et al. Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice. J Neurochem 2004; 89:1308-1312. (Pubitemid 38715849)
-
(2004)
Journal of Neurochemistry
, vol.89
, Issue.5
, pp. 1308-1312
-
-
Li, F.1
Calingasan, N.Y.2
Yu, F.3
Mauck, W.M.4
Toidze, M.5
Almeida, C.G.6
Takahashi, R.H.7
Carlson, G.A.8
Beal, M.F.9
Lin, M.T.10
Gouras, G.K.11
-
93
-
-
38849150935
-
Mitochondrial oxidative stress causes hyperphosphorylation of tau
-
Melov S, Adlard PA, Morten K, Johnson F, Golden TR, Hinerfeld D, et al. Mitochondrial oxidative stress causes hyperphosphorylation of tau. PLoS ONE 2007;2:e536.
-
(2007)
PLoS ONE
, vol.2
-
-
Melov, S.1
Adlard, P.A.2
Morten, K.3
Johnson, F.4
Golden, T.R.5
Hinerfeld, D.6
-
94
-
-
33646922865
-
Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice
-
DOI 10.1523/JNEUROSCI.0482-06.2006
-
Esposito L, Raber J, Kekonius L, Yan F, Yu GQ, Bien-Ly N, et al. Reduction in mitochondrial superoxide dismutase modulates Alzheimer ' s disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice. J Neurosci 2006;26: 5167-5179. (Pubitemid 44315298)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.19
, pp. 5167-5179
-
-
Esposito, L.1
Raber, J.2
Kekonius, L.3
Yan, F.4
Yu, G.-Q.5
Bien-Ly, N.6
Puolivali, J.7
Scearce-Levie, K.8
Masliah, E.9
Mucke, L.10
-
95
-
-
68849110235
-
Reduction of oxidative stress, amyloid deposition, and memory defi cit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer ' s disease
-
Dumont M, Wille E, Stack C, Calingasan NY, Beal MF, Lin MT. Reduction of oxidative stress, amyloid deposition, and memory defi cit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer ' s disease. FASEB J 2009;23:2459-2466.
-
(2009)
FASEB J
, vol.23
, pp. 2459-2466
-
-
Dumont, M.1
Wille, E.2
Stack, C.3
Calingasan, N.Y.4
Beal, M.F.5
Lin, M.T.6
-
96
-
-
69449096141
-
Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory defi cits in a mouse model of Alzheimer ' s disease
-
Massaad CA, Washington TM, Pautler RG, Klann E. Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory defi cits in a mouse model of Alzheimer ' s disease. Proc Natl Acad Sci USA 2009;106:13576-13581.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 13576-13581
-
-
Massaad, C.A.1
Washington, T.M.2
Pautler, R.G.3
Klann, E.4
-
97
-
-
0032031780
-
Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease
-
DOI 10.1006/exnr.1997.6750
-
Marcus DL, Thomas C, Rodriguez C, Simberkoff K, Tsai JS, Strafaci JA, Freedman ML. Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer ' s disease. Exp Neurol 1998;150:40-44. (Pubitemid 28146421)
-
(1998)
Experimental Neurology
, vol.150
, Issue.1
, pp. 40-44
-
-
Marcus, D.L.1
Thomas, C.2
Rodriguez, C.3
Simberkoff, K.4
Tsai, J.S.5
Strafaci, J.A.6
Freedman, M.L.7
-
98
-
-
19444377184
-
Oxidative imbalance and cathepsin D changes as peripheral blood biomarkers of Alzheimer disease: A pilot study
-
DOI 10.1016/j.febslet.2005.03.094, PII S0014579305004655
-
Straface E, Matarrese P, Gambardella L, Vona R, Sgadari A, Silveri MC, Malorni W. Oxidative imbalance and cathepsin D changes as peripheral blood biomarkers of Alzheimer disease: a pilot study. FEBS Lett 2005;579:2759-2766. (Pubitemid 40725242)
-
(2005)
FEBS Letters
, vol.579
, Issue.13
, pp. 2759-2766
-
-
Straface, E.1
Matarrese, P.2
Gambardella, L.3
Vona, R.4
Sgadari, A.5
Silveri, M.C.6
Malorni, W.7
-
99
-
-
11844272073
-
Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice
-
DOI 10.1016/j.nbd.2004.09.003, PII S0969996104002177
-
Schuessel K, Schafer S, Bayer TA, Czech C, Pradier L, Muller-Spahn F, Muller WE, Eckert A. Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice. Neurobiol Dis 2005;18:89-99. (Pubitemid 40092899)
-
(2005)
Neurobiology of Disease
, vol.18
, Issue.1
, pp. 89-99
-
-
Schuessel, K.1
Schafer, S.2
Bayer, T.A.3
Czech, C.4
Pradier, L.5
Muller-Spahn, F.6
Muller, W.E.7
Eckert, A.8
-
100
-
-
78649820608
-
Inhibitors of catalase-amyloid interactions protect cells from beta-amyloid-induced oxidative stress and toxicity
-
Habib LK, Lee MT, Yang J. Inhibitors of catalase-amyloid interactions protect cells from beta-amyloid-induced oxidative stress and toxicity. J Biol Chem 2010;285: 38933-38943.
-
(2010)
J Biol Chem
, vol.285
, pp. 38933-38943
-
-
Habib, L.K.1
Lee, M.T.2
Yang, J.3
-
101
-
-
33646819342
-
The plasma membrane redox system in aging
-
DOI 10.1016/j.arr.2006.03.005, PII S1568163706000341
-
Hyun DH, Hernandez JO, Mattson MP, de Cabo R. The plasma membrane redox system in aging. Ageing Res Rev 2006;5:209-220. (Pubitemid 43766257)
-
(2006)
Ageing Research Reviews
, vol.5
, Issue.2
, pp. 209-220
-
-
Hyun, D.-H.1
Hernandez, J.O.2
Mattson, M.P.3
De Cabo, R.4
-
102
-
-
33846995116
-
Up-regulation of plasma membraneassociated redox activities in neuronal cells lacking functional mitochondria
-
Hyun DH, Hunt ND, Emerson SS, Hernandez JO, Mattson MP, de Cabo R. Up-regulation of plasma membraneassociated redox activities in neuronal cells lacking functional mitochondria. J Neurochem 2007;100:1364-1374.
-
(2007)
J Neurochem
, vol.100
, pp. 1364-1374
-
-
Hyun, D.H.1
Hunt, N.D.2
Emerson, S.S.3
Hernandez, J.O.4
Mattson, M.P.5
De Cabo, R.6
-
103
-
-
34248195909
-
The importance of plasma membrane coenzyme Q in aging and stress responses
-
DOI 10.1016/j.mito.2007.02.010, PII S1567724907000554, The Roled of Coenzyme Q in Cellular Metabolism: Current Biological and Clinical Aspects
-
Navas P, Villalba JM, de Cabo R. The importance of plasma membrane coenzyme Q in aging and stress responses. Mitochondrion 2007;7(Suppl):S34-40. (Pubitemid 46722290)
-
(2007)
Mitochondrion
, vol.7
, Issue.SUPPL.
-
-
Navas, P.1
Villalba, J.M.2
De Cabo, R.3
-
104
-
-
0033927296
-
Plasma membrane redox system protects cells against oxidative stress
-
Rodriguez-Aguilera JC, Lopez-Lluch G, Santos-Ocana C, Villalba JM, Gomez-Diaz C, Navas P. Plasma membrane redox system protects cells against oxidative stress. Redox Rep 2000;5:148-150.
-
(2000)
Redox Rep
, vol.5
, pp. 148-150
-
-
Rodriguez-Aguilera, J.C.1
Lopez-Lluch, G.2
Santos-Ocana, C.3
Villalba, J.M.4
Gomez-Diaz, C.5
Navas, P.6
-
105
-
-
0033920064
-
Plasma membrane redox system in the control of stress-induced apoptosis
-
Villalba JM, Navas P. Plasma membrane redox system in the control of stress-induced apoptosis. Antioxid Redox Signal 2000;2:213-230. (Pubitemid 30445934)
-
(2000)
Antioxidants and Redox Signaling
, vol.2
, Issue.2
, pp. 213-230
-
-
Villalba, J.M.1
Navas, P.2
-
106
-
-
77956430510
-
The plasma membrane redox system is impaired by amyloid beta-peptide and in the hippocampus and cerebral cortex of 3xTgAD mice
-
Hyun DH, Mughal MR, Yang H, Lee JH, Ko EJ, Hunt ND, de Cabo R, Mattson MP. The plasma membrane redox system is impaired by amyloid beta-peptide and in the hippocampus and cerebral cortex of 3xTgAD mice. Exp Neurol 2010;225:423-429.
-
(2010)
Exp Neurol
, vol.225
, pp. 423-429
-
-
Hyun, D.H.1
Mughal, M.R.2
Yang, H.3
Lee, J.H.4
Ko, E.J.5
Hunt, N.D.6
De Cabo, R.7
Mattson, M.P.8
-
107
-
-
43849096294
-
Brain oxidative stress in a tripletransgenic mouse model of Alzheimer disease
-
Resende R, Moreira PI, Proenca T, Deshpande A, Busciglio J, Pereira C, Oliveira CR. Brain oxidative stress in a tripletransgenic mouse model of Alzheimer disease. Free Radic Biol Med 2008;44:2051-2057.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 2051-2057
-
-
Resende, R.1
Moreira, P.I.2
Proenca, T.3
Deshpande, A.4
Busciglio, J.5
Pereira, C.6
Oliveira, C.R.7
-
108
-
-
70450246963
-
Depletion of vitamin e increases amyloid beta accumulation by decreasing its clearances from brain and blood in a mouse model of Alzheimer disease
-
Nishida Y, Ito S, Ohtsuki S, Yamamoto N, Takahashi T, Iwata N, et al. Depletion of vitamin E increases amyloid beta accumulation by decreasing its clearances from brain and blood in a mouse model of Alzheimer disease. J Biol Chem 2009; 284:33400-33408.
-
(2009)
J Biol Chem
, vol.284
, pp. 33400-33408
-
-
Nishida, Y.1
Ito, S.2
Ohtsuki, S.3
Yamamoto, N.4
Takahashi, T.5
Iwata, N.6
-
109
-
-
0032507983
-
Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases
-
DOI 10.1016/S0022-510X(98)00095-1, PII S0022510X98000951
-
Gu M, Owen AD, Toffa SE, Cooper JM, Dexter DT, Jenner P, Marsden CD, Schapira AH. Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases. J Neurol Sci 1998;158:24-29. (Pubitemid 28277530)
-
(1998)
Journal of the Neurological Sciences
, vol.158
, Issue.1
, pp. 24-29
-
-
Gu, M.1
Owen, A.D.2
Toffa, S.E.K.3
Cooper, J.M.4
Dexter, D.T.5
Jenner, P.6
Marsden, C.D.7
Schapira, A.H.V.8
-
110
-
-
39749157595
-
Peripheral levels of glutathione and protein oxidation as markers in the development of Alzheimer's disease from Mild Cognitive Impairment
-
DOI 10.1080/10715760701861373, PII 790807039
-
Bermejo P, Martin-Aragon S, Benedi J, Susin C, Felici E, Gil P, Ribera JM, Villar AM. Peripheral levels of glutathione and protein oxidation as markers in the development of Alzheimer ' s disease from mild cognitive impairment. Free Radic Res 2008;42:162-170. (Pubitemid 351298365)
-
(2008)
Free Radical Research
, vol.42
, Issue.2
, pp. 162-170
-
-
Bermejo, P.1
Martin-Aragon, S.2
Benedi, J.3
Susin, C.4
Felici, E.5
Gil, P.6
Ribera, J.M.7
Villar, A.Ma.8
-
111
-
-
0042591280
-
Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease
-
DOI 10.1016/S0197-4580(03)00031-9
-
Rinaldi P, Polidori MC, Metastasio A, Mariani E, Mattioli P, Cherubini A, et al. Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer ' s disease. Neurobiol Aging 2003;24:915-919. (Pubitemid 36962976)
-
(2003)
Neurobiology of Aging
, vol.24
, Issue.7
, pp. 915-919
-
-
Rinaldi, P.1
Polidori, M.C.2
Metastasio, A.3
Mariani, E.4
Mattioli, P.5
Cherubini, A.6
Catani, M.7
Cecchetti, R.8
Senin, U.9
Mecocci, P.10
-
112
-
-
0037361527
-
Glutathione cycle impairment mediates Aβ-induced cell toxicity
-
DOI 10.1080/1071576021000041023
-
Cardoso SM, Oliveira CR. Glutathione cycle impairment mediates A beta-induced cell toxicity. Free Radic Res 2003;37:241-250. (Pubitemid 36181880)
-
(2003)
Free Radical Research
, vol.37
, Issue.3
, pp. 241-250
-
-
Cardoso, S.M.1
Oliveira, C.R.2
-
113
-
-
79957456954
-
Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage
-
Svilar D, Goellner EM, Almeida KH, Sobol RW. Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage. Antioxid Redox Signal 2011;14: 2491-2507.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 2491-2507
-
-
Svilar, D.1
Goellner, E.M.2
Almeida, K.H.3
Sobol, R.W.4
-
114
-
-
0025098737
-
A cysteine-specifi c lysosomal transport system provides a major route for the delivery of thiol to human fi broblast lysosomes: Possible role in supporting lysosomal proteolysis
-
Pisoni RL, Acker TL, Lisowski KM, Lemons RM, Thoene JG. A cysteine-specifi c lysosomal transport system provides a major route for the delivery of thiol to human fi broblast lysosomes: possible role in supporting lysosomal proteolysis. J Cell Biol 1990;110:327-335.
-
(1990)
J Cell Biol
, vol.110
, pp. 327-335
-
-
Pisoni, R.L.1
Acker, T.L.2
Lisowski, K.M.3
Lemons, R.M.4
Thoene, J.G.5
-
115
-
-
0014878377
-
Histochemical indications for lysosomal localization of heavy metals in normal rat brain and liver
-
Brun A, Brunk U. Histochemical indications for lysosomal localization of heavy metals in normal rat brain and liver. J Histochem Cytochem 1970;18:820-827.
-
(1970)
J Histochem Cytochem
, vol.18
, pp. 820-827
-
-
Brun, A.1
Brunk, U.2
-
116
-
-
0035874476
-
Subcellular distribution of chelatable iron: A laser scanning microscopic study in isolated hepatocytes and liver endothelial cells
-
DOI 10.1042/0264-6021:3560061
-
Petrat F, de Groot H, Rauen U. Subcellular distribution of chelatable iron: a laser scanning microscopic study in isolated hepatocytes and liver endothelial cells. Biochem J 2001;356:61-69. (Pubitemid 34275706)
-
(2001)
Biochemical Journal
, vol.356
, Issue.1
, pp. 61-69
-
-
Petrat, F.1
De Groot, H.2
Rauen, U.3
-
117
-
-
0034656371
-
Acidic pH amplifies iron-mediated lipid peroxidation in cells
-
DOI 10.1016/S0891-5849(00)00319-1, PII S0891584900003191
-
Schafer FQ, Buettner GR. Acidic pH amplifi es ironmediated lipid peroxidation in cells. Free Radic Biol Med 2000;28:1175-1181. (Pubitemid 30417459)
-
(2000)
Free Radical Biology and Medicine
, vol.28
, Issue.8
, pp. 1175-1181
-
-
Schafer, F.Q.1
Buettner, G.R.2
-
118
-
-
18844425714
-
Role of compartmentalized redox-active iron in hydrogen peroxide-induced DNA damage and apoptosis
-
DOI 10.1042/BJ20041650
-
Tenopoulou M, Doulias PT, Barbouti A, Brunk U, Galaris D. Role of compartmentalized redox-active iron in hydrogen peroxide-induced DNA damage and apoptosis. Biochem J 2005;387:703-710. (Pubitemid 40685704)
-
(2005)
Biochemical Journal
, vol.387
, Issue.3
, pp. 703-710
-
-
Tenopoulou, M.1
Doulias, P.-T.2
Barbouti, A.3
Brunk, U.4
Galaris, D.5
-
119
-
-
1642463971
-
Relocalized redox-active lysosomal iron is an important mediator of oxidative-stress-induced DNA damage
-
DOI 10.1042/BJ20031029
-
Kurz T, Leake A, Von Zglinicki T, Brunk UT. Relocalized redox-active lysosomal iron is an important mediator of oxidative-stress-induced DNA damage. Biochem J 2004;378: 1039-1045. (Pubitemid 38406883)
-
(2004)
Biochemical Journal
, vol.378
, Issue.3
, pp. 1039-1045
-
-
Kurz, T.1
Leake, A.2
Von Zglinicki, T.3
Brunk, U.T.4
-
120
-
-
0035110055
-
Lysosomal membrane damage in soluble Aβ-mediated cell death in Alzheimer's disease
-
DOI 10.1006/nbdi.2000.0364
-
Ditaranto K, Tekirian TL, Yang AJ. Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer ' s disease. Neurobiol Dis 2001;8:19-31. (Pubitemid 32171815)
-
(2001)
Neurobiology of Disease
, vol.8
, Issue.1
, pp. 19-31
-
-
Ditaranto, K.1
Tekirian, T.L.2
Yang, A.J.3
-
121
-
-
0032526652
-
Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Aβ1-42 pathogenesis
-
DOI 10.1002/(SICI)1097-4547(19980615)52:6<691::AID-JNR8>3.0.CO;2-3
-
Yang AJ, Chandswangbhuvana D, Margol L, Glabe CG. Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Abeta1-42 pathogenesis. J Neurosci Res 1998;52:691-698. (Pubitemid 28300049)
-
(1998)
Journal of Neuroscience Research
, vol.52
, Issue.6
, pp. 691-698
-
-
Yang, A.J.1
Chandswangbhuvana, D.2
Margol, L.3
Glabe, C.G.4
-
123
-
-
56349129570
-
Formamidopyrimidines in DNA: Mechanisms of formation, repair, and biological effects
-
Dizdaroglu M, Kirkali G, Jaruga P. Formamidopyrimidines in DNA: mechanisms of formation, repair, and biological effects. Free Radic Biol Med 2008;45:1610-1621.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1610-1621
-
-
Dizdaroglu, M.1
Kirkali, G.2
Jaruga, P.3
-
124
-
-
0021769722
-
Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents
-
Kasai H, Nishimura S. Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents. Nucleic Acids Res 1984;12:2137-2145.
-
(1984)
Nucleic Acids Res
, vol.12
, pp. 2137-2145
-
-
Kasai, H.1
Nishimura, S.2
-
125
-
-
0036948404
-
Origins of spontaneous mutations: Specifi city and directionality of base-substitution, frameshift, and sequencesubstitution mutageneses
-
Maki H. Origins of spontaneous mutations: specifi city and directionality of base-substitution, frameshift, and sequencesubstitution mutageneses. Annu Rev Genet 2002;36: 279-303.
-
(2002)
Annu Rev Genet
, vol.36
, pp. 279-303
-
-
Maki, H.1
-
126
-
-
0023898319
-
Ring-opened 7-methylguanine residues in DNA are a block to in vitro DNA synthesis
-
O' C onnor TR, Boiteux S, Laval J. Ring-opened 7-methylguanine residues in DNA are a block to in vitro DNA synthesis. Nucleic Acids Res 1988;16:5879-5894.
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 5879-5894
-
-
O'Connor, T.R.1
Boiteux, S.2
Laval, J.3
-
127
-
-
0037197856
-
Antioxidant-induced changes in oxidized DNA
-
DOI 10.1073/pnas.082111199
-
Malins DC, Hellstrom KE, Anderson KM, Johnson PM, Vinson MA. Antioxidant-induced changes in oxidized DNA. Proc Natl Acad Sci USA 2002;99:5937-5941. (Pubitemid 34493243)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.9
, pp. 5937-5941
-
-
Malins, D.C.1
Hellstrom, K.E.2
Anderson, K.M.3
Johnson, P.M.4
Vinson, M.A.5
-
128
-
-
33646080824
-
Mechanisms of formation, genotoxicity, and mutation of guanine oxidation products
-
Neeley WL, Essigmann JM. Mechanisms of formation, genotoxicity, and mutation of guanine oxidation products. Chem Res Toxicol 2006;19:491-505.
-
(2006)
Chem Res Toxicol
, vol.19
, pp. 491-505
-
-
Neeley, W.L.1
Essigmann, J.M.2
-
129
-
-
7944222565
-
Recognition of the oxidized lesions spiroiminodihydantoin and guanidinohydantoin in DNA by the mammalian base excision repair glycosylases NEIL1 and NEIL2
-
DOI 10.1016/j.dnarep.2004.07.006, PII S1568786404002186
-
Hailer MK, Slade PG, Martin BD, Rosenquist TA, Sugden KD. Recognition of the oxidized lesions spiroiminodihydantoin and guanidinohydantoin in DNA by the mammalian base excision repair glycosylases NEIL1 and NEIL2. DNA Repair (Amst) 2005;4:41-50. (Pubitemid 39469081)
-
(2005)
DNA Repair
, vol.4
, Issue.1
, pp. 41-50
-
-
Hailer, M.K.1
Slade, P.G.2
Martin, B.D.3
Rosenquist, T.A.4
Sugden, K.D.5
-
130
-
-
0038799736
-
Oxidative DNA damage: Mechanisms, mutation, and disease
-
DOI 10.1096/fj.02-0752rev
-
Cooke MS, Evans MD, Dizdaroglu M, Lunec J. Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J 2003;17:1195-1214. (Pubitemid 36775767)
-
(2003)
FASEB Journal
, vol.17
, Issue.10
, pp. 1195-1214
-
-
Cooke, M.S.1
Evans, M.D.2
Dizdaroglu, M.3
Lunec, J.4
-
131
-
-
33748366270
-
Purine bases, nucleosides, and nucleotides: Aqueous solution redox chemistry and transformation reactions of their radical cations and e-and OH adducts
-
Steenken S. Purine bases, nucleosides, and nucleotides: aqueous solution redox chemistry and transformation reactions of their radical cations and e-and OH adducts. Chem Rev 1989;89:503-520.
-
(1989)
Chem Rev
, vol.89
, pp. 503-520
-
-
Steenken, S.1
-
132
-
-
27844495699
-
Base-excision repair of oxidative DNA damage by DNA glycosylases
-
DOI 10.1016/j.mrfmmm.2005.01.033, PII S0027510705002782, Mechanistic Approaches to Chemoprevention of Mutation and Cancer
-
Dizdaroglu M. Base-excision repair of oxidative DNA damage by DNA glycosylases. Mutat Res 2005;591:45-59. (Pubitemid 41654839)
-
(2005)
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
, vol.591
, Issue.1-2
, pp. 45-59
-
-
Dizdaroglu, M.1
-
133
-
-
34247156564
-
DNA repair, mitochondria, and neurodegeneration
-
DOI 10.1016/j.neuroscience.2006.08.061, PII S0306452206011730, Genome Dynamics and DNA Repair in the CNS
-
Weissman L, de Souza-Pinto NC, Stevnsner T, Bohr VA. DNA repair, mitochondria, and neurodegeneration. Neuroscience 2007;145:1318-1329. (Pubitemid 46602727)
-
(2007)
Neuroscience
, vol.145
, Issue.4
, pp. 1318-1329
-
-
Weissman, L.1
De Souza-Pinto, N.C.2
Stevnsner, T.3
Bohr, V.A.4
-
135
-
-
0042342532
-
A mechanistic perspective on the chemistry of DNA repair glycosylases
-
Stivers JT, Jiang YL. A mechanistic perspective on the chemistry of DNA repair glycosylases. Chem Rev 2003;103: 2729-2759.
-
(2003)
Chem Rev
, vol.103
, pp. 2729-2759
-
-
Stivers, J.T.1
Jiang, Y.L.2
-
136
-
-
0037112668
-
Human DNA glycosylases of the bacterial Fpg/MutM superfamily: An alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA
-
Morland I, Rolseth V, Luna L, Rognes T, Bjoras M, Seeberg E. Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA. Nucleic Acids Res 2002;30:4926-4936. (Pubitemid 35414653)
-
(2002)
Nucleic Acids Research
, vol.30
, Issue.22
, pp. 4926-4936
-
-
Morland, I.1
Rolseth, V.2
Luna, L.3
Rognes, T.4
Bjoras, M.5
Seeberg, E.6
-
137
-
-
0037133684
-
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA
-
DOI 10.1073/pnas.062053799
-
Hazra TK, Izumi T, Boldogh I, Imhoff B, Kow YW, Jaruga P, Dizdaroglu M, Mitra S. Identifi cation and characterization of a human DNA glycosylase for repair of modifi ed bases in oxidatively damaged DNA. Proc Natl Acad Sci USA 2002;99:3523-3528. (Pubitemid 34252141)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.6
, pp. 3523-3528
-
-
Hazra, T.K.1
Izumi, T.2
Boldogh, I.3
Imhoff, B.4
Kow, Y.W.5
Jaruga, P.6
Dizdaroglu, M.7
Mitra, S.8
-
138
-
-
7444266619
-
Human DNA glycosylases involved in the repair of oxidatively damaged DNA
-
DOI 10.1248/bpb.27.480
-
Ide H, Kotera M. Human DNA glycosylases involved in the repair of oxidatively damaged DNA. Biol Pharm Bull 2004;27:480-485. (Pubitemid 41701830)
-
(2004)
Biological and Pharmaceutical Bulletin
, vol.27
, Issue.4
, pp. 480-485
-
-
Ide, H.1
Kotera, M.2
-
139
-
-
0033539610
-
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
-
Klungland A, Rosewell I, Hollenbach S, Larsen E, Daly G, Epe B, et al. Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc Natl Acad Sci USA 1999;96:13300-13305.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13300-13305
-
-
Klungland, A.1
Rosewell, I.2
Hollenbach, S.3
Larsen, E.4
Daly, G.5
Epe, B.6
-
140
-
-
0035878869
-
Repair of 8-oxodeoxyguanosine lesions in mitochondrial DNA depends on the oxoguanine DNA glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial DNA of OGG1-defective mice
-
de Souza-Pinto NC, Eide L, Hogue BA, Thybo T, Stevnsner T, Seeberg E, Klungland A, Bohr VA. Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice. Cancer Res 2001;61:5378-5381. (Pubitemid 32694914)
-
(2001)
Cancer Research
, vol.61
, Issue.14
, pp. 5378-5381
-
-
De Souza-Pinto, N.C.1
Eide, L.2
Hogue, B.A.3
Thybo, T.4
Stevnsner, T.5
Seeberg, E.6
Klungland, A.7
Bohr, V.A.8
-
141
-
-
27844501168
-
Molecular and biological roles of Ape1 protein in mammalian base excision repair
-
DOI 10.1016/j.dnarep.2005.09.004, PII S1568786405002557
-
Demple B, Sung JS. Molecular and biological roles of Ape1 protein in mammalian base excision repair. DNA Repair (Amst) 2005;4:1442-1449. (Pubitemid 41653305)
-
(2005)
DNA Repair
, vol.4
, Issue.12
, pp. 1442-1449
-
-
Demple, B.1
Sung, J.-S.2
-
142
-
-
0035837587
-
The major human abasic endonuclease: Formation, consequences and repair of abasic lesions in DNA
-
DOI 10.1016/S0921-8777(01)00063-5, PII S0921877701000635
-
Wilson DM 3rd, Barsky D. The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA. Mutat Res 2001;485:283-307. (Pubitemid 32406284)
-
(2001)
Mutation Research - DNA Repair
, vol.485
, Issue.4
, pp. 283-307
-
-
Wilson III, D.M.1
Barsky, D.2
-
143
-
-
0036570012
-
Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells
-
DOI 10.1016/S0891-5849(02)00787-6, PII S0891584902007876
-
Bohr VA. Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells. Free Radic Biol Med 2002;32:804-812. (Pubitemid 34439251)
-
(2002)
Free Radical Biology and Medicine
, vol.32
, Issue.9
, pp. 804-812
-
-
Bohr, V.A.1
-
144
-
-
0019423856
-
Sequence and organization of the human mitochondrial genome
-
DOI 10.1038/290457a0
-
Anderson S, Bankier AT, Barrell BG, de Bruijn MH, Coulson AR, Drouin J, et al. Sequence and organization of the human mitochondrial genome. Nature 1981;290:457-465. (Pubitemid 11159074)
-
(1981)
Nature
, vol.290
, Issue.5806
, pp. 457-465
-
-
Anderson, S.1
Bankier, A.T.2
Barrell, B.G.3
-
145
-
-
65349123514
-
Mitochondrial reactive oxygen species production in excitable cells: Modulators of mitochondrial and cell function
-
Stowe DF, Camara AK. Mitochondrial reactive oxygen species production in excitable cells: modulators of mitochondrial and cell function. Antioxid Redox Signal 2009;11: 1373-1414.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 1373-1414
-
-
Stowe, D.F.1
Camara, A.K.2
-
147
-
-
0030841051
-
Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene
-
DOI 10.1093/nar/25.4.750
-
Nilsen H, Otterlei M, Haug T, Solum K, Nagelhus TA, Skorpen F, Krokan HE. Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene. Nucleic Acids Res 1997;25:750-755. (Pubitemid 27299828)
-
(1997)
Nucleic Acids Research
, vol.25
, Issue.4
, pp. 750-755
-
-
Nilsen, H.1
Otterlei, M.2
Haug, T.3
Solum, K.4
Nagelhus, T.A.5
Skorpen, F.6
Krokan, H.E.7
-
148
-
-
0032945268
-
Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs
-
Nishioka K, Ohtsubo T, Oda H, Fujiwara T, Kang D, Sugimachi K, Nakabeppu Y. Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs. Mol Biol Cell 1999;10:1637-1652. (Pubitemid 29230914)
-
(1999)
Molecular Biology of the Cell
, vol.10
, Issue.5
, pp. 1637-1652
-
-
Nishioka, K.1
Ohtsubo, T.2
Oda, H.3
Fujiwara, T.4
Kang, D.5
Sugimachi, K.6
Nakabeppu, Y.7
-
149
-
-
28844478775
-
Repair of formamidopyrimidines in DNA involves different glycosylases: Role of the OGG1, NTH1, and NEIL1 enzymes
-
DOI 10.1074/jbc.M508772200
-
Hu J, de Souza-Pinto NC, Haraguchi K, Hogue BA, Jaruga P, Greenberg MM, Dizdaroglu M, Bohr VA. Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes. J Biol Chem 2005;280:40544-40551. (Pubitemid 41780543)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.49
, pp. 40544-40551
-
-
Hu, J.1
De Souza-Pinto, N.C.2
Haraguchi, K.3
Hogue, B.A.4
Jaruga, P.5
Greenberg, M.M.6
Dizdaroglu, M.7
Bohr, V.A.8
-
150
-
-
0031984582
-
Asbestos increases mammalian AP-endonuclease gene expression, protein levels, and enzyme activity in mesothelial cells
-
Fung H, Kow YW, Van Houten B, Taatjes DJ, Hatahet Z, Janssen YM, et al. Asbestos increases mammalian APendonuclease gene expression, protein levels, and enzyme activity in mesothelial cells. Cancer Res 1998;58:189-194. (Pubitemid 28047051)
-
(1998)
Cancer Research
, vol.58
, Issue.2
, pp. 189-194
-
-
Fung, H.1
Kow, Y.W.2
Van Houten, B.3
Taatjes, D.J.4
Hatahet, Z.5
Janssen, Y.M.W.6
Vacek, P.7
Faux, S.P.8
Mossman, B.T.9
-
151
-
-
0028007266
-
Expression of a multifunctional DNA repair enzyme gene, apurinic/apyrimidinic endonuclease (APE; Ref-1) in the suprachiasmatic, supraoptic and paraventricular nuclei
-
DOI 10.1016/0006-8993(94)90296-8
-
Rivkees SA, Kelley MR. Expression of a multifunctional DNA repair enzyme gene, apurinic/apyrimidinic endonuclease (APE; Ref-1) in the suprachiasmatic, supraoptic and paraventricular nuclei. Brain Res 1994;666:137-142. (Pubitemid 24359666)
-
(1994)
Brain Research
, vol.666
, Issue.1
, pp. 137-142
-
-
Rivkees, S.A.1
Kelley, M.R.2
-
152
-
-
0030004546
-
Differential expression of the apurinic/apyrimidinic endonuclease (APE/ref-1) multifunctional DNA base excision repair gene during fetal development and in adult rat brain and testis
-
DOI 10.1016/0921-8777(95)00053-4
-
Wilson TM, Rivkees SA, Deutsch WA, Kelley MR. Differential expression of the apurinic/apyrimidinic endonuclease (APE/ref-1) multifunctional DNA base excision repair gene during fetal development and in adult rat brain and testis. Mutat Res 1996;362:237-248. (Pubitemid 26102977)
-
(1996)
Mutation Research - DNA Repair
, vol.362
, Issue.3
, pp. 237-248
-
-
Wilson, T.M.1
Rivkees, S.A.2
Deutsch, W.A.3
Kelley, M.R.4
-
153
-
-
0034667766
-
Mitochondrial DNA ligase III function is independent of Xrcc1
-
Lakshmipathy U, Campbell C. Mitochondrial DNA ligase III function is independent of Xrcc1. Nucleic Acids Res 2000;28:3880-3886.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 3880-3886
-
-
Lakshmipathy, U.1
Campbell, C.2
-
154
-
-
0032960864
-
The human DNA ligase III gene encodes nuclear and mitochondrial proteins
-
Lakshmipathy U, Campbell C. The human DNA ligase III gene encodes nuclear and mitochondrial proteins. Mol Cell Biol 1999;19:3869-3876. (Pubitemid 29193846)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.5
, pp. 3869-3876
-
-
Lakshmipathy, U.1
Campbell, C.2
-
155
-
-
29244433031
-
Mitochondrial DNA integrity is not dependent on DNA polymerase-β activity
-
DOI 10.1016/j.dnarep.2005.07.009, PII S1568786405002004
-
Hansen AB, Griner NB, Anderson JP, Kujoth GC, Prolla TA, Loeb LA, Glick E. Mitochondrial DNA integrity is not dependent on DNA polymerase-beta activity. DNA Repair (Amst) 2006;5:71-79. (Pubitemid 41832513)
-
(2006)
DNA Repair
, vol.5
, Issue.1
, pp. 71-79
-
-
Hansen, A.B.1
Griner, N.B.2
Anderson, J.P.3
Kujoth, G.C.4
Prolla, T.A.5
Loeb, L.A.6
Glick, E.7
-
156
-
-
2342429459
-
DNA polymerase γ, the mitochondrial replicase
-
DOI 10.1146/annurev.biochem.72.121801.161455
-
Kaguni LS. DNA polymerase gamma, the mitochondrial replicase. Annu Rev Biochem 2004;73:293-320. (Pubitemid 39050371)
-
(2004)
Annual Review of Biochemistry
, vol.73
, pp. 293-320
-
-
Kaguni, L.S.1
-
157
-
-
0036118571
-
Base excision repair is limited by different proteins in male germ cell nuclear extracts prepared from young and old mice
-
DOI 10.1128/MCB.22.7.2410-2418.2002
-
Intano GW, McMahan CA, McCarrey JR, Walter RB, McKenna AE, Matsumoto Y, et al. Base excision repair is limited by different proteins in male germ cell
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.7
, pp. 2410-2418
-
-
Intano, G.W.1
McMahan, C.A.2
McCarrey, J.R.3
Walter, R.B.4
McKenna, A.E.5
Matsumoto, Y.6
MacInnes, M.A.7
Chen, D.J.8
Walter, C.A.9
-
158
-
-
0037341775
-
Age-related base excision repair activity in mouse brain and liver nuclear extracts
-
Intano GW, Cho EJ, McMahan CA, Walter CA. Age-related base excision repair activity in mouse brain and liver nuclear extracts. J Gerontol A Biol Sci Med Sci 2003;58:205-211. (Pubitemid 36307590)
-
(2003)
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
, vol.58
, Issue.3
, pp. 205-211
-
-
Intano, G.W.1
Cho, E.J.2
McMahan, C.A.3
Walter, C.A.4
-
159
-
-
33744912521
-
Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an age-dependent manner
-
DOI 10.1016/j.neurobiolaging.2005.06.002, PII S0197458005001739
-
Imam SZ, Karahalil B, Hogue BA, Souza-Pinto NC, Bohr VA. Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an agedependent manner. Neurobiol Aging 2006;27:1129-1136. (Pubitemid 43850641)
-
(2006)
Neurobiology of Aging
, vol.27
, Issue.8
, pp. 1129-1136
-
-
Imam, S.Z.1
Karahalil, B.2
Hogue, B.A.3
Souza-Pinto, N.C.4
Bohr, V.A.5
-
160
-
-
0036316413
-
Age-dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria
-
DOI 10.1046/j.1471-4159.2002.00916.x
-
Chen D, Cao G, Hastings T, Feng Y, Pei W, O' H oro C, Chen J. Age-dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria. J Neurochem 2002;81: 1273-1284. (Pubitemid 34809261)
-
(2002)
Journal of Neurochemistry
, vol.81
, Issue.6
, pp. 1273-1284
-
-
Chen, D.1
Cao, G.2
Hastings, T.3
Feng, Y.4
Pei, W.5
O'Horo, C.6
Chen, J.7
-
161
-
-
8344257204
-
Age-dependent modulation of DNA repair enzymes by covalent modification and subcellular distribution
-
DOI 10.1016/j.mad.2004.07.005, PII S0047637404001666
-
Szczesny B, Bhakat KK, Mitra S, Boldogh I. Age-dependent modulation of DNA repair enzymes by covalent modifi cation and subcellular distribution. Mech Ageing Dev 2004;125:755-765. (Pubitemid 39482404)
-
(2004)
Mechanisms of Ageing and Development
, vol.125
, Issue.SPEC. ISS.
, pp. 755-765
-
-
Szczesny, B.1
Bhakat, K.K.2
Mitra, S.3
Boldogh, I.4
-
162
-
-
77956545422
-
Specifi c Inhibition of NEIL-initiated repair of oxidized base damage in human genome by copper and iron: Potential etiological linkage to neurodegenerative diseases
-
Hegde ML, Hegde PM, Holthauzen LM, Hazra TK, Rao KS, Mitra S. Specifi c Inhibition of NEIL-initiated repair of oxidized base damage in human genome by copper and iron: potential etiological linkage to neurodegenerative diseases. J Biol Chem 2010;285:28812-28825.
-
(2010)
J Biol Chem
, vol.285
, pp. 28812-28825
-
-
Hegde, M.L.1
Hegde, P.M.2
Holthauzen, L.M.3
Hazra, T.K.4
Rao, K.S.5
Mitra, S.6
-
163
-
-
33646945579
-
Age-related loss of the DNA repair response following exposure to oxidative stress
-
Cabelof DC, Raffoul JJ, Ge Y, Van Remmen H, Matherly LH, Heydari AR. Age-related loss of the DNA repair response following exposure to oxidative stress. J Gerontol A Biol Sci Med Sci 2006;61:427-434. (Pubitemid 43794700)
-
(2006)
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
, vol.61
, Issue.5
, pp. 427-434
-
-
Cabelof, D.C.1
Raffoul, J.J.2
Ge, Y.3
Van Remmen, H.4
Matherly, L.H.5
Heydari, A.R.6
-
164
-
-
0141480060
-
Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases
-
DOI 10.1073/pnas.1932854100
-
Szczesny B, Hazra TK, Papaconstantinou J, Mitra S, Boldogh I. Age-dependent defi ciency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases. Proc Natl Acad Sci USA 2003;100: 10670-10675. (Pubitemid 37140086)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.19
, pp. 10670-10675
-
-
Szczesny, B.1
Hazra, T.K.2
Papaconstantinou, J.3
Mitra, S.4
Boldogh, I.5
-
165
-
-
58649099395
-
Age-associated oxidative damage to the p62 promoter: Implications for Alzheimer disease
-
Du Y, Wooten MC, Gearing M, Wooten MW. Age-associated oxidative damage to the p62 promoter: implications for Alzheimer disease. Free Radic Biol Med 2009;46:492-501.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 492-501
-
-
Du, Y.1
Wooten, M.C.2
Gearing, M.3
Wooten, M.W.4
-
166
-
-
2442585133
-
Transcriptional activation of p62/A170/ZIP during the formation of the aggregates: Possible mechanisms and the role in Lewy body formation in Parkinson's disease
-
DOI 10.1016/j.brainres.2004.03.029, PII S0006899304004743
-
Nakaso K, Yoshimoto Y, Nakano T, Takeshima T, Fukuhara Y, Yasui K, et al. Transcriptional activation of p62/A170/ZIP during the formation of the aggregates: possible mechanisms and the role in Lewy body formation in Parkinson ' s disease. Brain Res 2004;1012:42-51. (Pubitemid 38648897)
-
(2004)
Brain Research
, vol.1012
, Issue.1-2
, pp. 42-51
-
-
Nakaso, K.1
Yoshimoto, Y.2
Nakano, T.3
Takeshima, T.4
Fukuhara, Y.5
Yasui, K.6
Araga, S.7
Yanagawa, T.8
Ishii, T.9
Nakashima, K.10
-
167
-
-
45249105920
-
Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration
-
DOI 10.1111/j.1471-4159.2008.05340.x
-
Ramesh Babu J, Lamar Seibenhener M, Peng J, Strom AL, Kemppainen R, Cox N, et al. Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration. J Neurochem 2008;106:107-120. (Pubitemid 351840194)
-
(2008)
Journal of Neurochemistry
, vol.106
, Issue.1
, pp. 107-120
-
-
Ramesh Babu, J.1
Lamar Seibenhener, M.2
Peng, J.3
Strom, A.-L.4
Kemppainen, R.5
Cox, N.6
Zhu, H.7
Wooten, M.C.8
Diaz-Meco, M.T.9
Moscat, J.10
Wooten, M.W.11
-
168
-
-
34548802393
-
Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment
-
DOI 10.1093/nar/gkm605
-
Weissman L, Jo DG, Sorensen MM, de Souza-Pinto NC, Markesbery WR, Mattson MP, Bohr VA. Defective DNA base excision repair in brain from individuals with Alzheimer ' s disease and amnestic mild cognitive impairment. Nucleic Acids Res 2007;35:5545-5555. (Pubitemid 47423927)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.16
, pp. 5545-5555
-
-
Weissman, L.1
Jo, D.-G.2
Sorensen, M.M.3
De Souza-Pinto, N.C.4
Markesbery, W.R.5
Mattson, M.P.6
Bohr, V.A.7
-
169
-
-
79960452243
-
Expression of 8-oxoguanine DNA glycosylase 1 (OGG1) and the level of p53 and TNFalphalpha proteins in peripheral lymphocytes of patients with Alzheimer ' s disease
-
Dezor M, Dorszewska J, Florczak J, Kempisty B, Jaroszewska-Kolecka J, Rozycka A, et al. Expression of 8-oxoguanine DNA glycosylase 1 (OGG1) and the level of p53 and TNFalphalpha proteins in peripheral lymphocytes of patients with Alzheimer ' s disease. Folia Neuropathol 2011;49: 123-131.
-
(2011)
Folia Neuropathol
, vol.49
, pp. 123-131
-
-
Dezor, M.1
Dorszewska, J.2
Florczak, J.3
Kempisty, B.4
Jaroszewska-Kolecka, J.5
Rozycka, A.6
-
170
-
-
54949146482
-
Altered 8-oxoguanine glycosylase in mild cognitive impairment and late-stage Alzheimer ' s disease brain
-
Shao C, Xiong S, Li GM, Gu L, Mao G, Markesbery WR, Lovell MA. Altered 8-oxoguanine glycosylase in mild cognitive impairment and late-stage Alzheimer ' s disease brain. Free Radic Biol Med 2008;45:813-819.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 813-819
-
-
Shao, C.1
Xiong, S.2
Li, G.M.3
Gu, L.4
Mao, G.5
Markesbery, W.R.6
Lovell, M.A.7
-
172
-
-
79551536942
-
Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer ' s disease
-
doi:10.1016/j.neurobiolaging.2010. 1006.1019
-
Gredilla R, Weissman L, Yang JL, Bohr VA, Stevnsner T. Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer ' s disease. Neurobiol Aging 2010; doi:10.1016/j.neurobiolaging.2010. 1006.1019.
-
(2010)
Neurobiol Aging
-
-
Gredilla, R.1
Weissman, L.2
Yang, J.L.3
Bohr, V.A.4
Stevnsner, T.5
-
173
-
-
4544225426
-
Detection of oxidative DNA damage in lymphocytes of patients with Alzheimer's disease
-
DOI 10.1080/13547500410001728390
-
Kadioglu E, Sardas S, Aslan S, Isik E, Esat Karakaya A. Detection of oxidative DNA damage in lymphocytes of patients with Alzheimer ' s disease. Biomarkers 2004;9: 203-209. (Pubitemid 39255641)
-
(2004)
Biomarkers
, vol.9
, Issue.2
, pp. 203-209
-
-
Kadioglu, E.1
Sardas, S.2
Aslan, S.3
Isik, E.4
Karakaya, A.E.5
-
174
-
-
0031687672
-
Oxidative damage to DNA in lymphocytes from AD patients
-
Mecocci P, Polidori MC, Ingegni T, Cherubini A, Chionne F, Cecchetti R, Senin U. Oxidative damage to DNA in lymphocytes from AD patients. Neurology 1998;51: 1014-1017. (Pubitemid 28473393)
-
(1998)
Neurology
, vol.51
, Issue.4
, pp. 1014-1017
-
-
Mecocci, P.1
Polidori, M.C.2
Ingegni, T.3
Cherubini, A.4
Chionne, F.5
Cecchetti, R.6
Senin, U.7
-
175
-
-
0036141861
-
Elevated levels of oxidative DNA damage in lymphocytes from patients with Alzheimer's disease
-
DOI 10.1016/S0197-4580(01)00257-3, PII S0197458001002573
-
Morocz M, Kalman J, Juhasz A, Sinko I, McGlynn AP, Downes CS, Janka Z, Rasko I. Elevated levels of oxidative DNA damage in lymphocytes from patients with Alzheimer ' s disease. Neurobiol Aging 2002;23:47-53. (Pubitemid 34070637)
-
(2002)
Neurobiology of Aging
, vol.23
, Issue.1
, pp. 47-53
-
-
Morocz, M.1
Kalman, J.2
Juhasz, A.3
Sinko, I.4
McGlynn, A.P.5
Downes C.Stephen6
Janka, Z.7
Rasko, I.8
-
176
-
-
0032933750
-
Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF
-
DOI 10.1046/j.1471-4159.1999.0720771.x
-
Lovell MA, Gabbita SP, Markesbery WR. Increased DNA oxidation and decreased levels of repair products in Alzheimer ' s disease ventricular CSF. J Neurochem 1999;72: 771-776. (Pubitemid 29055242)
-
(1999)
Journal of Neurochemistry
, vol.72
, Issue.2
, pp. 771-776
-
-
Lovell, M.A.1
Gabbita, S.P.2
Markesbery, W.R.3
-
177
-
-
18844462415
-
Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease
-
DOI 10.1111/j.1471-4159.2005.03053.x
-
Wang J, Xiong S, Xie C, Markesbery WR, Lovell MA. Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer ' s disease. J Neurochem 2005;93:953-962. (Pubitemid 40695754)
-
(2005)
Journal of Neurochemistry
, vol.93
, Issue.4
, pp. 953-962
-
-
Wang, J.1
Xiong, S.2
Xie, C.3
Markesbery, W.R.4
Lovell, M.A.5
-
178
-
-
42749087763
-
The mitochondrial impairment oxidative stress and neurodegeneration connection: Reality or just an attractive hypothesis?
-
Fukui H, Moraes CT. The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis? Trends Neurosci 2008;31: 251-256.
-
(2008)
Trends Neurosci
, vol.31
, pp. 251-256
-
-
Fukui, H.1
Moraes, C.T.2
-
179
-
-
34250656608
-
Mitochondria and neurodegeneration
-
DOI 10.1007/s10540-007-9038-z
-
Petrozzi L, Ricci G, Giglioli NJ, Siciliano G, Mancuso M. Mitochondria and neurodegeneration. Biosci Rep 2007;27: 87-104. (Pubitemid 46940938)
-
(2007)
Bioscience Reports
, vol.27
, Issue.1-3
, pp. 87-104
-
-
Petrozzi, L.1
Ricci, G.2
Giglioli, N.J.3
Siciliano, G.4
Mancuso, M.5
|