Amyloid precursor protein, heat-shock proteins, and Bcl-2 form a complex in mitochondria and modulate mitochondria function and apoptosis in N2a cells

Mechanisms of Ageing and Development

Volumn 130, Issue 9, 2009, Pages 592-601

  Yang, Ting Ting ^a   Hsu, Chao Tien ^b   Kuo, Yu Min ^c  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b I SHOU UNIVERSITY   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Apoptosis; Bcl 2; Heat shock proteins; Mitochondria

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CALCIUM; CHAPERONE; CYTOCHROME C OXIDASE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 30; HEAT SHOCK PROTEIN 32; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN BLOOD FLOW; COMPLEX FORMATION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FLOW CYTOMETRY; GENE OVEREXPRESSION; HYPOTHESIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NERVE CELL DEGENERATION; NEUROBLASTOMA CELL; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TRANSPORT;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CULTURE MEDIA, SERUM-FREE; HEAT-SHOCK PROTEINS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; MODELS, BIOLOGICAL; NEUROBLASTOMA; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSFECTION;

EID: 69949108391     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2009.07.002     Document Type: Article

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