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Volumn 30, Issue SUPPL.2, 2012, Pages

Dyslipidemia and dementia: Current epidemiology, genetic evidence, and mechanisms behind the associations

Author keywords

Alzheimer's disease; amyloid; amyloid peptides; amyloid protein precursor; cholesterol; genetics; neurodegeneration

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER A2; ABC TRANSPORTER G1; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; AMYLOID PROTEIN; APOLIPOPROTEIN A1; APOLIPOPROTEIN C1; APOLIPOPROTEIN C2; APOLIPOPROTEIN C3; APOLIPOPROTEIN E; BETA SECRETASE; CAVEOLIN 1; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEIN; CLUSTERIN; GAMMA SECRETASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE (NADPH); HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MEMBRANE LIPID; SORTILIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TAU PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN RECEPTOR;

EID: 84863006444     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2011-110599     Document Type: Review
Times cited : (52)

References (178)
  • 1
    • 0031695197 scopus 로고    scopus 로고
    • Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset
    • Brookmeyer R, Gray S, Kawas C (1998) Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. Am J Public Health 88, 1337-1342. (Pubitemid 28402270)
    • (1998) American Journal of Public Health , vol.88 , Issue.9 , pp. 1337-1342
    • Brookmeyer, R.1    Gray, S.2    Kawas, C.3
  • 2
    • 0032916242 scopus 로고    scopus 로고
    • Aging and the occurrence of dementia: Findings from a population-based cohort with a large sample of nonagenarians
    • DOI 10.1001/archneur.56.5.587
    • von Strauss E, Viitanen M, De Ronchi D, Winblad B, Fratiglioni L (1999) Aging and the occurrence of dementia: Findings from a population-based cohort with a large sample of nonagenarians. Arch Neurol 56, 587-592. (Pubitemid 29218154)
    • (1999) Archives of Neurology , vol.56 , Issue.5 , pp. 587-592
    • Von Strauss, E.1    Viitanen, M.2    De Ronchi, D.3    Winblad, B.4    Fratiglioni, L.5
  • 8
    • 11844285607 scopus 로고    scopus 로고
    • Cholesterol, transferrin saturation, and the development of dementia and Alzheimer's disease: Results from an 18-year population-based cohort
    • Mainous AG, 3rd, Eschenbach SL, Wells BJ, Everett CJ, Gill JM (2005) Cholesterol, transferrin saturation, and the development of dementia and Alzheimer's disease: Results from an 18-year population-based cohort. Fam Med 37, 36-42. (Pubitemid 40094090)
    • (2005) Family Medicine , vol.37 , Issue.1 , pp. 36-42
    • Mainous III, A.G.1    Eschenbach, S.L.2    Wells, B.J.3    Everett, C.J.4    Gill, J.M.5
  • 9
    • 0033546660 scopus 로고    scopus 로고
    • APOE genotype, plasma lipids, lipoproteins, and AD in community elderly
    • Romas SN, Tang MX, Berglund L, Mayeux R (1999) APOE genotype, plasma lipids, lipoproteins, andADin community elderly. Neurology 53, 517-521. (Pubitemid 29382044)
    • (1999) Neurology , vol.53 , Issue.3 , pp. 517-521
    • Romas, S.N.1    Tang, M.-X.2    Berglund, L.3    Mayeux, R.4
  • 12
    • 12744273863 scopus 로고    scopus 로고
    • Midlife cardiovascular risk factors andriskofdemen-tia in late life
    • Whitmer RA, Sidney S, Selby J, Johnston SC, Yaffe K (2005) Midlife cardiovascular risk factors andriskofdemen-tia in late life. Neurology 64, 277-281.
    • (2005) Neurology , vol.64 , pp. 277-281
    • Whitmer, R.A.1    Sidney, S.2    Selby, J.3    Johnston, S.C.4    Yaffe, K.5
  • 13
    • 18844457544 scopus 로고    scopus 로고
    • High total cholesterol levels in late life associated with a reduced risk of dementia
    • DOI 10.1212/01.WNL.0000161870.78572.A5
    • Mielke MM, Zandi PP, Sjogren M, Gustafson D, Ostling S, Steen B, Skoog I (2005) High total cholesterol levels in late life associated with a reduced risk of dementia. Neurology 64, 1689-1695. (Pubitemid 40695799)
    • (2005) Neurology , vol.64 , Issue.10 , pp. 1689-1695
    • Mielke, M.M.1    Zandi, P.P.2    Sjogren, M.3    Gustafson, D.4    Ostling, S.5    Steen, B.6    Skoog, I.7
  • 14
    • 2442489033 scopus 로고    scopus 로고
    • Relation of plasma lipids to alzheimer disease and vascular dementia
    • DOI 10.1001/archneur.61.5.705
    • Reitz C, Tang MX, Luchsinger J, Mayeux R (2004) Relation of plasma lipidstoAlzheimer disease andvascular dementia. Arch Neurol 61, 705-714. (Pubitemid 38637688)
    • (2004) Archives of Neurology , vol.61 , Issue.5 , pp. 705-714
    • Reitz, C.1    Tang, M.-X.2    Luchsinger, J.3    Mayeux, R.4
  • 16
    • 33846061128 scopus 로고    scopus 로고
    • Twenty-six-year change in total cholesterol levels and incident dementia: The Honolulu-Asia aging study
    • DOI 10.1001/archneur.64.1.103
    • Stewart R, White LR, Xue QL, Launer LJ (2007) Twenty-six-year change in total cholesterol levels and incident dementia: The Honolulu-Asia Aging Study. Arch Neurol64, 103-107. (Pubitemid 46072431)
    • (2007) Archives of Neurology , vol.64 , Issue.1 , pp. 103-107
    • Stewart, R.1    White, L.R.2    Xue, Q.-L.3    Launer, L.J.4
  • 18
    • 74049129773 scopus 로고    scopus 로고
    • Serum HDL, LDL and total cholesterol in patients with late-life onset of Alzheimer's disease versus vascular dementia
    • Trkanjec Z, Bene R, Martinic-Popovic I, Jurasic JM, Lisak M, Seric V, Demarin V (2009) Serum HDL, LDL and total cholesterol in patients with late-life onset of Alzheimer's disease versus vascular dementia. Acta Clin Croat 48, 259-263.
    • (2009) Acta Clin Croat , vol.48 , pp. 259-263
    • Trkanjec, Z.1    Bene, R.2    Martinic-Popovic, I.3    Jurasic, J.M.4    Lisak, M.5    Seric, V.6    Demarin, V.7
  • 19
    • 78650094288 scopus 로고    scopus 로고
    • Association of higher levels of high-density lipoprotein cholesterol in elderly individuals and lower risk of late-onset Alzheimer disease
    • Reitz C, Tang MX, Schupf N, Manly JJ, Mayeux R, Luchsinger JA (2010) Association of higher levels of high-density lipoprotein cholesterol in elderly individuals and lower risk of late-onset Alzheimer disease. Arch Neurol 67, 1491-1497.
    • (2010) Arch Neurol , vol.67 , pp. 1491-1497
    • Reitz, C.1    Tang, M.X.2    Schupf, N.3    Manly, J.J.4    Mayeux, R.5    Luchsinger, J.A.6
  • 24
    • 0037445920 scopus 로고    scopus 로고
    • Cholesterol paradox: Is high total or low HDL cholesterol level a risk for Alzheimer's disease?
    • DOI 10.1002/jnr.10585
    • Michikawa M (2003) Cholesterol paradox: Is high total or low HDL cholesterol level a risk for Alzheimer's disease? J Neurosci Res 72, 141-146. (Pubitemid 36389880)
    • (2003) Journal of Neuroscience Research , vol.72 , Issue.2 , pp. 141-146
    • Michikawa, M.1
  • 25
    • 0036186663 scopus 로고    scopus 로고
    • Serum lipoprotein levels, statin use, and cognitive function in older women
    • Yaffe K, Barrett-Connor E, Lin F, Grady D (2002) Serum lipoprotein levels, statin use, and cognitive function in older women. Arch Neurol 59, 378-384. (Pubitemid 34208144)
    • (2002) Archives of Neurology , vol.59 , Issue.3 , pp. 378-384
    • Yaffe, K.1    Barrett-Connor, E.2    Lin, F.3    Grady, D.4
  • 27
    • 0032956961 scopus 로고    scopus 로고
    • Natural statins and stroke risk
    • Furberg CD (1999) Natural statins and stroke risk. Circulation 99, 185-188. (Pubitemid 29056354)
    • (1999) Circulation , vol.99 , Issue.2 , pp. 185-188
    • Furberg, C.D.1
  • 29
    • 67649252917 scopus 로고    scopus 로고
    • Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study
    • Cramer C, Haan MN, Galea S, Langa KM, Kalbfleisch JD (2008) Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study. Neurology 71, 344-350.
    • (2008) Neurology , vol.71 , pp. 344-350
    • Cramer, C.1    Haan, M.N.2    Galea, S.3    Langa, K.M.4    Kalbfleisch, J.D.5
  • 30
    • 18144419392 scopus 로고    scopus 로고
    • APOE genotype, cholesterol level, lipid-lowering treatment, and dementia: The Three-City Study
    • DOI 10.1212/01.WNL.0000160114.42643.31
    • Dufouil C, Richard F, Fievet N, Dartigues JF, Ritchie K, Tzourio C, Amouyel P, Alperovitch A (2005) APOE genotype, cholesterol level, lipid-lowering treatment, and dementia: The Three-City Study. Neurology 64, 1531-1538. (Pubitemid 40617688)
    • (2005) Neurology , vol.64 , Issue.9 , pp. 1531-1538
    • Dufouil, C.1    Richard, F.2    Fievet, N.3    Dartigues, J.F.4    Ritchie, K.5    Tzourio, C.6    Amouyel, P.7    Alperovitch, A.8
  • 31
    • 58249089520 scopus 로고    scopus 로고
    • Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study
    • Haag MD, Hofman A, Koudstaal PJ, Stricker BH, Breteler MM (2009) Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study. J Neurol Neurosurg Psychiatry 80, 13-17.
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , pp. 13-17
    • Haag, M.D.1    Hofman, A.2    Koudstaal, P.J.3    Stricker, B.H.4    Breteler, M.M.5
  • 36
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20, 536 high-risk individuals: A randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group
    • Heart Protection Study Collaborative Group (2002) MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20, 536 high-risk individuals: A randomised placebo-controlled trial. Lancet 360, 7-22.
    • (2002) Lancet , vol.360 , pp. 7-22
  • 37
    • 33745739157 scopus 로고    scopus 로고
    • Circulating cholesterol levels, apolipoprotein E genotype and dementia severity influence the benefit of atorvastatin treatment in Alzheimer's disease: Results of the Alzheimer's Disease Cholesterol-Lowering Treatment (ADCLT) trial
    • DOI 10.1111/j.1600-0404.2006.00690.x
    • Sparks DL, Connor DJ, Sabbagh MN, Petersen RB, Lopez J, Browne P (2006) Circulating cholesterol levels, apolipopro-tein E genotype and dementia severity influence the benefit of atorvastatin treatment in Alzheimer's disease: Results of the Alzheimer's Disease Cholesterol-Lowering Treatment (ADCLT) trial. Acta Neurol Scand Suppl 185, 3-7. (Pubitemid 44015218)
    • (2006) Acta Neurologica Scandinavica , vol.114 , Issue.SUPPL. 185 , pp. 3-7
    • Sparks, D.L.1    Connor, D.J.2    Sabbagh, M.N.3    Petersen, R.B.4    Lopez, J.5    Browne, P.6
  • 40
    • 0037470137 scopus 로고    scopus 로고
    • The transmembrane domain of the amyloid precursor protein in microsomal membranes is on both sides shorter than predicted
    • DOI 10.1074/jbc.M210047200
    • Grziwa B, Grimm MO, Masters CL, Beyreuther K, Hartmann T, Lichtenthaler SF (2003) The transmembrane domain of the amyloid precursor protein in microsomal membranes is on both sides shorter than predicted. J Biol Chem 278, 6803-6808. (Pubitemid 36800669)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.9 , pp. 6803-6808
    • Grziwa, B.1    Grimm, M.O.W.2    Masters, C.L.3    Beyreuther, K.4    Hartmann, T.5    Lichtenthaler, S.F.6
  • 41
    • 0037710127 scopus 로고    scopus 로고
    • Cholesterol homeostasis and function in neurons of the central nervous system
    • Pfrieger FW (2003) Cholesterol homeostasis and function in neurons of the central nervous system. Cell Mol Life Sci 60, 1158-1171. (Pubitemid 36791918)
    • (2003) Cellular and Molecular Life Sciences , vol.60 , Issue.6 , pp. 1158-1171
    • Pfrieger, F.W.1
  • 42
    • 23444447665 scopus 로고    scopus 로고
    • Pleiotropic effects of statins in atherosclerosis: Role on endothelial function, inflammation and immunomodulation
    • Arnaud C, Mach F (2005) Pleiotropic effects of statins in atherosclerosis: Role on endothelial function, inflammation and immunomodulation. Arch Mal Coeur Vaiss 98, 661-666.
    • (2005) Arch Mal Coeur Vaiss , vol.98 , pp. 661-666
    • Arnaud, C.1    MacH, F.2
  • 43
    • 0028801536 scopus 로고
    • Cholesterol for synthesis of myelinismade locally, not imported into brain
    • Jurevics H, Morell P (1995) Cholesterol for synthesis of myelinismade locally, not imported into brain.J Neurochem 64, 895-901.
    • (1995) J Neurochem , vol.64 , pp. 895-901
    • Jurevics, H.1    Morell, P.2
  • 44
    • 0034663336 scopus 로고    scopus 로고
    • Astrocyte lipoproteins, effects of apoE on neuronal function, and role of apoE in amyloid-β deposition in vivo
    • DOI 10.1002/1097-0029(20000815)50:4<297::AID-JEMT9>3.0.CO;2-C
    • Fagan AM, Holtzman DM (2000) Astrocyte lipoproteins, effects of apoE on neuronal function, and role of apoE in amyloid-beta deposition in vivo. Microsc Res Tech 50, 297-304. (Pubitemid 30651170)
    • (2000) Microscopy Research and Technique , vol.50 , Issue.4 , pp. 297-304
    • Fagan, A.M.1    Holtzman, D.M.2
  • 45
    • 0037359765 scopus 로고    scopus 로고
    • Apolipoprotein e and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease
    • Poirier J (2003) Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease. Trends Mol Med 9, 94-101.
    • (2003) Trends Mol Med , vol.9 , pp. 94-101
    • Poirier, J.1
  • 48
    • 0035856407 scopus 로고    scopus 로고
    • On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells
    • DOI 10.1016/S0304-3940(01)02277-7, PII S0304394001022777
    • Bogdanovic N, Bretillon L, Lund EG, Diczfalusy U, Lann-felt L, Winblad B, Russell DW, Bjorkhem I (2001) On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells. Neurosci Lett 314, 45-48. (Pubitemid 33043802)
    • (2001) Neuroscience Letters , vol.314 , Issue.1-2 , pp. 45-48
    • Bogdanovic, N.1    Bretillon, L.2    Lund, E.G.3    Diczfalusy, U.4    Lannfelt, L.5    Winblad, B.6    Russell, D.W.7    Bjorkhem, I.8
  • 56
    • 0242383360 scopus 로고    scopus 로고
    • Cholesterol, a modulator of membrane-associated Abeta-fibrillogenesis
    • McLaurin J, Darabie AA, Morrison MR (2003) Cholesterol, a modulator of membrane-associated Abeta-fibrillogenesis. Pharmacopsychiatry 36 (Suppl 2) , S130-S135.
    • (2003) Pharmacopsychiatry , vol.36 , Issue.SUPPL. 2
    • McLaurin, J.1    Darabie, A.A.2    Morrison, M.R.3
  • 59
    • 0023280054 scopus 로고
    • Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain
    • Pitas RE, Boyles JK, Lee SH, Hui D, Weisgraber KH (1987) Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B, E (LDL) receptors in the brain. J Biol Chem 262, 14352-14360. (Pubitemid 17152101)
    • (1987) Journal of Biological Chemistry , vol.262 , Issue.29 , pp. 14352-14360
    • Pitas, R.E.1    Boyles, J.K.2    Lee, S.H.3    Hui, D.4    Weisgraber, K.H.5
  • 61
    • 0023764870 scopus 로고
    • Familial hypercholesterolemia and apolipoprotein E4
    • Eto M, Watanabe K, Chonan N, Ishii K (1988) Familial hypercholesterolemia and apolipoprotein E4. Atherosclerosis 72, 123-128.
    • (1988) Atherosclerosis , vol.72 , pp. 123-128
    • Eto, M.1    Watanabe, K.2    Chonan, N.3    Ishii, K.4
  • 62
    • 0027477297 scopus 로고
    • Apolipoprotein E polymorphism is associated with plasma cholesterol response in a 7-day hospitalization study for metabolic and dietary control in NIDDM
    • Murakami K, Shimizu M, Yamada N, Ishibashi S, Shimano H, Yazaki Y, Akanuma Y (1993) Apolipoprotein E polymorphism is associated with plasma cholesterol response in a 7-day hospitalization study for metabolic and dietary control in NIDDM. Diabetes Care 16, 564-569. (Pubitemid 23097201)
    • (1993) Diabetes Care , vol.16 , Issue.4 , pp. 564-569
    • Murakami, K.1    Shimizu, M.2    Yamada, N.3    Ishibashi, S.4    Shimano, H.5    Yazaki, Y.6    Akanuma, Y.7
  • 65
    • 0029072551 scopus 로고
    • Interactions of apolipoprotein e geno type, total cholesterol level, age, and sex in prediction of Alzheimer's disease: A case-control study
    • Jarvik GP, Wijsman EM, Kukull WA, Schellenberg GD, Yu C, Larson EB (1995) Interactions of apolipoprotein E geno type, total cholesterol level, age, and sex in prediction of Alzheimer's disease: A case-control study. Neurology 45, 1092-1096.
    • (1995) Neurology , vol.45 , pp. 1092-1096
    • Jarvik, G.P.1    Wijsman, E.M.2    Kukull, W.A.3    Schellenberg, G.D.4    Yu, C.5    Larson, E.B.6
  • 66
    • 0032926539 scopus 로고    scopus 로고
    • Apolipoprotein E genetic variation and Alzheimer's disease. A meta-analysis
    • DOI 10.1159/000017120
    • Rubinsztein DC, Easton DF (1999) Apolipoprotein E genetic variation and Alzheimer's disease. A meta-analysis. Dement Geriatr Cogn Disord 10, 199-209. (Pubitemid 29224496)
    • (1999) Dementia and Geriatric Cognitive Disorders , vol.10 , Issue.3 , pp. 199-209
    • Rubinsztein, D.C.1    Easton, D.F.2
  • 69
    • 0028991404 scopus 로고
    • Apolipoprotein e epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy
    • Greenberg SM, Rebeck GW, Vonsattel JP, Gomez-Isla T, Hyman BT (1995) Apolipoprotein E epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy. Ann Neurol 38, 254-259.
    • (1995) Ann Neurol , vol.38 , pp. 254-259
    • Greenberg, S.M.1    Rebeck, G.W.2    Vonsattel, J.P.3    Gomez-Isla, T.4    Hyman, B.T.5
  • 74
    • 0032055127 scopus 로고    scopus 로고
    • Apolipoprotein J (clusterin) induces cholesterol export from macrophage-foam cells: A potential anti-atherogenic function?
    • Gelissen IC, Hochgrebe T, Wilson MR, Easterbrook-Smith SB, Jessup W, Dean RT, Brown AJ (1998) Apolipoprotein J (clusterin) induces cholesterol export from macrophage-foam cells: A potential anti-atherogenic function? Biochem J 331 (Pt 1) , 231-237. (Pubitemid 28163979)
    • (1998) Biochemical Journal , vol.331 , Issue.1 , pp. 231-237
    • Gelissen, I.C.1    Hochgrebe, T.2    Wilson, M.R.3    Easterbrook-Smith, S.B.4    Jessup, W.5    Dean, R.T.6    Brown, A.J.7
  • 76
    • 34247506244 scopus 로고    scopus 로고
    • Transport pathways for clearance of human Alzheimer's amyloid β-peptide and apolipoproteins E and J in the mouse central nervous system
    • DOI 10.1038/sj.jcbfm.9600419, PII 9600419
    • Bell RD, Sagare AP, Friedman AE, Bedi GS, Holtzman DM, Deane R, Zlokovic BV (2007) Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteinsEandJinthe mouse central nervous system. J Cereb Blood Flow Metab 27, 909-918. (Pubitemid 46659038)
    • (2007) Journal of Cerebral Blood Flow and Metabolism , vol.27 , Issue.5 , pp. 909-918
    • Bell, R.D.1    Sagare, A.P.2    Friedman, A.E.3    Bedi, G.S.4    Holtzman, D.M.5    Deane, R.6    Zlokovic, B.V.7
  • 77
    • 34547823043 scopus 로고    scopus 로고
    • The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures
    • DOI 10.1096/fj.06-7986com
    • Yerbury JJ, Poon S, Meehan S, Thompson B, Kumita JR, Dobson CM, Wilson MR (2007) The extracellular chaper-one clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures. FASEB J 21, 2312-2322. (Pubitemid 47230661)
    • (2007) FASEB Journal , vol.21 , Issue.10 , pp. 2312-2322
    • Yerbury, J.J.1    Poon, S.2    Meehan, S.3    Thompson, B.4    Kumita, J.R.5    Dobson, C.M.6    Wilson, M.R.7
  • 78
    • 0028921915 scopus 로고
    • Characterization of apolipoprotein J-Alzheimer's A beta interaction
    • Matsubara E, Frangione B, Ghiso J (1995) Characterization of apolipoprotein J-Alzheimer's A beta interaction. J Biol Chem 270, 7563-7567.
    • (1995) J Biol Chem , vol.270 , pp. 7563-7567
    • Matsubara, E.1    Frangione, B.2    Ghiso, J.3
  • 80
    • 40549105438 scopus 로고    scopus 로고
    • Association between genetic variants in SORL1 and autopsy-confirmed Alzheimer disease
    • DOI 10.1212/01.wnl.0000280581.39755.89
    • Lee JH, Cheng R, Honig LS, Vonsattel JP, Clark L, Mayeux R (2008) Association between genetic variants in SORL1 and autopsy-confirmed Alzheimer disease. Neurology 70, 887-889. (Pubitemid 351367519)
    • (2008) Neurology , vol.70 , Issue.11 , pp. 887-889
    • Lee, J.H.1    Cheng, R.2    Honig, L.S.3    Vonsattel, J.-P.G.4    Clark, L.5    Mayeux, R.6
  • 81
    • 34548617769 scopus 로고    scopus 로고
    • Association between genetic variants in sortilin-related receptor 1 (SORL1) and Alzheimer's disease in adults with Down syndrome
    • DOI 10.1016/j.neulet.2007.08.042, PII S0304394007009305
    • Lee JH, Chulikavit M, Pang D, Zigman WB, Silverman W, Schupf N (2007) Association between genetic variants in sortilin-related receptor 1 (SORL1) and Alzheimer's disease in adults with Down syndrome. Neurosci Lett 425, 105-109. (Pubitemid 47410369)
    • (2007) Neuroscience Letters , vol.425 , Issue.2 , pp. 105-109
    • Lee, Joseph.H.1    Chulikavit, M.2    Pang, D.3    Zigman, W.B.4    Silverman, W.5    Schupf, N.6
  • 82
    • 49849086825 scopus 로고    scopus 로고
    • SORL1 is genetically associated with increased risk for late-onset Alzheimer diseaseinthe Belgian population
    • Bettens K, Brouwers N, Engelborghs S, De Deyn PP, Van Broeckhoven C, Sleegers K (2008) SORL1 is genetically associated with increased risk for late-onset Alzheimer diseaseinthe Belgian population.Hum Mutat 29, 769-770.
    • (2008) Hum Mutat , vol.29 , pp. 769-770
    • Bettens, K.1    Brouwers, N.2    Engelborghs, S.3    De Deyn, P.P.4    Van Broeckhoven, C.5    Sleegers, K.6
  • 89
    • 54049099305 scopus 로고    scopus 로고
    • The neuronal sortilin-related receptor gene SORL1 and late-onset Alzheimer's disease
    • Lee JH, Barral S, Reitz C (2008) The neuronal sortilin-related receptor gene SORL1 and late-onset Alzheimer's disease. Curr Neurol Neurosci Rep 8, 384-391.
    • (2008) Curr Neurol Neurosci Rep , vol.8 , pp. 384-391
    • Lee, J.H.1    Barral, S.2    Reitz, C.3
  • 90
    • 55149121151 scopus 로고    scopus 로고
    • Possible association between SORL1 and Alzheimer disease? Reanalysing the data of Shibata et al
    • Lee JH, Shibata N, Cheng R, Mayeux R (2008) Possible association between SORL1 and Alzheimer disease? Reanalysing the data of Shibata et al. Dement Geriatr Cogn Disor 26, 482.
    • (2008) Dement Geriatr Cogn Disor , vol.26 , pp. 482
    • Lee, J.H.1    Shibata, N.2    Cheng, R.3    Mayeux, R.4
  • 93
    • 37349015908 scopus 로고    scopus 로고
    • Association between SORL1 and Alzheimer's disease in a genome-wide study
    • DOI 10.1097/WNR.0b013e3282f13e7a, PII 0000175620071119000002
    • Meng Y, Lee JH, Cheng R, St George-Hyslop P, Mayeux R, Farrer LA (2007) Association between SORL1 and Alzheimer's disease in a genome-wide study. Neuroreport 18, 1761-1764. (Pubitemid 350303747)
    • (2007) NeuroReport , vol.18 , Issue.17 , pp. 1761-1764
    • Meng, Y.1    Lee, J.H.2    Cheng, R.3    St George-Hyslop, P.4    Mayeux, R.5    Farrer, L.A.6
  • 95
    • 48649109424 scopus 로고    scopus 로고
    • Genetic association between SORL1 polymorphisms and Alzheimer's disease in a Japanese population
    • Shibata N, Ohnuma T, Baba H, Higashi S, Nishioka K, Arai H (2008) Genetic association between SORL1 polymorphisms and Alzheimer's disease in a Japanese population. Dement Geriatr Cogn Disord 26, 161-164.
    • (2008) Dement Geriatr Cogn Disord , vol.26 , pp. 161-164
    • Shibata, N.1    Ohnuma, T.2    Baba, H.3    Higashi, S.4    Nishioka, K.5    Arai, H.6
  • 96
  • 99
    • 55949110600 scopus 로고    scopus 로고
    • Analyses of the National Institute on Aging Late-Onset Alzheimer's Disease Family Study: Implication of additional loci
    • Lee JH, Cheng R, Graff-Radford N, Foroud T, Mayeux R (2008) Analyses of the National Institute on Aging Late-Onset Alzheimer's Disease Family Study: Implication of additional loci. Arch Neurol 65, 1518-1526.
    • (2008) Arch Neurol , vol.65 , pp. 1518-1526
    • Lee, J.H.1    Cheng, R.2    Graff-Radford, N.3    Foroud, T.4    Mayeux, R.5
  • 103
    • 71449125786 scopus 로고    scopus 로고
    • Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance
    • Kim J, Castellano JM, Jiang H, Basak JM, Parsadanian M, Pham V, Mason SM, Paul SM, Holtzman DM (2009) Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance. Neuron 64, 632-644.
    • (2009) Neuron , vol.64 , pp. 632-644
    • Kim, J.1    Castellano, J.M.2    Jiang, H.3    Basak, J.M.4    Parsadanian, M.5    Pham, V.6    Mason, S.M.7    Paul, S.M.8    Holtzman, D.M.9
  • 107
    • 10044242726 scopus 로고    scopus 로고
    • Genetic association of low density lipoprotein receptor and Alzheimer's disease
    • DOI 10.1016/j.neurobiolaging.2004.09.001, PII S0197458004002738
    • Gopalraj RK, Zhu H, Kelly JF, Mendiondo M, Pulliam JF, Bennett DA, Estus S (2005) Genetic association of low density lipoprotein receptor and Alzheimer's disease. Neurobiol Aging 26, 1-7. (Pubitemid 39600585)
    • (2005) Neurobiology of Aging , vol.26 , Issue.1 , pp. 1-7
    • Gopalraj, R.K.1    Zhu, H.2    Kelly, J.F.3    Mendiondo, M.4    Pulliam, J.F.5    Bennett, D.A.6    Estus, S.7
  • 112
    • 11144316145 scopus 로고    scopus 로고
    • Biological evidence for inheritance of exceptional longevity
    • DOI 10.1016/j.mad.2004.08.026, PII S004763740400209X, The Voyage to Old Age: Searching for Human Longevity Genes
    • Atzmon G, Rincon M, Rabizadeh P, Barzilai N (2005) Biological evidence for inheritance of exceptional longevity. Mech Ageing Dev 126, 341-345. (Pubitemid 40038355)
    • (2005) Mechanisms of Ageing and Development , vol.126 , Issue.2 , pp. 341-345
    • Atzmon, G.1    Rincon, M.2    Rabizadeh, P.3    Barzilai, N.4
  • 113
    • 32844464298 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein (CETP) polymorphism modifies the Alzheimer's disease risk associated with APOE ε4 allele
    • DOI 10.1007/s00415-005-0945-2
    • Rodriguez E, Mateo I, Infante J, Llorca J, Berciano J, Com-barros O (2006) Cholesteryl ester transfer protein (CETP) polymorphism modifies the Alzheimer's disease risk associated with APOE epsilon4 allele. J Neurol 253, 181-185. (Pubitemid 43255888)
    • (2006) Journal of Neurology , vol.253 , Issue.2 , pp. 181-185
    • Rodriguez, E.1    Mateo, I.2    Infante, J.3    Llorca, J.4    Berciano, J.5    Combarros, O.6
  • 115
    • 30044438463 scopus 로고    scopus 로고
    • Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice
    • DOI 10.1074/jbc.M504513200
    • Koldamova R, Staufenbiel M, Lefterov I (2005) Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice. J Biol Chem 280, 43224-43235. (Pubitemid 43049289)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.52 , pp. 43224-43235
    • Koldamova, R.1    Staufenbiel, M.2    Lefterov, I.3
  • 120
    • 34247120141 scopus 로고    scopus 로고
    • Gender-specific association of ATP-binding cassette transporter 1 (ABCA1) polymorphisms with the risk of late-onset Alzheimer's disease
    • DOI 10.1016/j.neurobiolaging.2006.04.005, PII S0197458006001199
    • Sundar PD, Feingold E, Minster RL, DeKosky ST, Kam-boh MI (2007) Gender-specific association of ATP-binding cassette transporter 1 (ABCA1) polymorphisms with the risk of late-onset Alzheimer's disease. Neurobiol Aging 28, 856-862. (Pubitemid 46589738)
    • (2007) Neurobiology of Aging , vol.28 , Issue.6 , pp. 856-862
    • Sundar, P.D.1    Feingold, E.2    Minster, R.L.3    DeKosky, S.T.4    Kamboh, M.I.5
  • 126
    • 70049090631 scopus 로고    scopus 로고
    • No association of DAPK1 and ABCA2 SNPs on chromosome 9 with Alzheimer's disease
    • Minster RL, DeKosky ST, Kamboh MI (2009) No association of DAPK1 and ABCA2 SNPs on chromosome 9 with Alzheimer's disease. Neurobiol Aging 30, 1890-1891.
    • (2009) Neurobiol Aging , vol.30 , pp. 1890-1891
    • Minster, R.L.1    Dekosky, S.T.2    Kamboh, M.I.3
  • 129
    • 34047250984 scopus 로고    scopus 로고
    • Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-β peptide generation
    • DOI 10.1074/jbc.M607831200
    • Kim WS, Rahmanto AS, Kamili A, Rye KA, Guillemin GJ, Gelissen IC, Jessup W, Hill AF, Garner B (2007) Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation. J Biol Chem 282, 2851-2861. (Pubitemid 47084333)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.5 , pp. 2851-2861
    • Kim, W.S.1    Rahmanto, A.S.2    Kamili, A.3    Rye, K.-A.4    Guillemin, G.J.5    Gelissen, I.C.6    Jessup, W.7    Hill, A.F.8    Garner, B.9
  • 132
    • 0035957222 scopus 로고    scopus 로고
    • Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits Aβ aggregation and toxicity
    • DOI 10.1021/bi002186k
    • Koldamova RP, Lefterov IM, Lefterova MI, Lazo JS (2001) Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity. Biochemistry 40, 3553-3560. (Pubitemid 32242812)
    • (2001) Biochemistry , vol.40 , Issue.12 , pp. 3553-3560
    • Koldamova, R.P.1    Lefterov, I.M.2    Lefterova, M.I.3    Lazo, J.S.4
  • 134
    • 0343907873 scopus 로고    scopus 로고
    • Association of the apolipoprotein A-IV codon 360 mutation in patients with Alzheimer's disease
    • DOI 10.1016/S0304-3940(97)00500-4, PII S0304394097005004
    • Csaszar A, Kalman J, Szalai C, Janka Z, Romics L (1997) Association of the apolipoprotein A-IV codon 360 mutation in patients with Alzheimer's disease.Neurosci Lett230, 151-154. (Pubitemid 27342188)
    • (1997) Neuroscience Letters , vol.230 , Issue.3 , pp. 151-154
    • Csaszar, A.1    Kalman, J.2    Szalai, C.3    Janka, Z.4    Romics, L.5
  • 135
    • 0032512865 scopus 로고    scopus 로고
    • Apolipoprotein AIV codon 360 mutation increases with human aging and is not associated with Alzheimer's disease
    • DOI 10.1016/S0304-3940(98)00025-1, PII S0304394098000251
    • Merched A, Xia Y, Papadopoulou A, Siest G, Visvikis S (1998) Apolipoprotein AIV codon 360 mutation increases with human aging and is not associated with Alzheimer's disease. Neurosci Lett 242, 117-119. (Pubitemid 28083006)
    • (1998) Neuroscience Letters , vol.242 , Issue.2 , pp. 117-119
    • Merched, A.1    Xia, Y.2    Papadopoulou, A.3    Siest, G.4    Visvikis, S.5
  • 136
    • 0032738743 scopus 로고    scopus 로고
    • No association between apolipoprotein A-IV codon 360 mutation and late-onset Alzheimer's disease in the Japanese population
    • DOI 10.1159/000017192
    • Ji Y, Urakami K, Adachi Y, Nakashima K (1999) No association between apolipoprotein A-IV codon 360 mutation and late-onset Alzheimer's disease in the Japanese population. Dement Geriatr Cogn Disord 10, 473-475. (Pubitemid 29512014)
    • (1999) Dementia and Geriatric Cognitive Disorders , vol.10 , Issue.6 , pp. 473-475
    • Ji, Y.1    Urakami, K.2    Adachi, Y.3    Nakashima, K.4
  • 137
    • 0023090682 scopus 로고
    • Association of an apolipoprotein CII allele with familial dementia of the Alzheimer type
    • Schellenberg GD, Deeb SS, Boehnke M, Bryant EM, Martin GM, Lampe TH, Bird TD (1987) Association of an apolipoprotein CII allele with familial dementia of the Alzheimer type. J Neurogenet 4, 97-108. (Pubitemid 17050015)
    • (1987) Journal of Neurogenetics , vol.4 , Issue.2-3 , pp. 97-108
    • Schellenberg, G.D.1    Deeb, S.S.2    Boehnke, M.3
  • 140
    • 2542580859 scopus 로고    scopus 로고
    • Increased caveolin-1 expression in Alzheimer's disease brain
    • DOI 10.1016/j.neurobiolaging.2003.07.004, PII S0197458003001866
    • Gaudreault SB, Dea D, Poirier J (2004) Increased caveolin-1 expression in Alzheimer's disease brain. Neurobiol Aging 25, 753-759. (Pubitemid 38698250)
    • (2004) Neurobiology of Aging , vol.25 , Issue.6 , pp. 753-759
    • Gaudreault, S.B.1    Dea, D.2    Poirier, J.3
  • 143
  • 144
    • 74149083432 scopus 로고    scopus 로고
    • Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology beforeorafter the onsetofamyloid plaques in mouse models of Alzheimer's disease
    • Hudry E, Van Dam D, Kulik W, De Deyn PP, Stet FS, Ahouansou O, Benraiss A, Delacourte A, Bougneres P, Aubourg P, Cartier N (2010) Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology beforeorafter the onsetofamyloid plaques in mouse models of Alzheimer's disease. Mol Ther 18, 44-53.
    • (2010) Mol Ther , vol.18 , pp. 44-53
    • Hudry, E.1    Van Dam, D.2    Kulik, W.3    De Deyn, P.P.4    Stet, F.S.5    Ahouansou, O.6    Benraiss, A.7    Delacourte, A.8    Bougneres, P.9    Aubourg, P.10    Cartier, N.11
  • 145
    • 2542523048 scopus 로고    scopus 로고
    • Intronic CYP46 polymorphism along with ApoE genotype in sporadic Alzheimer Disease: From risk factors to disease modulators
    • DOI 10.1016/j.neurobiolaging.2003.08.004, PII S019745800300188X
    • Borroni B, Archetti S, Agosti C, Akkawi N, Brambilla C, Caimi L, Caltagirone C, Di Luca M, Padovani A (2004) Intronic CYP46 polymorphism along with ApoE genotype in sporadic Alzheimer Disease: From risk factors to disease modulators. Neurobiol Aging 25, 747-751. (Pubitemid 38698249)
    • (2004) Neurobiology of Aging , vol.25 , Issue.6 , pp. 747-751
    • Borroni, B.1    Archetti, S.2    Agosti, C.3    Akkawi, N.4    Brambilla, C.5    Caimi, L.6    Caltagirone, C.7    Di Luca, M.8    Padovani, A.9
  • 146
    • 3042701772 scopus 로고    scopus 로고
    • APOE promoter, ACE1 and CYP46 polymorphisms and β-amyloid in Alzheimer's disease
    • DOI 10.1097/00001756-200401190-00019
    • Chalmers KA, Culpan D, Kehoe PG, Wilcock GK, Hughes A, Love S (2004) APOE promoter, ACE1 and CYP46 polymorphisms and beta-amyloid in Alzheimer's disease. Neuroreport 15, 95-98. (Pubitemid 41614979)
    • (2004) NeuroReport , vol.15 , Issue.1 , pp. 95-98
    • Chalmers, K.A.1    Culpan, D.2    Kehoe, P.G.3    Wilcock, G.K.4    Hughes, A.5    Love, S.6
  • 149
    • 0034307463 scopus 로고    scopus 로고
    • The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegener-ation and oxidative stress
    • Greeve I, Hermans-Borgmeyer I, Brellinger C, Kasper D, Gomez-Isla T, Behl C, Levkau B, Nitsch RM (2000) The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegener-ation and oxidative stress. J Neurosci 20, 7345-7352.
    • (2000) J Neurosci , vol.20 , pp. 7345-7352
    • Greeve, I.1    Hermans-Borgmeyer, I.2    Brellinger, C.3    Kasper, D.4    Gomez-Isla, T.5    Behl, C.6    Levkau, B.7    Nitsch, R.M.8
  • 153
    • 40849121018 scopus 로고    scopus 로고
    • Lack of association of hepatic lipase polymorphisms with late-onset Alzheimer's disease
    • DOI 10.1016/j.neurobiolaging.2006.11.015, PII S0197458006004386
    • Zhu H, Taylor JW, Bennett DA, Younkin SG, Estus S (2008) Lack of association of hepatic lipase polymorphisms with late-onset Alzheimer's disease. Neurobiol Aging 29, 793-794. (Pubitemid 351400821)
    • (2008) Neurobiology of Aging , vol.29 , Issue.5 , pp. 793-794
    • Zhu, H.1    Taylor, J.W.2    Bennett, D.A.3    Younkin, S.G.4    Estus, S.5
  • 154
    • 0034663179 scopus 로고    scopus 로고
    • Roles for lipoprotein lipase in Alzheimer's disease: An association study
    • DOI 10.1002/1097-0029(20000815)50:4<291::AID-JEMT8>3.0.CO;2-L
    • Baum L, Wiebusch H, Pang CP (2000) Roles for lipoprotein lipase in Alzheimer's disease: An association study. Microsc Res Tech 50, 291-296. (Pubitemid 30651169)
    • (2000) Microscopy Research and Technique , vol.50 , Issue.4 , pp. 291-296
    • Baum, L.1    Wiebusch, H.2    Pang, C.P.3
  • 155
    • 33748756773 scopus 로고    scopus 로고
    • A polymorphism in lipoprotein lipase affects the severity of Alzheimer's disease pathophysiology
    • DOI 10.1111/j.1460-9568.2006.05007.x
    • Blain JF, Aumont N, Theroux L, Dea D, Poirier J (2006) A polymorphism in lipoprotein lipase affects the severity of Alzheimer's disease pathophysiology. Eur J Neurosci 24, 1245-1251. (Pubitemid 44401648)
    • (2006) European Journal of Neuroscience , vol.24 , Issue.5 , pp. 1245-1251
    • Blain, J.-F.1    Aumont, N.2    Theroux, L.3    Dea, D.4    Poirier, J.5
  • 156
    • 4344610458 scopus 로고    scopus 로고
    • The H+ allele of the lipoprotein lipase (LPL) HindIII intronic polymorphism and the risk for sporadic late-onset Alzheimer's disease
    • DOI 10.1016/j.neulet.2004.05.111, PII S0304394004007219
    • Scacchi R, Gambina G, Broggio E, Moretto G, Ruggeri M, Corbo RM (2004) The H+ allele of the lipoprotein lipase (LPL) HindIII intronic polymorphism and the risk for sporadic late-onset Alzheimer's disease. Neurosci Lett 367, 177-180. (Pubitemid 39141221)
    • (2004) Neuroscience Letters , vol.367 , Issue.2 , pp. 177-180
    • Scacchi, R.1    Gambina, G.2    Broggio, E.3    Moretto, G.4    Ruggeri, M.5    Corbo, R.M.6
  • 158
    • 65649105035 scopus 로고    scopus 로고
    • Clearance of amyloid-beta peptide across the blood-brain barrier: Implication for therapies in Alzheimer's disease
    • Deane R, Bell RD, Sagare A, Zlokovic BV (2009) Clearance of amyloid-beta peptide across the blood-brain barrier: Implication for therapies in Alzheimer's disease. CNS Neu-rol Disord Drug Targets 8, 16-30.
    • (2009) CNS Neu-rol Disord Drug Targets , vol.8 , pp. 16-30
    • Deane, R.1    Bell, R.D.2    Sagare, A.3    Zlokovic, B.V.4
  • 161
    • 34748897213 scopus 로고    scopus 로고
    • Amyloid Precursor Protein Regulates Brain Apolipoprotein E and Cholesterol Metabolism through Lipoprotein Receptor LRP1
    • DOI 10.1016/j.neuron.2007.08.008, PII S0896627307006204
    • Liu Q, Zerbinatti CV, Zhang J, Hoe HS, Wang B, Cole SL, Herz J, Muglia L, Bu G (2007) Amyloid precursor protein regulates brain apolipoprotein Eand cholesterol metabolism through lipoprotein receptor LRP1. Neuron 56, 66-78. (Pubitemid 47484175)
    • (2007) Neuron , vol.56 , Issue.1 , pp. 66-78
    • Liu, Q.1    Zerbinatti, C.V.2    Zhang, J.3    Hoe, H.-S.4    Wang, B.5    Cole, S.L.6    Herz, J.7    Muglia, L.8    Bu, G.9
  • 164
    • 34047268145 scopus 로고    scopus 로고
    • Knockdown of ACAT-1 reduces amyloidogenic processing of APP
    • DOI 10.1016/j.febslet.2007.03.056, PII S0014579307003109
    • Huttunen HJ, Greco C, Kovacs DM (2007) Knockdown of ACAT-1 reduces amyloidogenic processing of APP. FEBS Lett 581, 1688-1692. (Pubitemid 46546584)
    • (2007) FEBS Letters , vol.581 , Issue.8 , pp. 1688-1692
    • Huttunen, H.J.1    Greco, C.2    Kovacs, D.M.3
  • 167
    • 0030791972 scopus 로고    scopus 로고
    • Presenilin-I, presenilin-II, and VLDL-R associations in early onset Alzheimer's disease [3]
    • Brookes AJ, Howell WM, Woodburn K, Johnstone EC, Carothers A (1997) Presenilin-I, presenilin-II, and VLDL-R associations in early onset Alzheimer's disease. Lancet 350, 336-337. (Pubitemid 27351120)
    • (1997) Lancet , vol.350 , Issue.9074 , pp. 336-337
    • Brookes, A.J.1    Howell, W.M.2    Woodburn, K.3    Johnstone, E.C.4    Carothers, A.5
  • 168
    • 0032450065 scopus 로고    scopus 로고
    • The very low density lipoprotein (VLDL) receptor is a genetic susceptibility factor for Alzheimer disease in a European Caucasian population
    • Helbecque N, Richard F, Cottel D, Neuman E, Guez D, Amouyel P (1998) The very low density lipoprotein (VLDL) receptor is a genetic susceptibility factor for Alzheimer disease in a European Caucasian population. Alzheimer Dis Assoc Disord 12, 368-371. (Pubitemid 29050753)
    • (1998) Alzheimer Disease and Associated Disorders , vol.12 , Issue.4 , pp. 368-371
    • Helbecque, N.1    Richard, F.2    Cottel, D.3    Neuman, E.4    Guez, D.5    Amouyel, P.6
  • 171
    • 0031958481 scopus 로고    scopus 로고
    • Genetic risk factors in Japanese Alzheimer's disease patients: α1-ACT, VLDLR, and ApoE
    • DOI 10.1016/S0197-4580(98)00035-9, PII S0197458098000359
    • Yamanaka H, Kamimura K, Tanahashi H, Takahashi K, Asada T, Tabira T (1998) Genetic risk factors in Japanese Alzheimer's disease patients: Alpha1-ACT, VLDLR, and ApoE. Neurobiol Aging 19, S43-S46. (Pubitemid 28178937)
    • (1998) Neurobiology of Aging , vol.19 , Issue.SUPPL. 1
    • Yamanaka, H.1    Kamimura, K.2    Tanahashi, H.3    Takahashi, K.4    Asada, T.5    Tabira, T.6
  • 172
    • 0035826546 scopus 로고    scopus 로고
    • Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controls
    • DOI 10.1002/ajmg.1371
    • Perry RT, Collins JS, Harrell LE, Acton RT, Go RC (2001) Investigation of association of 13 polymorphisms in eight genes in southeastern African American Alzheimer disease patients as compared to age-matched controls. Am J Med Genet 105, 332-342. (Pubitemid 32578230)
    • (2001) American Journal of Medical Genetics - Neuropsychiatric Genetics , vol.105 , Issue.4 , pp. 332-342
    • Perry, R.T.1    Collins, J.S.2    Harrell, L.E.3    Acton, R.T.4    Go, R.C.P.5
  • 174
    • 78649510282 scopus 로고    scopus 로고
    • Diabetes, related conditions, and dementia
    • Luchsinger JA (2010) Diabetes, related conditions, and dementia. J Neurol Sci 299, 35-38.
    • (2010) J Neurol Sci , vol.299 , pp. 35-38
    • Luchsinger, J.A.1
  • 178
    • 79955521915 scopus 로고    scopus 로고
    • Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease
    • Li J, Wang YJ, Zhang M, Xu ZQ, Gao CY, Fang CQ, Yan JC, Zhou HD (2011) Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease. Neurology 76, 1485-1491.
    • (2011) Neurology , vol.76 , pp. 1485-1491
    • Li, J.1    Wang, Y.J.2    Zhang, M.3    Xu, Z.Q.4    Gao, C.Y.5    Fang, C.Q.6    Yan, J.C.7    Zhou, H.D.8


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