Association between genetic variants in sortilin-related receptor 1 (SORL1) and Alzheimer's disease in adults with Down syndrome

Neuroscience Letters

Volumn 425, Issue 2, 2007, Pages 105-109

  Lee, Joseph H ^a,b   Chulikavit, Maruit ^a   Pang, Deborah ^a,c   Zigman, Warren B ^c   Silverman, Wayne ^d   Schupf, Nicole ^a,c  

^a NewYork Presbyterian Hospital   (United States)

^b Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^c NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Down syndrome; SORL1

Indexed keywords

AMYLOID PRECURSOR PROTEIN; PROTEIN; SORTILIN RELATED RECEPTOR 1; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DOWN SYNDROME; FEMALE; GENE; GENE LINKAGE DISEQUILIBRIUM; GENE OVEREXPRESSION; GENETIC RISK; GENETIC VARIABILITY; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC EXAMINATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SORL1 GENE;

AGE OF ONSET; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; BRAIN; BRAIN CHEMISTRY; COMORBIDITY; DNA MUTATIONAL ANALYSIS; DOWN SYNDROME; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HOMOZYGOTE; HUMANS; LDL-RECEPTOR RELATED PROTEINS; LINKAGE DISEQUILIBRIUM; MALE; MEMBRANE TRANSPORT PROTEINS; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; RISK FACTORS; VARIATION (GENETICS);

EID: 34548617769     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.08.042     Document Type: Article

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