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Volumn 15, Issue 1, 2004, Pages 95-98

APOE promoter, ACE1 and CYP46 polymorphisms and β-amyloid in Alzheimer's disease

Author keywords

A load; ACE1; Alzheimer's disease; APOE Promoter; CYP46; Polymorphisms

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; DIPEPTIDYL CARBOXYPEPTIDASE; CHOLESTEROL 24 HYDROXYLASE; CHOLESTEROL 24-HYDROXYLASE; STEROID MONOOXYGENASE;

EID: 3042701772     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200401190-00019     Document Type: Article
Times cited : (40)

References (27)
  • 1
    • 0034509668 scopus 로고    scopus 로고
    • Genetic factors in the genesis of Alzheimer's disease
    • St George-Hyslop PH. Genetic factors in the genesis of Alzheimer's disease. Ann NY Acad Sci 924, 1-7 (2000).
    • (2000) Ann NY Acad Sci , vol.924 , pp. 1-7
    • St. George-Hyslop, P.H.1
  • 2
    • 0031918785 scopus 로고    scopus 로고
    • The genetics of Alzheimer disease: Current status and future prospects
    • Blacker D and Tanzi RE. The genetics of Alzheimer disease: current status and future prospects. Arch Neurol 55, 294-296 (1998).
    • (1998) Arch Neurol , vol.55 , pp. 294-296
    • Blacker, D.1    Tanzi, R.E.2
  • 3
    • 0035910317 scopus 로고    scopus 로고
    • Genetic susceptibility factors for Alzheimer's disease
    • Richard F and Amouyel P. Genetic susceptibility factors for Alzheimer's disease. Eur J Pharmacol 412, 1-12 (2001).
    • (2001) Eur J Pharmacol , vol.412 , pp. 1-12
    • Richard, F.1    Amouyel, P.2
  • 4
    • 0038509216 scopus 로고    scopus 로고
    • APOE ε4 favours cerebrovascular over parenchymal deposition of Aβ protein and thereby influences the pathological phenotype of ε4-associated Alzheimer's disease
    • Chalmers KA, Wilcock GK and Love S. APOE ε4 favours cerebrovascular over parenchymal deposition of Aβ protein and thereby influences the pathological phenotype of ε4-associated Alzheimer's disease. Neuropathol Appl Neurobiol 29, 231-238 (2003).
    • (2003) Neuropathol Appl Neurobiol , vol.29 , pp. 231-238
    • Chalmers, K.A.1    Wilcock, G.K.2    Love, S.3
  • 5
    • 17344374322 scopus 로고    scopus 로고
    • A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia
    • Bullido MJ, Artiga MJ, Recuero M, Sastre I, Garcia MA, Aldudo J et al. A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia. Nature Genet 18, 69-71 (1998).
    • (1998) Nature Genet , vol.18 , pp. 69-71
    • Bullido, M.J.1    Artiga, M.J.2    Recuero, M.3    Sastre, I.4    Garcia, M.A.5    Aldudo, J.6
  • 7
    • 0037345672 scopus 로고    scopus 로고
    • Expanding the association between the APOE gene and the risk of Alzheimer's disease: Possible roles for APOE promoter polymorphisms and alterations in APOE transcription
    • Laws SM, Hone E, Gandy SE and Martins RN. Expanding the association between the APOE gene and the risk of Alzheimer's disease: possible roles for APOE promoter polymorphisms and alterations in APOE transcription. J Neurochem 84, 1215-1236 (2003).
    • (2003) J Neurochem , vol.84 , pp. 1215-1236
    • Laws, S.M.1    Hone, E.2    Gandy, S.E.3    Martins, R.N.4
  • 8
    • 0032498118 scopus 로고    scopus 로고
    • Allelic polymorphisms in the transcriptional regulatory region of apolipoprotein E gene
    • Artiga MJ, Bullido MJ, Sastre I, Recuero M, Garcia MA, Aldudo J et al. Allelic polymorphisms in the transcriptional regulatory region of apolipoprotein E gene. FEBS Lett 421, 105-108 (1998).
    • (1998) FEBS Lett , vol.421 , pp. 105-108
    • Artiga, M.J.1    Bullido, M.J.2    Sastre, I.3    Recuero, M.4    Garcia, M.A.5    Aldudo, J.6
  • 9
    • 0033577180 scopus 로고    scopus 로고
    • The -491AA polymorphism in the APOE gene is associated with increased plasma apoE levels in Alzheimer's disease
    • Laws SM, Taddei K, Martins G, Paton A, Fisher C, Clarnette R et al. The -491AA polymorphism in the APOE gene is associated with increased plasma apoE levels in Alzheimer's disease. Neuroreport 10, 879-882 (1999).
    • (1999) Neuroreport , vol.10 , pp. 879-882
    • Laws, S.M.1    Taddei, K.2    Martins, G.3    Paton, A.4    Fisher, C.5    Clarnette, R.6
  • 10
    • 85101728623 scopus 로고    scopus 로고
    • Effect of the APOE promoter polymorphisms on cerebral amyloid peptide deposition in Alzheimer's disease (erratum appears in Lancet 2001 Apr 28;357(9265):1370)
    • Lambert JC, Mann D, Goumidi L, Harris J, Amouyel P, Iwatsubo T et al. Effect of the APOE promoter polymorphisms on cerebral amyloid peptide deposition in Alzheimer's disease (erratum appears in Lancet 2001 Apr 28;357(9265):1370). Lancet 357, 608-619 (2001).
    • (2001) Lancet , vol.357 , pp. 608-619
    • Lambert, J.C.1    Mann, D.2    Goumidi, L.3    Harris, J.4    Amouyel, P.5    Iwatsubo, T.6
  • 11
    • 7344221464 scopus 로고    scopus 로고
    • Pronounced impact of Th1/E47cs mutation compared with -491 at mutation on neural APOE gene expression and risk of developing Alzheimer's disease
    • Lambert JC, Berr C, Pasquier F, Delacourte A, Frigard B, Cottel D et al. Pronounced impact of Th1/E47cs mutation compared with -491 AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease. Hum Mol Genet 7, 1511-1516 (1998).
    • (1998) Hum Mol Genet , vol.7 , pp. 1511-1516
    • Lambert, J.C.1    Berr, C.2    Pasquier, F.3    Delacourte, A.4    Frigard, B.5    Cottel, D.6
  • 13
    • 0032545164 scopus 로고    scopus 로고
    • The -491 A/T polymorphism in the regulatory region of the apolipoprotein e gene and early-onset Alzheimer's disease
    • Roks G, Cruts M, Bullido MJ, Backhovens H, Artiga MJ, Hofman A et al. The -491 A/T polymorphism in the regulatory region of the apolipoprotein E gene and early-onset Alzheimer's disease. Neurosci Lett 258, 65-68 (1998).
    • (1998) Neurosci Lett , vol.258 , pp. 65-68
    • Roks, G.1    Cruts, M.2    Bullido, M.J.3    Backhovens, H.4    Artiga, M.J.5    Hofman, A.6
  • 14
    • 0032503943 scopus 로고    scopus 로고
    • Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE
    • Song YQ, Rogaeva E, Premkumar S, Brindle N, Kawarai T, Orlacchio A et al. Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE. Neurosci Lett 250, 189-192 (1998).
    • (1998) Neurosci Lett , vol.250 , pp. 189-192
    • Song, Y.Q.1    Rogaeva, E.2    Premkumar, S.3    Brindle, N.4    Kawarai, T.5    Orlacchio, A.6
  • 15
    • 0032924870 scopus 로고    scopus 로고
    • Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease
    • Kehoe PG, Russ C, McIlory S, Williams H, Holmans P, Holmes C et al. Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. Nature Genet 21, 71-72 (1999).
    • (1999) Nature Genet , vol.21 , pp. 71-72
    • Kehoe, P.G.1    Russ, C.2    McIlory, S.3    Williams, H.4    Holmans, P.5    Holmes, C.6
  • 17
    • 0035930538 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta); retards a beta aggregation, deposition, fibril formation; and inhibits cytotoxicity
    • Hu J, Igarashi A, Kamata M and Nakagawa H. Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity. J Biol Chem 276, 47863-47868 (2001).
    • (2001) J Biol Chem , vol.276 , pp. 47863-47868
    • Hu, J.1    Igarashi, A.2    Kamata, M.3    Nakagawa, H.4
  • 18
    • 0037119213 scopus 로고    scopus 로고
    • The angiotensin 1-converting enzyme insertion (I)/deletion (D) polymorphism does not influence the extent of amyloid or tau pathology in patients with sporadic Alzheimer's disease
    • Lendon CL, Thaker U, Harris JM, McDonagh AM, Lambert JC, Chartier-Harlin MC et al. The angiotensin 1-converting enzyme insertion (I)/deletion (D) polymorphism does not influence the extent of amyloid or tau pathology in patients with sporadic Alzheimer's disease. Neurosci Lett 328, 314-318 (2002).
    • (2002) Neurosci Lett , vol.328 , pp. 314-318
    • Lendon, C.L.1    Thaker, U.2    Harris, J.M.3    McDonagh, A.M.4    Lambert, J.C.5    Chartier-Harlin, M.C.6
  • 19
    • 0033772113 scopus 로고    scopus 로고
    • Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme a reductase inhibitors
    • Wolozin B, Kellman W, Ruosseau P, Celesia GG and Siegel G. Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Arch Neurol 57, 1439-1443 (2000).
    • (2000) Arch Neurol , vol.57 , pp. 1439-1443
    • Wolozin, B.1    Kellman, W.2    Ruosseau, P.3    Celesia, G.G.4    Siegel, G.5
  • 20
    • 0001504829 scopus 로고    scopus 로고
    • Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides A beta 42 and A beta 40 in vitro and in vivo
    • Fassbender K, Simons M, Bergmann C, Stroick M, Lutjohann D, Keller P et al. Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides A beta 42 and A beta 40 in vitro and in vivo. Proc Natl Acad Sci USA 98, 5856-5861 (2001).
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5856-5861
    • Fassbender, K.1    Simons, M.2    Bergmann, C.3    Stroick, M.4    Lutjohann, D.5    Keller, P.6
  • 21
    • 0037227538 scopus 로고    scopus 로고
    • Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism
    • Papassotiropoulos A, Streffer JR, Tsolaki M, Schmid S, Thai D, Nicosia F et al. Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism. Arch Neurol 60, 29-35 (2003).
    • (2003) Arch Neurol , vol.60 , pp. 29-35
    • Papassotiropoulos, A.1    Streffer, J.R.2    Tsolaki, M.3    Schmid, S.4    Thai, D.5    Nicosia, F.6
  • 22
    • 0034642230 scopus 로고    scopus 로고
    • Effect of APOE genotype and promoter polymorphism on risk of Alzheimer's disease
    • Wang JC, Kwon JM, Shah P, Morris JC and Goate A. Effect of APOE genotype and promoter polymorphism on risk of Alzheimer's disease. Neurology 55, 1644-1649 (2000).
    • (2000) Neurology , vol.55 , pp. 1644-1649
    • Wang, J.C.1    Kwon, J.M.2    Shah, P.3    Morris, J.C.4    Goate, A.5
  • 23
    • 0037008389 scopus 로고    scopus 로고
    • Genetic variation in the cholesterol 24-hydroxylase (CYP46) gene and the risk of Alzheimer's disease
    • Desai P, DeKosky ST and Kamboh MI. Genetic variation in the cholesterol 24-hydroxylase (CYP46) gene and the risk of Alzheimer's disease. Neurosci Lett 328, 9-12 (2002).
    • (2002) Neurosci Lett , vol.328 , pp. 9-12
    • Desai, P.1    DeKosky, S.T.2    Kamboh, M.I.3
  • 24
    • 0029038881 scopus 로고
    • Cerebral infarction in Alzheimer's disease is associated with severe amyloid angiopathy and hypertension
    • Olichney JM, Hansen LA, Hofstetter CR, Grundman M, Katzman R and Thal LJ. Cerebral infarction in Alzheimer's disease is associated with severe amyloid angiopathy and hypertension. Arch Neurol 52, 702-708 (1995).
    • (1995) Arch Neurol , vol.52 , pp. 702-708
    • Olichney, J.M.1    Hansen, L.A.2    Hofstetter, C.R.3    Grundman, M.4    Katzman, R.5    Thal, L.J.6
  • 25
    • 0033544307 scopus 로고    scopus 로고
    • APOE-491 promoter polymorphism is a risk factor for late-onset Alzheimer's disease
    • Casadei VM, Ferri C, Veglia F, Gavazzi A, Salani G, Cattaneo M et al. APOE-491 promoter polymorphism is a risk factor for late-onset Alzheimer's disease. Neurology 53, 1888-1889 (1999).
    • (1999) Neurology , vol.53 , pp. 1888-1889
    • Casadei, V.M.1    Ferri, C.2    Veglia, F.3    Gavazzi, A.4    Salani, G.5    Cattaneo, M.6
  • 26
    • 0032855024 scopus 로고    scopus 로고
    • Lack of independent associations of apolipoprotein E promoter and intron 1 polymorphisms with Alzheimer's disease
    • Rebeck GW, Cheung BS, Growdon WB, Deng A, Akuthota P, Locascio J et al. Lack of independent associations of apolipoprotein E promoter and intron 1 polymorphisms with Alzheimer's disease. Neurosci Lett 272, 155-158 (1999).
    • (1999) Neurosci Lett , vol.272 , pp. 155-158
    • Rebeck, G.W.1    Cheung, B.S.2    Growdon, W.B.3    Deng, A.4    Akuthota, P.5    Locascio, J.6
  • 27
    • 0037465449 scopus 로고    scopus 로고
    • CSF Abeta42 levels correlate with amyloid-neuropathology in a population-based autopsy study
    • Strozyk D, Blennow K, White LR and Launer LJ. CSF Abeta42 levels correlate with amyloid-neuropathology in a population-based autopsy study. Neurology 60, 652-656 (2003).
    • (2003) Neurology , vol.60 , pp. 652-656
    • Strozyk, D.1    Blennow, K.2    White, L.R.3    Launer, L.J.4


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