-
1
-
-
0034509668
-
Genetic factors in the genesis of Alzheimer's disease
-
St George-Hyslop PH. Genetic factors in the genesis of Alzheimer's disease. Ann NY Acad Sci 924, 1-7 (2000).
-
(2000)
Ann NY Acad Sci
, vol.924
, pp. 1-7
-
-
St. George-Hyslop, P.H.1
-
2
-
-
0031918785
-
The genetics of Alzheimer disease: Current status and future prospects
-
Blacker D and Tanzi RE. The genetics of Alzheimer disease: current status and future prospects. Arch Neurol 55, 294-296 (1998).
-
(1998)
Arch Neurol
, vol.55
, pp. 294-296
-
-
Blacker, D.1
Tanzi, R.E.2
-
3
-
-
0035910317
-
Genetic susceptibility factors for Alzheimer's disease
-
Richard F and Amouyel P. Genetic susceptibility factors for Alzheimer's disease. Eur J Pharmacol 412, 1-12 (2001).
-
(2001)
Eur J Pharmacol
, vol.412
, pp. 1-12
-
-
Richard, F.1
Amouyel, P.2
-
4
-
-
0038509216
-
APOE ε4 favours cerebrovascular over parenchymal deposition of Aβ protein and thereby influences the pathological phenotype of ε4-associated Alzheimer's disease
-
Chalmers KA, Wilcock GK and Love S. APOE ε4 favours cerebrovascular over parenchymal deposition of Aβ protein and thereby influences the pathological phenotype of ε4-associated Alzheimer's disease. Neuropathol Appl Neurobiol 29, 231-238 (2003).
-
(2003)
Neuropathol Appl Neurobiol
, vol.29
, pp. 231-238
-
-
Chalmers, K.A.1
Wilcock, G.K.2
Love, S.3
-
5
-
-
17344374322
-
A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia
-
Bullido MJ, Artiga MJ, Recuero M, Sastre I, Garcia MA, Aldudo J et al. A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia. Nature Genet 18, 69-71 (1998).
-
(1998)
Nature Genet
, vol.18
, pp. 69-71
-
-
Bullido, M.J.1
Artiga, M.J.2
Recuero, M.3
Sastre, I.4
Garcia, M.A.5
Aldudo, J.6
-
6
-
-
0031911596
-
A new polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease
-
Lambert JC, Pasquier F, Cottel D, Frigard B, Amouyel P and Chartier-Harlin MC. A new polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease. Hum Mol Genet 7, 533-540 (1998).
-
(1998)
Hum Mol Genet
, vol.7
, pp. 533-540
-
-
Lambert, J.C.1
Pasquier, F.2
Cottel, D.3
Frigard, B.4
Amouyel, P.5
Chartier-Harlin, M.C.6
-
7
-
-
0037345672
-
Expanding the association between the APOE gene and the risk of Alzheimer's disease: Possible roles for APOE promoter polymorphisms and alterations in APOE transcription
-
Laws SM, Hone E, Gandy SE and Martins RN. Expanding the association between the APOE gene and the risk of Alzheimer's disease: possible roles for APOE promoter polymorphisms and alterations in APOE transcription. J Neurochem 84, 1215-1236 (2003).
-
(2003)
J Neurochem
, vol.84
, pp. 1215-1236
-
-
Laws, S.M.1
Hone, E.2
Gandy, S.E.3
Martins, R.N.4
-
8
-
-
0032498118
-
Allelic polymorphisms in the transcriptional regulatory region of apolipoprotein E gene
-
Artiga MJ, Bullido MJ, Sastre I, Recuero M, Garcia MA, Aldudo J et al. Allelic polymorphisms in the transcriptional regulatory region of apolipoprotein E gene. FEBS Lett 421, 105-108 (1998).
-
(1998)
FEBS Lett
, vol.421
, pp. 105-108
-
-
Artiga, M.J.1
Bullido, M.J.2
Sastre, I.3
Recuero, M.4
Garcia, M.A.5
Aldudo, J.6
-
9
-
-
0033577180
-
The -491AA polymorphism in the APOE gene is associated with increased plasma apoE levels in Alzheimer's disease
-
Laws SM, Taddei K, Martins G, Paton A, Fisher C, Clarnette R et al. The -491AA polymorphism in the APOE gene is associated with increased plasma apoE levels in Alzheimer's disease. Neuroreport 10, 879-882 (1999).
-
(1999)
Neuroreport
, vol.10
, pp. 879-882
-
-
Laws, S.M.1
Taddei, K.2
Martins, G.3
Paton, A.4
Fisher, C.5
Clarnette, R.6
-
10
-
-
85101728623
-
Effect of the APOE promoter polymorphisms on cerebral amyloid peptide deposition in Alzheimer's disease (erratum appears in Lancet 2001 Apr 28;357(9265):1370)
-
Lambert JC, Mann D, Goumidi L, Harris J, Amouyel P, Iwatsubo T et al. Effect of the APOE promoter polymorphisms on cerebral amyloid peptide deposition in Alzheimer's disease (erratum appears in Lancet 2001 Apr 28;357(9265):1370). Lancet 357, 608-619 (2001).
-
(2001)
Lancet
, vol.357
, pp. 608-619
-
-
Lambert, J.C.1
Mann, D.2
Goumidi, L.3
Harris, J.4
Amouyel, P.5
Iwatsubo, T.6
-
11
-
-
7344221464
-
Pronounced impact of Th1/E47cs mutation compared with -491 at mutation on neural APOE gene expression and risk of developing Alzheimer's disease
-
Lambert JC, Berr C, Pasquier F, Delacourte A, Frigard B, Cottel D et al. Pronounced impact of Th1/E47cs mutation compared with -491 AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease. Hum Mol Genet 7, 1511-1516 (1998).
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1511-1516
-
-
Lambert, J.C.1
Berr, C.2
Pasquier, F.3
Delacourte, A.4
Frigard, B.5
Cottel, D.6
-
12
-
-
0037047008
-
Contribution of APOE promoter polymorphisms to Alzheimer's disease risk
-
Lambert JC, Araria-Goumidi L, Myllykangas L, Ellis C, Wang JC, Bullido MJ et al. Contribution of APOE promoter polymorphisms to Alzheimer's disease risk. Neurology 59, 59-66 (2002).
-
(2002)
Neurology
, vol.59
, pp. 59-66
-
-
Lambert, J.C.1
Araria-Goumidi, L.2
Myllykangas, L.3
Ellis, C.4
Wang, J.C.5
Bullido, M.J.6
-
13
-
-
0032545164
-
The -491 A/T polymorphism in the regulatory region of the apolipoprotein e gene and early-onset Alzheimer's disease
-
Roks G, Cruts M, Bullido MJ, Backhovens H, Artiga MJ, Hofman A et al. The -491 A/T polymorphism in the regulatory region of the apolipoprotein E gene and early-onset Alzheimer's disease. Neurosci Lett 258, 65-68 (1998).
-
(1998)
Neurosci Lett
, vol.258
, pp. 65-68
-
-
Roks, G.1
Cruts, M.2
Bullido, M.J.3
Backhovens, H.4
Artiga, M.J.5
Hofman, A.6
-
14
-
-
0032503943
-
Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE
-
Song YQ, Rogaeva E, Premkumar S, Brindle N, Kawarai T, Orlacchio A et al. Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE. Neurosci Lett 250, 189-192 (1998).
-
(1998)
Neurosci Lett
, vol.250
, pp. 189-192
-
-
Song, Y.Q.1
Rogaeva, E.2
Premkumar, S.3
Brindle, N.4
Kawarai, T.5
Orlacchio, A.6
-
15
-
-
0032924870
-
Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease
-
Kehoe PG, Russ C, McIlory S, Williams H, Holmans P, Holmes C et al. Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. Nature Genet 21, 71-72 (1999).
-
(1999)
Nature Genet
, vol.21
, pp. 71-72
-
-
Kehoe, P.G.1
Russ, C.2
McIlory, S.3
Williams, H.4
Holmans, P.5
Holmes, C.6
-
16
-
-
0242600651
-
Haplotypes extending across ACE are associated with Alzheimer's disease
-
Kehoe PG, Katzov H, Feuk L, Bennet AM, Johansson B, Wiman B et al. Haplotypes extending across ACE are associated with Alzheimer's disease. Hum Mol Genet 12, 1-9 (2003).
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1-9
-
-
Kehoe, P.G.1
Katzov, H.2
Feuk, L.3
Bennet, A.M.4
Johansson, B.5
Wiman, B.6
-
17
-
-
0035930538
-
Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta); retards a beta aggregation, deposition, fibril formation; and inhibits cytotoxicity
-
Hu J, Igarashi A, Kamata M and Nakagawa H. Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta); retards A beta aggregation, deposition, fibril formation; and inhibits cytotoxicity. J Biol Chem 276, 47863-47868 (2001).
-
(2001)
J Biol Chem
, vol.276
, pp. 47863-47868
-
-
Hu, J.1
Igarashi, A.2
Kamata, M.3
Nakagawa, H.4
-
18
-
-
0037119213
-
The angiotensin 1-converting enzyme insertion (I)/deletion (D) polymorphism does not influence the extent of amyloid or tau pathology in patients with sporadic Alzheimer's disease
-
Lendon CL, Thaker U, Harris JM, McDonagh AM, Lambert JC, Chartier-Harlin MC et al. The angiotensin 1-converting enzyme insertion (I)/deletion (D) polymorphism does not influence the extent of amyloid or tau pathology in patients with sporadic Alzheimer's disease. Neurosci Lett 328, 314-318 (2002).
-
(2002)
Neurosci Lett
, vol.328
, pp. 314-318
-
-
Lendon, C.L.1
Thaker, U.2
Harris, J.M.3
McDonagh, A.M.4
Lambert, J.C.5
Chartier-Harlin, M.C.6
-
19
-
-
0033772113
-
Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme a reductase inhibitors
-
Wolozin B, Kellman W, Ruosseau P, Celesia GG and Siegel G. Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Arch Neurol 57, 1439-1443 (2000).
-
(2000)
Arch Neurol
, vol.57
, pp. 1439-1443
-
-
Wolozin, B.1
Kellman, W.2
Ruosseau, P.3
Celesia, G.G.4
Siegel, G.5
-
20
-
-
0001504829
-
Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides A beta 42 and A beta 40 in vitro and in vivo
-
Fassbender K, Simons M, Bergmann C, Stroick M, Lutjohann D, Keller P et al. Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides A beta 42 and A beta 40 in vitro and in vivo. Proc Natl Acad Sci USA 98, 5856-5861 (2001).
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5856-5861
-
-
Fassbender, K.1
Simons, M.2
Bergmann, C.3
Stroick, M.4
Lutjohann, D.5
Keller, P.6
-
21
-
-
0037227538
-
Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism
-
Papassotiropoulos A, Streffer JR, Tsolaki M, Schmid S, Thai D, Nicosia F et al. Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism. Arch Neurol 60, 29-35 (2003).
-
(2003)
Arch Neurol
, vol.60
, pp. 29-35
-
-
Papassotiropoulos, A.1
Streffer, J.R.2
Tsolaki, M.3
Schmid, S.4
Thai, D.5
Nicosia, F.6
-
22
-
-
0034642230
-
Effect of APOE genotype and promoter polymorphism on risk of Alzheimer's disease
-
Wang JC, Kwon JM, Shah P, Morris JC and Goate A. Effect of APOE genotype and promoter polymorphism on risk of Alzheimer's disease. Neurology 55, 1644-1649 (2000).
-
(2000)
Neurology
, vol.55
, pp. 1644-1649
-
-
Wang, J.C.1
Kwon, J.M.2
Shah, P.3
Morris, J.C.4
Goate, A.5
-
23
-
-
0037008389
-
Genetic variation in the cholesterol 24-hydroxylase (CYP46) gene and the risk of Alzheimer's disease
-
Desai P, DeKosky ST and Kamboh MI. Genetic variation in the cholesterol 24-hydroxylase (CYP46) gene and the risk of Alzheimer's disease. Neurosci Lett 328, 9-12 (2002).
-
(2002)
Neurosci Lett
, vol.328
, pp. 9-12
-
-
Desai, P.1
DeKosky, S.T.2
Kamboh, M.I.3
-
24
-
-
0029038881
-
Cerebral infarction in Alzheimer's disease is associated with severe amyloid angiopathy and hypertension
-
Olichney JM, Hansen LA, Hofstetter CR, Grundman M, Katzman R and Thal LJ. Cerebral infarction in Alzheimer's disease is associated with severe amyloid angiopathy and hypertension. Arch Neurol 52, 702-708 (1995).
-
(1995)
Arch Neurol
, vol.52
, pp. 702-708
-
-
Olichney, J.M.1
Hansen, L.A.2
Hofstetter, C.R.3
Grundman, M.4
Katzman, R.5
Thal, L.J.6
-
25
-
-
0033544307
-
APOE-491 promoter polymorphism is a risk factor for late-onset Alzheimer's disease
-
Casadei VM, Ferri C, Veglia F, Gavazzi A, Salani G, Cattaneo M et al. APOE-491 promoter polymorphism is a risk factor for late-onset Alzheimer's disease. Neurology 53, 1888-1889 (1999).
-
(1999)
Neurology
, vol.53
, pp. 1888-1889
-
-
Casadei, V.M.1
Ferri, C.2
Veglia, F.3
Gavazzi, A.4
Salani, G.5
Cattaneo, M.6
-
26
-
-
0032855024
-
Lack of independent associations of apolipoprotein E promoter and intron 1 polymorphisms with Alzheimer's disease
-
Rebeck GW, Cheung BS, Growdon WB, Deng A, Akuthota P, Locascio J et al. Lack of independent associations of apolipoprotein E promoter and intron 1 polymorphisms with Alzheimer's disease. Neurosci Lett 272, 155-158 (1999).
-
(1999)
Neurosci Lett
, vol.272
, pp. 155-158
-
-
Rebeck, G.W.1
Cheung, B.S.2
Growdon, W.B.3
Deng, A.4
Akuthota, P.5
Locascio, J.6
-
27
-
-
0037465449
-
CSF Abeta42 levels correlate with amyloid-neuropathology in a population-based autopsy study
-
Strozyk D, Blennow K, White LR and Launer LJ. CSF Abeta42 levels correlate with amyloid-neuropathology in a population-based autopsy study. Neurology 60, 652-656 (2003).
-
(2003)
Neurology
, vol.60
, pp. 652-656
-
-
Strozyk, D.1
Blennow, K.2
White, L.R.3
Launer, L.J.4
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