SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk

Annals of Neurology

Volumn 69, Issue 1, 2011, Pages 47-64

  Reitz, Christiane ^a,b,c   Tokuhiro, Shinya ^e   Clark, Lorraine N ^a,c   Conrad, Christopher ^a,c   Vonsattel, Jean Paul ^a,c   Hazrati, Lili Naz ^e   Palotás, András ^m   Lantigua, Raphael ^a,d   Medrano, Martin ^k   Jiménez Velázquez, Ivonne Z ^l   Vardarajan, Badri ^g   Simkin, Irene ^g   Haines, Jonathan L ^h   Pericak Vance, Margaret A ⁱ   Farrer, Lindsay A ^g   Lee, Joseph H ^a,b,c   Rogaeva, Ekaterina ^e   St George Hyslop, Peter ^e,f,j   Mayeux, Richard ^a,b,c,d  

^a NewYork Presbyterian Hospital   (United States)

^b Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d Boston University Schools of Medicine and Public Health ^*  (United States)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY HEALTH NETWORK   (Canada)

^g BOSTON UNIVERSITY   (United States)

^h VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^j UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^k UNIVERSIDAD TECNOLÓGICA DE SANTIAGO   (Dominican Republic)

^l UNIVERSITY OF PUERTO RICO SCHOOL OF MEDICINE   (Puerto Rico)

^m Asklepios Med Bt   (Hungary)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; GAMMA SECRETASE; SORTILIN; SORTILIN RELATED VPS10 DOMAIN CONTAINING RECEPTOR 1; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; FEMALE; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN SYNTHESIS INHIBITION; PROTEIN VARIANT; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; BRAIN; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE EXPRESSION; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPE; HUMANS; LDL-RECEPTOR RELATED PROTEINS; MEMBRANE TRANSPORT PROTEINS; META-ANALYSIS AS TOPIC; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, CELL SURFACE; RISK FACTORS;

EID: 79551474326     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.22308     Document Type: Article

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