ABCA1 polymorphisms and Alzheimer's disease

Neuroscience Letters

Volumn 416, Issue 2, 2007, Pages 180-183

  Wavrant De Vrièze, Fabienne ^a   Compton, Danielle ^a   Womick, Meridith ^a   Arepalli, Sampath ^a   Adighibe, Omanma ^a   Li, Ling ^b   Pérez Tur, Jordi ^c   Hardy, John ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b and Clinical Center   (United States)

^c INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

Author keywords

ABCA1; Alzheimer's disease; Polymorphisms

Indexed keywords

ABC TRANSPORTER A1; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E;

ABCA1 GENE; AGED; ALZHEIMER DISEASE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHROMOSOME 9; FEMALE; GENE; GENE MAPPING; GENETIC LINKAGE; GENOTYPE; GERIATRIC PATIENT; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; NUCLEOTIDE SEQUENCE; ONSET AGE; PEDIGREE ANALYSIS; PRIORITY JOURNAL; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SIBLING; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; ALZHEIMER DISEASE; ATP-BINDING CASSETTE TRANSPORTERS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; PEDIGREE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RISK FACTORS;

EID: 33947329031     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.02.010     Document Type: Article

References (26)

1. Blacker D., Bertram L., Saunders A.J., Moscarillo T.J., Albert M.S., Wiener H., Perry R.T., Collins J.S., Harrell L.E., Go R.C., Mahoney A., Beaty T., Fallin M.D., Avramopoulos D., Chase G.A., Folstein M.F., McInnis M.G., Bassett S.S., Doheny K.J., Pugh E.W., and Tanzi R.E. Results of a high-resolution genome screen of 437 Alzheimer's disease families. Hum. Mol. Genet. 12 (2003) 23-32
2. Bodzioch M., Orso E., Klucken J., Langmann T., Bottcher A., Diederich W., Drobnik W., Barlage S., Buchler C., Porsch-Ozcurumez M., Kaminski W.E., Hahmann H.W., Oette K., Rothe G., Aslanidis C., Lackner K.J., and Schmitz G. The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease. Nat. Genet. 22 (1999) 347-351
3. Brooks-Wilson A., Marcil M., Clee S.M., Zhang L.H., Roomp K., van Dam M., Yu L., Brewer C., Collins J.A., Molhuizen H.O., Loubser O., Ouelette B.F., Fichter K., Ashbourne-Excoffon K.J., Sensen C.W., Scherer S., Mott S., Denis M., Martindale D., Frohlich J., Morgan K., Koop B., Pimstone S., Kastelein J.J., Genest Jr. J., and Hayden M.R. Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nat. Genet. 22 (1999) 336-345
4. Burns M., and Duff K. Use of in vivo models to study the role of cholesterol in the etiology of Alzheimer's disease. Neurochem. Res. 28 (2003) 979-986
5. Clee S.M., Zwinderman A.H., Engert J.C., Zwarts K.Y., Molhuizen H.O., Roomp K., Jukema J.W., van Wijland M., van Dam M., Hudson T.J., Brooks-Wilson A., Genest Jr. J., Kastelein J.J., and Hayden M.R. Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease. Circulation 103 (2001) 1198-1205
6. Corder E.H., Saunders A.M., Strittmatter W.J., Schmechel D.E., Gaskell P.C., Small G.W., Roses A.D., Haines J.L., and Pericak-Vance M.A. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261 (1993) 921-923
7. Frikke-Schmidt R., Nordestgaard B.G., Jensen G.B., and Tybjaerg-Hansen A. Genetic variation in ABC transporter A1 contributes to HDL cholesterol in the general population. J. Clin. Invest. 114 (2004) 1343-1353
8. Hodoglugil U., Williamson D.W., Huang Y., and Mahley R.W. Common polymorphisms of ATP binding cassette transporter A1, including a functional promoter polymorphism, associated with plasma high density lipoprotein cholesterol levels in Turks. Atherosclerosis 183 (2005) 199-212
9. Hong S.H., Rhyne J., Zeller K., and Miller M. ABCA1 (Alabama): a novel variant associated with HDL deficiency and premature coronary artery disease. Atherosclerosis 164 (2002) 245-250
10. Honig L.S., Kukull W., and Mayeux R. Atherosclerosis and AD: analysis of data from the US National Alzheimer's Coordinating Center. Neurology 64 (2005) 494-500
11. Kamboh M.I. Molecular genetics of late-onset Alzheimer's disease. Ann. Hum. Genet. 68 (2004) 381-404
12. Katzov H., Chalmers K., Palmgren J., Andreasen N., Johansson B., Cairns N.J., Gatz M., Wilcock G.K., Love S., Pedersen N.L., Brookes A.J., Blennow K., Kehoe P.G., and Prince J.A. Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism. Hum. Mutat. 23 (2004) 358-367
13. Kehoe P., Wavrant-De Vrieze F., Crook R., Wu W.S., Holmans P., Fenton I., Spurlock G., Norton N., Williams H., Williams N., Lovestone S., Perez-Tur J., Hutton M., Chartier-Harlin M.C., Shears S., Roehl K., Booth J., Van Voorst W., Ramic D., Williams J., Goate A., Hardy J., and Owen M.J. A full genome scan for late onset Alzheimer's disease. Hum. Mol. Genet. 8 (1999) 237-245
14. Koldamova R., Staufenbiel M., and Lefterov I. Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice. J. Biol. Chem. 280 (2005) 43224-43235
15. Li Y., Tacey K., Doil L., van Luchene R., Garcia V., Rowland C., Schrodi S., Leong D., Lau K., Catanese J., Sninsky J., Nowotny P., Holmans P., Hardy J., Powell J., Lovestone S., Thal L., Owen M., Williams J., Goate A., and Grupe A. Association of ABCA1 with late-onset Alzheimer's disease is not observed in a case-control study. Neurosci. Lett. 366 (2004) 268-271
16. Lutucuta S., Ballantyne C.M., Elghannam H., Gotto Jr. A.M., and Marian A.J. Novel polymorphisms in promoter region of ATP binding cassette transporter gene and plasma lipids, severity, progression, and regression of coronary atherosclerosis and response to therapy. Circ. Res. 88 (2001) 969-973
17. Myers A., Wavrant De-Vrieze F., Holmans P., Hamshere M., Crook R., Compton D., Marshall H., Meyer D., Shears S., Booth J., Ramic D., Knowles H., Morris J.C., Williams N., Norton N., Abraham R., Kehoe P., Williams H., Rudrasingham V., Rice F., Giles P., Tunstall N., Jones L., Lovestone S., Williams J., Owen M.J., Hardy J., and Goate A. Full genome screen for Alzheimer disease: stage II analysis. Am. J. Med. Genet. 114 (2002) 235-244
18. Pericak-Vance M.A., Grubber J., Bailey L.R., Hedges D., West S., Santoro L., Kemmerer B., Hall J.L., Saunders A.M., Roses A.D., Small G.W., Scott W.K., Conneally P.M., Vance J.M., and Haines J.L. Identification of novel genes in late-onset Alzheimer's disease. Exp. Gerontol. 35 (2000) 1343-1352
19. Perneger T.V. What's wrong with Bonferroni adjustments. BMJ 316 (1998) 1236-1238
20. Rothman K.J. No adjustments are needed for multiple comparisons. Epidemiology 1 (1990) 43-46
21. Rust S., Rosier M., Funke H., Real J., Amoura Z., Piette J.C., Deleuze J.F., Brewer H.B., Duverger N., Denefle P., and Assmann G. Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1. Nat. Genet. 22 (1999) 352-355
22. Shibata N., Kawarai T., Lee J.H., Lee H.S., Shibata E., Sato C., Liang Y., Duara R., Mayeux R.P., St George-Hyslop P.H., and Rogaeva E. Association studies of cholesterol metabolism genes (CH25H, ABCA1 and CH24H) in Alzheimer's disease. Neurosci. Lett. 391 (2006) 142-146
23. Souverein O.W., Jukema J.W., Boekholdt S.M., Zwinderman A.H., and Tanck M.W. Polymorphisms in APOA1 and LPL genes are statistically independently associated with fasting TG in men with CAD. Eur. J. Hum. Genet. 13 (2005) 445-451
24. Wahrle S.E., Jiang H., Parsadanian M., Hartman R.E., Bales K.R., Paul S.M., and Holtzman D.M. Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease. J. Biol. Chem. 280 (2005) 43236-43242
25. Woll P.S., Hanson N.Q., Arends V.L., and Tsai M.Y. Effect of two common polymorphisms in the ATP binding cassette transporter A1 gene on HDL-cholesterol concentration. Clin. Chem. 51 (2005) 907-909
26. Wollmer M.A., Streffer J.R., Lutjohann D., Tsolaki M., Iakovidou V., Hegi T., Pasch T., Jung H.H., Bergmann K., Nitsch R.M., Hock C., and Papassotiropoulos A. ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer's disease. Neurobiol. Aging 24 (2003) 421-426