Novel extreme homozygote haplotypes at the human caveolin 1 gene upstream purine complex in sporadic alzheimer's disease

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 153, Issue 1, 2010, Pages 347-349

  Yeganeh, M Zarif ^a   Mirabzadeh, A ^a   Khorshid, H R Khorram ^a   Kamali, K ^b   Heshmati, Y ^a   Gozalpour, E ^a   Veissy, K ^a   Nabi, M Olad ^a   Najmabadi, H ^a   Ohadi, M ^a  

^a UNIVERSITY OF SOCIAL WELFARE AND REHABILITATION SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Alzheimer's disease; Caveolin 1; Haplotype; Polymorphism; Upstream

Indexed keywords

CAVEOLIN 1; PURINE;

AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DNA FLANKING REGION; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENOTYPE; HAPLOTYPE; HOMOZYGOSITY; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

ALLELES; ALZHEIMER DISEASE; CAVEOLIN 1; HAPLOTYPES; HOMOZYGOTE; HUMANS; PURINES;

EID: 73949102879     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30985     Document Type: Article

References (8)

1. Gaudreault SB, Dea D, Poirier J. 2004. Increased caveolin-1 expression in Alzheimer's disease brain. Neurobiol aging 25:753-759.
2. Hattori C, Asai M, Onishi H, Sasagawa N, Hashimoto Y, Saido TC, Maruyama K, Mizutani S, Ishiura S. 2006. BACE1 interacts with lipid raft proteins. J Neurosci Res 84:912-917.
3. Heshmati Y, Mirabzadeh A, Feizzade G, Gilanipour M, Etminan MR, Khoram Khorshid HR, Kamali K, Fakhri M, Moghimi N, Najmabadi H, Ohadi M. 2009. A novel polymorphic purine complex at the 1.5 kb upstream region of the human caveolin-1 gene and risk of Alzheimer's disease; extra-short alleles and accumulated allele homozygosity. Am J Med Genet Part B 150B(2):248-253.
4. Ikezu T, Trapp BC, Song KS, Schlegel A, Lisanti MP, Okamoto T. 1998. Caveolae, plasma membrane microdomains for a-secretase-mediated processing of the amyloid precursor protein. J Biol Chem 273: 10485-10495.
5. Kang MJ, Chung YH, Hwang CI, Hurata M, Gujimoto T, Mook-jung IH, Cha CI, Park WY. 2006. Caveolin-1 upregulation in senescent neurons alters amyloid precursor protein processing. Exp Mol Med 38:126-133.
6. Kanno Y, Ben-zion L, Tomohiko T, Ozato K. 2005. Immune cell-specific amplification of interferon signaling by the irf-4/8-pu.1 complex. J Interferon Cytokine Res 25:770-779.
7. Musikacharoen T, Oguma A, Yoshikai Y, Chiba N, Masuda A, Matsuguchi T. 2005. Interleukin-15 induces il-12 receptor beta1 gene expression through pu.1 and irf 3 by targeting chromatin remodeling. Blood 105: 711-720.
8. Oka N, Yamamoto M, Schwencke C, Kawabe J, Ebina T, Couet J, Lisanti MP, et al. 1997. Caveolin interaction with protein kinase c: Isoenzymedependent regulation of kinase activity by the caveoli-scaffolding domain peptide. J Biol Chem 272:33416-33421.