메뉴 건너뛰기




Volumn 18, Issue 19, 2012, Pages 2734-2757

Estrogen receptor beta in cancer: An attractive target for therapy

Author keywords

Brain; Breast; Colon; ER ; Estrogen; Lung; Ovary; Prostate; Skin; Uterus; Vulva

Indexed keywords

AFIMOXIFENE; ALDOXIME; ANTIESTROGEN; ARZOXIFENE; BENZOFURAN DERIVATIVE; BENZOPYRAN DERIVATIVE; BENZOTHIOPHENE DERIVATIVE; BENZOXAZINE DERIVATIVE; BENZOXEPIN DERIVATIVE; CHROMENE DERIVATIVE; DIARYLPROPIONITRILE; DIPHENYLAMINE DERIVATIVE; ESTRADIOL DERIVATIVE; ESTROGEN; ESTROGEN RECEPTOR BETA; FURAN DERIVATIVE; IMIDAZOLE DERIVATIVE; INDAZOLE DERIVATIVE; INDENE DERIVATIVE; INDOLE DERIVATIVE; ISOCOUMARIN DERIVATIVE; LETROZOLE; PHTHALIMIDE DERIVATIVE; PYRIMIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE; RALOXIFENE; TAMOXIFEN; TETRALIN DERIVATIVE; TRIAZOLE DERIVATIVE; UNINDEXED DRUG;

EID: 84862570659     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161212800626139     Document Type: Review
Times cited : (53)

References (323)
  • 2
    • 0022887870 scopus 로고
    • Localization of the human oestrogen receptor gene to chromosome 6q24-q27 by in situ hybridization
    • Gosden JR, Middleton PG, Rout D. Localization of the human oestrogen receptor gene to chromosome 6q24-q27 by in situ hybridization. Cytogenet Cell Genet 1986; 43: 218-20.
    • (1986) Cytogenet Cell Genet , vol.43 , pp. 218-220
    • Gosden, J.R.1    Middleton, P.G.2    Rout, D.3
  • 3
    • 0030733906 scopus 로고    scopus 로고
    • Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern
    • Enmark E, Pelto-Huikko M, Grandien K, et al. Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern. J Clin Endocrinol Metab 1997; 82: 4258-65.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4258-4265
    • Enmark, E.1    Pelto-Huikko, M.2    Grandien, K.3
  • 4
    • 0001063332 scopus 로고
    • Cloning of the human estrogen receptor cDNA
    • Walter P, Green S, Greene G, et al. Cloning of the human estrogen receptor cDNA. Proc Natl Acad Sci 1985; 82: 7889-93.
    • (1985) Proc Natl Acad Sci , vol.82 , pp. 7889-7893
    • Walter, P.1    Green, S.2    Greene, G.3
  • 5
    • 0022653964 scopus 로고
    • Human oestrogen receptor cDNA: Sequence, expression and homology to v-erb-A
    • Green S, Walter P, Kumar V, et al. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature 1986; 320: 134-9.
    • (1986) Nature , vol.320 , pp. 134-139
    • Green, S.1    Walter, P.2    Kumar, V.3
  • 7
    • 0030593681 scopus 로고    scopus 로고
    • ER beta: Identification and characterization of a novel human estrogen receptor
    • Mosselman S, Polman J, Dijkema R. ER beta: identification and characterization of a novel human estrogen receptor. FEBS Lett 1996; 392: 49-53.
    • (1996) FEBS Lett , vol.392 , pp. 49-53
    • Mosselman, S.1    Polman, J.2    Dijkema, R.3
  • 8
    • 0031043390 scopus 로고    scopus 로고
    • Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta
    • Tremblay GB, Tremblay A, Copeland NG, et al. Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta. Mol Endocrinol 1997; 11: 353-65.
    • (1997) Mol Endocrinol , vol.11 , pp. 353-365
    • Tremblay, G.B.1    Tremblay, A.2    Copeland, N.G.3
  • 9
    • 0031733298 scopus 로고    scopus 로고
    • Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor b
    • Kuiper GGJM, Lemmen JG, Carlsson B, et al. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor b. Endocrinology 1998; 139: 4252-63.
    • (1998) Endocrinology , vol.139 , pp. 4252-4263
    • Kuiper, G.G.J.M.1    Lemmen, J.G.2    Carlsson, B.3
  • 10
    • 0024317270 scopus 로고
    • The human estrogen receptor has two independent nonacidic transcriptional activation functions
    • Tora L, White J, Brou C, et al. The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell. 1989; 59: 477-87.
    • (1989) Cell , vol.59 , pp. 477-487
    • Tora, L.1    White, J.2    Brou, C.3
  • 11
    • 0030771389 scopus 로고    scopus 로고
    • Human estrogen receptor beta binds DNA in a manner similar to and dimerizes with estrogen receptor alpha
    • Pace P, Taylor J, Suntharalingam S, Coombes RC, Ali S. Human estrogen receptor beta binds DNA in a manner similar to and dimerizes with estrogen receptor alpha. J Biol Chem 1997; 272: 25832-8.
    • (1997) J Biol Chem , vol.272 , pp. 25832-25838
    • Pace, P.1    Taylor, J.2    Suntharalingam, S.3    Coombes, R.C.4    Ali, S.5
  • 12
    • 0033856986 scopus 로고    scopus 로고
    • Functional differences between the amino-terminal domains of estrogen receptors alpha and beta
    • Delaunay F, Pettersson K, Tujague M, Gustafsson JA. Functional differences between the amino-terminal domains of estrogen receptors alpha and beta. Mol Pharmacol 2000; 58: 584-90.
    • (2000) Mol Pharmacol , vol.58 , pp. 584-590
    • Delaunay, F.1    Pettersson, K.2    Tujague, M.3    Gustafsson, J.A.4
  • 13
    • 0034783960 scopus 로고    scopus 로고
    • Mechanisms of estrogen action
    • Review
    • Nilsson S, Mäkelä S, Treuter E, et al. Mechanisms of estrogen action. Physiol Rev 2001; 81: 1535-65. Review.
    • (2001) Physiol Rev , vol.81 , pp. 1535-1565
    • Nilsson, S.1    Mäkelä, S.2    Treuter, E.3
  • 14
    • 0032499611 scopus 로고    scopus 로고
    • Cloning and characterization of human estrogen receptor beta isoforms
    • Moore JT, McKee DD, Slentz-Kesler K, et al. Cloning and characterization of human estrogen receptor beta isoforms. Biochem Biophys Res Commun 1998; 247: 75-8.
    • (1998) Biochem Biophys Res Commun , vol.247 , pp. 75-78
    • Moore, J.T.1    McKee, D.D.2    Slentz-Kesler, K.3
  • 15
    • 0032145924 scopus 로고    scopus 로고
    • Molecular cloning and characterization of human estrogen receptor betacx: A potential inhibitor of estrogen action in human
    • Ogawa S, Inoue S, Watanabe T, et al. Molecular cloning and characterization of human estrogen receptor betacx: a potential inhibitor of estrogen action in human. Nucleic Acids Res 1998; 26: 3505-12.
    • (1998) Nucleic Acids Res , vol.26 , pp. 3505-3512
    • Ogawa, S.1    Inoue, S.2    Watanabe, T.3
  • 16
    • 33748346434 scopus 로고    scopus 로고
    • Estrogen receptor (ER)-beta isoforms: A key to understanding ER-beta signaling
    • Leung YK, Mak P, Hassan S, Ho SM. Estrogen receptor (ER)-beta isoforms: a key to understanding ER-beta signaling. Proc Natl Acad Sci USA 2006; 103: 13162-7.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13162-13167
    • Leung, Y.K.1    Mak, P.2    Hassan, S.3    Ho, S.M.4
  • 17
    • 0027977836 scopus 로고
    • Immunohistochemical distribution of progesterone, androgen and oestrogen receptors in the human ovary during the menstrual cycle: Relationship to expression of steroid enzymes
    • Suzuki T, Sasano H, Kimura N, et al. Immunohistochemical distribution of progesterone, androgen and oestrogen receptors in the human ovary during the menstrual cycle: relationship to expression of steroid enzymes. Hum Reprod 1994; 9: 1589-95.
    • (1994) Hum Reprod , vol.9 , pp. 1589-1595
    • Suzuki, T.1    Sasano, H.2    Kimura, N.3
  • 18
    • 0033028733 scopus 로고    scopus 로고
    • Expression and localization of estrogen receptor-beta in murine and human bone
    • Vidal O, Kindblom LG and Ohlsson C. Expression and localization of estrogen receptor-beta in murine and human bone, J Bone Miner Res 1999; 14: 923-9.
    • (1999) J Bone Miner Res , vol.14 , pp. 923-929
    • Vidal, O.1    Kindblom, L.G.2    Ohlsson, C.3
  • 19
    • 0033806792 scopus 로고    scopus 로고
    • Differential expression of estrogen receptor-alpha and -beta and androgen receptor in the ovaries of marmosets and humans
    • Saunders PT, Millar MR, Williams K, et al. Differential expression of estrogen receptor-alpha and -beta and androgen receptor in the ovaries of marmosets and humans. Biol Reprod 2000; 63: 1098-105.
    • (2000) Biol Reprod , vol.63 , pp. 1098-1105
    • Saunders, P.T.1    Millar, M.R.2    Williams, K.3
  • 20
    • 0034002645 scopus 로고    scopus 로고
    • Immunolocalisation of oestrogen receptor beta in human tissues
    • Taylor AH, Al-Azzawi F. Immunolocalisation of oestrogen receptor beta in human tissues. J Mol Endocrinol 2000; 24: 145-55.
    • (2000) J Mol Endocrinol , vol.24 , pp. 145-155
    • Taylor, A.H.1    Al-Azzawi, F.2
  • 21
    • 0035186720 scopus 로고    scopus 로고
    • Site-specific regulation of oestrogen receptor-alpha and -beta by oestradiol in human adipose tissue
    • Anwar A, McTernan PG, Anderson LA, et al. Site-specific regulation of oestrogen receptor-alpha and -beta by oestradiol in human adipose tissue. Diabetes Obes Metab 2001; 3: 338-49.
    • (2001) Diabetes Obes Metab , vol.3 , pp. 338-349
    • Anwar, A.1    McTernan, P.G.2    Anderson, L.A.3
  • 23
    • 0041742207 scopus 로고    scopus 로고
    • Oestrogen receptor beta is the predominant oestrogen receptor in human scalp skin. Exp
    • Thornton MJ, Taylor AH, Mulligan K, et al. Oestrogen receptor beta is the predominant oestrogen receptor in human scalp skin. Exp. Dermatol 2003; 12: 181-90.
    • (2003) Dermatol , vol.12 , pp. 181-190
    • Thornton, M.J.1    Taylor, A.H.2    Mulligan, K.3
  • 24
    • 0042872483 scopus 로고    scopus 로고
    • The distribution of estrogen receptor beta is distinct to that of estrogen receptor alpha and the androgen receptor in human skin and the pilosebaceous unit
    • Thornton MJ, Taylor AH, Mulligan K, et al. The distribution of estrogen receptor beta is distinct to that of estrogen receptor alpha and the androgen receptor in human skin and the pilosebaceous unit. J Investig Dermatol Symp Proc 2003; 8: 100-3.
    • (2003) J Investig Dermatol Symp Proc , vol.8 , pp. 100-103
    • Thornton, M.J.1    Taylor, A.H.2    Mulligan, K.3
  • 25
    • 40749104202 scopus 로고    scopus 로고
    • Estrogen receptor beta in the brain: From form to function
    • Weiser MJ, Foradori CD, Handa RJ. Estrogen receptor beta in the brain: from form to function. Brain Res Rev 2008; 57: 309-20.
    • (2008) Brain Res Rev , vol.57 , pp. 309-320
    • Weiser, M.J.1    Foradori, C.D.2    Handa, R.J.3
  • 26
    • 0034176820 scopus 로고    scopus 로고
    • Human megakaryocytes and platelets contain the estrogen receptor beta and androgen receptor (AR): Testosterone regulates AR expression
    • Khetawat G, Faraday N, Nealen ML, et al. Human megakaryocytes and platelets contain the estrogen receptor beta and androgen receptor (AR): Testosterone regulates AR expression. Blood 2000; 95: 2289-96.
    • (2000) Blood , vol.95 , pp. 2289-2296
    • Khetawat, G.1    Faraday, N.2    Nealen, M.L.3
  • 27
    • 0842325060 scopus 로고    scopus 로고
    • Estrogen receptor-beta is the predominant estrogen receptor subtype in human oral epithelium and salivary glands
    • Välimaa H, Savolainen S, Soukka T, et al. Estrogen receptor-beta is the predominant estrogen receptor subtype in human oral epithelium and salivary glands. J Endocrinol 2004; 180: 55-62.
    • (2004) J Endocrinol , vol.180 , pp. 55-62
    • Välimaa, H.1    Savolainen, S.2    Soukka, T.3
  • 28
    • 33747466839 scopus 로고    scopus 로고
    • Structure-function relationship of estrogen receptor alpha and beta: Impact on human health
    • Ascenzi P, Bocedi A, Marino M. Structure-function relationship of estrogen receptor alpha and beta: impact on human health. Mol Aspects Med 2006; 27: 299-402.
    • (2006) Mol Aspects Med , vol.27 , pp. 299-402
    • Ascenzi, P.1    Bocedi, A.2    Marino, M.3
  • 29
    • 0033304993 scopus 로고    scopus 로고
    • The estrogen receptor beta-isoform (ER-beta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens
    • Hall JM, McDonnell DP. The estrogen receptor beta-isoform (ER-beta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens. Endocrinology 1999; 140: 5566-78.
    • (1999) Endocrinology , vol.140 , pp. 5566-5578
    • Hall, J.M.1    McDonnell, D.P.2
  • 30
    • 0034641862 scopus 로고    scopus 로고
    • Estrogen receptor beta acts as a dominant regulator of estrogen signaling
    • Pettersson K, Delaunay F, Gustafsson JA. Estrogen receptor beta acts as a dominant regulator of estrogen signaling. Oncogene 2000; 19: 4970-8.
    • (2000) Oncogene , vol.19 , pp. 4970-4978
    • Pettersson, K.1    Delaunay, F.2    Gustafsson, J.A.3
  • 31
    • 0028222533 scopus 로고
    • Down-modulation of interleukin-6 gene expression by 17 beta-estradiol in the absence of high affinity DNA binding by the estrogen receptor
    • Ray A, Prefontaine KE, Ray P. Down-modulation of interleukin-6 gene expression by 17 beta-estradiol in the absence of high affinity DNA binding by the estrogen receptor. J Biol Chem 1994; 269: 12940-6.
    • (1994) J Biol Chem , vol.269 , pp. 12940-12946
    • Ray, A.1    Prefontaine, K.E.2    Ray, P.3
  • 32
    • 0030873289 scopus 로고    scopus 로고
    • Estrogen receptor impairs interleukin-6 expression by preventing protein binding on the NF-kappaB site
    • Galien R, Garcia T. Estrogen receptor impairs interleukin-6 expression by preventing protein binding on the NF-kappaB site. Nucleic Acids Res 1997; 25: 2424-9.
    • (1997) Nucleic Acids Res , vol.25 , pp. 2424-2429
    • Galien, R.1    Garcia, T.2
  • 33
    • 0030801841 scopus 로고    scopus 로고
    • Differential ligand activation of estrogen receptors ER and ERß at AP1 sites
    • Paech K, Webb P, Kuiper GG, et al. Differential ligand activation of estrogen receptors ER and ERß at AP1 sites. Science 1997; 277: 1508-10.
    • (1997) Science , vol.277 , pp. 1508-1510
    • Paech, K.1    Webb, P.2    Kuiper, G.G.3
  • 34
    • 0030848501 scopus 로고    scopus 로고
    • Functional synergy between the transcription factor Sp1 and the estrogen receptor
    • Porter W, Saville B, Hoivik D, Safe S. Functional synergy between the transcription factor Sp1 and the estrogen receptor. Mol Endocrinol 1997; 11: 1569-80.
    • (1997) Mol Endocrinol , vol.11 , pp. 1569-1580
    • Porter, W.1    Saville, B.2    Hoivik, D.3    Safe, S.4
  • 38
    • 0028886694 scopus 로고
    • Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
    • Kato S, Endoh H, Masuhiro Y, et al. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 1995; 270: 1491-4.
    • (1995) Science , vol.270 , pp. 1491-1494
    • Kato, S.1    Endoh, H.2    Masuhiro, Y.3
  • 39
    • 0032530222 scopus 로고    scopus 로고
    • Elevated mitogen-activated protein kinase activity in estrogen-nonresponsive human breast cancer cells
    • Coutts AS, Murphy LC. Elevated mitogen-activated protein kinase activity in estrogen-nonresponsive human breast cancer cells. Cancer Res 1998; 58: 4071-4.
    • (1998) Cancer Res , vol.58 , pp. 4071-4074
    • Coutts, A.S.1    Murphy, L.C.2
  • 40
    • 0034464912 scopus 로고    scopus 로고
    • Estradiol hypersensitivity and mitogen-activated protein kinase expression in long-term estrogen deprived human breast cancer cells in vivo
    • Shim WS, Conaway M, Masamura S, et al. Estradiol hypersensitivity and mitogen-activated protein kinase expression in long-term estrogen deprived human breast cancer cells in vivo. Endocrinology 2000; 141: 396-405.
    • (2000) Endocrinology , vol.141 , pp. 396-405
    • Shim, W.S.1    Conaway, M.2    Masamura, S.3
  • 42
    • 0343247792 scopus 로고    scopus 로고
    • 17b-Estradiol regulation of human endothelial cell basal nitric oxide release, independent of cytosolic Ca2+ mobilization
    • Caulin-Glaser T, Garcia-Cardena G, Sarrel P, Sessa WC, Bender JR. 17b-Estradiol regulation of human endothelial cell basal nitric oxide release, independent of cytosolic Ca2+ mobilization. Circ Res 1997; 81: 885-92.
    • (1997) Circ Res , vol.81 , pp. 885-892
    • Caulin-Glaser, T.1    Garcia-Cardena, G.2    Sarrel, P.3    Sessa, W.C.4    Bender, J.R.5
  • 43
    • 0034802322 scopus 로고    scopus 로고
    • Cell localization, physiology, and nongenomic actions of estrogen receptors
    • Levin ER. Cell localization, physiology, and nongenomic actions of estrogen receptors. J Appl Physiol 2001; 91: 1860-7.
    • (2001) J Appl Physiol , vol.91 , pp. 1860-1867
    • Levin, E.R.1
  • 44
    • 0036224417 scopus 로고    scopus 로고
    • Cellular functions of plasma membrane estrogen receptors
    • Levin ER. Cellular functions of plasma membrane estrogen receptors. Steroids 2002; 67: 471-5.
    • (2002) Steroids , vol.67 , pp. 471-475
    • Levin, E.R.1
  • 45
    • 0037462733 scopus 로고    scopus 로고
    • Proximal events in signaling by plasma membrane estrogen receptors
    • Razandi M, Pedram A, Park ST, Levin ER. Proximal events in signaling by plasma membrane estrogen receptors. J Biol Chem 2003; 278: 2701-12.
    • (2003) J Biol Chem , vol.278 , pp. 2701-2712
    • Razandi, M.1    Pedram, A.2    Park, S.T.3    Levin, E.R.4
  • 46
    • 0001548401 scopus 로고    scopus 로고
    • Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: Studies of ERa and ERb expressed in Chinese hamster ovary cells
    • Razandi M, Pedram A, Greene GL, Levin ER. Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERa and ERb expressed in Chinese hamster ovary cells. Mol Endocrinol 1999; 13: 307-19.
    • (1999) Mol Endocrinol , vol.13 , pp. 307-319
    • Razandi, M.1    Pedram, A.2    Greene, G.L.3    Levin, E.R.4
  • 47
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
    • Simoncini T, Hafezi-Moghadam A, Brazil DP, Ley K, Chin WW, Liao JK. Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 2000; 407; 538-41.
    • (2000) Nature , vol.407 , pp. 538-541
    • Simoncini, T.1    Hafezi-Moghadam, A.2    Brazil, D.P.3    Ley, K.4    Chin, W.W.5    Liao, J.K.6
  • 48
    • 0036813660 scopus 로고    scopus 로고
    • ER-X: A novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury
    • Toran-Allerand CD, Guan X, MacLusky NJ, et al. ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury. J Neurosci 2002; 22: 8391-401.
    • (2002) J Neurosci , vol.22 , pp. 8391-8401
    • Toran-Allerand, C.D.1    Guan, X.2    Maclusky, N.J.3
  • 49
    • 0037446887 scopus 로고    scopus 로고
    • Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells
    • Li L, Haynes MP, Bender JR. Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells. Proc Natl Acad Sci USA 2003; 100: 4807-12.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4807-4812
    • Li, L.1    Haynes, M.P.2    Bender, J.R.3
  • 50
    • 15444368857 scopus 로고    scopus 로고
    • Mechanisms of estrogen receptor signaling: Convergence of genomic and nongenomic actions on target genes
    • Review
    • Björnström L, Sjöberg M. Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes. Mol Endocrinol 2005; 19: 833-42. Review.
    • (2005) Mol Endocrinol , vol.19 , pp. 833-842
    • Björnström, L.1    Sjöberg, M.2
  • 51
    • 0031282001 scopus 로고    scopus 로고
    • Identification of a gene (GPR30) with homology to the G-proteincoupled receptor superfamily associated with estrogen receptor expression in breast cancer
    • Carmeci C, Thompson DA, Ring HZ, Francke U, Weigel, RJ. Identification of a gene (GPR30) with homology to the G-proteincoupled receptor superfamily associated with estrogen receptor expression in breast cancer. Genomics 1997; 45: 607-17.
    • (1997) Genomics , vol.45 , pp. 607-617
    • Carmeci, C.1    Thompson, D.A.2    Ring, H.Z.3    Francke, U.4    Weigel, R.J.5
  • 53
    • 75149186664 scopus 로고    scopus 로고
    • The unfolding stories of GPR30, a new membrane-bound estrogen receptor
    • Review
    • Maggiolini M, Picard D. The unfolding stories of GPR30, a new membrane-bound estrogen receptor. J Endocrinol 2010; 204: 105-14. Review.
    • (2010) J Endocrinol , vol.204 , pp. 105-114
    • Maggiolini, M.1    Picard, D.2
  • 54
    • 0033780783 scopus 로고    scopus 로고
    • Estrogen-induced activation of Erk-1 and Erk-2 requires the G proteincoupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF
    • Filardo EJ, Quinn JA, Bland KI, Frackelton AR Jr. Estrogen-induced activation of Erk-1 and Erk-2 requires the G proteincoupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Mol Endocrinol 2000; 14: 1649-60.
    • (2000) Mol Endocrinol , vol.14 , pp. 1649-1660
    • Filardo, E.J.1    Quinn, J.A.2    Bland, K.I.3    Frackelton Jr., A.R.4
  • 55
    • 0036140032 scopus 로고    scopus 로고
    • Estrogen action via the G protein-coupled receptor, GPR30: Stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis
    • Filardo EJ, Quinn JA, Frackelton AR Jr, Bland KI. Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Mol Endocrinol 2002; 16: 70-84.
    • (2002) Mol Endocrinol , vol.16 , pp. 70-84
    • Filardo, E.J.1    Quinn, J.A.2    Frackelton Jr., A.R.3    Bland, K.I.4
  • 56
    • 0345732757 scopus 로고    scopus 로고
    • 17beta-estradiol inhibits oxidative stressinduced apoptosis in keratinocytes by promoting Bcl-2 expression
    • Kanda N, Watanabe S. 17beta-estradiol inhibits oxidative stressinduced apoptosis in keratinocytes by promoting Bcl-2 expression. J Invest Dermatol 2003; 121: 1500-9.
    • (2003) J Invest Dermatol , vol.121 , pp. 1500-1509
    • Kanda, N.1    Watanabe, S.2
  • 57
    • 3242684951 scopus 로고    scopus 로고
    • 17beta-estradiol stimulates the growth of human keratinocytes by inducing cyclin D2 expression
    • Kanda N, Watanabe S. 17beta-estradiol stimulates the growth of human keratinocytes by inducing cyclin D2 expression. J Invest Dermatol 2004; 123: 319-28.
    • (2004) J Invest Dermatol , vol.123 , pp. 319-328
    • Kanda, N.1    Watanabe, S.2
  • 58
    • 33748923143 scopus 로고    scopus 로고
    • 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30
    • Vivacqua A, Bonofiglio D, Albanito L, et al. 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30. Mol Pharmacol 2006; 70: 1414-23.
    • (2006) Mol Pharmacol , vol.70 , pp. 1414-1423
    • Vivacqua, A.1    Bonofiglio, D.2    Albanito, L.3
  • 59
    • 33344461590 scopus 로고    scopus 로고
    • The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells
    • Vivacqua A, Bonofiglio D, Recchia AG, et al. The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells. Mol Endocrinol 2006; 20: 631-46.
    • (2006) Mol Endocrinol , vol.20 , pp. 631-646
    • Vivacqua, A.1    Bonofiglio, D.2    Recchia, A.G.3
  • 60
    • 33847755409 scopus 로고    scopus 로고
    • G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells
    • Albanito L, Madeo A, Lappano R, et al. G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells. Cancer Res 2007; 67: 1859-66.
    • (2007) Cancer Res , vol.67 , pp. 1859-1866
    • Albanito, L.1    Madeo, A.2    Lappano, R.3
  • 62
    • 70449434786 scopus 로고    scopus 로고
    • Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha
    • Collins F, MacPherson S, Brown P, et al. Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha. BMC Cancer 2009; Sep 16; 9: 330.
    • (2009) BMC Cancer , vol.9 , pp. 330
    • Collins, F.1    Macpherson, S.2    Brown, P.3
  • 63
    • 67849116210 scopus 로고    scopus 로고
    • IARC. Combined estrogen-progestogen contraceptives and combined estrogen-progestogen menopausal therapy, Lyon: International Agency for Research on Cancer
    • IARC. Combined estrogen-progestogen contraceptives and combined estrogen-progestogen menopausal therapy. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Lyon: International Agency for Research on Cancer; 2007
    • (2007) IARC Monographs On the Evaluation of Carcinogenic Risks to Humans
  • 64
    • 40449137062 scopus 로고    scopus 로고
    • Postmenopausal hormone therapy and the risk of breast cancer: A contrary thought
    • Review
    • Speroff L. Postmenopausal hormone therapy and the risk of breast cancer: a contrary thought. Menopause 2008; 15: 393-400. Review.
    • (2008) Menopause , vol.15 , pp. 393-400
    • Speroff, L.1
  • 65
    • 76349096691 scopus 로고    scopus 로고
    • Hormone replacement therapy (HRT), breast cancer and tumor pathology
    • Review
    • Dietel M. Hormone replacement therapy (HRT), breast cancer and tumor pathology. Maturitas 2010; 65: 183-9. Review.
    • (2010) Maturitas , vol.65 , pp. 183-189
    • Dietel, M.1
  • 66
    • 77953356268 scopus 로고    scopus 로고
    • The rise and fall in menopausal hormone therapy and breast cancer incidence
    • Pelucchi C, Levi F, La Vecchia C. The rise and fall in menopausal hormone therapy and breast cancer incidence. Breast 2010; 19: 198-201.
    • (2010) Breast , vol.19 , pp. 198-201
    • Pelucchi, C.1    Levi, F.2    la Vecchia, C.3
  • 67
    • 0033657888 scopus 로고    scopus 로고
    • Tissue-specific synthesis and oxidative metabolism of estrogens. In: Estrogens as endogenous carcinogens in the breast and prostate
    • No. 27. Bethesda, Md.: National Cancer Institute, July
    • Jefcoate CR, Liehr JG, Santen RJ, et al. Tissue-specific synthesis and oxidative metabolism of estrogens. In: Estrogens as endogenous carcinogens in the breast and prostate. Journal of the National Cancer Institute monograph. No. 27. Bethesda, Md.: National Cancer Institute, July 2000: 95-112.
    • (2000) Journal of the National Cancer Institute Monograph , pp. 95-112
    • Jefcoate, C.R.1    Liehr, J.G.2    Santen, R.J.3
  • 68
    • 30944469849 scopus 로고    scopus 로고
    • Estrogen carcinogenesis in breast cancer
    • Yager JD, Davidson NE. Estrogen carcinogenesis in breast cancer. N Engl J Med 2006; 354: 270-82.
    • (2006) N Engl J Med , vol.354 , pp. 270-282
    • Yager, J.D.1    Davidson, N.E.2
  • 69
    • 0037208632 scopus 로고    scopus 로고
    • Incidence of invasive breast cancer by hormone receptor status from 1992 to 1998
    • Li CI, Daling JR, Malone KE. Incidence of invasive breast cancer by hormone receptor status from 1992 to 1998. J Clin Oncol 2003; 21: 28-34.
    • (2003) J Clin Oncol , vol.21 , pp. 28-34
    • Li, C.I.1    Daling, J.R.2    Malone, K.E.3
  • 70
    • 0032569831 scopus 로고    scopus 로고
    • Tamoxifen in the treatment of breast cancer
    • Osborne CK. Tamoxifen in the treatment of breast cancer. N Engl J Med 1998; 339: 1609-18.
    • (1998) N Engl J Med , vol.339 , pp. 1609-1618
    • Osborne, C.K.1
  • 71
    • 3242796665 scopus 로고    scopus 로고
    • Current status of aromatase inhibitors in the management of breast cancer and critique of the NCIC MA-17 trial
    • Baum M. Current status of aromatase inhibitors in the management of breast cancer and critique of the NCIC MA-17 trial. Cancer Control 2004; 11: 217-21.
    • (2004) Cancer Control , vol.11 , pp. 217-221
    • Baum, M.1
  • 72
    • 28744458215 scopus 로고    scopus 로고
    • Clinical significance of estrogen receptor beta in breast cancer
    • Saji S, Hirose M, Toi M. Clinical significance of estrogen receptor beta in breast cancer. Cancer Chemother Pharmacol. 2005; 56; Suppl 1: 21-6.
    • (2005) Cancer Chemother Pharmacol , vol.56 , Issue.1 , pp. 21-26
    • Saji, S.1    Hirose, M.2    Toi, M.3
  • 73
    • 33745111199 scopus 로고    scopus 로고
    • Is oestrogen receptor-beta a predictor of endocrine therapy responsiveness in human breast cancer?
    • Murphy LC, Watson PH. Is oestrogen receptor-beta a predictor of endocrine therapy responsiveness in human breast cancer? Endocr Relat Cancer 2006; 13: 327-34.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 327-334
    • Murphy, L.C.1    Watson, P.H.2
  • 74
    • 1642535535 scopus 로고    scopus 로고
    • Estrogen receptor inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest
    • Paruthiyil S, Parmar H, Kerekatte V, Cunha GR, Firestone GL, Leitman DC. Estrogen receptor inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest. Cancer Res 2004; 64: 423-8.
    • (2004) Cancer Res , vol.64 , pp. 423-428
    • Paruthiyil, S.1    Parmar, H.2    Kerekatte, V.3    Cunha, G.R.4    Firestone, G.L.5    Leitman, D.C.6
  • 75
    • 1242300083 scopus 로고    scopus 로고
    • Estrogen receptor inhibits 17 -estradiol-stimulated proliferation of the breast cancer cell line T47D
    • Strom A, Hartman J, Foster JS, et al. Estrogen receptor inhibits 17 -estradiol-stimulated proliferation of the breast cancer cell line T47D. Proc Natl Acad Sci USA 2004; 101: 1566-71.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1566-1571
    • Strom, A.1    Hartman, J.2    Foster, J.S.3
  • 76
    • 34547409238 scopus 로고    scopus 로고
    • Loss of tumourigenicity of stably ERbeta-transfected MCF-7 breast cancer cells
    • Behrens D, Gill JH, Fichtner I. Loss of tumourigenicity of stably ERbeta-transfected MCF-7 breast cancer cells. Mol Cell Endocrinol 2007; 274: 19-29.
    • (2007) Mol Cell Endocrinol , vol.274 , pp. 19-29
    • Behrens, D.1    Gill, J.H.2    Fichtner, I.3
  • 77
    • 33845762296 scopus 로고    scopus 로고
    • Estrogen receptor beta inhibits angiogenesis and growth of T47D breast cancer xenografts
    • Hartman J, Lindberg K, Morani A, Inzunza J, Ström A, Gustafsson JA. Estrogen receptor beta inhibits angiogenesis and growth of T47D breast cancer xenografts. Cancer Res 2006; 66: 11207-13.
    • (2006) Cancer Res , vol.66 , pp. 11207-11213
    • Hartman, J.1    Lindberg, K.2    Morani, A.3    Inzunza, J.4    Ström, A.5    Gustafsson, J.A.6
  • 78
    • 0030752456 scopus 로고    scopus 로고
    • Estrogen receptors alpha and beta form heterodimers on DNA
    • Cowley SM, Hoare S, Mosselman S, Parker MG. Estrogen receptors alpha and beta form heterodimers on DNA. J Biol Chem 1997; 272: 19858-62.
    • (1997) J Biol Chem , vol.272 , pp. 19858-19862
    • Cowley, S.M.1    Hoare, S.2    Mosselman, S.3    Parker, M.G.4
  • 79
    • 0038199515 scopus 로고    scopus 로고
    • The expression and function of estrogen receptor alpha and beta in human breast cancer and its clinical application
    • Hayashi SI, Eguchi H, Tanimoto K, et al. The expression and function of estrogen receptor alpha and beta in human breast cancer and its clinical application. Endocr Relat Cancer 2003; 10: 193-202.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 193-202
    • Hayashi, S.I.1    Eguchi, H.2    Tanimoto, K.3
  • 80
    • 0042388370 scopus 로고    scopus 로고
    • Estrogen receptor (ER) beta1 and ERbetacx/beta2 inhibit ERalpha function differently in breast cancer cell line MCF7
    • Omoto Y, Eguchi H, Yamamoto-Yamaguchi Y, Hayashi S. Estrogen receptor (ER) beta1 and ERbetacx/beta2 inhibit ERalpha function differently in breast cancer cell line MCF7. Oncogene 2003; 22: 5011-20.
    • (2003) Oncogene , vol.22 , pp. 5011-5020
    • Omoto, Y.1    Eguchi, H.2    Yamamoto-Yamaguchi, Y.3    Hayashi, S.4
  • 81
    • 46749108373 scopus 로고    scopus 로고
    • ERbeta in breast canceronlooker, passive player, or active protector?
    • Review
    • Fox EM, Davis RJ, Shupnik MA. ERbeta in breast canceronlooker, passive player, or active protector? Steroids 2008; 73: 1039-51. Review.
    • (2008) Steroids , vol.73 , pp. 1039-1051
    • Fox, E.M.1    Davis, R.J.2    Shupnik, M.A.3
  • 82
    • 38949182981 scopus 로고    scopus 로고
    • A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells
    • Williams C, Edvardsson K, Lewandowski SA, Ström A, Gustafsson JA. A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells. Oncogene 2008; 27: 1019-32.
    • (2008) Oncogene , vol.27 , pp. 1019-1032
    • Williams, C.1    Edvardsson, K.2    Lewandowski, S.A.3    Ström, A.4    Gustafsson, J.A.5
  • 83
    • 0034868904 scopus 로고    scopus 로고
    • ER beta inhibits proliferation and invasion of breast cancer cells
    • Lazennec G, Bresson D, Lucas A, Chauveau C, Vignon F. ER beta inhibits proliferation and invasion of breast cancer cells. Endocrinology 2001; 142: 4120-30.
    • (2001) Endocrinology , vol.142 , pp. 4120-4130
    • Lazennec, G.1    Bresson, D.2    Lucas, A.3    Chauveau, C.4    Vignon, F.5
  • 84
    • 0242578587 scopus 로고    scopus 로고
    • Stable transfection of an estrogen receptor beta cDNA isofrm into MDAMB231 breast cancer cells
    • Tonetti D, Rubenstein R, Deleon M, et al. Stable transfection of an estrogen receptor beta cDNA isofrm into MDAMB231 breast cancer cells. J Steroid Biochem Mol Biol 2003; 87: 47-55.
    • (2003) J Steroid Biochem Mol Biol , vol.87 , pp. 47-55
    • Tonetti, D.1    Rubenstein, R.2    Deleon, M.3
  • 85
    • 27144524273 scopus 로고    scopus 로고
    • Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11
    • Helguero LA, Faulds MH, Gustafsson JA, Haldosén LA. Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11. Oncogene 2005; 24: 6605-16.
    • (2005) Oncogene , vol.24 , pp. 6605-6616
    • Helguero, L.A.1    Faulds, M.H.2    Gustafsson, J.A.3    Haldosén, L.A.4
  • 86
    • 80052572689 scopus 로고    scopus 로고
    • Estrogen receptor causes a G2 cell cycle arrest by inhibiting CDK1 activity through the regulation of cyclin B1, GADD45A, and BTG2
    • Dec 1, Epub ahead of print
    • Paruthiyil S, Cvoro A, Tagliaferri M, Cohen I, Shtivelman E, Leitman DC. Estrogen receptor causes a G2 cell cycle arrest by inhibiting CDK1 activity through the regulation of cyclin B1, GADD45A, and BTG2. Breast Cancer Res Treat. 2010 Dec 1[Epub ahead of print]
    • (2010) Breast Cancer Res Treat
    • Paruthiyil, S.1    Cvoro, A.2    Tagliaferri, M.3    Cohen, I.4    Shtivelman, E.5    Leitman, D.C.6
  • 87
    • 17844409085 scopus 로고    scopus 로고
    • Inducible upregulation of oestrogen receptor-beta1 affects oestrogen and tamoxifen responsiveness in MCF7 human breast cancer cells
    • Murphy LC, Peng B, Lewis A, et al. Inducible upregulation of oestrogen receptor-beta1 affects oestrogen and tamoxifen responsiveness in MCF7 human breast cancer cells. J Mol Endocrinol 2005; 34: 553-66.
    • (2005) J Mol Endocrinol , vol.34 , pp. 553-566
    • Murphy, L.C.1    Peng, B.2    Lewis, A.3
  • 88
    • 43149093785 scopus 로고    scopus 로고
    • Estrogen receptor beta increases the efficacy of antiestrogens by effects on apoptosis and cell cycling in breast cancer cells
    • Hodges-Gallagher L, Valentine CD, El Bader S, Kushner PJ. Estrogen receptor beta increases the efficacy of antiestrogens by effects on apoptosis and cell cycling in breast cancer cells. Breast Cancer Res Treat 2008; 109: 241-50.
    • (2008) Breast Cancer Res Treat , vol.109 , pp. 241-250
    • Hodges-Gallagher, L.1    Valentine, C.D.2    El-Bader, S.3    Kushner, P.J.4
  • 89
    • 0023576146 scopus 로고
    • Frequency and distribution of estrogen receptor positive cells in normal, non-lactating human breast tissue
    • Petersen OW, Hoyer PE, and Van Deurs B. Frequency and distribution of estrogen receptor positive cells in normal, non-lactating human breast tissue. Cancer Res 1987; 47: 5748-51.
    • (1987) Cancer Res , vol.47 , pp. 5748-5751
    • Petersen, O.W.1    Hoyer, P.E.2    van Deurs, B.3
  • 90
    • 0030670385 scopus 로고    scopus 로고
    • Dissociation between steroid receptor expression and cell proliferation in the human breast
    • Clarke RB, Howell A, Potten CS, Anderson E. Dissociation between steroid receptor expression and cell proliferation in the human breast. Cancer Res 1997; 57: 4987-91.
    • (1997) Cancer Res , vol.57 , pp. 4987-4991
    • Clarke, R.B.1    Howell, A.2    Potten, C.S.3    Anderson, E.4
  • 91
    • 0032145441 scopus 로고    scopus 로고
    • Altered estrogen receptor alpha and beta messenger RNA expression during human breast tumorigenesis
    • Leygue E, Dotzlaw H, Watson PH, Murphy LC. Altered estrogen receptor alpha and beta messenger RNA expression during human breast tumorigenesis. Cancer Res 1998; 58: 3197-201.
    • (1998) Cancer Res , vol.58 , pp. 3197-3201
    • Leygue, E.1    Dotzlaw, H.2    Watson, P.H.3    Murphy, L.C.4
  • 92
    • 0033083820 scopus 로고    scopus 로고
    • Coexpression of estrogen receptor alpha and beta: Poor prognostic factors in human breast cancer?
    • Speirs V, Parkes AT, Kerin MJ, et al. Coexpression of estrogen receptor alpha and beta: poor prognostic factors in human breast cancer? Cancer Res 1999; 59: 525-8.
    • (1999) Cancer Res , vol.59 , pp. 525-528
    • Speirs, V.1    Parkes, A.T.2    Kerin, M.J.3
  • 93
    • 0034668114 scopus 로고    scopus 로고
    • Quantitative analysis of estrogen receptor-alpha and -beta messenger RNA expression in breast carcinoma by real-time polymerase chain reaction
    • Iwao K, Miyoshi Y, Egawa C, Ikeda N, Tsukamoto F, Noguchi S. Quantitative analysis of estrogen receptor-alpha and -beta messenger RNA expression in breast carcinoma by real-time polymerase chain reaction. Cancer 2000; 89: 1732-8.
    • (2000) Cancer , vol.89 , pp. 1732-1738
    • Iwao, K.1    Miyoshi, Y.2    Egawa, C.3    Ikeda, N.4    Tsukamoto, F.5    Noguchi, S.6
  • 94
    • 0033876197 scopus 로고    scopus 로고
    • Estrogen receptor beta is coexpressed with ERalpha and PR and associated with nodal status, grade, and proliferation rate in breast cancer
    • Järvinen TA, Pelto-Huikko M, Holli K, Isola J. Estrogen receptor beta is coexpressed with ERalpha and PR and associated with nodal status, grade, and proliferation rate in breast cancer. Am J Pathol 2000; 156: 29-35.
    • (2000) Am J Pathol , vol.156 , pp. 29-35
    • Järvinen, T.A.1    Pelto-Huikko, M.2    Holli, K.3    Isola, J.4
  • 95
    • 18244406327 scopus 로고    scopus 로고
    • Estrogen receptors and proliferation markers in primary and recurrent breast cancer
    • Jensen EV, Cheng G, Palmieri C, et al. Estrogen receptors and proliferation markers in primary and recurrent breast cancer. Proc Natl Acad Sci USA 2001; 98: 15197-202.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 15197-15202
    • Jensen, E.V.1    Cheng, G.2    Palmieri, C.3
  • 96
    • 0035122520 scopus 로고    scopus 로고
    • Estrogen receptor beta expression in invasive breast cancer
    • Mann S, Laucirica R, Carlson N, et al. Estrogen receptor beta expression in invasive breast cancer. Hum Pathol 2001; 32: 113-8.
    • (2001) Hum Pathol , vol.32 , pp. 113-118
    • Mann, S.1    Laucirica, R.2    Carlson, N.3
  • 97
    • 0035952371 scopus 로고    scopus 로고
    • Clinical value of the wild-type estrogen receptor beta expression in breast cancer
    • Omoto Y, Inoue S, Ogawa S, et al. Clinical value of the wild-type estrogen receptor beta expression in breast cancer. Cancer Lett. 2001; 163: 207-12.
    • (2001) Cancer Lett , vol.163 , pp. 207-212
    • Omoto, Y.1    Inoue, S.2    Ogawa, S.3
  • 98
    • 0035866760 scopus 로고    scopus 로고
    • Decreased expression of estrogen receptor beta protein in proliferative preinvasive mammary tumors
    • Roger P, Sahla ME, Mäkelä S, Gustafsson JA, Baldet P, Rochefort H. Decreased expression of estrogen receptor beta protein in proliferative preinvasive mammary tumors. Cancer Res 2001; 61: 2537-41.
    • (2001) Cancer Res , vol.61 , pp. 2537-2541
    • Roger, P.1    Sahla, M.E.2    Mäkelä, S.3    Gustafsson, J.A.4    Baldet, P.5    Rochefort, H.6
  • 99
    • 0037011662 scopus 로고    scopus 로고
    • Relationship of coregulator and oestrogen receptor isoform expression to de novo tamoxifen resistance in human breast cancer
    • Murphy LC, Leygue E, Niu Y, Snell L, Ho SM, Watson PH. Relationship of coregulator and oestrogen receptor isoform expression to de novo tamoxifen resistance in human breast cancer. Br J Cancer 2002; 87: 1411-6.
    • (2002) Br J Cancer , vol.87 , pp. 1411-1416
    • Murphy, L.C.1    Leygue, E.2    Niu, Y.3    Snell, L.4    Ho, S.M.5    Watson, P.H.6
  • 100
    • 0036161026 scopus 로고    scopus 로고
    • Evaluation of oestrogen receptor beta wild-type and variant protein expression, and relationship with clinicopathological factors in breast cancers
    • Omoto Y, Kobayashi S, Inoue S, Ogawa S. Evaluation of oestrogen receptor beta wild-type and variant protein expression, and relationship with clinicopathological factors in breast cancers. Eur J Cancer. 2002; 38: 380-6.
    • (2002) Eur J Cancer , vol.38 , pp. 380-386
    • Omoto, Y.1    Kobayashi, S.2    Inoue, S.3    Ogawa, S.4
  • 101
    • 0042326176 scopus 로고    scopus 로고
    • Clinical significance of the expression of estrogen receptors alpha and beta for endocrine therapy of breast cancer
    • Iwase H, Zhang Z, Omoto Y, et al. Clinical significance of the expression of estrogen receptors alpha and beta for endocrine therapy of breast cancer. Cancer Chemother Pharmacol 2003; 52: S34-8.
    • (2003) Cancer Chemother Pharmacol , vol.52 , pp. 34-38
    • Iwase, H.1    Zhang, Z.2    Omoto, Y.3
  • 102
    • 0038160964 scopus 로고    scopus 로고
    • Expression of estrogen receptor-beta in normal mammary and tumor tissues: Is it protective in breast carcinogenesis?
    • Park BW, Kim KS, Heo MK, et al. Expression of estrogen receptor-beta in normal mammary and tumor tissues: is it protective in breast carcinogenesis? Breast Cancer Res Treat 2003; 80: 79-85.
    • (2003) Breast Cancer Res Treat , vol.80 , pp. 79-85
    • Park, B.W.1    Kim, K.S.2    Heo, M.K.3
  • 103
    • 0141995803 scopus 로고    scopus 로고
    • Reduced expression of oestrogen receptor beta in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model
    • Skliris GP, Munot K, Bell SM, et al. Reduced expression of oestrogen receptor beta in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model. J Pathol 2003; 201: 213-20.
    • (2003) J Pathol , vol.201 , pp. 213-220
    • Skliris, G.P.1    Munot, K.2    Bell, S.M.3
  • 104
    • 4444254432 scopus 로고    scopus 로고
    • Estrogen receptor beta (ER beta) level but not its ER beta cx variant helps to predict tamoxifen resistance in breast cancer
    • Esslimani-Sahla M, Simony-Lafontaine J, Kramar A, et al. Estrogen receptor beta (ER beta) level but not its ER beta cx variant helps to predict tamoxifen resistance in breast cancer. Clin Cancer Res 2004; 10: 5769-76.
    • (2004) Clin Cancer Res , vol.10 , pp. 5769-5776
    • Esslimani-Sahla, M.1    Simony-Lafontaine, J.2    Kramar, A.3
  • 105
    • 9344264630 scopus 로고    scopus 로고
    • Low levels of estrogen receptor beta protein predict resistance to tamoxifen therapy in breast cancer
    • Hopp TA, Weiss HL, Parra IS, Cui Y, Osborne CK, Fuqua SA. Low levels of estrogen receptor beta protein predict resistance to tamoxifen therapy in breast cancer. Clin Cancer Res 2004; 10: 7490-9.
    • (2004) Clin Cancer Res , vol.10 , pp. 7490-7499
    • Hopp, T.A.1    Weiss, H.L.2    Parra, I.S.3    Cui, Y.4    Osborne, C.K.5    Fuqua, S.A.6
  • 106
    • 2442553813 scopus 로고    scopus 로고
    • The favourable prognostic value of oestrogen receptor beta immunohisto-chemical expression in breast cancer
    • Nakopoulou L, Lazaris AC, Panayotopoulou EG, et al. The favourable prognostic value of oestrogen receptor beta immunohisto-chemical expression in breast cancer. J Clin Pathol 2004; 57: 523-8.
    • (2004) J Clin Pathol , vol.57 , pp. 523-528
    • Nakopoulou, L.1    Lazaris, A.C.2    Panayotopoulou, E.G.3
  • 107
    • 9144226888 scopus 로고    scopus 로고
    • Wild-type oestrogen receptor beta (ERbeta1) mRNA and protein expression in Tamoxifen-treated post-menopausal breast cancers
    • O'Neill PA, Davies MP, Shaaban AM, et al. Wild-type oestrogen receptor beta (ERbeta1) mRNA and protein expression in Tamoxifen-treated post-menopausal breast cancers. Br J Cancer 2004; 91: 1694-702.
    • (2004) Br J Cancer , vol.91 , pp. 1694-1702
    • O'Neill, P.A.1    Davies, M.P.2    Shaaban, A.M.3
  • 108
    • 11144354862 scopus 로고    scopus 로고
    • The expression of ER beta cx in human breast cancer and the relationship to endocrine therapy and survival
    • Palmieri C, Lam EW, Mansi J, et al. The expression of ER beta cx in human breast cancer and the relationship to endocrine therapy and survival. Clin Cancer Res 2004; 10: 2421-8.
    • (2004) Clin Cancer Res , vol.10 , pp. 2421-2428
    • Palmieri, C.1    Lam, E.W.2    Mansi, J.3
  • 110
    • 33646838418 scopus 로고    scopus 로고
    • The changes of estrogen receptor-beta variants expression in breast carcinogenesis: Decrease of estrogen receptor-beta2 expression is the key event in breast cancer development
    • Park BW, Kim KS, Heo MK, et al. The changes of estrogen receptor-beta variants expression in breast carcinogenesis: Decrease of estrogen receptor-beta2 expression is the key event in breast cancer development. J Surg Oncol 2006; 93: 504-10.
    • (2006) J Surg Oncol , vol.93 , pp. 504-510
    • Park, B.W.1    Kim, K.S.2    Heo, M.K.3
  • 111
    • 33748305646 scopus 로고    scopus 로고
    • Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours
    • Skliris GP, Leygue E, Curtis-Snell L, Watson PH, Murphy LC. Expression of oestrogen receptor-beta in oestrogen receptor-alpha negative human breast tumours. Br J Cancer 2006; 95: 616-26.
    • (2006) Br J Cancer , vol.95 , pp. 616-626
    • Skliris, G.P.1    Leygue, E.2    Curtis-Snell, L.3    Watson, P.H.4    Murphy, L.C.5
  • 112
    • 34247491944 scopus 로고    scopus 로고
    • Estrogen receptor beta expression is associated with tamoxifen response in ERalpha-negative breast carcinoma
    • Gruvberger-Saal SK, Bendahl PO, Saal LH, et al. Estrogen receptor beta expression is associated with tamoxifen response in ERalpha-negative breast carcinoma. Clin Cancer Res 2007; 13: 1987-94.
    • (2007) Clin Cancer Res , vol.13 , pp. 1987-1994
    • Gruvberger-Saal, S.K.1    Bendahl, P.O.2    Saal, L.H.3
  • 113
    • 34548186909 scopus 로고    scopus 로고
    • Association of oestrogen receptor beta 2 (ER beta 2/ER beta cx) with outcome of adjuvant endocrine treatment for primary breast cancer--a retrospective study
    • Vinayagam R, Sibson DR, Holcombe C, Aachi V, Davies MP. Association of oestrogen receptor beta 2 (ER beta 2/ER beta cx) with outcome of adjuvant endocrine treatment for primary breast cancer--a retrospective study. BMC Cancer 2007; 7: 131. http://www.biomedcentral.com/1471-2407/7/131.
    • (2007) BMC Cancer , vol.7 , pp. 131
    • Vinayagam, R.1    Sibson, D.R.2    Holcombe, C.3    Aachi, V.4    Davies, M.P.5
  • 114
    • 49249129393 scopus 로고    scopus 로고
    • Clinical importance of estrogen receptor-beta evaluation in breast cancer patients treated with adjuvant tamoxifen therapy
    • Honma N, Horii R, Iwase T, et al. Clinical importance of estrogen receptor-beta evaluation in breast cancer patients treated with adjuvant tamoxifen therapy. J Clin Oncol 2008; 26: 3727-34.
    • (2008) J Clin Oncol , vol.26 , pp. 3727-3734
    • Honma, N.1    Horii, R.2    Iwase, T.3
  • 115
    • 59449088889 scopus 로고    scopus 로고
    • A divergent role for estrogen receptor-beta in node-positive and node-negative breast cancer classified according to molecular subtypes: An observational prospective study
    • Novelli F, Milella M, Melucci E, et al. A divergent role for estrogen receptor-beta in node-positive and node-negative breast cancer classified according to molecular subtypes: an observational prospective study. Breast Cancer Res 2008; 10: R74.
    • (2008) Breast Cancer Res , vol.10
    • Novelli, F.1    Milella, M.2    Melucci, E.3
  • 116
    • 52649152266 scopus 로고    scopus 로고
    • Nuclear and cytoplasmic expression of ERbeta1, ERbeta2, and ERbeta5 identifies distinct prognostic outcome for breast cancer patients
    • Shaaban AM, Green AR, Karthik S, et al. Nuclear and cytoplasmic expression of ERbeta1, ERbeta2, and ERbeta5 identifies distinct prognostic outcome for breast cancer patients. Clin Cancer Res 2008; 14: 5228-35.
    • (2008) Clin Cancer Res , vol.14 , pp. 5228-5235
    • Shaaban, A.M.1    Green, A.R.2    Karthik, S.3
  • 117
    • 77956512843 scopus 로고    scopus 로고
    • Phosphorylation of estrogen receptor beta at serine 105 is associated with good prognosis in breast cancer
    • Hamilton-Burke W, Coleman L, Cummings M, et al. Phosphorylation of estrogen receptor beta at serine 105 is associated with good prognosis in breast cancer. Am J Pathol 2010; 177: 1079-86.
    • (2010) Am J Pathol , vol.177 , pp. 1079-1086
    • Hamilton-Burke, W.1    Coleman, L.2    Cummings, M.3
  • 118
    • 78149302577 scopus 로고    scopus 로고
    • Expression of estrogen receptor beta and phosphorylation of estrogen receptor alpha serine 167 correlate with progression-free survival in patients with metastatic breast cancer treated with aromatase inhibitors
    • Motomura K, Ishitobi M, Komoike Y, et al. Expression of estrogen receptor beta and phosphorylation of estrogen receptor alpha serine 167 correlate with progression-free survival in patients with metastatic breast cancer treated with aromatase inhibitors. Oncology 2010; 79: 55-61.
    • (2010) Oncology , vol.79 , pp. 55-61
    • Motomura, K.1    Ishitobi, M.2    Komoike, Y.3
  • 119
    • 37149009490 scopus 로고    scopus 로고
    • Expression of estrogen receptor beta wild-type and its variant ERbetacx/beta2 is correlated with better prognosis in breast cancer
    • Sugiura H, Toyama T, Hara Y, et al. Expression of estrogen receptor beta wild-type and its variant ERbetacx/beta2 is correlated with better prognosis in breast cancer. Jpn J Clin Oncol 2007; 37: 820-8.
    • (2007) Jpn J Clin Oncol , vol.37 , pp. 820-828
    • Sugiura, H.1    Toyama, T.2    Hara, Y.3
  • 120
    • 0842291456 scopus 로고    scopus 로고
    • Differential recruitment of coregulator proteins steroid receptor coactivator-1 and silencing mediator for retinoid and thyroid receptors to the estrogen receptor-estrogen response element by betaestradiol and 4-hydroxytamoxifen in human breast cancer
    • Fleming FJ, Hill AD, McDermott EW, O'Higgins NJ, Young LS. Differential recruitment of coregulator proteins steroid receptor coactivator-1 and silencing mediator for retinoid and thyroid receptors to the estrogen receptor-estrogen response element by betaestradiol and 4-hydroxytamoxifen in human breast cancer. Clin Endocrinol Metab 2004; 89: 375-83.
    • (2004) Clin Endocrinol Metab , vol.89 , pp. 375-383
    • Fleming, F.J.1    Hill, A.D.2    McDermott, E.W.3    O'Higgins, N.J.4    Young, L.S.5
  • 121
    • 11244287448 scopus 로고    scopus 로고
    • Correlation of mRNA for oestrogen receptor beta splice variants ERbeta1, ERbeta2/ERbetacx and ERbeta5 with outcome in endocrine-treated breast cancer
    • Davies MP, O'Neill PA, Innes H, et al. Correlation of mRNA for oestrogen receptor beta splice variants ERbeta1, ERbeta2/ERbetacx and ERbeta5 with outcome in endocrine-treated breast cancer. J Mol Endocrinol 2004; 33: 773-82.
    • (2004) J Mol Endocrinol , vol.33 , pp. 773-782
    • Davies, M.P.1    O'Neill, P.A.2    Innes, H.3
  • 122
    • 79958746690 scopus 로고    scopus 로고
    • kConFab Investigators, Fox SB. Nuclear and cytoplasmic expressions of ERbeta1 and ERbeta2 are predictive of response to therapy and alters prognosis in familial breast cancers
    • Yan M, Rayoo M, Takano EA; kConFab Investigators, Fox SB. Nuclear and cytoplasmic expressions of ERbeta1 and ERbeta2 are predictive of response to therapy and alters prognosis in familial breast cancers. Breast Cancer Res Treat 2011; 126: 395-405.
    • (2011) Breast Cancer Res Treat , vol.126 , pp. 395-405
    • Yan, M.1    Rayoo, M.2    Takano, E.A.3
  • 123
    • 0003964363 scopus 로고    scopus 로고
    • American Cancer Society. Atlanta, American Cancer Society 2010
    • American Cancer Society. Cancer Facts & Figures 2010. Atlanta, American Cancer Society 2010.
    • (2010) Cancer Facts & Figures
  • 124
    • 61749095503 scopus 로고    scopus 로고
    • The dual, opposing roles of estrogen in the prostate
    • Review
    • Ellem SJ, Risbridger GP. The dual, opposing roles of estrogen in the prostate. Ann N Y Acad Sci 2009; 1155: 174-86. Review.
    • (2009) Ann N Y Acad Sci , vol.1155 , pp. 174-186
    • Ellem, S.J.1    Risbridger, G.P.2
  • 125
    • 34547235650 scopus 로고    scopus 로고
    • Treating prostate cancer: A rationale for targeting local oestrogens
    • Ellem SJ, Risbridger GP. Treating prostate cancer: a rationale for targeting local oestrogens. Nat Rev Cancer 2007; 7: 621-7.
    • (2007) Nat Rev Cancer , vol.7 , pp. 621-627
    • Ellem, S.J.1    Risbridger, G.P.2
  • 126
    • 0028220685 scopus 로고
    • Estradiol inhibits growth of hormone-nonresponsive PC3 human prostate cancer cells
    • Carruba G, Pfeffer U, Fecarotta E, et al. Estradiol inhibits growth of hormone-nonresponsive PC3 human prostate cancer cells. Cancer Res 1994; 54: 1190-3.
    • (1994) Cancer Res , vol.54 , pp. 1190-1193
    • Carruba, G.1    Pfeffer, U.2    Fecarotta, E.3
  • 127
    • 0028948092 scopus 로고
    • Growth of LNCaP human prostate cancer cells is stimulated by estradiol via its own receptor
    • Castagnetta L, Miceli MD, Sorci C, et al. Growth of LNCaP human prostate cancer cells is stimulated by estradiol via its own receptor. Endocrinology 1995; 136: 2309-19.
    • (1995) Endocrinology , vol.136 , pp. 2309-2319
    • Castagnetta, L.1    Miceli, M.D.2    Sorci, C.3
  • 128
    • 13844262629 scopus 로고    scopus 로고
    • Comparative effects of DHEA vs. testosterone, dihydrotestosterone, and estradiol on proliferation and gene expression in human LNCaP prostate cancer cells
    • Arnold JT, Le H., McFann KK, and Blackman MR. Comparative effects of DHEA vs. testosterone, dihydrotestosterone, and estradiol on proliferation and gene expression in human LNCaP prostate cancer cells. Am J Physiol Endocrinol Metab 2005; 288: E573-84.
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. 573-584
    • Arnold, J.T.1    Le, H.2    McFann, K.K.3    Blackman, M.R.4
  • 129
    • 2442626721 scopus 로고    scopus 로고
    • Expression of estrogen receptor beta in prostate carcinoma cells inhibits invasion and proliferation and triggers apoptosis
    • Cheng J, Lee EJ, Madison LD, Lazennec G. Expression of estrogen receptor beta in prostate carcinoma cells inhibits invasion and proliferation and triggers apoptosis. FEBS Lett 2004; 566: 169-72.
    • (2004) FEBS Lett , vol.566 , pp. 169-172
    • Cheng, J.1    Lee, E.J.2    Madison, L.D.3    Lazennec, G.4
  • 130
    • 34249659228 scopus 로고    scopus 로고
    • Estrogen receptor beta (ERbeta) and inhibition of prostate cancer cell proliferation: Studies on the possible mechanism of action in DU145 cells
    • Pravettoni A, Mornati O, Martini PG, et al. Estrogen receptor beta (ERbeta) and inhibition of prostate cancer cell proliferation: studies on the possible mechanism of action in DU145 cells. Mol Cell Endocrinol. 2007; 263: 46-54.
    • (2007) Mol Cell Endocrinol , vol.263 , pp. 46-54
    • Pravettoni, A.1    Mornati, O.2    Martini, P.G.3
  • 131
    • 77950476293 scopus 로고    scopus 로고
    • ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: Implications for Gleason grading
    • Mak P, Leav I, Pursell B, et al. ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading. Cancer Cell 2010; 17: 319-32.
    • (2010) Cancer Cell , vol.17 , pp. 319-332
    • Mak, P.1    Leav, I.2    Pursell, B.3
  • 132
    • 79151482563 scopus 로고    scopus 로고
    • 17 Estradiol regulates oxidative stress in prostate cancer cell lines according to ERalpha/ERbeta ratio
    • Miró AM, Sastre-Serra J, Pons DG, Valle A, Roca P, Oliver J. 17 Estradiol regulates oxidative stress in prostate cancer cell lines according to ERalpha/ERbeta ratio. J Steroid Biochem Mol Biol 2011; 123: 133-9.
    • (2011) J Steroid Biochem Mol Biol , vol.123 , pp. 133-139
    • Miró, A.M.1    Sastre-Serra, J.2    Pons, D.G.3    Valle, A.4    Roca, P.5    Oliver, J.6
  • 134
    • 43249092379 scopus 로고    scopus 로고
    • Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signaling
    • Ricke WA, McPherson SJ, Bianco JJ, Cunha GR, Wang Y, Risbridger GP. Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signaling. Faseb J 2008; 22: 1512-20.
    • (2008) Faseb J , vol.22 , pp. 1512-1520
    • Ricke, W.A.1    McPherson, S.J.2    Bianco, J.J.3    Cunha, G.R.4    Wang, Y.5    Risbridger, G.P.6
  • 135
    • 0035015891 scopus 로고    scopus 로고
    • Elevated androgens and prolactin in aromatase-deficient mice cause enlargement, but not malignancy, of the prostate gland
    • McPherson SJ, Wang H, Jones ME, et al. Elevated androgens and prolactin in aromatase-deficient mice cause enlargement, but not malignancy, of the prostate gland. Endocrinology 2001; 142: 2458-67.
    • (2001) Endocrinology , vol.142 , pp. 2458-2467
    • McPherson, S.J.1    Wang, H.2    Jones, M.E.3
  • 137
    • 77649253043 scopus 로고    scopus 로고
    • Estrogen receptor-beta activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFalpha mediated
    • McPherson SJ, Hussain S, Balanathan P, et al. Estrogen receptor-beta activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFalpha mediated. Proc Natl Acad Sci USA 2010; 107: 3123-8.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 3123-3128
    • McPherson, S.J.1    Hussain, S.2    Balanathan, P.3
  • 138
    • 0034486848 scopus 로고    scopus 로고
    • Immunocytochemical localization of estrogen receptors alpha and beta in the human reproductive organs
    • Pelletier G, El-Alfy M. Immunocytochemical localization of estrogen receptors alpha and beta in the human reproductive organs. J Clin Endocrinol Metab 2000; 85: 4835-40.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4835-4840
    • Pelletier, G.1    El-Alfy, M.2
  • 139
    • 0035408472 scopus 로고    scopus 로고
    • Comparative studies of the estrogen receptors beta and alpha and the androgen receptor in normal human prostate glands, dysplasia, and in primary and metastatic carcinoma
    • Leav I, Lau KM, Adams JY, et al. Comparative studies of the estrogen receptors beta and alpha and the androgen receptor in normal human prostate glands, dysplasia, and in primary and metastatic carcinoma. Am J Pathol 2001; 159: 79-92.
    • (2001) Am J Pathol , vol.159 , pp. 79-92
    • Leav, I.1    Lau, K.M.2    Adams, J.Y.3
  • 140
    • 0035082124 scopus 로고    scopus 로고
    • Estrogen receptors alpha and beta in the normal, hyperplastic and carcinomatous human prostate
    • Royuela M, de Miguel MP, Bethencourt FR, et al. Estrogen receptors alpha and beta in the normal, hyperplastic and carcinomatous human prostate. J Endocrinol 2001; 168: 447-54.
    • (2001) J Endocrinol , vol.168 , pp. 447-454
    • Royuela, M.1    de Miguel, M.P.2    Bethencourt, F.R.3
  • 141
    • 0037340497 scopus 로고    scopus 로고
    • Zone-dependent expression of estrogen receptors alpha and beta in human benign prostatic hyperplasia
    • Tsurusaki T, Aoki D, Kanetake H, et al. Zone-dependent expression of estrogen receptors alpha and beta in human benign prostatic hyperplasia. J Clin Endocrinol Metab 2003; 88: 1333-40.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1333-1340
    • Tsurusaki, T.1    Aoki, D.2    Kanetake, H.3
  • 142
    • 0035824392 scopus 로고    scopus 로고
    • Differential expression of estrogen receptor beta (ERbeta) and its C-terminal truncated splice variant ERbetacx as prognostic predictors in human prostatic cancer
    • Fujimura T, Takahashi S, Urano T, et al. Differential expression of estrogen receptor beta (ERbeta) and its C-terminal truncated splice variant ERbetacx as prognostic predictors in human prostatic cancer. Biochem Biophys Res Commun 2001; 289: 692-9.
    • (2001) Biochem Biophys Res Commun , vol.289 , pp. 692-699
    • Fujimura, T.1    Takahashi, S.2    Urano, T.3
  • 143
    • 0035878926 scopus 로고    scopus 로고
    • Frequent loss of estrogen receptor-beta expression in prostate cancer
    • Horvath LG, Henshall SM, Lee CS, et al. Frequent loss of estrogen receptor-beta expression in prostate cancer. Cancer Res 2001; 61: 5331-5.
    • (2001) Cancer Res , vol.61 , pp. 5331-5335
    • Horvath, L.G.1    Henshall, S.M.2    Lee, C.S.3
  • 144
    • 0035266404 scopus 로고    scopus 로고
    • Evaluation of androgen, estrogen (ER alpha and ER beta), and progesterone receptor expression in human prostate cancer by real-time quantitative reverse transcription-polymerase chain reaction assays
    • Latil A, Bièche I, Vidaud D, Lidereau R, Berthon P, Cussenot O, Vidaud M. Evaluation of androgen, estrogen (ER alpha and ER beta), and progesterone receptor expression in human prostate cancer by real-time quantitative reverse transcription-polymerase chain reaction assays. Cancer Res 2001; 61: 1919-26.
    • (2001) Cancer Res , vol.61 , pp. 1919-1926
    • Latil, A.1    Bièche, I.2    Vidaud, D.3    Lidereau, R.4    Berthon, P.5    Cussenot, O.6    Vidaud, M.7
  • 145
    • 0037304336 scopus 로고    scopus 로고
    • Differential expression of the estrogen receptor beta (ER beta) in human prostate tissue, premalignant changes, and in primary, metastatic, and recurrent prostatic adenocarcinoma
    • Fixemer T, Remberger K, Bonkhoff H. Differential expression of the estrogen receptor beta (ER beta) in human prostate tissue, premalignant changes, and in primary, metastatic, and recurrent prostatic adenocarcinoma. Prostate 2003; 54: 79-87.
    • (2003) Prostate , vol.54 , pp. 79-87
    • Fixemer, T.1    Remberger, K.2    Bonkhoff, H.3
  • 146
    • 66449130218 scopus 로고    scopus 로고
    • Endothelial NOS, estrogen receptor beta, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancer
    • Nanni S, Benvenuti V, Grasselli A, et al. Endothelial NOS, estrogen receptor beta, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancer. J Clin Invest. 2009; 119: 1093-108.
    • (2009) J Clin Invest , vol.119 , pp. 1093-1108
    • Nanni, S.1    Benvenuti, V.2    Grasselli, A.3
  • 147
    • 77957843261 scopus 로고    scopus 로고
    • Expression of estrogen related proteins in hormone refractory prostate cancer: Association with tumor progression
    • Celhay O, Yacoub M, Irani J, Dore B, Cussenot O, Fromont G. Expression of estrogen related proteins in hormone refractory prostate cancer: association with tumor progression. J Urol 2010; 184: 2172-8.
    • (2010) J Urol , vol.184 , pp. 2172-2178
    • Celhay, O.1    Yacoub, M.2    Irani, J.3    Dore, B.4    Cussenot, O.5    Fromont, G.6
  • 148
    • 77956363192 scopus 로고    scopus 로고
    • Estrogen receptor beta2 and beta5 are associated with poor prognosis in prostate cancer, and promote cancer cell migration and invasion
    • Leung YK, Lam HM, Wu S, et al. Estrogen receptor beta2 and beta5 are associated with poor prognosis in prostate cancer, and promote cancer cell migration and invasion. Endocr Relat Cancer 2010; 17: 675-89.
    • (2010) Endocr Relat Cancer , vol.17 , pp. 675-689
    • Leung, Y.K.1    Lam, H.M.2    Wu, S.3
  • 149
    • 38649140488 scopus 로고    scopus 로고
    • The role of estrogens and estrogen receptors in normal prostate growth and disease
    • Review
    • Prins GS, Korach KS. The role of estrogens and estrogen receptors in normal prostate growth and disease. Steroids. 2008; 73: 233-44. Review
    • (2008) Steroids , vol.73 , pp. 233-244
    • Prins, G.S.1    Korach, K.S.2
  • 150
    • 0035912874 scopus 로고    scopus 로고
    • Estrogen receptor beta expression in human prostate tissue
    • Pasquali D, Staibano S, Prezioso D, et al. Estrogen receptor beta expression in human prostate tissue. Mol Cell Endocrinol. 2001; 178: 47-50.
    • (2001) Mol Cell Endocrinol , vol.178 , pp. 47-50
    • Pasquali, D.1    Staibano, S.2    Prezioso, D.3
  • 152
    • 35648959800 scopus 로고    scopus 로고
    • Estrogen and prostate cancer: An eclipsed truth in an androgen-dominated scenario
    • Review
    • Carruba G. Estrogen and prostate cancer: an eclipsed truth in an androgen-dominated scenario. J Cell Biochem 2007; 102: 899-911. Review.
    • (2007) J Cell Biochem , vol.102 , pp. 899-911
    • Carruba, G.1
  • 153
    • 65549136111 scopus 로고    scopus 로고
    • Quantitative RT-PCR analysis of estrogen receptor gene expression in laser microdissected prostate cancer tissue
    • Walton TJ, Li G, McCulloch TA, et al. Quantitative RT-PCR analysis of estrogen receptor gene expression in laser microdissected prostate cancer tissue. Prostate 2009; 69: 810-9.
    • (2009) Prostate , vol.69 , pp. 810-819
    • Walton, T.J.1    Li, G.2    McCulloch, T.A.3
  • 154
    • 7444249518 scopus 로고    scopus 로고
    • Metastases of prostate cancer express estrogen receptor-beta
    • Lai JS, Brown LG, True LD, et al. Metastases of prostate cancer express estrogen receptor-beta. Urology 2004; 64: 814-20.
    • (2004) Urology , vol.64 , pp. 814-820
    • Lai, J.S.1    Brown, L.G.2    True, L.D.3
  • 155
    • 0028943552 scopus 로고
    • Health CW Jr Estrogen replacement therapy and risk of fatal colon cancer in a prospective cohort of postmenopausal women
    • Calle EE, Miracle-Mahill HL, Thun MJ, Health CW Jr Estrogen replacement therapy and risk of fatal colon cancer in a prospective cohort of postmenopausal women. J Natl Cancer Inst 1995; 87: 517-23.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 517-523
    • Calle, E.E.1    Miracle-Mahill, H.L.2    Thun, M.J.3
  • 156
    • 0029068856 scopus 로고
    • Postmenopausal hormone use and risk of large-bowel cancer
    • Newcomb PA & Storer BE. Postmenopausal hormone use and risk of large-bowel cancer. JNCI 1995; 87: 1067-71.
    • (1995) JNCI , vol.87 , pp. 1067-1071
    • Newcomb, P.A.1    Storer, B.E.2
  • 157
    • 0030942905 scopus 로고    scopus 로고
    • Hormone replacement therapy, reproductive history, and colon cancer: A multi-center, case-control study in the United States
    • Kampman E, Potter JD, Slattery ML, Caan BJ, Edwards S. Hormone replacement therapy, reproductive history, and colon cancer: a multi-center, case-control study in the United States. Cancer Causes and Control 1997; 8: 146-58.
    • (1997) Cancer Causes and Control , vol.8 , pp. 146-158
    • Kampman, E.1    Potter, J.D.2    Slattery, M.L.3    Caan, B.J.4    Edwards, S.5
  • 159
    • 0037125379 scopus 로고    scopus 로고
    • Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results From the Women's Health Initiative randomized controlled trial
    • Rossouw JE, Anderson GL, Prentice RL, et al. Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA 2002; 288: 321-33.
    • (2002) JAMA , vol.288 , pp. 321-333
    • Rossouw, J.E.1    Anderson, G.L.2    Prentice, R.L.3
  • 161
    • 0036739344 scopus 로고    scopus 로고
    • Oestrogeninduced apoptosis in colonocytes expressing oestrogen receptor beta
    • Qiu Y, Waters CE, Lewis AE, Langman MJ, Eggo MC. Oestrogeninduced apoptosis in colonocytes expressing oestrogen receptor beta. J Endocrinol 2002; 174: 369-77.
    • (2002) J Endocrinol , vol.174 , pp. 369-377
    • Qiu, Y.1    Waters, C.E.2    Lewis, A.E.3    Langman, M.J.4    Eggo, M.C.5
  • 162
    • 33747100321 scopus 로고    scopus 로고
    • Apoptotic effects of overexpressed estrogen receptor-beta on LoVo colon cancer cell is mediated by p53 signalings in a ligand-dependent manner
    • Hsu HH, Cheng SF, Wu CC, et al. Apoptotic effects of overexpressed estrogen receptor-beta on LoVo colon cancer cell is mediated by p53 signalings in a ligand-dependent manner. Chin J Physiol 2006; 49: 110-16.
    • (2006) Chin J Physiol , vol.49 , pp. 110-116
    • Hsu, H.H.1    Cheng, S.F.2    Wu, C.C.3
  • 163
    • 33745173166 scopus 로고    scopus 로고
    • Nitric oxide impairs the 17beta-estradiol-induced apoptosis in human colon adenocarcinoma cells
    • Marino M, Galluzzo P, Leone S, Acconcia F, Ascenzi P. Nitric oxide impairs the 17beta-estradiol-induced apoptosis in human colon adenocarcinoma cells. Endocr Relat Cancer 2006; 13: 559-69.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 559-569
    • Marino, M.1    Galluzzo, P.2    Leone, S.3    Acconcia, F.4    Ascenzi, P.5
  • 164
    • 34249712435 scopus 로고    scopus 로고
    • 17beta-Estradiol induces ERbeta up-regulation via p38/MAPK activation in colon cancer cells
    • Caiazza F, Galluzzo P, Lorenzetti S, Marino M. 17beta-Estradiol induces ERbeta up-regulation via p38/MAPK activation in colon cancer cells. Biochem Biophys Res Commun 2007; 359: 102-07.
    • (2007) Biochem Biophys Res Commun , vol.359 , pp. 102-107
    • Caiazza, F.1    Galluzzo, P.2    Lorenzetti, S.3    Marino, M.4
  • 165
    • 21244472672 scopus 로고    scopus 로고
    • Erbeta is a potent inhibitor of cell proliferation in the HCT8 human colon cancer cell line through regulation of cell cycle components
    • Martineti V, Picariello L, Tognarini I, et al. Erbeta is a potent inhibitor of cell proliferation in the HCT8 human colon cancer cell line through regulation of cell cycle components. Endocr Relat Cancer 2005; 12: 455-69.
    • (2005) Endocr Relat Cancer , vol.12 , pp. 455-469
    • Martineti, V.1    Picariello, L.2    Tognarini, I.3
  • 166
    • 79957667295 scopus 로고    scopus 로고
    • Estrogen Receptor {beta} Induces Antiinflammatory and Antitumorigenic Networks in Colon Cancer Cells
    • Edvardsson K, Ström A, Jonsson P, Gustafsson JA, Williams C. Estrogen Receptor {beta} Induces Antiinflammatory and Antitumorigenic Networks in Colon Cancer Cells. Mol Endocrinol 2011; 25: 969-79.
    • (2011) Mol Endocrinol , vol.25 , pp. 969-979
    • Edvardsson, K.1    Ström, A.2    Jonsson, P.3    Gustafsson, J.A.4    Williams, C.5
  • 167
    • 33644598617 scopus 로고    scopus 로고
    • Role of estrogen receptor beta in colonic epithelium
    • Wada-Hiraike O, Imamov O, Hiraike H, et al. Role of estrogen receptor beta in colonic epithelium. Proc Natl Acad Sci USA 2006; 103: 2959-64.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2959-2964
    • Wada-Hiraike, O.1    Imamov, O.2    Hiraike, H.3
  • 168
    • 71549171121 scopus 로고    scopus 로고
    • Estradiol alters cell growth in nonmalignant colonocytes and reduces the formation of preneoplastic lesions in the colon
    • Weige CC, Allred KF, Allred CD. Estradiol alters cell growth in nonmalignant colonocytes and reduces the formation of preneoplastic lesions in the colon. Cancer Res 2009; 69: 9118-24.
    • (2009) Cancer Res , vol.69 , pp. 9118-9124
    • Weige, C.C.1    Allred, K.F.2    Allred, C.D.3
  • 169
    • 0035866476 scopus 로고    scopus 로고
    • Reciprocal expression of ERalpha and ERbeta is associated with estrogenmediated modulation of intestinal tumorigenesis
    • Weyant MJ, Carothers AM, Mahmoud NN, et al. Reciprocal expression of ERalpha and ERbeta is associated with estrogenmediated modulation of intestinal tumorigenesis. Cancer Res 2001; 61: 2547-51.
    • (2001) Cancer Res , vol.61 , pp. 2547-2551
    • Weyant, M.J.1    Carothers, A.M.2    Mahmoud, N.N.3
  • 170
    • 44949170611 scopus 로고    scopus 로고
    • Estrogen receptor beta deficiency enhances small intestinal tumorigenesis in ApcMin/+ mice
    • Giroux V, Lemay F, Bernatchez G, Robitaille Y, Carrier JC. Estrogen receptor beta deficiency enhances small intestinal tumorigenesis in ApcMin/+ mice. Int J Cancer 2008; 123: 303-11.
    • (2008) Int J Cancer , vol.123 , pp. 303-311
    • Giroux, V.1    Lemay, F.2    Bernatchez, G.3    Robitaille, Y.4    Carrier, J.C.5
  • 171
    • 60249084249 scopus 로고    scopus 로고
    • The inhibitory effect of diarylpropionitrile, a selective agonist of estrogen receptor beta, on the growth of MC38 colon cancer line
    • Motylewska E, Stasikowska O, Mee-Mucha G. The inhibitory effect of diarylpropionitrile, a selective agonist of estrogen receptor beta, on the growth of MC38 colon cancer line. Cancer Lett 2009; 276: 68-73.
    • (2009) Cancer Lett , vol.276 , pp. 68-73
    • Motylewska, E.1    Stasikowska, O.2    Mee-Mucha, G.3
  • 172
    • 79953773923 scopus 로고    scopus 로고
    • Chemopreventive effect of ER -Selective agonist on intestinal tumorigenesis in Apc(Min/+) Mice
    • Giroux V, Bernatchez G, Carrier JC. Chemopreventive effect of ER -Selective agonist on intestinal tumorigenesis in Apc(Min/+) Mice. Mol Carcinog 2011; 50: 359-69.
    • (2011) Mol Carcinog , vol.50 , pp. 359-369
    • Giroux, V.1    Bernatchez, G.2    Carrier, J.C.3
  • 173
    • 77951095127 scopus 로고    scopus 로고
    • Oestrogen receptor-beta signalling protects against transplanted skin tumour growth in the mouse
    • Cho JL, Allanson M, Reeve VE. Oestrogen receptor-beta signalling protects against transplanted skin tumour growth in the mouse. Photochem Photobiol Sci 2010; 9: 608-14.
    • (2010) Photochem Photobiol Sci , vol.9 , pp. 608-614
    • Cho, J.L.1    Allanson, M.2    Reeve, V.E.3
  • 174
    • 0031044845 scopus 로고    scopus 로고
    • Snochowski M & Hurst RE Molecular study of sex steroid receptor gene expression in human colon and in colorectal carcinomas
    • Waliszewski P, Blaszczyk M, Wolinska-Witort E, Drews M, Snochowski M & Hurst RE Molecular study of sex steroid receptor gene expression in human colon and in colorectal carcinomas. J Surg Oncol 1997; 64: 3-11.
    • (1997) J Surg Oncol , vol.64 , pp. 3-11
    • Waliszewski, P.1    Blaszczyk, M.2    Wolinska-Witort, E.3    Drews, M.4
  • 176
    • 0035863409 scopus 로고    scopus 로고
    • Expression of estrogen receptor (ER) subtypes and ERb isoforms in colon cancer
    • Campbell-Thompson M, Lynch IJ, Bhardwaj B. Expression of estrogen receptor (ER) subtypes and ERb isoforms in colon cancer. Cancer Res 2001; 61: 632-40.
    • (2001) Cancer Res , vol.61 , pp. 632-640
    • Campbell-Thompson, M.1    Lynch, I.J.2    Bhardwaj, B.3
  • 177
    • 0034811991 scopus 로고    scopus 로고
    • Estrogen receptor beta is expressed in human colorectal adenocarcinoma
    • Witte D, Chirala M, Younes A, Li Y, Younes M. Estrogen receptor beta is expressed in human colorectal adenocarcinoma Hum Pathol 2001; 32: 940-4.
    • (2001) Hum Pathol , vol.32 , pp. 940-944
    • Witte, D.1    Chirala, M.2    Younes, A.3    Li, Y.4    Younes, M.5
  • 178
    • 0038579655 scopus 로고    scopus 로고
    • Oestrogen receptor beta (ERb) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation
    • Konstantinopoulos PA, Kominea A, Vandoros G, et al. Oestrogen receptor beta (ERb) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation, Eur J Cancer 2003; 39: 1251-8.
    • (2003) Eur J Cancer , vol.39 , pp. 1251-1258
    • Konstantinopoulos, P.A.1    Kominea, A.2    Vandoros, G.3
  • 179
    • 23944475103 scopus 로고    scopus 로고
    • ERbeta isoform expression in colorectal carcinoma: An in vivo and in vitro study of clinicopathological and molecular correlates
    • Wong NA, Malcomson RD, Jodrell DI, Groome NP, Harrison DJ, Saunders PT. ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates. J Pathol 2005; 207: 53-60.
    • (2005) J Pathol , vol.207 , pp. 53-60
    • Wong, N.A.1    Malcomson, R.D.2    Jodrell, D.I.3    Groome, N.P.4    Harrison, D.J.5    Saunders, P.T.6
  • 180
    • 57649124231 scopus 로고    scopus 로고
    • Expression of estrogen beta receptors in colon cancer progression
    • Castiglione F, Taddei A, Degl'Innocenti DR, et al. Expression of estrogen beta receptors in colon cancer progression. Diagn Mol Pathol 2008; 17: 231-6.
    • (2008) Diagn Mol Pathol , vol.17 , pp. 231-236
    • Castiglione, F.1    Taddei, A.2    Degl'Innocenti, D.R.3
  • 181
    • 78449266131 scopus 로고    scopus 로고
    • Prognostic impact of ER and MMP7 expression on overall survival in colon cancer
    • Fang YJ, Lu ZH, Wang F, et al. Prognostic impact of ER and MMP7 expression on overall survival in colon cancer. Tumour Biol 2010; 31: 651-8.
    • (2010) Tumour Biol , vol.31 , pp. 651-658
    • Fang, Y.J.1    Lu, Z.H.2    Wang, F.3
  • 183
    • 1842845076 scopus 로고    scopus 로고
    • Lung cancer in US women: A contemporary epidemic
    • Patel JD, Bach PB, Kris MG. Lung cancer in US women: a contemporary epidemic. JAMA 2004; 291: 1763-8.
    • (2004) JAMA , vol.291 , pp. 1763-1768
    • Patel, J.D.1    Bach, P.B.2    Kris, M.G.3
  • 184
    • 0028451468 scopus 로고
    • Endocrine factors and adenocarcinoma of the lung in women
    • Taioli E, Wynder EL. Endocrine factors and adenocarcinoma of the lung in women. J Natl Cancer Inst 1994; 86: 869-70.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 869-870
    • Taioli, E.1    Wynder, E.L.2
  • 185
    • 33644838866 scopus 로고    scopus 로고
    • Hormone replacement therapy is associated with decreased survival in women with lung cancer
    • Ganti AK, Sahmoun AE, Panwalkar AW, Tendulkar KK, Potti A. Hormone replacement therapy is associated with decreased survival in women with lung cancer. J Clin Oncol 2006; 24: 59-63.
    • (2006) J Clin Oncol , vol.24 , pp. 59-63
    • Ganti, A.K.1    Sahmoun, A.E.2    Panwalkar, A.W.3    Tendulkar, K.K.4    Potti, A.5
  • 186
    • 70349783733 scopus 로고    scopus 로고
    • Oestrogen plus progestin and lung cancer in postmenopausal women (Women's Health Initiative trial): A post-hoc analysis of a randomized controlled trial
    • Chlebowski RT, Schwartz AG, Wakelee H, et al. Oestrogen plus progestin and lung cancer in postmenopausal women (Women's Health Initiative trial): a post-hoc analysis of a randomized controlled trial. Lancet 2009; 374: 1243-51.
    • (2009) Lancet , vol.374 , pp. 1243-1251
    • Chlebowski, R.T.1    Schwartz, A.G.2    Wakelee, H.3
  • 189
    • 37649003387 scopus 로고    scopus 로고
    • Reproductive factors, hormone use, estrogen receptor expression and risk of non small-cell lung cancer in women
    • Schwartz AG, Wenzlaff AS, Prysak GM, et al. Reproductive factors, hormone use, estrogen receptor expression and risk of non small-cell lung cancer in women. J Clin Oncol 2007; 25: 5785-92.
    • (2007) J Clin Oncol , vol.25 , pp. 5785-5792
    • Schwartz, A.G.1    Wenzlaff, A.S.2    Prysak, G.M.3
  • 190
    • 51649084814 scopus 로고    scopus 로고
    • Intratumoral estrogens and estrogen receptors in human non-small cell lung carcinoma
    • Niikawa H, Suzuki T, Miki Y, et al. Intratumoral estrogens and estrogen receptors in human non-small cell lung carcinoma. Clin Cancer Res 2008; 14: 4417-26.
    • (2008) Clin Cancer Res , vol.14 , pp. 4417-4426
    • Niikawa, H.1    Suzuki, T.2    Miki, Y.3
  • 191
    • 13944261544 scopus 로고    scopus 로고
    • Regulation of endogenous gene expression in human non-small cell lung cancer cells by estrogen receptor ligands
    • Hershberger PA, Vasquez AC, Kanterewicz B, Land S, Siegfried JM, Nichols M. Regulation of endogenous gene expression in human non-small cell lung cancer cells by estrogen receptor ligands. Cancer Res 2005; 65: 1598-605.
    • (2005) Cancer Res , vol.65 , pp. 1598-1605
    • Hershberger, P.A.1    Vasquez, A.C.2    Kanterewicz, B.3    Land, S.4    Siegfried, J.M.5    Nichols, M.6
  • 192
    • 67449094349 scopus 로고    scopus 로고
    • Estrogen receptor beta (ERbeta) subtype-specific ligands increase transcription, p44/p42 mitogen activated protein kinase (MAPK) activation and growth in human non-small cell lung cancer cells
    • Hershberger PA, Stabile LP, Kanterewicz B, et al. Estrogen receptor beta (ERbeta) subtype-specific ligands increase transcription, p44/p42 mitogen activated protein kinase (MAPK) activation and growth in human non-small cell lung cancer cells. J Steroid Biochem Mol Biol 2009; 116: 102-9.
    • (2009) J Steroid Biochem Mol Biol , vol.116 , pp. 102-109
    • Hershberger, P.A.1    Stabile, L.P.2    Kanterewicz, B.3
  • 193
    • 58849143026 scopus 로고    scopus 로고
    • Estrogen receptor beta functions through nongenomic mechanisms in lung cancer cells
    • Zhang G, Liu X, Farkas AM, et al. Estrogen receptor beta functions through nongenomic mechanisms in lung cancer cells. Mol Endocrinol 2009; 23: 146-56.
    • (2009) Mol Endocrinol , vol.23 , pp. 146-156
    • Zhang, G.1    Liu, X.2    Farkas, A.M.3
  • 195
    • 0036532167 scopus 로고    scopus 로고
    • Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor alpha and beta and show biological responses to estrogen
    • Stabile LP, Davis AL, Gubish CT, et al. Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor alpha and beta and show biological responses to estrogen. Cancer Res 2002; 62: 2141-50.
    • (2002) Cancer Res , vol.62 , pp. 2141-2150
    • Stabile, L.P.1    Davis, A.L.2    Gubish, C.T.3
  • 196
    • 0034811996 scopus 로고    scopus 로고
    • Expression, function, and clinical implications of the estrogen receptor beta in human lung cancers
    • Omoto Y, Kobayashi Y, Nishida K, et al. Expression, function, and clinical implications of the estrogen receptor beta in human lung cancers. Biochem Biophys Res Commun 2001; 285: 340-7.
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 340-347
    • Omoto, Y.1    Kobayashi, Y.2    Nishida, K.3
  • 197
    • 22344449903 scopus 로고    scopus 로고
    • Estrogen Receptor alfa and beta are Prognostic Factors in Non-Small Cell Lung Cancer
    • Kawai H, Ishii A, Washiya K, Konno T, et al. Estrogen Receptor alfa and beta are Prognostic Factors in Non-Small Cell Lung Cancer. Clin Cancer Res 2005; 11: 5084-9.
    • (2005) Clin Cancer Res , vol.11 , pp. 5084-5089
    • Kawai, H.1    Ishii, A.2    Washiya, K.3    Konno, T.4
  • 198
    • 27144527294 scopus 로고    scopus 로고
    • Nuclear estrogen receptor beta in lung cancer: Expression and survival differences by sex
    • Schwartz AG, Prysak GM, Murphy V, et al. Nuclear estrogen receptor beta in lung cancer: expression and survival differences by sex. Clin Cancer Res 2005; 11: 7280-7.
    • (2005) Clin Cancer Res , vol.11 , pp. 7280-7287
    • Schwartz, A.G.1    Prysak, G.M.2    Murphy, V.3
  • 199
    • 26444533390 scopus 로고    scopus 로고
    • The significance of estrogen receptor beta in 301 surgically treated non-small cell lung cancers
    • Wu CT, Chang YL, Shih JY, Lee YC. The significance of estrogen receptor beta in 301 surgically treated non-small cell lung cancers. J Thorac Cardiovasc Surg 2005; 130: 979-86.
    • (2005) J Thorac Cardiovasc Surg , vol.130 , pp. 979-986
    • Wu, C.T.1    Chang, Y.L.2    Shih, J.Y.3    Lee, Y.C.4
  • 200
    • 37549012508 scopus 로고    scopus 로고
    • Oestrogen receptor over expression in males with non-small cell lung cancer is associated with better survival
    • Skov BG, Fischer BM, Pappot H. Oestrogen receptor over expression in males with non-small cell lung cancer is associated with better survival. Lung Cancer 2008; 59: 88-94.
    • (2008) Lung Cancer , vol.59 , pp. 88-94
    • Skov, B.G.1    Fischer, B.M.2    Pappot, H.3
  • 201
    • 58549109862 scopus 로고    scopus 로고
    • Association between estrogen receptor-beta expression and epidermal growth factor receptor mutation in the postoperative prognosis of adenocarcinoma of the lung
    • Nose N, Sugio K, Oyama T, et al. Association between estrogen receptor-beta expression and epidermal growth factor receptor mutation in the postoperative prognosis of adenocarcinoma of the lung. J Clin Oncol. 2009; 27: 411-7.
    • (2009) J Clin Oncol , vol.27 , pp. 411-417
    • Nose, N.1    Sugio, K.2    Oyama, T.3
  • 202
    • 79851513555 scopus 로고    scopus 로고
    • Expression of estrogen receptor beta predicts a clinical response and longer progression-free survival after treatment with EGFR-TKI for adenocarcinoma of the lung
    • Nose N, Uramoto H, Iwata T, Hanagiri T, Yasumoto K. Expression of estrogen receptor beta predicts a clinical response and longer progression-free survival after treatment with EGFR-TKI for adenocarcinoma of the lung. Lung Cancer 2011; 71: 350-5.
    • (2011) Lung Cancer , vol.71 , pp. 350-355
    • Nose, N.1    Uramoto, H.2    Iwata, T.3    Hanagiri, T.4    Yasumoto, K.5
  • 203
    • 78751521520 scopus 로고    scopus 로고
    • Combined analysis of estrogen receptor {beta}-1 and progesterone receptor expression identifies lung cancer patients with poor outcome
    • Stabile LP, Dacic S, Land SR, et al. Combined analysis of estrogen receptor {beta}-1 and progesterone receptor expression identifies lung cancer patients with poor outcome. Clin Cancer Res 2011; 17: 154-64.
    • (2011) Clin Cancer Res , vol.17 , pp. 154-164
    • Stabile, L.P.1    Dacic, S.2    Land, S.R.3
  • 204
    • 69949088331 scopus 로고    scopus 로고
    • Immunohistochemical expression of estrogen and progesterone receptors identifies a subset of NSCLCs and correlates with EGFR mutation
    • Raso MG, Behrens C, Herynk MH, et al. Immunohistochemical expression of estrogen and progesterone receptors identifies a subset of NSCLCs and correlates with EGFR mutation. Clin Cancer Res 2009; 15: 5359-68.
    • (2009) Clin Cancer Res , vol.15 , pp. 5359-5368
    • Raso, M.G.1    Behrens, C.2    Herynk, M.H.3
  • 205
    • 79960252746 scopus 로고    scopus 로고
    • Suppression of estrogen actions in human lung cancer
    • Feb 25[Epub ahead of print]
    • Miki Y, Abe K, Suzuki S, Suzuki T, Sasano H. Suppression of estrogen actions in human lung cancer. Mol Cell Endocrinol. 2011 Feb 25[Epub ahead of print]
    • (2011) Mol Cell Endocrinol
    • Miki, Y.1    Abe, K.2    Suzuki, S.3    Suzuki, T.4    Sasano, H.5
  • 207
    • 12844284531 scopus 로고    scopus 로고
    • Endogenous hormones and ovarian cancer: Epidemiology and current hypotheses
    • Review
    • Lukanova A, Kaaks R. Endogenous hormones and ovarian cancer: epidemiology and current hypotheses. Cancer Epidemiol Biomarkers Prev 2005; 14: 98-107. Review.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 98-107
    • Lukanova, A.1    Kaaks, R.2
  • 209
    • 39249084221 scopus 로고    scopus 로고
    • Hormone replacement therapy and ovarian cancer risk: A meta-analysis
    • Zhou B, Sun Q, Cong R, et al. Hormone replacement therapy and ovarian cancer risk: a meta-analysis. Gynecol Oncol 2008; 108: 641-51.
    • (2008) Gynecol Oncol , vol.108 , pp. 641-651
    • Zhou, B.1    Sun, Q.2    Cong, R.3
  • 210
    • 0025281245 scopus 로고
    • Pregnancy, breast feeding, and oral contraceptives and the risk of epithelial ovarian cancer
    • Gwinn ML, Lee N, Rhodes PH, Layde PM, Rubin GL. Pregnancy, breast feeding, and oral contraceptives and the risk of epithelial ovarian cancer. J Clin Epidemiol 1989; 43: 559-68.
    • (1989) J Clin Epidemiol , vol.43 , pp. 559-568
    • Gwinn, M.L.1    Lee, N.2    Rhodes, P.H.3    Layde, P.M.4    Rubin, G.L.5
  • 211
    • 0029029163 scopus 로고
    • Endometrial and ovarian cancer and oral contraceptives-findings in a large cohort study
    • Vessey MP, Painter R. Endometrial and ovarian cancer and oral contraceptives-findings in a large cohort study. Br J Cancer 1995; 71: 1340-2.
    • (1995) Br J Cancer , vol.71 , pp. 1340-1342
    • Vessey, M.P.1    Painter, R.2
  • 212
    • 35848951366 scopus 로고    scopus 로고
    • Combined oral contraceptives: A comprehensive review
    • Kiley J, Hammond C. Combined oral contraceptives: a comprehensive review. Clin Obstet Gynecol 2007; 50: 868-77.
    • (2007) Clin Obstet Gynecol , vol.50 , pp. 868-877
    • Kiley, J.1    Hammond, C.2
  • 213
    • 0035992369 scopus 로고    scopus 로고
    • CA125 response is associated with estrogen receptor expression in a phase II trial of letrozole in ovarian cancer: Identification of an endocrine-sensitive subgroup
    • Bowman A, Gabra H, Langdon SP, et al. CA125 response is associated with estrogen receptor expression in a phase II trial of letrozole in ovarian cancer: identification of an endocrine-sensitive subgroup. Clin Cancer Res 2002; 8: 2233-9.
    • (2002) Clin Cancer Res , vol.8 , pp. 2233-2239
    • Bowman, A.1    Gabra, H.2    Langdon, S.P.3
  • 214
    • 2342545914 scopus 로고    scopus 로고
    • Hormonal therapy with letrozole for relapsed epithelial ovarian cancer. Long-term results of a phase II study
    • Papadimitriou CA, Markaki S, Siapkaras J, et al. Hormonal therapy with letrozole for relapsed epithelial ovarian cancer. Long-term results of a phase II study. Oncology 2004; 66: 112-7.
    • (2004) Oncology , vol.66 , pp. 112-117
    • Papadimitriou, C.A.1    Markaki, S.2    Siapkaras, J.3
  • 215
    • 0025935370 scopus 로고
    • Responsiveness of patients with advanced ovarian carcinoma to tamoxifen. A Gynecologic Oncology Group study of second-line therapy in 105 patients
    • Hatch KD, Beecham JB, Blessing JA, Creasman WT. Responsiveness of patients with advanced ovarian carcinoma to tamoxifen. A Gynecologic Oncology Group study of second-line therapy in 105 patients. Cancer 1991; 68: 269-71.
    • (1991) Cancer , vol.68 , pp. 269-271
    • Hatch, K.D.1    Beecham, J.B.2    Blessing, J.A.3    Creasman, W.T.4
  • 216
    • 0027504171 scopus 로고
    • Hormonal palliation of chemoresistant ovarian cancer: Three consecutive phase II trials of the Mid-Atlantic Oncology Program
    • Ahlgren JD, Ellison NM, Gottlieb RJ, et al. Hormonal palliation of chemoresistant ovarian cancer: three consecutive phase II trials of the Mid-Atlantic Oncology Program. J Clin Oncol 1993; 11: 195-768.
    • (1993) J Clin Oncol , vol.11 , pp. 195-768
    • Ahlgren, J.D.1    Ellison, N.M.2    Gottlieb, R.J.3
  • 217
    • 0033867902 scopus 로고    scopus 로고
    • Hormone therapy in epithelial ovarian cancer
    • Review
    • Makar AP. Hormone therapy in epithelial ovarian cancer. Endocr Relat Cancer 2000; 7: 85-93. Review.
    • (2000) Endocr Relat Cancer , vol.7 , pp. 85-93
    • Makar, A.P.1
  • 218
    • 0032430453 scopus 로고    scopus 로고
    • Estrogen and progesterone receptors in ovarian carcinoma
    • Scambia G, Ferrandina G, D'Ablaing G, et al. Estrogen and progesterone receptors in ovarian carcinoma. Endocr Relat Cancer 1998; 5: 293-301.
    • (1998) Endocr Relat Cancer , vol.5 , pp. 293-301
    • Scambia, G.1    Ferrandina, G.2    D'Ablaing, G.3
  • 219
    • 3242728753 scopus 로고    scopus 로고
    • Estrogens and epithelial ovarian cancer
    • Review
    • Cunat S, Hoffmann P, Pujol P. Estrogens and epithelial ovarian cancer. Gynecol Oncol. 2004; 94: 25-32. Review.
    • (2004) Gynecol Oncol , vol.94 , pp. 25-32
    • Cunat, S.1    Hoffmann, P.2    Pujol, P.3
  • 220
    • 29144512841 scopus 로고    scopus 로고
    • Estrogen receptor-alpha mediates gene expression changes and growth response in ovarian cancer cells exposed to estrogen
    • O'Donnell AJ, Macleod KG, Burns DJ, Smyth JF, Langdon SP. Estrogen receptor-alpha mediates gene expression changes and growth response in ovarian cancer cells exposed to estrogen. Endocr Relat Cancer 2005; 12: 851-66
    • (2005) Endocr Relat Cancer , vol.12 , pp. 851-866
    • O'Donnell, A.J.1    Macleod, K.G.2    Burns, D.J.3    Smyth, J.F.4    Langdon, S.P.5
  • 222
    • 34447096900 scopus 로고    scopus 로고
    • Estrogen receptor {beta}1 exerts antitumoral effects on SK-OV-3 ovarian cancer cells
    • Treeck O, Pfeiler G, Mitter D, Lattrich C, Piendl G, Ortmann O. Estrogen receptor {beta}1 exerts antitumoral effects on SK-OV-3 ovarian cancer cells. J Endocrinol 2007; 193: 421-33.
    • (2007) J Endocrinol , vol.193 , pp. 421-433
    • Treeck, O.1    Pfeiler, G.2    Mitter, D.3    Lattrich, C.4    Piendl, G.5    Ortmann, O.6
  • 223
    • 57349198790 scopus 로고    scopus 로고
    • Loss of estrogen receptor beta isoform expression and its correlation with aberrant DNA methylation of the 5'-untranslated region in human epithelial ovarian carcinoma
    • Suzuki F, Akahira J, Miura I, et al. Loss of estrogen receptor beta isoform expression and its correlation with aberrant DNA methylation of the 5'-untranslated region in human epithelial ovarian carcinoma. Cancer Sci 2008; 99: 2365-72.
    • (2008) Cancer Sci , vol.99 , pp. 2365-2372
    • Suzuki, F.1    Akahira, J.2    Miura, I.3
  • 226
    • 77950629251 scopus 로고    scopus 로고
    • Prognostic significance of estrogen receptor alpha and beta expression in human serous carcinomas of the ovary
    • Burges A, Brüning A, Dannenmann C, et al. Prognostic significance of estrogen receptor alpha and beta expression in human serous carcinomas of the ovary. Arch Gynecol Obstet 2010; 281: 511-7.
    • (2010) Arch Gynecol Obstet , vol.281 , pp. 511-517
    • Burges, A.1    Brüning, A.2    Dannenmann, C.3
  • 227
    • 0004629130 scopus 로고    scopus 로고
    • Estrogen receptor alpha (ER-alpha) and beta (ER-beta) mRNAs in normal ovary, ovarian serous cystadenocarcinoma and ovarian cancer cell lines: Downregulation of ER-beta in neoplastic tissues
    • Brandenberger AW, Tee MK, Jaffe RB. Estrogen receptor alpha (ER-alpha) and beta (ER-beta) mRNAs in normal ovary, ovarian serous cystadenocarcinoma and ovarian cancer cell lines: downregulation of ER-beta in neoplastic tissues. J Clin Endocrinol Metab 1998; 83: 1025-8.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1025-1028
    • Brandenberger, A.W.1    Tee, M.K.2    Jaffe, R.B.3
  • 228
    • 0032401855 scopus 로고    scopus 로고
    • Differential expression of estrogen receptor-alpha and -beta messenger RNAs as a potential marker of ovarian carcinogenesis
    • Pujol P, Rey JM, Nirde P, et al. Differential expression of estrogen receptor-alpha and -beta messenger RNAs as a potential marker of ovarian carcinogenesis. Cancer Res 1998; 58: 5367-73.
    • (1998) Cancer Res , vol.58 , pp. 5367-5373
    • Pujol, P.1    Rey, J.M.2    Nirde, P.3
  • 229
    • 29844458399 scopus 로고    scopus 로고
    • Estrogen receptor beta, a possible tumor suppressor involved in ovarian carcinogenesis
    • Lazennec G. Estrogen receptor beta, a possible tumor suppressor involved in ovarian carcinogenesis. Cancer Lett 2006; 231: 151-7.
    • (2006) Cancer Lett , vol.231 , pp. 151-157
    • Lazennec, G.1
  • 230
    • 77949503640 scopus 로고    scopus 로고
    • The importance of ER beta signalling in the ovary
    • Drummond AE, Fuller PJ. The importance of ER beta signalling in the ovary. J Endocrinol 2010; 205: 15-23.
    • (2010) J Endocrinol , vol.205 , pp. 15-23
    • Drummond, A.E.1    Fuller, P.J.2
  • 231
    • 79953233108 scopus 로고    scopus 로고
    • Loss of estrogen receptor Beta expression correlates with shorter overall survival and lack of clinical response to chemotherapy in ovarian cancer patients
    • Halon A, Nowak-Markwitz E, Maciejczyk A, et al. Loss of estrogen receptor Beta expression correlates with shorter overall survival and lack of clinical response to chemotherapy in ovarian cancer patients. Anticancer Res 2011; 31: 711-8.
    • (2011) Anticancer Res , vol.31 , pp. 711-718
    • Halon, A.1    Nowak-Markwitz, E.2    Maciejczyk, A.3
  • 232
    • 80051549162 scopus 로고    scopus 로고
    • Cytoplasmic expression of Estrogen Receptor beta (ER) predicts poor clinical outcome in advanced serous ovarian cancer
    • De Stefano I, Zannoni GF, Prisco MG, et al. Cytoplasmic expression of Estrogen Receptor beta (ER) predicts poor clinical outcome in advanced serous ovarian cancer. Gynecol Oncol 2011; 122: 573-9.
    • (2011) Gynecol Oncol , vol.122 , pp. 573-579
    • de Stefano, I.1    Zannoni, G.F.2    Prisco, M.G.3
  • 234
    • 67650469833 scopus 로고    scopus 로고
    • Resistance to chemotherapy and hormone therapy in endometrial cancer
    • Chaudhry P, Asselin E. Resistance to chemotherapy and hormone therapy in endometrial cancer. Endocr Relat Cancer 2009; 16: 363-80.
    • (2009) Endocr Relat Cancer , vol.16 , pp. 363-380
    • Chaudhry, P.1    Asselin, E.2
  • 235
    • 79953647162 scopus 로고    scopus 로고
    • Aromatase inhibition: A potential target for the management of recurrent or metastatic endometrial cancer by letrozole: More questions than answers?
    • Steed HL, Chu QS. Aromatase inhibition: a potential target for the management of recurrent or metastatic endometrial cancer by letrozole: more questions than answers? Expert Opin Investig Drugs 2011; 20: 681-90.
    • (2011) Expert Opin Investig Drugs , vol.20 , pp. 681-690
    • Steed, H.L.1    Chu, Q.S.2
  • 236
    • 0022891813 scopus 로고
    • Effects of estradiol on proliferation of endometrial adenocarcinoma cells (Ishikawa line)
    • Holinka CF, Hata H, Gravanis A, Kuramoto H, Gurpide E. Effects of estradiol on proliferation of endometrial adenocarcinoma cells (Ishikawa line). J Steroid Biochem 1986; 25: 781-6.
    • (1986) J Steroid Biochem , vol.25 , pp. 781-786
    • Holinka, C.F.1    Hata, H.2    Gravanis, A.3    Kuramoto, H.4    Gurpide, E.5
  • 237
    • 0036087615 scopus 로고    scopus 로고
    • Regulation of estrogen target genes and growth by selective estrogen-receptor modulators in endometrial cancer cells
    • Dardes RC, Schafer JM, Pearce ST, Osipo C, Chen B, Jordan VC. Regulation of estrogen target genes and growth by selective estrogen-receptor modulators in endometrial cancer cells. Gynecol Oncol 2002; 85: 498-506.
    • (2002) Gynecol Oncol , vol.85 , pp. 498-506
    • Dardes, R.C.1    Schafer, J.M.2    Pearce, S.T.3    Osipo, C.4    Chen, B.5    Jordan, V.C.6
  • 238
    • 53749107256 scopus 로고    scopus 로고
    • Synthesis, biological evaluation, structural-activity relationship, and docking study for a series of benzoxepin-derived estrogen receptor modulators
    • Barrett I, Meegan MJ, Hughes RB, et al. Synthesis, biological evaluation, structural-activity relationship, and docking study for a series of benzoxepin-derived estrogen receptor modulators. Bioorg Med Chem 2008; 16: 9554-73.
    • (2008) Bioorg Med Chem , vol.16 , pp. 9554-9573
    • Barrett, I.1    Meegan, M.J.2    Hughes, R.B.3
  • 239
    • 0034705032 scopus 로고    scopus 로고
    • Estrogen receptor (ER) beta, a modulator of ERalpha in the uterus
    • Weihua Z, Saji S, Makinen S, et al. Estrogen receptor (ER) beta, a modulator of ERalpha in the uterus. Proc Natl Acad Sci USA 2000; 97: 5936-41.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5936-5941
    • Weihua, Z.1    Saji, S.2    Makinen, S.3
  • 240
    • 67349106712 scopus 로고    scopus 로고
    • Immunohistochemical labelling of steroid receptors in normal and malignant human endometrium
    • Mylonas I, Makovitzky J, Friese K, Jeschke U. Immunohistochemical labelling of steroid receptors in normal and malignant human endometrium. Acta Histochem 2009; 111: 349-59.
    • (2009) Acta Histochem , vol.111 , pp. 349-359
    • Mylonas, I.1    Makovitzky, J.2    Friese, K.3    Jeschke, U.4
  • 241
    • 0036845348 scopus 로고    scopus 로고
    • Wild-type estrogen receptor (ERbeta1) and the splice variant (ERbetacx/beta2) are both expressed within the human endometrium throughout the normal menstrual cycle
    • Critchley HO, Henderson TA, Kelly RW, et al. Wild-type estrogen receptor (ERbeta1) and the splice variant (ERbetacx/beta2) are both expressed within the human endometrium throughout the normal menstrual cycle. J Clin Endocrinol Metab 2002; 87: 5265-73.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5265-5273
    • Critchley, H.O.1    Henderson, T.A.2    Kelly, R.W.3
  • 242
    • 0035909516 scopus 로고    scopus 로고
    • Well-differentiated endometrial adenocarcinomas and poorly differentiated mixed mullerian tumors have altered ER and PR isoform expression
    • Jazaeri AA, Nunes KJ, Dalton MS, Xu M, Shupnik MA, Rice LW. Well-differentiated endometrial adenocarcinomas and poorly differentiated mixed mullerian tumors have altered ER and PR isoform expression. Oncogene 2001; 20: 6965-9.
    • (2001) Oncogene , vol.20 , pp. 6965-6969
    • Jazaeri, A.A.1    Nunes, K.J.2    Dalton, M.S.3    Xu, M.4    Shupnik, M.A.5    Rice, L.W.6
  • 243
    • 0036285627 scopus 로고    scopus 로고
    • Clinical implications of the expression of estrogen receptor-alpha and -beta in primary and metastatic lesions of uterine endometrial cancers
    • Fujimoto J, Sakaguchi H, Aoki I, Toyoki H, Tamaya T. Clinical implications of the expression of estrogen receptor-alpha and -beta in primary and metastatic lesions of uterine endometrial cancers. Oncology 2002; 62: 269-77.
    • (2002) Oncology , vol.62 , pp. 269-277
    • Fujimoto, J.1    Sakaguchi, H.2    Aoki, I.3    Toyoki, H.4    Tamaya, T.5
  • 244
    • 2942563752 scopus 로고    scopus 로고
    • Evaluation of mRNA expression of estrogen receptor beta and its isoforms in human normal and neoplastic endometrium
    • Skrzypczak M, Bieche I, Szymczak S, et al. Evaluation of mRNA expression of estrogen receptor beta and its isoforms in human normal and neoplastic endometrium. Int J Cancer 2004; 110: 783-7.
    • (2004) Int J Cancer , vol.110 , pp. 783-787
    • Skrzypczak, M.1    Bieche, I.2    Szymczak, S.3
  • 245
    • 34447345990 scopus 로고    scopus 로고
    • Estrogen receptor beta1 and the beta2/betacx isoforms in nonneoplastic endometrium and in endometrioid carcinoma
    • Chakravarty D, Srinivasan R, Ghosh S, Gopalan S, Rajwanshi A, Majumdar S. Estrogen receptor beta1 and the beta2/betacx isoforms in nonneoplastic endometrium and in endometrioid carcinoma. Int J Gynecol Cancer 2007; 17: 905-13.
    • (2007) Int J Gynecol Cancer , vol.17 , pp. 905-913
    • Chakravarty, D.1    Srinivasan, R.2    Ghosh, S.3    Gopalan, S.4    Rajwanshi, A.5    Majumdar, S.6
  • 246
    • 27744584615 scopus 로고    scopus 로고
    • Breast cancer risk with postmenopausal hormonal treatment
    • Collins JA, Blake JM, Crosignani PG. Breast cancer risk with postmenopausal hormonal treatment. Hum Reprod Update 2005; 11: 545-60.
    • (2005) Hum Reprod Update , vol.11 , pp. 545-560
    • Collins, J.A.1    Blake, J.M.2    Crosignani, P.G.3
  • 247
    • 0035108951 scopus 로고    scopus 로고
    • Oestrogen receptor beta expression and depth of myometrial invasion in human endometrial cancer
    • Takama F, Kanuma T, Wang D, Kagami I, Mizunuma H. Oestrogen receptor beta expression and depth of myometrial invasion in human endometrial cancer. Br J Cancer 2001; 84: 545-9.
    • (2001) Br J Cancer , vol.84 , pp. 545-549
    • Takama, F.1    Kanuma, T.2    Wang, D.3    Kagami, I.4    Mizunuma, H.5
  • 248
    • 77953543011 scopus 로고    scopus 로고
    • Steroid receptors, HER2/neu and Ki-67, in endometrioid type of endometrial carcinoma: Correlation with conventional histomorphological features of prognosis
    • Chakravarty D, Gupta N, Goda JS, Srinivasan R, Patel FD, Dhaliwal L. Steroid receptors, HER2/neu and Ki-67, in endometrioid type of endometrial carcinoma: Correlation with conventional histomorphological features of prognosis. Acta Histochem 2010; 112: 355-63.
    • (2010) Acta Histochem , vol.112 , pp. 355-363
    • Chakravarty, D.1    Gupta, N.2    Goda, J.S.3    Srinivasan, R.4    Patel, F.D.5    Dhaliwal, L.6
  • 249
    • 35548960893 scopus 로고    scopus 로고
    • Prognostic significance of oestrogen receptor alpha (ERalpha) and beta (ERbeta), progesterone receptor A (PR-A) and B (PR-B) in endometrial carcinomas
    • Shabani N, Kuhn C, Kunze S, et al. Prognostic significance of oestrogen receptor alpha (ERalpha) and beta (ERbeta), progesterone receptor A (PR-A) and B (PR-B) in endometrial carcinomas. Eur J Cancer 2007; 43: 2434-44.
    • (2007) Eur J Cancer , vol.43 , pp. 2434-2444
    • Shabani, N.1    Kuhn, C.2    Kunze, S.3
  • 250
    • 60449115147 scopus 로고    scopus 로고
    • Expression of estrogen receptor-alpha and -beta and progesterone receptor-A and -B in a large cohort of patients with endometrioid endometrial cancer
    • Jongen V, Briët J, de Jong R, et al. Expression of estrogen receptor-alpha and -beta and progesterone receptor-A and -B in a large cohort of patients with endometrioid endometrial cancer. Gynecol Oncol 2009; 112: 537-42.
    • (2009) Gynecol Oncol , vol.112 , pp. 537-542
    • Jongen, V.1    Briët, J.2    de Jong, R.3
  • 251
    • 0042178374 scopus 로고    scopus 로고
    • The biological actions of estrogens on skin
    • Thornton,M.J. The biological actions of estrogens on skin. Exp Dermatol 2002; 11: 487-502.
    • (2002) Exp Dermatol , vol.11 , pp. 487-502
    • Thornton, M.J.1
  • 252
    • 77949405816 scopus 로고    scopus 로고
    • Incidence estimate of nonmelanoma skin cancer in the United States, 2006
    • Rogers HW, Weinstock MA, Harris AR, et al. Incidence estimate of nonmelanoma skin cancer in the United States, 2006. Arch Dermatol 2010; 146: 283-7.
    • (2010) Arch Dermatol , vol.146 , pp. 283-287
    • Rogers, H.W.1    Weinstock, M.A.2    Harris, A.R.3
  • 253
    • 39149140365 scopus 로고    scopus 로고
    • Non-melanoma skin cancer: Importance of gender, immunosuppressive status and vitamin D
    • Oberyszyn TM. Non-melanoma skin cancer: importance of gender, immunosuppressive status and vitamin D. Cancer Lett 2008; 261: 127-36.
    • (2008) Cancer Lett , vol.261 , pp. 127-136
    • Oberyszyn, T.M.1
  • 254
    • 0019784545 scopus 로고
    • Hormonal regulation of epidermal tumor development
    • Lupulescu A. Hormonal regulation of epidermal tumor development. J Invest Dermatol 1981; 77: 186-95.
    • (1981) J Invest Dermatol , vol.77 , pp. 186-195
    • Lupulescu, A.1
  • 255
    • 60149098270 scopus 로고    scopus 로고
    • Modulation of basal and squamous cell carcinoma by endogenous estrogen in mouse models of skin cancer
    • Mancuso M, Gallo D, Leonardi S, et al. Modulation of basal and squamous cell carcinoma by endogenous estrogen in mouse models of skin cancer. Carcinogenesis 2009; 30: 340-7.
    • (2009) Carcinogenesis , vol.30 , pp. 340-347
    • Mancuso, M.1    Gallo, D.2    Leonardi, S.3
  • 256
    • 33947326117 scopus 로고    scopus 로고
    • Estrogen receptors alpha and beta are inhibitory modifiers of Apcdependent tumorigenesis in the proximal colon of Min/+ mice
    • Cho NL, Javid SH, Carothers AM, Redston M, Bertagnolli MM. Estrogen receptors alpha and beta are inhibitory modifiers of Apcdependent tumorigenesis in the proximal colon of Min/+ mice. Cancer Res 2007; 67: 2366-72.
    • (2007) Cancer Res , vol.67 , pp. 2366-2372
    • Cho, N.L.1    Javid, S.H.2    Carothers, A.M.3    Redston, M.4    Bertagnolli, M.M.5
  • 257
    • 0035880957 scopus 로고    scopus 로고
    • Prognostic factors analysis of 17,600 melanoma patients: Validation of the American Joint Committee on Cancer melanoma staging system
    • Balch CM, Soong SJ, Gershenwald JE, et al. Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system. J Clin Oncol 2001; 19: 3622-34.
    • (2001) J Clin Oncol , vol.19 , pp. 3622-3634
    • Balch, C.M.1    Soong, S.J.2    Gershenwald, J.E.3
  • 258
    • 40149093090 scopus 로고    scopus 로고
    • Superior survival of females among 10,538 Dutch melanoma patients is independent of Breslow thickness, histologic type and tumor site
    • de Vries E, Nijsten TE, Visser O, et al. Superior survival of females among 10,538 Dutch melanoma patients is independent of Breslow thickness, histologic type and tumor site. Ann Oncol 2008; 19: 583-9.
    • (2008) Ann Oncol , vol.19 , pp. 583-589
    • de Vries, E.1    Nijsten, T.E.2    Visser, O.3
  • 259
    • 36049050338 scopus 로고    scopus 로고
    • Hormones, nevi, and melanoma: An approach to the patient
    • Driscoll MS, Grant-Kels JM. Hormones, nevi, and melanoma: an approach to the patient. J Am Acad Dermatol 2007; 57: 919-31.
    • (2007) J Am Acad Dermatol , vol.57 , pp. 919-931
    • Driscoll, M.S.1    Grant-Kels, J.M.2
  • 260
    • 43749094745 scopus 로고    scopus 로고
    • Melanoma in relation to reproductive and hormonal factors in women: Current review on controversial issues
    • Lens M, Bataille V. Melanoma in relation to reproductive and hormonal factors in women: current review on controversial issues. Cancer Causes Control 2008; 19: 437-42.
    • (2008) Cancer Causes Control , vol.19 , pp. 437-442
    • Lens, M.1    Bataille, V.2
  • 261
    • 60549100903 scopus 로고    scopus 로고
    • Estrogens, oral contraceptives and hormonal replacement therapy increase the incidence of cutaneous melanoma: A population-based case-control study
    • Koomen ER, Joosse A, Herings RM, Casparie MK, Guchelaar HJ, Nijsten T. Estrogens, oral contraceptives and hormonal replacement therapy increase the incidence of cutaneous melanoma: a population-based case-control study. Ann Oncol 2009; 20: 358-64.
    • (2009) Ann Oncol , vol.20 , pp. 358-364
    • Koomen, E.R.1    Joosse, A.2    Herings, R.M.3    Casparie, M.K.4    Guchelaar, H.J.5    Nijsten, T.6
  • 262
    • 0024243320 scopus 로고
    • Effect of 17 beta-estradiol on the growth of estrogen receptor-positive human melanoma in vitro and in athymic mice
    • Feucht KA, Walker MJ, Das Gupta TK, Beattie CW. Effect of 17 beta-estradiol on the growth of estrogen receptor-positive human melanoma in vitro and in athymic mice. Cancer Res 1988; 48: 7093-101.
    • (1988) Cancer Res , vol.48 , pp. 7093-7101
    • Feucht, K.A.1    Walker, M.J.2    Das, G.T.K.3    Beattie, C.W.4
  • 263
    • 0032788196 scopus 로고    scopus 로고
    • Investigation of female survival benefit in metastatic melanoma
    • Richardson B, Price A, Wagner M, et al. Investigation of female survival benefit in metastatic melanoma. Br J Cancer 1999; 80: 2025-33.
    • (1999) Br J Cancer , vol.80 , pp. 2025-2033
    • Richardson, B.1    Price, A.2    Wagner, M.3
  • 264
    • 0035542661 scopus 로고    scopus 로고
    • 17beta-estradiol, progesterone, and dihydrotestosterone suppress the growth of human melanoma by inhibiting interleukin-8 production
    • Kanda N, Watanabe S. 17beta-estradiol, progesterone, and dihydrotestosterone suppress the growth of human melanoma by inhibiting interleukin-8 production. J Invest Dermatol. 2001; 117: 274-83.
    • (2001) J Invest Dermatol , vol.117 , pp. 274-283
    • Kanda, N.1
  • 266
    • 58849129029 scopus 로고    scopus 로고
    • Estrogen receptor expression in cutaneous melanoma: A real-time reverse transcriptasepolymerase chain reaction and immunohistochemical study
    • de Giorgi V, Mavilia C, Massi D, et al. Estrogen receptor expression in cutaneous melanoma: a real-time reverse transcriptasepolymerase chain reaction and immunohistochemical study. Arch Dermatol 2009; 145: 30-6.
    • (2009) Arch Dermatol , vol.145 , pp. 30-36
    • de Giorgi, V.1    Mavilia, C.2    Massi, D.3
  • 267
    • 67650584040 scopus 로고    scopus 로고
    • 1975-2006, National Cancer Institute. Bethesda, MD, based on November 2008 SEER data submission, posted to the SEER web site
    • Horner MJ, Ries LAG, Krapcho M, et al (eds). SEER Cancer Statistics Review, 1975-2006, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2006/, based on November 2008 SEER data submission, posted to the SEER web site, 2009.
    • (2009) SEER Cancer Statistics Review
    • Horner, M.J.1    Ries, L.A.G.2    Krapcho, M.3
  • 268
    • 39249084652 scopus 로고    scopus 로고
    • Demographic, clinical, and treatment trends among women diagnosed with vulvar cancer in the United States
    • Stroup AM, Harlan LC, Trimble EL. Demographic, clinical, and treatment trends among women diagnosed with vulvar cancer in the United States. Gynecol Oncol 2008; 108: 577-83.
    • (2008) Gynecol Oncol , vol.108 , pp. 577-583
    • Stroup, A.M.1    Harlan, L.C.2    Trimble, E.L.3
  • 269
    • 38349159557 scopus 로고    scopus 로고
    • Differential expression of oestrogen receptor isoforms and androgen receptor in the normal vulva and vagina compared with vulval lichen sclerosus and chronic vaginitis
    • Taylor AH, Guzail M, Al-Azzawi F. Differential expression of oestrogen receptor isoforms and androgen receptor in the normal vulva and vagina compared with vulval lichen sclerosus and chronic vaginitis. Br J Dermatol 2008; 158: 319-28.
    • (2008) Br J Dermatol , vol.158 , pp. 319-328
    • Taylor, A.H.1    Guzail, M.2    Al-Azzawi, F.3
  • 270
    • 79951592109 scopus 로고    scopus 로고
    • Changes in the expression of Oestrogen Receptors and E-cadherin as molecular markers of progression from normal epithelium to invasive cancer in elderly patients with vulvar squamous cell carcinoma: A pilot study
    • Zannoni GF, Prisco Mg, Vellone VG, et al. Changes in the expression of Oestrogen Receptors and E-cadherin as molecular markers of progression from normal epithelium to invasive cancer in elderly patients with vulvar squamous cell carcinoma: a pilot study. Histopathology 2011; 58: 265-75.
    • (2011) Histopathology , vol.58 , pp. 265-275
    • Zannoni, G.F.1    Prisco, M.G.2    Vellone, V.G.3
  • 271
    • 81555214742 scopus 로고    scopus 로고
    • Cytoplasmic expression of Estrogen Receptor beta (ER) as a prognostic factor in vulvar squamous cell carcinoma in elderly women
    • Zannoni GF, Prisco MG, Vellone VG, et al. Cytoplasmic expression of Estrogen Receptor beta (ER) as a prognostic factor in vulvar squamous cell carcinoma in elderly women. Histopathology 2011; 59: 909-17.
    • (2011) Histopathology , vol.59 , pp. 909-917
    • Zannoni, G.F.1    Prisco, M.G.2    Vellone, V.G.3
  • 272
    • 33646568784 scopus 로고    scopus 로고
    • Patterns of cancer incidence, mortality, and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world
    • Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 2006; 24: 2137-50.
    • (2006) J Clin Oncol , vol.24 , pp. 2137-2150
    • Kamangar, F.1    Dores, G.M.2    Anderson, W.F.3
  • 273
    • 0003043603 scopus 로고    scopus 로고
    • Neoplasms of the central nervous system
    • In: DeVita VT Jr, Hellman S, Rosenberg SA, eds., 6th ed. Philadelphia, PA: Lippincott Williams & Wilkins
    • Levin VA, Leibel SA, Gutin PH. Neoplasms of the central nervous system. In: DeVita VT Jr, Hellman S, Rosenberg SA, eds. Cancer: Principles and Practice of Oncology. 6th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2001: 2100-60.
    • (2001) Cancer: Principles and Practice of Oncology , pp. 2100-2160
    • Levin, V.A.1    Leibel, S.A.2    Gutin, P.H.3
  • 274
    • 0027742617 scopus 로고
    • Primary tumors of the brain, cranial nerves and cranial meninges in Victoria. Australia, 1982-1990: Patterns of incidence and survival
    • Preston-Martin S, Staples M, Farrugia H, Giles G. Primary tumors of the brain, cranial nerves and cranial meninges in Victoria. Australia, 1982-1990: patterns of incidence and survival. Neuroepidemiology 1993; 12: 270-9.
    • (1993) Neuroepidemiology , vol.12 , pp. 270-279
    • Preston-Martin, S.1    Staples, M.2    Farrugia, H.3    Giles, G.4
  • 276
    • 0032513757 scopus 로고    scopus 로고
    • Influence of a child's sex on medulloblastoma outcome
    • Weil MD, Lamborn K, Edwards MS, Wara WM. Influence of a child's sex on medulloblastoma outcome. JAMA 1998; 279: 1474-6.
    • (1998) JAMA , vol.279 , pp. 1474-1476
    • Weil, M.D.1    Lamborn, K.2    Edwards, M.S.3    Wara, W.M.4
  • 277
    • 0035041023 scopus 로고    scopus 로고
    • Brain and other central nervous system tumors: Rates, trends, and epidemiology
    • Gurney JG, Kadan-Lottick N. Brain and other central nervous system tumors: rates, trends, and epidemiology. Curr Opin Oncol 2001; 13: 160-6.
    • (2001) Curr Opin Oncol , vol.13 , pp. 160-166
    • Gurney, J.G.1    Kadan-Lottick, N.2
  • 279
    • 14844300928 scopus 로고    scopus 로고
    • Reproductive and hormonal factors and risk of brain tumors in adult females
    • Hatch EE, Linet MS, Zhang J, et al. Reproductive and hormonal factors and risk of brain tumors in adult females. Int J Cancer 2005; 114: 797-805.
    • (2005) Int J Cancer , vol.114 , pp. 797-805
    • Hatch, E.E.1    Linet, M.S.2    Zhang, J.3
  • 280
    • 31844454641 scopus 로고    scopus 로고
    • Hormonal and reproductive factors and risk of glioma: A prospective cohort study
    • Silvera SA, Miller AB, Rohan TE. Hormonal and reproductive factors and risk of glioma: a prospective cohort study. Int J Cancer. 2006; 118: 1321-4.
    • (2006) Int J Cancer , vol.118 , pp. 1321-1324
    • Silvera, S.A.1    Miller, A.B.2    Rohan, T.E.3
  • 281
    • 33749008515 scopus 로고    scopus 로고
    • Swedish Interphone Study Group. Risk of brain tumors associated with exposure to exogenous female sex hormones
    • Wigertz A, Lönn S, Mathiesen T, Ahlbom A, Hall P, Feychting M; Swedish Interphone Study Group. Risk of brain tumors associated with exposure to exogenous female sex hormones. Am J Epidemiol. 2006; 164: 629-36.
    • (2006) Am J Epidemiol , vol.164 , pp. 629-636
    • Wigertz, A.1    Lönn, S.2    Mathiesen, T.3    Ahlbom, A.4    Hall, P.5    Feychting, M.6
  • 283
    • 58149394104 scopus 로고    scopus 로고
    • Gender affects survival for medulloblastoma only in older children and adults: A study from the Surveillance Epidemiology and End Results Registry
    • Curran EK, Sainani KL, Le GM, Propp JM, Fisher PG. Gender affects survival for medulloblastoma only in older children and adults: a study from the Surveillance Epidemiology and End Results Registry. Pediatr Blood Cancer 2009; 52: 60-4.
    • (2009) Pediatr Blood Cancer , vol.52 , pp. 60-64
    • Curran, E.K.1    Sainani, K.L.2    Le, G.M.3    Propp, J.M.4    Fisher, P.G.5
  • 285
    • 77952888513 scopus 로고    scopus 로고
    • Million Women Study Collaborators. Hormone replacement therapy and incidence of central nervous system tumours in the Million Women Study
    • Benson VS, Pirie K, Green J, et al. Million Women Study Collaborators. Hormone replacement therapy and incidence of central nervous system tumours in the Million Women Study. Int J Cancer 2010; 127: 1692-8.
    • (2010) Int J Cancer , vol.127 , pp. 1692-1698
    • Benson, V.S.1    Pirie, K.2    Green, J.3
  • 286
    • 67649644713 scopus 로고    scopus 로고
    • Blockade of estrogen receptor signaling inhibits growth and migration of medulloblastoma
    • Belcher SM, Ma X, Le HH. Blockade of estrogen receptor signaling inhibits growth and migration of medulloblastoma. Endocrinology 2009; 150: 1112-21.
    • (2009) Endocrinology , vol.150 , pp. 1112-1121
    • Belcher, S.M.1    Ma, X.2    Le, H.H.3
  • 287
    • 78249281351 scopus 로고    scopus 로고
    • Protective role of 17beta-estradiol on medulloblastoma development in Patched1 heterozygous mice
    • Mancuso M, Leonardi S, Ceccarelli M, et al. Protective role of 17beta-estradiol on medulloblastoma development in Patched1 heterozygous mice. Int J Cancer 2010; 127, 2749-57.
    • (2010) Int J Cancer , vol.127 , pp. 2749-2757
    • Mancuso, M.1    Leonardi, S.2    Ceccarelli, M.3
  • 288
    • 79959558098 scopus 로고    scopus 로고
    • The estrogen receptor beta agonist diarylpropionitrile (DPN) inhibits medulloblastoma development via anti-proliferative and pro-apototic pathways
    • Mancuso M, Leonardi S, Giardullo P, et al. The estrogen receptor beta agonist diarylpropionitrile (DPN) inhibits medulloblastoma development via anti-proliferative and pro-apototic pathways. Cancer Letters. 2011; 308: 197-202.
    • (2011) Cancer Letters , vol.308 , pp. 197-202
    • Mancuso, M.1    Leonardi, S.2    Giardullo, P.3
  • 289
    • 0033291826 scopus 로고    scopus 로고
    • Estrogen receptor beta mRNA expression in normal and adenomatous pituitaries
    • Gittoes NJ, McCabe CJ, Sheppard MC, Franklyn JA. Estrogen receptor beta mRNA expression in normal and adenomatous pituitaries. Pituitary 1999; 1: 99-104.
    • (1999) Pituitary , vol.1 , pp. 99-104
    • Gittoes, N.J.1    McCabe, C.J.2    Sheppard, M.C.3    Franklyn, J.A.4
  • 290
    • 0032994056 scopus 로고    scopus 로고
    • Expression of estrogen receptors alpha and beta in human meningiomas
    • Carroll RS, Zhang J, Black PM. Expression of estrogen receptors alpha and beta in human meningiomas. J Neurooncol 1999; 42: 109-16.
    • (1999) J Neurooncol , vol.42 , pp. 109-116
    • Carroll, R.S.1    Zhang, J.2    Black, P.M.3
  • 291
  • 292
    • 62149148829 scopus 로고    scopus 로고
    • Estrogen receptor betamediated nuclear interaction between IRS-1 and Rad51 inhibits homologous recombination directed DNA repair in medulloblastoma
    • Urbanska K, Pannizzo P, Lassak A, et al. Estrogen receptor betamediated nuclear interaction between IRS-1 and Rad51 inhibits homologous recombination directed DNA repair in medulloblastoma. J Cell Physiol 2009; 219: 92-401.
    • (2009) J Cell Physiol , vol.219 , pp. 92-401
    • Urbanska, K.1    Pannizzo, P.2    Lassak, A.3
  • 293
    • 33745050250 scopus 로고    scopus 로고
    • Estrogen receptor beta (ERbeta) protein expression correlates with BAG-1 and prognosis in brain glial tumours
    • Batistatou A, Kyzas PA, Goussia A, et al. Estrogen receptor beta (ERbeta) protein expression correlates with BAG-1 and prognosis in brain glial tumours. J Neurooncol 2006; 77: 17-23.
    • (2006) J Neurooncol , vol.77 , pp. 17-23
    • Batistatou, A.1    Kyzas, P.A.2    Goussia, A.3
  • 295
    • 0023853696 scopus 로고
    • Synchronous bilateral primary germ cell tumors in patient receiving estrogen therapy
    • Hem E, Attramadal A, and Tveter KJ. Synchronous bilateral primary germ cell tumors in patient receiving estrogen therapy. Urology 1988; 31: 70-71.
    • (1988) Urology , vol.31 , pp. 70-71
    • Hem, E.1    Attramadal, A.2    Tveter, K.J.3
  • 296
    • 0037121116 scopus 로고    scopus 로고
    • Gynecomastia and risk for malignant tum
    • Olsson HL, Bladstrom A, and Alm P. Gynecomastia and risk for malignant tum. BMC Cancer 2002; 2: 26.
    • (2002) BMC Cancer , vol.2 , pp. 26
    • Olsson, H.L.1    Bladstrom, A.2    Alm, P.3
  • 298
    • 0029688899 scopus 로고    scopus 로고
    • Hormonal factors in carcinogenesis of the prostate and testis in humans and in animal models
    • Bosland MC. Hormonal factors in carcinogenesis of the prostate and testis in humans and in animal models. Prog Clin Biol Res 1996; 394: 309-52.
    • (1996) Prog Clin Biol Res , vol.394 , pp. 309-352
    • Bosland, M.C.1
  • 299
    • 38549140747 scopus 로고    scopus 로고
    • Estrogens promote human testicular germ cell cancer through a membrane-mediated activation of extracellular regulated kinase and protein kinase A
    • Bouskine A, Nebout M, Mograbi B, Brücker-Davis F, Roger C, Fenichel P. Estrogens promote human testicular germ cell cancer through a membrane-mediated activation of extracellular regulated kinase and protein kinase A. Endocrinology 2008; 149: 565-73.
    • (2008) Endocrinology , vol.149 , pp. 565-573
    • Bouskine, A.1    Nebout, M.2    Mograbi, B.3    Brücker-Davis, F.4    Roger, C.5    Fenichel, P.6
  • 300
    • 23844533410 scopus 로고    scopus 로고
    • Estrogen-induced growth inhibition of human seminoma cells expressing estrogen receptor beta and aromatase
    • Roger C, Lambard S, Bouskine A, et al. Estrogen-induced growth inhibition of human seminoma cells expressing estrogen receptor beta and aromatase. J Mol Endocrinol 2005; 35: 191-9.
    • (2005) J Mol Endocrinol , vol.35 , pp. 191-199
    • Roger, C.1    Lambard, S.2    Bouskine, A.3
  • 301
    • 0034965612 scopus 로고    scopus 로고
    • Localization of oestrogen receptors alpha and beta in human testis
    • Mäkinen S, Mäkelä S, Weihua Z, et al. Localization of oestrogen receptors alpha and beta in human testis. Mol Hum Reprod 2001; 7: 497-503.
    • (2001) Mol Hum Reprod , vol.7 , pp. 497-503
    • Mäkinen, S.1    Mäkelä, S.2    Weihua, Z.3
  • 302
    • 0141925962 scopus 로고    scopus 로고
    • Estrogen receptor-beta expression in human testicular germ cell tumors
    • Pais V, Leav I, Lau KM, Jiang Z, Ho SM. Estrogen receptor-beta expression in human testicular germ cell tumors. Clin Cancer Res. 2003; 9: 4475-82.
    • (2003) Clin Cancer Res , vol.9 , pp. 4475-4482
    • Pais, V.1    Leav, I.2    Lau, K.M.3    Jiang, Z.4    Ho, S.M.5
  • 303
    • 0348165951 scopus 로고    scopus 로고
    • Down-regulation of estrogen receptor beta and transcriptional coregulator SNURF/RNF4 in testicular germ cell cancer
    • Hirvonen-Santti SJ, Rannikko A, Santti H, et al. Down-regulation of estrogen receptor beta and transcriptional coregulator SNURF/RNF4 in testicular germ cell cancer. Eur Urol 2003; 44: 742-7.
    • (2003) Eur Urol , vol.44 , pp. 742-747
    • Hirvonen-Santti, S.J.1    Rannikko, A.2    Santti, H.3
  • 304
    • 67649637303 scopus 로고    scopus 로고
    • Identification of ERbeta1 and ERbeta2 in human seminoma, in embryonal carcinoma and in their adjacent intratubular germ cell neoplasia
    • Jun
    • Rago V, Romeo F, Giordano F, Ferraro A, Andò S, Carpino A. Identification of ERbeta1 and ERbeta2 in human seminoma, in embryonal carcinoma and in their adjacent intratubular germ cell neoplasia. Reprod Biol Endocrinol 2009 Jun 3; 7: 56.
    • (2009) Reprod Biol Endocrinol , vol.7 , Issue.56 , pp. 3
    • Rago, V.1    Romeo, F.2    Giordano, F.3    Ferraro, A.4    Andò, S.5    Carpino, A.6
  • 305
    • 0035935731 scopus 로고    scopus 로고
    • Estrogen receptor-beta potency-selective ligands: Structure-activityrelationship studies of diarylpropionitriles and their acetylene and polar analogues
    • Meyers MJ, Sun J, Carlson KE, et al. Estrogen receptor-beta potency-selective ligands: structure-activityrelationship studies of diarylpropionitriles and their acetylene and polar analogues. J Med Chem 2001; 44: 4230-51.
    • (2001) J Med Chem , vol.44 , pp. 4230-4251
    • Meyers, M.J.1    Sun, J.2    Carlson, K.E.3
  • 307
    • 67650882238 scopus 로고    scopus 로고
    • Drug and cell type-specific regulation of genes with different classes of estrogen receptor betaselective agonists
    • Paruthiyil S, Cvoro A, Zhao X, et al. Drug and cell type-specific regulation of genes with different classes of estrogen receptor betaselective agonists. PLoS One 2009 Jul 17; 4(7): e6271.
    • (2009) PLoS One , vol.4 , Issue.7
    • Paruthiyil, S.1    Cvoro, A.2    Zhao, X.3
  • 308
    • 47249138273 scopus 로고    scopus 로고
    • Selective estrogen receptor modulator medicinal chemistry at Merck
    • Review
    • Blizzard TA. Selective estrogen receptor modulator medicinal chemistry at Merck. A review.Curr Top Med Chem 2008; 8: 792-812. Review.
    • (2008) A Review.Curr Top Med Chem , vol.8 , pp. 792-812
    • Blizzard, T.A.1
  • 309
    • 77956102054 scopus 로고    scopus 로고
    • Minireview: Estrogen receptor-beta: Mechanistic insights from recent studies
    • Deroo BJ, Buensuceso AV. Minireview: Estrogen receptor-beta: mechanistic insights from recent studies. Mol Endocrinol. 2010; 24: 1703-14.
    • (2010) Mol Endocrinol , vol.24 , pp. 1703-1714
    • Deroo, B.J.1    Buensuceso, A.V.2
  • 310
    • 78650446029 scopus 로고    scopus 로고
    • Estrogen receptors: Therapies targeted to receptor subtypes
    • Review
    • Nilsson S, Gustafsson JÅ. Estrogen receptors: therapies targeted to receptor subtypes. Clin Pharmacol Ther 2011; 89: 44-55. Review.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 44-55
    • Nilsson, S.1    Gustafsson, J.A.2
  • 311
    • 78649804890 scopus 로고    scopus 로고
    • Efficacy and safety of a selective estrogen receptor agonist, ERB-041, in patients with rheumatoid arthritis: A 12-week, randomized, placebo-controlled, phase II study
    • Roman-Blas JA, Castañeda S, Cutolo M, Herrero-Beaumont G. Efficacy and safety of a selective estrogen receptor agonist, ERB-041, in patients with rheumatoid arthritis: a 12-week, randomized, placebo-controlled, phase II study. Arthritis Care Res (Hoboken). 2010; 62: 1588-93.
    • (2010) Arthritis Care Res (Hoboken) , vol.62 , pp. 1588-1593
    • Roman-Blas, J.A.1    Castañeda, S.2    Cutolo, M.3    Herrero-Beaumont, G.4
  • 312
    • 77953497158 scopus 로고    scopus 로고
    • Lesson learned from nature for the development of novel anti-cancer agents: Implication of isoflavone, curcumin, and their synthetic analogs
    • Sarkar FH, Li Y, Wang Z, Padhye S. Lesson learned from nature for the development of novel anti-cancer agents: implication of isoflavone, curcumin, and their synthetic analogs. Curr Pharm Des 2010; 16: 1801-12.
    • (2010) Curr Pharm Des , vol.16 , pp. 1801-1812
    • Sarkar, F.H.1    Li, Y.2    Wang, Z.3    Padhye, S.4
  • 313
    • 77954584837 scopus 로고    scopus 로고
    • Estrogen receptor beta binds to and regulates three distinct classes of target genes
    • Vivar OI, Zhao X, Saunier EF, et al. Estrogen receptor beta binds to and regulates three distinct classes of target genes. J Biol Chem 2010; 285: 22059-66.
    • (2010) J Biol Chem , vol.285 , pp. 22059-22066
    • Vivar, O.I.1    Zhao, X.2    Saunier, E.F.3
  • 314
    • 0037025323 scopus 로고    scopus 로고
    • Opposing action of estrogen receptors alpha and beta on cyclin D1 gene expression
    • Liu MM, Albanese C, Anderson CM, et al. Opposing action of estrogen receptors alpha and beta on cyclin D1 gene expression. J Biol Chem 2002; 277: 24353-60.
    • (2002) J Biol Chem , vol.277 , pp. 24353-24360
    • Liu, M.M.1    Albanese, C.2    Anderson, C.M.3
  • 315
    • 14744283561 scopus 로고    scopus 로고
    • Survival versus apoptotic 17beta-estradiol effect: Role of ER alpha and ER beta activated non-genomic signaling
    • Acconcia F, Totta P, Ogawa S, et al. Survival versus apoptotic 17beta-estradiol effect: role of ER alpha and ER beta activated non-genomic signaling. J Cell Physiol 2005; 203: 193-201.
    • (2005) J Cell Physiol , vol.203 , pp. 193-201
    • Acconcia, F.1    Totta, P.2    Ogawa, S.3
  • 316
    • 0242710183 scopus 로고    scopus 로고
    • Update on animal models developed for analyses of estrogen receptor biological activity
    • Korach KS, Emmen JM, Walker VR, et al. Update on animal models developed for analyses of estrogen receptor biological activity. J Steroid Biochem Mol Biol 2003; 86: 387-91.
    • (2003) J Steroid Biochem Mol Biol , vol.86 , pp. 387-391
    • Korach, K.S.1    Emmen, J.M.2    Walker, V.R.3
  • 317
    • 1642332240 scopus 로고    scopus 로고
    • Estrogen signaling: A subtle balance between ER alpha and ER beta
    • Review
    • Matthews J, Gustafsson JA. Estrogen signaling: a subtle balance between ER alpha and ER beta. Mol Interv 2003; 3: 281-92. Review.
    • (2003) Mol Interv , vol.3 , pp. 281-292
    • Matthews, J.1    Gustafsson, J.A.2
  • 318
    • 71849103610 scopus 로고    scopus 로고
    • Unliganded estrogen receptor-beta regulation of genes is inhibited by tamoxifen
    • Levy N, Paruthiyil S, Zhao X, et al. Unliganded estrogen receptor-beta regulation of genes is inhibited by tamoxifen. Mol Cell Endocrinol 2010; 315: 201-7.
    • (2010) Mol Cell Endocrinol , vol.315 , pp. 201-207
    • Levy, N.1    Paruthiyil, S.2    Zhao, X.3
  • 319
    • 77952302285 scopus 로고    scopus 로고
    • The role of estrogen receptor beta (ERbeta) in malignant diseases--a new potential target for antiproliferative drugs in prevention and treatment of cancer
    • Review
    • Warner M, Gustafsson JA. The role of estrogen receptor beta (ERbeta) in malignant diseases--a new potential target for antiproliferative drugs in prevention and treatment of cancer. Biochem Biophys Res Commun 2010; 396: 63-6. Review.
    • (2010) Biochem Biophys Res Commun , vol.396 , pp. 63-66
    • Warner, M.1    Gustafsson, J.A.2
  • 320
    • 4944246588 scopus 로고    scopus 로고
    • Loss of ER-beta expression as a common step in estrogen-dependent tumor progression
    • Review
    • Bardin A, Boulle N, Lazennec G, Vignon F, Pujol P. Loss of ER-beta expression as a common step in estrogen-dependent tumor progression. Endocr Relat Cancer 2004; 11: 537-51. Review.
    • (2004) Endocr Relat Cancer , vol.11 , pp. 537-551
    • Bardin, A.1    Boulle, N.2    Lazennec, G.3    Vignon, F.4    Pujol, P.5
  • 321
    • 70849093259 scopus 로고    scopus 로고
    • Regulation of estrogen receptor beta activity and implications in health and disease
    • Swedenborg E, Power KA, Cai W, Pongratz I, Rüegg J. Regulation of estrogen receptor beta activity and implications in health and disease. Cell Mol Life Sci 2009; 66: 3873-94.
    • (2009) Cell Mol Life Sci , vol.66 , pp. 3873-3894
    • Swedenborg, E.1    Power, K.A.2    Cai, W.3    Pongratz, I.4    Rüegg, J.5
  • 322
    • 33745683516 scopus 로고    scopus 로고
    • Progress in chemoprevention drug development: The promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer-a plan to move forward. Clin
    • Review
    • Kelloff GJ, Lippman SM, Dannenberg AJ et al. Progress in chemoprevention drug development: the promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer-a plan to move forward. Clin. Cancer Res 2006; 12; 3661-97. Review.
    • (2006) Cancer Res , vol.12 , pp. 3661-3697
    • Kelloff, G.J.1    Lippman, S.M.2    Dannenberg, A.J.3
  • 323
    • 0034735859 scopus 로고    scopus 로고
    • Molecular mechanisms of estrogen action: Selective ligands and receptor pharmacology
    • Review
    • Katzenellenbogen BS, Choi I, Delage-Mourroux R, et al. Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology. J Steroid Biochem Mol Biol 2000; 74: 279-85. Review.
    • (2000) J Steroid Biochem Mol Biol , vol.74 , pp. 279-285
    • Katzenellenbogen, B.S.1    Choi, I.2    Delage-Mourroux, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.