메뉴 건너뛰기




Volumn 288, Issue 3 51-3, 2005, Pages

Comparative effects of DHEA vs. testosterone, dihydrotestosterone, and estradiol on proliferation and gene expression in human LNCaP prostate cancer cells

Author keywords

Androgen receptor; Dehydroepiandrosterone; Estrogen receptor ; Insulin like growth factor axis; Lymph node derived cancer of prostate; Prostate specific antigen

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANDROSTANOLONE; ESTRADIOL; ESTROGEN; MESSENGER RNA; PRASTERONE; PROSTATE SPECIFIC ANTIGEN; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN BINDING PROTEIN 5; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TESTOSTERONE;

EID: 13844262629     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00454.2004     Document Type: Article
Times cited : (107)

References (60)
  • 1
    • 1642277861 scopus 로고    scopus 로고
    • Pharmacokinetics of dehydroepiandrosterone and its metabolites after long-term daily oral administration to healthy young men
    • Acacio BD, Stanczyk FZ, Mullin P, Saadat P, Jafarian N, and Sokol RZ. Pharmacokinetics of dehydroepiandrosterone and its metabolites after long-term daily oral administration to healthy young men. Fertil Steril 81: 595-604, 2004.
    • (2004) Fertil Steril , vol.81 , pp. 595-604
    • Acacio, B.D.1    Stanczyk, F.Z.2    Mullin, P.3    Saadat, P.4    Jafarian, N.5    Sokol, R.Z.6
  • 2
    • 0033906634 scopus 로고    scopus 로고
    • Structure and function of the type 1 insulin-like growth factor receptor
    • Adams TE, Epa VC, Garrett TP, and Ward CW. Structure and function of the type 1 insulin-like growth factor receptor. Cell Mol Life Sci 57: 1050-1093, 2000.
    • (2000) Cell Mol Life Sci , vol.57 , pp. 1050-1093
    • Adams, T.E.1    Epa, V.C.2    Garrett, T.P.3    Ward, C.W.4
  • 3
    • 13844278425 scopus 로고    scopus 로고
    • Dehydrodepiandrosterone
    • edited by Coates P, Blackman MR, Cragg G, Levine M, Moss J, and White J. New York: Marcel Dekker. In press
    • Alesci S, Manoli I, and Blackman MR. Dehydrodepiandrosterone. In: Encyclopedia of Dietary Supplements, edited by Coates P, Blackman MR, Cragg G, Levine M, Moss J, and White J. New York: Marcel Dekker. In press.
    • Encyclopedia of Dietary Supplements
    • Alesci, S.1    Manoli, I.2    Blackman, M.R.3
  • 4
    • 0036144615 scopus 로고    scopus 로고
    • Effect of normal endometrial stroma on growth and differentiation in Ishikawa endometrial adenocarcinoma cells
    • Arnold JT, Lessey BA, Seppala M, and Kaufman DG. Effect of normal endometrial stroma on growth and differentiation in Ishikawa endometrial adenocarcinoma cells. Cancer Res 62: 79-88, 2002.
    • (2002) Cancer Res , vol.62 , pp. 79-88
    • Arnold, J.T.1    Lessey, B.A.2    Seppala, M.3    Kaufman, D.G.4
  • 6
    • 0023822249 scopus 로고
    • Adrenal precursor C19 steroids are potent stimulators of growth of androgen-sensitive mouse mammary carcinoma Shionogi cells in vitro
    • Begin D, Luthy IA, and Labrie F. Adrenal precursor C19 steroids are potent stimulators of growth of androgen-sensitive mouse mammary carcinoma Shionogi cells in vitro. Mol Cell Endocrinol 58: 213-219, 1988.
    • (1988) Mol Cell Endocrinol , vol.58 , pp. 213-219
    • Begin, D.1    Luthy, I.A.2    Labrie, F.3
  • 7
    • 0742324418 scopus 로고    scopus 로고
    • Androgen receptor regulation by physiological concentrations of the isoflavonoid genistein in androgen-dependent LNCaP cells is mediated by estrogen receptor beta
    • Bektic J, Berger AP, Pfeil K, Dobler G, Bartsch G, and Klocker H. Androgen receptor regulation by physiological concentrations of the isoflavonoid genistein in androgen-dependent LNCaP cells is mediated by estrogen receptor beta. Eur Urol 45: 245-251, 2004.
    • (2004) Eur Urol , vol.45 , pp. 245-251
    • Bektic, J.1    Berger, A.P.2    Pfeil, K.3    Dobler, G.4    Bartsch, G.5    Klocker, H.6
  • 8
    • 0031465938 scopus 로고    scopus 로고
    • Dehydroepiandrosterone stimulates the estrogen response element
    • Bruder JM, Sobek L, and Oettel M. Dehydroepiandrosterone stimulates the estrogen response element. J Steroid Biochem Mol Biol 62: 461-466, 1997.
    • (1997) J Steroid Biochem Mol Biol , vol.62 , pp. 461-466
    • Bruder, J.M.1    Sobek, L.2    Oettel, M.3
  • 12
    • 0033613201 scopus 로고    scopus 로고
    • Suppression of delta(5)-androstenediol-induced androgen receptor transactivation by selective steroids in human prostate cancer cells
    • Chang HC, Miyamoto H, Marwah P, Lardy H, Yeh S, Huang KE, and Chang C. Suppression of delta(5)-androstenediol-induced androgen receptor transactivation by selective steroids in human prostate cancer cells. Proc Natl Acad Sci USA 96: 11173-11177, 1999.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11173-11177
    • Chang, H.C.1    Miyamoto, H.2    Marwah, P.3    Lardy, H.4    Yeh, S.5    Huang, K.E.6    Chang, C.7
  • 13
    • 0028048974 scopus 로고
    • Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease
    • Cohen P, Peehl DM, Graves HC, and Rosenfeld RG. Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease. J Endocrinol 142: 407-415, 1994.
    • (1994) J Endocrinol , vol.142 , pp. 407-415
    • Cohen, P.1    Peehl, D.M.2    Graves, H.C.3    Rosenfeld, R.G.4
  • 16
    • 0027599897 scopus 로고
    • The relationship of serum dehydroepiandrosterone and its sulfate to subsequent cancer of the prostate
    • Comstock GW, Gordon GB, and Hsing AW. The relationship of serum dehydroepiandrosterone and its sulfate to subsequent cancer of the prostate. Cancer Epidemiol Biomarkers Prev 1: 219-221, 1993.
    • (1993) Cancer Epidemiol Biomarkers Prev , vol.1 , pp. 219-221
    • Comstock, G.W.1    Gordon, G.B.2    Hsing, A.W.3
  • 17
    • 0036554817 scopus 로고    scopus 로고
    • Inhibition of androgen-independent growth of prostate cancer xenografts by 17beta-estradiol
    • Corey E, Quinn JE, Emond MJ, Buhler KR, Brown LG, and Vessella RL. Inhibition of androgen-independent growth of prostate cancer xenografts by 17beta-estradiol. Clin Cancer Res 8: 1003-1007, 2002.
    • (2002) Clin Cancer Res , vol.8 , pp. 1003-1007
    • Corey, E.1    Quinn, J.E.2    Emond, M.J.3    Buhler, K.R.4    Brown, L.G.5    Vessella, R.L.6
  • 19
  • 20
    • 0026091197 scopus 로고
    • Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells
    • De Launoit Y, Veilleux R, Dufour M, Simard J, and Labrie F. Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells. Cancer Res 51: 5165-5170, 1991.
    • (1991) Cancer Res , vol.51 , pp. 5165-5170
    • De Launoit, Y.1    Veilleux, R.2    Dufour, M.3    Simard, J.4    Labrie, F.5
  • 21
    • 0032914659 scopus 로고    scopus 로고
    • Localization of type 5 17beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase, and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry
    • El-Alfy M, Luu-The V, Huang XF, Berger L, Labrie F, and Pelletier G. Localization of type 5 17beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase, and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry. Endocrinology 140: 1481-1491, 1999.
    • (1999) Endocrinology , vol.140 , pp. 1481-1491
    • El-Alfy, M.1    Luu-The, V.2    Huang, X.F.3    Berger, L.4    Labrie, F.5    Pelletier, G.6
  • 22
    • 0022389768 scopus 로고
    • Rationale for blockade of adrenal as well as testicular androgens in the treatment of advanced prostate cancer
    • Geller J. Rationale for blockade of adrenal as well as testicular androgens in the treatment of advanced prostate cancer. Semin Oncol 12: 28-35, 1985.
    • (1985) Semin Oncol , vol.12 , pp. 28-35
    • Geller, J.1
  • 23
    • 0033237659 scopus 로고    scopus 로고
    • Induction of 3beta-hydroxysteroid dehydrogenase/isomerase type 1 expression by interleukin-4 in human normal prostate epithelial cells, immortalized keratinocytes, colon, and cervix cancer cell lines
    • Gingras S and Simard J. Induction of 3beta-hydroxysteroid dehydrogenase/isomerase type 1 expression by interleukin-4 in human normal prostate epithelial cells, immortalized keratinocytes, colon, and cervix cancer cell lines. Endocrinology 140: 4573-4584,. 1999.
    • (1999) Endocrinology , vol.140 , pp. 4573-4584
    • Gingras, S.1    Simard, J.2
  • 24
    • 0033780655 scopus 로고    scopus 로고
    • Insulin-like growth factor II and androgen receptor expression in the prostate
    • Gnanapragasam VJ, McCahy PJ, Neal DE, and Robson CN. Insulin-like growth factor II and androgen receptor expression in the prostate. BJU Int 86: 731-735, 2000.
    • (2000) BJU Int , vol.86 , pp. 731-735
    • Gnanapragasam, V.J.1    McCahy, P.J.2    Neal, D.E.3    Robson, C.N.4
  • 25
    • 0032863546 scopus 로고    scopus 로고
    • Androgens decrease and retinoids increase the expression of insulin-like growth factor-binding protein-3 in LNCaP prostatic adenocarcinoma cells
    • Goossens K, Esquenet M, Swinnen JV, Manin M, Rombauts W, and Verhoeven G. Androgens decrease and retinoids increase the expression of insulin-like growth factor-binding protein-3 in LNCaP prostatic adenocarcinoma cells. Mol Cell Endocrinol 155: 9-18, 1999.
    • (1999) Mol Cell Endocrinol , vol.155 , pp. 9-18
    • Goossens, K.1    Esquenet, M.2    Swinnen, J.V.3    Manin, M.4    Rombauts, W.5    Verhoeven, G.6
  • 26
    • 0033306866 scopus 로고    scopus 로고
    • Androgen receptor up-regulates insulin-like growth factor binding protein-5 (IGFBP-5) expression in a human prostate cancer xenograft
    • Gregory CW, Kim D, Ye P, D'Ercole AJ, Pretlow TG, Mohler JL, and French FS. Androgen receptor up-regulates insulin-like growth factor binding protein-5 (IGFBP-5) expression in a human prostate cancer xenograft. Endocrinology 140: 2372-2381, 1999.
    • (1999) Endocrinology , vol.140 , pp. 2372-2381
    • Gregory, C.W.1    Kim, D.2    Ye, P.3    D'Ercole, A.J.4    Pretlow, T.G.5    Mohler, J.L.6    French, F.S.7
  • 27
    • 0034527640 scopus 로고    scopus 로고
    • Serum levels of insulin-like growth factor I (IGF-I), IGF-II, IGF-binding protein-3, and prostate-specific antigen as predictors of clinical prostate cancer
    • Harman SM, Metter EJ, Blackman MR, Landis PK, and Carter HB. Serum levels of insulin-like growth factor I (IGF-I), IGF-II, IGF-binding protein-3, and prostate-specific antigen as predictors of clinical prostate cancer. J Clin Endocrinol Metab 85: 4258-4265, 2000.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4258-4265
    • Harman, S.M.1    Metter, E.J.2    Blackman, M.R.3    Landis, P.K.4    Carter, H.B.5
  • 30
    • 0021749906 scopus 로고
    • The aging ACI/Seg versus Copenhagen male rat as a model system for the study of prostatic carcinogenesis
    • Isaacs JT. The aging ACI/Seg versus Copenhagen male rat as a model system for the study of prostatic carcinogenesis. Cancer Res 44: 5785-5796, 1984.
    • (1984) Cancer Res , vol.44 , pp. 5785-5796
    • Isaacs, J.T.1
  • 31
    • 0024245885 scopus 로고
    • Androgens, adrenal androgen precursors, and their metabolism in untreated primary tumors and lymph node metastases of human prostatic cancer
    • Klein H, Bressel M, Kastendieck H, and Voigt KD. Androgens, adrenal androgen precursors, and their metabolism in untreated primary tumors and lymph node metastases of human prostatic cancer. Am J Clin Oncol 11, Suppl 2: S30-S36, 1988.
    • (1988) Am J Clin Oncol , vol.11 , Issue.2 SUPPL.
    • Klein, H.1    Bressel, M.2    Kastendieck, H.3    Voigt, K.D.4
  • 32
    • 0035094654 scopus 로고    scopus 로고
    • Adrenal steroids in human prostatic cancer cell lines
    • Koh E, Kanaya J, and Namiki M. Adrenal steroids in human prostatic cancer cell lines. Arch Androl 46: 117-125, 2001.
    • (2001) Arch Androl , vol.46 , pp. 117-125
    • Koh, E.1    Kanaya, J.2    Namiki, M.3
  • 33
    • 0032076761 scopus 로고    scopus 로고
    • DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: Its role during aging
    • Labrie F, Belanger A, Luu-The V, Labrie C, Simard J, Cusan L, Gomez JL, and Candas B. DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: its role during aging. Steroids 63: 322-328, 1998.
    • (1998) Steroids , vol.63 , pp. 322-328
    • Labrie, F.1    Belanger, A.2    Luu-The, V.3    Labrie, C.4    Simard, J.5    Cusan, L.6    Gomez, J.L.7    Candas, B.8
  • 34
    • 0034895297 scopus 로고    scopus 로고
    • DHEA and its transformation into androgens and estrogens in peripheral target tissues: Intracrinology
    • Labrie F, Luu-The V, Labrie C, and Simard J. DHEA and its transformation into androgens and estrogens in peripheral target tissues: intracrinology. Front Neuroendocrinol 22: 185-212, 2001.
    • (2001) Front Neuroendocrinol , vol.22 , pp. 185-212
    • Labrie, F.1    Luu-The, V.2    Labrie, C.3    Simard, J.4
  • 35
    • 0035266404 scopus 로고    scopus 로고
    • Evaluation of androgen, estrogen (ER alpha and ER beta), and progesterone receptor expression in human prostate cancer by real-time quantitative reverse transcription-polymerase chain reaction assays
    • Latil A, Bieche I, Vidaud D, Lidereau R, Berthon P, Cussenot O, and Vidaud M. Evaluation of androgen, estrogen (ER alpha and ER beta), and progesterone receptor expression in human prostate cancer by real-time quantitative reverse transcription-polymerase chain reaction assays. Cancer Res 61: 1919-1926, 2001.
    • (2001) Cancer Res , vol.61 , pp. 1919-1926
    • Latil, A.1    Bieche, I.2    Vidaud, D.3    Lidereau, R.4    Berthon, P.5    Cussenot, O.6    Vidaud, M.7
  • 36
    • 0033214658 scopus 로고    scopus 로고
    • Adrenal androgens stimulate the proliferation of breast cancer cells as direct activators of estrogen receptor alpha
    • Maggiolini M, Donze O, Jeannin E, Ando S, and Picard D. Adrenal androgens stimulate the proliferation of breast cancer cells as direct activators of estrogen receptor alpha. Cancer Res 59: 4864-4869, 1999.
    • (1999) Cancer Res , vol.59 , pp. 4864-4869
    • Maggiolini, M.1    Donze, O.2    Jeannin, E.3    Ando, S.4    Picard, D.5
  • 38
    • 0027932285 scopus 로고
    • Widespread tissue distribution of steroid sulfatase, 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD), 17 beta-HSD 5 alpha-reductase and aromatase activities in the rhesus monkey
    • Martel C, Meiner MH, Gagne D, Simard J, and Labrie F. Widespread tissue distribution of steroid sulfatase, 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD), 17 beta-HSD 5 alpha-reductase and aromatase activities in the rhesus monkey. Mol Cell Endocrinol 104: 103-111, 1994.
    • (1994) Mol Cell Endocrinol , vol.104 , pp. 103-111
    • Martel, C.1    Meiner, M.H.2    Gagne, D.3    Simard, J.4    Labrie, F.5
  • 40
    • 0032732061 scopus 로고    scopus 로고
    • Are the hormones of youth carcinogenic?
    • Martin-Du Pan RC. [Are the hormones of youth carcinogenic?] Ann Endocrinol (Paris) 60: 392-397, 1999.
    • (1999) Ann Endocrinol (Paris) , vol.60 , pp. 392-397
    • Martin-Du Pan, R.C.1
  • 41
    • 0031594509 scopus 로고    scopus 로고
    • Presence of 5alpha-reductase isozymes and aromatase in human prostate cancer cells and in benign prostate hyperplastic tissue
    • Negri-Cesi P, Poletti A, Colciago A, Magni P, Martini P, and Motta M. Presence of 5alpha-reductase isozymes and aromatase in human prostate cancer cells and in benign prostate hyperplastic tissue. Prostate 34: 283-291, 1998.
    • (1998) Prostate , vol.34 , pp. 283-291
    • Negri-Cesi, P.1    Poletti, A.2    Colciago, A.3    Magni, P.4    Martini, P.5    Motta, M.6
  • 42
    • 0035881876 scopus 로고    scopus 로고
    • In vivo progression of LAPC-9 and LNCaP prostate cancer models to androgen independence is associated with increased expression of insulin-like growth factor I (IGF-I) and IGF-I receptor (IGF-IR)
    • Nickerson T, Chang F, Lorimer D, Smeekens SP, Sawyers CL, and . Pollak M. In vivo progression of LAPC-9 and LNCaP prostate cancer models to androgen independence is associated with increased expression of insulin-like growth factor I (IGF-I) and IGF-I receptor (IGF-IR). Cancer Res 61: 6276-6280, 2001.
    • (2001) Cancer Res , vol.61 , pp. 6276-6280
    • Nickerson, T.1    Chang, F.2    Lorimer, D.3    Smeekens, S.P.4    Sawyers, C.L.5    Pollak, M.6
  • 43
    • 0023032056 scopus 로고
    • The inability of adrenal androgens to stimulate the adult human prostate: An autopsy evaluation of men with hypogonadotropic hypogonadism and panhypopituitarism
    • Oesterling JE, Epstein JI, and Walsh PC. The inability of adrenal androgens to stimulate the adult human prostate: an autopsy evaluation of men with hypogonadotropic hypogonadism and panhypopituitarism. J Urol 136: 1030-1034, 1986.
    • (1986) J Urol , vol.136 , pp. 1030-1034
    • Oesterling, J.E.1    Epstein, J.I.2    Walsh, P.C.3
  • 44
    • 0026629845 scopus 로고
    • Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men
    • Orentreich N, Brind JL, Vogelman JH, Andres R, and Baldwin H. Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men. J Clin Endocrinol Metab 75: 1002-1004, 1992.
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 1002-1004
    • Orentreich, N.1    Brind, J.L.2    Vogelman, J.H.3    Andres, R.4    Baldwin, H.5
  • 45
    • 0029439502 scopus 로고
    • The insulin-like growth factor system in the prostate
    • Peehl DM, Cohen P, and Rosenfeld RG. The insulin-like growth factor system in the prostate. World J Urol 13: 306-311, 1995.
    • (1995) World J Urol , vol.13 , pp. 306-311
    • Peehl, D.M.1    Cohen, P.2    Rosenfeld, R.G.3
  • 46
    • 0016614316 scopus 로고
    • Interaction of delta-5-androstene-3beta, 17beta-diol with estradiol and dinydrotestosterone receptors in human myometrial and mammary cancer tissue
    • Poortman J, Prenen JA, Schwarz F, and Thijssen JH. Interaction of delta-5-androstene-3beta, 17beta-diol with estradiol and dinydrotestosterone receptors in human myometrial and mammary cancer tissue. J Clin Endocrinol Metab 40: 373-379, 1975.
    • (1975) J Clin Endocrinol Metab , vol.40 , pp. 373-379
    • Poortman, J.1    Prenen, J.A.2    Schwarz, F.3    Thijssen, J.H.4
  • 47
    • 0033386955 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-3 is partially responsible for high-serum-induced apoptosis in PC-3 prostate cancer cells
    • Rajah R, Khare A, Lee PD, and Cohen P. Insulin-like growth factor-binding protein-3 is partially responsible for high-serum-induced apoptosis in PC-3 prostate cancer cells. J Endocrinol 163: 487-494, 1999.
    • (1999) J Endocrinol , vol.163 , pp. 487-494
    • Rajah, R.1    Khare, A.2    Lee, P.D.3    Cohen, P.4
  • 48
    • 0033168050 scopus 로고    scopus 로고
    • Chemoprevention of rat prostate carcinogenesis by early and delayed administration of dehydroepiandrosterone
    • Rao KV, Johnson WD, Bosland MC, Lubet RA, Steele VE, Kelloff GJ, and McCormick DL. Chemoprevention of rat prostate carcinogenesis by early and delayed administration of dehydroepiandrosterone. Cancer Res 59: 3084-3089, 1999.
    • (1999) Cancer Res , vol.59 , pp. 3084-3089
    • Rao, K.V.1    Johnson, W.D.2    Bosland, M.C.3    Lubet, R.A.4    Steele, V.E.5    Kelloff, G.J.6    McCormick, D.L.7
  • 49
    • 0031792660 scopus 로고    scopus 로고
    • Basal cells are progenitors of luminal cells in primary cultures of differentiating human prostatic epithelium. Extended culturing of androgen-responsive human primary epithelial prostate cell isolates by continuous treatment with interstitial collagenase
    • Robinson EJ, Neal DE, Collins AT, Mitchen J, Oberley T, and Wilding G. Basal cells are progenitors of luminal cells in primary cultures of differentiating human prostatic epithelium. Extended culturing of androgen-responsive human primary epithelial prostate cell isolates by continuous treatment with interstitial collagenase. Prostate 37: 149-160, 1998.
    • (1998) Prostate , vol.37 , pp. 149-160
    • Robinson, E.J.1    Neal, D.E.2    Collins, A.T.3    Mitchen, J.4    Oberley, T.5    Wilding, G.6
  • 50
    • 0029456051 scopus 로고
    • Cancer prevention with dehydroepiandrosterone and non-androgenic structural analogs
    • Schwartz AG and Pashko LL. Cancer prevention with dehydroepiandrosterone and non-androgenic structural analogs. J Cell Biochem Suppl 22: 210-217, 1995.
    • (1995) J Cell Biochem Suppl , vol.22 , pp. 210-217
    • Schwartz, A.G.1    Pashko, L.L.2
  • 51
    • 0031718286 scopus 로고    scopus 로고
    • Comparative distribution of estrogen receptor-alpha (ER-alpha) and beta (ER-beta) mRNA in the rat pituitary, gonad, and reproductive tract
    • Shughrue PJ, Lane MV, Scrimo PJ, and Merchenthaler I. Comparative distribution of estrogen receptor-alpha (ER-alpha) and beta (ER-beta) mRNA in the rat pituitary, gonad, and reproductive tract. Steroids 63: 498-504, 1998.
    • (1998) Steroids , vol.63 , pp. 498-504
    • Shughrue, P.J.1    Lane, M.V.2    Scrimo, P.J.3    Merchenthaler, I.4
  • 52
    • 0035406385 scopus 로고    scopus 로고
    • Estrogen receptor beta in prostate cancer: Brake pedal or accelerator?
    • Signoretti S and Loda M. Estrogen receptor beta in prostate cancer: brake pedal or accelerator? Am J Pathol 159: 13-16, 2001.
    • (2001) Am J Pathol , vol.159 , pp. 13-16
    • Signoretti, S.1    Loda, M.2
  • 53
    • 0029551622 scopus 로고
    • Variants of the human prostate LNCaP cell line as tools to study discrete components of the androgen-mediated proliferative response
    • Soto AM, Lin TM, Sakabe K, Olea N, Damassa DA, and Sonnenschein C. Variants of the human prostate LNCaP cell line as tools to study discrete components of the androgen-mediated proliferative response. Oncol Res 7: 545-558, 1995.
    • (1995) Oncol Res , vol.7 , pp. 545-558
    • Soto, A.M.1    Lin, T.M.2    Sakabe, K.3    Olea, N.4    Damassa, D.A.5    Sonnenschein, C.6
  • 54
    • 0031816232 scopus 로고    scopus 로고
    • The actions of exogenous dehydroepiandrosterone in experimental animals and humans
    • Svec F and Porter JR. The actions of exogenous dehydroepiandrosterone in experimental animals and humans. Proc Soc Exp Biol Med 218: 174-191, 1998.
    • (1998) Proc Soc Exp Biol Med , vol.218 , pp. 174-191
    • Svec, F.1    Porter, J.R.2
  • 56
  • 58
    • 4544302443 scopus 로고    scopus 로고
    • Dehydroepiandrosterone increases endothelial cell proliferation in vitro and improves endothelial function in vivo by mechanisms independent of androgen and estrogen receptors
    • Williams MR, Dawood T, Ling S, Dai A, Lew R, Myles K, Funder JW, Sudhir K, and Komesaroff PA. Dehydroepiandrosterone increases endothelial cell proliferation in vitro and improves endothelial function in vivo by mechanisms independent of androgen and estrogen receptors. J Clin Endocrinol Metab 89: 4708-4715, 2004.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 4708-4715
    • Williams, M.R.1    Dawood, T.2    Ling, S.3    Dai, A.4    Lew, R.5    Myles, K.6    Funder, J.W.7    Sudhir, K.8    Komesaroff, P.A.9
  • 59
    • 0033305556 scopus 로고    scopus 로고
    • Differential posttranscriptional regulation of androgen receptor gene expression by androgen in prostate and breast cancer cells
    • Yeap BB, Krueger RG, and Leedman PJ. Differential posttranscriptional regulation of androgen receptor gene expression by androgen in prostate and breast cancer cells. Endocrinology 140: 3282-3291, 1999.
    • (1999) Endocrinology , vol.140 , pp. 3282-3291
    • Yeap, B.B.1    Krueger, R.G.2    Leedman, P.J.3
  • 60
    • 0032743557 scopus 로고    scopus 로고
    • Two mutations identified in the androgen receptor of the new human prostate cancer cell line MDA PCa 2a
    • Zhao XY, Boyle B, Krishnan AV, Navone NM, Peehl DM, and Feldman D. Two mutations identified in the androgen receptor of the new human prostate cancer cell line MDA PCa 2a. J Urol 162: 2192-2199, 1999.
    • (1999) J Urol , vol.162 , pp. 2192-2199
    • Zhao, X.Y.1    Boyle, B.2    Krishnan, A.V.3    Navone, N.M.4    Peehl, D.M.5    Feldman, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.