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Volumn 1155, Issue , 2009, Pages 174-186

The dual, opposing roles of estrogen in the prostate

Author keywords

Aromatase; ER ; ER ; Estrogen; Prostate; Prostatitis

Indexed keywords

ANDROGEN; AROMATASE; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GENISTEIN; GONADOTROPIN; ISOFLAVONE; PHYTOESTROGEN; TESTOSTERONE; TOREMIFENE;

EID: 61749095503     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.04360.x     Document Type: Conference Paper
Times cited : (181)

References (106)
  • 1
    • 0023395389 scopus 로고
    • The endocrinology and developmental biology of the prostate
    • Cunha, G. et al. 1987. The endocrinology and developmental biology of the prostate. Endocr. Rev. 8 : 338 362.
    • (1987) Endocr. Rev. , vol.8 , pp. 338-362
    • Cunha, G.1
  • 2
    • 0028528315 scopus 로고
    • The role of androgen in the regulation of programmed cell death/apoptosis in normal and malignant prostatic tissue
    • Isaacs, J.T., Y. Furuya & R. Berges. 1994. The role of androgen in the regulation of programmed cell death/apoptosis in normal and malignant prostatic tissue. Semin. Cancer Biol. 5 : 391 400.
    • (1994) Semin. Cancer Biol. , vol.5 , pp. 391-400
    • Isaacs, J.T.1    Furuya, Y.2    Berges, R.3
  • 3
    • 84928580276 scopus 로고
    • Studies on prostatic cancer. the effect of castration, of estrogen and of androgen interaction on serum phosphatases in metastatic carcinoma of the prostate
    • Huggins, C. & C.V. Hodges. 1941. Studies on prostatic cancer. The effect of castration, of estrogen and of androgen interaction on serum phosphatases in metastatic carcinoma of the prostate. Cancer Res. 1 : 293 297.
    • (1941) Cancer Res. , vol.1 , pp. 293-297
    • Huggins, C.1    Hodges, C.V.2
  • 4
    • 0023322003 scopus 로고
    • The prostate 41-65 years post castration. An analysis of 26 eunuchs
    • Wu, J.P. & F.L. Gu. 1987. The prostate 41-65 years post castration. An analysis of 26 eunuchs. Chin. Med. J. (Engl.) 100 : 271 272.
    • (1987) Chin. Med. J. (Engl.) , vol.100 , pp. 271-272
    • Wu, J.P.1    Gu, F.L.2
  • 6
    • 0036613014 scopus 로고    scopus 로고
    • Estradiol in elderly men
    • Vermeulen, A. et al. 2002. Estradiol in elderly men. Aging Male 5 : 98 102.
    • (2002) Aging Male , vol.5 , pp. 98-102
    • Vermeulen, A.1
  • 7
    • 0037203482 scopus 로고    scopus 로고
    • Androgens and aging men
    • Baulieu, E.E. 2002. Androgens and aging men. Mol. Cell Endocrinol. 198 : 41 49.
    • (2002) Mol. Cell Endocrinol. , vol.198 , pp. 41-49
    • Baulieu, E.E.1
  • 8
    • 0025818232 scopus 로고
    • An examination of research design effects on the association of testosterone and male aging: Results of a meta-analysis
    • Gray, A. et al. 1991. An examination of research design effects on the association of testosterone and male aging: Results of a meta-analysis. J. Clin. Epidemiol. 44 : 671 684.
    • (1991) J. Clin. Epidemiol. , vol.44 , pp. 671-684
    • Gray, A.1
  • 9
    • 0025884064 scopus 로고
    • Age, disease, and changing sex hormone levels in middle-aged men: Results of the Massachusetts Male Aging Study
    • Gray, A. et al. 1991. Age, disease, and changing sex hormone levels in middle-aged men: Results of the Massachusetts Male Aging Study. J. Clin. Endocrinol. Metab. 73 : 1016 1025.
    • (1991) J. Clin. Endocrinol. Metab. , vol.73 , pp. 1016-1025
    • Gray, A.1
  • 10
    • 85003173512 scopus 로고
    • Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone
    • Culig, Z. et al. 1993. Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone. Mol. Endocrinol. 7 : 1541 1550.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 1541-1550
    • Culig, Z.1
  • 11
    • 0033814734 scopus 로고    scopus 로고
    • Estrogens and prostatic disease. International Prostate Health Council Study Group
    • Griffiths, K. 2000. Estrogens and prostatic disease. International Prostate Health Council Study Group. Prostate 45 : 87 100.
    • (2000) Prostate , vol.45 , pp. 87-100
    • Griffiths, K.1
  • 12
    • 0020372330 scopus 로고
    • Abnormal levels of plasma hormones in men with prostate cancer: Evidence toward a "two-disease" theory
    • Zumoff, B. et al. 1982. Abnormal levels of plasma hormones in men with prostate cancer: Evidence toward a "two-disease" theory. Prostate 3 : 579 588.
    • (1982) Prostate , vol.3 , pp. 579-588
    • Zumoff, B.1
  • 13
    • 0023225306 scopus 로고
    • Aromatization of androstenedione to estrogen by benign prostatic hyperplasia, prostate cancer and expressed prostatic secretions
    • Stone, N.N. et al. 1987. Aromatization of androstenedione to estrogen by benign prostatic hyperplasia, prostate cancer and expressed prostatic secretions. Urol. Res. 15 : 165 167.
    • (1987) Urol. Res. , vol.15 , pp. 165-167
    • Stone, N.N.1
  • 14
    • 0023228599 scopus 로고
    • The possibility of aromatization of androgen in human prostate
    • Kaburagi, Y. et al. 1987. The possibility of aromatization of androgen in human prostate. J. Steroid Biochem. 26 : 739 742.
    • (1987) J. Steroid Biochem. , vol.26 , pp. 739-742
    • Kaburagi, Y.1
  • 15
    • 0027094310 scopus 로고
    • Immunohistochemical evidence of the existence and localization of aromatase in human prostatic tissues
    • Matzkin, H. & M.S. Soloway. 1992. Immunohistochemical evidence of the existence and localization of aromatase in human prostatic tissues. Prostate 21 : 309 314.
    • (1992) Prostate , vol.21 , pp. 309-314
    • Matzkin, H.1    Soloway, M.S.2
  • 16
    • 0029841137 scopus 로고    scopus 로고
    • Aromatase mRNA levels in benign prostatic hyperplasia and prostate cancer
    • Tsugaya, M. et al. 1996. Aromatase mRNA levels in benign prostatic hyperplasia and prostate cancer. Int. J. Urol. 3 : 292 296.
    • (1996) Int. J. Urol. , vol.3 , pp. 292-296
    • Tsugaya, M.1
  • 17
    • 0030898475 scopus 로고    scopus 로고
    • Aromatase in hyperplasia and carcinoma of the human prostate
    • Hiramatsu, M. et al. 1997. Aromatase in hyperplasia and carcinoma of the human prostate. Prostate 31 : 118 124.
    • (1997) Prostate , vol.31 , pp. 118-124
    • Hiramatsu, M.1
  • 18
    • 0031594509 scopus 로고    scopus 로고
    • Presence of 5alpha-reductase isozymes and aromatase in human prostate cancer cells and in benign prostate hyperplastic tissue
    • Negri-Cesi, P. et al. 1998. Presence of 5alpha-reductase isozymes and aromatase in human prostate cancer cells and in benign prostate hyperplastic tissue. Prostate 34 : 283 291.
    • (1998) Prostate , vol.34 , pp. 283-291
    • Negri-Cesi, P.1
  • 19
    • 0027362649 scopus 로고
    • Tissue-specific expression of the human aromatase cytochrome P-450 gene by alternative use of multiple exons 1 and promoters, and switching of tissue-specific exons 1 in carcinogenesis
    • Harada, N., T. Utsumi & Y. Takagi. 1993. Tissue-specific expression of the human aromatase cytochrome P-450 gene by alternative use of multiple exons 1 and promoters, and switching of tissue-specific exons 1 in carcinogenesis. Proc. Natl. Acad. Sci. USA 90 : 11312 11316.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11312-11316
    • Harada, N.1    Utsumi, T.2    Takagi, Y.3
  • 20
    • 2442486485 scopus 로고    scopus 로고
    • Local aromatase expression in human prostate is altered in malignancy
    • Ellem, S.J. et al. 2004. Local aromatase expression in human prostate is altered in malignancy. J. Clin. Endocrinol. Metab. 89 : 2434 2441.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 2434-2441
    • Ellem, S.J.1
  • 21
    • 0037643401 scopus 로고    scopus 로고
    • Transcriptional regulation of aromatase expression in human breast tissue
    • Chen, S. et al. 2002. Transcriptional regulation of aromatase expression in human breast tissue. J. Steroid Biochem. Mol. Biol. 83 : 93 99.
    • (2002) J. Steroid Biochem. Mol. Biol. , vol.83 , pp. 93-99
    • Chen, S.1
  • 22
    • 0037340808 scopus 로고    scopus 로고
    • The therapeutic potential of aromatase inhibitors
    • Miller, W.R. & J. Jackson. 2003. The therapeutic potential of aromatase inhibitors. Expert Opin. Investig. Drugs 12 : 337 351.
    • (2003) Expert Opin. Investig. Drugs , vol.12 , pp. 337-351
    • Miller, W.R.1    Jackson, J.2
  • 23
    • 0035886547 scopus 로고    scopus 로고
    • Use of the aromatase inhibitor anastrozole in the treatment of patients with advanced prostate carcinoma
    • Santen, R.J. et al. 2001. Use of the aromatase inhibitor anastrozole in the treatment of patients with advanced prostate carcinoma. Cancer 92 : 2095 2101.
    • (2001) Cancer , vol.92 , pp. 2095-2101
    • Santen, R.J.1
  • 24
    • 33644511694 scopus 로고    scopus 로고
    • Of mice and men: The evolving phenotype of aromatase deficiency
    • Jones, M.E. et al. 2006. Of mice and men: The evolving phenotype of aromatase deficiency. Trends Endocrinol. Metab. 17 : 55 64.
    • (2006) Trends Endocrinol. Metab. , vol.17 , pp. 55-64
    • Jones, M.E.1
  • 25
    • 0035015891 scopus 로고    scopus 로고
    • Elevated androgens and prolactin in aromatase deficient (ArKO) mice cause enlargement but not malignancy of the prostate gland
    • McPherson, S. et al. 2001. Elevated androgens and prolactin in aromatase deficient (ArKO) mice cause enlargement but not malignancy of the prostate gland. Endocrinol. 142 : 2458 2467.
    • (2001) Endocrinol. , vol.142 , pp. 2458-2467
    • McPherson, S.1
  • 26
    • 0002136207 scopus 로고
    • The histology of the human foetal and prepubertal prostates
    • Andrews, G. 1951. The histology of the human foetal and prepubertal prostates. J. Anat. 85 : 44 54.
    • (1951) J. Anat. , vol.85 , pp. 44-54
    • Andrews, G.1
  • 27
    • 0002587355 scopus 로고
    • The fetal and neonatal prostate
    • & In. M. Goland, Ed. Charles C. Thomas. Springfield, IL.
    • Zondek, T. & L.H. Zondek. 1975. The fetal and neonatal prostate. In Normal and Abnormal Growth of the Prostate. M. Goland, Ed. Charles C. Thomas. Springfield, IL.
    • (1975) Normal and Abnormal Growth of the Prostate.
    • Zondek, T.1    Zondek, L.H.2
  • 28
    • 0021369383 scopus 로고
    • Squamous metaplasia of the verumontanum with obstruction due to hypertrophy: Long-term effects of estrogen on the prostate in an aging male-to-female transsexual
    • Goodwin, W.E. & R.H. Cummings. 1984. Squamous metaplasia of the verumontanum with obstruction due to hypertrophy: Long-term effects of estrogen on the prostate in an aging male-to-female transsexual. J. Urol. 131 : 553 554.
    • (1984) J. Urol. , vol.131 , pp. 553-554
    • Goodwin, W.E.1    Cummings, R.H.2
  • 29
    • 0018758951 scopus 로고
    • Biochemical and histological studies on prostates in castrated dogs after treatment with androstenediol, oestradiol and cyproterone acetate
    • Tunn, U. et al. 1979. Biochemical and histological studies on prostates in castrated dogs after treatment with androstenediol, oestradiol and cyproterone acetate. Acta Endocrinol. (Copenh.) 91 : 373 384.
    • (1979) Acta Endocrinol. (Copenh.) , vol.91 , pp. 373-384
    • Tunn, U.1
  • 30
    • 0023119420 scopus 로고
    • Effects of zeranol on reproduction in beef bulls: Scrotal circumference, serving ability, semen characteristics, and pathologic changes of the reproductive organs
    • Deschamps, J.C. et al. 1987. Effects of zeranol on reproduction in beef bulls: Scrotal circumference, serving ability, semen characteristics, and pathologic changes of the reproductive organs. Am. J. Vet. Res. 48 : 137 147.
    • (1987) Am. J. Vet. Res. , vol.48 , pp. 137-147
    • Deschamps, J.C.1
  • 31
    • 0026514682 scopus 로고
    • Changing cytokeratin expression patterns in diethylstilbestrol dipropionate-induced metaplastic lesions of the goat prostate
    • Weijman, J. et al. 1992. Changing cytokeratin expression patterns in diethylstilbestrol dipropionate-induced metaplastic lesions of the goat prostate. Vet. Q. 14 : 2 7.
    • (1992) Vet. Q. , vol.14 , pp. 2-7
    • Weijman, J.1
  • 32
    • 0020403662 scopus 로고
    • Morphology of rat prostatic lobes and seminal vesicles after long-term estrogen treatment
    • Andersson, H. & L.E. Tisell. 1982. Morphology of rat prostatic lobes and seminal vesicles after long-term estrogen treatment. Acta Pathol. Microbiol. Immunol. Scand. [A] 90 : 441 448.
    • (1982) Acta Pathol. Microbiol. Immunol. Scand. [A] , vol.90 , pp. 441-448
    • Andersson, H.1    Tisell, L.E.2
  • 33
    • 0020329294 scopus 로고
    • Phenotypic modulation of the canine prostate after long-term treatment with androgens and estrogens
    • Aumuller, G. et al. 1982. Phenotypic modulation of the canine prostate after long-term treatment with androgens and estrogens. Prostate 3 : 361 373.
    • (1982) Prostate , vol.3 , pp. 361-373
    • Aumuller, G.1
  • 34
    • 0019178066 scopus 로고
    • Effects of prenatal maternal estrogen on the male urogenital system
    • Driscoll, S.G. & S.H. Taylor. 1980. Effects of prenatal maternal estrogen on the male urogenital system. Obstet. Gynecol. 56 : 537 542.
    • (1980) Obstet. Gynecol. , vol.56 , pp. 537-542
    • Driscoll, S.G.1    Taylor, S.H.2
  • 35
    • 0024241665 scopus 로고
    • The periurethrals zone of the prostate of the cynomolgus monkey is the most sensitive prostate part for an estrogenic stimulus
    • Habenicht, U.F. & M.F. el Etreby. 1988. The periurethrals zone of the prostate of the cynomolgus monkey is the most sensitive prostate part for an estrogenic stimulus. Prostate 13 : 305 316.
    • (1988) Prostate , vol.13 , pp. 305-316
    • Habenicht, U.F.1    El Etreby, M.F.2
  • 36
    • 0029819169 scopus 로고    scopus 로고
    • Effects of estrogens only on the prostates of aging men
    • van Kesteren, P. et al. (1996. Effects of estrogens only on the prostates of aging men. J. Urol. 156 : 1349 1353.
    • (1996) J. Urol. , vol.156 , pp. 1349-1353
    • Van Kesteren, P.1
  • 37
    • 0025838142 scopus 로고
    • Regional differences in the prostate of the neonatally estrogenized mouse
    • Pylkkanen, L. et al. 1991. Regional differences in the prostate of the neonatally estrogenized mouse. Prostate 18 : 117 129.
    • (1991) Prostate , vol.18 , pp. 117-129
    • Pylkkanen, L.1
  • 38
    • 0025200416 scopus 로고
    • Clinical, pathological and histopathological findings in lambs implanted with a growth-promoting product containing progesterone and oestradiol
    • Randles, J.L. 1990. Clinical, pathological and histopathological findings in lambs implanted with a growth-promoting product containing progesterone and oestradiol. J. S. Afr. Vet. Assoc. 61 : 126 127.
    • (1990) J. S. Afr. Vet. Assoc. , vol.61 , pp. 126-127
    • Randles, J.L.1
  • 39
    • 0023883907 scopus 로고
    • Temporal and spatial factors in diethylstilbestrol-induced squamous metaplasia of the developing human prostate
    • Sugimura, Y. et al. 1988. Temporal and spatial factors in diethylstilbestrol-induced squamous metaplasia of the developing human prostate. Hum. Pathol. 19 : 133 139.
    • (1988) Hum. Pathol. , vol.19 , pp. 133-139
    • Sugimura, Y.1
  • 40
    • 0035017872 scopus 로고    scopus 로고
    • The metaplastic effects of estrogen on mouse prostate epithelium: Proliferation of cells with basal cell phenotype
    • Risbridger, G.P. et al. 2001. The metaplastic effects of estrogen on mouse prostate epithelium: Proliferation of cells with basal cell phenotype. Endocrinol. 142 : 2443 2450.
    • (2001) Endocrinol. , vol.142 , pp. 2443-2450
    • Risbridger, G.P.1
  • 41
    • 0028213891 scopus 로고
    • The proliferative function of basal cells in the normal and hyperplastic human prostate
    • Bonkhoff, H., U. Stein & K. Remberger. 1994. The proliferative function of basal cells in the normal and hyperplastic human prostate. Prostate 24 : 114 118.
    • (1994) Prostate , vol.24 , pp. 114-118
    • Bonkhoff, H.1    Stein, U.2    Remberger, K.3
  • 42
    • 17744375346 scopus 로고    scopus 로고
    • Altered structure and function of reproductive organs in transgenic male mice overexpressing human aromatase
    • Li, X. et al. 2001. Altered structure and function of reproductive organs in transgenic male mice overexpressing human aromatase. Endocrinol. 142 : 2435 2442.
    • (2001) Endocrinol. , vol.142 , pp. 2435-2442
    • Li, X.1
  • 43
    • 0035881269 scopus 로고    scopus 로고
    • Estrogen imprinting of the developing prostate gland is mediated through stromal estrogen receptor alpha: Studies with alphaERKO and betaERKO mice
    • Prins, G.S. et al. 2001. Estrogen imprinting of the developing prostate gland is mediated through stromal estrogen receptor alpha: Studies with alphaERKO and betaERKO mice. Cancer Res. 61 : 6089 6097.
    • (2001) Cancer Res. , vol.61 , pp. 6089-6097
    • Prins, G.S.1
  • 44
    • 0027315502 scopus 로고
    • Prostatic dysplasia associated with increased expression of c-myc in neonatally estrogenized mice
    • Pylkkanen, L. et al. 1993. Prostatic dysplasia associated with increased expression of c-myc in neonatally estrogenized mice. J. Urol. 149 : 1593 1601.
    • (1993) J. Urol. , vol.149 , pp. 1593-1601
    • Pylkkanen, L.1
  • 45
    • 0018248029 scopus 로고
    • Sex steroid imprinting of the immature prostate. Long-term effects
    • Rajfer, J. & D.S. Coffey. 1978. Sex steroid imprinting of the immature prostate. Long-term effects. Invest. Urol. 16 : 186 190.
    • (1978) Invest. Urol. , vol.16 , pp. 186-190
    • Rajfer, J.1    Coffey, D.S.2
  • 46
    • 0026767048 scopus 로고
    • Neonatal estrogen exposure induces lobe-specific alterations in adult rat prostate androgen receptor expression
    • Prins, G.S. 1992. Neonatal estrogen exposure induces lobe-specific alterations in adult rat prostate androgen receptor expression. Endocrinol. 130 : 3703 3714.
    • (1992) Endocrinol. , vol.130 , pp. 3703-3714
    • Prins, G.S.1
  • 47
    • 0027245474 scopus 로고
    • Effects of neonatal estrogen exposure on prostatic secretory genes and their correlation with androgen receptor expression in the separate prostate lobes of the adult rat
    • Prins, G. et al. 1993. Effects of neonatal estrogen exposure on prostatic secretory genes and their correlation with androgen receptor expression in the separate prostate lobes of the adult rat. Endocrinol. 132 : 2387 2398.
    • (1993) Endocrinol. , vol.132 , pp. 2387-2398
    • Prins, G.1
  • 48
    • 0019511153 scopus 로고
    • Functional development of sex accessory organs of the male rat. Use of oestradiol benzoate to identify the neonatal period as critical for development of normal protein-synthetic and secretory capabilities
    • Higgins, S.J. et al. 1981. Functional development of sex accessory organs of the male rat. Use of oestradiol benzoate to identify the neonatal period as critical for development of normal protein-synthetic and secretory capabilities. Biochem. J. 194 : 895 905.
    • (1981) Biochem. J. , vol.194 , pp. 895-905
    • Higgins, S.J.1
  • 49
    • 0023025045 scopus 로고
    • The differential effects of neonatal androgen, estrogen and progesterone on adult rat prostate growth
    • Naslund, M.J. & D.S. Coffey. 1986. The differential effects of neonatal androgen, estrogen and progesterone on adult rat prostate growth. J. Urol. 136: 1136-.
    • (1986) J. Urol. , vol.136 , pp. 1136
    • Naslund, M.J.1    Coffey, D.S.2
  • 50
    • 0001054269 scopus 로고    scopus 로고
    • Developmental estrogenization of the prostate gland
    • R. Naz, Ed. CRC Press. New York.
    • Prins, G. 1997. Developmental estrogenization of the prostate gland. In Prostate: Basic and Clinical Aspects. R. Naz, Ed 245 263. CRC Press. New York.
    • (1997) Prostate: Basic and Clinical Aspects. , pp. 245-263
    • Prins, G.1
  • 51
    • 0023005643 scopus 로고
    • Morphometric analysis of the rat ventral prostate and seminal vesicles during prepubertal development: Effects of neonatal treatment with estrogen
    • Gaytan, F. et al. 1986. Morphometric analysis of the rat ventral prostate and seminal vesicles during prepubertal development: Effects of neonatal treatment with estrogen. Biol. Reprod. 35 : 219 225.
    • (1986) Biol. Reprod. , vol.35 , pp. 219-225
    • Gaytan, F.1
  • 52
    • 0018760437 scopus 로고
    • Effects of neonatal steroids on male sex tissues
    • Rajfer, J. & D.S. Coffey. 1979. Effects of neonatal steroids on male sex tissues. Invest. Urol. 17 : 3 8.
    • (1979) Invest. Urol. , vol.17 , pp. 3-8
    • Rajfer, J.1    Coffey, D.S.2
  • 53
    • 0032806836 scopus 로고    scopus 로고
    • Morphometric studies of neonatal estrogen imprinting in the mature mouse prostate
    • Singh, J. & D.J. Handelsman. 1999. Morphometric studies of neonatal estrogen imprinting in the mature mouse prostate. J. Endocrinol. 162 : 39 48.
    • (1999) J. Endocrinol. , vol.162 , pp. 39-48
    • Singh, J.1    Handelsman, D.J.2
  • 54
    • 0033049010 scopus 로고    scopus 로고
    • Imprinting by neonatal sex steroids on the structure and function of the mature mouse prostate
    • Singh, J. & D.J. Handelsmann. 1999. Imprinting by neonatal sex steroids on the structure and function of the mature mouse prostate. Biol. Reprod. 61 : 200 208.
    • (1999) Biol. Reprod. , vol.61 , pp. 200-208
    • Singh, J.1    Handelsmann, D.J.2
  • 55
    • 0017655350 scopus 로고
    • Gonadotrophin-releasing hormone deficiency in a mutant mouse with hypogonadism
    • Cattanach, B.M. et al. 1977. Gonadotrophin-releasing hormone deficiency in a mutant mouse with hypogonadism. Nature 269 : 338 340.
    • (1977) Nature , vol.269 , pp. 338-340
    • Cattanach, B.M.1
  • 56
    • 0036892154 scopus 로고    scopus 로고
    • Direct response of the murine prostate gland and seminal vesicles to estradiol
    • Bianco, J.J. et al. 2002. Direct response of the murine prostate gland and seminal vesicles to estradiol. Endocrinol. 143 : 4922 4933.
    • (2002) Endocrinol. , vol.143 , pp. 4922-4933
    • Bianco, J.J.1
  • 57
    • 33744744433 scopus 로고    scopus 로고
    • Transient neonatal estrogen exposure to estrogen-deficient mice (aromatase knockout) reduces prostate weight and induces inflammation in late life
    • Bianco, J.J. et al. 2006. Transient neonatal estrogen exposure to estrogen-deficient mice (aromatase knockout) reduces prostate weight and induces inflammation in late life. Am. J. Pathol. 168 : 1869 1878.
    • (2006) Am. J. Pathol. , vol.168 , pp. 1869-1878
    • Bianco, J.J.1
  • 58
    • 0032805744 scopus 로고    scopus 로고
    • Proliferative inflammatory atrophy of the prostate: Implications for prostatic carcinogenesis
    • De Marzo, A.M. et al. 1999. Proliferative inflammatory atrophy of the prostate: Implications for prostatic carcinogenesis. Am. J. Pathol. 155 : 1985 1992.
    • (1999) Am. J. Pathol. , vol.155 , pp. 1985-1992
    • De Marzo, A.M.1
  • 59
    • 78649353107 scopus 로고    scopus 로고
    • The role of inflammation in the pathogenesis of prostate cancer
    • discussion S11-2.
    • Nelson, W.G. et al. 2004. The role of inflammation in the pathogenesis of prostate cancer. J. Urol. 172 : S6 11 discussion S11-2.
    • (2004) J. Urol. , vol.172
    • Nelson, W.G.1
  • 60
    • 22844438244 scopus 로고    scopus 로고
    • Prostate carcinogenesis and inflammation: Emerging insights
    • Palapattu, G.S. et al. 2005. Prostate carcinogenesis and inflammation: Emerging insights. Carcinogen 26 : 1170 1181.
    • (2005) Carcinogen , vol.26 , pp. 1170-1181
    • Palapattu, G.S.1
  • 61
    • 0002970318 scopus 로고
    • Benign nodular hyperplasia of the prostate: A review
    • Franks, L.M. 1954. Benign nodular hyperplasia of the prostate: A review. Ann. R. Coll. Surgeons 14 : 92 106.
    • (1954) Ann. R. Coll. Surgeons , vol.14 , pp. 92-106
    • Franks, L.M.1
  • 62
    • 0026455732 scopus 로고
    • The prostate - Overview: Recent insights and speculations
    • Gardner, W.A., Jr. & B.D. Bennett. 1992. The prostate - Overview: Recent insights and speculations. Monogr. Pathol. 129 148.
    • (1992) Monogr. Pathol. , pp. 129-148
    • Gardner W.A., Jr.1    Bennett, B.D.2
  • 63
    • 0023156939 scopus 로고
    • Prostatic intra-epithelial neoplasia and early invasion in prostate cancer
    • Bostwick, D.G. & M.K. Brawer. 1987. Prostatic intra-epithelial neoplasia and early invasion in prostate cancer. Cancer 59 : 788 794.
    • (1987) Cancer , vol.59 , pp. 788-794
    • Bostwick, D.G.1    Brawer, M.K.2
  • 64
    • 0026577388 scopus 로고
    • Prostatic intraepithelial neoplasia: A premalignant lesion
    • Brawer, M.K. 1992. Prostatic intraepithelial neoplasia: A premalignant lesion. Hum. Pathol. 23 : 242 248.
    • (1992) Hum. Pathol. , vol.23 , pp. 242-248
    • Brawer, M.K.1
  • 65
    • 0028109167 scopus 로고
    • Sex hormone-induced nuclear DNA damage and lipid peroxidation in the dorsolateral prostates of Noble rats
    • Ho, S.M. & D. Roy. 1994. Sex hormone-induced nuclear DNA damage and lipid peroxidation in the dorsolateral prostates of Noble rats. Cancer Lett. 84 : 155 162.
    • (1994) Cancer Lett. , vol.84 , pp. 155-162
    • Ho, S.M.1    Roy, D.2
  • 66
    • 33645653031 scopus 로고    scopus 로고
    • Steroid hormones stimulate human prostate cancer progression and metastasis
    • Ricke, W.A. et al. 2006. Steroid hormones stimulate human prostate cancer progression and metastasis. Int. J. Cancer 118 : 2123 2131.
    • (2006) Int. J. Cancer , vol.118 , pp. 2123-2131
    • Ricke, W.A.1
  • 67
    • 0021745167 scopus 로고
    • Age, environmental factors and prostatic cancer
    • Hill, P., L. Garbaczewski & A.R. Walker. 1984. Age, environmental factors and prostatic cancer. Med. Hypotheses 14 : 29 39.
    • (1984) Med. Hypotheses , vol.14 , pp. 29-39
    • Hill, P.1    Garbaczewski, L.2    Walker, A.R.3
  • 68
    • 0033660592 scopus 로고    scopus 로고
    • The role of steroid hormones in prostate carcinogenesis
    • Bosland, M.C. 2000. The role of steroid hormones in prostate carcinogenesis. J. Natl. Cancer Inst. Monogr. 39 66.
    • (2000) J. Natl. Cancer Inst. Monogr. , pp. 39-66
    • Bosland, M.C.1
  • 69
    • 0025941349 scopus 로고
    • Peripheral hormone levels in controls and patients with prostatic cancer or benign prostatic hyperplasia: Results from the Dutch-Japanese case-control study
    • de Jong, F.H. et al. 1991. Peripheral hormone levels in controls and patients with prostatic cancer or benign prostatic hyperplasia: results from the Dutch-Japanese case-control study. Cancer Res. 51 : 3445 3450.
    • (1991) Cancer Res. , vol.51 , pp. 3445-3450
    • De Jong, F.H.1
  • 70
    • 0020073188 scopus 로고
    • Mechanistic studies on C-19 demethylation in oestrogen biosynthesis
    • Akhtar, M. et al. 1982. Mechanistic studies on C-19 demethylation in oestrogen biosynthesis. Biochem. J. 201 : 569 580.
    • (1982) Biochem. J. , vol.201 , pp. 569-580
    • Akhtar, M.1
  • 71
    • 0019827338 scopus 로고
    • Mechanism of estrogen biosynthesis. Participation of multiple enzyme sites in placental aromatase hydroxylations
    • Fishman, J. & J. Goto. 1981. Mechanism of estrogen biosynthesis. Participation of multiple enzyme sites in placental aromatase hydroxylations. J. Biol. Chem. 256 : 4466 4471.
    • (1981) J. Biol. Chem. , vol.256 , pp. 4466-4471
    • Fishman, J.1    Goto, J.2
  • 72
    • 0028693017 scopus 로고
    • Aromatase gene expression in adipose tissue: Relationship to breast cancer
    • Simpson, E.R. et al. 1994. Aromatase gene expression in adipose tissue: Relationship to breast cancer. Int. J. Fertil. Menopausal. Stud. 39 : 75 83.
    • (1994) Int. J. Fertil. Menopausal. Stud. , vol.39 , pp. 75-83
    • Simpson, E.R.1
  • 73
    • 0035862917 scopus 로고    scopus 로고
    • Evidence that epithelial and mesenchymal estrogen receptor-alpha mediates effects of estrogen on prostatic epithelium
    • Risbridger, G. et al. 2001. Evidence that epithelial and mesenchymal estrogen receptor-alpha mediates effects of estrogen on prostatic epithelium. Dev. Biol. 229 : 432 442.
    • (2001) Dev. Biol. , vol.229 , pp. 432-442
    • Risbridger, G.1
  • 74
    • 43249092379 scopus 로고    scopus 로고
    • Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signaling
    • Ricke, W.A. et al. 2007. Prostatic hormonal carcinogenesis is mediated by in situ estrogen production and estrogen receptor alpha signaling. Faseb J. 22 (5 1512 1520.
    • (2007) Faseb J. , vol.22 , Issue.5 , pp. 1512-1520
    • Ricke, W.A.1
  • 75
    • 0036494569 scopus 로고    scopus 로고
    • Toremifene prevents prostate cancer in the transgenic adenocarcinoma of mouse prostate model
    • Raghow, S. et al. 2002. Toremifene prevents prostate cancer in the transgenic adenocarcinoma of mouse prostate model. Cancer Res. 62 : 1370 1376.
    • (2002) Cancer Res. , vol.62 , pp. 1370-1376
    • Raghow, S.1
  • 76
    • 33746524463 scopus 로고    scopus 로고
    • Toremifene for the prevention of prostate cancer in men with high grade prostatic intraepithelial neoplasia: Results of a double-blind, placebo controlled, phase IIB clinical trial
    • discussion 970-971.
    • Price, D. et al. 2006. Toremifene for the prevention of prostate cancer in men with high grade prostatic intraepithelial neoplasia: results of a double-blind, placebo controlled, phase IIB clinical trial. J. Urol. 176 : 965 970 discussion 970-971.
    • (2006) J. Urol. , vol.176 , pp. 965-970
    • Price, D.1
  • 77
    • 0030797569 scopus 로고    scopus 로고
    • Effect of testosterone and estradiol in a man with aromatase deficiency
    • Carani, C. et al. 1997. Effect of testosterone and estradiol in a man with aromatase deficiency. N. Engl. J. Med. 337 : 91 95.
    • (1997) N. Engl. J. Med. , vol.337 , pp. 91-95
    • Carani, C.1
  • 78
    • 0033326235 scopus 로고    scopus 로고
    • Aromatase deficiency caused by a novel P450arom gene mutation: Impact of absent estrogen production on serum gonadotropin concentration in a boy
    • Deladoey, J. et al. 1999. Aromatase deficiency caused by a novel P450arom gene mutation: Impact of absent estrogen production on serum gonadotropin concentration in a boy. J. Clin. Endocrinol. Metab. 84 : 4050 4054.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 4050-4054
    • Deladoey, J.1
  • 79
    • 0036925191 scopus 로고    scopus 로고
    • Impact of estrogen replacement therapy in a male with congenital aromatase deficiency caused by a novel mutation in the CYP19 gene
    • Herrmann, B.L. et al. 2002. Impact of estrogen replacement therapy in a male with congenital aromatase deficiency caused by a novel mutation in the CYP19 gene. J. Clin. Endocrinol. Metab. 87 : 5476 5484.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 5476-5484
    • Herrmann, B.L.1
  • 80
    • 10744225853 scopus 로고    scopus 로고
    • Dysmetabolic syndrome in a man with a novel mutation of the aromatase gene: Effects of testosterone, alendronate, and estradiol treatment
    • Maffei, L. et al. 2004. Dysmetabolic syndrome in a man with a novel mutation of the aromatase gene: Effects of testosterone, alendronate, and estradiol treatment. J. Clin. Endocrinol. Metab. 89 : 61 70.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 61-70
    • Maffei, L.1
  • 81
    • 0028792229 scopus 로고
    • Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens
    • Morishima, A. et al. 1995. Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. J. Clin. Endocrinol. Metab. 80 : 3689 3698.
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 3689-3698
    • Morishima, A.1
  • 82
    • 0033305733 scopus 로고    scopus 로고
    • Estrogen: Consequences and implications of human mutations in synthesis and action
    • Grumbach, M.M. & R.J. Auchus. 1999. Estrogen: Consequences and implications of human mutations in synthesis and action. J. Clin. Endocrinol. Metab. 84 : 4677 4694.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 4677-4694
    • Grumbach, M.M.1    Auchus, R.J.2
  • 83
    • 0037205931 scopus 로고    scopus 로고
    • Congenital estrogen deficiency in men: A new syndrome with different phenotypes; Clinical and therapeutic implications in men
    • Rochira, V. et al. 2002. Congenital estrogen deficiency in men: A new syndrome with different phenotypes; clinical and therapeutic implications in men. Mol. Cell Endocrinol. 193 : 19 28.
    • (2002) Mol. Cell Endocrinol. , vol.193 , pp. 19-28
    • Rochira, V.1
  • 84
    • 0033994049 scopus 로고    scopus 로고
    • Phytoestrogens and prostate disease
    • Adlercreutz, H. et al. 2000. Phytoestrogens and prostate disease. J. Nutr. 130 : 658S 659S.
    • (2000) J. Nutr. , vol.130
    • Adlercreutz, H.1
  • 85
    • 0032460067 scopus 로고    scopus 로고
    • Phytoestrogens and diseases of the prostate gland
    • Griffiths, K. et al. 1998. Phytoestrogens and diseases of the prostate gland. Bailliere's Clin. Endocrinol. Metab. 12 : 625 647.
    • (1998) Bailliere's Clin. Endocrinol. Metab. , vol.12 , pp. 625-647
    • Griffiths, K.1
  • 87
    • 0028842284 scopus 로고
    • Soybean phytoestrogen intake and cancer risk
    • Adlercreutz, C.H. et al. 1995. Soybean phytoestrogen intake and cancer risk. J. Nutr. 125 : 757S 770S.
    • (1995) J. Nutr. , vol.125
    • Adlercreutz, C.H.1
  • 88
    • 0030579801 scopus 로고    scopus 로고
    • Cloning of a novel receptor expressed in rat prostate and ovary
    • Kuiper, G.G. et al. 1996. Cloning of a novel receptor expressed in rat prostate and ovary. Proc. Natl. Acad. Sci. USA 93 : 5925 5930.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5925-5930
    • Kuiper, G.G.1
  • 89
    • 14344284951 scopus 로고    scopus 로고
    • A role for estrogen receptor beta in the regulation of growth of the ventral prostate
    • Weihua, Z. et al. 2001. A role for estrogen receptor beta in the regulation of growth of the ventral prostate. Proc. Natl. Acad. Sci. USA 98 : 6330 6335.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 6330-6335
    • Weihua, Z.1
  • 90
    • 3042586045 scopus 로고    scopus 로고
    • Estrogen receptor beta regulates epithelial cellular differentiation in the mouse ventral prostate
    • Imamov, O. et al. 2004. Estrogen receptor beta regulates epithelial cellular differentiation in the mouse ventral prostate. Proc. Natl. Acad. Sci. USA 101 : 9375 9380.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 9375-9380
    • Imamov, O.1
  • 91
    • 33846413629 scopus 로고    scopus 로고
    • Essential role for estrogen receptor beta in stromal-epithelial regulation of prostatic hyperplasia
    • McPherson, S.J. et al. 2007. Essential role for estrogen receptor beta in stromal-epithelial regulation of prostatic hyperplasia. Endocrinol. 148 : 566 574.
    • (2007) Endocrinol. , vol.148 , pp. 566-574
    • McPherson, S.J.1
  • 93
    • 20044371621 scopus 로고    scopus 로고
    • Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activity
    • Chadwick, C.C. et al. 2005. Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activity. Proc. Natl. Acad. Sci. USA 102 : 2543 2548.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 2543-2548
    • Chadwick, C.C.1
  • 94
    • 0141525429 scopus 로고    scopus 로고
    • Evaluation of an estrogen receptor-beta agonist in animal models of human disease
    • Harris, H.A. et al. 2003. Evaluation of an estrogen receptor-beta agonist in animal models of human disease. Endocrinol. 144 : 4241 4249.
    • (2003) Endocrinol. , vol.144 , pp. 4241-4249
    • Harris, H.A.1
  • 95
    • 38649140488 scopus 로고    scopus 로고
    • The role of estrogens and estrogen receptors in normal prostate growth and disease
    • Prins, G.S. & K.S. Korach. 2008. The role of estrogens and estrogen receptors in normal prostate growth and disease. Steroids 73 : 233 244.
    • (2008) Steroids , vol.73 , pp. 233-244
    • Prins, G.S.1    Korach, K.S.2
  • 96
    • 34548825107 scopus 로고    scopus 로고
    • Delay of postnatal maturation sensitizes the mouse prostate to testosterone-induced pronounced hyperplasia: Protective role of estrogen receptor-beta
    • Savolainen, S. et al. 2007. Delay of postnatal maturation sensitizes the mouse prostate to testosterone-induced pronounced hyperplasia: Protective role of estrogen receptor-beta. Am. J. Pathol. 171 : 1013 1022.
    • (2007) Am. J. Pathol. , vol.171 , pp. 1013-1022
    • Savolainen, S.1
  • 97
    • 0035082124 scopus 로고    scopus 로고
    • Estrogen receptors alpha and beta in the normal, hyperplastic and carcinomatous human prostate
    • Royuela, M. et al. 2001. Estrogen receptors alpha and beta in the normal, hyperplastic and carcinomatous human prostate. J. Endocrinol. 168 : 447 454.
    • (2001) J. Endocrinol. , vol.168 , pp. 447-454
    • Royuela, M.1
  • 98
    • 0034999987 scopus 로고    scopus 로고
    • Loss of estrogen receptor beta expression in malignant human prostate cells in primary cultures and in prostate cancer tissues
    • Pasquali, D. et al. 2001. Loss of estrogen receptor beta expression in malignant human prostate cells in primary cultures and in prostate cancer tissues. J. Clin. Endocrinol. Metab. 86 : 2051 2055.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 2051-2055
    • Pasquali, D.1
  • 99
    • 0035408472 scopus 로고    scopus 로고
    • Comparative studies of the estrogen receptors beta and alpha and the androgen receptor in normal human prostate glands, dysplasia, and in primary and metastatic carcinoma
    • Leav, I. et al. 2001. Comparative studies of the estrogen receptors beta and alpha and the androgen receptor in normal human prostate glands, dysplasia, and in primary and metastatic carcinoma. Am. J. Pathol. 159 : 79 92.
    • (2001) Am. J. Pathol. , vol.159 , pp. 79-92
    • Leav, I.1
  • 100
    • 0035878926 scopus 로고    scopus 로고
    • Frequent loss of estrogen receptor-beta expression in prostate cancer
    • Horvath, L.G. et al. 2001. Frequent loss of estrogen receptor-beta expression in prostate cancer. Cancer Res. 61 : 5331 5335.
    • (2001) Cancer Res. , vol.61 , pp. 5331-5335
    • Horvath, L.G.1
  • 101
    • 0037304336 scopus 로고    scopus 로고
    • Differential expression of the estrogen receptor beta (ERbeta) in human prostate tissue, premalignant changes, and in primary, metastatic, and recurrent prostatic adenocarcinoma
    • Fixemer, T., K. Remberger & H. Bonkhoff. 2003. Differential expression of the estrogen receptor beta (ERbeta) in human prostate tissue, premalignant changes, and in primary, metastatic, and recurrent prostatic adenocarcinoma. Prostate 54 : 79 87.
    • (2003) Prostate , vol.54 , pp. 79-87
    • Fixemer, T.1    Remberger, K.2    Bonkhoff, H.3
  • 102
    • 4944246588 scopus 로고    scopus 로고
    • Loss of ERbeta expression as a common step in estrogen-dependent tumor progression
    • Bardin, A. et al. 2004. Loss of ERbeta expression as a common step in estrogen-dependent tumor progression. Endocr. Relat. Cancer 11 : 537 551.
    • (2004) Endocr. Relat. Cancer , vol.11 , pp. 537-551
    • Bardin, A.1
  • 103
    • 2442676740 scopus 로고    scopus 로고
    • Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis
    • Zhu, X. et al. 2004. Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis. Am. J. Pathol. 164 : 2003 2012.
    • (2004) Am. J. Pathol. , vol.164 , pp. 2003-2012
    • Zhu, X.1
  • 104
    • 0035886471 scopus 로고    scopus 로고
    • CpG hypermethylation of the promoter region inactivates the estrogen receptor-beta gene in patients with prostate carcinoma
    • Nojima, D. et al. 2001. CpG hypermethylation of the promoter region inactivates the estrogen receptor-beta gene in patients with prostate carcinoma. Cancer 92 : 2076 2083.
    • (2001) Cancer , vol.92 , pp. 2076-2083
    • Nojima, D.1
  • 105
    • 0036907418 scopus 로고    scopus 로고
    • Induction of apoptosis in low- to moderate-grade human prostate carcinoma by red clover-derived dietary isoflavones
    • Jarred, R.A. et al. 2002. Induction of apoptosis in low- to moderate-grade human prostate carcinoma by red clover-derived dietary isoflavones. Cancer Epidemiol. Biomarkers Prev. 11 : 1689 1696.
    • (2002) Cancer Epidemiol. Biomarkers Prev. , vol.11 , pp. 1689-1696
    • Jarred, R.A.1
  • 106
    • 0035884610 scopus 로고    scopus 로고
    • Genistein in the diet reduces the incidence of poorly differentiated prostatic adenocarcinoma in transgenic mice (TRAMP)
    • Mentor-Marcel, R. et al. 2001. Genistein in the diet reduces the incidence of poorly differentiated prostatic adenocarcinoma in transgenic mice (TRAMP). Cancer Res. 61 : 6777 6782.
    • (2001) Cancer Res. , vol.61 , pp. 6777-6782
    • Mentor-Marcel, R.1


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