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Volumn 59, Issue 5, 2011, Pages 909-917

Cytoplasmic expression of oestrogen receptor beta (ERβ) as a prognostic factor in vulvar squamous cell carcinoma in elderly women

Author keywords

Ki67; Oestrogen receptor beta; P21; Prognosis; Vulvar cancer

Indexed keywords

ESTROGEN RECEPTOR BETA; KI 67 ANTIGEN; PROTEIN P21;

EID: 81555214742     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2011.04029.x     Document Type: Article
Times cited : (12)

References (40)
  • 1
    • 67650385302 scopus 로고    scopus 로고
    • American Cancer Society. Atlanta, GA: American Cancer Society
    • American Cancer Society. Cancer facts and figures 2009. Atlanta, GA: American Cancer Society, 2009.
    • (2009) Cancer facts and figures 2009
  • 2
    • 33746606765 scopus 로고    scopus 로고
    • Horner MJ, Ries LAG, Krapcho M et al. eds. Bethesda, MD: National Cancer Institute. Available at:, based on November 2008 SEER data submission, posted to the SEER website, 2009 (last accessed August 2010)
    • Horner MJ, Ries LAG, Krapcho M et al. eds. SEER cancer statistics review, 1975-2006. Bethesda, MD: National Cancer Institute. Available at:, based on November 2008 SEER data submission, posted to the SEER website, 2009 (last accessed August 2010).
    • SEER cancer statistics review, 1975-2006
  • 3
    • 70350591990 scopus 로고    scopus 로고
    • Is the incidence of invasive vulvar cancer increasing in the United States?
    • Bodelon C, Madeleine MM, Voigt LF, Weiss NS. Is the incidence of invasive vulvar cancer increasing in the United States? Cancer Causes Control 2009; 20; 1779-1782.
    • (2009) Cancer Causes Control , vol.20 , pp. 1779-1782
    • Bodelon, C.1    Madeleine, M.M.2    Voigt, L.F.3    Weiss, N.S.4
  • 5
    • 39249084652 scopus 로고    scopus 로고
    • Demographic, clinical, and treatment trends among women diagnosed with vulvar cancer in the United States
    • Stroup AM, Harlan LC, Trimble EL. Demographic, clinical, and treatment trends among women diagnosed with vulvar cancer in the United States. Gynecol. Oncol. 2008; 108; 577-583.
    • (2008) Gynecol. Oncol. , vol.108 , pp. 577-583
    • Stroup, A.M.1    Harlan, L.C.2    Trimble, E.L.3
  • 6
    • 0027439865 scopus 로고
    • DNA ploidy, proliferation index, grade, and stage as prognostic factors for vulvar squamous cell carcinomas
    • Dolan JR, McCall AR, Gooneratne S, Walter S, Lansky DM. DNA ploidy, proliferation index, grade, and stage as prognostic factors for vulvar squamous cell carcinomas. Gynecol. Oncol. 1993; 48; 232-235.
    • (1993) Gynecol. Oncol. , vol.48 , pp. 232-235
    • Dolan, J.R.1    McCall, A.R.2    Gooneratne, S.3    Walter, S.4    Lansky, D.M.5
  • 7
    • 0030998186 scopus 로고    scopus 로고
    • A multivariate analysis of clinical and morphological prognostic factors in squamous cell carcinoma of the vulva
    • Smyczek-Gargya B, Volz B, Geppert M, Dietl J. A multivariate analysis of clinical and morphological prognostic factors in squamous cell carcinoma of the vulva. Gynecol. Obstet. Invest. 1997; 43; 261-267.
    • (1997) Gynecol. Obstet. Invest. , vol.43 , pp. 261-267
    • Smyczek-Gargya, B.1    Volz, B.2    Geppert, M.3    Dietl, J.4
  • 8
    • 0031907849 scopus 로고    scopus 로고
    • The management of squamous cell vulval cancer: a population based retrospective study of 411 cases
    • Rhodes CA, Cummins C, Shafi MI. The management of squamous cell vulval cancer: a population based retrospective study of 411 cases. Br. J. Obstet. Gynaecol. 1998; 105; 200-205.
    • (1998) Br. J. Obstet. Gynaecol. , vol.105 , pp. 200-205
    • Rhodes, C.A.1    Cummins, C.2    Shafi, M.I.3
  • 9
    • 0036900317 scopus 로고    scopus 로고
    • Local relapse in patients treated for squamous cell vulvar carcinoma: incidence and prognostic value
    • Rouzier R, Haddad B, Plantier F, Dubois P, Pelisse M, Paniel BJ. Local relapse in patients treated for squamous cell vulvar carcinoma: incidence and prognostic value. Obstet. Gynecol. 2002; 100; 1159-1167.
    • (2002) Obstet. Gynecol. , vol.100 , pp. 1159-1167
    • Rouzier, R.1    Haddad, B.2    Plantier, F.3    Dubois, P.4    Pelisse, M.5    Paniel, B.J.6
  • 10
    • 33745887540 scopus 로고    scopus 로고
    • Clinical and pathological prognostic factors in squamous cell carcinoma of the vulva
    • Raspagliesi F, Hanozet F, Ditto A et al. Clinical and pathological prognostic factors in squamous cell carcinoma of the vulva. Gynecol. Oncol. 2006; 102; 333-337.
    • (2006) Gynecol. Oncol. , vol.102 , pp. 333-337
    • Raspagliesi, F.1    Hanozet, F.2    Ditto, A.3
  • 11
    • 0025905208 scopus 로고
    • Assessment of current International Federation of Gynecology and Obstetrics staging of vulvar carcinoma relative to prognostic factors for survival (a Gynecologic Oncology Group study)
    • Homesley HD, Bundy BN, Sedlis A et al. Assessment of current International Federation of Gynecology and Obstetrics staging of vulvar carcinoma relative to prognostic factors for survival (a Gynecologic Oncology Group study). Am. J. Obstet. Gynecol. 1991; 164; 997-1003.
    • (1991) Am. J. Obstet. Gynecol. , vol.164 , pp. 997-1003
    • Homesley, H.D.1    Bundy, B.N.2    Sedlis, A.3
  • 12
    • 61849126321 scopus 로고    scopus 로고
    • A review of molecular pathological markers in vulvar carcinoma: lack of application in clinical practice [Review]
    • Knopp S, Tropè C, Nesland JM, Holm R. A review of molecular pathological markers in vulvar carcinoma: lack of application in clinical practice [Review]. J. Clin. Pathol. 2009; 62; 212-218.
    • (2009) J. Clin. Pathol. , vol.62 , pp. 212-218
    • Knopp, S.1    Tropè, C.2    Nesland, J.M.3    Holm, R.4
  • 13
    • 79951592109 scopus 로고    scopus 로고
    • Changes in the expression of oestrogen receptors and E-cadherin as molecular markers of progression from normal epithelium to invasive cancer in elderly patients with vulvar squamous cell carcinoma: a pilot study
    • Zannoni GF, Prisco MG, Vellone VG, De Stefano I, Scambia G, Gallo D. Changes in the expression of oestrogen receptors and E-cadherin as molecular markers of progression from normal epithelium to invasive cancer in elderly patients with vulvar squamous cell carcinoma: a pilot study. Histopathology 2011; 58; 265-275.
    • (2011) Histopathology , vol.58 , pp. 265-275
    • Zannoni, G.F.1    Prisco, M.G.2    Vellone, V.G.3    De Stefano, I.4    Scambia, G.5    Gallo, D.6
  • 14
    • 0025601703 scopus 로고
    • Immunohistochemical investigations of estrogen receptors in normal and neoplastic squamous epithelium of the vulva
    • Mosny DS, Brito F, Bender HG. Immunohistochemical investigations of estrogen receptors in normal and neoplastic squamous epithelium of the vulva. J. Reprod. Med. 1990; 35; 1005-1007.
    • (1990) J. Reprod. Med. , vol.35 , pp. 1005-1007
    • Mosny, D.S.1    Brito, F.2    Bender, H.G.3
  • 15
    • 0018242819 scopus 로고
    • Histologic malignancy grading in invasive squamous cell carcinoma of the vulva
    • Kabulski Z, Frankman O. Histologic malignancy grading in invasive squamous cell carcinoma of the vulva. Int. J. Gynaecol. Obstet. 19781979; 16; 233-237.
    • (1978) Int. J. Gynaecol. Obstet. , vol.16 , pp. 233-237
    • Kabulski, Z.1    Frankman, O.2
  • 16
    • 64049094855 scopus 로고    scopus 로고
    • Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium
    • Pecorelli S. Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int. J. Gynaecol. Obstet. 2009; 105; 103-104.
    • (2009) Int. J. Gynaecol. Obstet. , vol.105 , pp. 103-104
    • Pecorelli, S.1
  • 18
    • 33645958590 scopus 로고    scopus 로고
    • Estradiol and phytoestrogens differently influence the rodent postmenopausal mammary gland
    • Gallo D, Zannoni GF, Martinelli E et al. Estradiol and phytoestrogens differently influence the rodent postmenopausal mammary gland. Menopause 2006; 13; 72-79.
    • (2006) Menopause , vol.13 , pp. 72-79
    • Gallo, D.1    Zannoni, G.F.2    Martinelli, E.3
  • 19
    • 52649152266 scopus 로고    scopus 로고
    • Nuclear and cytoplasmic expression of ERbeta1, ERbeta2, and ERbeta5 identifies distinct prognostic outcome for breast cancer patients
    • Shaaban AM, Green AR, Karthik S et al. Nuclear and cytoplasmic expression of ERbeta1, ERbeta2, and ERbeta5 identifies distinct prognostic outcome for breast cancer patients. Clin. Cancer Res. 2008; 14; 5228-5235.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 5228-5235
    • Shaaban, A.M.1    Green, A.R.2    Karthik, S.3
  • 20
    • 58849143026 scopus 로고    scopus 로고
    • Estrogen receptor beta functions through nongenomic mechanisms in lung cancer cells
    • Zhang G, Liu X, Farkas AM et al. Estrogen receptor beta functions through nongenomic mechanisms in lung cancer cells. Mol. Endocrinol. 2009; 23; 146-156.
    • (2009) Mol. Endocrinol. , vol.23 , pp. 146-156
    • Zhang, G.1    Liu, X.2    Farkas, A.M.3
  • 21
    • 34548076290 scopus 로고    scopus 로고
    • Membrane-associated estrogen receptor signaling pathways in human cancers
    • Pietras RJ, Márquez-Garbán DC. Membrane-associated estrogen receptor signaling pathways in human cancers. Clin. Cancer Res. 2007; 13; 4672-4676.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 4672-4676
    • Pietras, R.J.1    Márquez-Garbán, D.C.2
  • 23
    • 1642535535 scopus 로고    scopus 로고
    • Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest
    • Paruthiyil S, Parmar H, Kerekatte V, Cunha GR, Firestone GL, Leitman DC. Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest. Cancer Res. 2004; 64; 423-428.
    • (2004) Cancer Res. , vol.64 , pp. 423-428
    • Paruthiyil, S.1    Parmar, H.2    Kerekatte, V.3    Cunha, G.R.4    Firestone, G.L.5    Leitman, D.C.6
  • 24
    • 1242300083 scopus 로고    scopus 로고
    • Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D
    • Strom A, Hartman J, Foster JS, Kietz S, Wimalasena J, Gustafsson JA. Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D. Proc. Natl Acad. Sci. USA 2004; 101; 1566-1571.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 1566-1571
    • Strom, A.1    Hartman, J.2    Foster, J.S.3    Kietz, S.4    Wimalasena, J.5    Gustafsson, J.A.6
  • 25
    • 34249659228 scopus 로고    scopus 로고
    • Estrogen receptor beta (ERbeta) and inhibition of prostate cancer cell proliferation: studies on the possible mechanism of action in DU145 cells
    • Pravettoni A, Mornati O, Martini PG et al. Estrogen receptor beta (ERbeta) and inhibition of prostate cancer cell proliferation: studies on the possible mechanism of action in DU145 cells. Mol. Cell. Endocrinol. 2007; 263; 46-54.
    • (2007) Mol. Cell. Endocrinol. , vol.263 , pp. 46-54
    • Pravettoni, A.1    Mornati, O.2    Martini, P.G.3
  • 26
    • 34447096900 scopus 로고    scopus 로고
    • Estrogen receptor {beta}1 exerts antitumoral effects on SK-OV-3 ovarian cancer cells
    • Treeck O, Pfeiler G, Mitter D, Lattrich C, Piendl G, Ortmann O. Estrogen receptor {beta}1 exerts antitumoral effects on SK-OV-3 ovarian cancer cells. J. Endocrinol. 2007; 193; 421-433.
    • (2007) J. Endocrinol. , vol.193 , pp. 421-433
    • Treeck, O.1    Pfeiler, G.2    Mitter, D.3    Lattrich, C.4    Piendl, G.5    Ortmann, O.6
  • 27
    • 67649424560 scopus 로고    scopus 로고
    • p21 in cancer: intricate networks and multiple activities
    • Abbas T, Dutta A. p21 in cancer: intricate networks and multiple activities. Nat. Rev. Cancer 2009; 9; 400-414.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 28
    • 67649210771 scopus 로고    scopus 로고
    • p21(WAF1/CIP1) and cancer: a shifting paradigm?
    • Gartel AL. p21(WAF1/CIP1) and cancer: a shifting paradigm? Biofactors 2009; 35; 161-164.
    • (2009) Biofactors , vol.35 , pp. 161-164
    • Gartel, A.L.1
  • 29
  • 32
    • 33846925340 scopus 로고    scopus 로고
    • Margin distance and other clinico-pathologic prognostic factors in vulvar carcinoma: a multivariate analysis
    • Chan JK, Sugiyama V, Pham H et al. Margin distance and other clinico-pathologic prognostic factors in vulvar carcinoma: a multivariate analysis. Gynecol. Oncol. 2007; 104; 636-641.
    • (2007) Gynecol. Oncol. , vol.104 , pp. 636-641
    • Chan, J.K.1    Sugiyama, V.2    Pham, H.3
  • 33
    • 0029065594 scopus 로고
    • The importance of the groin node status for the survival of T1 and T2 vulval carcinoma patients
    • Burger MP, Hollema H, Emanuels AG, Krans M, Pras E, Bouma J. The importance of the groin node status for the survival of T1 and T2 vulval carcinoma patients. Gynecol. Oncol. 1995; 57; 327-334.
    • (1995) Gynecol. Oncol. , vol.57 , pp. 327-334
    • Burger, M.P.1    Hollema, H.2    Emanuels, A.G.3    Krans, M.4    Pras, E.5    Bouma, J.6
  • 34
    • 0034234628 scopus 로고    scopus 로고
    • Patterns of recurrence in patients with squamous cell carcinoma of the vulva. A multicenter CTF Study
    • Maggino T, Landoni F, Sartori E et al. Patterns of recurrence in patients with squamous cell carcinoma of the vulva. A multicenter CTF Study. Cancer 2000; 89; 116-122.
    • (2000) Cancer , vol.89 , pp. 116-122
    • Maggino, T.1    Landoni, F.2    Sartori, E.3
  • 35
    • 61449245756 scopus 로고    scopus 로고
    • Clinicopathological prognostic factors and patterns of recurrence in vulvar cancer
    • Woelber L, Mahner S, Voelker K et al. Clinicopathological prognostic factors and patterns of recurrence in vulvar cancer. Anticancer Res. 2009; 29; 545-552.
    • (2009) Anticancer Res. , vol.29 , pp. 545-552
    • Woelber, L.1    Mahner, S.2    Voelker, K.3
  • 36
    • 77957353834 scopus 로고    scopus 로고
    • Changes in the immune system during menopause and aging [Review]
    • Gameiro C, Romao F. Changes in the immune system during menopause and aging [Review]. Front. Biosci. 2010; 2; 1299-1303.
    • (2010) Front. Biosci. , vol.2 , pp. 1299-1303
    • Gameiro, C.1    Romao, F.2
  • 37
    • 80053207646 scopus 로고    scopus 로고
    • Two distinct pathways to development of squamous cell carcinoma of the vulva
    • Article ID 951250, 7 pages, 2011. doi: 10.1155/2011/951250
    • Ueda Y, Enomoto T, Kimura T, Yoshino K, Fujita M, Kimura T. Two distinct pathways to development of squamous cell carcinoma of the vulva. J. Skin Cancer 2011; Article ID 951250, 7 pages, 2011. doi: 10.1155/2011/951250.
    • (2011) J. Skin Cancer
    • Ueda, Y.1    Enomoto, T.2    Kimura, T.3    Yoshino, K.4    Fujita, M.5    Kimura, T.6
  • 38
    • 64049117133 scopus 로고    scopus 로고
    • Revised FIGO staging for carcinoma of the vulva
    • Hacker NF. Revised FIGO staging for carcinoma of the vulva. Int. J. Gynaecol. Obstet. 2009; 105; 105-106.
    • (2009) Int. J. Gynaecol. Obstet. , vol.105 , pp. 105-106
    • Hacker, N.F.1
  • 40
    • 47249138273 scopus 로고    scopus 로고
    • Selective estrogen receptor modulator medicinal chemistry at Merck. A review [Review]
    • Blizzard TA. Selective estrogen receptor modulator medicinal chemistry at Merck. A review [Review]. Curr. Top. Med. Chem. 2008; 8; 792-812.
    • (2008) Curr. Top. Med. Chem. , vol.8 , pp. 792-812
    • Blizzard, T.A.1


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