Estrogen receptor alpha (ER-α) and beta (ER-β) mRNAs in normal ovary, ovarian serous cystadenocarcinoma and ovarian cancer cell lines: Down- regulation of ER-β in neoplastic tissues

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 3, 1998, Pages 1025-1028

  Brandenberger, Alfred W ^a   Tee, Meng Kian ^a   Jaffe, Robert B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; MESSENGER RNA; RECEPTOR SUBUNIT;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYSTADENOCARCINOMA; EPITHELIUM CELL; FEMALE; FERTILIZATION IN VITRO; GRANULOSA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; OVARY CARCINOMA; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION;

BLOTTING, NORTHERN; CYSTADENOCARCINOMA, SEROUS; DOWN-REGULATION; FEMALE; GRANULOSA CELLS; HUMANS; NUCLEIC ACID HYBRIDIZATION; OVARIAN NEOPLASMS; OVARY; RECEPTORS, ESTROGEN; REFERENCE VALUES; RIBONUCLEASES; RNA, MESSENGER; TUMOR CELLS, CULTURED;

FALLOPIA;

EID: 0004629130     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.3.1025     Document Type: Article

References (21)

1. Parker SL, Tong T, Bolden S, Wingo PA. 1996 Cancer statistics, 1996. CA Cancer J Clin. 46:5-27.
2. Clinton GM, Hua W. 1997 Estrogen action in human ovarian cancer. Crit Rev Oncol Hemat. 25:1-9.
3. Auchus JA, Fuqua SAW. 1994 The oestrogen receptor. Bailliere Clin Endocrinol Metab. 8:433-449.
4. Kuiper GGJM, Enmark E, Puelto-Huiko M, Nilsson S, Gustafsson JA. 1996 Cloning of a novel estrogen receptor expressed in rat prostate and ovary. Proc Natl Acad Sci USA. 93:2925-2930.
5. Mosselman S, Polman J, Dijkema R. 1996 ER-β: Identification and characterization of a novel human estrogen receptor. FEBS Letters. 392:49-53.
6. Byers M, Kuiper GGJM, Gustafsson JA, Park-Sarge OK. 1997 Estrogen receptor-β mRNA expression in rat ovary: Down-regulation by gonadotropins. Mol Endocrinol. 11:172-182.
7. Brandenberger AW, Tee MK, Lee JY, Chao V, Jaffe RB. 1997 Tissue distribution of estrogen receptors alpha (ER-α) and beta (ER-β) mRNA in the midgestational human fetus. J Clin Endocrinol Metab. 82:3509-3512.
8. Maines-Bandiera SL, Kruk PA, Auersperg N. 1992 Simian Virus 40-transformed human ovarian surface epithelial cells escape normal growth controls but retain morphogenetic responses to extracellular matrix. Am J Obstet Gynecol. 167:729-735
9. Sambrook J, Fritsch EF, Maniatis T. 1989 Extraction, purification, and analysis of messenger RNA from eucaryotic cells. In: Molecular Cloning, 2nd ed. New York: Cold Spring Harbor Laboratory Press; 7.71-7.78.
10. Green S, Walter P, Kumar V, et al. 1986 Human estrogen receptor cDNA: sequence, expression, and homology to v-erb-A. Nature. 320:134-139.
11. Enmark E, Pelto-Huikko M, Grandien K et al. 1997 Human estrogen receptor β-gene structure, chromosomal localization, and expression pattern. J Clin Endocrinol Metab. 82:4258-4265.
12. Saunders PTK, Maguire SM, Gaughan J, Millar MR. 1997 Expression of oestrogen receptor beta (ERβ) in multiple rat tissues visualised by immunohistochemistry. J Endocrinol. 154:R13-R16.
13. Kuiper GGJM, Carlsson B, Grandien K, et al. 1997 Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology. 138:863-870.
14. Galli MC, DeGiovanni C, Nicoletti G, et al. 1981 The occurrence of multiple steroid hormone receptors in disease-free and neoplastic human ovary. Cancer. 47:1297-1302.
15. Scambia G, Benedetti-Panici P, Ferrandina G, et al. 1995 Epidermal growth factor, oestrogen and progesterone receptor expression in primary ovarian cancer: correlation with clinical outcome and response to chemotherapy. Br J Cancer. 72:361-366.
16. Gelmann EP. 1997 Tamoxifen for the treatment of malignancies other than breast and endometrial carcinoma. Seminars in Oncol. 24(Supp 1):S65-S70.
17. Hua W, Christianson T, Rougeot C, Rochefort H, Clinton GM. 1995 SKOV3 ovarian carcinoma cells have functional estrogen receptor but are growth-resistant to estrogen and antiestrogens. J Steroid Biochem Molec Biol. 55:279-289.
18. Hatch KD, Beecham JB, Blessing JA, Creasman WT. 1991 Responsiveness of patients with advanced ovarian carcinoma to tamoxifen. Cancer. 68:269-271.
19. Cowley SM, Hoare S, Mosselman S, Parker MG. 1997 Estrogen receptors α and β form heterodimers on DNA. J Biol Chem. 32:19858-19862.
20. Paech K, Webb P, Kuiper GGJM, Nilsson S, Gustafsson JA, Kushner P, Scanlan TS. 1997 Differential ligand activation of estrogen receptors ERα and ERβ at AP1 sites. Science. 277:1508-1510.
21. Hedden A, Muller V, Jensen EV. A new interpretation of antiestrogen action. 1995 Ann NY Acad Sci. 761:109-120.