Correlation of mRNA for oestrogen receptor beta splice variants ERβ 1, ERβ2/ERβcx and ERβ5 with outcome in endocrine-treated breast cancer

Journal of Molecular Endocrinology

Volumn 33, Issue 3, 2004, Pages 773-782

  Davies, Mike P A ^c   O'Neill, P A ^c   Innes, H ^c   Sibson, D R ^c   Prime, W ^a   Holcombe, C ^b   Foster, C S ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

^c CLATTERBRIDGE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANASTROZOLE; BIOLOGICAL MARKER; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; KI 67 ANTIGEN; MESSENGER RNA; PROGESTERONE RECEPTOR; RECEPTOR SUBTYPE; TAMOXIFEN;

ADULT; AGE; AGED; ANTIGEN EXPRESSION; ARTICLE; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER HORMONE THERAPY; CANCER SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENE IDENTIFICATION; HORMONE RESPONSE; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MEDICAL PARAMETERS; MULTIVARIATE ANALYSIS; POSTMENOPAUSE; PREDICTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; TUMOR VOLUME;

ALTERNATIVE SPLICING; BREAST NEOPLASMS; ESTROGEN RECEPTOR BETA; FOLLOW-UP STUDIES; HORMONES; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASM STAGING; RNA, MESSENGER; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 11244287448     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.1.01574     Document Type: Article

References (38)

1. Bieche I, Parfait B, Laurendeau I, Girault I, Vidaud M & Lidereau R 2001 Quantification of estrogen receptor alpha and beta expression in sporadic breast cancer. Oncogene 20 8109-8115.
2. Cowley SM, Hoare S, Mosselman S & Parker MG 1997 Estrogen receptors alpha and beta form heterodimers on DNA. Journal of Biological Chemistry 272 19858-19862.
3. de Cremoux P, Tran-Perennou C, Elie C, Boudou E, Barbaroux C, Poupon MF, De Rycke Y, Asselain B & Magdelenat H 2002 Quantitation of estradiol receptors alpha and beta and progesterone receptors in human breast tumors by real-time reverse transcription-polymerase chain reaction. Correlation with protein assays. Biochemical Pharmacology 64 507-515.
4. Cullen R, Maguire TM, McDermott EW, Hill AD, O'Higgins NJ & Duffy MJ 2001 Studies on oestrogen receptor-alpha and -beta mRNA in breast cancer. European Journal of Cancer 37 1118-1122.
5. Dotzlaw H, Leygue E, Watson PH & Murphy LC 1999 Estrogen receptor-beta messenger RNA expression in human breast tumor biopsies: relationship to steroid receptor status and regulation by progestins. Cancer Research 59 529-532.
6. Enmark E, Pelto-Huikko M, Grandien K, Lagercrantz S, Lagercrantz J, Fried G, Nordenskjold M & Gustafsson JA 1997 Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern. Journal of Clinical Endocrinology and Metabolism 82 4258-4265.
7. Fuqua SA, Schiff R, Parra I, Moore JT, Mohsin SK, Osborne CK, Clark GM & Allred DC 2003 Estrogen receptor beta protein in human breast cancer: correlation with clinical tumor parameters. Cancer Research 63 2434-2439.
8. Iwao K, Miyoshi Y, Egawa C, Ikeda N & Noguchi S 2000a Quantitative analysis of estrogen receptor-beta mRNA and its variants in human breast cancers. International Journal of Cancer 88 733-736.
9. Iwao K, Miyoshi Y, Egawa C, Ikeda N, Tsukamoto F & Noguchi S 2000b Quantitative analysis of estrogen receptor-alpha and -beta messenger RNA expression in breast carcinoma by real-time polymerase chain reaction. Cancer 89 1732-1738.
10. Jarvinen TA, Pelto-Huikko M, Holli K & Isola J 2000 Estrogen receptor beta is coexpressed with ERalpha and PR and associated with nodal status, grade, and proliferation rate in breast cancer. American Journal of Pathology 156 29-35.
11. Knowlden JM, Gee JM, Robertson JF, Ellis IO & Nicholson RI 2000 A possible divergent role for the oestrogen receptor alpha and beta subtypes in clinical breast cancer. International Journal of Cancer 89 209-212.
12. Kurebayashi J, Otsuki T, Kunisue H, Tanaka K, Yamamoto S & Sonoo H 2000 Expression levels of estrogen receptor-alpha, estrogen receptor-beta, coactivators, and corepressors in breast cancer. Clinical Cancer Research 6 512-518.
13. Leygue E, Dotzlaw H, Watson PH & Murphy LC 1998 Altered estrogen receptor alpha and beta messenger RNA expression during human breast tumorigenesis. Cancer Research 58 3197-3201.
14. Leygue E, Dotzlaw H, Watson PH & Murphy LC 1999 Expression of estrogen receptor beta1, beta2, and beta5 messenger RNAs in human breast tissue. Cancer Research 59 1175-1179.
15. Locker GY 1998 Hormonal therapy of breast cancer. Cancer Treatment Reviews 24 221-240.
16. Mann S, Laucirica R, Carlson N, Younes PS, Ali N, Younes A, Li Y & Younes M 2001 Estrogen receptor beta expression in invasive breast cancer. Human Pathology 32 113-118.
17. Miyoshi Y, Taguchi T, Gustafsson JA & Noguchi S 2001 Clinicopathological characteristics of estrogen receptor-betapositive human breast cancers. Japanese Journal of Cancer Research 92 1057-1061.
18. Moore JT, McKee DD, Slentz-Kesler K, Moore LB, Jones SA, Horne EL, Su JL, Kliewer SA, Lehmann JM & Willson TM 1998 Cloning and characterization of human estrogen receptor beta isoforms. Biochemical and Biophysical Research Communications 247 75-78.
19. National Coordinating Group for Breast Screening Pathology 1997 Pathology Reporting in Breast Cancer Screening. NHSBSP Publication No. 3. NHSBSP Publications, NHS Breast Screening Programme, Sheffield.
20. Ogawa S, Inoue S, Watanabe T, Orimo A, Hosoi T, Ouchi Y & Muramatsu. M 1998 Molecular cloning and characterization of human estrogen receptor betacx: a potential inhibitor of estrogen action in human. Nucleic Acids Research 26 3505-3512.
21. Omoto Y, Inoue S, Ogawa S, Toyama T, Yamashita H, Muramatsu M, Kobayashi S & Iwase H 2001 Clinical value of the wild-type estrogen receptor beta expression in breast cancer. Cancer Letters 163 207-212.
22. Omoto Y, Kobayashi S, Inoue S, Ogawa S, Toyama T, Yamashita H, Muramatsu M, Gustafsson JA & Iwase H 2002 Evaluation of oestrogen receptor beta wild-type and variant protein expression, and relationship with clinicopathological factors in breast cancers. European Journal of Cancer 38 380-386.
23. Palmieri C, Lam EW, Mansi J, MacDonald C, Shousha S, Madden P, Omoto Y, Sunters A, Warner M, Gustafsson JA et al. 2004a The expression of ERbetacx in human breast cancer and the relationship to endocrine therapy and survival. Clinical Cancer Research 10 2421-2428.
24. Palmieri C, Saji S, Sakaguchi H, Cheng G, Sunters A, O'Hare MJ, Warner M, Gustafsson JA, Coombes RC & Lam EW 2004b The expression of ERβ and its variants, but not ERα, in adult human mammary fibroblasts. Journal of Molecular Endocrinology 33 55-50.
25. Peng B, Lu B, Leygue E & Murphy LC 2003 Putative functional characteristics of human estrogen receptor-beta isoforms. Journal of Molecular Endocrinology 30 13-29.
26. Pertschuk LP & Axiotis CA 1999 Steroid hormone receptor immunohistochemistry in breast cancer: past, present, and future. Breast Journal 5 3-12.
27. Saji S, Omoto Y, Shimizu C, Warner M, Hayashi Y, Horiguchi S, Watanabe T, Hayashi S, Gustafsson JA & Toi M 2002 Expression of estrogen receptor (ER) (beta)cx protein in ER(alpha)-positive breast cancer: specific correlation with progesterone receptor. Cancer Research 62 4849-4853.
28. Saunders PT 1998 Oestrogen receptor beta (ER beta). Reviews of Reproduction 3 164-171.
29. Saunders PT, Millar MR, Macpherson S, Irvine DS, Groome NP, Evans LR, Sharpe RM & Scobie GA 2002 ERbeta1 and the ERbeta2 splice variant (ERbetacx/beta2) are expressed in distinct cell populations in the adult human testis. Journal of Clinical Endocrinology and Metabolism 87 2706-2715.
30. Shaaban AM, Sloane JP, West CR & Foster CS 2002 Breast cancer risk in usual ductal hyperplasia is defined by estrogen receptor-alpha and Ki-6 7 expression. American Journal of Pathology 160 597-604.
31. Shaaban AM, O'Neill PA, Davies MP, Sibson R, West CR, Smith PH & Foster CS 2003a Declining estrogen receptor-beta expression defines malignant progression of human breast neoplasia. American Journal of Surgical Pathology 27 1502-1512.
32. Shaaban AM, O'Neill P & Foster CS 2003b Re: Skliris et al. Evaluation of seven oestrogen receptor beta antibodies for immunohistochemistry, Western blotting, and flow cytometry in human breast tissue (Journal of Pathology 2002 196 155-162). Journal of Pathology 199 130.
33. Skliris GP, Carder PJ, Lansdown MR & Speirs V 2001 Immunohistochemical detection of ERbeta in breast cancer: towards more detailed receptor profiling? British Journal of Cancer 84 1095-1098.
34. Speirs V & Kerin MJ 2000 Prognostic significance of oestrogen receptor beta in breast cancer. British Journal of Surgery 87 405-409.
35. Speirs V, Malone C, Walton DS, Kerin MJ & Atkin SL 1999a Increased expression of estrogen receptor beta mRNA in tamoxifen-resistant breast cancer patients. Cancer Research 59 5421-5424.
36. Speirs V, Parkes AT, Kerin MJ, Walton DS, Carleton PJ, Fox JN & Atkin SL 1999b Coexpression of estrogen receptor alpha and beta: poor prognostic factors in human breast cancer? Cancer Research 59 525-528.
37. Tong D, Schuster E, Seifert M, Czerwenka K, Leodolte S & Zeillinger R 2002 Expression of estrogen receptor beta isoforms in human breast cancer tissues and cell lines. Breast Cancer Research and Treatment 71 249-255.
38. Vladusic EA, Hornby AE, Guerra-Vladusic F & Lupu R 1998 Expression of estrogen receptor beta messenger RNA variant in breast cancer. Cancer Research 58 210-214.